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Basal ganglia theta power indexes trait anxiety in people with Parkinson's disease. Brain. 2024 Oct 21.
Swinnen BEKS, Hoy CW, Pegolo E, Ishihara B, Matzilevich EU, Sun J, Morgante F, Pereira E, Baig F, Hart M, Tan H, Sawacha Z, Beudel M, Wang S, Starr P, Little S, Ricciardi L. PMID: 39432676.
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PubMed Mentions: Fields:
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Sensing data and methodology from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) clinical trial. NPJ Parkinsons Dis. 2024 Sep 17; 10(1):174.
Stanslaski S, Summers RLS, Tonder L, Tan Y, Case M, Raike RS, Morelli N, Herrington TM, Beudel M, Ostrem JL, Little S, Almeida L, Ramirez-Zamora A, Fasano A, Hassell T, Mitchell KT, Moro E, Gostkowski M, Sarangmat N, Bronte-Stewart H, ADAPT-PD Investigators. PMID: 39289373; PMCID: PMC11408616.
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PubMed Mentions:
2
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Chronic adaptive deep brain stimulation versus conventional stimulation in Parkinson's disease: a blinded randomized feasibility trial. Nat Med. 2024 Aug 19.
Oehrn CR, Cernera S, Hammer LH, Shcherbakova M, Yao J, Hahn A, Wang S, Ostrem JL, Little S, Starr PA. PMID: 39160351.
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PubMed Mentions:
5 Fields:
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Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making. Proc Natl Acad Sci U S A. 2024 Jul 30; 121(31):e2322869121.
Hoy CW, de Hemptinne C, Wang SS, Harmer CJ, Apps MAJ, Husain M, Starr PA, Little S. PMID: 39047043; PMCID: PMC11295073.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Interpretable video-based tracking and quantification of parkinsonism clinical motor states. NPJ Parkinsons Dis. 2024 Jun 25; 10(1):122.
Deng D, Ostrem JL, Nguyen V, Cummins DD, Sun J, Pathak A, Little S, Abbasi-Asl R. PMID: 38918385; PMCID: PMC11199701.
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PubMed Mentions:
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Basal ganglia theta power indexes trait anxiety in people with Parkinson's disease. medRxiv. 2024 Jun 05.
Swinnen BEKS, Hoy CW, Pegolo E, Matzilevich EU, Sun J, Ishihara B, Morgante F, Pereira E, Baig F, Hart M, Tan H, Sawacha Z, Beudel M, Wang S, Starr P, Little S, Ricciardi L. PMID: 38883720; PMCID: PMC11177918.
View in:
PubMed Mentions:
1
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Motor network gamma oscillations in chronic home recordings predict dyskinesia in Parkinson's disease. Brain. 2024 Jun 03; 147(6):2038-2052.
Olaru M, Cernera S, Hahn A, Wozny TA, Anso J, de Hemptinne C, Little S, Neumann WJ, Abbasi-Asl R, Starr PA. PMID: 38195196; PMCID: PMC11146421.
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PubMed Mentions: Fields:
Translation:
Humans
-
Neuropsychological and social predictors of participation in a deep brain stimulation study of Parkinson's disease and dystonia. medRxiv. 2024 May 31.
Hahn A, Lazar AA, Cernera S, Little S, Wang SS, Starr PA, Racine CA. PMID: 38854092; PMCID: PMC11160823.
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PubMed Mentions:
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Chronic intracranial recordings in the globus pallidus reveal circadian rhythms in Parkinson's disease. Nat Commun. 2024 May 30; 15(1):4602.
Cagle JN, de Araujo T, Johnson KA, Yu J, Fanty L, Sarmento FP, Little S, Okun MS, Wong JK, de Hemptinne C. PMID: 38816390; PMCID: PMC11139908.
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PubMed Mentions: Fields:
Translation:
Humans
-
Short term cardiovascular symptoms improvement after deep brain stimulation in patients with Parkinson's disease: a systematic review. J Neurol. 2024 Jul; 271(7):3764-3776.
Cucinotta F, Swinnen B, Makovac E, Hirschbichler S, Pereira E, Little S, Morgante F, Ricciardi L. PMID: 38809271; PMCID: PMC11233308.
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PubMed Mentions: Fields:
Translation:
Humans
-
Generalized sleep decoding with basal ganglia signals in multiple movement disorders. NPJ Digit Med. 2024 May 10; 7(1):122.
Yin Z, Yu H, Yuan T, Smyth C, Anjum MF, Zhu G, Ma R, Xu Y, An Q, Gan Y, Merk T, Qin G, Xie H, Zhang N, Wang C, Jiang Y, Meng F, Yang A, Neumann WJ, Starr P, Little S, Li L, Zhang J. PMID: 38729977; PMCID: PMC11087561.
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PubMed Mentions:
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Multi-night cortico-basal recordings reveal mechanisms of NREM slow-wave suppression and spontaneous awakenings in Parkinson's disease. Nat Commun. 2024 Feb 27; 15(1):1793.
Anjum MF, Smyth C, Zuzuárregui R, Dijk DJ, Starr PA, Denison T, Little S. PMID: 38413587; PMCID: PMC10899224.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements. Front Hum Neurosci. 2024; 18:1320806.
Johnson KA, Dosenbach NUF, Gordon EM, Welle CG, Wilkins KB, Bronte-Stewart HM, Voon V, Morishita T, Sakai Y, Merner AR, Lázaro-Muñoz G, Williamson T, Horn A, Gilron R, O'Keeffe J, Gittis AH, Neumann WJ, Little S, Provenza NR, Sheth SA, Fasano A, Holt-Becker AB, Raike RS, Moore L, Pathak YJ, Greene D, Marceglia S, Krinke L, Tan H, Bergman H, Pötter-Nerger M, Sun B, Cabrera LY, McIntyre CC, Harel N, Mayberg HS, Krystal AD, Pouratian N, Starr PA, Foote KD, Okun MS, Wong JK. PMID: 38450221; PMCID: PMC10915873.
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PubMed Mentions:
1
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Towards therapeutic electrophysiological neurofeedback in Parkinson's disease. Parkinsonism Relat Disord. 2024 Apr; 121:106010.
Ubeda Matzilevich E, Daniel PL, Little S. PMID: 38245382.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Beta and theta oscillations track effort and previous reward in human basal ganglia and prefrontal cortex during decision making. bioRxiv. 2023 Dec 06.
Hoy CW, de Hemptinne C, Wang SS, Harmer CJ, Apps MAJ, Husain M, Starr PA, Little S. PMID: 38106063; PMCID: PMC10723308.
View in:
PubMed Mentions:
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Multi-night cortico-basal recordings reveal mechanisms of NREM slow wave suppression and spontaneous awakenings at high-temporal resolution in Parkinson's disease. Res Sq. 2023 Nov 07.
Anjum MF, Smyth C, Dijk DJ, Starr P, Denison T, Little S. PMID: 37986864; PMCID: PMC10659541.
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PubMed Mentions:
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Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson's disease through intracranial recordings. NPJ Parkinsons Dis. 2023 Sep 21; 9(1):136.
Ricciardi L, Apps M, Little S. PMID: 37735477; PMCID: PMC10514046.
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PubMed Mentions:
2
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Sub-harmonic entrainment of cortical gamma oscillations to deep brain stimulation in Parkinson's disease: Model based predictions and validation in three human subjects. Brain Stimul. 2023 Sep-Oct; 16(5):1412-1424.
Sermon JJ, Olaru M, Ansó J, Cernera S, Little S, Shcherbakova M, Bogacz R, Starr PA, Denison T, Duchet B. PMID: 37683763; PMCID: PMC10635843.
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PubMed Mentions:
7 Fields:
Translation:
Humans
-
Adaptive Deep Brain Stimulation for sleep stage targeting in Parkinson's disease. Brain Stimul. 2023 Sep-Oct; 16(5):1292-1296.
Smyth C, Anjum MF, Ravi S, Denison T, Starr P, Little S. PMID: 37567463; PMCID: PMC10835741.
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PubMed Mentions:
9 Fields:
Translation:
Humans
-
Personalized chronic adaptive deep brain stimulation outperforms conventional stimulation in Parkinson's disease. medRxiv. 2023 Aug 08.
Oehrn CR, Cernera S, Hammer LH, Shcherbakova M, Yao J, Hahn A, Wang S, Ostrem JL, Little S, Starr PA. PMID: 37649907; PMCID: PMC10463549.
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PubMed Mentions:
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Bringing the Clinic Home: An At-Home Multi-Modal Data Collection Ecosystem to Support Adaptive Deep Brain Stimulation. J Vis Exp. 2023 07 14; (197).
Strandquist G, Fraczek T, Dixon T, Ravi S, Bechtold R, Lawrence D, Zeng A, Gallant J, Little S, Herron J. PMID: 37522736.
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PubMed Mentions: Fields:
Translation:
Humans
-
Using Neuroscientific and Clinical Context to Assess and Manage Changes in Core Personal Traits Caused by Deep Brain Stimulation. AJOB Neurosci. 2023 Jul-Sep; 14(3):310-312.
Hoy CW, Little SJ, Chiong W. PMID: 37682669; PMCID: PMC10700017.
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PubMed Mentions: Fields:
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Adaptive Deep Brain Stimulation: From Experimental Evidence Toward Practical Implementation. Mov Disord. 2023 06; 38(6):937-948.
Neumann WJ, Gilron R, Little S, Tinkhauser G. PMID: 37148553.
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PubMed Mentions:
13 Fields:
Translation:
Humans
-
High precision magnetoencephalography reveals increased right-inferior frontal gyrus beta power during response conflict. Cortex. 2023 01; 158:127-136.
Daniel PL, Bonaiuto JJ, Bestmann S, Aron AR, Little S. PMID: 36521374; PMCID: PMC9840697.
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PubMed Mentions: Fields:
Translation:
Humans
-
Cortico-Subthalamic Field Potentials Support Classification of the Natural Gait Cycle in Parkinson's Disease and Reveal Individualized Spectral Signatures. eNeuro. 2022 Nov-Dec; 9(6).
Louie KH, Gilron R, Yaroshinsky MS, Morrison MA, Choi J, de Hemptinne C, Little S, Starr PA, Wang DD. PMID: 36270803; PMCID: PMC9663205.
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PubMed Mentions:
5 Fields:
Translation:
Humans
-
Concurrent stimulation and sensing in bi-directional brain interfaces: a multi-site translational experience. J Neural Eng. 2022 03 31; 19(2).
Ansó J, Benjaber M, Parks B, Parker S, Oehrn CR, Petrucci M, Gilron R, Little S, Wilt R, Bronte-Stewart H, Gunduz A, Borton D, Starr PA, Denison T. PMID: 35234664; PMCID: PMC9095704.
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PubMed Mentions:
17 Fields:
Translation:
Humans
-
Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury. Front Hum Neurosci. 2022; 16:813387.
Wong JK, Deuschl G, Wolke R, Bergman H, Muthuraman M, Groppa S, Sheth SA, Bronte-Stewart HM, Wilkins KB, Petrucci MN, Lambert E, Kehnemouyi Y, Starr PA, Little S, Anso J, Gilron R, Poree L, Kalamangalam GP, Worrell GA, Miller KJ, Schiff ND, Butson CR, Henderson JM, Judy JW, Ramirez-Zamora A, Foote KD, Silburn PA, Li L, Oyama G, Kamo H, Sekimoto S, Hattori N, Giordano JJ, DiEuliis D, Shook JR, Doughtery DD, Widge AS, Mayberg HS, Cha J, Choi K, Heisig S, Obatusin M, Opri E, Kaufman SB, Shirvalkar P, Rozell CJ, Alagapan S, Raike RS, Bokil H, Green D, Okun MS. PMID: 35308605; PMCID: PMC8931265.
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PubMed Mentions:
8
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Embedding digital chronotherapy into bioelectronic medicines. iScience. 2022 Apr 15; 25(4):104028.
Fleming JE, Kremen V, Gilron R, Gregg NM, Zamora M, Dijk DJ, Starr PA, Worrell GA, Little S, Denison TJ. PMID: 35313697; PMCID: PMC8933700.
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PubMed Mentions:
11
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Artifact Characterization and a Multipurpose Template-Based Offline Removal Solution for a Sensing-Enabled Deep Brain Stimulation Device. Stereotact Funct Neurosurg. 2022; 100(3):168-183.
Hammer LH, Kochanski RB, Starr PA, Little S. PMID: 35130555; PMCID: PMC9064887.
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PubMed Mentions:
15 Fields:
Translation:
Humans
-
Rapid Dynamic Naturalistic Monitoring of Bradykinesia in Parkinson's Disease Using a Wrist-Worn Accelerometer. Sensors (Basel). 2021 Nov 26; 21(23).
Habets JGV, Herff C, Kubben PL, Kuijf ML, Temel Y, Evers LJW, Bloem BR, Starr PA, Gilron R, Little S. PMID: 34883886; PMCID: PMC8659489.
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PubMed Mentions:
12 Fields:
Translation:
Humans
-
Prefrontal Physiomarkers of Anxiety and Depression in Parkinson's Disease. Front Neurosci. 2021; 15:748165.
de Hemptinne C, Chen W, Racine CA, Seritan AL, Miller AM, Yaroshinsky MS, Wang SS, Gilron R, Little S, Bledsoe I, San Luciano M, Katz M, Chang EF, Dawes HE, Ostrem JL, Starr PA. PMID: 34744613; PMCID: PMC8568318.
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PubMed Mentions:
9
-
Sleep-Aware Adaptive Deep Brain Stimulation Control: Chronic Use at Home With Dual Independent Linear Discriminate Detectors. Front Neurosci. 2021; 15:732499.
Gilron R, Little S, Wilt R, Perrone R, Anso J, Starr PA. PMID: 34733132; PMCID: PMC8558614.
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PubMed Mentions:
18
-
Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci. 2021; 15:765150.
Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS. PMID: 34658825; PMCID: PMC8517517.
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PubMed Mentions:
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The sensitivity of ECG contamination to surgical implantation site in brain computer interfaces. Brain Stimul. 2021 Sep-Oct; 14(5):1301-1306.
Neumann WJ, Memarian Sorkhabi M, Benjaber M, Feldmann LK, Saryyeva A, Krauss JK, Contarino MF, Sieger T, Jech R, Tinkhauser G, Pollo C, Palmisano C, Isaias IU, Cummins DD, Little SJ, Starr PA, Kokkinos V, Gerd-Helge S, Herrington T, Brown P, Richardson RM, Kühn AA, Denison T. PMID: 34428554; PMCID: PMC8460992.
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PubMed Mentions:
19 Fields:
Translation:
Humans
-
Laminar dynamics of high amplitude beta bursts in human motor cortex. Neuroimage. 2021 11 15; 242:118479.
Bonaiuto JJ, Little S, Neymotin SA, Jones SR, Barnes GR, Bestmann S. PMID: 34407440; PMCID: PMC8463839.
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PubMed Mentions:
23 Fields:
Translation:
Humans
-
Chronic Sensing of Subthalamic Local Field Potentials: Comparison of First and Second Generation Implantable Bidirectional Systems Within a Single Subject. Front Neurosci. 2021; 15:725797.
Cummins DD, Kochanski RB, Gilron R, Swann NC, Little S, Hammer LH, Starr PA. PMID: 34447294; PMCID: PMC8382799.
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PubMed Mentions:
14
-
Embedded adaptive deep brain stimulation for cervical dystonia controlled by motor cortex theta oscillations. Exp Neurol. 2021 11; 345:113825.
Johnson V, Wilt R, Gilron R, Anso J, Perrone R, Beudel M, Piña-Fuentes D, Saal J, Ostrem JL, Bledsoe I, Starr P, Little S. PMID: 34331900.
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PubMed Mentions:
13 Fields:
Translation:
Humans
-
Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System. Front Hum Neurosci. 2021; 15:714256.
Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA. PMID: 34322004; PMCID: PMC8312257.
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PubMed Mentions:
13
-
Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease. Nat Biotechnol. 2021 09; 39(9):1078-1085.
Gilron R, Little S, Perrone R, Wilt R, de Hemptinne C, Yaroshinsky MS, Racine CA, Wang SS, Ostrem JL, Larson PS, Wang DD, Galifianakis NB, Bledsoe IO, San Luciano M, Dawes HE, Worrell GA, Kremen V, Borton DA, Denison T, Starr PA. PMID: 33941932; PMCID: PMC8434942.
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PubMed Mentions:
113 Fields:
Translation:
Humans
-
Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci. 2021; 15:644593.
Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS. PMID: 33953663; PMCID: PMC8092047.
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PubMed Mentions:
22
-
The Neurophysiology of Sleep in Parkinson's Disease. Mov Disord. 2021 07; 36(7):1526-1542.
Zahed H, Zuzuarregui JRP, Gilron R, Denison T, Starr PA, Little S. PMID: 33826171.
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PubMed Mentions:
22 Fields:
Translation:
Humans
-
A space-time continuum in DBS: structural and functional advances in Parkinson's disease. Brain. 2021 03 03; 144(2):357-359.
Starr P, Little S. PMID: 33693692.
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PubMed Mentions: Fields:
Translation:
Humans
-
Acute effects of adaptive Deep Brain Stimulation in Parkinson's disease. Brain Stimul. 2020 Nov - Dec; 13(6):1507-1516.
Piña-Fuentes D, van Dijk JMC, van Zijl JC, Moes HR, van Laar T, Oterdoom DLM, Little S, Brown P, Beudel M. PMID: 32738409; PMCID: PMC7116216.
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PubMed Mentions:
22 Fields:
Translation:
Humans
-
Proceedings of the Seventh Annual Deep Brain Stimulation Think Tank: Advances in Neurophysiology, Adaptive DBS, Virtual Reality, Neuroethics and Technology. Front Hum Neurosci. 2020; 14:54.
Ramirez-Zamora A, Giordano J, Gunduz A, Alcantara J, Cagle JN, Cernera S, Difuntorum P, Eisinger RS, Gomez J, Long S, Parks B, Wong JK, Chiu S, Patel B, Grill WM, Walker HC, Little SJ, Gilron R, Tinkhauser G, Thevathasan W, Sinclair NC, Lozano AM, Foltynie T, Fasano A, Sheth SA, Scangos K, Sanger TD, Miller J, Brumback AC, Rajasethupathy P, McIntyre C, Schlachter L, Suthana N, Kubu C, Sankary LR, Herrera-Ferrá K, Goetz S, Cheeran B, Steinke GK, Hess C, Almeida L, Deeb W, Foote KD, Okun MS. PMID: 32292333; PMCID: PMC7134196.
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PubMed Mentions:
17
-
Prefrontal-Subthalamic Hyperdirect Pathway Modulates Movement Inhibition in Humans. Neuron. 2020 05 20; 106(4):579-588.e3.
Chen W, de Hemptinne C, Miller AM, Leibbrand M, Little SJ, Lim DA, Larson PS, Starr PA. PMID: 32155442; PMCID: PMC7274135.
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PubMed Mentions:
77 Fields:
Translation:
Humans
-
Debugging Adaptive Deep Brain Stimulation for Parkinson's Disease. Mov Disord. 2020 04; 35(4):555-561.
Little S, Brown P. PMID: 32039501; PMCID: PMC7166127.
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PubMed Mentions:
38 Fields:
Translation:
Humans
-
Human motor cortical beta bursts relate to movement planning and response errors. PLoS Biol. 2019 10; 17(10):e3000479.
Little S, Bonaiuto J, Barnes G, Bestmann S. PMID: 31584933; PMCID: PMC6795457.
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PubMed Mentions:
58 Fields:
Translation:
Humans
-
Adaptive deep brain stimulation as advanced Parkinson's disease treatment (ADAPT study): protocol for a pseudo-randomised clinical study. BMJ Open. 2019 06 14; 9(6):e029652.
Piña-Fuentes D, Beudel M, Little S, Brown P, Oterdoom DLM, van Dijk JMC. PMID: 31201193; PMCID: PMC6575861.
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PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
-
Phase-Dependent Suppression of Beta Oscillations in Parkinson's Disease Patients. J Neurosci. 2019 02 06; 39(6):1119-1134.
Holt AB, Kormann E, Gulberti A, Pötter-Nerger M, McNamara CG, Cagnan H, Baaske MK, Little S, Köppen JA, Buhmann C, Westphal M, Gerloff C, Engel AK, Brown P, Hamel W, Moll CKE, Sharott A. PMID: 30552179; PMCID: PMC6363933.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
-
The characteristics of pallidal low-frequency and beta bursts could help implementing adaptive brain stimulation in the parkinsonian and dystonic internal globus pallidus. Neurobiol Dis. 2019 01; 121:47-57.
Piña-Fuentes D, van Zijl JC, van Dijk JMC, Little S, Tinkhauser G, Oterdoom DLM, Tijssen MAJ, Beudel M. PMID: 30227227.
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PubMed Mentions:
19 Fields:
Translation:
Humans
-
Toward adaptive deep brain stimulation for dystonia. Neurosurg Focus. 2018 08; 45(2):E3.
Piña-Fuentes D, Beudel M, Little S, van Zijl J, Elting JW, Oterdoom DLM, van Egmond ME, van Dijk JMC, Tijssen MAJ. PMID: 30064317.
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PubMed Mentions:
11 Fields:
Translation:
Humans
-
Parkinsonian Tremor Detection from Subthalamic Nucleus Local Field Potentials for Closed-Loop Deep Brain Stimulation. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:2320-2324.
Shah SA, Tinkhauser G, Chen CC, Little S, Brown P. PMID: 30440871; PMCID: PMC6277049.
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PubMed Mentions:
14 Fields:
Translation:
Humans
-
Alternating Modulation of Subthalamic Nucleus Beta Oscillations during Stepping. J Neurosci. 2018 05 30; 38(22):5111-5121.
Fischer P, Chen CC, Chang YJ, Yeh CH, Pogosyan A, Herz DM, Cheeran B, Green AL, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Hasegawa H, Samuel M, Ashkan K, Brown P, Tan H. PMID: 29760182; PMCID: PMC5977446.
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PubMed Mentions:
39 Fields:
Translation:
Humans
-
Mechanisms Underlying Decision-Making as Revealed by Deep-Brain Stimulation in Patients with Parkinson's Disease. Curr Biol. 2018 04 23; 28(8):1169-1178.e6.
Herz DM, Little S, Pedrosa DJ, Tinkhauser G, Cheeran B, Foltynie T, Bogacz R, Brown P. PMID: 29606416; PMCID: PMC5912902.
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PubMed Mentions:
33 Fields:
Translation:
Humans
-
Adaptive Brain Stimulation for Movement Disorders. Prog Neurol Surg. 2018; 33:230-242.
Beudel M, Cagnan H, Little S. PMID: 29332087.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
Subthalamic nucleus gamma activity increases not only during movement but also during movement inhibition. Elife. 2017 07 25; 6.
Fischer P, Pogosyan A, Herz DM, Cheeran B, Green AL, Fitzgerald J, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Brown P, Tan H. PMID: 28742498; PMCID: PMC5526662.
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PubMed Mentions:
25 Fields:
Translation:
Humans
-
Adaptive DBS in a Parkinson's patient with chronically implanted DBS: A proof of principle. Mov Disord. 2017 08; 32(8):1253-1254.
Piña-Fuentes D, Little S, Oterdoom M, Neal S, Pogosyan A, Tijssen MAJ, van Laar T, Brown P, van Dijk JMC, Beudel M. PMID: 28589687; PMCID: PMC5580798.
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PubMed Mentions:
36 Fields:
Translation:
Humans
-
The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease. Brain. 2017 Apr 01; 140(4):1053-1067.
Tinkhauser G, Pogosyan A, Little S, Beudel M, Herz DM, Tan H, Brown P. PMID: 28334851; PMCID: PMC5382944.
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PubMed Mentions:
164 Fields:
Translation:
Humans
-
Subthalamic nucleus beta and gamma activity is modulated depending on the level of imagined grip force. Exp Neurol. 2017 07; 293:53-61.
Fischer P, Pogosyan A, Cheeran B, Green AL, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Samuel M, Ashkan K, Brown P, Tan H. PMID: 28342747; PMCID: PMC5429975.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Distinct mechanisms mediate speed-accuracy adjustments in cortico-subthalamic networks. Elife. 2017 01 31; 6.
Herz DM, Tan H, Brittain JS, Fischer P, Cheeran B, Green AL, FitzGerald J, Aziz TZ, Ashkan K, Little S, Foltynie T, Limousin P, Zrinzo L, Bogacz R, Brown P. PMID: 28137358; PMCID: PMC5287713.
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39 Fields:
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Stimulating at the right time: phase-specific deep brain stimulation. Brain. 2017 01; 140(1):132-145.
Cagnan H, Pedrosa D, Little S, Pogosyan A, Cheeran B, Aziz T, Green A, Fitzgerald J, Foltynie T, Limousin P, Zrinzo L, Hariz M, Friston KJ, Denison T, Brown P. PMID: 28007997; PMCID: PMC5226063.
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106 Fields:
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Spectral power changes prior to psychogenic non-epileptic seizures: a pilot study. J Neurol Neurosurg Psychiatry. 2017 02; 88(2):190-192.
Meppelink AM, Pareés I, Beudel M, Little S, Yogarajah M, Sisodiya S, Edwards MJ. PMID: 27789542.
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5 Fields:
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Humans
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Adaptive deep brain stimulation for Parkinson's disease demonstrates reduced speech side effects compared to conventional stimulation in the acute setting. J Neurol Neurosurg Psychiatry. 2016 12; 87(12):1388-1389.
Little S, Tripoliti E, Beudel M, Pogosyan A, Cagnan H, Herz D, Bestmann S, Aziz T, Cheeran B, Zrinzo L, Hariz M, Hyam J, Limousin P, Foltynie T, Brown P. PMID: 27530809; PMCID: PMC5136720.
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104 Fields:
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Decisions Made with Less Evidence Involve Higher Levels of Corticosubthalamic Nucleus Theta Band Synchrony. J Cogn Neurosci. 2016 06; 28(6):811-25.
Zavala B, Tan H, Little S, Ashkan K, Green AL, Aziz T, Foltynie T, Zrinzo L, Zaghloul K, Brown P. PMID: 26845109; PMCID: PMC5111088.
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11 Fields:
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Bilateral adaptive deep brain stimulation is effective in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2016 07; 87(7):717-21.
Little S, Beudel M, Zrinzo L, Foltynie T, Limousin P, Hariz M, Neal S, Cheeran B, Cagnan H, Gratwicke J, Aziz TZ, Pogosyan A, Brown P. PMID: 26424898; PMCID: PMC4941128.
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129 Fields:
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Tremor Reduction by Deep Brain Stimulation Is Associated With Gamma Power Suppression in Parkinson's Disease. Neuromodulation. 2015 Jul; 18(5):349-54.
Beudel M, Little S, Pogosyan A, Ashkan K, Foltynie T, Limousin P, Zrinzo L, Hariz M, Bogdanovic M, Cheeran B, Green AL, Aziz T, Thevathasan W, Brown P. PMID: 25879998; PMCID: PMC4829100.
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27 Fields:
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Excessive neural synchrony in Machado-Joseph disease responsive to subthalamic nucleus stimulation. Mov Disord. 2015 Mar; 30(3):437-8.
Anzak A, Little S, Hulse N, Andrews T, Brown P, Samuel M, Ashkan K. PMID: 25689061.
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The nature of tremor circuits in parkinsonian and essential tremor. Brain. 2014 Dec; 137(Pt 12):3223-34.
Cagnan H, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Cheeran B, Fitzgerald J, Green AL, Aziz T, Brown P. PMID: 25200741; PMCID: PMC4240284.
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40 Fields:
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Controlling Parkinson's disease with adaptive deep brain stimulation. J Vis Exp. 2014 Jul 16; (89).
Little S, Pogosyan A, Neal S, Zrinzo L, Hariz M, Foltynie T, Limousin P, Brown P. PMID: 25077449; PMCID: PMC4217393.
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12 Fields:
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Midline frontal cortex low-frequency activity drives subthalamic nucleus oscillations during conflict. J Neurosci. 2014 May 21; 34(21):7322-33.
Zavala BA, Tan H, Little S, Ashkan K, Hariz M, Foltynie T, Zrinzo L, Zaghloul KA, Brown P. PMID: 24849364; PMCID: PMC4028502.
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73 Fields:
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The functional role of beta oscillations in Parkinson's disease. Parkinsonism Relat Disord. 2014 Jan; 20 Suppl 1:S44-8.
Little S, Brown P. PMID: 24262186.
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137 Fields:
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Bilateral functional connectivity of the basal ganglia in patients with Parkinson's disease and its modulation by dopaminergic treatment. PLoS One. 2013; 8(12):e82762.
Little S, Tan H, Anzak A, Pogosyan A, Kühn A, Brown P. PMID: 24376574; PMCID: PMC3869733.
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27 Fields:
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Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation. Brain. 2013 Oct; 136(Pt 10):3062-75.
Cagnan H, Brittain JS, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Joint C, Fitzgerald J, Green AL, Aziz T, Brown P. PMID: 24038075; PMCID: PMC3784287.
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46 Fields:
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Adaptive deep brain stimulation in advanced Parkinson disease. Ann Neurol. 2013 Sep; 74(3):449-57.
Little S, Pogosyan A, Neal S, Zavala B, Zrinzo L, Hariz M, Foltynie T, Limousin P, Ashkan K, FitzGerald J, Green AL, Aziz TZ, Brown P. PMID: 23852650; PMCID: PMC3886292.
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Telemedicine for peer-to-peer psychiatry learning between U.K. and Somaliland medical students. Acad Psychiatry. 2013 May 01; 37(3):182-6.
Keynejad R, Ali FR, Finlayson AE, Handuleh J, Adam G, Bowen JS, Leather A, Little SJ, Whitwell S. PMID: 23632929.
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10 Fields:
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What brain signals are suitable for feedback control of deep brain stimulation in Parkinson's disease? Ann N Y Acad Sci. 2012 Aug; 1265:9-24.
Little S, Brown P. PMID: 22830645; PMCID: PMC3495297.
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A torque-based method demonstrates increased rigidity in Parkinson's disease during low-frequency stimulation. Exp Brain Res. 2012 Jun; 219(4):499-506.
Little S, Joundi RA, Tan H, Pogosyan A, Forrow B, Joint C, Green AL, Aziz TZ, Brown P. PMID: 22580572; PMCID: PMC3366185.
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7 Fields:
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An international, case-based, distance-learning collaboration between the UK and Somaliland using a real-time clinical education website. J Telemed Telecare. 2010; 16(4):181-4.
Finlayson AE, Baraco A, Cronin N, Johnson O, Little S, Nuur A, Tanasie D, Leather A. PMID: 20511568.
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15 Fields:
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Humans