Sanghee Lee, PhD

Photo of Sanghee Lee, PhD
Title(s)Assistant Researcher, Radiology
SchoolSchool of Medicine
ORCID ORCID Icon0000-0001-8578-9968 Additional info
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    Collapse Biography 
    Collapse education and training
    University of California, San Francisco, United StatesPostdoctoral researcher10/2026Radiology and Biomedical Imaging
    Seoul National University, Republic of KoreaPostdoctoral researcher10/2021Innovative New Drug Convergence Research Center
    Seoul National University, Republic of KoreaPh.D08/2021Radiochemistry and Biomedical Radiation Science
    University of Bari Aldo Moro, ItalyVisiting scholar02/2017
    Gachon University, Republic of KoreaBS02/2014Biomedical Science
    Collapse awards and honors
    World Molecular Imaging Society2026  - 2026Winner of the WMIC 2026 Young Investigator Award
    World Molecular Imaging Society2026  - 2026NIH travel award
    Korea Society of Radiopharmaceuticals and Molecular Probes2018  - 2018Young Investigator Award

    Collapse Research 

    Collapse Featured Content 

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Selective PET imaging of bacterial infection using a glycosylated 18F-fluorodeoxyglucose-derived tracer. Nat Biomed Eng. 2026 Oct 05. Lee SH, Kim JM, López-Álvarez M, Wadhwa A, Bidkar AP, Ur Rahim J, Blecha J, Flavell RR, Ordonez AA, Seo Y, Engel J, Ohliger MA, Wilson DM. PMID: 42834085.
      View in: PubMed   Mentions:
    2. Chemoenzymatic Radiosynthesis of a Gluconate Transporter-Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG. Angew Chem Int Ed Engl. 2026 Aug 11; e8729932. Lee SH, Kim JM, Blecha J, Flavell RR, Ohliger MA, Engel J, Seo Y, Wilson DM. PMID: 42578730.
      View in: PubMed   Mentions:
    3. Discovery of a Thermostable Nigerose Phosphorylase for the Efficient Chemoenzymatic Radiosynthesis of a S. aureus-Targeted 18F-Disaccharide. J Nucl Med. 2026 Aug 03; 67(8):1307-1314. Kim JM, Lee SH, Dhaene S, Ancona A, Kim J, López-Álvarez M, Sorlin AM, Blecha J, Zou W, Neumann KD, Mangiatordi GF, Lee E, Nidetky B, Flavell RR, Seo Y, Engel J, Ohliger MA, Desmet T, Wilson DM. PMID: 42350031; PMCID: PMC13435556.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Detecting Bacteria in Their Mammalian Hosts Using Metabolism-Targeted [13C]CO2 Breath Testing. ACS Cent Sci. 2026 Apr 22; 12(4):457-472. López-Álvarez M, Lee SH, Wadhwa A, Bhat MY, Simmons TS, Kim JM, Bidkar AP, Simpson SR, Dhaene S, Steinberg JD, Blecha J, Flavell RR, McCue MD, Green AM, Sriram R, Desmet T, Engel J, Rosch JW, Ohliger MA, Neumann KD, Wilson DM. PMID: 42038486; PMCID: PMC13107215.
      View in: PubMed   Mentions:
    5. Regioselective Glycosylation of Fluorine-18-Labeled Sorbitol for Enhanced Bacterial Detection In Vivo Using PET. JACS Au. 2025 Dec 22; 5(12):6189-6199. Lee SH, Kim JM, López-Álvarez M, Sorlin AM, Bhat MY, Blecha J, Flavell RR, Seo Y, Engel J, Ohliger M, Wilson DM. PMID: 41450663; PMCID: PMC12728616.
      View in: PubMed   Mentions:
    6. A three-step mitochondria-targeted photodynamic therapy platform integrating TSPO ligands and pH-responsive liposomes. Health Nanotechnology. 2025; 8(1). Sang Hee Lee, Jeong-Seob Lee, Won Chang Lee, Miyeon Jeon, Wooseung Lee, Jongyeong Jeon, Beom Jin Park, Bokyung Kim, Jinyoung Park, Nunzio Denora, Sang Eun Kim, Hyung-Jun Im & Byung Chul Lee. View Publication.
    7. Bioorthogonal Radiolabeling of Azide-Modified Bacteria Using [18F]FB-sulfo-DBCO. Bioconjug Chem. 2024 04 17; 35(4):517-527. Alanizi AA, Sorlin AM, Parker MFL, López-Álvarez M, Qin H, Lee SH, Blecha J, Rosenberg OS, Engel J, Ohliger MA, Flavell RR, Wilson DM. PMID: 38482815; PMCID: PMC11036355.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Peptidoglycan-Targeted [18F]3,3,3-Trifluoro-d-alanine Tracer for Imaging Bacterial Infection. JACS Au. 2024 Mar 25; 4(3):1039-1047. Sorlin AM, López-Álvarez M, Biboy J, Gray J, Rabbitt SJ, Rahim JU, Lee SH, Bobba KN, Blecha J, Parker MFL, Flavell RR, Engel J, Ohliger M, Vollmer W, Wilson DM. PMID: 38559735; PMCID: PMC10976610.
      View in: PubMed   Mentions: 4  
    9. Radiosynthesis and whole-body distribution in mice of a 18 F-labeled azepino[4,3-b]indole-1-one derivative with multimodal activity for the treatment of Alzheimer's disease. Arch Pharm (Weinheim). 2024 Mar; 357(3):e2300491. Lee SH, Purgatorio R, Samarelli F, Catto M, Denora N, Morgese MG, Tucci P, Trabace L, Kim HW, Park HS, Kim SE, Lee BC, de Candia M, Altomare CD. PMID: 38158335.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    10. Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography Radiotracers. ACS Sens. 2023 12 22; 8(12):4554-4565. Lee SH, Kim JM, López-Álvarez M, Wang C, Sorlin AM, Bobba KN, Pichardo-González PA, Blecha J, Seo Y, Flavell RR, Engel J, Ohliger MA, Wilson DM. PMID: 37992233; PMCID: PMC10749472.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    11. Evaluating the Performance of Pathogen-Targeted Positron Emission Tomography Radiotracers in a Rat Model of Vertebral Discitis-Osteomyelitis. J Infect Dis. 2023 10 03; 228(Suppl 4):S281-S290. Parker MFL, López-Álvarez M, Alanizi AA, Luu JM, Polvoy I, Sorlin AM, Qin H, Lee S, Rabbitt SJ, Pichardo-González PA, Ordonez AA, Blecha J, Rosenberg OS, Flavell RR, Engel J, Jain SK, Ohliger MA, Wilson DM. PMID: 37788505; PMCID: PMC11009497.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    12. Designing novel anticancer sulfonamide based 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential carbonic anhydrase inhibitor. Journal of Molecular Structure. 2021; 1246:131145. Mujahid Abas, Ali Bahadur, Zaman Ashraf, Shahid Iqbal, Muhammad Shahid Riaz Rajoka, S.G. Rashid, Erum Jabeen, Zafar Iqbal, Qamar Abbas, Abdul Bais, Mubashir Hassan, Guocong Liu, Kejun Feng, Sanghee Lee, Muhammad Nawaz, Muhammad Abdul Qayyum. View Publication.
    13. Radiosynthesis and characterization of [18F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism. Eur J Nucl Med Mol Imaging. 2021 12; 49(1):110-124. Lee SH, Denora N, Laquintana V, Mangiatordi GF, Lopedota A, Lopalco A, Cutrignelli A, Franco M, Delre P, Song IH, Kim HW, Kim SB, Park HS, Kim K, Lee SY, Youn H, Lee BC, Kim SE. PMID: 34783879; PMCID: PMC8712300.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    14. Effect of Peptide Receptor Radionuclide Therapy in Combination with Temozolomide against Tumor Angiogenesis in a Glioblastoma Model. Cancers (Basel). 2021 Oct 08; 13(19). Lee SH, Choi JY, Jung JH, Song IH, Park HS, Denora N, Leonetti F, Kim SE, Lee BC. PMID: 34638512; PMCID: PMC8507696.
      View in: PubMed   Mentions: 2  
    15. TSPO Expression Modulatory Effect of Acetylcholinesterase Inhibitor in the Ischemic Stroke Rat Model. Cells. 2021 05 29; 10(6). Song YS, Lee SH, Jung JH, Song IH, Park HS, Moon BS, Kim SE, Lee BC. PMID: 34072449; PMCID: PMC8227181.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    16. [18F]CB251 PET/MR imaging probe targeting translocator protein (TSPO) independent of its Polymorphism in a Neuroinflammation Model. Theranostics. 2020; 10(20):9315-9331. Kim K, Kim H, Bae SH, Lee SY, Kim YH, Na J, Lee CH, Lee MS, Ko GB, Kim KY, Lee SH, Song IH, Cheon GJ, Kang KW, Kim SE, Chung JK, Kim EE, Paek SH, Lee JS, Lee BC, Youn H. PMID: 32802194; PMCID: PMC7415805.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    17. A Novel TSPO-binding Radioligand, [18F]BS224, for PET Imaging of Neuroinflammation including Less Sensitivity to TSPO Human Gene Polymorphism rs6971. Journal of Nuclear Medicine. 2020; 61(1):201. Sanghee Lee, In Ho Song, Seok Yong Lee, Young Hwa Kim, Hye Won Youn, Byung Chul Lee and Sang Eun Kim. View Publication.
    18. Multimodal Imaging Probe Development for Pancreatic β Cells: From Fluorescence to PET. J Am Chem Soc. 2020 02 19; 142(7):3430-3439. Kang NY, Lee JY, Lee SH, Song IH, Hwang YH, Kim MJ, Phue WH, Agrawalla BK, Wan SYD, Lalic J, Park SJ, Kim JJ, Kwon HY, Im SH, Bae MA, Ahn JH, Lim CS, Teo AKK, Park S, Kim SE, Lee BC, Lee DY, Chang YT. PMID: 32040300.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    19. Effect of PEG chain additive on 6,8-dichloro-2-phenylimidazo[1,2-a] pyridineacetamide (CB185) as a TSPO-binding ligand. Journal of Radiopharmaceuticals and Molecular Probes. 2019; 5(2):89-100. Won Chang Lee, Sanghee Lee, Nunzio Denora, Valentino Laquintana, Byung Chul Lee, Sang Eun Kim. View Publication.
    20. Control of reactivity and selectivity of guanidinyliodonium salts toward 18F-Labeling by monitoring of protecting groups: Experiment and theory. Journal of Fluorine Chemistry. 2019; 227:109387. Keun Sam Jang, Sung-Sik Lee, Young-Ho Oh, Sanghee Lee, Sang Eun Kim, Dong Wook Kim, Byung Chul Lee, Sungyul Lee, David M. Raffel. View Publication.
    21. Cobalt-Catalyzed C-F Bond Borylation of Aryl Fluorides. Org Lett. 2018 11 16; 20(22):7249-7252. Lim S, Song D, Jeon S, Kim Y, Kim H, Lee S, Cho H, Lee BC, Kim SE, Kim K, Lee E. PMID: 30388011.
      View in: PubMed   Mentions: 6     Fields:    
    22. Pd nanoparticle-silica nanotubes (Pd@SNTs) as an efficient catalyst for Suzuki–Miyaura coupling and sp2 C–H arylation in water. Green Chemistry. 2013; 15:3468-3473. Ginam Park, Sanghee Lee, Sang Jun Son, Seunghoon Shin. View Publication.
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