Nicholas Galifianakis, MD
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| Title(s) | Associate Professor, Neurology |
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| School | School of Medicine |
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| vCard | Download vCard |
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| Title(s) | UCSF Weill Institute for Neurosciences |
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Biography
| Johns Hopkins University | B.A. | 1997 | |
| Boston University | M.P.H. | 1999 | Public Health/Epidemiology |
| University of Southern California | M.D. | 2003 | School of Medicine |
| University of Southern California | Residency | 2007 | Neurology |
| University of Pennsylvania | Fellowship | 2008 | Parkinson's/Movement Disorders |
| University of California San Francisco | Fellowship | 2009 | Parkinson's/Movement Disorders |
| University of California San Francisco | | 2020 | Diversity, Equity, and Inclusion Champion Training |
Overview
Dr. Nicholas Galifianakis is a neurologist who specializes in taking a comprehensive approach to treating Parkinson's disease, essential tremor, dystonia and other movement disorders. His tools include deep brain stimulation, botulinum toxin injections and medication.
Galifianakis' research interests include outcomes in deep brain stimulation for patients with Parkinson's disease and essential tremor, such as with the use of new interventional MRI techniques. He also is interested in defining types of essential tremor and developing more complete models of care for advanced Parkinson's disease.
Galifianakis earned his medical degree and completed a neurology residency at the University of Southern California, where he served as chief resident. He completed a movement disorders fellowship at the University of Pennsylvania and UCSF.
Galifianakis also sees patients at the Parkinson's Disease Research, Education and Clinical Center in San Francisco, a Veterans Affairs center of excellence. He is a member of the American Academy of Neurology and International Parkinson and Movement Disorder Society.
Bibliographic
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The "Surprise Question" for Prognostication in People with Parkinson's Disease & Related Disorders. J Pain Symptom Manage. 2023 Oct 12.
Mahes A, Macchi ZA, Martin CS, Katz M, Galifianakis NB, Pantilat SZ, Kutner JS, Sillau S, Kluger BM. PMID: 37838080.
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Development and Dissemination of a Neurology Palliative Care Curriculum: Education in Palliative and End-of-Life Care Neurology. Neurol Clin Pract. 2022 Apr; 12(2):176-182.
Kluger BM, Kramer NM, Katz M, Galifianakis NB, Pantilat S, Long J, Vaughan CL, Foster LA, Creutzfeldt CJ, Holloway RG, Sillau S, Hauser J. PMID: 35747891; PMCID: PMC9208408.
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PubMed Mentions:
3
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Prevalence and Cumulative Incidence of Caregiver-Reported Aggression in Advanced Parkinson Disease and Related Disorders. Neurol Clin Pract. 2021 Dec; 11(6):e826-e833.
Macchi ZA, Miyasaki J, Katz M, Galifianakis N, Sillau S, Kluger BM. PMID: 34992965; PMCID: PMC8723973.
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PubMed Mentions:
2
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The TOPAZ study: a home-based trial of zoledronic acid to prevent fractures in neurodegenerative parkinsonism. NPJ Parkinsons Dis. 2021 Mar 01; 7(1):16.
Tanner CM, Cummings SR, Schwarzschild MA, Brown EG, Dorsey ER, Espay AJ, Galifianakis NB, Goldman SM, Litvan I, Luthra N, McFarland NR, Mitchell KT, Standaert DG, Bauer DC, Greenspan SL, Beck JC, Lyles KW. PMID: 33649343; PMCID: PMC7921548.
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PubMed Mentions:
3
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The presence of a caregiver is associated with patient outcomes in patients with Parkinson's disease and atypical parkinsonisms. Parkinsonism Relat Disord. 2020 09; 78:61-65.
Prizer LP, Kluger BM, Sillau S, Katz M, Galifianakis NB, Miyasaki JM. PMID: 32736164.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Medical education in movement disorders during the COVID-19 pandemic. Parkinsonism Relat Disord. 2020 08; 77:11-12.
Zuzuárregui JRP, Bledsoe IO, Brown EG, Dietiker CG, Galifianakis NB. PMID: 32570192; PMCID: PMC7295506.
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PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Predictors of general and health-related quality of life in Parkinson's disease and related disorders including caregiver perspectives. Parkinsonism Relat Disord. 2020 08; 77:5-10.
Trang I, Katz M, Galifianakis N, Fairclough D, Sillau SH, Miyasaki J, Kluger BM. PMID: 32563809.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Remote telemedicine evaluation of deep brain stimulation candidacy: Retrospective cohort analysis. Neurol Clin Pract. 2020 Jun; 10(3):199-205.
Witek N, Heath SL, Ouyang B, Tanner CM, Galifianakis NB. PMID: 32642321; PMCID: PMC7292554.
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PubMed Mentions:
7
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Nonsurgical Management of an Exposed Deep Brain Stimulation Lead. . 2020 Jun 1; 125-128.
Brown BE, Volz VM, Heath HS, Galifianakis GN, Ostrem OJ. .
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Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study. Lancet Neurol. 2020 06; 19(6):491-501.
Vitek JL, Jain R, Chen L, Tröster AI, Schrock LE, House PA, Giroux ML, Hebb AO, Farris SM, Whiting DM, Leichliter TA, Ostrem JL, San Luciano M, Galifianakis N, Verhagen Metman L, Sani S, Karl JA, Siddiqui MS, Tatter SB, Ul Haq I, Machado AG, Gostkowski M, Tagliati M, Mamelak AN, Okun MS, Foote KD, Moguel-Cobos G, Ponce FA, Pahwa R, Nazzaro JM, Buetefisch CM, Gross RE, Luca CC, Jagid JR, Revuelta GJ, Takacs I, Pourfar MH, Mogilner AY, Duker AP, Mandybur GT, Rosenow JM, Cooper SE, Park MC, Khandhar SM, Sedrak M, Phibbs FT, Pilitsis JG, Uitti RJ, Starr PA. PMID: 32470421.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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Comparison of Integrated Outpatient Palliative Care With Standard Care in Patients With Parkinson Disease and Related Disorders: A Randomized Clinical Trial. JAMA Neurol. 2020 05 01; 77(5):551-560.
Kluger BM, Miyasaki J, Katz M, Galifianakis N, Hall K, Pantilat S, Khan R, Friedman C, Cernik W, Goto Y, Long J, Fairclough D, Sillau S, Kutner JS. PMID: 32040141; PMCID: PMC7042842.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Associations between spiritual well-being and quality of life in Parkinson disease. Ann Palliat Med. 2020 05; 9(3):1288-1289.
Miyasaki JM, Kluger BM, Sillau S, Katz M, Galifianakis N, Prizer LP. PMID: 32312061.
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Humans
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Correlates of spiritual wellbeing in persons living with Parkinson disease. Ann Palliat Med. 2020 Feb; 9(Suppl 1):S16-S23.
Prizer LP, Kluger BM, Sillau S, Katz M, Galifianakis N, Miyasaki JM. PMID: 31735039.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Education Research: An experiential outpatient teleneurology curriculum for residents. Neurology. 2019 07 23; 93(4):170-175.
Afshari M, Witek NP, Galifianakis NB. PMID: 31332085.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Patient Experience with Rechargeable Implantable Pulse Generator Deep Brain Stimulation for Movement Disorders. Stereotact Funct Neurosurg. 2019; 97(2):113-119.
Mitchell KT, Volz M, Lee A, San Luciano M, Wang S, Starr PA, Larson P, Galifianakis NB, Ostrem JL. PMID: 31288242; PMCID: PMC6689445.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Does outpatient palliative care improve patient-centered outcomes in Parkinson's disease: Rationale, design, and implementation of a pragmatic comparative effectiveness trial. Contemp Clin Trials. 2019 04; 79:28-36.
Kluger BM, Katz M, Galifianakis N, Pantilat SZ, Kutner JS, Sillau S, Gritz M, Jones J, Fairclough D, Sumrall M, Hall K, Miyasaki J. PMID: 30779960.
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PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
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Practical Implementation Strategies for Outpatient Neurology Palliative Care. Neuropalliative Care. 2019 Jan 1; 293-301.
Galifianakis GN, Katz KM, Kluger KB. .
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Long-Term Outcomes of Bilateral Pallidal Deep Brain Stimulation for X-Linked Dystonia and Parkinsonism. Stereotact Funct Neurosurg. 2018; 96(5):320-326.
Kilbane C, Witt J, Galifianakis NB, Glass GA, Volz M, Heath S, Starr PA, Ostrem JL. PMID: 30481788.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Top Ten Tips Palliative Care Clinicians Should Know About Parkinson's Disease and Related Disorders. J Palliat Med. 2018 10; 21(10):1507-1517.
Katz M, Goto Y, Kluger BM, Galifianakis NB, Miyasaki JM, Kutner JS, Jones CA, Pantilat SZ. PMID: 30204543.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Neuropalliative care: Priorities to move the field forward. Neurology. 2018 07 31; 91(5):217-226.
Creutzfeldt CJ, Kluger B, Kelly AG, Lemmon M, Hwang DY, Galifianakis NB, Carver A, Katz M, Curtis JR, Holloway RG. PMID: 29950434; PMCID: PMC6093769.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Pallidal Deep-Brain Stimulation Disrupts Pallidal Beta Oscillations and Coherence with Primary Motor Cortex in Parkinson's Disease. J Neurosci. 2018 05 09; 38(19):4556-4568.
Wang DD, de Hemptinne C, Miocinovic S, Ostrem JL, Galifianakis NB, San Luciano M, Starr PA. PMID: 29661966; PMCID: PMC5943981.
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PubMed Mentions:
47 Fields:
Translation:
Humans
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Telemedicine Use for Movement Disorders: A Global Survey. Telemed J E Health. 2018 12; 24(12):979-992.
Hassan A, Dorsey ER, Goetz CG, Bloem BR, Guttman M, Tanner CM, Mari Z, Pantelyat A, Galifianakis NB, Bajwa JA, Gatto EM, Cubo E. PMID: 29565764.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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National randomized controlled trial of virtual house calls for Parkinson disease. Neurology. 2017 Sep 12; 89(11):1152-1161.
Beck CA, Beran DB, Biglan KM, Boyd CM, Dorsey ER, Schmidt PN, Simone R, Willis AW, Galifianakis NB, Katz M, Tanner CM, Dodenhoff K, Aldred J, Carter J, Fraser A, Jimenez-Shahed J, Hunter C, Spindler M, Reichwein S, Mari Z, Dunlop B, Morgan JC, McLane D, Hickey P, Gauger L, Richard IH, Mejia NI, Bwala G, Nance M, Shih LC, Singer C, Vargas-Parra S, Zadikoff C, Okon N, Feigin A, Ayan J, Vaughan C, Pahwa R, Dhall R, Hassan A, DeMello S, Riggare SS, Wicks P, Achey MA, Elson MJ, Goldenthal S, Keenan HT, Korn R, Schwarz H, Sharma S, Stevenson EA, Zhu W, Connect.Parkinson Investigators. PMID: 28814455; PMCID: PMC5595275.
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PubMed Mentions:
84 Fields:
Translation:
Humans
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Virtual visits for Parkinson disease: A multicenter noncontrolled cohort. Neurol Clin Pract. 2017 08; 7(4):283-295.
Korn RE, Wagle Shukla A, Katz M, Keenan HT, Goldenthal S, Auinger P, Zhu W, Dodge M, Rizer K, Achey MA, Byrd E, Barbano R, Richard I, Andrzejewski KL, Schwarz HB, Dorsey ER, Biglan KM, Kang G, Kanchana S, Rodriguez R, Tanner CM, Galifianakis NB. PMID: 28840919; PMCID: PMC5566796.
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18
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Parkinson's disease patient preference and experience with various methods of DBS lead placement. Parkinsonism Relat Disord. 2017 Aug; 41:25-30.
LaHue SC, Ostrem JL, Galifianakis NB, San Luciano M, Ziman N, Wang S, Racine CA, Starr PA, Larson PS, Katz M. PMID: 28615151.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Chronic multisite brain recordings from a totally implantable bidirectional neural interface: experience in 5 patients with Parkinson's disease. J Neurosurg. 2018 02; 128(2):605-616.
Swann NC, de Hemptinne C, Miocinovic S, Qasim S, Ostrem JL, Galifianakis NB, Luciano MS, Wang SS, Ziman N, Taylor R, Starr PA. PMID: 28409730; PMCID: PMC5641233.
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PubMed Mentions:
54 Fields:
Translation:
Humans
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Palliative care and Parkinson's disease: Meeting summary and recommendations for clinical research. Parkinsonism Relat Disord. 2017 04; 37:19-26.
Kluger BM, Fox S, Timmons S, Katz M, Galifianakis NB, Subramanian I, Carter JH, Johnson MJ, Richfield EW, Bekelman D, Kutner JS, Miyasaki J. PMID: 28108265.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Problematic Mobile Gaming in Parkinson's Disease: An Impulse Control Disorder for the Smartphone. Mov Disord Clin Pract. 2017 Mar-Apr; 4(2):277-278.
Galifianakis NB, Byrd EA, Ostrem JL, Tanner CM, Racine CA. PMID: 30838269; PMCID: PMC6353464.
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PubMed Mentions:
1
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Gamma Oscillations in the Hyperkinetic State Detected with Chronic Human Brain Recordings in Parkinson's Disease. J Neurosci. 2016 06 15; 36(24):6445-58.
Swann NC, de Hemptinne C, Miocinovic S, Qasim S, Wang SS, Ziman N, Ostrem JL, San Luciano M, Galifianakis NB, Starr PA. PMID: 27307233; PMCID: PMC5015781.
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PubMed Mentions:
107 Fields:
Translation:
Humans
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Innovative approaches in caring for people with Parkinson disease: Filling the gaps. Neurol Clin Pract. 2016 Jun; 6(3):203-205.
Schneider R, Galifianakis NB. PMID: 29443141; PMCID: PMC5727715.
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PubMed Mentions:
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National Randomized Controlled Trial of Virtual House Calls for People with Parkinson's Disease: Interest and Barriers. Telemed J E Health. 2016 07; 22(7):590-8.
Dorsey ER, Achey MA, Beck CA, Beran DB, Biglan KM, Boyd CM, Schmidt PN, Simone R, Willis AW, Galifianakis NB, Katz M, Tanner CM, Dodenhoff K, Ziman N, Aldred J, Carter J, Jimenez-Shahed J, Hunter C, Spindler M, Mari Z, Morgan JC, McLane D, Hickey P, Gauger L, Richard IH, Bull MT, Mejia NI, Bwala G, Nance M, Shih L, Anderson L, Singer C, Zadikoff C, Okon N, Feigin A, Ayan J, Vaughan C, Pahwa R, Cooper J, Webb S, Dhall R, Hassan A, Weis D, DeMello S, Riggare SS, Wicks P, Smith J, Keenan HT, Korn R, Schwarz H, Sharma S, Stevenson EA, Zhu W. PMID: 26886406; PMCID: PMC4939367.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Subthalamic local field potentials in Parkinson's disease and isolated dystonia: An evaluation of potential biomarkers. Neurobiol Dis. 2016 May; 89:213-22.
Wang DD, de Hemptinne C, Miocinovic S, Qasim SE, Miller AM, Ostrem JL, Galifianakis NB, San Luciano M, Starr PA. PMID: 26884091; PMCID: PMC4790450.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Clinical outcomes using ClearPoint interventional MRI for deep brain stimulation lead placement in Parkinson's disease. J Neurosurg. 2016 Apr; 124(4):908-16.
Ostrem JL, Ziman N, Galifianakis NB, Starr PA, Luciano MS, Katz M, Racine CA, Martin AJ, Markun LC, Larson PS. PMID: 26495947.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease. Nat Neurosci. 2015 May; 18(5):779-86.
de Hemptinne C, Swann NC, Ostrem JL, Ryapolova-Webb ES, San Luciano M, Galifianakis NB, Starr PA. PMID: 25867121; PMCID: PMC4414895.
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PubMed Mentions:
235 Fields:
Translation:
Humans
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Sensitive measures of executive dysfunction in non-demented Parkinson's disease. Parkinsonism Relat Disord. 2014 Dec; 20(12):1430-3.
Bott NT, Johnson ET, Schuff N, Galifianakis N, Subas T, Pollock J, Pressman P, Kramer JH, Possin KL. PMID: 25454318; PMCID: PMC4314390.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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203 Application Accuracy of a Second Generation Interventional MRI Stereotactic Platform. Neurosurgery. 2013 Aug 1; 60(&NA;):187.
Larson LP, Starr SP, Ostrem OJ, Galifianakis GN, San Luciano Palenzuela SM, Martin MA. .
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Subthalamic nucleus neurons are synchronized to primary motor cortex local field potentials in Parkinson's disease. J Neurosci. 2013 Apr 24; 33(17):7220-33.
Shimamoto SA, Ryapolova-Webb ES, Ostrem JL, Galifianakis NB, Miller KJ, Starr PA. PMID: 23616531; PMCID: PMC3673303.
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PubMed Mentions:
76 Fields:
Translation:
HumansCells
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Exaggerated phase-amplitude coupling in the primary motor cortex in Parkinson disease. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4780-5.
de Hemptinne C, Ryapolova-Webb ES, Air EL, Garcia PA, Miller KJ, Ojemann JG, Ostrem JL, Galifianakis NB, Starr PA. PMID: 23471992; PMCID: PMC3606991.
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PubMed Mentions:
215 Fields:
Translation:
HumansCTClinical Trials
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Globus pallidus interna deep brain stimulation for tardive dyskinesia: case report and review of the literature. Parkinsonism Relat Disord. 2013 Feb; 19(2):141-7.
Spindler MA, Galifianakis NB, Wilkinson JR, Duda JE. PMID: 23099106.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Clinical outcomes of PD patients having bilateral STN DBS using high-field interventional MR-imaging for lead placement. Clin Neurol Neurosurg. 2013 Jun; 115(6):708-12.
Ostrem JL, Galifianakis NB, Markun LC, Grace JK, Martin AJ, Starr PA, Larson PS. PMID: 22944465; PMCID: PMC3578021.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Multichannel Electromyographic Mapping to Optimize OnabotulinumtoxinA Efficacy in Cervical Dystonia. Tremor Other Hyperkinet Mov (N Y). 2012; 2.
Kilbane C, Ostrem J, Galifianakis N, Grace J, Markun L, Glass GA. PMID: 23439966; PMCID: PMC3569932.
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PubMed Mentions:
2 Fields:
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Multichannel Electromyographic Mapping to Optimize OnabotulinumtoxinA Efficacy in Cervical Dystonia. Tremor and Other Hyperkinetic Movements. 2012 Aug 28; 2(0):02.
Kilbane KC, Ostrem OJ, Galifianakis GN, Grace GJ, Markun ML, Glass GG. .
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Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor. Clin Neurophysiol. 2012 Nov; 123(11):2232-8.
Air EL, Ryapolova-Webb E, de Hemptinne C, Ostrem JL, Galifianakis NB, Larson PS, Chang EF, Starr PA. PMID: 22633916; PMCID: PMC3577937.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Oscillations in sensorimotor cortex in movement disorders: an electrocorticography study. Brain. 2012 Feb; 135(Pt 2):615-30.
Crowell AL, Ryapolova-Webb ES, Ostrem JL, Galifianakis NB, Shimamoto S, Lim DA, Starr PA. PMID: 22252995; PMCID: PMC3281473.
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PubMed Mentions:
77 Fields:
Translation:
HumansCells
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Overview of common movement disorders. Continuum (Minneap Minn). 2010 Feb; 16(1 Movement Disorders):13-48.
Ostrem JL, Galifianakis NB. PMID: 22810179.
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6 Fields:
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Changes in regional brain perfusion during functional brain activation: comparison of [(64)Cu]-PTSM with [(14)C]-Iodoantipyrine. Brain Res. 2008 Oct 09; 1234:32-43.
Holschneider DP, Yang J, Sadler TR, Galifianakis NB, Bozorgzadeh MH, Bading JR, Conti PS, Maarek JM. PMID: 18687316; PMCID: PMC2578839.
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PubMed Mentions:
4 Fields:
Translation:
Animals
This graph shows the total number of publications by year. To see the data as text,
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| Year | Publications |
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| 2008 | 1 |
| 2010 | 1 |
| 2012 | 6 |
| 2013 | 3 |
| 2014 | 1 |
| 2015 | 2 |
| 2016 | 5 |
| 2017 | 5 |
| 2018 | 5 |
| 2019 | 5 |
| 2020 | 8 |
| 2021 | 2 |
| 2022 | 1 |
| 2023 | 1 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
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This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text,
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