Marta San Luciano Palenzuela, MD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
Address1651 4th Street
San Francisco CA 94158
Phone415-353-2311
ORCID ORCID Icon0000-0002-9885-704X Additional info
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    Collapse Biography 
    Collapse Education and Training
    Albert Einstein College of Medicine, Bronx, NYMS06/2010Clinical Research Methodology
    Beth Israel Medical Center, New York, NY06/2010Movement Disorders
    Boston University School of Medicine, Boston, MA06/2007Neurology
    Metropolitan Hospital, New York, NY06/2004Internal Medicine
    University of Navarre, Pamplona, SpainMD07/2002Medicine
    Collapse Awards and Honors
    American Academy of Neurology2021Elected as Fellow of the American Academy of Neurology
    Hellman Family Foundation2013Award for Early Career Faculty
    American Academy of Neurology2008Clinical Research Training Fellowship

    Collapse Overview 
    Collapse Overview
    Dr. Marta San Luciano specializes in diagnosing and managing movement disorders, including Parkinson's disease, dystonia, tremor and myoclonus, in both children and adults. She has special interests in caring for patients whose genetic background may increase their risk of Parkinson's disease and dystonia, and in developing biomarkers and measuring outcomes, and in medical and especially surgical therapies in movement disorders.

    She received her medical degree from the University of Navarra in Spain and earned a master's degree in clinical research methods from the Albert Einstein College of Medicine. She completed an internship in internal medicine at Metropolitan Hospital Center in New York and a residency in neurology at Boston University Medical Center where she was elected chief resident during her final year. She served as a clinical and research fellow in movement disorders at Beth Israel Deaconess Medical Center in New York.

    She is an active member of the American Academy of Neurology, International Parkinson and Movement Disorder Society and the Parkinson Study Group.

    Her research interests are broadly in clinical and genetic epidemiology of Parkinson's disease, dystonia and other movement disorders and neurodegenerative illnesses, as well as in outcomes research in neuromodulation surgeries for movement disorders. In particular, some of her current research focuses on identifying predictors of favorable motor outcomes following deep brain stimulation surgery in isolated and acquired dystonia, a disabling movement disorder.

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Prefrontal Physiomarkers of Anxiety and Depression in Parkinson's Disease. Front Neurosci. 2021; 15:748165. de Hemptinne C, Chen W, Racine CA, Seritan AL, Miller AM, Yaroshinsky MS, Wang SS, Gilron R, Little S, Bledsoe I, San Luciano M, Katz M, Chang EF, Dawes HE, Ostrem JL, Starr PA. PMID: 34744613; PMCID: PMC8568318.
      View in: PubMed   Mentions: 1  
    2. Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease. Nat Biotechnol. 2021 09; 39(9):1078-1085. Gilron R, Little S, Perrone R, Wilt R, de Hemptinne C, Yaroshinsky MS, Racine CA, Wang SS, Ostrem JL, Larson PS, Wang DD, Galifianakis NB, Bledsoe IO, San Luciano M, Dawes HE, Worrell GA, Kremen V, Borton DA, Denison T, Starr PA. PMID: 33941932; PMCID: PMC8434942.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    3. Thalamic deep brain stimulation for acquired dystonia in children and young adults: a phase 1 clinical trial. J Neurosurg Pediatr. 2020 Nov 27; 27(2):203-212. San Luciano M, Robichaux-Viehoever A, Dodenhoff KA, Gittings ML, Viser AC, Racine CA, Bledsoe IO, Watson Pereira C, Wang SS, Starr PA, Ostrem JL. PMID: 33254134; PMCID: PMC8155109.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    4. Treatment of Dystonia: Medications, Neurotoxins, Neuromodulation, and Rehabilitation. Neurotherapeutics. 2020 10; 17(4):1622-1644. Bledsoe IO, Viser AC, San Luciano M. PMID: 33095402; PMCID: PMC7851280.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Nonsteroidal Anti-inflammatory Use and LRRK2 Parkinson's Disease Penetrance. Mov Disord. 2020 10; 35(10):1755-1764. San Luciano M, Tanner CM, Meng C, Marras C, Goldman SM, Lang AE, Tolosa E, Schüle B, Langston JW, Brice A, Corvol JC, Goldwurm S, Klein C, Brockman S, Berg D, Brockmann K, Ferreira JJ, Tazir M, Mellick GD, Sue CM, Hasegawa K, Tan EK, Bressman S, Saunders-Pullman R, Michael J. Fox Foundation LRRK2 Cohort Consortium. PMID: 32662532; PMCID: PMC7572560.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    6. Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study. Lancet Neurol. 2020 06; 19(6):491-501. Vitek JL, Jain R, Chen L, Tröster AI, Schrock LE, House PA, Giroux ML, Hebb AO, Farris SM, Whiting DM, Leichliter TA, Ostrem JL, San Luciano M, Galifianakis N, Verhagen Metman L, Sani S, Karl JA, Siddiqui MS, Tatter SB, Ul Haq I, Machado AG, Gostkowski M, Tagliati M, Mamelak AN, Okun MS, Foote KD, Moguel-Cobos G, Ponce FA, Pahwa R, Nazzaro JM, Buetefisch CM, Gross RE, Luca CC, Jagid JR, Revuelta GJ, Takacs I, Pourfar MH, Mogilner AY, Duker AP, Mandybur GT, Rosenow JM, Cooper SE, Park MC, Khandhar SM, Sedrak M, Phibbs FT, Pilitsis JG, Uitti RJ, Starr PA. PMID: 32470421.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    7. Phenomenology and Management of Subthalamic Stimulation-Induced Dyskinesia in Patients With Isolated Dystonia. Mov Disord Clin Pract. 2020 Jul; 7(5):548-551. Bledsoe IO, Dodenhoff KA, San Luciano M, Volz MM, Starr PA, Markun LC, Ostrem JL. PMID: 32626800; PMCID: PMC7328432.
      View in: PubMed   Mentions:
    8. Washout of chronic therapeutic deep brain stimulation increases cortical phase-amplitude coupling. Parkinsonism Relat Disord. 2019 09; 66:269-271. Rajagopalan SS, Miller AM, de Hemptinne C, San Luciano M, Ostrem JL, Starr PA. PMID: 31477410; PMCID: PMC7376959.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Patient Experience with Rechargeable Implantable Pulse Generator Deep Brain Stimulation for Movement Disorders. Stereotact Funct Neurosurg. 2019; 97(2):113-119. Mitchell KT, Volz M, Lee A, San Luciano M, Wang S, Starr PA, Larson P, Galifianakis NB, Ostrem JL. PMID: 31288242; PMCID: PMC6689445.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Pallidal Deep-Brain Stimulation Disrupts Pallidal Beta Oscillations and Coherence with Primary Motor Cortex in Parkinson's Disease. J Neurosci. 2018 05 09; 38(19):4556-4568. Wang DD, de Hemptinne C, Miocinovic S, Ostrem JL, Galifianakis NB, San Luciano M, Starr PA. PMID: 29661966; PMCID: PMC5943981.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    11. Before and after the veterans affairs cooperative program 468 study: Deep brain stimulator target selection for treatment of Parkinson's disease. Parkinsonism Relat Disord. 2018 03; 48:40-44. Southwell DG, Rutkowski MJ, San Luciano M, Racine C, Ostrem J, Starr PA, Larson PS. PMID: 29249683.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Sex differences in LRRK2 G2019S and idiopathic Parkinson's Disease. Ann Clin Transl Neurol. 2017 Nov; 4(11):801-810. San Luciano M, Wang C, Ortega RA, Giladi N, Marder K, Bressman S, Saunders-Pullman R, Michael J Fox Foundation LRRK2 Consortium. PMID: 29159192; PMCID: PMC5682117.
      View in: PubMed   Mentions: 8     Fields:    
    13. Parkinson's disease patient preference and experience with various methods of DBS lead placement. Parkinsonism Relat Disord. 2017 Aug; 41:25-30. LaHue SC, Ostrem JL, Galifianakis NB, San Luciano M, Ziman N, Wang S, Racine CA, Starr PA, Larson PS, Katz M. PMID: 28615151.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    14. Subthalamic nucleus deep brain stimulation in isolated dystonia: A 3-year follow-up study. Neurology. 2017 Jan 03; 88(1):25-35. Ostrem JL, San Luciano M, Dodenhoff KA, Ziman N, Markun LC, Racine CA, de Hemptinne C, Volz MM, Heath SL, Starr PA. PMID: 27903810.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    15. Digitized Spiral Drawing: A Possible Biomarker for Early Parkinson's Disease. PLoS One. 2016; 11(10):e0162799. San Luciano M, Wang C, Ortega RA, Yu Q, Boschung S, Soto-Valencia J, Bressman SB, Lipton RB, Pullman S, Saunders-Pullman R. PMID: 27732597; PMCID: PMC5061372.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    16. Gamma Oscillations in the Hyperkinetic State Detected with Chronic Human Brain Recordings in Parkinson's Disease. J Neurosci. 2016 06 15; 36(24):6445-58. Swann NC, de Hemptinne C, Miocinovic S, Qasim S, Wang SS, Ziman N, Ostrem JL, San Luciano M, Galifianakis NB, Starr PA. PMID: 27307233; PMCID: PMC5015781.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    17. Subthalamic local field potentials in Parkinson's disease and isolated dystonia: An evaluation of potential biomarkers. Neurobiol Dis. 2016 May; 89:213-22. Wang DD, de Hemptinne C, Miocinovic S, Qasim SE, Miller AM, Ostrem JL, Galifianakis NB, San Luciano M, Starr PA. PMID: 26884091; PMCID: PMC4790450.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    18. Effective Interventional Magnetic Resonance Image-Guided Laser Ablations in a Parkinson's Disease Patient with Refractory Tremor. Mov Disord Clin Pract. 2016 May-Jun; 3(3):312-314. San Luciano M, Katz M, Ostrem J, Martin A, Starr P, Ziman N, Larson P. PMID: 30713924; PMCID: PMC6353372.
      View in: PubMed   Mentions:
    19. Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease. Nat Neurosci. 2015 May; 18(5):779-86. de Hemptinne C, Swann NC, Ostrem JL, Ryapolova-Webb ES, San Luciano M, Galifianakis NB, Starr PA. PMID: 25867121; PMCID: PMC4414895.
      View in: PubMed   Mentions: 210     Fields:    Translation:Humans
    20. Higher frequency of certain cancers in LRRK2 G2019S mutation carriers with Parkinson disease: a pooled analysis. JAMA Neurol. 2015 Jan; 72(1):58-65. Agalliu I, San Luciano M, Mirelman A, Giladi N, Waro B, Aasly J, Inzelberg R, Hassin-Baer S, Friedman E, Ruiz-Martinez J, Marti-Masso JF, Orr-Urtreger A, Bressman S, Saunders-Pullman R. PMID: 25401981; PMCID: PMC4366130.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    21. Olfactory identification in LRRK2 G2019S mutation carriers: a relevant marker? Ann Clin Transl Neurol. 2014 Sep; 1(9):670-8. Saunders-Pullman R, Mirelman A, Wang C, Alcalay RN, San Luciano M, Ortega R, Raymond D, Mejia-Santana H, Ozelius L, Clark L, Orr-Utreger A, Marder K, Giladi N, Bressman SB. PMID: 25493281; PMCID: PMC4241794.
      View in: PubMed   Mentions: 14     Fields:    
    22. Effect of subthalamic nucleus deep brain stimulation on dual-task cognitive and motor performance in isolated dystonia. J Neurol Neurosurg Psychiatry. 2015 Apr; 86(4):404-9. Mills KA, Markun LC, San Luciano M, Rizk R, Allen IE, Racine CA, Starr PA, Alberts JL, Ostrem JL. PMID: 25012202; PMCID: PMC4392192.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Caregiver burden in epilepsy: determinants and impact. Epilepsy Res Treat. 2014; 2014:808421. Karakis I, Cole AJ, Montouris GD, San Luciano M, Meador KJ, Piperidou C. PMID: 24808956; PMCID: PMC3997889.
      View in: PubMed   Mentions: 17  
    24. Heterogeneity in primary dystonia: lessons from THAP1, GNAL, and TOR1A in Amish-Mennonites. Mov Disord. 2014 May; 29(6):812-8. Saunders-Pullman R, Fuchs T, San Luciano M, Raymond D, Brashear A, Ortega R, Deik A, Ozelius LJ, Bressman SB. PMID: 24500857; PMCID: PMC4013240.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    25. Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations. Mov Disord. 2013 Dec; 28(14):1966-71. Alcalay RN, Mirelman A, Saunders-Pullman R, Tang MX, Mejia Santana H, Raymond D, Roos E, Orbe-Reilly M, Gurevich T, Bar Shira A, Gana Weisz M, Yasinovsky K, Zalis M, Thaler A, Deik A, Barrett MJ, Cabassa J, Groves M, Hunt AL, Lubarr N, San Luciano M, Miravite J, Palmese C, Sachdev R, Sarva H, Severt L, Shanker V, Swan MC, Soto-Valencia J, Johannes B, Ortega R, Fahn S, Cote L, Waters C, Mazzoni P, Ford B, Louis E, Levy O, Rosado L, Ruiz D, Dorovski T, Pauciulo M, Nichols W, Orr-Urtreger A, Ozelius L, Clark L, Giladi N, Bressman S, Marder KS. PMID: 24243757; PMCID: PMC3859844.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    26. Focal task-specific lower extremity dystonia associated with intense repetitive exercise: a case series. Parkinsonism Relat Disord. 2013 Nov; 19(11):1033-8. Katz M, Byl NN, San Luciano M, Ostrem JL. PMID: 23932354.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    27. The utility of routine EEG in the diagnosis of sleep disordered breathing. J Clin Neurophysiol. 2012 Aug; 29(4):333-8. Karakis I, Chiappa KH, San Luciano M, Sassower KC, Stakes JW, Cole AJ. PMID: 22854767.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    28. Variant ataxia-telangiectasia presenting as primary-appearing dystonia in Canadian Mennonites. Neurology. 2012 Feb 28; 78(9):649-57. Saunders-Pullman R, Raymond D, Stoessl AJ, Hobson D, Nakamura K, Nakamura T, Pullman S, Lefton D, Okun MS, Uitti R, Sachdev R, Stanley K, San Luciano M, Hagenah J, Gatti R, Ozelius LJ, Bressman SB. PMID: 22345219; PMCID: PMC3286230.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    29. Gender differences in the IL6 -174G>C and ESR2 1730G>A polymorphisms and the risk of Parkinson's disease. Neurosci Lett. 2012 Jan 11; 506(2):312-6. San Luciano M, Ozelius L, Lipton RB, Raymond D, Bressman SB, Saunders-Pullman R. PMID: 22155094; PMCID: PMC3249002.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    30. Olfactory dysfunction in LRRK2 G2019S mutation carriers. Neurology. 2011 Jul 26; 77(4):319-24. Saunders-Pullman R, Stanley K, Wang C, San Luciano M, Shanker V, Hunt A, Severt L, Raymond D, Ozelius LJ, Lipton RB, Bressman SB. PMID: 21753159; PMCID: PMC3140803.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    31. Gender differences in the risk of familial parkinsonism: beyond LRRK2? Neurosci Lett. 2011 Jun 01; 496(2):125-8. Saunders-Pullman R, Stanley K, San Luciano M, Barrett MJ, Shanker V, Raymond D, Ozelius LJ, Bressman SB. PMID: 21511009; PMCID: PMC3111955.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    32. LRRK2 G2019S mutations may be increased in Puerto Ricans. Mov Disord. 2011 Aug 01; 26(9):1772-3. Saunders-Pullman R, Cabassa J, San Luciano M, Stanley K, Raymond D, Ozelius LJ, Bressman SB. PMID: 21449009; PMCID: PMC3140626.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Clinical expression of LRRK2 G2019S mutations in the elderly. Mov Disord. 2010 Nov 15; 25(15):2571-6. San Luciano M, Lipton RB, Wang C, Katz M, Zimmerman ME, Sanders AE, Ozelius LJ, Bressman SB, Saunders-Pullman R. PMID: 20721910; PMCID: PMC2978804.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    34. Substantia nigra hyperechogenicity in DYT6 dystonia: a pilot study. Parkinsonism Relat Disord. 2010 Jul; 16(6):420-2. Saunders-Pullman R, Stanley K, Brüggemann N, Raymond D, San Luciano M, Wang C, Klein C, Lubarr N, Ozelius L, Bressman SB, Hagenah J. PMID: 20417146; PMCID: PMC2916033.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Clinical and neurophysiological improvement of SGCE myoclonus-dystonia with GPi deep brain stimulation. Clin Neurol Neurosurg. 2010 Feb; 112(2):149-52. Kurtis MM, San Luciano M, Yu Q, Goodman RR, Ford B, Raymond D, Pullman SL, Saunders-Pullman R. PMID: 19896264; PMCID: PMC2815107.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    36. Substance abuse and movement disorders. Curr Drug Abuse Rev. 2009 Sep; 2(3):273-8. San Luciano M, Saunders-Pullman R. PMID: 20443774.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
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