Lucas Zier, MD

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Avenue, #5G02
San Francisco CA 94110
ORCID ORCID Icon0000-0002-3879-5529 Additional info
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    University of California, San FranciscoM.D.2009 Medicine
    University of California, San FranciscoM.S.2007 Medicine

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A CUSTOM POINT OF CARE, DIGITALLY INTEGRATED, DECISION SUPPORT TOOL INCREASES GUIDELINE-DIRECTED HEART FAILURE MEDICATION UTILIZATION IN A SAFETY-NET SYSTEM. Journal of the American College of Cardiology. 2025 Apr 1; 85(12):2832. Davis DJ, Bennett BD, Kothari KA, Feng FJ, Zier ZL. .
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    2. EARLY RESULTS OF THE COMBO-HF-X PILOT CROSSOVER TRIAL: DELIVERING QUADRUPLE THERAPY FOR HEART FAILURE WITH REDUCED EJECTION FRACTION IN A SINGLE CAPSULE IN A SAFETY NET HEALTHCARE SYSTEM. Journal of the American College of Cardiology. 2025 Apr 1; 85(12):1517. DeJong DC, Durstenfeld DM, Davis DJ, Wang WC, Levkova LM, Schaffer SV, Riley RE, Huffman HM, Hickey HM, Shade SS, Chen CJ, Steward SW, Kazi KD, Grochowski GJ, Zier ZL, Moreau MN, Sandhu SA, Heidenreich HP, Agarwal AA, Hsue HP. .
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    3. Prototyping and Manufacturing of Customized Over-Encapsulated Polypills for Heart Failure With Reduced Ejection Fraction in a Safety-Net Health Care System. J Card Fail. 2025 May; 31(5):868-871. Dejong C, Durstenfeld MS, Davis JD, Wang CS, Chen JC, Kazi DS, Hickey MD, Grochowski J, Steward WT, Riley ED, Zier LS, Moreau N, Huffman MD, Sandhu AT, Heidenreich PA, Agarwal A, Hsue PY. PMID: 40169092.
      View in: PubMed   Mentions:    Fields:    
    4. Delivering guideline-directed medical therapy for heart failure with reduced ejection fraction as an over-encapsulated polypill: rationale and protocol for the COMBO-HF-X pilot crossover randomised clinical trial. BMJ Open. 2025 Mar 21; 15(3):e093663. DeJong C, Durstenfeld MS, Davis JD, Wang CS, Riley ED, Huffman MD, Hickey MD, Shade SB, Chen JC, Kazi DS, Grochowski J, Steward WT, Zier LS, Moreau N, Sandhu AT, Heidenreich PA, Agarwal A, Hsue PY. PMID: 40118491; PMCID: PMC11950958.
      View in: PubMed   Mentions:    Fields:    Translation:CTClinical Trials
    5. Reducing readmissions in the safety net through AI and automation. Am J Manag Care. 2025 Mar; 31(3):142-148. Bennett DJ, Feng J, Goldman S, Kothari A, Gottlieb LM, Durstenfeld MS, Marks J, Ehrlich S, Davis J, Zier LS. PMID: 40053406.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Association Between Coronary Assessment in Heart Failure and Clinical Outcomes Within a Safety-Net Setting Using a Target Trial Emulation Observational Design. Circ Cardiovasc Qual Outcomes. 2024 Jun; 17(6):e010800. Durstenfeld MS, Thakkar A, Ma Y, Zier LS, Davis JD, Hsue PY. PMID: 38682336; PMCID: PMC11187668.
      View in: PubMed   Mentions: 1     Fields:    
    7. Predictors of All-Cause 30-Day Readmissions in Patients with Heart Failure at an Urban Safety Net Hospital: The Importance of Social Determinants of Health and Mental Health. Am J Med Open. 2023 Dec; 10:100060. Steverson AB, Marano PJ, Chen C, Ma Y, Stern RJ, Feng J, Gennatas ED, Marks JD, Durstenfeld MS, Davis JD, Hsue PY, Zier LS. PMID: 39035237; PMCID: PMC11256223.
      View in: PubMed   Mentions: 1  
    8. Coronary Assessment in Heart Failure within a Safety-Net Setting: Disparities and Outcomes. medRxiv. 2023 Jul 08. Durstenfeld MS, Thakkar A, Ma Y, Zier LS, Davis JD, Hsue PY. PMID: 37461492; PMCID: PMC10350143.
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    9. Echocardiographic estimation of pulmonary vascular resistance in advanced lung disease. Pulm Circ. 2023 Jan; 13(1):e12183. DesJardin JT, Svetlichnaya Y, Kolaitis NA, Hays SR, Kukreja J, Schiller NB, Zier LS, Singer JP, De Marco T. PMID: 36618711; PMCID: PMC9817072.
      View in: PubMed   Mentions: 1  
    10. Heparin Does Not Regulate Circulating Human PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) in a General Population-Brief Report. Arterioscler Thromb Vasc Biol. 2023 02; 43(2):352-358. Xia VQ, Ong CM, Zier LS, MacGregor JS, Wu AHB, Chorba JS. PMID: 36475702; PMCID: PMC10038152.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    11. Abstract 11069: Evaluation for Ischemic Cardiomyopathy After Heart Failure Diagnosis is Associated With Reduced Mortality in a Safety-Net Setting. Circulation. 2022 Nov 8; 146(Suppl_1):a11069-a11069. Durstenfeld DM, Thakkar TA, Ma MY, Zier ZL, Davis DJ, Hsue HP. .
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    12. Effect of a Novel, Evidence-Based, Standardized Discharge Checklist on 30-Day All-Cause Readmissions in Patients Hospitalized for Heart Failure in an Urban Safety Net Hospital. Am J Cardiol. 2022 11 01; 182:40-45. Marano PJ, Steverson AB, Chen C, Ma Y, Stern RJ, Davis J, Hsue PY, Zier LS. PMID: 36028389.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. An unexpected turn: A 71-year-old man with myocardial infarction. Cleve Clin J Med. 2022 07 01; 89(7):401-407. Ganeshan S, Kelemen B, Dhaliwal G, Zier L. PMID: 35777842.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Hearts and Minds: an Exercise in Clinical Reasoning. J Gen Intern Med. 2021 06; 36(6):1778-1783. Mayfield JJ, McKee KY, Zier LS, Kohlwes RJ. PMID: 33765236; PMCID: PMC8175678.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Pregnancy-Associated Chest Pain: A Case of Spontaneous Coronary Artery Dissection. Case Rep Cardiol. 2021; 2021:4057182. Yogeswaran V, Ramakrishna S, MacGregor JS, Zier L, Goldschlager N. PMID: 33510913; PMCID: PMC7822652.
      View in: PubMed   Mentions: 1  
    16. Abstract 16520: Predictors of Thirty Day Readmission in a Vulnerable and Underserved Urban Heart Failure Population. Circulation. 2020 Nov 17; 142(Suppl_3). Steverson SA, Marano MP, Chen CC, Ma MY, Stern SR, Davis DJ, Hsue HP, Zier ZL. .
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    17. Abstract 13880: A Novel, Evidence-based, Standardized Discharge Checklist Reduces Thirty Day Heart Failure Readmissions in an Urban Safety Net Hospital. Circulation. 2020 Nov 17; 142(Suppl_3). Marano MP, Steverson SA, Chen CC, Ma MY, Stern SR, Davis DJ, Hsue HP, Zier ZL. .
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    18. Noninvasive estimation of pulmonary vascular resistance improves portopulmonary hypertension screening in liver transplant candidates. Clin Transplant. 2019 07; 33(7):e13585. DesJardin JT, Manicardi M, Svetlichnaya Y, Kolaitis NA, Papolos AI, Selby VN, Zier LS, Klein L, Aras MA, Yao FY, Roberts JP, De Marco T. PMID: 31074522.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Successful Use of Pulmonary Vasodilators in Acute Chest Syndrome Complicated by Persistent Right Ventricular Failure. Case Rep Cardiol. 2019; 2019:4681392. DesJardin JT, Zier LS. PMID: 31149361; PMCID: PMC6501236.
      View in: PubMed   Mentions: 2  
    20. Cardiopulmonary exercise testing in the evaluation of liver disease in adults who have had the Fontan operation. Arch Cardiovasc Dis. 2018 Apr; 111(4):276-284. Agarwal A, Cunnington C, Sabanayagam A, Zier L, McCulloch CE, Harris IS, Foster E, Atkinson D, Bryan A, Jenkins P, Dua J, Parker MJ, Karunaratne D, Moore JA, Meadows J, Clarke B, Hoschtitzky JA, Mahadevan VS. PMID: 29198937.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. PREVALENCE OF ELEVATED BODY MASS INDEX AND ITS ASSOCIATION WITH CLINICAL FEATURES IN ADULT FONTAN PATIENTS. Journal of the American College of Cardiology. 2017 Mar 1; 69(11):631. Agarwal AA, Sabanayagam SA, Kheiwa KA, Cunnington CC, Zier ZL, McCulloch MC, Harris HI, Foster FE, Atkinson AD, Bryan BA, Jenkins JP, Dua DJ, Parker PM, Karunaratne KD, Moore MJ, Meadows MJ, Clarke CB, Hoschtitzky HJ, Mahadevan MV. .
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    22. PREVALENCE AND PREDICTORS OF ATRIAL TACHYARRHYTHMIAS IN ADULT FONTAN PATIENTS. Journal of the American College of Cardiology. 2017 Mar 1; 69(11):602. Agarwal AA, Sabanayagam SA, Kheiwa KA, Cunnington CC, Harris HI, Gerstenfeld GE, McCulloch MC, Foster FE, Tseng TZ, Zier ZL, Jenkins JP, Dua DJ, Karunaratne KD, Muhyaldeen MS, Zaidi ZA, Fitzpatrick FA, Garratt GC, Clarke CB, Hoschtitzky HA, Mahadevan MV. .
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    23. TRANSCATHETER CLOSURE OF RESIDUAL LEFT ATRIAL APPENDAGE LEAKS FOLLOWING LARIAT DEVICE CLOSURE. Journal of the American College of Cardiology. 2017 Mar 1; 69(11):432. Singh SS, Zier ZL, Badhwar BN, Lee LR, Mahadevan MV. .
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    24. To close or not to close: contemporary indications for patent foramen ovale closure. Expert Rev Cardiovasc Ther. 2016 Nov; 14(11):1235-1244. Zier LS, Sievert H, Mahadevan VS. PMID: 27616622.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Abstract 17289: A Baffling Heart: a 30 Year-old Man with Biventricular Heart Failure and Severe Pulmonary Hypertension. Circulation. 2014 Nov 25; 130(suppl_2). Zier ZL, Barnett BC, Foster FE. .
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    26. Surrogate decision makers' interpretation of prognostic information: a mixed-methods study. Ann Intern Med. 2012 Mar 06; 156(5):360-6. Zier LS, Sottile PD, Hong SY, Weissfield LA, White DB. PMID: 22393131; PMCID: PMC3530840.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    27. Resolving Conflicts With Surrogate Decision Makers: Response. CHEST Journal. 2010 Jan 1; 137(1):239. Zier ZL, White WD. .
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    28. Surrogate decision makers' responses to physicians' predictions of medical futility. Chest. 2009 Jul; 136(1):110-117. Zier LS, Burack JH, Micco G, Chipman AK, Frank JA, White DB. PMID: 19318665; PMCID: PMC2716715.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    29. Doubt and belief in physicians' ability to prognosticate during critical illness: the perspective of surrogate decision makers. Crit Care Med. 2008 Aug; 36(8):2341-7. Zier LS, Burack JH, Micco G, Chipman AK, Frank JA, Luce JM, White DB. PMID: 18596630; PMCID: PMC2628287.
      View in: PubMed   Mentions: 46     Fields:    
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