Robert Flavell, MD, PhD

Title(s)Associate Professor, Radiology
SchoolSchool of Medicine
Address185 Berry Street Bldg B, #337
San Francisco CA 94158
Phone415-353-3638
ORCID ORCID Icon0000-0002-8694-1199 Additional info
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    Collapse Biography 
    Collapse Awards and Honors
    Society of Abdominal Radiology2017  - 2019Howard S. Stern Research Award
    University of California, San Francisco2017New Directions in Prostate Cancer Research Award
    Prostate Cancer Foundation2017  - 2020David Blitzer Young Investigator Award
    Department of Defense Prostate Cancer 2016Research Program Physician Research Training Grant
    University of California, San Francisco 2016Runner up, Surbeck Scholar Award
    Radiology Society of North America (RSNA) 2015Certificate of Merit
    Association of University Radiologists / American College of Radiology 2015Research Scholar Program
    Radiology Society of North America (RSNA) 2014Certificate of Merit
    University of California, San Francisco Catalyst Program 2014Catalyst Consultation Award
    National Institute of Biomedical Imaging and Bioengineering (NIBIB)2014T32 Training Grant
    American Roentgen Ray Society2013Introduction to Academic Radiology Program

    Collapse Overview 
    Collapse Overview
    Robert Flavell, MD, PhD, is the Chief of Molecular Imaging and Therapeutics Clinical Section in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He received his medical degree from Weill Cornell Medical College, and his PhD from the Rockefeller University as part of the Tri-Institutional MD PhD program. He completed his one-year internship at the Memorial Sloan­Kettering Cancer Center in New York. Dr. Flavell completed his radiology residency at UCSF, including an NIH T32 funded research fellowship, and subsequently completed a one-year fellowship in nuclear medicine. In June 2016. he joined the faculty as an Assistant Professor in Residence.

    Dr. Flavell’s laboratory, the Molecular Imaging Lab, focuses on the development of new molecular imaging tools for better understanding of disease progression in patients with prostate and other cancers. One area of interest is the relationship between acidic interstitial pH and disease progression. Solid tumors are poorly perfused and secrete acids into the adjacent interstitium, resulting in a pH which is mildly acidic, typically ranging from 6.5 – 7.0. This property has been associated with high-grade malignancy, local invasion, and metastasis in animal models. Therefore, it would be desirable to have a method which could be used in patients for monitoring tissue pH. Therefore, one focus of Dr. Flavell’s research is developing methods of imaging acidic interstitial pH with potential for clinical translation. Specifically, two methods are being developed, one of which permits whole body evaluation of areas of acidic pH using positron emission tomography (PET) imaging, and one method which permits quantitative, local determination of interstitial pH based on hyperpolarized 13C magnetic resonance spectroscopy (HP-MRS). The PET method is based on pro-drug glycosylamine derivatives of the commonly used oncologic tracer, [18F]FDG, termed [18F]FDG amines, which are blocked with an acid-labile protecting group. When exposed to the mildly acidic pH present in the interstitium of a solid tumor, the caging group decomposes, liberating native [18F]FDG, which is subsequently absorbed by the adjacent cancer cell (Flavell R.R. et al., Bioconjugate Chem., 2016). The HP-MRS method is based on the administration of a 13C labeled probe which has a predictable change in its chemical shift based on pH. By comparison to a standard curve, quantitative pH measurements can be obtained (Flavell R.R. et al. Chem. Comm. 2015). These techniques are being optimized and ongoing directions include application in animal models, with the long term goal of clinical translation. Other areas of developing interest in the laboratory include techniques for imaging of metals in the microenvironment, and imaging of a metabolic signature associated with immune activation.

    Expertise:
    Nuclear Medicine and Molecular Imaging and Therapeutics

    Specialty:
    Novel radiotracer development, oncologic imaging, PET imaging, hyperpolarized 13C magnetic resonance imaging

    Professional Interests:
    Radiology, molecular imaging, PET imaging, prostate cancer, nuclear medicine, radiochemistry, hyperpolarized 13C magnetic resonance imaging

    Education and Training:
    • Medical School: Weill Cornell Medical College, New York
    • PhD: The Rockefeller University, New York
    • Internship: Memorial Sloan­-Kettering Cancer Center, New York
    • Residency: University of California, San Francisco
    • Fellowship: University of California, San Francisco – Nuclear Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    ACE2-targeted PET radiotracers for investigating spatiotemporal distribution of SARS-CoV-2 organ injury and therapy response.
    NIH R01AI161829Sep 17, 2021 - Aug 31, 2024
    Role: Co-Principal Investigator
    A novel immunoPET imaging agent to guide treatment planning in lethal prostate cancer
    NIH R37CA251980Dec 9, 2020 - Nov 30, 2025
    Role: Principal Investigator
    Application of hyperpolarized 13C interstitial pH imaging to risk stratification in prostate cancer
    NIH R21EB026012May 1, 2018 - Jan 31, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Pathologic outcome of incidentally detected tracer-avid lesions in 68Ga-PSMA-11 PET/CT for prostate cancer. . 2024 Apr 30; umae008. Mar MD, Diwanji DD, Lowery LB, Zhang ZL, Hope HT, Behr BS, Flavell FR. .
      View in: Publisher Site   Mentions:
    2. A technique to quantify very low activities in regions of interest with a collimatorless detector. IEEE Trans Med Imaging. 2024 Mar 18; PP. Caravaca J, Bobba KN, Du S, Peter R, Gullberg GT, Bidkar AP, Flavell RR, Seo Y. PMID: 38478457.
      View in: PubMed   Mentions:    Fields:    
    3. Bioorthogonal Radiolabeling of Azide-Modified Bacteria Using [18F]FB-sulfo-DBCO. Bioconjug Chem. 2024 Mar 14. Alanizi AA, Sorlin AM, Parker MFL, López-Álvarez M, Qin H, Lee SH, Blecha J, Rosenberg OS, Engel J, Ohliger MA, Flavell RR, Wilson DM. PMID: 38482815.
      View in: PubMed   Mentions:    Fields:    
    4. 18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy. Radiol Imaging Cancer. 2024 Mar; 6(2):e230082. Diwanji D, Onishi N, Hathi DK, Lawhn-Heath C, Kornak J, Li W, Guo R, Molina-Vega J, Seo Y, Flavell RR, Heditsian D, Brain S, Esserman LJ, Joe BN, Hylton NM, Jones EF, Ray KM. PMID: 38551406.
      View in: PubMed   Mentions:    Fields:    
    5. CD46-Targeted Theranostics for PET and 225Ac-Radiopharmaceutical Therapy of Multiple Myeloma. Clin Cancer Res. 2024 03 01; 30(5):1009-1021. Wadhwa A, Wang S, Patiño-Escobar B, Bidkar AP, Bobba KN, Chan E, Meher N, Bidlingmaier S, Su Y, Dhrona S, Geng H, Sarin V, VanBrocklin HF, Wilson DM, He J, Zhang L, Steri V, Wong SW, Martin TG, Seo Y, Liu B, Wiita AP, Flavell RR. PMID: 38109209; PMCID: PMC10905524.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Peptidoglycan-Targeted [18F]3,3,3-Trifluoro-d-alanine Tracer for Imaging Bacterial Infection. JACS Au. 2024 Mar 25; 4(3):1039-1047. Sorlin AM, López-Álvarez M, Biboy J, Gray J, Rabbitt SJ, Rahim JU, Lee SH, Bobba KN, Blecha J, Parker MFL, Flavell RR, Engel J, Ohliger M, Vollmer W, Wilson DM. PMID: 38559735; PMCID: PMC10976610.
      View in: PubMed   Mentions:
    7. Development of CD46 targeted alpha theranostics in prostate cancer using 134Ce/225Ac-Macropa-PEG4-YS5. Theranostics. 2024; 14(4):1344-1360. Bobba KN, Bidkar AP, Wadhwa A, Meher N, Drona S, Sorlin AM, Bidlingmaier S, Zhang L, Wilson DM, Chan E, Greenland NY, Aggarwal R, VanBrocklin HF, He J, Chou J, Seo Y, Liu B, Flavell RR. PMID: 38389832; PMCID: PMC10879874.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    8. Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography Radiotracers. ACS Sens. 2023 Dec 22; 8(12):4554-4565. Lee SH, Kim JM, López-Álvarez M, Wang C, Sorlin AM, Bobba KN, Pichardo-González PA, Blecha J, Seo Y, Flavell RR, Engel J, Ohliger MA, Wilson DM. PMID: 37992233; PMCID: PMC10749472.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. O-04 StarPEG Nanocarriers for PSMA Targeted Radioligand Imaging and Therapy. Nuclear Medicine and Biology. 2023 Nov 1; 126:108400. Bidkar BA, Meher MN, Ashley AG, Wadhwa WA, Bobba BK, Shuere SB, Wilson WD, Seo SY, Santi SD, VanBrocklin VH, Flavell FR. .
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    10. O-14 Evaluation of 134Ce/La pair as a PET imaging surrogate for 225Ac radiotherapeutics. Nuclear Medicine and Biology. 2023 Nov 1; 126:108410. Bobba BK, Bidkar BA, Meher MN, Fong FC, Wadhwa WA, Dhrona DS, Sorlin SA, Bidlingmaier BS, Shuere SB, He HJ, Wilson WD, Liu LB, Seo SY, VanBrocklin VH, Flavell FR. .
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    11. O-77 Molecular imaging and radiopharmaceutical therapy of Multiple Myeloma targeting CD46 using 89Zr and 225Ac-YS5. Nuclear Medicine and Biology. 2023 Nov 1; 126:108473. Wadhwa WA, Wang WS, Escobar EB, Bidkar BA, Bobba BK, Meher MN, Dhrona DS, Wong WS, Wilson WD, VanBrocklin VH, Seo SY, Liu LB, Wiita WA, Flavell FR. .
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    12. P-288 Alpha particle therapy for the treatment of metastatic tumors of prostate cancer. Nuclear Medicine and Biology. 2023 Nov 1; 126:108749. Bidkar BA, Wadhwa WA, Bobba BK, Meher MN, Bidlingmaier BS, Egusa EE, Ali AU, Dhrona DS, Su SY, He HJ, Wilson WD, Aggarwal AR, VanBrocklin VH, Seo SY, Chou CJ, Flavell FR. .
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    13. P-171 StarPEG Nanocarriers for Prostate Cancer Imaging and Drug Delivery. Nuclear Medicine and Biology. 2023 Nov 1; 126:108640. Meher MN, Ashley AG, Bidkar BA, Wadhwa WA, Bobba BK, Dhrona DS, Fontaine FS, Beckford-Vera BD, Fong FC, Wilson WD, Seo SY, Santi SD, VanBrocklin VH, Flavell FR. .
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    14. Clinically Translatable Hyperpolarized 13C Bicarbonate pH Imaging Method for Use in Prostate Cancer. ACS Sens. 2023 11 24; 8(11):4042-4054. Mu C, Liu X, Kim Y, Riselli A, Korenchan DE, Bok RA, Delos Santos R, Sriram R, Qin H, Nguyen H, Gordon JW, Slater J, Larson PEZ, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 37878761; PMCID: PMC10683509.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    15. Evaluating the Performance of Pathogen-Targeted Positron Emission Tomography Radiotracers in a Rat Model of Vertebral Discitis-Osteomyelitis. J Infect Dis. 2023 10 03; 228(Suppl 4):S281-S290. Parker MFL, López-Álvarez M, Alanizi AA, Luu JM, Polvoy I, Sorlin AM, Qin H, Lee S, Rabbitt SJ, Pichardo-González PA, Ordonez AA, Blecha J, Rosenberg OS, Flavell RR, Engel J, Jain SK, Ohliger MA, Wilson DM. PMID: 37788505.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    16. Coded aperture and Compton imaging for the development of 225 Ac-based radiopharmaceuticals. Med Phys. 2023 Oct; 50(10):6454-6468. Frame E, Bobba K, Gunter D, Mihailescu L, Bidkar A, Flavell R, Vetter K. PMID: 37672346.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    17. Chemoenzymatic Syntheses of Fluorine-18-Labeled Disaccharides from [18F] FDG Yield Potent Sensors of Living Bacteria In Vivo. J Am Chem Soc. 2023 08 16; 145(32):17632-17642. Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, Fraser JS, Wilson DM. PMID: 37535945; PMCID: PMC10436271.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19. medRxiv. 2023 Jul 31. Peluso MJ, Ryder D, Flavell R, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez A, Buitrago M, Tai V, Shrestha U, Lu S, Goldberg SA, Dalhuisen T, Durstenfeld MS, Hsue PY, Kelly JD, Kumar N, Martin JN, Gambir A, Somsouk M, Seo Y, Deeks SG, Laszik ZG, VanBrocklin HF, Henrich TJ. PMID: 37577714; PMCID: PMC10418298.
      View in: PubMed   Mentions:
    19. Beyond Anatomy: The Role of Molecular Imaging in the Evaluation of Low Back Pain. Current Radiology Reports. 2023 Jul 19; 1-11. Sweetwood SK, Junn JJ, Qiao QY, Berven BS, Shah SV, Pampaloni PM, Flavell FR, Dillon DW, Talbott TJ, Lawhn-Heath LC. .
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    20. Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects. ACS Cent Sci. 2023 Jun 28; 9(6):1241-1251. Klauser PC, Chopra S, Cao L, Bobba KN, Yu B, Seo Y, Chan E, Flavell RR, Evans MJ, Wang L. PMID: 37396859; PMCID: PMC10311652.
      View in: PubMed   Mentions: 3  
    21. Chemoenzymatic syntheses of fluorine-18-labeled disaccharides from [ 18 F]FDG yield potent sensors of living bacteria in vivo. bioRxiv. 2023 May 20. Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, Fraser JS, Wilson DM. PMID: 37293043; PMCID: PMC10245702.
      View in: PubMed   Mentions:
    22. Evaluation of 134Ce/134La as a PET Imaging Theranostic Pair for 225Ac α-Radiotherapeutics. J Nucl Med. 2023 07; 64(7):1076-1082. Bobba KN, Bidkar AP, Meher N, Fong C, Wadhwa A, Dhrona S, Sorlin A, Bidlingmaier S, Shuere B, He J, Wilson DM, Liu B, Seo Y, VanBrocklin HF, Flavell RR. PMID: 37201957; PMCID: PMC10315697.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    23. Treatment of Prostate Cancer with CD46-targeted 225Ac Alpha Particle Radioimmunotherapy. Clin Cancer Res. 2023 05 15; 29(10):1916-1928. Bidkar AP, Wang S, Bobba KN, Chan E, Bidlingmaier S, Egusa EA, Peter R, Ali U, Meher N, Wadhwa A, Dhrona S, Dasari C, Beckford-Vera D, Su Y, Tang R, Zhang L, He J, Wilson DM, Aggarwal R, VanBrocklin HF, Seo Y, Chou J, Liu B, Flavell RR. PMID: 36917693; PMCID: PMC10183825.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    24. CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment. J Exp Clin Cancer Res. 2023 Mar 11; 42(1):61. Li J, Huang T, Hua J, Wang Q, Su Y, Chen P, Bidlingmaier S, Li A, Xie Z, Bidkar AP, Shen S, Shi W, Seo Y, Flavell RR, Gioeli D, Dreicer R, Li H, Liu B, He J. PMID: 36906664; PMCID: PMC10007843.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    25. PSMA-Targeted Nanotheranostics for Imaging and Radiotherapy of Prostate Cancer. Pharmaceuticals (Basel). 2023 Feb 17; 16(2). Meher N, VanBrocklin HF, Wilson DM, Flavell RR. PMID: 37259457; PMCID: PMC9964110.
      View in: PubMed   Mentions: 3  
    26. Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer. Cancer Res. 2023 01 18; 83(2):301-315. Chou J, Egusa EA, Wang S, Badura ML, Lee F, Bidkar AP, Zhu J, Shenoy T, Trepka K, Robinson TM, Steri V, Huang J, Wang Y, Small EJ, Chan E, Stohr BA, Ashworth A, Delafontaine B, Rottey S, Cooke KS, Hashemi Sadraei N, Yu B, Salvati M, Bailis JM, Feng FY, Flavell RR, Aggarwal R. PMID: 36351060; PMCID: PMC10263373.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    27. Retrospective study of the incidence of sarcoidosis-like reaction in patients treated with immunotherapy. Clin Radiol. 2023 02; 78(2):e131-e136. Li Y, Flavell RR, Juarez R, Chow M, Wu C, Tsai K, Daud A, Behr SC. PMID: 36344282.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Prostate-Specific Membrane Antigen Targeted Deep Tumor Penetration of Polymer Nanocarriers. ACS Appl Mater Interfaces. 2022 Nov 16; 14(45):50569-50582. Meher N, Ashley GW, Bidkar AP, Dhrona S, Fong C, Fontaine SD, Beckford Vera DR, Wilson DM, Seo Y, Santi DV, VanBrocklin HF, Flavell RR. PMID: 36318757; PMCID: PMC9673064.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    29. P-65 Cyclic [68Ga] and [18F]AlF-labeled peptides for specific detection of human angiotensin-converting enzyme 2. Nuclear Medicine and Biology. 2022 Nov 1; 114:s64-s65. Wilson WD, Anju AA, Parker PM, Meher MN, Blecha BJ, Rosenberg RO, Ohliger OM, Flavell FR. .
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    30. O-46 Treatment of prostate cancer xenografts with the targeted alpha-particle nanogenerator [225Ac]Ac-DOTA-YS5. Nuclear Medicine and Biology. 2022 Nov 1; 114:s31. Bidkar BA, Wang WS, Bobba BK, Bidlingmaier BS, Su SY, Egusa EE, Tang TR, Chou CJ, Aggarwal AR, He HJ, Seo SY, Liu LB, Flavell FR. .
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    31. Antigen-Dependent Inducible T-Cell Reporter System for PET Imaging of Breast Cancer and Glioblastoma. J Nucl Med. 2023 01; 64(1):137-144. Shin J, Parker MFL, Zhu I, Alanizi A, Rodriguez CI, Liu R, Watchmaker PB, Kalita M, Blecha J, Luu J, Wright B, Lapi SE, Flavell RR, Okada H, Tlsty TD, Roybal KT, Wilson DM. PMID: 35981900; PMCID: PMC9841254.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    32. 177Lu-PSMA Therapy. J Nucl Med Technol. 2022 Sep; 50(3):205-212. Parent EE, Savir-Baruch B, Gayed IW, Almaguel F, Chin BB, Pantel AR, Armstrong E, Morley A, Ippisch RC, Flavell RR. PMID: 36215646.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Nuclear imaging of bacterial infection: the state of the art and future directions. Chinese Journal of Nuclear Medicine and Molecular Imaging. 2022 Jul 25; 42(07):436-444. Polvoy PI, Flavell FR, Rosenberg RO, Ohliger OM, Wilson WD. .
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    34. Non-Iodine-Avid Disease Is Highly Prevalent in Distant Metastatic Differentiated Thyroid Cancer With Papillary Histology. J Clin Endocrinol Metab. 2022 07 14; 107(8):e3206-e3216. Soe MH, Chiang JM, Flavell RR, Khanafshar E, Mendoza L, Kang H, Liu C. PMID: 35556126; PMCID: PMC9282362.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    35. Imaging joint infections using D-methyl-11C-methionine PET/MRI: initial experience in humans. Eur J Nucl Med Mol Imaging. 2022 09; 49(11):3761-3771. Polvoy I, Seo Y, Parker M, Stewart M, Siddiqua K, Manacsa HS, Ravanfar V, Blecha J, Hope TA, Vanbrocklin H, Flavell RR, Barry J, Hansen E, Villanueva-Meyer JE, Engel J, Rosenberg OS, Wilson DM, Ohliger MA. PMID: 35732972; PMCID: PMC9399217.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    36. Imaging of solid tumors using 68Ga-FAP-2286. Journal of Clinical Oncology. 2022 Jun 1; 40(16_suppl):3059-3059. Hope HT, Aggarwal AR, Dhawan DM, Kelley KR, Flavell FR, Lawhn Heath LC, Li LY, Porten PS, Rugo RH, Yom YS, Ippisch IR, Koshkin KV. .
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    37. Development of specialized magnetic resonance acquisition techniques for human hyperpolarized [13 C,15 N2 ]urea + [1-13 C]pyruvate simultaneous perfusion and metabolic imaging. Magn Reson Med. 2022 09; 88(3):1039-1054. Liu X, Tang S, Mu C, Qin H, Cui D, Lai YC, Riselli AM, Delos Santos R, Carvajal L, Gebrezgiabhier D, Bok RA, Chen HY, Flavell RR, Gordon JW, Vigneron DB, Kurhanewicz J, Larson PEZ. PMID: 35526263; PMCID: PMC9810116.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    38. P-003 Influence of short PEG linkers on biodistribution of 225Ac-Macropa-YS5, an immunoconjugate for treating CD46 expressing cancer. Nuclear Medicine and Biology. 2022 May 1; 108:s53. Bobba BK, Bidkar BA, Wang WS, Bidlingmaier BS, Tang TR, Su SY, VanBrocklin VH, Liu LB, Seo SY, Flavell FR. .
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    39. O-08 Efficient chelation of 134Ce/La using the macrocyclic chelators DOTA and Macropa as potential PET imaging agents. Nuclear Medicine and Biology. 2022 May 1; 108:s8-s9. Bobba BK, Fong FC, Bidkar BA, Tang TR, Bidlingmaier BS, Liu LB, Seo SY, VanBrocklin VH, Flavell FR. .
      View in: Publisher Site   Mentions:
    40. O-46 CD46 targeted, Actinium-225 labelled antibody for treatment of prostate cancer xenografts. Nuclear Medicine and Biology. 2022 May 1; 108:s31. Bidkar BA, Wang WS, Bobba BK, Bidlingmaier BS, Su SY, Egusa EE, Tang TR, Chou CJ, Aggarwal AR, He HJ, Seo SY, Liu LB, Flavell FR. .
      View in: Publisher Site   Mentions:
    41. First-in-human immunoPET imaging of HIV-1 infection using 89Zr-labeled VRC01 broadly neutralizing antibody. Nat Commun. 2022 03 09; 13(1):1219. Beckford-Vera DR, Flavell RR, Seo Y, Martinez-Ortiz E, Aslam M, Thanh C, Fehrman E, Pardons M, Kumar S, Deitchman AN, Ravanfar V, Schulte B, Wu IK, Pan T, Reeves JD, Nixon CC, Iyer NS, Torres L, Munter SE, Hyunh T, Petropoulos CJ, Hoh R, Franc BL, Gama L, Koup RA, Mascola JR, Chomont N, Deeks SG, VanBrocklin HF, Henrich TJ. PMID: 35264559; PMCID: PMC8907355.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    42. Dosimetry in radionuclide therapy: the clinical role of measuring radiation dose. Lancet Oncol. 2022 02; 23(2):e75-e87. Lawhn-Heath C, Hope TA, Martinez J, Fung EK, Shin J, Seo Y, Flavell RR. PMID: 35114134.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    43. Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen. ACS Appl Mater Interfaces. 2021 Nov 24; 13(46):54739-54752. Meher N, Seo K, Wang S, Bidkar AP, Fogarty M, Dhrona S, Huang X, Tang R, Blaha C, Evans MJ, Raleigh DR, Jun YW, VanBrocklin HF, Desai TA, Wilson DM, Ozawa T, Flavell RR. PMID: 34752058.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    44. Prostate cancer research in the 21st century; report from the 2021 Coffey-Holden prostate cancer academy meeting. Prostate. 2022 02; 82(2):169-181. Miyahira AK, Zarif JC, Coombs CC, Flavell RR, Russo JW, Zaidi S, Zhao D, Zhao SG, Pienta KJ, Soule HR. PMID: 34734426; PMCID: PMC8688282.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Deuterium Metabolic Imaging-Rediscovery of a Spectroscopic Tool. Metabolites. 2021 Aug 25; 11(9). Polvoy I, Qin H, Flavell RR, Gordon J, Viswanath P, Sriram R, Ohliger MA, Wilson DM. PMID: 34564385; PMCID: PMC8470013.
      View in: PubMed   Mentions: 8  
    46. Synthesis of N-trifluoromethyl amides from carboxylic acids. Chem. 2021 Aug 12; 7(8):2245-2255. Liu J, Parker MFL, Wang S, Flavell RR, Toste FD, Wilson DM. PMID: 35509497; PMCID: PMC9060565.
      View in: PubMed   Mentions: 3  
    47. Authors' Reply: To the Letter to the Editor by Groheux et al. J Natl Compr Canc Netw. 2021 08 01; 19(8):xxx-xxxii. Heath CL, Esserman LJ, Flavell RR, Melisko ME. PMID: 34416710.
      View in: PubMed   Mentions:    Fields:    
    48. Causes of False-Positive Radioactive Iodine Uptake in Patients with Differentiated Thyroid Cancer. Current Radiology Reports. 2021 May 19; 9(6):6. Wu WK, Ozomaro OU, Flavell FR, Pampaloni PM, Liu LC. .
      View in: Publisher Site   Mentions:
    49. Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone. Front Oncol. 2021; 11:589570. Batsios G, Taglang C, Cao P, Gillespie AM, Najac C, Subramani E, Wilson DM, Flavell RR, Larson PEZ, Ronen SM, Viswanath P. PMID: 33937017; PMCID: PMC8082394.
      View in: PubMed   Mentions: 5  
    50. Gastrointestinal Stromal Tumor Incidentally Detected on 18F-Fluciclovine PET/CT. Clin Nucl Med. 2021 Apr 01; 46(4):345-347. Raghavan K, Flavell RR, Westphalen AC, Behr SC. PMID: 33234933.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. TBMT-01. HYPERPOLARIZED d-[1-13C]GLUCONOLACTONE MONITORS TERT-INDUCED ELEVATION IN PENTOSE PHOSPHATE PATHWAY FLUX IN BRAIN TUMORS IN VIVO. Neuro-Oncology Advances. 2021 Mar 25; 3(Supplement_1):i20-i20. Batsios BG, Viswanath VP, Taglang TC, Flavell FR, Costello CJ, Pieper PR, Larson LP, Ronen RS. .
      View in: Publisher Site   Mentions:
    52. Cyclic 68Ga-Labeled Peptides for Specific Detection of Human Angiotensin-Converting Enzyme 2. J Nucl Med. 2021 11; 62(11):1631-1637. Parker MFL, Blecha J, Rosenberg O, Ohliger M, Flavell RR, Wilson DM. PMID: 33637588; PMCID: PMC8612341.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    53. Abstract PS13-50: Relationship of dedicated breast PET and MRI features in breast cancer patients receiving neoadjuvant chemotherapy. Cancer Research. 2021 Feb 15; 81(4_Supplement):ps13-50-ps13-50. Hathi HD, Jones JE, Li LW, Newitt ND, Guo GR, Seo SY, Flavell FR, Joe JB, Heditsian HD, Brain BS, Esserman EL, Hylton HN. .
      View in: Publisher Site   Mentions:
    54. Tumor Microenvironment Biosensors for Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopy. Mol Imaging Biol. 2021 06; 23(3):323-334. Mu C, Korenchan DE, Wang S, Wilson DM, Flavell RR. PMID: 33415679; PMCID: PMC8105261.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    55. Evaluation of primary breast cancers using dedicated breast PET and whole-body PET. Sci Rep. 2020 12 14; 10(1):21930. Hathi DK, Li W, Seo Y, Flavell RR, Kornak J, Franc BL, Joe BN, Esserman LJ, Hylton NM, Jones EF. PMID: 33318514; PMCID: PMC7736887.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    56. Molecular Imaging of Prostate Cancer Targeting CD46 Using ImmunoPET. Clin Cancer Res. 2021 03 01; 27(5):1305-1315. Wang S, Li J, Hua J, Su Y, Beckford-Vera DR, Zhao W, Jayaraman M, Huynh TL, Zhao N, Wang YH, Huang Y, Qin F, Shen S, Gioeli D, Dreicer R, Sriram R, Egusa EA, Chou J, Feng FY, Aggarwal R, Evans MJ, Seo Y, Liu B, Flavell RR, He J. PMID: 33293372; PMCID: PMC7925362.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    57. Management of Challenging Radioiodine Treatment Protocols: A Case Series and Review of the Literature. J Nucl Med Technol. 2021 Jun; 49(2):180-185. Waller J, Lawhn-Heath CA, Edmonds C, Wendorf C, Holmes B, White M, Pampaloni MH, Liu C, Flavell RR. PMID: 33219159.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    58. Use of 18F-FDG PET/CT as an Initial Staging Procedure for Stage II-III Breast Cancer: A Multicenter Value Analysis. J Natl Compr Canc Netw. 2020 11; 18(11):1510-1517. Hyland CJ, Varghese F, Yau C, Beckwith H, Khoury K, Varnado W, Hirst GL, Flavell RR, Chien AJ, Yee D, Isaacs CJ, Forero-Torres A, Esserman LJ, Melisko ME. PMID: 33152704.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    59. Gallium-68 prostate-specific membrane antigen ([68Ga]Ga-PSMA-11) PET for imaging of thyroid cancer: a feasibility study. EJNMMI Res. 2020 Oct 22; 10(1):128. Lawhn-Heath C, Yom SS, Liu C, Villanueva-Meyer JE, Aslam M, Smith R, Narwal M, Juarez R, Behr SC, Pampaloni MH, Chan JW, Glastonbury CM, Hope TA, Flavell RR. PMID: 33090273; PMCID: PMC7581659.
      View in: PubMed   Mentions: 12  
    60. The Synthesis and Structural Requirements for Measuring Glucocorticoid Receptor Expression In Vivo with (±)-11C-YJH08 PET. J Nucl Med. 2021 05 10; 62(5):723-731. Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Parker MFL, Blecha JE, Drake CR, VanBrocklin HF, Garrido-Ruiz D, Jacobson MP, Aggarwal R, Behr SC, Flavell RR, Wilson DM, Seo Y, Evans MJ. PMID: 32887758; PMCID: PMC8844266.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    61. 68Ga-PSMA-11 PET/MRI: determining ideal acquisition times to reduce noise and increase image quality. EJNMMI Phys. 2020 Aug 26; 7(1):54. Murthy V, Smith RL, Tao DH, Lawhn-Heath CA, Korenchan DE, Larson PEZ, Flavell RR, Hope TA. PMID: 32844310; PMCID: PMC7447708.
      View in: PubMed   Mentions: 3  
    62. An Analysis of Isoclonal Antibody Formats Suggests a Role for Measuring PD-L1 with Low Molecular Weight PET Radiotracers. Mol Imaging Biol. 2020 12; 22(6):1553-1561. Wei J, Wang YH, Lee CY, Truillet C, Oh DY, Xu Y, Ruggero D, Flavell RR, VanBrocklin HF, Seo Y, Craik CS, Fong L, Wang CI, Evans MJ. PMID: 32813112; PMCID: PMC7669684.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    63. PET/CT in Surgical Planning for Head and Neck Cancer. Semin Nucl Med. 2021 01; 51(1):50-58. Strohl MP, Ha PK, Flavell RR, Yom SS. PMID: 33246539.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    64. Nuclear Imaging of Bacterial Infection: The State of the Art and Future Directions. J Nucl Med. 2020 12; 61(12):1708-1716. Polvoy I, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 32764120; PMCID: PMC9364899.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    65. High Accuracy of PSMA PET in Initial Staging of High-Risk Prostate Cancer. Radiol Imaging Cancer. 2020 07; 2(4):e204025. Waller J, Flavell R, Heath CL. PMID: 33778731; PMCID: PMC7983724.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    66. 800 Impact of 68Ga-PSMA-11 PET on the management of biochemically recurrent prostate cancer in a prospective single-arm clinical trial. . 2020 Jul 1; 19:e1215-e1216. Ferdinandus FJ, Fendler FW, Calais CJ, Eiber EM, Flavell FR, Mishoe MA, Feng FF, Nguyen NH, Reiter RR, Rettig RM, Gartmann GJ, Smith SR, Small SE, Slavik SR, Carroll CP, Herrmann HK, Czernin CJ, Hope HT. .
      View in: Publisher Site   Mentions:
    67. Understanding Response to Immunotherapy Using Standard of Care and Experimental Imaging Approaches. Int J Radiat Oncol Biol Phys. 2020 09 01; 108(1):242-257. Flavell RR, Evans MJ, Villanueva-Meyer JE, Yom SS. PMID: 32585333.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    68. Small Molecule Sensors Targeting the Bacterial Cell Wall. ACS Infect Dis. 2020 07 10; 6(7):1587-1598. Parker MFL, Flavell RR, Luu JM, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 32433879; PMCID: PMC7808209.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    69. Impact of 68Ga-PSMA-11 PET on the Management of Recurrent Prostate Cancer in a Prospective Single-Arm Clinical Trial. J Nucl Med. 2020 12; 61(12):1793-1799. Fendler WP, Ferdinandus J, Czernin J, Eiber M, Flavell RR, Behr SC, Wu IK, Lawhn-Heath C, Pampaloni MH, Reiter RE, Rettig MB, Gartmann J, Murthy V, Slavik R, Carroll PR, Herrmann K, Calais J, Hope TA. PMID: 32358094; PMCID: PMC9364898.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCTClinical Trials
    70. Factors Predicting Metastatic Disease in 68Ga-PSMA-11 PET-Positive Osseous Lesions in Prostate Cancer. J Nucl Med. 2020 12; 61(12):1779-1785. Chiu LW, Lawhn-Heath C, Behr SC, Juarez R, Perez PM, Lobach I, Bucknor MD, Hope TA, Flavell RR. PMID: 32303599.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    71. Arabinofuranose-derived positron-emission tomography radiotracers for detection of pathogenic microorganisms. J Labelled Comp Radiopharm. 2020 05 15; 63(5):231-239. Kalita M, Parker MFL, Luu JM, Stewart MN, Blecha JE, VanBrocklin HF, Evans MJ, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 32222086; PMCID: PMC7364301.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    72. Impact of 68Ga-PSMA-11 PET on the management of biochemically recurrent prostate cancer in a prospective single-arm clinical trial. Journal of Clinical Oncology. 2020 Feb 20; 38(6_suppl):292-292. Fendler FW, Ferdinandus FJ, Calais CJ, Eiber EM, Flavell FR, Mishoe MA, Feng FF, Nguyen NH, Reiter RR, Rettig RM, Gartmann GJ, Smith SR, Small SE, Slavik SR, Carroll CP, Herrmann HK, Czernin CJ, Hope HT. .
      View in: Publisher Site   Mentions:
    73. Sensing Living Bacteria in Vivo Using d-Alanine-Derived 11C Radiotracers. ACS Cent Sci. 2020 Feb 26; 6(2):155-165. Parker MFL, Luu JM, Schulte B, Huynh TL, Stewart MN, Sriram R, Yu MA, Jivan S, Turnbaugh PJ, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 32123733; PMCID: PMC7047270.
      View in: PubMed   Mentions: 23  
    74. Quantitative and Qualitative Improvement of Low-Count [68Ga]Citrate and [90Y]Microspheres PET Image Reconstructions Using Block Sequential Regularized Expectation Maximization Algorithm. Mol Imaging Biol. 2020 02; 22(1):208-216. Seo Y, Khalighi MM, Wangerin KA, Deller TW, Wang YH, Jivan S, Kohi MP, Aggarwal R, Flavell RR, Behr SC, Evans MJ. PMID: 30993558; PMCID: PMC6800603.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    75. Failure of iodine uptake in microscopic pulmonary metastases after recombinant human thyroid-stimulating hormone stimulation. World J Nucl Med. 2020 Jan-Mar; 19(1):61-64. Lawhn-Heath C, Flavell RR, Chuang EY, Liu C. PMID: 32190026; PMCID: PMC7067131.
      View in: PubMed   Mentions:
    76. Preclinical SPECT and SPECT-CT in Oncology. Recent Results Cancer Res. 2020; 216:359-404. Franc BL, Seo Y, Flavell R, Aparici CM. PMID: 32594393.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    77. High Enantiomeric Excess In-Loop Synthesis of d-[methyl-11C]Methionine for Use as a Diagnostic Positron Emission Tomography Radiotracer in Bacterial Infection. ACS Infect Dis. 2020 01 10; 6(1):43-49. Stewart MN, Parker MFL, Jivan S, Luu JM, Huynh TL, Schulte B, Seo Y, Blecha JE, Villanueva-Meyer JE, Flavell RR, VanBrocklin HF, Ohliger MA, Rosenberg O, Wilson DM. PMID: 31697062; PMCID: PMC7364312.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    78. CBMT-08. IN VIVO EVALUATION OF PENTOSE PHOSPHATE PATHWAY ACTIVITY IN ORTHOTOPIC GLIOMA USING HYPERPOLARIZED d-[1-13C]GLUCONOLACTONE. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi34-vi34. Batsios BG, Viswanath VP, Cao CP, Taglang TC, Subramani SE, Flavell FR, Larson LP, Ronen RS. .
      View in: Publisher Site   Mentions:
    79. Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer. Oncotarget. 2019 Oct 22; 10(58):6096-6110. Korenchan DE, Bok R, Sriram R, Liu K, Santos RD, Qin H, Lobach I, Korn N, Wilson DM, Kurhanewicz J, Flavell RR. PMID: 31692908; PMCID: PMC6817439.
      View in: PubMed   Mentions: 6     Fields:    
    80. Amino Acid-Derived Sensors for Specific Zn2+ Detection Using Hyperpolarized 13 C Magnetic Resonance Spectroscopy. Chemistry. 2019 Sep 12; 25(51):11842-11846. Wang S, Korenchan DE, Perez PM, Taglang C, Hayes TR, Sriram R, Bok R, Hong AS, Wu Y, Li H, Wang Z, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 31338914; PMCID: PMC6742520.
      View in: PubMed   Mentions: 4     Fields:    
    81. Synthesis and Initial Biological Evaluation of Boron-Containing Prostate-Specific Membrane Antigen Ligands for Treatment of Prostate Cancer Using Boron Neutron Capture Therapy. Mol Pharm. 2019 09 03; 16(9):3831-3841. Wang S, Blaha C, Santos R, Huynh T, Hayes TR, Beckford-Vera DR, Blecha JE, Hong AS, Fogarty M, Hope TA, Raleigh DR, Wilson DM, Evans MJ, VanBrocklin HF, Ozawa T, Flavell RR. PMID: 31381351; PMCID: PMC6722010.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    82. Spatiotemporal pH Heterogeneity as a Promoter of Cancer Progression and Therapeutic Resistance. Cancers (Basel). 2019 Jul 20; 11(7). Korenchan DE, Flavell RR. PMID: 31330859; PMCID: PMC6678451.
      View in: PubMed   Mentions: 23  
    83. Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial. JAMA Oncol. 2019 Jun 01; 5(6):856-863. Fendler WP, Calais J, Eiber M, Flavell RR, Mishoe A, Feng FY, Nguyen HG, Reiter RE, Rettig MB, Okamoto S, Emmett L, Zacho HD, Ilhan H, Wetter A, Rischpler C, Schoder H, Burger IA, Gartmann J, Smith R, Small EJ, Slavik R, Carroll PR, Herrmann K, Czernin J, Hope TA. PMID: 30920593; PMCID: PMC6567829.
      View in: PubMed   Mentions: 231     Fields:    Translation:HumansCTClinical Trials
    84. Using bidirectional chemical exchange for improved hyperpolarized [13 C]bicarbonate pH imaging. Magn Reson Med. 2019 09; 82(3):959-972. Korenchan DE, Gordon JW, Subramaniam S, Sriram R, Baligand C, VanCriekinge M, Bok R, Vigneron DB, Wilson DM, Larson PEZ, Kurhanewicz J, Flavell RR. PMID: 31050049; PMCID: PMC6559833.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    85. Incidentally Detected Oropharyngeal Squamous Cell Carcinoma on 18F-Fluciclovine PET/CT. Clin Nucl Med. 2019 May; 44(5):e367-e369. Raghavan K, Wen KW, Small EJ, Ha P, Flavell RR. PMID: 30829856.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    86. Single-Center Prospective Evaluation of 68Ga-PSMA-11 PET in Biochemical Recurrence of Prostate Cancer. AJR Am J Roentgenol. 2019 08; 213(2):266-274. Lawhn-Heath C, Flavell RR, Behr SC, Yohannan T, Greene KL, Feng F, Carroll PR, Hope TA. PMID: 31039025.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    87. Molecular Imaging of Renal Malignancy: A Review. Current Radiology Reports. 2019 Apr 1; 7(4):12. Graybiel GC, Flavell FR, Wang WZ, Behr BS. .
      View in: Publisher Site   Mentions:
    88. Heterogeneous Uptake of 18F-FDG and 68Ga-PSMA-11 in Hepatocellular Carcinoma. Clin Nucl Med. 2019 Mar; 44(3):e133-e135. Perez PM, Flavell RR, Kelley RK, Umetsu S, Behr SC. PMID: 30624275.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    89. The Role of Lactate Metabolism in Prostate Cancer Progression and Metastases Revealed by Dual-Agent Hyperpolarized 13C MRSI. Cancers (Basel). 2019 Feb 22; 11(2). Bok R, Lee J, Sriram R, Keshari K, Sukumar S, Daneshmandi S, Korenchan DE, Flavell RR, Vigneron DB, Kurhanewicz J, Seth P. PMID: 30813322; PMCID: PMC6406929.
      View in: PubMed   Mentions: 24  
    90. Intertumoral Heterogeneity of 18F-FDG and 68Ga-PSMA Uptake in Prostate Cancer Pulmonary Metastases. Clin Nucl Med. 2019 Jan; 44(1):e28-e32. Perez PM, Hope TA, Behr SC, van Zante A, Small EJ, Flavell RR. PMID: 30394930.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    91. Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer. J Nucl Med. 2019 07; 60(7):910-916. Behr SC, Aggarwal R, VanBrocklin HF, Flavell RR, Gao K, Small EJ, Blecha J, Jivan S, Hope TA, Simko JP, Kurhanewicz J, Noworolski SM, Korn NJ, De Los Santos R, Cooperberg MR, Carroll PR, Nguyen HG, Greene KL, Langton-Webster B, Berkman CE, Seo Y. PMID: 30464040; PMCID: PMC6604687.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    92. A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain. Radiology. 2019 02; 290(2):456-464. Ding Y, Sohn JH, Kawczynski MG, Trivedi H, Harnish R, Jenkins NW, Lituiev D, Copeland TP, Aboian MS, Mari Aparici C, Behr SC, Flavell RR, Huang SY, Zalocusky KA, Nardo L, Seo Y, Hawkins RA, Hernandez Pampaloni M, Hadley D, Franc BL. PMID: 30398430; PMCID: PMC6358051.
      View in: PubMed   Mentions: 137     Fields:    Translation:Humans
    93. Detection of Metastatic Meningioma to the Liver Using 68Ga-DOTA-Octreotate PET/CT. Clin Nucl Med. 2018 Sep; 43(9):e338-e340. Villanueva-Meyer JE, Magill ST, Lee JC, Umetsu SE, Flavell RR. PMID: 29939957.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    94. Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes. Sci Rep. 2018 05 21; 8(1):7928. Qin H, Carroll VN, Sriram R, Villanueva-Meyer JE, von Morze C, Wang ZJ, Mutch CA, Keshari KR, Flavell RR, Kurhanewicz J, Wilson DM. PMID: 29786697; PMCID: PMC5962598.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    95. Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI. Chem Commun (Camb). 2018 May 17; 54(41):5233-5236. Taglang C, Korenchan DE, von Morze C, Yu J, Najac C, Wang S, Blecha JE, Subramaniam S, Bok R, VanBrocklin HF, Vigneron DB, Ronen SM, Sriram R, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 29726563; PMCID: PMC6054790.
      View in: PubMed   Mentions: 16     Fields:    
    96. [11C]Para-Aminobenzoic Acid: A Positron Emission Tomography Tracer Targeting Bacteria-Specific Metabolism. ACS Infect Dis. 2018 07 13; 4(7):1067-1072. Mutch CA, Ordonez AA, Qin H, Parker M, Bambarger LE, Villanueva-Meyer JE, Blecha J, Carroll V, Taglang C, Flavell R, Sriram R, VanBrocklin H, Rosenberg O, Ohliger MA, Jain SK, Neumann KD, Wilson DM. PMID: 29712422; PMCID: PMC6045447.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    97. Discordant Findings on 18F-NaF and 99mTc-HDP Bone Scans in a Patient With ATTR Cardiac Amyloidosis. Clin Nucl Med. 2018 Mar; 43(3):e89-e92. Ng QKT, Sethi P, Saunders TA, Pampaloni MH, Flavell RR. PMID: 29261619.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    98. Cardiac Fibroma: An Uncommon Cause of a Fixed Defect on Myocardial Perfusion Imaging. Clin Nucl Med. 2018 Feb; 43(2):e56-e58. Pittman S, Sethi P, Flavell RR, Pampaloni MH. PMID: 29215416.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    99. Direct assessment of renal mitochondrial redox state using hyperpolarized 13 C-acetoacetate. Magn Reson Med. 2018 04; 79(4):1862-1869. von Morze C, Ohliger MA, Marco-Rius I, Wilson DM, Flavell RR, Pearce D, Vigneron DB, Kurhanewicz J, Wang ZJ. PMID: 29314217; PMCID: PMC5815327.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    100. Scatter Artifact with Ga-68-PSMA-11 PET: Severity Reduced With Furosemide Diuresis and Improved Scatter Correction. Mol Imaging. 2018 Jan-Dec; 17:1536012118811741. Lawhn-Heath C, Flavell RR, Korenchan DE, Deller T, Lake S, Carroll PR, Hope TA. PMID: 31749411; PMCID: PMC6287320.
      View in: PubMed   Mentions: 3     Fields:    
    101. Abnormal pulmonary 18F-florbetapir uptake in a patient evaluated for recurrent cardiac amyloidosis following orthotopic heart transplant. J Nucl Cardiol. 2018 10; 25(5):1865-1868. Pittman S, Sethi P, Flavell RR, De Marco T, Hernandez Pampaloni M. PMID: 29101671.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    102. Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers. Sci Rep. 2017 08 11; 7(1):7903. Neumann KD, Villanueva-Meyer JE, Mutch CA, Flavell RR, Blecha JE, Kwak T, Sriram R, VanBrocklin HF, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 28801560; PMCID: PMC5554133.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    103. Exploring Metabolism In Vivo Using Endogenous 11C Metabolic Tracers. Semin Nucl Med. 2017 09; 47(5):461-473. Neumann K, Flavell R, Wilson DM. PMID: 28826521; PMCID: PMC6037183.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    104. Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging. Analyst. 2017 May 02; 142(9):1429-1433. Korenchan DE, Taglang C, von Morze C, Blecha JE, Gordon JW, Sriram R, Larson PEZ, Vigneron DB, VanBrocklin HF, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 28322385; PMCID: PMC5462110.
      View in: PubMed   Mentions: 12     Fields:    
    105. Abnormal 18F-FDG and 82Rb PET Findings in Chagas Heart Disease. Clin Nucl Med. 2017 May; 42(5):e265-e268. Salimy MS, Parwani PJ, Mukai K, Pampaloni MH, Flavell RR. PMID: 28263213.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    106. Incidental Detection of Head and Neck Squamous Cell Carcinoma on 68Ga-PSMA-11 PET/CT. Clin Nucl Med. 2017 Apr; 42(4):e218-e220. Lawhn-Heath C, Flavell RR, Glastonbury C, Hope TA, Behr SC. PMID: 28166149.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    107. Somatostatin receptor PET/MRI for the evaluation of neuroendocrine tumors. Clinical and Translational Imaging. 2017 Feb 1; 5(1):63-69. Hope HT, Pampaloni PM, Flavell FR, Nakakura NE, Bergsland BE. .
      View in: Publisher Site   Mentions:
    108. Effect of Time-of-Flight and Regularized Reconstructions on Quantitative Measurements and Qualitative Assessments in Newly Diagnosed Prostate Cancer With 18F-Fluorocholine Dual Time Point PET/MRI. Mol Imaging. 2017 Jan-Dec; 16:1536012117736703. Behr SC, Mollard BJ, Yang J, Flavell RR, Hawkins RA, Seo Y. PMID: 29169313; PMCID: PMC5703093.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    109. Detecting Pulmonary Nodules in Lung Cancer Patients Using Whole Body FDG PET/CT, High-resolution Lung Reformat of FDG PET/CT, or Diagnostic Breath Hold Chest CT. Acad Radiol. 2016 09; 23(9):1123-9. Flavell RR, Behr SC, Mabray MC, Hernandez-Pampaloni M, Naeger DM. PMID: 27283073.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    110. A reactivity-based [18F]FDG probe for in vivo formaldehyde imaging using positron emission tomography. Chem Sci. 2016 Aug 01; 7(8):5503-5507. Liu W, Truillet C, Flavell RR, Brewer TF, Evans MJ, Wilson DM, Chang CJ. PMID: 30034690; PMCID: PMC6021783.
      View in: PubMed   Mentions: 11  
    111. Recent Developments in Combined PET/MRI. Current Radiology Reports. 2016 May 1; 4(5):22. Flavell FR, Wilson WD, Behr BS. .
      View in: Publisher Site   Mentions:
    112. [(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography. Chem Commun (Camb). 2016 Apr 07; 52(27):4888-90. Carroll VN, Truillet C, Shen B, Flavell RR, Shao X, Evans MJ, VanBrocklin HF, Scott PJ, Chin FT, Wilson DM. PMID: 26963495; PMCID: PMC4854297.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    113. Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging. Chem Commun (Camb). 2016 Feb 18; 52(14):3030-3. Korenchan DE, Flavell RR, Baligand C, Sriram R, Neumann K, Sukumar S, VanBrocklin H, Vigneron DB, Wilson DM, Kurhanewicz J. PMID: 26792559; PMCID: PMC4864526.
      View in: PubMed   Mentions: 20     Fields:    
    114. Malignancies with Low Fluorodeoxyglucose Uptake at PET/CT: Pitfalls and Prognostic Importance: Resident and Fellow Education Feature. Radiographics. 2016 Jan-Feb; 36(1):293-4. Flavell RR, Naeger DM, Aparici CM, Hawkins RA, Pampaloni MH, Behr SC. PMID: 26761542; PMCID: PMC4801421.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    115. Caged [(18)F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography. Bioconjug Chem. 2016 Jan 20; 27(1):170-8. Flavell RR, Truillet C, Regan MK, Ganguly T, Blecha JE, Kurhanewicz J, VanBrocklin HF, Keshari KR, Chang CJ, Evans MJ, Wilson DM. PMID: 26649808; PMCID: PMC4854293.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    116. Application of Good's buffers to pH imaging using hyperpolarized (13)C MRI. Chem Commun (Camb). 2015 Sep 25; 51(74):14119-22. Flavell RR, von Morze C, Blecha JE, Korenchan DE, Van Criekinge M, Sriram R, Gordon JW, Chen HY, Subramaniam S, Bok RA, Wang ZJ, Vigneron DB, Larson PE, Kurhanewicz J, Wilson DM. PMID: 26257040; PMCID: PMC4854286.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    117. Predictors of pathologic outcome of focal FDG uptake in the parotid gland identified on whole-body FDG PET imaging. Clin Imaging. 2015 Nov-Dec; 39(6):1073-9. Mabray MC, Behr SC, Naeger DM, Flavell RR, Glastonbury CM. PMID: 26324219; PMCID: PMC4630158.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    118. Abnormal findings on multiparametric prostate magnetic resonance imaging predict subsequent biopsy upgrade in patients with low risk prostate cancer managed with active surveillance. Abdom Imaging. 2014 Oct; 39(5):1027-35. Flavell RR, Westphalen AC, Liang C, Sotto CC, Noworolski SM, Vigneron DB, Wang ZJ, Kurhanewicz J. PMID: 24740760; PMCID: PMC4169752.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    119. The incidence of pulmonary embolism and associated FDG-PET findings in IV contrast-enhanced PET/CT. Acad Radiol. 2014 Jun; 21(6):718-25. Flavell RR, Behr SC, Brunsing RL, Naeger DM, Pampaloni MH. PMID: 24809314.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    120. PET imaging of leptin biodistribution and metabolism in rodents and primates. Cell Metab. 2009 Aug; 10(2):148-59. Ceccarini G, Flavell RR, Butelman ER, Synan M, Willnow TE, Bar-Dagan M, Goldsmith SJ, Kreek MJ, Kothari P, Vallabhajosula S, Muir TW, Friedman JM. PMID: 19656493; PMCID: PMC2867490.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    121. Expressed protein ligation (EPL) in the study of signal transduction, ion conduction, and chromatin biology. Acc Chem Res. 2009 Jan 20; 42(1):107-16. Flavell RR, Muir TW. PMID: 18939858.
      View in: PubMed   Mentions: 42     Fields:    Translation:Cells
    122. Site-specific (18)F-labeling of the protein hormone leptin using a general two-step ligation procedure. J Am Chem Soc. 2008 Jul 16; 130(28):9106-12. Flavell RR, Kothari P, Bar-Dagan M, Synan M, Vallabhajosula S, Friedman JM, Muir TW, Ceccarini G. PMID: 18570424.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    123. Efficient semisynthesis of a tetraphosphorylated analogue of the Type I TGFbeta receptor. Org Lett. 2002 Jan 24; 4(2):165-8. Flavell RR, Huse M, Goger M, Trester-Zedlitz M, Kuriyan J, Muir TW. PMID: 11796041.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells