Shweta Motiwala, MD, MPH

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address505 Parnassus Avenue, #M1177B
San Francisco CA 94117
Pronounsshe/her/hers
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    Collapse Biography 
    Collapse Education and Training
    Harvard College, Cambridge, MAAB2004History and Science
    New York University School of Medicine, New York, NYMD2009Medicine
    Massachusetts General Hospital, Boston, MAResidency2012Internal Medicine
    Beth Israel Deaconess Medical Center, Boston, MAFellowship2016Cardiovascular Disease
    Brigham and Women's Hospital, Boston, MAFellowship2017Advanced Heart Failure and Transplant Cardiology
    Harvard T.H. Chan School of Public Health, Boston, MAMPH2019Clinical Effectiveness
    Collapse Awards and Honors
    Doris Duke Charitable Foundation2007  - 2008Doris Duke Clinical Research Fellowship
    New York University School of Medicine2008Alpha Omega Alpha Honor Society
    New York University School of Medicine2009AMWA Glasgow-Rubin Award (Academic Achievement)
    Massachusetts General Hospital2012  - 2013Dennis and Marilyn Barry Fellowship in Cardiovascular Medicine (Research)
    Beth Israel Deaconess Medical Center2016Gerald E. Altman, MD and Harriet Altman Annual Cardiology Fellow Award (Clinical Excellence)

    Collapse Overview 
    Collapse Overview
    I am an Advanced Heart Failure and Transplant cardiologist, and the Director of Heart Failure Disease Management at UCSF. I have clinical expertise in evaluating and treating patients across the spectrum of heart failure disease severity, including those who require mechanical circulatory support or heart transplantation. I have a particular interest in developing chronic disease management programs to improve clinical outcomes and quality of life in patients with heart failure. These include initiatives to expand the use of remote monitoring technologies and platforms, to optimize the application of guideline-directed medical and device therapy, and to improve access to care and transitions of care.

    My research interests include the use of biomarkers in understanding response to therapy and outcomes in heart failure, evaluation of novel remote monitoring and therapeutic devices, and approaches to improving delivery of care to broad patient populations.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 2024 ACC Expert Consensus Decision Pathway for Treatment of Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2024 Apr 16; 83(15):1444-1488. Maddox TM, Januzzi JL, Allen LA, Breathett K, Brouse S, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Lindenfeld J, Masoudi FA, Motiwala SR, Oliveros E, Walsh MN, Wasserman A, Yancy CW, Youmans QR. PMID: 38466244.
      View in: PubMed   Mentions:    Fields:    
    2. Risk Stratification in Advanced Heart Failure: Can Simple Hemodynamic Indices Replace Comprehensive CPET? JACC Heart Fail. 2024 Feb; 12(2):272-274. Motiwala SR, Nayor M. PMID: 37999666.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Induction immunosuppression and post-transplant diabetes mellitus: a propensity-matched cohort study. Front Endocrinol (Lausanne). 2023; 14:1248940. Gupta SK, Mostofsky E, Motiwala SR, Hage A, Mittleman MA. PMID: 37929038; PMCID: PMC10623448.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Outcomes With Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Suspected Acute Myocarditis: 10-Year Experience From the Extracorporeal Life Support Organization Registry. Circ Heart Fail. 2023 07; 16(7):e010152. Nunez JI, Grandin EW, Reyes-Castro T, Sabe M, Quintero P, Motiwala S, Fleming LM, Sriwattanakomen R, Ho JE, Kennedy K, Tonna JE, Garan AR. PMID: 37345545.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Cardiogenic shock related cardiovascular disease mortality trends in US population: Heart failure vs. acute myocardial infarction as contributing causes. Int J Cardiol. 2022 11 15; 367:45-48. Ghajar A, Ordonez CP, Philips B, Pinzon PQ, Fleming LM, Motiwala SR, Sriwattanakomen R, Ho JE, Grandin EW, Sabe M, Garan AR. PMID: 36002041.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Post-transplant mortality and graft failure after induction immunosuppression among Black heart transplant recipients in the United States. Am J Transplant. 2022 11; 22(11):2586-2597. Salia S, Mostofsky E, Gupta S, Lehman L, Barrera FJ, Liou L, Motiwala SR, Mittleman MA. PMID: 35758522; PMCID: PMC9643611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. 2021 Update to the 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2021 02 16; 77(6):772-810. Writing Committee, Maddox TM, Januzzi JL, Allen LA, Breathett K, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Lindenfeld J, Masoudi FA, Motiwala SR, Oliveros E, Patterson JH, Walsh MN, Wasserman A, Yancy CW, Youmans QR. PMID: 33446410.
      View in: PubMed   Mentions: 275     Fields:    Translation:Humans
    8. From Proteomics to Therapeutics: Sex Differences in Cardiovascular Disease Risk Do Matter. J Am Coll Cardiol. 2019 09 24; 74(12):1554-1556. Motiwala SR. PMID: 31537264.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. A clinical and proteomics approach to predict the presence of obstructive peripheral arterial disease: From the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) Study. Clin Cardiol. 2018 Jul; 41(7):903-909. McCarthy CP, Ibrahim NE, van Kimmenade RRJ, Gaggin HK, Simon ML, Gandhi P, Kelly N, Motiwala SR, Mukai R, Magaret CA, Barnes G, Rhyne RF, Garasic JM, Januzzi JL. PMID: 29876944; PMCID: PMC6489776.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    10. Single-Molecule Counting of High-Sensitivity Troponin I in Patients Referred for Diagnostic Angiography: Results From the CASABLANCA (Catheter Sampled Blood Archive in Cardiovascular Diseases) Study. J Am Heart Assoc. 2018 03 08; 7(6). McCarthy CP, Ibrahim NE, Lyass A, Li Y, Gaggin HK, Simon ML, Mukai R, Gandhi P, Kelly N, Motiwala SR, van Kimmenade RRJ, Massaro JM, D'Agostino RB, Januzzi JL. PMID: 29519811; PMCID: PMC5907559.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    11. Predicting new-onset HF in patients undergoing coronary or peripheral angiography: results from the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) study. ESC Heart Fail. 2018 06; 5(3):240-248. Ibrahim NE, Lyass A, Gaggin HK, Liu Y, van Kimmenade RRJ, Motiwala SR, Kelly NP, Gandhi PU, Simon ML, Belcher AM, Harisiades JE, Massaro JM, D'Agostino RB, Januzzi JL. PMID: 29424480; PMCID: PMC5933950.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. J Am Coll Cardiol. 2018 01 16; 71(2):201-230. Yancy CW, Januzzi JL, Allen LA, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Jessup M, Lindenfeld J, Maddox TM, Masoudi FA, Motiwala SR, Patterson JH, Walsh MN, Wasserman A. PMID: 29277252.
      View in: PubMed   Mentions: 90     Fields:    Translation:Humans
    13. Systematic Evaluation of Endothelin 1 Measurement Relative to Traditional and Modern Biomarkers for Clinical Assessment and Prognosis in Patients With Chronic Systolic Heart Failure: Serial Measurement and Multimarker Testing. Am J Clin Pathol. 2017 May 01; 147(5):461-472. Gaggin HK, Truong QA, Gandhi PU, Motiwala SR, Belcher AM, Weiner RB, Baggish AL, Januzzi JL. PMID: 28398455.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    14. Usefulness of Multiple Biomarkers for Predicting Incident Major Adverse Cardiac Events in Patients Who Underwent Diagnostic Coronary Angiography (from the Catheter Sampled Blood Archive in Cardiovascular Diseases [CASABLANCA] Study). Am J Cardiol. 2017 07 01; 120(1):25-32. McCarthy CP, van Kimmenade RRJ, Gaggin HK, Simon ML, Ibrahim NE, Gandhi P, Kelly N, Motiwala SR, Belcher AM, Harisiades J, Magaret CA, Rhyne RF, Januzzi JL. PMID: 28487034.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    15. Associations Between Psychological Constructs and Cardiac Biomarkers After Acute Coronary Syndrome. Psychosom Med. 2017 Apr; 79(3):318-326. Celano CM, Beale EE, Beach SR, Belcher AM, Suarez L, Motiwala SR, Gandhi PU, Gaggin H, Januzzi JL, Healy BC, Huffman JC. PMID: 27749683; PMCID: PMC5373993.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    16. A Clinical and Biomarker Scoring System to Predict the Presence of Obstructive Coronary Artery Disease. J Am Coll Cardiol. 2017 Mar 07; 69(9):1147-1156. Ibrahim NE, Januzzi JL, Magaret CA, Gaggin HK, Rhyne RF, Gandhi PU, Kelly N, Simon ML, Motiwala SR, Belcher AM, van Kimmenade RRJ. PMID: 28254177.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    17. Native T1 value in the remote myocardium is independently associated with left ventricular dysfunction in patients with prior myocardial infarction. J Magn Reson Imaging. 2017 10; 46(4):1073-1081. Nakamori S, Alakbarli J, Bellm S, Motiwala SR, Addae G, Manning WJ, Nezafat R. PMID: 28152237; PMCID: PMC5599253.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Incident Type 2 Myocardial Infarction in a Cohort of Patients Undergoing Coronary or Peripheral Arterial Angiography. Circulation. 2017 Jan 10; 135(2):116-127. Gaggin HK, Liu Y, Lyass A, van Kimmenade RR, Motiwala SR, Kelly NP, Mallick A, Gandhi PU, Ibrahim NE, Simon ML, Bhardwaj A, Belcher AM, Harisiades JE, Massaro JM, D'Agostino RB, Januzzi JL. PMID: 27881568.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    19. Biomarkers to Predict Reverse Remodeling and Myocardial Recovery in Heart Failure. Curr Heart Fail Rep. 2016 10; 13(5):207-218. Motiwala SR, Gaggin HK. PMID: 27726056.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    20. Effects of Optimism and Gratitude on Physical Activity, Biomarkers, and Readmissions After an Acute Coronary Syndrome: The Gratitude Research in Acute Coronary Events Study. Circ Cardiovasc Qual Outcomes. 2016 Jan; 9(1):55-63. Huffman JC, Beale EE, Celano CM, Beach SR, Belcher AM, Moore SV, Suarez L, Motiwala SR, Gandhi PU, Gaggin HK, Januzzi JL. PMID: 26646818; PMCID: PMC4720551.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    21. Design and baseline data from the Gratitude Research in Acute Coronary Events (GRACE) study. Contemp Clin Trials. 2015 Sep; 44:11-19. Huffman JC, Beale EE, Beach SR, Celano CM, Belcher AM, Moore SV, Suarez L, Gandhi PU, Motiwala SR, Gaggin H, Januzzi JL. PMID: 26166171; PMCID: PMC4707130.
      View in: PubMed   Mentions: 9     Fields:    
    22. Assessment of mitral valve disease: a review of imaging modalities. Curr Treat Options Cardiovasc Med. 2015 Jul; 17(7):390. Motiwala SR, Delling FN. PMID: 25981195.
      View in: PubMed   Mentions: 5  
    23. Concentrations of highly sensitive cardiac troponin-I predict poor cardiovascular outcomes and adverse remodeling in chronic heart failure. J Cardiovasc Transl Res. 2015 Apr; 8(3):164-72. Motiwala SR, Gaggin HK, Gandhi PU, Belcher A, Weiner RB, Baggish AL, Szymonifka J, Januzzi JL. PMID: 25777344.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    24. Comparison between admission natriuretic peptides, NGAL and sST2 testing for the prediction of worsening renal function in patients with acutely decompensated heart failure. Clin Chem Lab Med. 2015 Mar; 53(4):613-21. De Berardinis B, Gaggin HK, Magrini L, Belcher A, Zancla B, Femia A, Simon M, Motiwala S, Bhardwaj A, Parry BA, Nagurney JT, Coudriou C, Legrand M, Sadoune M, Di Somma S, Januzzi JL, Global Research on Acute Conditions Team (GREAT). PMID: 25473804.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Galectin-3 and mineralocorticoid receptor antagonist use in patients with chronic heart failure due to left ventricular systolic dysfunction. Am Heart J. 2015 Mar; 169(3):404-411.e3. Gandhi PU, Motiwala SR, Belcher AM, Gaggin HK, Weiner RB, Baggish AL, Fiuzat M, Brunner-La Rocca HP, Januzzi JL. PMID: 25728731.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    26. Evidence of uncoupling between renal dysfunction and injury in cardiorenal syndrome: insights from the BIONICS study. PLoS One. 2014; 9(11):e112313. Legrand M, De Berardinis B, Gaggin HK, Magrini L, Belcher A, Zancla B, Femia A, Simon M, Motiwala S, Sambhare R, Di Somma S, Mebazaa A, Vaidya VS, Januzzi JL, Global Research on Acute Conditions Team (GREAT). PMID: 25386851; PMCID: PMC4227686.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    27. ST2 pathogenetic profile in ambulatory heart failure patients. J Card Fail. 2015 Apr; 21(4):355-61. Bayes-Genis A, Januzzi JL, Gaggin HK, de Antonio M, Motiwala SR, Zamora E, Galán A, Domingo M, Urrutia A, Lupón J. PMID: 25451702.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    28. Characterization and prediction of adverse events from intensive chronic heart failure management and effect on quality of life: results from the pro-B-type natriuretic peptide outpatient-tailored chronic heart failure therapy (PROTECT) study. J Card Fail. 2015 Jan; 21(1):9-15. Gandhi PU, Szymonifka J, Motiwala SR, Belcher AM, Januzzi JL, Gaggin HK. PMID: 25463415.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Prognostic usefulness of insulin-like growth factor-binding protein 7 in heart failure with reduced ejection fraction: a novel biomarker of myocardial diastolic function? Am J Cardiol. 2014 Nov 15; 114(10):1543-9. Gandhi PU, Gaggin HK, Sheftel AD, Belcher AM, Weiner RB, Baggish AL, Motiwala SR, Liu PP, Januzzi JL. PMID: 25248814.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    30. Head-to-head comparison of serial soluble ST2, growth differentiation factor-15, and highly-sensitive troponin T measurements in patients with chronic heart failure. JACC Heart Fail. 2014 Feb; 2(1):65-72. Gaggin HK, Szymonifka J, Bhardwaj A, Belcher A, De Berardinis B, Motiwala S, Wang TJ, Januzzi JL. PMID: 24622120.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    31. Measurement of novel biomarkers to predict chronic heart failure outcomes and left ventricular remodeling. J Cardiovasc Transl Res. 2014 Mar; 7(2):250-61. Motiwala SR, Szymonifka J, Belcher A, Weiner RB, Baggish AL, Gaggin HK, Bhardwaj A, Januzzi JL. PMID: 24309956.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    32. Biomarkers in ACS and heart failure: should men and women be interpreted differently? Clin Chem. 2014 Jan; 60(1):35-43. Motiwala SR, Sarma A, Januzzi JL, O'Donoghue ML. PMID: 24255075.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    33. Soluble concentrations of the interleukin receptor family member ST2 and β-blocker therapy in chronic heart failure. Circ Heart Fail. 2013 Nov; 6(6):1206-13. Gaggin HK, Motiwala S, Bhardwaj A, Parks KA, Januzzi JL. PMID: 24114865.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    34. Serial measurement of galectin-3 in patients with chronic heart failure: results from the ProBNP Outpatient Tailored Chronic Heart Failure Therapy (PROTECT) study. Eur J Heart Fail. 2013 Oct; 15(10):1157-63. Motiwala SR, Szymonifka J, Belcher A, Weiner RB, Baggish AL, Sluss P, Gaggin HK, Bhardwaj A, Januzzi JL. PMID: 23666680.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    35. Using biomarkers to "guide" heart failure management: current perspectives and future directions. Cardiol Rev. 2013 May-Jun; 21(3):127-34. Motiwala SR, Januzzi JL. PMID: 23032578.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Depression and cardiac disease: epidemiology, mechanisms, and diagnosis. Cardiovasc Psychiatry Neurol. 2013; 2013:695925. Huffman JC, Celano CM, Beach SR, Motiwala SR, Januzzi JL. PMID: 23653854; PMCID: PMC3638710.
      View in: PubMed   Mentions: 131  
    37. The role of natriuretic peptides as biomarkers for guiding the management of chronic heart failure. Clin Pharmacol Ther. 2013 Jan; 93(1):57-67. Motiwala SR, Januzzi JL. PMID: 23187878.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    38. Vitamin D and cardiovascular risk. Curr Hypertens Rep. 2012 Jun; 14(3):209-18. Motiwala SR, Wang TJ. PMID: 22457243.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    39. Vitamin D and cardiovascular disease. Curr Opin Nephrol Hypertens. 2011 Jul; 20(4):345-53. Motiwala SR, Wang TJ. PMID: 21519252.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
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