Ruchi Malik, PhD

Title(s)Specialist, Psychiatry
SchoolSchool of Medicine
Address675 Nelson Rising Lane, #401
San Francisco CA 94158
Phone415-502-7377
ORCID ORCID Icon0000-0003-0611-8790 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse education and training
    University of Texas, AustinPostdoc
    National Centre for Biological Sciences, Bangalore, IndiaPhD
    Collapse awards and honors
    2018NARSAD Young Investigator Award, Brain and Behavior Research Foundation
    2011Carl Storm International Diversity Fellowship, Gordon Research Conference
    2010IBRO-SFN travel award

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    Identification of cortical interneuron deficits underlying autism spectrum disorder in Tuberous Sclerosis Complex
    NARSAD, Brain and Behavior Research Foundation P0529703Jan 15, 2019 - Jan 14, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tsc1 Loss in VIP-Lineage Cortical Interneurons Results in More VIP+ Interneurons and Enhanced Excitability. Cells. 2023 12 26; 13(1). Hu JS, Malik R, Sohal VS, Rubenstein JL, Vogt D. PMID: 38201256; PMCID: PMC10777938.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Prefrontal Interneurons: Populations, Pathways, and Plasticity Supporting Typical and Disordered Cognition in Rodent Models. J Neurosci. 2022 11 09; 42(45):8468-8476. Kupferschmidt DA, Cummings KA, Joffe ME, MacAskill A, Malik R, Sánchez-Bellot C, Tejeda HA, Yarur Castillo H. PMID: 36351822; PMCID: PMC9665918.
      View in: PubMed   Mentions: 7     Fields:    
    3. Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition. Cell. 2022 04 28; 185(9):1602-1617.e17. Malik R, Li Y, Schamiloglu S, Sohal VS. PMID: 35487191; PMCID: PMC10027400.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    4. Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition. bioRxiv. 2021. Ruchi Malik, Yi Li, Selin Schamiloglu, Vikaas S. Sohal. View Publication.
    5. Regulatory Elements Inserted into AAVs Confer Preferential Activity in Cortical Interneurons. eNeuro. 2020 Nov/Dec; 7(6). Rubin AN, Malik R, Cho KKA, Lim KJ, Lindtner S, Robinson Schwartz SE, Vogt D, Sohal VS, Rubenstein JLR. PMID: 33199411; PMCID: PMC7768279.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    6. GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons. PLoS One. 2020; 15(6):e0233895. Garst-Orozco J, Malik R, Lanz TA, Weber ML, Xi H, Arion D, Enwright JF, Lewis DA, O'Donnell P, Sohal VS, Buhl DL. PMID: 32497062; PMCID: PMC7272025.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    7. Interneuron Transplantation Rescues Social Behavior Deficits without Restoring Wild-Type Physiology in a Mouse Model of Autism with Excessive Synaptic Inhibition. J Neurosci. 2020 03 11; 40(11):2215-2227. Southwell DG, Seifikar H, Malik R, Lavi K, Vogt D, Rubenstein JL, Sohal VS. PMID: 31988060; PMCID: PMC7083289.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    8. Tsc1 represses parvalbumin expression and fast-spiking properties in somatostatin lineage cortical interneurons. Nat Commun. 2019 11 01; 10(1):4994. Malik R, Pai EL, Rubin AN, Stafford AM, Angara K, Minasi P, Rubenstein JL, Sohal VS, Vogt D. PMID: 31676823; PMCID: PMC6825152.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    9. Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion. Neuron. 2019 06 05; 102(5):944-959.e3. Meda KS, Patel T, Braz JM, Malik R, Turner ML, Seifikar H, Basbaum AI, Sohal VS. PMID: 31030955; PMCID: PMC6554049.
      View in: PubMed   Mentions: 66     Fields:    Translation:Animals
    10. Dendritic GIRK Channels Gate the Integration Window, Plateau Potentials, and Induction of Synaptic Plasticity in Dorsal But Not Ventral CA1 Neurons. J Neurosci. 2017 04 05; 37(14):3940-3955. Malik R, Johnston D. PMID: 28280255; PMCID: PMC5394901.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    11. Transient potassium channels augment degeneracy in hippocampal active dendritic spectral tuning. Sci Rep. 2016 Apr 20; 6:24678. Rathour RK, Malik R, Narayanan R. PMID: 27094086; PMCID: PMC4837398.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    12. Mapping the electrophysiological and morphological properties of CA1 pyramidal neurons along the longitudinal hippocampal axis. Hippocampus. 2016 Mar; 26(3):341-61. Malik R, Dougherty KA, Parikh K, Byrne C, Johnston D. PMID: 26333017; PMCID: PMC4760884.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    13. Enhanced intrinsic excitability and EPSP-spike coupling accompany enriched environment-induced facilitation of LTP in hippocampal CA1 pyramidal neurons. J Neurophysiol. 2012 Mar; 107(5):1366-78. Malik R, Chattarji S. PMID: 22157122.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
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