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Terumi Kohwi-Shigematsu, PhD

Title(s)Professor, Orofacial Sciences
SchoolSchool of Dentistry
Phone415-502-7828
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yasuda K, Kitagawa Y, Kawakami R, Isaka Y, Watanabe H, Kondoh G, Kohwi-Shigematsu T, Sakaguchi S, Hirota K. Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation. Nat Commun. 2019 02 01; 10(1):549. PMID: 30710091.
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    2. Doi Y, Yokota T, Satoh Y, Okuzaki D, Tokunaga M, Ishibashi T, Sudo T, Ueda T, Shingai Y, Ichii M, Tanimura A, Ezoe S, Shibayama H, Kohwi-Shigematsu T, Takeda J, Oritani K, Kanakura Y. Variable SATB1 Levels Regulate Hematopoietic Stem Cell Heterogeneity with Distinct Lineage Fate. Cell Rep. 2018 06 12; 23(11):3223-3235. PMID: 29898394.
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    3. I. Malashchuk, J. Rudolf, T. Vafaee, K. Poterlowicz, A. Sharov, M. Fessing, T. Kohwi-Shigematsu, G. Xu, A. Mardaryev, V. Botchkarev. 671 Cross-talk between covalent DNA modifications and chromatin architecture: DNA dioxygenase Tet2 mediates the effects of chromatin architectural protein CTCF on epidermal barrier maintenance, inflammation and tumorigenesis. Journal of Investigative Dermatology. 2018 May 1; 138(5):s114.
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    4. Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S. Addendum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Nat Immunol. 2017 10 18; 18(11):1270. PMID: 29044238.
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    5. K. Poterlowicz, J. Yarker, I. Malashchuk, A.N. Mardaryev, M.R. Gdula, A. sharov, T. Kohwi-Shigematsu, V. Botchkarev, M.Y. Fessing. 091 5C analysis reveals distinct spatial contact networks between gene-rich and gene-poor TADs at the Epidermal Differentiation Complex in skin epithelial cells. Journal of Investigative Dermatology. 2017 Oct 1; 137(10):s208.
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    6. Poterlowicz K, Yarker JL, Malashchuk I, Lajoie BR, Mardaryev AN, Gdula MR, Sharov AA, Kohwi-Shigematsu T, Botchkarev VA, Fessing MY. 5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells. PLoS Genet. 2017 Sep; 13(9):e1006966. PMID: 28863138.
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    7. Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S. Erratum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Nat Immunol. 2017 03 22; 18(4):474. PMID: 28323270.
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    8. Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S. Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Nat Immunol. 2017 02; 18(2):173-183. PMID: 27992401.
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    9. Yukiko Doi, Takafumi Yokota, Yusuke Satoh, Tomoaki Ueda, Yasuhiro Shingai, Michiko Ichii, Akira Tanimura, Sachiko Ezoe, Hirohiko Shibayama, Kenji Oritani, Terumi Kohwi-Shigematsu, Yuzuru Kanakura. SATB1 Expression Helps in Identification of the Lymphoid-Lineage-Biased Trajectory of Functionally Fluctuating Hematopoietic Stem Cells. Blood. 2016 Dec 2; 128(22):424-424.
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    10. Hilde KL, Levine AJ, Hinckley CA, Hayashi M, Montgomery JM, Gullo M, Driscoll SP, Grosschedl R, Kohwi Y, Kohwi-Shigematsu T, Pfaff SL. Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position. Neuron. 2016 Aug 17; 91(4):763-776. PMID: 27478017.
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    11. Kondo M, Tanaka Y, Kuwabara T, Naito T, Kohwi-Shigematsu T, Watanabe A. Correction: SATB1 Plays a Critical Role in Establishment of Immune Tolerance. J Immunol. 2016 Apr 15; 196(8):3495. PMID: 27044637.
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    12. Kondo M, Tanaka Y, Kuwabara T, Naito T, Kohwi-Shigematsu T, Watanabe A. SATB1 Plays a Critical Role in Establishment of Immune Tolerance. J Immunol. 2016 Jan 15; 196(2):563-72. PMID: 26667169.
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    13. Hao B, Naik AK, Watanabe A, Tanaka H, Chen L, Richards HW, Kondo M, Taniuchi I, Kohwi Y, Kohwi-Shigematsu T, Krangel MS. An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development. J Exp Med. 2015 May 04; 212(5):809-24. PMID: 25847946.
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    14. Skowronska-Krawczyk D, Ma Q, Schwartz M, Scully K, Li W, Liu Z, Taylor H, Tollkuhn J, Ohgi KA, Notani D, Kohwi Y, Kohwi-Shigematsu T, Rosenfeld MG. Required enhancer-matrin-3 network interactions for a homeodomain transcription program. Nature. 2014 Oct 09; 514(7521):257-61. PMID: 25119036.
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    15. Satoh Y, Yokota T, Sudo T, Kondo M, Lai A, Kincade PW, Kouro T, Iida R, Kokame K, Miyata T, Habuchi Y, Matsui K, Tanaka H, Matsumura I, Oritani K, Kohwi-Shigematsu T, Kanakura Y. The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages. Immunity. 2013 Jun 27; 38(6):1105-15. PMID: 23791645.
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    16. Ordinario E, Han HJ, Furuta S, Heiser LM, Jakkula LR, Rodier F, Spellman PT, Campisi J, Gray JW, Bissell MJ, Kohwi Y, Kohwi-Shigematsu T. ATM suppresses SATB1-induced malignant progression in breast epithelial cells. PLoS One. 2012; 7(12):e51786. PMID: 23251624.
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    17. Srinivasan K, Leone DP, Bateson RK, Dobreva G, Kohwi Y, Kohwi-Shigematsu T, Grosschedl R, McConnell SK. A network of genetic repression and derepression specifies projection fates in the developing neocortex. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):19071-8. PMID: 23144223.
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    18. Kohwi-Shigematsu T, Kohwi Y, Takahashi K, Richards HW, Ayers SD, Han HJ, Cai S. SATB1-mediated functional packaging of chromatin into loops. Methods. 2012 Nov; 58(3):243-54. PMID: 22782115.
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    19. Kohwi-Shigematsu T, Poterlowicz K, Ordinario E, Han HJ, Botchkarev VA, Kohwi Y. Genome organizing function of SATB1 in tumor progression. Semin Cancer Biol. 2013 Apr; 23(2):72-9. PMID: 22771615.
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    20. Yusuke Satoh, Takafumi Yokota, Motonari Kondo, Paul W. Kincade, Taku Kouro, Ryuji Iida, Koichi Kokame, Toshiyuki Miyata, Takao Sudo, Hirokazu Tanaka, Itaru Matsumura, Kenji Oritani, Terumi Kohwi-Shigematsu, Yuzuru Kanakura. Satb1 Determines Hematopoietic Stem Cell Differentiation Toward the Lymphoid Lineages. Blood. 2011 Nov 18; 118(21):388-388.
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    21. Balamotis MA, Tamberg N, Woo YJ, Li J, Davy B, Kohwi-Shigematsu T, Kohwi Y. Satb1 ablation alters temporal expression of immediate early genes and reduces dendritic spine density during postnatal brain development. Mol Cell Biol. 2012 Jan; 32(2):333-47. PMID: 22064485.
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    22. H Richards, T Kohwi-Shigematsu. SATB1 (SATB homeobox 1). Atlas of Genetics and Cytogenetics in Oncology and Haematology. 2011 Nov 1; (5).
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    23. Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA. p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19; 194(6):825-39. PMID: 21930775.
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    24. Kohwi-Shigematsu T, Han HJ, Russo J, Kohwi Y. Re: The role of SATB1 in breast cancer pathogenesis. J Natl Cancer Inst. 2010 Dec 15; 102(24):1879-80; author reply 1880-1. PMID: 21076049.
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    25. Savarese F, Dávila A, Nechanitzky R, De La Rosa-Velazquez I, Pereira CF, Engelke R, Takahashi K, Jenuwein T, Kohwi-Shigematsu T, Fisher AG, Grosschedl R. Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression. Genes Dev. 2009 Nov 15; 23(22):2625-38. PMID: 19933152.
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    26. Agrelo R, Souabni A, Novatchkova M, Haslinger C, Leeb M, Komnenovic V, Kishimoto H, Gresh L, Kohwi-Shigematsu T, Kenner L, Wutz A. SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells. Dev Cell. 2009 Apr; 16(4):507-16. PMID: 19386260.
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    27. Russo J, Han HJ, Kohwi Y, Kohwi-Shigematsu T. New advances in breast cancer metastasis. Womens Health (Lond). 2008 Nov; 4(6):547-9. PMID: 19072455.
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    28. Miyano M, Horike S, Cai S, Oshimura M, Kohwi-Shigematsu T. DLX5 expression is monoallelic and Dlx5 is up-regulated in the Mecp2-null frontal cortex. J Cell Mol Med. 2008 Aug; 12(4):1188-91. PMID: 18537997.
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    29. Han HJ, Russo J, Kohwi Y, Kohwi-Shigematsu T. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature. 2008 Mar 13; 452(7184):187-93. PMID: 18337816.
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    30. Ulrich Steidl, Christian Steidl, Alexander Ebralidze, Bjoern Chapuy, Hye-Jung Han, Britta Will, Frank Rosenbauer, Annegret Becker, Katharina Wagner, Steffen Koschmieder, Susumu Kobayashi, Daniel B. Costa, Thomas Schulz, Karen B. O’Brien, Roel G.W. Verhaak, Ruud Delwel, Detlef Haase, Lorenz Trumper, Juergen Krauter, Terumi Kohwi-Shigematsu, Frank Griesinger, Daniel G. Tenen. A Distal Single Nucleotide Polymorphism Disrupts Development-Dependent Long-Range Transcriptional Regulation of the PU.1 Gene through the Chromatin-Remodeling Protein SATB1 in Acute Myeloid Leukemia. Blood. 2007 Nov 16; 110(11):3175-3175.
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    31. Steidl U, Steidl C, Ebralidze A, Chapuy B, Han HJ, Will B, Rosenbauer F, Becker A, Wagner K, Koschmieder S, Kobayashi S, Costa DB, Schulz T, O'Brien KB, Verhaak RG, Delwel R, Haase D, Trümper L, Krauter J, Kohwi-Shigematsu T, Griesinger F, Tenen DG. A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia. J Clin Invest. 2007 Sep; 117(9):2611-20. PMID: 17694175.
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    32. Cai S, Lee CC, Kohwi-Shigematsu T. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat Genet. 2006 Nov; 38(11):1278-88. PMID: 17057718.
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    33. Nakayama Y, Mian IS, Kohwi-Shigematsu T, Ogawa T. A nuclear targeting determinant for SATB1, a genome organizer in the T cell lineage. Cell Cycle. 2005 Aug; 4(8):1099-106. PMID: 15970696.
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    34. Wen J, Huang S, Rogers H, Dickinson LA, Kohwi-Shigematsu T, Noguchi CT. SATB1 family protein expressed during early erythroid differentiation modifies globin gene expression. Blood. 2005 Apr 15; 105(8):3330-9. PMID: 15618465.
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    35. Horike S, Cai S, Miyano M, Cheng JF, Kohwi-Shigematsu T. Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet. 2005 Jan; 37(1):31-40. PMID: 15608638.
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    36. Cai S, Han HJ, Kohwi-Shigematsu T. Tissue-specific nuclear architecture and gene expression regulated by SATB1. Nat Genet. 2003 May; 34(1):42-51. PMID: 12692553.
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    37. Liu QY, Ribecco-Lutkiewicz M, Carson C, Testolin L, Bergeron D, Kohwi-Shigematsu T, Walker PR, Sikorska M. Mapping the initial DNA breaks in apoptotic Jurkat cells using ligation-mediated PCR. Cell Death Differ. 2003 Mar; 10(3):278-89. PMID: 12700628.
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    38. Yasui D, Miyano M, Cai S, Varga-Weisz P, Kohwi-Shigematsu T. SATB1 targets chromatin remodelling to regulate genes over long distances. Nature. 2002 Oct 10; 419(6907):641-5. PMID: 12374985.
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    39. Kieffer LJ, Greally JM, Landres I, Nag S, Nakajima Y, Kohwi-Shigematsu T, Kavathas PB. Identification of a candidate regulatory region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind SATB1 and GATA-3. J Immunol. 2002 Apr 15; 168(8):3915-22. PMID: 11937547.
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    40. Terumi Kohwi-Shigematsu, Yoshinori Kohwi. Matrix Attachment Regions. Wiley Encyclopedia of Molecular Medicine. 2002 Jan 15.
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    41. Bischof O, Galande S, Kohwi-Shigematsu T, Campisi J, Dejean A. The Bloom Syndrome Protein BLM Is Selectively Cleaved during Apoptotic Cell Death. ScientificWorldJournal. 2001; 1:34. PMID: 30147470.
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    42. Hawkins SM, Kohwi-Shigematsu T, Skalnik DG. The matrix attachment region-binding protein SATB1 interacts with multiple elements within the gp91phox promoter and is down-regulated during myeloid differentiation. J Biol Chem. 2001 Nov 30; 276(48):44472-80. PMID: 11577075.
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    43. Galande S, Dickinson LA, Mian IS, Sikorska M, Kohwi-Shigematsu T. SATB1 cleavage by caspase 6 disrupts PDZ domain-mediated dimerization, causing detachment from chromatin early in T-cell apoptosis. Mol Cell Biol. 2001 Aug; 21(16):5591-604. PMID: 11463840.
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    44. Bischof O, Galande S, Farzaneh F, Kohwi-Shigematsu T, Campisi J. Selective cleavage of BLM, the bloom syndrome protein, during apoptotic cell death. J Biol Chem. 2001 Apr 13; 276(15):12068-75. PMID: 11154689.
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    45. Oliver Bischof, Sanjeev Galande, Terumi Kohwi-Shigematsu, Judith Campisi, Anne Dejean. THE BLOOM SYNDROME PROTEIN BLM IS SELECTIVELY CLEAVED DURING APOPTOTIC CELL DEATH. The Scientific World JOURNAL. 2001 Jan 1; 1(S3):34-34.
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    46. Hsu HL, Gilley D, Galande SA, Hande MP, Allen B, Kim SH, Li GC, Campisi J, Kohwi-Shigematsu T, Chen DJ. Ku acts in a unique way at the mammalian telomere to prevent end joining. Genes Dev. 2000 Nov 15; 14(22):2807-12. PMID: 11090128.
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    47. Alvarez JD, Yasui DH, Niida H, Joh T, Loh DY, Kohwi-Shigematsu T. The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Genes Dev. 2000 Mar 01; 14(5):521-35. PMID: 10716941.
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    48. Ramakrishnan M, Liu WM, DiCroce PA, Posner A, Zheng J, Kohwi-Shigematsu T, Krontiris TG. Modulated binding of SATB1, a matrix attachment region protein, to the AT-rich sequence flanking the major breakpoint region of BCL2. Mol Cell Biol. 2000 Feb; 20(3):868-77. PMID: 10629043.
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    49. Galande S, Kohwi-Shigematsu T. Linking chromatin architecture to cellular phenotype: BUR-binding proteins in cancer. J Cell Biochem Suppl. 2000; Suppl 35:36-45. PMID: 11389530.
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    50. Galande S, Kohwi-Shigematsu T. Caught in the act: binding of Ku and PARP to MARs reveals novel aspects of their functional interaction. Crit Rev Eukaryot Gene Expr. 2000; 10(1):63-72. PMID: 10813395.
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    51. Liu WM, Guerra-Vladusic FK, Kurakata S, Lupu R, Kohwi-Shigematsu T. HMG-I(Y) recognizes base-unpairing regions of matrix attachment sequences and its increased expression is directly linked to metastatic breast cancer phenotype. Cancer Res. 1999 Nov 15; 59(22):5695-703. PMID: 10582687.
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    52. Cai S, Kohwi-Shigematsu T. Intranuclear relocalization of matrix binding sites during T cell activation detected by amplified fluorescence in situ hybridization. Methods. 1999 Nov; 19(3):394-402. PMID: 10579934.
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    53. Galande S, Kohwi-Shigematsu T. Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences. J Biol Chem. 1999 Jul 16; 274(29):20521-8. PMID: 10400681.
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    54. de Belle I, Cai S, Kohwi-Shigematsu T. The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops. J Cell Biol. 1998 Apr 20; 141(2):335-48. PMID: 9548713.
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    55. Kohwi-Shigematsu T, deBelle I, Dickinson LA, Galande S, Kohwi Y. Identification of base-unpairing region-binding proteins and characterization of their in vivo binding sequences. Methods Cell Biol. 1998; 53:323-54. PMID: 9348515.
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    56. Benham C, Kohwi-Shigematsu T, Bode J. Stress-induced duplex DNA destabilization in scaffold/matrix attachment regions. J Mol Biol. 1997 Nov 28; 274(2):181-96. PMID: 9398526.
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    57. Kohwi-Shigematsu T, Maass K, Bode J. A thymocyte factor SATB1 suppresses transcription of stably integrated matrix-attachment region-linked reporter genes. Biochemistry. 1997 Oct 07; 36(40):12005-10. PMID: 9340009.
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    58. Neri LM, Fackelmayer FO, Zweyer M, Kohwi-Shigematsu T, Martelli AM. Subnuclear localization of S/MAR-binding proteins is differently affected by in vitro stabilization with heat or Cu2+. Chromosoma. 1997 Jul; 106(2):81-93. PMID: 9215557.
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    59. Dickinson LA, Dickinson CD, Kohwi-Shigematsu T. An atypical homeodomain in SATB1 promotes specific recognition of the key structural element in a matrix attachment region. J Biol Chem. 1997 Apr 25; 272(17):11463-70. PMID: 9111059.
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    60. Zweyer M, Riederer BM, Ochs RL, Fackelmayer FO, Kohwi-Shigematsu T, Bareggi R, Narducci P, Martelli AM. Association of nuclear matrix proteins with granular and threaded nuclear bodies in cell lines undergoing apoptosis. Exp Cell Res. 1997 Feb 01; 230(2):325-36. PMID: 9024791.
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    61. Terumi Kohwi-Shigematsu, Yoshinori Kohwi. 4 High Unwinding Capability of Matrix Attachment Regions and ATC-Sequence Context-Specific MAR-Binding Proteins. Nuclear Structure and Gene Expression. 1997 Jan 1; (EMBO J.81989):111-144.
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    62. Neznanov N, Kohwi-Shigematsu T, Oshima RG. Contrasting effects of the SATB1 core nuclear matrix attachment region and flanking sequences of the keratin 18 gene in transgenic mice. Mol Biol Cell. 1996 Apr; 7(4):541-52. PMID: 8730098.
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    63. Yanagisawa J, Ando J, Nakayama J, Kohwi Y, Kohwi-Shigematsu T. A matrix attachment region (MAR)-binding activity due to a p114 kilodalton protein is found only in human breast carcinomas and not in normal and benign breast disease tissues. Cancer Res. 1996 Feb 01; 56(3):457-62. PMID: 8564952.
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    64. Wang B, Dickinson LA, Koivunen E, Ruoslahti E, Kohwi-Shigematsu T. A novel matrix attachment region DNA binding motif identified using a random phage peptide library. J Biol Chem. 1995 Oct 06; 270(40):23239-42. PMID: 7559473.
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    65. Kohwi Y, Kohwi-Shigematsu T. [Biological significance of nuclear matrix attachment regions (MAR) and tissue specific MAR-DNA binding proteins]. Seikagaku. 1995 Sep; 67(9):1115-27. PMID: 8530869.
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    66. Dickinson LA, Kohwi-Shigematsu T. Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential. Mol Cell Biol. 1995 Jan; 15(1):456-65. PMID: 7799955.
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    67. Nakagomi K, Kohwi Y, Dickinson LA, Kohwi-Shigematsu T. A novel DNA-binding motif in the nuclear matrix attachment DNA-binding protein SATB1. Mol Cell Biol. 1994 Mar; 14(3):1852-60. PMID: 8114718.
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    68. Kladde MP, Kohwi Y, Kohwi-Shigematsu T, Gorski J. The non-B-DNA structure of d(CA/TG)n differs from that of Z-DNA. Proc Natl Acad Sci U S A. 1994 Mar 01; 91(5):1898-902. PMID: 8127902.
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    69. Kohwi Y, Wang H, Kohwi-Shigematsu T. A single trinucleotide, 5'AGC3'/5'GCT3', of the triplet-repeat disease genes confers metal ion-induced non-B DNA structure. Nucleic Acids Res. 1993 Dec 11; 21(24):5651-5. PMID: 8284211.
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    70. Kohwi Y, Kohwi-Shigematsu T. Structural polymorphism of homopurine-homopyrimidine sequences at neutral pH. J Mol Biol. 1993 Jun 20; 231(4):1090-101. PMID: 8515467.
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    71. Dickinson LA, Joh T, Kohwi Y, Kohwi-Shigematsu T. A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition. Cell. 1992 Aug 21; 70(4):631-45. PMID: 1505028.
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    72. Kohwi Y, Malkhosyan SR, Kohwi-Shigematsu T. Intramolecular dG.dG.dC triplex detected in Escherichia coli cells. J Mol Biol. 1992 Feb 20; 223(4):817-22. PMID: 1538396.
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    73. Bode J, Kohwi Y, Dickinson L, Joh T, Klehr D, Mielke C, Kohwi-Shigematsu T. Biological significance of unwinding capability of nuclear matrix-associating DNAs. Science. 1992 Jan 10; 255(5041):195-7. PMID: 1553545.
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    74. Kohwi-Shigematsu T, Kohwi Y. Detection of non-B-DNA structures at specific sites in supercoiled plasmid DNA and chromatin with haloacetaldehyde and diethyl pyrocarbonate. Methods Enzymol. 1992; 212:155-80. PMID: 1518447.
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    75. Kohwi Y, Kohwi-Shigematsu T. Altered gene expression correlates with DNA structure. Genes Dev. 1991 Dec; 5(12B):2547-54. PMID: 1752443.
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    76. Kohwi-Shigematsu T, Kohwi Y. Detection of triple-helix related structures adopted by poly(dG)-poly(dC) sequences in supercoiled plasmid DNA. Nucleic Acids Res. 1991 Aug 11; 19(15):4267-71. PMID: 1870980.
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    77. Kohwi-Shigematsu T, Kohwi Y. Torsional stress stabilizes extended base unpairing in suppressor sites flanking immunoglobulin heavy chain enhancer. Biochemistry. 1990 Oct 16; 29(41):9551-60. PMID: 2125477.
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    78. Mielke C, Kohwi Y, Kohwi-Shigematsu T, Bode J. Hierarchical binding of DNA fragments derived from scaffold-attached regions: correlation of properties in vitro and function in vivo. Biochemistry. 1990 Aug 14; 29(32):7475-85. PMID: 2223779.
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    79. Kohwi Y, Kohwi-Shigematsu T. Magnesium ion-dependent triple-helix structure formed by homopurine-homopyrimidine sequences in supercoiled plasmid DNA. Proc Natl Acad Sci U S A. 1988 Jun; 85(11):3781-5. PMID: 3375241.
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    80. Kohwi-Shigematsu T, Scribner N, Kohwi Y. An ultimate chemical carcinogen, N-acetoxy-2-acetylaminofluorene, detects non-B DNA structures that are reactive with chloroacetaldehyde in supercoiled plasmid DNA. Carcinogenesis. 1988 Mar; 9(3):457-61. PMID: 3345584.
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    81. Kohwi-Shigematsu T, Nelson JA. The chemical carcinogen, chloroacetaldehyde, modifies a specific site within the regulatory sequence of human cytomegalovirus major immediate early gene in vivo. Mol Carcinog. 1988; 1(1):20-5. PMID: 2855599.
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    82. Kohwi-Shigematsu T, Manes T, Kohwi Y. Unusual conformational effect exerted by Z-DNA upon its neighboring sequences. Proc Natl Acad Sci U S A. 1987 Apr; 84(8):2223-7. PMID: 3470786.
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    83. Kohwi-Shigematsu T, Kohwi Y. Poly(dG)-poly(dC) sequences, under torsional stress, induce an altered DNA conformation upon neighboring DNA sequences. Cell. 1985 Nov; 43(1):199-206. PMID: 4075394.
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    84. Groudine M, Kohwi-Shigematsu T, Gelinas R, Stamatoyannopoulos G, Papayannopoulou T. Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus. Proc Natl Acad Sci U S A. 1983 Dec; 80(24):7551-5. PMID: 6200877.
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    85. Kohwi-Shigematsu T, Gelinas R, Weintraub H. Detection of an altered DNA conformation at specific sites in chromatin and supercoiled DNA. Proc Natl Acad Sci U S A. 1983 Jul; 80(14):4389-93. PMID: 6308620.
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    86. Mitane Y, Nakanishi M, Tsuboi M, Kohwi-Shigematsu T, Enomoto T, Yamada MA. Hydrogen-exchange study of a nucleosome. FEBS Lett. 1980 Nov 17; 121(1):130-2. PMID: 7461107.
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    87. Kohwi-Shigematsu T, Enomoto T, Yamada MA, Nakanishi M, Tsuboi M. Exposure of DNA bases induced by the interaction of DNA and calf thymus DNA helix-destabilizing protein. Proc Natl Acad Sci U S A. 1978 Oct; 75(10):4689-93. PMID: 216994.
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