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Disruption of theta-timescale spiking impairs learning but spares hippocampal replay. bioRxiv. 2025 Sep 17.
Joshi A, Comrie AE, Bray S, Mankili A, Guidera JA, Nevers R, Sun X, Monroe E, Kharazia V, Ly R, Maya DA, Morales-Rodriguez D, Yu J, Kiseleva A, Perez V, Frank LM. PMID: 41000666; PMCID: PMC12458185.
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High-density single-unit human cortical recordings using the Neuropixels probe. Neuron. 2022 08 03; 110(15):2409-2421.e3.
Chung JE, Sellers KK, Leonard MK, Gwilliams L, Xu D, Dougherty ME, Kharazia V, Metzger SL, Welkenhuysen M, Dutta B, Chang EF. PMID: 35679860.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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A versatile toolbox for studying cortical physiology in primates. Cell Rep Methods. 2022 03 28; 2(3).
Khateeb K, Bloch J, Zhou J, Rahimi M, Griggs DJ, Kharazia VN, Le MN, Wang RK, Yazdan-Shahmorad A. PMID: 35445205; PMCID: PMC9017216.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Scalable method for micro-CT analysis enables large scale quantitative characterization of brain lesions and implants. Sci Rep. 2020 11 30; 10(1):20851.
Kastner DB, Kharazia V, Nevers R, Smyth C, Astudillo-Maya DA, Williams GM, Yang Z, Holobetz CM, Santina LD, Parkinson DY, Frank LM. PMID: 33257721; PMCID: PMC7705725.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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An Integrated Brain-Machine Interface Platform With Thousands of Channels. J Med Internet Res. 2019 Oct 31; 21(10):e16194.
Musk E, Neuralink. PMID: 31642810; PMCID: PMC6914248.
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PubMed Mentions:
281 Fields:
Translation:
Humans
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A Practical Method for Creating Targeted Focal Ischemic Stroke in the Cortex of Nonhuman Primates. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:3515-3518.
Khateeb K, Yao Z, Kharazia VN, Burunova EP, Song S, Wang R, Yazdan-Shahmorad A. PMID: 31946636; PMCID: PMC8523301.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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The “sewing machine” for minimally invasive neural recording. bioRxiv 578542; doi: https://doi.org/10.1101/578542. 2019; 1-32.
Timothy L Hanson, Camilo A Diaz-Botia, Viktor Kharazia, Michel M Maharbiz, Philip N Sabes. View Publication.
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Targeted cortical reorganization using optogenetics in non-human primates. Elife. 2018 05 29; 7.
Yazdan-Shahmorad A, Silversmith DB, Kharazia V, Sabes PN. PMID: 29809133; PMCID: PMC5986269.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Widespread optogenetic expression in macaque cortex obtained with MR-guided, convection enhanced delivery (CED) of AAV vector to the thalamus. J Neurosci Methods. 2018 Jan 01; 293:347-358.
Yazdan-Shahmorad A, Tian N, Kharazia V, Samaranch L, Kells A, Bringas J, He J, Bankiewicz K, Sabes PN. PMID: 29042259.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Limited Excessive Voluntary Alcohol Drinking Leads to Liver Dysfunction in Mice. Alcohol Clin Exp Res. 2017 02; 41(2):345-358.
Wegner SA, Pollard KA, Kharazia V, Darevsky D, Perez L, Roychowdhury S, Xu A, Ron D, Nagy LE, Hopf FW. PMID: 28103636; PMCID: PMC5636002.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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A Large-Scale Interface for Optogenetic Stimulation and Recording in Nonhuman Primates. Neuron. 2016 Mar 02; 89(5):927-39.
Yazdan-Shahmorad A, Diaz-Botia C, Hanson TL, Kharazia V, Ledochowitsch P, Maharbiz MM, Sabes PN. PMID: 26875625.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. Front Neurosci. 2015; 9:487.
Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO. PMID: 26733798; PMCID: PMC4689854.
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PubMed Mentions:
86
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Increased behavioral responses to ethanol in Lmo3 knockout mice. Genes Brain Behav. 2014 Nov; 13(8):777-83.
Savarese A, Zou ME, Kharazia V, Maiya R, Lasek AW. PMID: 25176312; PMCID: PMC4442799.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption. J Neurochem. 2014 Jun; 129(6):1024-34.
Darcq E, Hamida SB, Wu S, Phamluong K, Kharazia V, Xu J, Lombroso P, Ron D. PMID: 24588427; PMCID: PMC4055745.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors. J Neurosci. 2013 Sep 04; 33(36):14369-78.
Ben Hamida S, Darcq E, Wang J, Wu S, Phamluong K, Kharazia V, Ron D. PMID: 24005290; PMCID: PMC3761047.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area. PLoS One. 2013; 8(7):e68300.
Chatterjee S, Santos N, Holgate J, Haass-Koffler CL, Hopf FW, Kharazia V, Lester H, Bonci A, Bartlett SE. PMID: 23869214; PMCID: PMC3712017.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse. Nat Neurosci. 2013 Aug; 16(8):1111-7.
Barak S, Liu F, Ben Hamida S, Yowell QV, Neasta J, Kharazia V, Janak PH, Ron D. PMID: 23792945; PMCID: PMC3725202.
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PubMed Mentions:
91 Fields:
Translation:
AnimalsCells
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The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors. J Neurosci. 2012 Nov 07; 32(45):15849-58.
Ben Hamida S, Neasta J, Lasek AW, Kharazia V, Zou M, Carnicella S, Janak PH, Ron D. PMID: 23136424; PMCID: PMC3514017.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Taok2 controls behavioral response to ethanol in mice. Genes Brain Behav. 2013 Feb; 12(1):87-97.
Kapfhamer D, Taylor S, Zou ME, Lim JP, Kharazia V, Heberlein U. PMID: 22883308; PMCID: PMC4011144.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Lmo4 in the basolateral complex of the amygdala modulates fear learning. PLoS One. 2012; 7(4):e34559.
Maiya R, Kharazia V, Lasek AW, Heberlein U. PMID: 22509321; PMCID: PMC3317997.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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PKCε phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice. J Clin Invest. 2012 Apr; 122(4):1306-15.
Wu DF, Chandra D, McMahon T, Wang D, Dadgar J, Kharazia VN, Liang YJ, Waxman SG, Dib-Hajj SD, Messing RO. PMID: 22426212; PMCID: PMC3315445.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Alk is a transcriptional target of LMO4 and ERα that promotes cocaine sensitization and reward. J Neurosci. 2011 Oct 05; 31(40):14134-41.
Lasek AW, Gesch J, Giorgetti F, Kharazia V, Heberlein U. PMID: 21976498; PMCID: PMC3197235.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption. Transl Psychiatry. 2011; 1.
Barak S, Ahmadiantehrani S, Kharazia V, Ron D. PMID: 22238721; PMCID: PMC3253655.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system. J Neurosci. 2010 Oct 27; 30(43):14502-12.
Wang J, Carnicella S, Ahmadiantehrani S, He DY, Barak S, Kharazia V, Ben Hamida S, Zapata A, Shippenberg TS, Ron D. PMID: 20980608; PMCID: PMC2981598.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
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Lmo4 in the nucleus accumbens regulates cocaine sensitivity. Genes Brain Behav. 2010 Oct; 9(7):817-24.
Lasek AW, Kapfhamer D, Kharazia V, Gesch J, Giorgetti F, Heberlein U. PMID: 20618444; PMCID: PMC3130015.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity. J Neurosci. 2010 Jun 30; 30(26):8830-40.
Kapfhamer D, Berger KH, Hopf FW, Seif T, Kharazia V, Bonci A, Heberlein U. PMID: 20592205; PMCID: PMC3842471.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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Differential regulation of behavioral tolerance to WIN55,212-2 by GASP1. Neuropsychopharmacology. 2010 May; 35(6):1363-73.
Martini L, Thompson D, Kharazia V, Whistler JL. PMID: 20164830; PMCID: PMC2953419.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Endogenous BDNF in the dorsolateral striatum gates alcohol drinking. J Neurosci. 2009 Oct 28; 29(43):13494-502.
Jeanblanc J, He DY, Carnicella S, Kharazia V, Janak PH, Ron D. PMID: 19864562; PMCID: PMC2855618.
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PubMed Mentions:
113 Fields:
Translation:
HumansAnimalsCells
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Protein kinase Cdelta regulates ethanol intoxication and enhancement of GABA-stimulated tonic current. J Neurosci. 2008 Nov 12; 28(46):11890-9.
Choi DS, Wei W, Deitchman JK, Kharazia VN, Lesscher HM, McMahon T, Wang D, Qi ZH, Sieghart W, Zhang C, Shokat KM, Mody I, Messing RO. PMID: 19005054; PMCID: PMC2688726.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. Proc Natl Acad Sci U S A. 2008 Jun 10; 105(23):8114-9.
Carnicella S, Kharazia V, Jeanblanc J, Janak PH, Ron D. PMID: 18541917; PMCID: PMC2423415.
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PubMed Mentions:
75 Fields:
Translation:
AnimalsCellsPHPublic Health
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Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence. Curr Biol. 2008 Jan 22; 18(2):129-35.
Kim JA, Bartlett S, He L, Nielsen CK, Chang AM, Kharazia V, Waldhoer M, Ou CJ, Taylor S, Ferwerda M, Cado D, Whistler JL. PMID: 18207746; PMCID: PMC2997702.
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PubMed Mentions:
58 Fields:
Translation:
Animals
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Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner. J Biol Chem. 2008 Jan 04; 283(1):301-310.
Jurd R, Thornton C, Wang J, Luong K, Phamluong K, Kharazia V, Gibb SL, Ron D. PMID: 17962190; PMCID: PMC3124443.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Amygdala protein kinase C epsilon regulates corticotropin-releasing factor and anxiety-like behavior. Genes Brain Behav. 2008 Apr; 7(3):323-33.
Lesscher HM, McMahon T, Lasek AW, Chou WH, Connolly J, Kharazia V, Messing RO. PMID: 17908177.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Acute cocaine exposure alters spine density and long-term potentiation in the ventral tegmental area. Eur J Neurosci. 2007 Aug; 26(3):749-56.
Sarti F, Borgland SL, Kharazia VN, Bonci A. PMID: 17686047.
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PubMed Mentions:
51 Fields:
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AnimalsCells
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Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1. FASEB J. 2007 Mar; 21(3):802-11.
Martini L, Waldhoer M, Pusch M, Kharazia V, Fong J, Lee JH, Freissmuth C, Whistler JL. PMID: 17197383.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8215-20.
Choi DS, Wang D, Yu GQ, Zhu G, Kharazia VN, Paredes JP, Chang WS, Deitchman JK, Mucke L, Messing RO. PMID: 16698938; PMCID: PMC1472455.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Localization of the scaffolding protein RACK1 in the developing and adult mouse brain. Brain Res. 2006 Jan 19; 1069(1):31-8.
Ashique AM, Kharazia V, Yaka R, Phamluong K, Peterson AS, Ron D. PMID: 16414032.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Dopamine responsiveness is regulated by targeted sorting of D2 receptors. Proc Natl Acad Sci U S A. 2005 Aug 09; 102(32):11521-6.
Bartlett SE, Enquist J, Hopf FW, Lee JH, Gladher F, Kharazia V, Waldhoer M, Mailliard WS, Armstrong R, Bonci A, Whistler JL. PMID: 16049099; PMCID: PMC1183554.
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PubMed Mentions:
91 Fields:
Translation:
HumansAnimalsCells
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RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction. J Neurosci. 2004 Nov 17; 24(46):10542-52.
McGough NN, He DY, Logrip ML, Jeanblanc J, Phamluong K, Luong K, Kharazia V, Janak PH, Ron D. PMID: 15548669; PMCID: PMC6730316.
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PubMed Mentions:
122 Fields:
Translation:
AnimalsCells
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Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury. J Clin Invest. 2004 Jul; 114(1):49-56.
Chou WH, Choi DS, Zhang H, Mu D, McMahon T, Kharazia VN, Lowell CA, Ferriero DM, Messing RO. PMID: 15232611; PMCID: PMC437973.
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PubMed Mentions:
82 Fields:
Translation:
AnimalsCells
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Light microscopic study of GluR1 and calbindin expression in interneurons of neocortical microgyral malformations. Neuroscience. 2003; 120(1):207-18.
Kharazia VN, Jacobs KM, Prince DA. PMID: 12849753.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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A developmental switch of AMPA receptor subunits in neocortical pyramidal neurons. J Neurosci. 2002 Apr 15; 22(8):3005-15.
Kumar SS, Bacci A, Kharazia V, Huguenard JR. PMID: 11943803; PMCID: PMC6757523.
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PubMed Mentions:
162 Fields:
Translation:
AnimalsCells
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Biochemical and morphological characterization of an intracellular membrane compartment containing AMPA receptors. Neuropharmacology. 2001 Nov; 41(6):680-92.
Lee SH, Valtschanoff JG, Kharazia VN, Weinberg R, Sheng M. PMID: 11640922.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Changes of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors in layer V of epileptogenic, chronically isolated rat neocortex. Neuroscience. 2001; 102(1):23-34.
Kharazia VN, Prince DA. PMID: 11226667.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Postlesional epilepsy: the ultimate brain plasticity. Epilepsia. 2000; 41 Suppl 6:S153-61.
Jacobs KM, Graber KD, Kharazia VN, Parada I, Prince DA. PMID: 10999537.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Immunogold localization of AMPA and NMDA receptors in somatic sensory cortex of albino rat. J Comp Neurol. 1999 Sep 20; 412(2):292-302.
Kharazia VN, Weinberg RJ. PMID: 10441757.
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PubMed Mentions:
85 Fields:
Translation:
AnimalsCells
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Mechanisms underlying epileptogenesis in cortical malformations. Epilepsy Res. 1999 Sep; 36(2-3):165-88.
Jacobs KM, Kharazia VN, Prince DA. PMID: 10515164.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Nitric oxide synthase-containing projections to the ventrobasal thalamus in the rat. Anat Embryol (Berl). 1999 Sep; 200(3):265-81.
Usunoff KG, Kharazia VN, Valtschanoff JG, Schmidt HH, Weinberg RJ. PMID: 10463342.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Immunocytochemical demonstration of reduced glutathione in neurons of rat forebrain. Brain Res. 1999 Jan 30; 817(1-2):199-205.
Maybodi L, Pow DV, Kharazia VN, Weinberg RJ. PMID: 9889366.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Direct interaction of CASK/LIN-2 and syndecan heparan sulfate proteoglycan and their overlapping distribution in neuronal synapses. J Cell Biol. 1998 Jul 13; 142(1):139-51.
Hsueh YP, Yang FC, Kharazia V, Naisbitt S, Cohen AR, Weinberg RJ, Sheng M. PMID: 9660869; PMCID: PMC2133027.
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PubMed Mentions:
99 Fields:
Translation:
AnimalsCells
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Differential regional expression and ultrastructural localization of alpha-actinin-2, a putative NMDA receptor-anchoring protein, in rat brain. J Neurosci. 1998 Feb 15; 18(4):1383-92.
Wyszynski M, Kharazia V, Shanghvi R, Rao A, Beggs AH, Craig AM, Weinberg R, Sheng M. PMID: 9454847; PMCID: PMC6792723.
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PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
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Tangential synaptic distribution of NMDA and AMPA receptors in rat neocortex. Neurosci Lett. 1997 Nov 28; 238(1-2):41-4.
Kharazia VN, Weinberg RJ. PMID: 9464650.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Arginine and NADPH diaphorase in the rat ventroposterior thalamic nucleus. Brain Res. 1997 Jan 02; 744(1):151-5.
Kharazia VN, Petrusz P, Usunoff K, Weinberg RJ, Rustioni A. PMID: 9030425.
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PubMed Mentions: Fields:
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AnimalsCells
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Glutamate receptors in spinal motoneurons after sciatic nerve transection. Neuroscience. 1996 Oct; 74(4):953-8.
Popratiloff A, Kharazia VN, Weinberg RJ, Laonipon B, Rustioni A. PMID: 8895864.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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EM colocalization of AMPA and NMDA receptor subunits at synapses in rat cerebral cortex. Neurosci Lett. 1996 May 24; 210(1):37-40.
Kharazia VN, Phend KD, Rustioni A, Weinberg RJ. PMID: 8762186.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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GluR1-immunopositive interneurons in rat neocortex. J Comp Neurol. 1996 May 06; 368(3):399-412.
Kharazia VN, Wenthold RJ, Weinberg RJ. PMID: 8725347.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Glutamate in thalamic fibers terminating in layer IV of primary sensory cortex. J Neurosci. 1994 Oct; 14(10):6021-32.
Kharazia VN, Weinberg RJ. PMID: 7931559; PMCID: PMC6577001.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Type I nitric oxide synthase fully accounts for NADPH-diaphorase in rat striatum, but not cortex. Neuroscience. 1994 Oct; 62(4):983-7.
Kharazia VN, Schmidt HH, Weinberg RJ. PMID: 7531307.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Glutamate in terminals of thalamocortical fibers in rat somatic sensory cortex. Neurosci Lett. 1993 Jul 23; 157(2):162-6.
Kharazia VN, Weinberg RJ. PMID: 7901813.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Neurons in rat cerebral cortex that synthesize nitric oxide: NADPH diaphorase histochemistry, NOS immunocytochemistry, and colocalization with GABA. Neurosci Lett. 1993 Jul 23; 157(2):157-61.
Valtschanoff JG, Weinberg RJ, Kharazia VN, Schmidt HH, Nakane M, Rustioni A. PMID: 7694193.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Neurons in rat hippocampus that synthesize nitric oxide. J Comp Neurol. 1993 May 01; 331(1):111-21.
Valtschanoff JG, Weinberg RJ, Kharazia VN, Nakane M, Schmidt HH. PMID: 7686569.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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[Co-determination of taurine and other free amino acids in the brain during complex immunohistochemical study of the cat and rat somatosensory cortex]. Dokl Akad Nauk. 1992; 324(2):471-4.
Kharaziia VN, Suderevskaia EI, B'erg A, Batuev AS, Rinvik E, Rinvik E, Ottersen DP. PMID: 1360401.
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PubMed Mentions: Fields:
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Animals
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[Research into the problem of central inhibition at the Physiological School of Petersburg-Leningrad University]. Fiziol Zh SSSR Im I M Sechenova. 1991 May; 77(5):115-8.
Batuev AS, Sokolova LV, Kharaziia VN. PMID: 1666374.
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Animals
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The role of inhibitory processes in the formation of functional properties of neurons in vibrissal projection zone of the cat somatosensory cortex. Exp Brain Res. 1989; 76(1):198-206.
Batuev AS, Alexandrov AA, Scheynikov NA, Kcharazia VN, Chan CA. PMID: 2568943.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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[The role of inhibition processes in the development of functional properties of neurons of the vibrissa projection area in the cat somatosensory cortex]. Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Jul-Aug; 37(4):711-9.
Batuev AS, Aleksandrov AA, Shcheinikov NA, Kharaziia VN, Chan TC. PMID: 3673262.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells