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Simon Little, PhD

Photo of Simon Little, PhD
Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
PronounsHe/Him/His
ORCID ORCID Icon0000-0001-6249-6230 Additional info
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    Title(s)JP Conte Endowed Professor

    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Overview 
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    Dr. Simon Little is a neurologist who specializes in caring for patients with movement disorders, including Parkinson's disease, tremor and dystonia (involuntary muscle contractions that can cause repetitive movements and abnormal posture). He has a particular interest in using deep brain stimulation (surgically implanted electrodes to regulate areas of the brain that trigger abnormal activity) to treat symptoms such as muscle stiffness, slowness and tremors when they haven't responded to other therapies. Similarly, his research focuses on further developing deep brain stimulation therapies to diagnose and treat neurological conditions, including Parkinson's disease.

    Dr Little earned his medical degree at Cambridge University and University College London. Remaining in London, he completed a residency in neurology at St. George's Hospital and the National Hospital for Neurology and Neurosurgery, then returned to University College London as a clinical lecturer in movement disorders and neuroscience. He earned an MRCP(UK) – Membership of the Royal Colleges of Physicians of the United Kingdom for general medicine and also a specialty certificate in neurology. He also a doctorate in experimental neurology from the University of Oxford.

    Collapse Biography 
    Collapse education and training
    Cambridge University, UKMVST2000Medical Sciences
    Cambridge University, UKMA2001Experimental Psychology
    UCL Medical School, UKMBBS2004Clinical Medicine
    Royal College Physicians, UKMRCP2008Clinical Medicine
    Oxford University, UKDPhil2014Experimental Neurology PhD
    Royal College of Physicians, UKCert2016Neurology Speciality Certificate
    USMLE Parts 1 - 3, US2023Clinical Medicine

    Collapse Research 
    Collapse Clinical Trials

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    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Multitarget brain implants enable generalized decoding of Parkinson's disease symptoms from chronic home recordings. Res Sq. 2026 May 15. Neumann WJ, Merk T, Olaru M, Rajamani N, Zvarova P, Purelku E, Yin Z, Köhler R, Vanhoecke J, Oswal A, Zhu G, Zhang J, Abbasi-Asl R, Hahn A, Little S, Horn A, Starr P. PMID: 42183377; PMCID: PMC13193127.
      View in: PubMed   Mentions:
    2. Dynamic neural states underpin motor symptom severity in Parkinson's disease: a longitudinal analysis of chronic cortico-subthalamic nucleus recordings. EBioMedicine. 2026 May 12; 128:106293. Sharma A, Liu T, Abdi-Sargezeh B, Hahn A, Shcherbakova M, Neumann WJ, Little S, Starr P, Oswal A. PMID: 42119302.
      View in: PubMed   Mentions:    Fields:    
    3. Bayesian time-history modeling enhances Parkinsonian motor state classification for adaptive deep brain stimulation. J Neural Eng. 2026 May 12; 23(3). Leung B, Shcherbakova M, Yao J, Cernera S, Oehrn CR, Hahn A, Little S, Starr PA, Hammer LH. PMID: 42013882.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Pre-Beta Burst Dynamics in Parkinson's Disease: Distinguishing Signal from Artifact. Mov Disord. 2026 Apr 17. Abdi-Sargezeh B, Liu T, Sharma A, Denison T, Starr PA, Little S, Litvak V, Oswal A. PMID: 41992817; PMCID: PMC7619083.
      View in: PubMed   Mentions:    Fields:    
    5. Neurochemical drivers of effort: The roles of dopamine and beyond in physical and cognitive exertion. Neurosci Biobehav Rev. 2026 Jul; 186:106696. Periche-Tomas E, Husain M, Apps MAJ, Little S, Harmer CJ. PMID: 42000098.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. On the relationships between apathy, depression and anhedonia. J Neurol Neurosurg Psychiatry. 2026 Mar 27. Zhao S, Ye R, Sen A, Scholl J, Lockwood P, Li M, Karatas KF, Ang YS, Little SJ, Harmer CJ, He K, Li Q, Wang K, Apps MAJ, Manohar S, Husain M. PMID: 41895840.
      View in: PubMed   Mentions:    Fields:    
    7. Stimulation and Medication Effects on Subthalamic Nucleus Beta-Band Power in Parkinson's Disease: Implications for Adaptive Deep Brain Stimulation. Mov Disord. 2026 Mar 11. Hammer LH, Cernera S, Oehrn CR, Yao J, Shcherbakova M, Hahn AG, Little S, Starr PA. PMID: 41810591.
      View in: PubMed   Mentions:    Fields:    
    8. Dopamine Boosts Motivation for Prosocial Effort in Parkinson's Disease. J Neurosci. 2026 Feb 25; 46(8). Talbot J, Cutler J, Tamm M, Little SJ, Harmer CJ, Husain M, Lockwood PL, Apps MAJ. PMID: 39746820; PMCID: PMC12940455.
      View in: PubMed   Mentions: 1     Fields:    
    9. Parkinson's disease as a somato-cognitive action network disorder. Nature. 2026 03; 651(8107):1030-1038. Ren J, Zhang W, Dahmani L, Gordon EM, Li S, Zhou Y, Long Y, Huang J, Zhu Y, Guo N, Jiang C, Zhang F, Bai Y, Wei W, Wu Y, Bush A, Vissani M, Wei L, Oehrn CR, Morrison MA, Zhu Y, Zhang C, Hu Q, Yin Y, Cui W, Fu X, Zhang P, Wang W, Ji GJ, He J, Wang K, Fan D, Wang Z, Kimberley T, Little S, Starr PA, Richardson RM, Li L, Wang M, Wang D, Dosenbach NUF, Liu H. PMID: 41639440; PMCID: PMC13017517.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Personalized supervised and unsupervised intracranial sleep decoding during deep brain stimulation. NPJ Digit Med. 2026 Jan 22. Smyth C, Anjum MF, Zhang JX, Yao J, Abbasi-Asl R, Starr P, Little S. PMID: 41571940.
      View in: PubMed   Mentions:
    11. Cortico-basal oscillations index naturalistic movements during deep brain stimulation. Brain. 2025 Dec 16. Lawrence D, Avraham G, Yao J, Li L, Shi C, Starr PA, Little SJ. PMID: 41399243.
      View in: PubMed   Mentions:    Fields:    
    12. Self-perceived life course sleep duration trajectories and risk and age at onset of Parkinson's disease. NPJ Parkinsons Dis. 2025 Dec 14; 11(1):357. Fang Y, Hardy R, Yaffe K, Little SJ, Tanner CM, Leng Y. PMID: 41392288; PMCID: PMC12738539.
      View in: PubMed   Mentions:
    13. Long-Term Personalized Adaptive Deep Brain Stimulation in Parkinson Disease: A Nonrandomized Clinical Trial. JAMA Neurol. 2025 Nov 01; 82(11):1171-1180. Bronte-Stewart HM, Beudel M, Ostrem JL, Little S, Almeida L, Ramirez-Zamora A, Fasano A, Hassell T, Mitchell KT, Moro E, Gostkowski M, Chattree G, de Bie RMA, de Neeling M, Piña-Fuentes D, Swinnen B, Starr PA, Hammer LH, Foote KD, Richardson RM, Flaherty A, Boogers A, Sa'di Q, Meoni S, Castrioto A, Stanslaski S, Summers RLS, Tonder L, Tan Y, Berrier H, Goble TJ, Raike RS, Herrington TM, ADAPT-PD Investigators. PMID: 40982287; PMCID: PMC12455485.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    14. Prediction of Pathological Subthalamic Nucleus Beta Burst Occurrence in Parkinson's Disease. Mov Disord. 2025 Dec; 40(12):2615-2627. Abdi-Sargezeh B, Shirani S, Sharma A, Liu T, Green A, Akram H, Zrinzo L, Limousin P, Foltynie T, Denison T, Tan H, Litvak V, Little S, Starr PA, Oswal A. PMID: 41041724; PMCID: PMC12710186.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Oscillatory dynamics in isolated dystonia: five hundred hours of chronic invasive multisite motor network recordings. J Neurophysiol. 2025 Aug 01; 134(2):677-690. Cernera S, Shcherbakova M, Hammer LH, Friedrich M, Peach R, Ip CW, Bledsoe I, Little S, Starr PA. PMID: 40720209; PMCID: PMC12659858.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Towards Adaptive Deep Brain Stimulation for Non-Motor Symptoms in Parkinson's Disease? Mov Disord. 2025 Sep; 40(9):1759-1777. Swinnen BEKS, Hoy CW, Little SJ. PMID: 40677143.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Movement-responsive deep brain stimulation for Parkinson's disease using a remotely optimized neural decoder. Nat Biomed Eng. 2026 Jan; 10(1):110-124. Dixon TC, Strandquist G, Zeng A, Fraczek T, Bechtold R, Lawrence D, Ravi S, Starr PA, Gallant JL, Herron JA, Little SJ. PMID: 40579487.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Modeling and optimizing deep brain stimulation to enhance gait in Parkinson's disease: personalized treatment with neurophysiological insights. NPJ Parkinsons Dis. 2025 Jun 18; 11(1):173. Fekri Azgomi H, Louie KH, Bath JE, Presbrey KN, Balakid JP, Marks JH, Wozny TA, Galifianakis NB, San Luciano M, Little S, Starr PA, Wang DD. PMID: 40533464; PMCID: PMC12177069.
      View in: PubMed   Mentions: 2  
    19. Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson's disease. Front Neurosci. 2025; 19:1542493. Presbrey KN, Wozny TA, Louie KH, Little S, Starr PA, Abbasi-Asl R, Wang DD. PMID: 40433500; PMCID: PMC12106502.
      View in: PubMed   Mentions:
    20. Corrigendum: Proceedings of the 12th annual deep brain stimulation think tank: cutting edge technology meets novel applications. Front Hum Neurosci. 2025; 19:1612584. Martinez-Nunez AE, Rozell CJ, Little S, Tan H, Schmidt SL, Grill WM, Pajic M, Turner DA, de Hemptinne C, Machado A, Schiff ND, Holt-Becker AS, Raike RS, Malekmohammadi M, Pathak YJ, Himes L, Greene D, Krinke L, Arlotti M, Rossi L, Robinson J, Bahners BH, Litvak V, Milosevic L, Ghatan S, Schaper FLWVJ, Fox MD, Gregg NM, Kubu C, Jordano JJ, Cascella NG, Nho Y, Halpern CH, Mayberg HS, Choi KS, Song H, Cha J, Alagapan S, Dosenbach NUF, Gordon EM, Ren J, Liu H, Kalia LV, Hescham SA, Kusyk DM, Ramirez-Zamora A, Foote KD, Okun MS, Wong JK. PMID: 40395686; PMCID: PMC12089986.
      View in: PubMed   Mentions:
    21. Will adaptive deep brain stimulation for Parkinson's disease become a real option soon? A Delphi consensus study. NPJ Parkinsons Dis. 2025 May 05; 11(1):110. Guidetti M, Bocci T, De Pedro Del Álamo M, Deuschl G, Fasano A, Martinez-Fernandez R, Gasca-Salas C, Hamani C, Krauss JK, Kühn AA, Limousin P, Little S, Lozano AM, Maiorana NV, Marceglia S, Okun MS, Oliveri S, Ostrem JL, Scelzo E, Schnitzler A, Starr PA, Temel Y, Timmermann L, Tinkhauser G, Visser-Vandewalle V, Volkmann J, Priori A. PMID: 40325017; PMCID: PMC12052990.
      View in: PubMed   Mentions: 3  
    22. Basal ganglia theta power indexes trait anxiety in people with Parkinson's disease. Brain. 2025 Apr 03; 148(4):1228-1241. Swinnen BEKS, Hoy CW, Pegolo E, Ishihara B, Matzilevich EU, Sun J, Morgante F, Pereira E, Baig F, Hart M, Tan H, Sawacha Z, Beudel M, Wang S, Starr P, Little S, Ricciardi L. PMID: 39432676; PMCID: PMC7617510.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Beta Burst Characteristics and Coupling within the Sensorimotor Cortical-Subthalamic Nucleus Circuit Dynamically Relate to Bradykinesia in Parkinson's Disease. Mov Disord. 2025 May; 40(5):962-968. Yao P, Sharma A, Abdi-Sargezeh B, Liu T, Tan H, Hahn A, Starr P, Little S, Oswal A. PMID: 40013548; PMCID: PMC12089894.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Proceedings of the 12th annual deep brain stimulation think tank: cutting edge technology meets novel applications. Front Hum Neurosci. 2025; 19:1544994. Martinez-Nunez AE, Rozell CJ, Little S, Tan H, Schmidt SL, Grill WM, Pajic M, Turner DA, de Hemptinne C, Machado A, Schiff ND, Holt-Becker AS, Raike RS, Malekmohammadi M, Pathak YJ, Himes L, Greene D, Krinke L, Arlotti M, Rossi L, Robinson J, Bahners BH, Litvak V, Milosevic L, Ghatan S, Schaper FLWVJ, Fox MD, Gregg NM, Kubu C, Jordano JJ, Cascella NG, Nho Y, Halpern CH, Mayberg HS, Choi KS, Song H, Cha J, Alagapan S, Dosenbach NUF, Gordon EM, Ren J, Liu H, Kalia LV, Hescham SA, Kusyk DM, Ramirez-Zamora A, Foote KD, Okun MS, Wong JK. PMID: 40070487; PMCID: PMC11893992.
      View in: PubMed   Mentions:
    25. Pitfalls and practical suggestions for using local field potential recordings in DBS clinical practice and research. J Neural Eng. 2025 Feb 06; 22(1). Swinnen BEKS, Buijink AWG, Stam MJ, Hubers D, de Neeling M, Keulen BJ, Morgante F, van Wijk BCM, de Bie RMA, Ricciardi L, Little SJ, Beudel M. PMID: 39870045.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. Deep brain stimulation-entrained gamma oscillations in chronic home recordings in Parkinson's disease. Brain Stimul. 2025 Mar-Apr; 18(2):132-141. Olaru M, Hahn A, Shcherbakova M, Little S, Neumann WJ, Abbasi-Asl R, Starr PA. PMID: 39894343.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. Sustained Clinical Benefit of Adaptive Deep Brain Stimulation in Parkinson's Disease Using Gamma Oscillations: A Case Report. Mov Disord. 2025 Feb; 40(2):345-350. Cernera S, Oehrn CR, Hammer LH, Shcherbakova M, Yao J, Hahn A, Wang S, Ostrem JL, Little S, Starr PA. PMID: 39629629; PMCID: PMC11835528.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    28. Clinically Implemented Sensing-Based Initial Programming of Deep Brain Stimulation for Parkinson's Disease: A Retrospective Study. Neuromodulation. 2025 Apr; 28(3):501-510. Swinnen BEKS, Fuentes A, Volz MM, Heath S, Starr PA, Little SJ, Ostrem JL. PMID: 39625426.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Fluoxetine does not influence response to continuous theta burst stimulation in human motor cortex. Neuropsychopharmacol Rep. 2025 Mar; 45(1):e12493. Austin DK, Amador LMD, Li LM, Little SJ, Rothwell JC. PMID: 39509560; PMCID: PMC11660763.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Modeling and Optimizing Deep Brain Stimulation to Enhance Gait in Parkinson's Disease: Personalized Treatment with Neurophysiological Insights. medRxiv. 2024 Nov 01. Azgomi HF, Louie KH, Bath JE, Presbrey KN, Balakid JP, Marks JH, Wozny TA, Galifianakis NB, Luciano MS, Little S, Starr PA, Wang DD. PMID: 39574845; PMCID: PMC11581078.
      View in: PubMed   Mentions:
    31. Sensing data and methodology from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) clinical trial. NPJ Parkinsons Dis. 2024 Sep 17; 10(1):174. Stanslaski S, Summers RLS, Tonder L, Tan Y, Case M, Raike RS, Morelli N, Herrington TM, Beudel M, Ostrem JL, Little S, Almeida L, Ramirez-Zamora A, Fasano A, Hassell T, Mitchell KT, Moro E, Gostkowski M, Sarangmat N, Bronte-Stewart H, ADAPT-PD Investigators. PMID: 39289373; PMCID: PMC11408616.
      View in: PubMed   Mentions: 33  
    32. Chronic adaptive deep brain stimulation versus conventional stimulation in Parkinson's disease: a blinded randomized feasibility trial. Nat Med. 2024 Nov; 30(11):3345-3356. Oehrn CR, Cernera S, Hammer LH, Shcherbakova M, Yao J, Hahn A, Wang S, Ostrem JL, Little S, Starr PA. PMID: 39160351; PMCID: PMC11826929.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    33. Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making. Proc Natl Acad Sci U S A. 2024 Jul 30; 121(31):e2322869121. Hoy CW, de Hemptinne C, Wang SS, Harmer CJ, Apps MAJ, Husain M, Starr PA, Little S. PMID: 39047043; PMCID: PMC11295073.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    34. Interpretable video-based tracking and quantification of parkinsonism clinical motor states. NPJ Parkinsons Dis. 2024 Jun 25; 10(1):122. Deng D, Ostrem JL, Nguyen V, Cummins DD, Sun J, Pathak A, Little S, Abbasi-Asl R. PMID: 38918385; PMCID: PMC11199701.
      View in: PubMed   Mentions: 7  
    35. Basal ganglia theta power indexes trait anxiety in people with Parkinson's disease. medRxiv. 2024 Jun 05. Swinnen BEKS, Hoy CW, Pegolo E, Matzilevich EU, Sun J, Ishihara B, Morgante F, Pereira E, Baig F, Hart M, Tan H, Sawacha Z, Beudel M, Wang S, Starr P, Little S, Ricciardi L. PMID: 38883720; PMCID: PMC11177918.
      View in: PubMed   Mentions: 1  
    36. Motor network gamma oscillations in chronic home recordings predict dyskinesia in Parkinson's disease. Brain. 2024 Jun 03; 147(6):2038-2052. Olaru M, Cernera S, Hahn A, Wozny TA, Anso J, de Hemptinne C, Little S, Neumann WJ, Abbasi-Asl R, Starr PA. PMID: 38195196; PMCID: PMC11146421.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    37. Neuropsychological and social predictors of participation in a deep brain stimulation study of Parkinson's disease and dystonia. medRxiv. 2024 May 31. Hahn A, Lazar AA, Cernera S, Little S, Wang SS, Starr PA, Racine CA. PMID: 38854092; PMCID: PMC11160823.
      View in: PubMed   Mentions:
    38. Chronic intracranial recordings in the globus pallidus reveal circadian rhythms in Parkinson's disease. Nat Commun. 2024 May 30; 15(1):4602. Cagle JN, de Araujo T, Johnson KA, Yu J, Fanty L, Sarmento FP, Little S, Okun MS, Wong JK, de Hemptinne C. PMID: 38816390; PMCID: PMC11139908.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    39. Short term cardiovascular symptoms improvement after deep brain stimulation in patients with Parkinson's disease: a systematic review. J Neurol. 2024 Jul; 271(7):3764-3776. Cucinotta F, Swinnen B, Makovac E, Hirschbichler S, Pereira E, Little S, Morgante F, Ricciardi L. PMID: 38809271; PMCID: PMC11233308.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Generalized sleep decoding with basal ganglia signals in multiple movement disorders. NPJ Digit Med. 2024 May 10; 7(1):122. Yin Z, Yu H, Yuan T, Smyth C, Anjum MF, Zhu G, Ma R, Xu Y, An Q, Gan Y, Merk T, Qin G, Xie H, Zhang N, Wang C, Jiang Y, Meng F, Yang A, Neumann WJ, Starr P, Little S, Li L, Zhang J. PMID: 38729977; PMCID: PMC11087561.
      View in: PubMed   Mentions: 4  
    41. Multi-night cortico-basal recordings reveal mechanisms of NREM slow-wave suppression and spontaneous awakenings in Parkinson's disease. Nat Commun. 2024 Feb 27; 15(1):1793. Anjum MF, Smyth C, Zuzuárregui R, Dijk DJ, Starr PA, Denison T, Little S. PMID: 38413587; PMCID: PMC10899224.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    42. Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements. Front Hum Neurosci. 2024; 18:1320806. Johnson KA, Dosenbach NUF, Gordon EM, Welle CG, Wilkins KB, Bronte-Stewart HM, Voon V, Morishita T, Sakai Y, Merner AR, Lázaro-Muñoz G, Williamson T, Horn A, Gilron R, O'Keeffe J, Gittis AH, Neumann WJ, Little S, Provenza NR, Sheth SA, Fasano A, Holt-Becker AB, Raike RS, Moore L, Pathak YJ, Greene D, Marceglia S, Krinke L, Tan H, Bergman H, Pötter-Nerger M, Sun B, Cabrera LY, McIntyre CC, Harel N, Mayberg HS, Krystal AD, Pouratian N, Starr PA, Foote KD, Okun MS, Wong JK. PMID: 38450221; PMCID: PMC10915873.
      View in: PubMed   Mentions: 6  
    43. Towards therapeutic electrophysiological neurofeedback in Parkinson's disease. Parkinsonism Relat Disord. 2024 Apr; 121:106010. Ubeda Matzilevich E, Daniel PL, Little S. PMID: 38245382.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    44. Beta and theta oscillations track effort and previous reward in human basal ganglia and prefrontal cortex during decision making. bioRxiv. 2023 Dec 06. Hoy CW, de Hemptinne C, Wang SS, Harmer CJ, Apps MAJ, Husain M, Starr PA, Little S. PMID: 38106063; PMCID: PMC10723308.
      View in: PubMed   Mentions:
    45. Multi-night cortico-basal recordings reveal mechanisms of NREM slow wave suppression and spontaneous awakenings at high-temporal resolution in Parkinson's disease. Res Sq. 2023 Nov 07. Anjum MF, Smyth C, Dijk DJ, Starr P, Denison T, Little S. PMID: 37986864; PMCID: PMC10659541.
      View in: PubMed   Mentions:
    46. Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson's disease through intracranial recordings. NPJ Parkinsons Dis. 2023 Sep 21; 9(1):136. Ricciardi L, Apps M, Little S. PMID: 37735477; PMCID: PMC10514046.
      View in: PubMed   Mentions: 11  
    47. Sub-harmonic entrainment of cortical gamma oscillations to deep brain stimulation in Parkinson's disease: Model based predictions and validation in three human subjects. Brain Stimul. 2023 Sep-Oct; 16(5):1412-1424. Sermon JJ, Olaru M, Ansó J, Cernera S, Little S, Shcherbakova M, Bogacz R, Starr PA, Denison T, Duchet B. PMID: 37683763; PMCID: PMC10635843.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    48. Adaptive Deep Brain Stimulation for sleep stage targeting in Parkinson's disease. Brain Stimul. 2023 Sep-Oct; 16(5):1292-1296. Smyth C, Anjum MF, Ravi S, Denison T, Starr P, Little S. PMID: 37567463; PMCID: PMC10835741.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    49. Personalized chronic adaptive deep brain stimulation outperforms conventional stimulation in Parkinson's disease. medRxiv. 2023 Aug 08. Oehrn CR, Cernera S, Hammer LH, Shcherbakova M, Yao J, Hahn A, Wang S, Ostrem JL, Little S, Starr PA. PMID: 37649907; PMCID: PMC10463549.
      View in: PubMed   Mentions:
    50. Bringing the Clinic Home: An At-Home Multi-Modal Data Collection Ecosystem to Support Adaptive Deep Brain Stimulation. J Vis Exp. 2023 07 14; (197). Strandquist G, Fraczek T, Dixon T, Ravi S, Bechtold R, Lawrence D, Zeng A, Gallant J, Little S, Herron J. PMID: 37522736.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Using Neuroscientific and Clinical Context to Assess and Manage Changes in Core Personal Traits Caused by Deep Brain Stimulation. AJOB Neurosci. 2023 Jul-Sep; 14(3):310-312. Hoy CW, Little SJ, Chiong W. PMID: 37682669; PMCID: PMC10700017.
      View in: PubMed   Mentions:    Fields:    
    52. Adaptive Deep Brain Stimulation: From Experimental Evidence Toward Practical Implementation. Mov Disord. 2023 06; 38(6):937-948. Neumann WJ, Gilron R, Little S, Tinkhauser G. PMID: 37148553.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    53. High precision magnetoencephalography reveals increased right-inferior frontal gyrus beta power during response conflict. Cortex. 2023 01; 158:127-136. Daniel PL, Bonaiuto JJ, Bestmann S, Aron AR, Little S. PMID: 36521374; PMCID: PMC9840697.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    54. Cortico-Subthalamic Field Potentials Support Classification of the Natural Gait Cycle in Parkinson's Disease and Reveal Individualized Spectral Signatures. eNeuro. 2022 Nov-Dec; 9(6). Louie KH, Gilron R, Yaroshinsky MS, Morrison MA, Choi J, de Hemptinne C, Little S, Starr PA, Wang DD. PMID: 36270803; PMCID: PMC9663205.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    55. A Realist Review of How Community-Based Drug Checking Services Could Be Designed and Implemented to Promote Engagement of People Who Use Drugs. Int J Environ Res Public Health. 2022 09 22; 19(19). Masterton W, Falzon D, Burton G, Carver H, Wallace B, Aston EV, Sumnall H, Measham F, Gittins R, Craik V, Schofield J, Little S, Parkes T. PMID: 36231262; PMCID: PMC9564958.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    56. Concurrent stimulation and sensing in bi-directional brain interfaces: a multi-site translational experience. J Neural Eng. 2022 03 31; 19(2). Ansó J, Benjaber M, Parks B, Parker S, Oehrn CR, Petrucci M, Gilron R, Little S, Wilt R, Bronte-Stewart H, Gunduz A, Borton D, Starr PA, Denison T. PMID: 35234664; PMCID: PMC9095704.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    57. Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury. Front Hum Neurosci. 2022; 16:813387. Wong JK, Deuschl G, Wolke R, Bergman H, Muthuraman M, Groppa S, Sheth SA, Bronte-Stewart HM, Wilkins KB, Petrucci MN, Lambert E, Kehnemouyi Y, Starr PA, Little S, Anso J, Gilron R, Poree L, Kalamangalam GP, Worrell GA, Miller KJ, Schiff ND, Butson CR, Henderson JM, Judy JW, Ramirez-Zamora A, Foote KD, Silburn PA, Li L, Oyama G, Kamo H, Sekimoto S, Hattori N, Giordano JJ, DiEuliis D, Shook JR, Doughtery DD, Widge AS, Mayberg HS, Cha J, Choi K, Heisig S, Obatusin M, Opri E, Kaufman SB, Shirvalkar P, Rozell CJ, Alagapan S, Raike RS, Bokil H, Green D, Okun MS. PMID: 35308605; PMCID: PMC8931265.
      View in: PubMed   Mentions: 16  
    58. Embedding digital chronotherapy into bioelectronic medicines. iScience. 2022 Apr 15; 25(4):104028. Fleming JE, Kremen V, Gilron R, Gregg NM, Zamora M, Dijk DJ, Starr PA, Worrell GA, Little S, Denison TJ. PMID: 35313697; PMCID: PMC8933700.
      View in: PubMed   Mentions: 19  
    59. Artifact Characterization and a Multipurpose Template-Based Offline Removal Solution for a Sensing-Enabled Deep Brain Stimulation Device. Stereotact Funct Neurosurg. 2022; 100(3):168-183. Hammer LH, Kochanski RB, Starr PA, Little S. PMID: 35130555; PMCID: PMC9064887.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    60. Rapid Dynamic Naturalistic Monitoring of Bradykinesia in Parkinson's Disease Using a Wrist-Worn Accelerometer. Sensors (Basel). 2021 Nov 26; 21(23). Habets JGV, Herff C, Kubben PL, Kuijf ML, Temel Y, Evers LJW, Bloem BR, Starr PA, Gilron R, Little S. PMID: 34883886; PMCID: PMC8659489.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    61. Prefrontal Physiomarkers of Anxiety and Depression in Parkinson's Disease. Front Neurosci. 2021; 15:748165. de Hemptinne C, Chen W, Racine CA, Seritan AL, Miller AM, Yaroshinsky MS, Wang SS, Gilron R, Little S, Bledsoe I, San Luciano M, Katz M, Chang EF, Dawes HE, Ostrem JL, Starr PA. PMID: 34744613; PMCID: PMC8568318.
      View in: PubMed   Mentions: 10  
    62. Sleep-Aware Adaptive Deep Brain Stimulation Control: Chronic Use at Home With Dual Independent Linear Discriminate Detectors. Front Neurosci. 2021; 15:732499. Gilron R, Little S, Wilt R, Perrone R, Anso J, Starr PA. PMID: 34733132; PMCID: PMC8558614.
      View in: PubMed   Mentions: 34  
    63. Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci. 2021; 15:765150. Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS. PMID: 34658825; PMCID: PMC8517517.
      View in: PubMed   Mentions:
    64. The sensitivity of ECG contamination to surgical implantation site in brain computer interfaces. Brain Stimul. 2021 Sep-Oct; 14(5):1301-1306. Neumann WJ, Memarian Sorkhabi M, Benjaber M, Feldmann LK, Saryyeva A, Krauss JK, Contarino MF, Sieger T, Jech R, Tinkhauser G, Pollo C, Palmisano C, Isaias IU, Cummins DD, Little SJ, Starr PA, Kokkinos V, Gerd-Helge S, Herrington T, Brown P, Richardson RM, Kühn AA, Denison T. PMID: 34428554; PMCID: PMC8460992.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    65. Laminar dynamics of high amplitude beta bursts in human motor cortex. Neuroimage. 2021 11 15; 242:118479. Bonaiuto JJ, Little S, Neymotin SA, Jones SR, Barnes GR, Bestmann S. PMID: 34407440; PMCID: PMC8463839.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    66. Chronic Sensing of Subthalamic Local Field Potentials: Comparison of First and Second Generation Implantable Bidirectional Systems Within a Single Subject. Front Neurosci. 2021; 15:725797. Cummins DD, Kochanski RB, Gilron R, Swann NC, Little S, Hammer LH, Starr PA. PMID: 34447294; PMCID: PMC8382799.
      View in: PubMed   Mentions: 21  
    67. Embedded adaptive deep brain stimulation for cervical dystonia controlled by motor cortex theta oscillations. Exp Neurol. 2021 11; 345:113825. Johnson V, Wilt R, Gilron R, Anso J, Perrone R, Beudel M, Piña-Fuentes D, Saal J, Ostrem JL, Bledsoe I, Starr P, Little S. PMID: 34331900.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    68. Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System. Front Hum Neurosci. 2021; 15:714256. Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA. PMID: 34322004; PMCID: PMC8312257.
      View in: PubMed   Mentions: 22  
    69. Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease. Nat Biotechnol. 2021 09; 39(9):1078-1085. Gilron R, Little S, Perrone R, Wilt R, de Hemptinne C, Yaroshinsky MS, Racine CA, Wang SS, Ostrem JL, Larson PS, Wang DD, Galifianakis NB, Bledsoe IO, San Luciano M, Dawes HE, Worrell GA, Kremen V, Borton DA, Denison T, Starr PA. PMID: 33941932; PMCID: PMC8434942.
      View in: PubMed   Mentions: 157     Fields:    Translation:Humans
    70. Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci. 2021; 15:644593. Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS. PMID: 33953663; PMCID: PMC8092047.
      View in: PubMed   Mentions: 34  
    71. The Neurophysiology of Sleep in Parkinson's Disease. Mov Disord. 2021 07; 36(7):1526-1542. Zahed H, Zuzuarregui JRP, Gilron R, Denison T, Starr PA, Little S. PMID: 33826171.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    72. A space-time continuum in DBS: structural and functional advances in Parkinson's disease. Brain. 2021 03 03; 144(2):357-359. Starr P, Little S. PMID: 33693692.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    73. Acute effects of adaptive Deep Brain Stimulation in Parkinson's disease. Brain Stimul. 2020 Nov - Dec; 13(6):1507-1516. Piña-Fuentes D, van Dijk JMC, van Zijl JC, Moes HR, van Laar T, Oterdoom DLM, Little S, Brown P, Beudel M. PMID: 32738409; PMCID: PMC7116216.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    74. Case report: Headache and neurological deficits with CSF lymphocytosis (HaNDL) associated with P/Q type voltage-gated calcium channel antibodies (CACNA1A). Cephalalgia. 2020 08; 40(9):1003-1007. Adib-Samii P, Little S, Vincent A, Nirmalananthan N. PMID: 32276550.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    75. Glutamatergic Contribution to Probabilistic Reasoning and Jumping to Conclusions in Schizophrenia: A Double-Blind, Randomized Experimental Trial. Biol Psychiatry. 2020 11 01; 88(9):687-697. Strube W, Marshall L, Quattrocchi G, Little S, Cimpianu CL, Ulbrich M, Schneider-Axmann T, Falkai P, Hasan A, Bestmann S. PMID: 32513424.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    76. Proceedings of the Seventh Annual Deep Brain Stimulation Think Tank: Advances in Neurophysiology, Adaptive DBS, Virtual Reality, Neuroethics and Technology. Front Hum Neurosci. 2020; 14:54. Ramirez-Zamora A, Giordano J, Gunduz A, Alcantara J, Cagle JN, Cernera S, Difuntorum P, Eisinger RS, Gomez J, Long S, Parks B, Wong JK, Chiu S, Patel B, Grill WM, Walker HC, Little SJ, Gilron R, Tinkhauser G, Thevathasan W, Sinclair NC, Lozano AM, Foltynie T, Fasano A, Sheth SA, Scangos K, Sanger TD, Miller J, Brumback AC, Rajasethupathy P, McIntyre C, Schlachter L, Suthana N, Kubu C, Sankary LR, Herrera-Ferrá K, Goetz S, Cheeran B, Steinke GK, Hess C, Almeida L, Deeb W, Foote KD, Okun MS. PMID: 32292333; PMCID: PMC7134196.
      View in: PubMed   Mentions: 19  
    77. Prefrontal-Subthalamic Hyperdirect Pathway Modulates Movement Inhibition in Humans. Neuron. 2020 05 20; 106(4):579-588.e3. Chen W, de Hemptinne C, Miller AM, Leibbrand M, Little SJ, Lim DA, Larson PS, Starr PA. PMID: 32155442; PMCID: PMC7274135.
      View in: PubMed   Mentions: 122     Fields:    Translation:Humans
    78. Debugging Adaptive Deep Brain Stimulation for Parkinson's Disease. Mov Disord. 2020 04; 35(4):555-561. Little S, Brown P. PMID: 32039501; PMCID: PMC7166127.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    79. Human motor cortical beta bursts relate to movement planning and response errors. PLoS Biol. 2019 10; 17(10):e3000479. Little S, Bonaiuto J, Barnes G, Bestmann S. PMID: 31584933; PMCID: PMC6795457.
      View in: PubMed   Mentions: 93     Fields:    Translation:Humans
    80. Adaptive deep brain stimulation as advanced Parkinson's disease treatment (ADAPT study): protocol for a pseudo-randomised clinical study. BMJ Open. 2019 06 14; 9(6):e029652. Piña-Fuentes D, Beudel M, Little S, Brown P, Oterdoom DLM, van Dijk JMC. PMID: 31201193; PMCID: PMC6575861.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    81. Phase-Dependent Suppression of Beta Oscillations in Parkinson's Disease Patients. J Neurosci. 2019 02 06; 39(6):1119-1134. Holt AB, Kormann E, Gulberti A, Pötter-Nerger M, McNamara CG, Cagnan H, Baaske MK, Little S, Köppen JA, Buhmann C, Westphal M, Gerloff C, Engel AK, Brown P, Hamel W, Moll CKE, Sharott A. PMID: 30552179; PMCID: PMC6363933.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    82. Lamina-specific cortical dynamics in human visual and sensorimotor cortices. Elife. 2018 10 22; 7. Bonaiuto JJ, Meyer SS, Little S, Rossiter H, Callaghan MF, Dick F, Barnes GR, Bestmann S. PMID: 30346274; PMCID: PMC6197856.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    83. The characteristics of pallidal low-frequency and beta bursts could help implementing adaptive brain stimulation in the parkinsonian and dystonic internal globus pallidus. Neurobiol Dis. 2019 01; 121:47-57. Piña-Fuentes D, van Zijl JC, van Dijk JMC, Little S, Tinkhauser G, Oterdoom DLM, Tijssen MAJ, Beudel M. PMID: 30227227.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    84. Toward adaptive deep brain stimulation for dystonia. Neurosurg Focus. 2018 08; 45(2):E3. Piña-Fuentes D, Beudel M, Little S, van Zijl J, Elting JW, Oterdoom DLM, van Egmond ME, van Dijk JMC, Tijssen MAJ. PMID: 30064317.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    85. Quantifying the performance of MEG source reconstruction using resting state data. Neuroimage. 2018 11 01; 181:453-460. Little S, Bonaiuto J, Meyer SS, Lopez J, Bestmann S, Barnes G. PMID: 30012537; PMCID: PMC6150947.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    86. Parkinsonian Tremor Detection from Subthalamic Nucleus Local Field Potentials for Closed-Loop Deep Brain Stimulation. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:2320-2324. Shah SA, Tinkhauser G, Chen CC, Little S, Brown P. PMID: 30440871; PMCID: PMC6277049.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    87. Alternating Modulation of Subthalamic Nucleus Beta Oscillations during Stepping. J Neurosci. 2018 05 30; 38(22):5111-5121. Fischer P, Chen CC, Chang YJ, Yeh CH, Pogosyan A, Herz DM, Cheeran B, Green AL, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Hasegawa H, Samuel M, Ashkan K, Brown P, Tan H. PMID: 29760182; PMCID: PMC5977446.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    88. Mechanisms Underlying Decision-Making as Revealed by Deep-Brain Stimulation in Patients with Parkinson's Disease. Curr Biol. 2018 04 23; 28(8):1169-1178.e6. Herz DM, Little S, Pedrosa DJ, Tinkhauser G, Cheeran B, Foltynie T, Bogacz R, Brown P. PMID: 29606416; PMCID: PMC5912902.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    89. Adaptive Brain Stimulation for Movement Disorders. Prog Neurol Surg. 2018; 33:230-242. Beudel M, Cagnan H, Little S. PMID: 29332087.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    90. Abnormal beta power is a hallmark of explicit movement control in functional movement disorders. Neurology. 2018 01 16; 90(3):e247-e253. Teodoro T, Meppelink AM, Little S, Grant R, Nielsen G, Macerollo A, Pareés I, Edwards MJ. PMID: 29273688; PMCID: PMC5772156.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    91. Non-invasive laminar inference with MEG: Comparison of methods and source inversion algorithms. Neuroimage. 2018 02 15; 167:372-383. Bonaiuto JJ, Rossiter HE, Meyer SS, Adams N, Little S, Callaghan MF, Dick F, Bestmann S, Barnes GR. PMID: 29203456; PMCID: PMC5862097.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    92. Subthalamic nucleus gamma activity increases not only during movement but also during movement inhibition. Elife. 2017 07 25; 6. Fischer P, Pogosyan A, Herz DM, Cheeran B, Green AL, Fitzgerald J, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Brown P, Tan H. PMID: 28742498; PMCID: PMC5526662.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    93. Adaptive DBS in a Parkinson's patient with chronically implanted DBS: A proof of principle. Mov Disord. 2017 08; 32(8):1253-1254. Piña-Fuentes D, Little S, Oterdoom M, Neal S, Pogosyan A, Tijssen MAJ, van Laar T, Brown P, van Dijk JMC, Beudel M. PMID: 28589687; PMCID: PMC5580798.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    94. The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease. Brain. 2017 Apr 01; 140(4):1053-1067. Tinkhauser G, Pogosyan A, Little S, Beudel M, Herz DM, Tan H, Brown P. PMID: 28334851; PMCID: PMC5382944.
      View in: PubMed   Mentions: 209     Fields:    Translation:Humans
    95. Subthalamic nucleus beta and gamma activity is modulated depending on the level of imagined grip force. Exp Neurol. 2017 07; 293:53-61. Fischer P, Pogosyan A, Cheeran B, Green AL, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Samuel M, Ashkan K, Brown P, Tan H. PMID: 28342747; PMCID: PMC5429975.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    96. Distinct mechanisms mediate speed-accuracy adjustments in cortico-subthalamic networks. Elife. 2017 01 31; 6. Herz DM, Tan H, Brittain JS, Fischer P, Cheeran B, Green AL, FitzGerald J, Aziz TZ, Ashkan K, Little S, Foltynie T, Limousin P, Zrinzo L, Bogacz R, Brown P. PMID: 28137358; PMCID: PMC5287713.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    97. Stimulating at the right time: phase-specific deep brain stimulation. Brain. 2017 01; 140(1):132-145. Cagnan H, Pedrosa D, Little S, Pogosyan A, Cheeran B, Aziz T, Green A, Fitzgerald J, Foltynie T, Limousin P, Zrinzo L, Hariz M, Friston KJ, Denison T, Brown P. PMID: 28007997; PMCID: PMC5226063.
      View in: PubMed   Mentions: 119     Fields:    Translation:Humans
    98. Spectral power changes prior to psychogenic non-epileptic seizures: a pilot study. J Neurol Neurosurg Psychiatry. 2017 02; 88(2):190-192. Meppelink AM, Pareés I, Beudel M, Little S, Yogarajah M, Sisodiya S, Edwards MJ. PMID: 27789542.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    99. Adaptive deep brain stimulation for Parkinson's disease demonstrates reduced speech side effects compared to conventional stimulation in the acute setting. J Neurol Neurosurg Psychiatry. 2016 12; 87(12):1388-1389. Little S, Tripoliti E, Beudel M, Pogosyan A, Cagnan H, Herz D, Bestmann S, Aziz T, Cheeran B, Zrinzo L, Hariz M, Hyam J, Limousin P, Foltynie T, Brown P. PMID: 27530809; PMCID: PMC5136720.
      View in: PubMed   Mentions: 126     Fields:    Translation:Humans
    100. Decisions Made with Less Evidence Involve Higher Levels of Corticosubthalamic Nucleus Theta Band Synchrony. J Cogn Neurosci. 2016 06; 28(6):811-25. Zavala B, Tan H, Little S, Ashkan K, Green AL, Aziz T, Foltynie T, Zrinzo L, Zaghloul K, Brown P. PMID: 26845109; PMCID: PMC5111088.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    101. Computational neurostimulation for Parkinson's disease. Prog Brain Res. 2015; 222:163-90. Little S, Bestmann S. PMID: 26541381.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    102. Bilateral adaptive deep brain stimulation is effective in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2016 07; 87(7):717-21. Little S, Beudel M, Zrinzo L, Foltynie T, Limousin P, Hariz M, Neal S, Cheeran B, Cagnan H, Gratwicke J, Aziz TZ, Pogosyan A, Brown P. PMID: 26424898; PMCID: PMC4941128.
      View in: PubMed   Mentions: 157     Fields:    Translation:Humans
    103. Tremor Reduction by Deep Brain Stimulation Is Associated With Gamma Power Suppression in Parkinson's Disease. Neuromodulation. 2015 Jul; 18(5):349-54. Beudel M, Little S, Pogosyan A, Ashkan K, Foltynie T, Limousin P, Zrinzo L, Hariz M, Bogdanovic M, Cheeran B, Green AL, Aziz T, Thevathasan W, Brown P. PMID: 25879998; PMCID: PMC4829100.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    104. Excessive neural synchrony in Machado-Joseph disease responsive to subthalamic nucleus stimulation. Mov Disord. 2015 Mar; 30(3):437-8. Anzak A, Little S, Hulse N, Andrews T, Brown P, Samuel M, Ashkan K. PMID: 25689061.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    105. The nature of tremor circuits in parkinsonian and essential tremor. Brain. 2014 Dec; 137(Pt 12):3223-34. Cagnan H, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Cheeran B, Fitzgerald J, Green AL, Aziz T, Brown P. PMID: 25200741; PMCID: PMC4240284.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    106. Controlling Parkinson's disease with adaptive deep brain stimulation. J Vis Exp. 2014 Jul 16; (89). Little S, Pogosyan A, Neal S, Zrinzo L, Hariz M, Foltynie T, Limousin P, Brown P. PMID: 25077449; PMCID: PMC4217393.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    107. Midline frontal cortex low-frequency activity drives subthalamic nucleus oscillations during conflict. J Neurosci. 2014 May 21; 34(21):7322-33. Zavala BA, Tan H, Little S, Ashkan K, Hariz M, Foltynie T, Zrinzo L, Zaghloul KA, Brown P. PMID: 24849364; PMCID: PMC4028502.
      View in: PubMed   Mentions: 86     Fields:    Translation:Humans
    108. The functional role of beta oscillations in Parkinson's disease. Parkinsonism Relat Disord. 2014 Jan; 20 Suppl 1:S44-8. Little S, Brown P. PMID: 24262186.
      View in: PubMed   Mentions: 178     Fields:    Translation:Humans
    109. Bilateral functional connectivity of the basal ganglia in patients with Parkinson's disease and its modulation by dopaminergic treatment. PLoS One. 2013; 8(12):e82762. Little S, Tan H, Anzak A, Pogosyan A, Kühn A, Brown P. PMID: 24376574; PMCID: PMC3869733.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    110. Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation. Brain. 2013 Oct; 136(Pt 10):3062-75. Cagnan H, Brittain JS, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Joint C, Fitzgerald J, Green AL, Aziz T, Brown P. PMID: 24038075; PMCID: PMC3784287.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    111. Adaptive deep brain stimulation in advanced Parkinson disease. Ann Neurol. 2013 Sep; 74(3):449-57. Little S, Pogosyan A, Neal S, Zavala B, Zrinzo L, Hariz M, Foltynie T, Limousin P, Ashkan K, FitzGerald J, Green AL, Aziz TZ, Brown P. PMID: 23852650; PMCID: PMC3886292.
      View in: PubMed   Mentions: 552     Fields:    Translation:Humans
    112. Telemedicine for peer-to-peer psychiatry learning between U.K. and Somaliland medical students. Acad Psychiatry. 2013 May 01; 37(3):182-6. Keynejad R, Ali FR, Finlayson AE, Handuleh J, Adam G, Bowen JS, Leather A, Little SJ, Whitwell S. PMID: 23632929.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    113. What brain signals are suitable for feedback control of deep brain stimulation in Parkinson's disease? Ann N Y Acad Sci. 2012 Aug; 1265:9-24. Little S, Brown P. PMID: 22830645; PMCID: PMC3495297.
      View in: PubMed   Mentions: 127     Fields:    Translation:Humans
    114. A torque-based method demonstrates increased rigidity in Parkinson's disease during low-frequency stimulation. Exp Brain Res. 2012 Jun; 219(4):499-506. Little S, Joundi RA, Tan H, Pogosyan A, Forrow B, Joint C, Green AL, Aziz TZ, Brown P. PMID: 22580572; PMCID: PMC3366185.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    115. An international, case-based, distance-learning collaboration between the UK and Somaliland using a real-time clinical education website. J Telemed Telecare. 2010; 16(4):181-4. Finlayson AE, Baraco A, Cronin N, Johnson O, Little S, Nuur A, Tanasie D, Leather A. PMID: 20511568.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
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