Luca Della Santina, PhD

Title(s)Assistant Professor, Ophthalmology
SchoolSchool of Medicine
Address10 Koret Way, #001
San Francisco CA 94117
ORCID ORCID Icon0000-0001-6036-1295 Additional info
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    Collapse education and training
    University of Pisa, ItalyM.S.Medicinal Chemistry
    University of Pisa, ItalyPharmDPharmacy
    University of Pisa, ItalyPhDNeuroscience
    University of Washington, SeattlePostDocNeurodegeneration

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    Collapse Research 
    Collapse research activities and funding
    TRACHOMA SURVEILLANCE AT SCALE: AUTOMATIC DISEASE GRADING OF EYELID PHOTOS
    NIH R21EY032567May 1, 2021 - Apr 30, 2023
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Impact of Photoreceptor Loss on Retinal Circuitry. Annu Rev Vis Sci. 2021 09 15; 7:105-128. Lee JY, Care RA, Della Santina L, Dunn FA. PMID: 34524879; PMCID: PMC8711296.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    2. Disassembly and rewiring of a mature converging excitatory circuit following injury. Cell Rep. 2021 08 03; 36(5):109463. Della Santina L, Yu AK, Harris SC, Soliño M, Garcia Ruiz T, Most J, Kuo YM, Dunn FA, Ou Y. PMID: 34348156; PMCID: PMC8381591.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    3. Scalable method for micro-CT analysis enables large scale quantitative characterization of brain lesions and implants. Sci Rep. 2020 11 30; 10(1):20851. Kastner DB, Kharazia V, Nevers R, Smyth C, Astudillo-Maya DA, Williams GM, Yang Z, Holobetz CM, Santina LD, Parkinson DY, Frank LM. PMID: 33257721; PMCID: PMC7705725.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    4. Probing ON and OFF Retinal Pathways in Glaucoma Using Electroretinography. Transl Vis Sci Technol. 2020 10; 9(11):14. Kong AW, Della Santina L, Ou Y. PMID: 33117606; PMCID: PMC7571283.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    5. A dual role for Cav1.4 Ca2+ channels in the molecular and structural organization of the rod photoreceptor synapse. Elife. 2020 09 17; 9. Maddox JW, Randall KL, Yadav RP, Williams B, Hagen J, Derr PJ, Kerov V, Della Santina L, Baker SA, Artemyev N, Hoon M, Lee A. PMID: 32940604; PMCID: PMC7561352.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    6. Mature Retina Compensates Functionally for Partial Loss of Rod Photoreceptors. Cell Rep. 2020 06 09; 31(10):107730. Care RA, Anastassov IA, Kastner DB, Kuo YM, Della Santina L, Dunn FA. PMID: 32521255; PMCID: PMC8049532.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    7. Partial Cone Loss Triggers Synapse-Specific Remodeling and Spatial Receptive Field Rearrangements in a Mature Retinal Circuit. Cell Rep. 2019 05 14; 27(7):2171-2183.e5. Care RA, Kastner DB, De la Huerta I, Pan S, Khoche A, Della Santina L, Gamlin C, Santo Tomas C, Ngo J, Chen A, Kuo YM, Ou Y, Dunn FA. PMID: 31091454; PMCID: PMC6624172.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    8. Biolistic Labeling of Retinal Ganglion Cells. Methods Mol Biol. 2018; 1695:161-170. Santina LD, Ou Y. PMID: 29190026; PMCID: PMC8724011.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    9. Selective Vulnerability of Specific Retinal Ganglion Cell Types and Synapses after Transient Ocular Hypertension. J Neurosci. 2016 08 31; 36(35):9240-52. Ou Y, Jo RE, Ullian EM, Wong RO, Della Santina L. PMID: 27581463; PMCID: PMC5005727.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    10. Glutamatergic Monopolar Interneurons Provide a Novel Pathway of Excitation in the Mouse Retina. Curr Biol. 2016 08 08; 26(15):2070-2077. Della Santina L, Kuo SP, Yoshimatsu T, Okawa H, Suzuki SC, Hoon M, Tsuboyama K, Rieke F, Wong ROL. PMID: 27426514; PMCID: PMC4980212.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    11. Who's lost first? Susceptibility of retinal ganglion cell types in experimental glaucoma. Exp Eye Res. 2017 05; 158:43-50. Della Santina L, Ou Y. PMID: 27319294; PMCID: PMC5161723.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    12. Involvement of Autophagic Pathway in the Progression of Retinal Degeneration in a Mouse Model of Diabetes. Front Cell Neurosci. 2016; 10:42. Piano I, Novelli E, Della Santina L, Strettoi E, Cervetto L, Gargini C. PMID: 26924963; PMCID: PMC4759287.
      View in: PubMed   Mentions: 46  
    13. TMEM16A is associated with voltage-gated calcium channels in mouse retina and its function is disrupted upon mutation of the auxiliary α2δ4 subunit. Front Cell Neurosci. 2015; 9:422. Caputo A, Piano I, Demontis GC, Bacchi N, Casarosa S, Della Santina L, Gargini C. PMID: 26557056; PMCID: PMC4617175.
      View in: PubMed   Mentions: 17  
    14. Illuminating the multifaceted roles of neurotransmission in shaping neuronal circuitry. Neuron. 2014 Sep 17; 83(6):1303-1318. Okawa H, Hoon M, Yoshimatsu T, Della Santina L, Wong ROL. PMID: 25233313; PMCID: PMC4168971.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    15. Functional architecture of the retina: development and disease. Prog Retin Eye Res. 2014 Sep; 42:44-84. Hoon M, Okawa H, Della Santina L, Wong RO. PMID: 24984227; PMCID: PMC4134977.
      View in: PubMed   Mentions: 232     Fields:    Translation:HumansAnimalsCells
    16. Interplay of cell-autonomous and nonautonomous mechanisms tailors synaptic connectivity of converging axons in vivo. Neuron. 2014 Apr 02; 82(1):125-37. Okawa H, Della Santina L, Schwartz GW, Rieke F, Wong RO. PMID: 24698272; PMCID: PMC3990864.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    17. Sensory experience shapes the development of the visual system's first synapse. Neuron. 2013 Dec 04; 80(5):1159-66. Dunn FA, Della Santina L, Parker ED, Wong RO. PMID: 24314727; PMCID: PMC3894852.
      View in: PubMed   Mentions: 38     Fields:    
    18. Differential progression of structural and functional alterations in distinct retinal ganglion cell types in a mouse model of glaucoma. J Neurosci. 2013 Oct 30; 33(44):17444-57. Della Santina L, Inman DM, Lupien CB, Horner PJ, Wong RO. PMID: 24174678; PMCID: PMC3812509.
      View in: PubMed   Mentions: 168     Fields:    Translation:AnimalsCells
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