Viktor Kharazia • UCSF Profiles

Viktor Kharazia, PhD

Title(s)	Specialist, Physiology
School	School of Medicine
Address	675 Nelson Rising Lane, #535 San Francisco CA 94158
Phone	415-502-7363
vCard	Download vCard

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

High-density single-unit human cortical recordings using the Neuropixels probe. Neuron. 2022 08 03; 110(15):2409-2421.e3. Chung JE, Sellers KK, Leonard MK, Gwilliams L, Xu D, Dougherty ME, Kharazia V, Metzger SL, Welkenhuysen M, Dutta B, Chang EF. PMID: 35679860.

View in: PubMed Mentions: 22 Fields:
Neu Neurology
Translation:Humans Cells
A versatile toolbox for studying cortical physiology in primates. Cell Rep Methods. 2022 03 28; 2(3). Khateeb K, Bloch J, Zhou J, Rahimi M, Griggs DJ, Kharazia VN, Le MN, Wang RK, Yazdan-Shahmorad A. PMID: 35445205; PMCID: PMC9017216.

View in: PubMed Mentions: 4 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Animals
Scalable method for micro-CT analysis enables large scale quantitative characterization of brain lesions and implants. Sci Rep. 2020 11 30; 10(1):20851. Kastner DB, Kharazia V, Nevers R, Smyth C, Astudillo-Maya DA, Williams GM, Yang Z, Holobetz CM, Santina LD, Parkinson DY, Frank LM. PMID: 33257721; PMCID: PMC7705725.

View in: PubMed Mentions: 3 Fields:
Sci Science
Translation:Animals
A Practical Method for Creating Targeted Focal Ischemic Stroke in the Cortex of Nonhuman Primates. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:3515-3518. Khateeb K, Yao Z, Kharazia VN, Burunova EP, Song S, Wang R, Yazdan-Shahmorad A. PMID: 31946636; PMCID: PMC8523301.

View in: PubMed Mentions: 7 Fields:
Bio Biomedical Engineering
Translation:Humans Animals
Targeted cortical reorganization using optogenetics in non-human primates. Elife. 2018 05 29; 7. Yazdan-Shahmorad A, Silversmith DB, Kharazia V, Sabes PN. PMID: 29809133; PMCID: PMC5986269.

View in: PubMed Mentions: 27 Fields:
Bio Biology
Translation:Animals Cells
Widespread optogenetic expression in macaque cortex obtained with MR-guided, convection enhanced delivery (CED) of AAV vector to the thalamus. J Neurosci Methods. 2018 Jan 01; 293:347-358. Yazdan-Shahmorad A, Tian N, Kharazia V, Samaranch L, Kells A, Bringas J, He J, Bankiewicz K, Sabes PN. PMID: 29042259.

View in: PubMed Mentions: 27 Fields:
Neu Neurology
Translation:Animals Cells
Limited Excessive Voluntary Alcohol Drinking Leads to Liver Dysfunction in Mice. Alcohol Clin Exp Res. 2017 02; 41(2):345-358. Wegner SA, Pollard KA, Kharazia V, Darevsky D, Perez L, Roychowdhury S, Xu A, Ron D, Nagy LE, Hopf FW. PMID: 28103636; PMCID: PMC5636002.

View in: PubMed Mentions: 6 Fields:
Sub Substance-Related Disorders
Translation:Animals
A Large-Scale Interface for Optogenetic Stimulation and Recording in Nonhuman Primates. Neuron. 2016 Mar 02; 89(5):927-39. Yazdan-Shahmorad A, Diaz-Botia C, Hanson TL, Kharazia V, Ledochowitsch P, Maharbiz MM, Sabes PN. PMID: 26875625.

View in: PubMed Mentions: 41 Fields:
Neu Neurology
Translation:Animals Cells
A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. Front Neurosci. 2015; 9:487. Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO. PMID: 26733798; PMCID: PMC4689854.

View in: PubMed Mentions: 73
Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption. J Neurochem. 2014 Jun; 129(6):1024-34. Darcq E, Hamida SB, Wu S, Phamluong K, Kharazia V, Xu J, Lombroso P, Ron D. PMID: 24588427; PMCID: PMC4055745.

View in: PubMed Mentions: 22 Fields:
Che Chemistry Neu Neurology
Translation:Animals Cells
Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors. J Neurosci. 2013 Sep 04; 33(36):14369-78. Ben Hamida S, Darcq E, Wang J, Wu S, Phamluong K, Kharazia V, Ron D. PMID: 24005290; PMCID: PMC3761047.

View in: PubMed Mentions: 16 Fields:
Neu Neurology
Translation:Animals Cells
The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area. PLoS One. 2013; 8(7):e68300. Chatterjee S, Santos N, Holgate J, Haass-Koffler CL, Hopf FW, Kharazia V, Lester H, Bonci A, Bartlett SE. PMID: 23869214; PMCID: PMC3712017.

View in: PubMed Mentions: 21 Fields:
Med Medicine (General)Sci Science
Translation:Animals
Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse. Nat Neurosci. 2013 Aug; 16(8):1111-7. Barak S, Liu F, Ben Hamida S, Yowell QV, Neasta J, Kharazia V, Janak PH, Ron D. PMID: 23792945; PMCID: PMC3725202.

View in: PubMed Mentions: 85 Fields:
Neu Neurology
Translation:Animals Cells
The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors. J Neurosci. 2012 Nov 07; 32(45):15849-58. Ben Hamida S, Neasta J, Lasek AW, Kharazia V, Zou M, Carnicella S, Janak PH, Ron D. PMID: 23136424; PMCID: PMC3514017.

View in: PubMed Mentions: 25 Fields:
Neu Neurology
Translation:Animals Cells
Lmo4 in the basolateral complex of the amygdala modulates fear learning. PLoS One. 2012; 7(4):e34559. Maiya R, Kharazia V, Lasek AW, Heberlein U. PMID: 22509321; PMCID: PMC3317997.

View in: PubMed Mentions: 10 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
PKCε phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice. J Clin Invest. 2012 Apr; 122(4):1306-15. Wu DF, Chandra D, McMahon T, Wang D, Dadgar J, Kharazia VN, Liang YJ, Waxman SG, Dib-Hajj SD, Messing RO. PMID: 22426212; PMCID: PMC3315445.

View in: PubMed Mentions: 32 Fields:
Med Medicine (General)
Translation:Animals Cells
Alk is a transcriptional target of LMO4 and ERα that promotes cocaine sensitization and reward. J Neurosci. 2011 Oct 05; 31(40):14134-41. Lasek AW, Gesch J, Giorgetti F, Kharazia V, Heberlein U. PMID: 21976498; PMCID: PMC3197235.

View in: PubMed Mentions: 21 Fields:
Neu Neurology
Translation:Humans Animals Cells
Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system. J Neurosci. 2010 Oct 27; 30(43):14502-12. Wang J, Carnicella S, Ahmadiantehrani S, He DY, Barak S, Kharazia V, Ben Hamida S, Zapata A, Shippenberg TS, Ron D. PMID: 20980608; PMCID: PMC2981598.

View in: PubMed Mentions: 26 Fields:
Neu Neurology
Translation:Humans Animals
Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity. J Neurosci. 2010 Jun 30; 30(26):8830-40. Kapfhamer D, Berger KH, Hopf FW, Seif T, Kharazia V, Bonci A, Heberlein U. PMID: 20592205; PMCID: PMC3842471.

View in: PubMed Mentions: 39 Fields:
Neu Neurology
Translation:Animals Cells
Differential regulation of behavioral tolerance to WIN55,212-2 by GASP1. Neuropsychopharmacology. 2010 May; 35(6):1363-73. Martini L, Thompson D, Kharazia V, Whistler JL. PMID: 20164830; PMCID: PMC2953419.

View in: PubMed Mentions: 25 Fields:
Neu Neurology Psy Psychopharmacology
Translation:Animals Cells
Endogenous BDNF in the dorsolateral striatum gates alcohol drinking. J Neurosci. 2009 Oct 28; 29(43):13494-502. Jeanblanc J, He DY, Carnicella S, Kharazia V, Janak PH, Ron D. PMID: 19864562; PMCID: PMC2855618.

View in: PubMed Mentions: 106 Fields:
Neu Neurology
Translation:Humans Animals Cells
Protein kinase Cdelta regulates ethanol intoxication and enhancement of GABA-stimulated tonic current. J Neurosci. 2008 Nov 12; 28(46):11890-9. Choi DS, Wei W, Deitchman JK, Kharazia VN, Lesscher HM, McMahon T, Wang D, Qi ZH, Sieghart W, Zhang C, Shokat KM, Mody I, Messing RO. PMID: 19005054; PMCID: PMC2688726.

View in: PubMed Mentions: 60 Fields:
Neu Neurology
Translation:Animals Cells
GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. Proc Natl Acad Sci U S A. 2008 Jun 10; 105(23):8114-9. Carnicella S, Kharazia V, Jeanblanc J, Janak PH, Ron D. PMID: 18541917; PMCID: PMC2423415.

View in: PubMed Mentions: 72 Fields:
Sci Science
Translation:Animals Cells PHPublic Health
Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence. Curr Biol. 2008 Jan 22; 18(2):129-35. Kim JA, Bartlett S, He L, Nielsen CK, Chang AM, Kharazia V, Waldhoer M, Ou CJ, Taylor S, Ferwerda M, Cado D, Whistler JL. PMID: 18207746; PMCID: PMC2997702.

View in: PubMed Mentions: 56 Fields:
Bio Biology
Translation:Animals
Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner. J Biol Chem. 2008 Jan 04; 283(1):301-310. Jurd R, Thornton C, Wang J, Luong K, Phamluong K, Kharazia V, Gibb SL, Ron D. PMID: 17962190; PMCID: PMC3124443.

View in: PubMed Mentions: 44 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Acute cocaine exposure alters spine density and long-term potentiation in the ventral tegmental area. Eur J Neurosci. 2007 Aug; 26(3):749-56. Sarti F, Borgland SL, Kharazia VN, Bonci A. PMID: 17686047.

View in: PubMed Mentions: 51 Translation:Animals Cells
Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1. FASEB J. 2007 Mar; 21(3):802-11. Martini L, Waldhoer M, Pusch M, Kharazia V, Fong J, Lee JH, Freissmuth C, Whistler JL. PMID: 17197383.

View in: PubMed Mentions: 65 Fields:
Bio Biology Phy Physiology
Translation:Humans Animals Cells
PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8215-20. Choi DS, Wang D, Yu GQ, Zhu G, Kharazia VN, Paredes JP, Chang WS, Deitchman JK, Mucke L, Messing RO. PMID: 16698938; PMCID: PMC1472455.

View in: PubMed Mentions: 47 Fields:
Sci Science
Translation:Humans Animals Cells
Dopamine responsiveness is regulated by targeted sorting of D2 receptors. Proc Natl Acad Sci U S A. 2005 Aug 09; 102(32):11521-6. Bartlett SE, Enquist J, Hopf FW, Lee JH, Gladher F, Kharazia V, Waldhoer M, Mailliard WS, Armstrong R, Bonci A, Whistler JL. PMID: 16049099; PMCID: PMC1183554.

View in: PubMed Mentions: 88 Fields:
Sci Science
Translation:Humans Animals Cells
RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction. J Neurosci. 2004 Nov 17; 24(46):10542-52. McGough NN, He DY, Logrip ML, Jeanblanc J, Phamluong K, Luong K, Kharazia V, Janak PH, Ron D. PMID: 15548669; PMCID: PMC6730316.

View in: PubMed Mentions: 120 Fields:
Neu Neurology
Translation:Animals Cells
Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury. J Clin Invest. 2004 Jul; 114(1):49-56. Chou WH, Choi DS, Zhang H, Mu D, McMahon T, Kharazia VN, Lowell CA, Ferriero DM, Messing RO. PMID: 15232611; PMCID: PMC437973.

View in: PubMed Mentions: 80 Fields:
Med Medicine (General)
Translation:Animals Cells
Light microscopic study of GluR1 and calbindin expression in interneurons of neocortical microgyral malformations. Neuroscience. 2003; 120(1):207-18. Kharazia VN, Jacobs KM, Prince DA. PMID: 12849753.

View in: PubMed Mentions: 16 Fields:
Neu Neurology
Translation:Animals Cells
A developmental switch of AMPA receptor subunits in neocortical pyramidal neurons. J Neurosci. 2002 Apr 15; 22(8):3005-15. Kumar SS, Bacci A, Kharazia V, Huguenard JR. PMID: 11943803; PMCID: PMC6757523.

View in: PubMed Mentions: 145 Fields:
Neu Neurology
Translation:Animals Cells
Biochemical and morphological characterization of an intracellular membrane compartment containing AMPA receptors. Neuropharmacology. 2001 Nov; 41(6):680-92. Lee SH, Valtschanoff JG, Kharazia VN, Weinberg R, Sheng M. PMID: 11640922.

View in: PubMed Mentions: 28 Fields:
Neu Neurology Pha Pharmacology
Translation:Animals Cells
Changes of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors in layer V of epileptogenic, chronically isolated rat neocortex. Neuroscience. 2001; 102(1):23-34. Kharazia VN, Prince DA. PMID: 11226667.

View in: PubMed Mentions: 3 Fields:
Neu Neurology
Translation:Animals Cells
Postlesional epilepsy: the ultimate brain plasticity. Epilepsia. 2000; 41 Suppl 6:S153-61. Jacobs KM, Graber KD, Kharazia VN, Parada I, Prince DA. PMID: 10999537.

View in: PubMed Mentions: 19 Fields:
Bra Brain Neu Neurology
Translation:Humans Animals Cells
Immunogold localization of AMPA and NMDA receptors in somatic sensory cortex of albino rat. J Comp Neurol. 1999 Sep 20; 412(2):292-302. Kharazia VN, Weinberg RJ. PMID: 10441757.

View in: PubMed Mentions: 78 Fields:
Neu Neurology
Translation:Animals Cells
Mechanisms underlying epileptogenesis in cortical malformations. Epilepsy Res. 1999 Sep; 36(2-3):165-88. Jacobs KM, Kharazia VN, Prince DA. PMID: 10515164.

View in: PubMed Mentions: 38 Fields:
Bra Brain Neu Neurology
Translation:Humans Animals Cells
Tangential synaptic distribution of NMDA and AMPA receptors in rat neocortex. Neurosci Lett. 1997 Nov 28; 238(1-2):41-4. Kharazia VN, Weinberg RJ. PMID: 9464650.

View in: PubMed Mentions: 55 Fields:
Neu Neurology
Translation:Animals Cells
EM colocalization of AMPA and NMDA receptor subunits at synapses in rat cerebral cortex. Neurosci Lett. 1996 May 24; 210(1):37-40. Kharazia VN, Phend KD, Rustioni A, Weinberg RJ. PMID: 8762186.

View in: PubMed Mentions: 28 Fields:
Neu Neurology
Translation:Animals Cells
GluR1-immunopositive interneurons in rat neocortex. J Comp Neurol. 1996 May 06; 368(3):399-412. Kharazia VN, Wenthold RJ, Weinberg RJ. PMID: 8725347.

View in: PubMed Mentions: 11 Fields:
Neu Neurology
Translation:Animals Cells
Glutamate in thalamic fibers terminating in layer IV of primary sensory cortex. J Neurosci. 1994 Oct; 14(10):6021-32. Kharazia VN, Weinberg RJ. PMID: 7931559; PMCID: PMC6577001.

View in: PubMed Mentions: 36 Fields:
Neu Neurology
Translation:Animals Cells