Melissa Zimel, MD

Title(s)Associate Professor, Orthopaedic Surgery
SchoolSchool of Medicine
Address1825 4th Street, #L6101
San Francisco CA 94107
Phone415-885-3800
ORCID ORCID Icon0000-0003-0089-3753 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Memorial Sloan Kettering Cancer Center, New York, NY07/2015Orthopaedic Oncology
    William Beaumont Hospital, Royal Oak, MI06/2013Orthopaedic Surgery
    Northwestern University Feinberg School of Medicine, Chicago, ILMD05/2008Medicine
    University of Southern California, Los Angeles, CABA05/2004Biology, Philosophy
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    Melissa Zimel is an Orthopaedic Surgical Oncologist, treating pediatric and adult patients with both benign and malignant bone and soft tissue tumors. She also cares for patients with metastatic disease to the skeleton.

    She serves as the Chair of the Department of Orthopaedic Surgery Diversity Committee and is committed to promoting diversity, equity, and inclusion in healthcare as well as supporting health-care equity and improved health-care access to all people in need.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach. Clin Cancer Res. 2024 02 16; 30(4):849-864. Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MV, Vanderboon EN, Hazard FK, Cho SJ, Avedian RS, Mohler DG, Zimel M, Wustrack R, Curtis C, Sirota M, Sweet-Cordero EA. PMID: 37703185; PMCID: PMC10870121.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Botryomycosis: a rare mimic of sarcoma as an initial presentation of acquired immunodeficiency syndrome. Skeletal Radiol. 2023 Dec 01. Boone SL, Horvai AE, Zimel MN, Brown R, Link TM, McGill KC. PMID: 38036751.
      View in: PubMed   Mentions:    Fields:    
    3. Surgical Site Infection Is Not Associated with 1-Year Progression-Free Survival After Endoprosthetic Reconstruction for Lower-Extremity Osteosarcoma: A Secondary Analysis of PARITY Study Data. J Bone Joint Surg Am. 2023 07 19; 105(Suppl 1):49-56. Jackson KJ, Sullivan CD, Zimel MN, Wustrack RL, PARITY Investigators. PMID: 37466580.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities. bioRxiv. 2023 Jan 20. Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MAV, Vanderboon EN, Hazard FK, Cho SJ, Avedian RS, Mohler DG, Zimel M, Wustrack R, Curtis C, Sirota M, Sweet-Cordero EA. PMID: 36711882; PMCID: PMC9882347.
      View in: PubMed   Mentions:
    5. NCCN Guidelines® Insights: Gastrointestinal Stromal Tumors, Version 2.2022. J Natl Compr Canc Netw. 2022 11; 20(11):1204-1214. von Mehren M, Kane JM, Riedel RF, Sicklick JK, Pollack SM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Poppe M, Schuetze S, Shabason J, Spraker MB, Zimel M, Bergman MA, Sundar H, Hang LE. PMID: 36351335; PMCID: PMC10245542.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    6. Survival and failure modes of the Compress® spindle and expandable distal femur endoprosthesis among pediatric patients: A multi-institutional study. J Surg Oncol. 2023 Jan; 127(1):148-158. Tanaka KS, Andaya VR, Thorpe SW, Gundle KR, Hayden JB, Duong YC, Avedian RS, Mohler DG, Morse LJ, Zimel MN, O'Donnell RJ, Fang A, Randall RL, Tran TH, New C, Wustrack RL, other members of Study Group FORCE. PMID: 36112398; PMCID: PMC10087226.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2022 07; 20(7):815-833. von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA. PMID: 35830886; PMCID: PMC10186762.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    8. Diagnosis and management of pediatric primary bone tumors in the emergency department. Pediatr Emerg Med Pract. 2021 Jul; 18(7):1-20. Nik-Ahd M, Agrawal AK, Zimel M. PMID: 34196516.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Tumor morphology and location associate with immune cell composition in pleomorphic sarcoma. Cancer Immunol Immunother. 2021 Oct; 70(10):3031-3040. Wustrack RL, Shao E, Sheridan J, Zimel M, Cho SJ, Horvai AE, Luong D, Kwek SS, Fong L, Okimoto RA. PMID: 33864502; PMCID: PMC8423706.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    10. NCCN Guidelines Insights: Soft Tissue Sarcoma, Version 1.2021. J Natl Compr Canc Netw. 2020 12 02; 18(12):1604-1612. von Mehren M, Kane JM, Bui MM, Choy E, Connelly M, Dry S, Ganjoo KN, George S, Gonzalez RJ, Heslin MJ, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Meyer C, Pappo AS, Parkes AM, Paz IB, Petersen IA, Poppe M, Riedel RF, Rubin B, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Bergman MA, George GV. PMID: 33285515.
      View in: PubMed   Mentions: 91     Fields:    Translation:Humans
    11. Outcomes of Elderly Patients with Soft Tissue Sarcoma of the Extremities. Int J of Rad Onc Biology Physics. 2020; 6(108). Chew J, Lloyd SA, Okimoto RA, Sabnis A, Nakakura E, Corvera C, Zimel MN, Horvai AE, Cho SJ, Wustrack RL, Braunstein SE.
    12. Fibroma-like perivascular epithelioid cell tumor: a rare case in a long bone. Skeletal Radiol. 2021 Apr; 50(4):821-825. Ramezanpour S, Horvai AE, Zimel M, Bucknor M, Link TM. PMID: 32944815.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Risk of Endoprosthetic Infection and Impact of Health-Related Quality of Life in Patients with Osteosarcoma and Giant Cell Tumor of Bone; a Retrospective Case-Control Study. Ann Joint. 2020; 27(5). Butte Z, Tanaka K, Andaya V, Zimel M, O'Donnell R, Wustrack R. Ann Joint 2020; 5:27. View Publication.
    14. Intraoperative Radiotherapy Without External Beam Radiotherapy in the Management of Primary Soft Tissue Sarcomas of the Extremities. Int J of Rad Onc Biology Physics. 2020; 5(108). Chen WS, Lometti M, Wustrack RL, Zimel MN, O'Donnell RJ, Horvai AE, Cho SJ, Okimoto RA, Jahan TM, Gottschalk AR, Braunstein SE.
    15. Cutibacterium (formerly Propionibacterium) acnes clavicular infection. J Bone Jt Infect. 2019; 4(1):40-49. Zaid M, Chavez MR, Carrasco AE, Zimel MN, Zhang AL, Horvai AE, Link TM, O'Donnell RJ. PMID: 30755847; PMCID: PMC6367193.
      View in: PubMed   Mentions: 4  
    16. A Biomechanical and Structural Comparison of Articular Cartilage and Subchondral Bone of the Glenoid and Humeral Head. Orthop J Sports Med. 2018 Jul; 6(7):2325967118785854. Loy BN, Zimel M, Gowda AL, Tooley TR, Maerz T, Bicos J, Guettler J. PMID: 30046634; PMCID: PMC6055107.
      View in: PubMed   Mentions: 2  
    17. Considerations for the Long Term Treatment of Pediatric Sarcoma Survivors. Indian J Orthop. 2018 Jan-Feb; 52(1):77-80. Weiss KR, Zimel MN. PMID: 29416174; PMCID: PMC5791236.
      View in: PubMed   Mentions: 2  
    18. HPMA-Copolymer Nanocarrier Targets Tumor-Associated Macrophages in Primary and Metastatic Breast Cancer. Mol Cancer Ther. 2017 Dec; 16(12):2701-2710. Zimel MN, Horowitz CB, Rajasekhar VK, Christ AB, Wei X, Wu J, Wojnarowicz PM, Wang D, Goldring SR, Purdue PE, Healey JH. PMID: 28830983; PMCID: PMC5847372.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    19. Galectin-3 in bone tumor microenvironment: a beacon for individual skeletal metastasis management. Cancer Metastasis Rev. 2016 Jun; 35(2):333-46. Nakajima K, Kho DH, Yanagawa T, Zimel M, Heath E, Hogan V, Raz A. PMID: 27067726; PMCID: PMC6859002.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    20. Revision Distal Femoral Arthroplasty With the Compress(®) Prosthesis Has a Low Rate of Mechanical Failure at 10 Years. Clin Orthop Relat Res. 2016 Feb; 474(2):528-36. Zimel MN, Farfalli GL, Zindman AM, Riedel ER, Morris CD, Boland PJ, Healey JH. PMID: 26394638; PMCID: PMC4709327.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    21. Carbon fiber intramedullary nails reduce artifact in postoperative advanced imaging. Skeletal Radiol. 2015 Sep; 44(9):1317-25. Zimel MN, Hwang S, Riedel ER, Healey JH. PMID: 25982252.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    22. Reverse total shoulder arthroplasty for the management of failed shoulder arthroplasty with proximal humeral bone loss: is allograft augmentation necessary? J Shoulder Elbow Surg. 2013 Jun; 22(6):739-44. Budge MD, Moravek JE, Zimel MN, Nolan EM, Wiater JM. PMID: 23021901.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    23. Megaprosthesis versus Condyle-sparing intercalary allograft: distal femoral sarcoma. Clin Orthop Relat Res. 2009 Nov; 467(11):2813-24. Zimel MN, Cizik AM, Rapp TB, Weisstein JS, Conrad EU. PMID: 19662462; PMCID: PMC2758955.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
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