Loading...

Todd Margolis, MD, PhD

TitleProfessor Emeritus
SchoolUCSF Chancellor/EVC/FAS
DepartmentProctor Foundation
Address
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPost-Doc Fellow/Scholar1989 Medicine (Ophthalmology)
    University of California, San Francisco Residency School of Medicine
    University of California, San FranciscoM.D.1984 Medicine
    University of California, San FranciscoPh.D.1983 Graduate Division (Anatomy)

    Collapse Overview 
    Collapse Overview
    Margolis, a UCSF professor of ophthalmology, is the director of the Francis I. Proctor Foundation for Research in Ophthalmology at UCSF Medical Center. He is also president of the Association for Research in Vision and Ophthalmology, the world's largest eye and vision research organization, and serves on the National Advisory Eye Council of the National Eye Institute. He received his MD and his PhD degrees in neuroscience at UCSF.


    Collapse Research 
    Collapse Research Activities and Funding
    REGULATION OF HERPES SIMPLEX TYPE 1 INFECTION IN CORNEAL NEURONS
    NIH/NEI R01EY022697Aug 1, 2013 - Jul 31, 2017
    Role: Principal Investigator
    ORIGIN AND MAINTENANCE OF THE OCULAR SURFACE EPITHELIA
    NIH/NEI R01EY022643Aug 1, 2012 - Jun 30, 2016
    Role: Principal Investigator
    OCULAR INFECTION WITH THE HERPES VIRUSES
    NIH/NEI R01EY010008Dec 1, 1993 - Jun 30, 2006
    Role: Principal Investigator
    NEURONAL INVOLVEMENT IN OCULAR HERPETIC DISEASE
    NIH/NEI F32EY006190Aug 6, 1989
    Role: Principal Investigator
    P30 - CENTER CORE GRANT FOR VISION RESEARCH
    NIH/NEI P30EY002162Dec 1, 1977 - Jun 30, 2019
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Jirawison C, Liu Y, Surasit K, Maningding E, Kamphaengkham S, Ausayakhun S, Heiden D, Margolis T, Gonzales JA, Acharya NR, Keenan JD. Fundus findings in a series of patients with extrapulmonary tuberculosis in Thailand. Br J Ophthalmol. 2017 Jun; 101(6):691-694. PMID: 28450377.
      View in: PubMed
    2. Liu Y, Chen AS, Kamphaengkham S, Leenasirimakul P, Jirawison C, Ausayakhun S, Margolis T, Keenan JD. Diagnostic Utility of Ocular Symptoms and Vision for Cytomegalovirus Retinitis. PLoS One. 2016; 11(10):e0165564. PMID: 27788232.
      View in: PubMed
    3. Leenasirimakul P, Liu Y, Jirawison C, Khienprasit N, Kamphaengkham S, Ausayakhun S, Chen J, Yen M, Heiden D, Holland GN, Margolis T, Keenan JD. Risk factors for CMV retinitis among individuals with HIV and low CD4 count in northern Thailand: importance of access to healthcare. Br J Ophthalmol. 2016 Aug; 100(8):1017-21. PMID: 27297217.
      View in: PubMed
    4. Somkijrungroj T, Pimolrat W, Gonzales JA, Keenan JD, Margolis T. Conjunctival Sensation in Scleritis. Ocul Immunol Inflamm. 2016; 24(1):24-8. PMID: 26647348.
      View in: PubMed
    5. Delwig A, Keenan JD, Margolis T. Topical Valganciclovir for the Treatment of Hypertensive Anterior Uveitis. Cornea. 2015 Nov; 34(11):1513-5. PMID: 26356754.
      View in: PubMed
    6. Van Gelder RN, Margolis T. Ebola and the Ophthalmologist. Ophthalmology. 2015 Nov; 122(11):2152-4. PMID: 26498076.
      View in: PubMed
    7. Galor A, Batawi H, Felix ER, Margolis T, Sarantopoulos KD, Martin ER, Levitt RC. Incomplete response to artificial tears is associated with features of neuropathic ocular pain. Br J Ophthalmol. 2016 Jun; 100(6):745-9. PMID: 26377416.
      View in: PubMed
    8. Lin MC, Asbell PA, Margolis T, McNamarra NA, Nichols KK, Nichols JJ, Polse KA. Dry Eye Disease. Optom Vis Sci. 2015 Sep; 92(9):922-4. PMID: 26301366.
      View in: PubMed
    9. Margolis T. Remembering David C. Beebe, PhD, 1944-2015. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4975. PMID: 26230761.
      View in: PubMed
    10. Galor A, Felix ER, Feuer W, Shalabi N, Martin ER, Margolis T, Sarantopoulos CD, Levitt RC. Dry eye symptoms align more closely to non-ocular conditions than to tear film parameters. Br J Ophthalmol. 2015 Aug; 99(8):1126-9. PMID: 25710726.
      View in: PubMed
    11. Tang S, Bosch-Marce M, Patel A, Margolis T, Krause PR. Characterization of herpes simplex virus 2 primary microRNA Transcript regulation. J Virol. 2015 May; 89(9):4837-48. PMID: 25673716; PMCID: PMC4403459.
    12. Jirawison C, Yen M, Leenasirimakul P, Chen J, Guadanant S, Kunavisarut P, Patikulsila D, Watanachai N, Ausayakhun S, Heiden D, Holland GN, Margolis T, Keenan JD. Telemedicine screening for cytomegalovirus retinitis at the point of care for human immunodeficiency virus infection. JAMA Ophthalmol. 2015 Feb; 133(2):198-205. PMID: 25412344.
      View in: PubMed
    13. Yen M, Chen J, Ausayakhun S, Kunavisarut P, Vichitvejpaisal P, Ausayakhun S, Jirawison C, Shantha J, Holland GN, Heiden D, Margolis T, Keenan JD. Retinal detachment associated with AIDS-related cytomegalovirus retinitis: risk factors in a resource-limited setting. Am J Ophthalmol. 2015 Jan; 159(1):185-92. PMID: 25448999; PMCID: PMC4262697.
    14. Stanzel TP, Diaz JD, Mather R, Wong IG, Margolis T, Gritz DC. The epidemiology of herpes simplex virus eye disease in Northern California. Ophthalmic Epidemiol. 2014 Dec; 21(6):370-7. PMID: 25299934.
      View in: PubMed
    15. Yen M, Ausayakhun S, Chen J, Ausayakhun S, Jirawison C, Heiden D, Holland GN, Margolis T, Keenan JD. Telemedicine diagnosis of cytomegalovirus retinitis by nonophthalmologists. JAMA Ophthalmol. 2014 Sep; 132(9):1052-8. PMID: 24945306.
      View in: PubMed
    16. Vo RC, Stafeeva K, Aldave AJ, Stulting RD, Moore Q, Pflugfelder SC, Chungfat NC, Holsclaw DS, Margolis T, Deng SX. Complications related to a cosmetic eye-whitening procedure. Am J Ophthalmol. 2014 Nov; 158(5):967-73. PMID: 25072832.
      View in: PubMed
    17. Maamari RN, Ausayakhun S, Margolis T, Fletcher DA, Keenan JD. Novel telemedicine device for diagnosis of corneal abrasions and ulcers in resource-poor settings. JAMA Ophthalmol. 2014 Jul; 132(7):894-5. PMID: 25010172.
      View in: PubMed
    18. Culican SM, Rupp JD, Margolis T. Retaining clinician-scientists: nature versus nurture. Invest Ophthalmol Vis Sci. 2014 May 27; 55(5):3219-22. PMID: 24867910.
      View in: PubMed
    19. Greene JB, Jeng BH, Fintelmann RE, Margolis T. Oral azithromycin for the treatment of meibomitis. JAMA Ophthalmol. 2014 Jan; 132(1):121-2. PMID: 24201556.
      View in: PubMed
    20. Maamari RN, Keenan JD, Fletcher DA, Margolis T. A mobile phone-based retinal camera for portable wide field imaging. Br J Ophthalmol. 2014 Apr; 98(4):438-41. PMID: 24344230.
      View in: PubMed
    21. Estopinal CB, Ausayakhun S, Ausayakhun S, Jirawison C, Joy Bhosai S, Margolis T, Keenan JD. Access to ophthalmologic care in Thailand: a regional analysis. Ophthalmic Epidemiol. 2013 Oct; 20(5):267-73. PMID: 24070100.
      View in: PubMed
    22. Bertke AS, Ma A, Margolis MS, Margolis T. Different mechanisms regulate productive herpes simplex virus 1 (HSV-1) and HSV-2 infections in adult trigeminal neurons. J Virol. 2013 Jun; 87(11):6512-6. PMID: 23514893; PMCID: PMC3648083.
    23. Heiden D, Margolis T, Lowinger A, Saranchuk P. Eye exam with indirect ophthalmoscopy for diagnosis of disseminated tuberculosis in patients with HIV/AIDS. Br J Ophthalmol. 2013 May; 97(5):668-9. PMID: 23418196.
      View in: PubMed
    24. Bertke AS, Apakupakul K, Ma A, Imai Y, Gussow AM, Wang K, Cohen JI, Bloom DC, Margolis T. LAT region factors mediating differential neuronal tropism of HSV-1 and HSV-2 do not act in trans. PLoS One. 2012; 7(12):e53281. PMID: 23300908; PMCID: PMC3534042.
    25. Fintelmann RE, Vastine DW, Bloomer MM, Margolis T. Thygeson superficial punctate keratitis and scarring. Cornea. 2012 Dec; 31(12):1446-8. PMID: 22495026.
      View in: PubMed
    26. Gonzales JA, Levison AL, Stewart JM, Acharya NR, Margolis T. Retinal necrosis following varicella-zoster vaccination. Arch Ophthalmol. 2012 Oct; 130(10):1355-6. PMID: 23044970.
      View in: PubMed
    27. Sy A, McLeod SD, Cohen EJ, Margolis T, Mannis MJ, Lietman TM, Acharya NR. Practice patterns and opinions in the management of recurrent or chronic herpes zoster ophthalmicus. Cornea. 2012 Jul; 31(7):786-90. PMID: 22269677; PMCID: PMC3729033.
    28. Smits SL, Manandhar A, van Loenen FB, van Leeuwen M, Baarsma GS, Dorrestijn N, Osterhaus AD, Margolis T, Verjans GM. High prevalence of anelloviruses in vitreous fluid of children with seasonal hyperacute panuveitis. J Infect Dis. 2012 Jun 15; 205(12):1877-84. PMID: 22492851.
      View in: PubMed
    29. Dalmon C, Porco TC, Lietman TM, Prajna NV, Prajna L, Das MR, Kumar JA, Mascarenhas J, Margolis T, Whitcher JP, Jeng BH, Keenan JD, Chan MF, McLeod SD, Acharya NR. The clinical differentiation of bacterial and fungal keratitis: a photographic survey. Invest Ophthalmol Vis Sci. 2012 Apr 02; 53(4):1787-91. PMID: 22395880; PMCID: PMC3342793.
    30. Chen J, Ausayakhun S, Tangmonkongvoragul C, Ausayakhun S, Jirawison C, Margolis T, Keenan JD. Incidence of cytomegalovirus retinitis in patients with human immunodeficiency virus following negative initial screening examination results. Arch Ophthalmol. 2012 Apr; 130(4):527-9. PMID: 22491928.
      View in: PubMed
    31. Ausayakhun S, Keenan JD, Ausayakhun S, Jirawison C, Khouri CM, Skalet AH, Heiden D, Holland GN, Margolis T. Clinical features of newly diagnosed cytomegalovirus retinitis in northern Thailand. Am J Ophthalmol. 2012 May; 153(5):923-931.e1. PMID: 22265148; PMCID: PMC3331920.
    32. Chen J, Ausayakhun S, Ausayakhun S, Jirawison C, Khouri CM, Porco TC, Heiden D, Keenan JD, Margolis T. Comparison of autophotomontage software programs in eyes with CMV retinitis. Invest Ophthalmol Vis Sci. 2011 Dec 09; 52(13):9339-44. PMID: 22064986; PMCID: PMC3250113.
    33. Ausayakhun S, Skalet AH, Jirawison C, Ausayakhun S, Keenan JD, Khouri C, Nguyen K, Kalyani PS, Heiden D, Holland GN, Margolis T. Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis. Am J Ophthalmol. 2011 Dec; 152(6):1053-1058.e1. PMID: 21861977.
      View in: PubMed
    34. Tun N, London N, Kyaw MK, Smithuis F, Ford N, Margolis T, Drew WL, Lewallen S, Heiden D. CMV retinitis screening and treatment in a resource-poor setting: three-year experience from a primary care HIV/AIDS programme in Myanmar. J Int AIDS Soc. 2011 Aug 15; 14:41. PMID: 21843351; PMCID: PMC3163508.
    35. Keenan JD, Mandel MR, Margolis T. Peripheral ulcerative keratitis associated with vasculitis manifesting asymmetrically as fuchs superficial marginal keratitis and terrien marginal degeneration. Cornea. 2011 Jul; 30(7):825-7. PMID: 21150425.
      View in: PubMed
    36. Bertke AS, Swanson SM, Chen J, Imai Y, Kinchington PR, Margolis T. A5-positive primary sensory neurons are nonpermissive for productive infection with herpes simplex virus 1 in vitro. J Virol. 2011 Jul; 85(13):6669-77. PMID: 21507969; PMCID: PMC3126511.
    37. Tang S, Bertke AS, Patel A, Margolis T, Krause PR. Herpes simplex virus 2 microRNA miR-H6 is a novel latency-associated transcript-associated microRNA, but reduction of its expression does not influence the establishment of viral latency or the recurrence phenotype. J Virol. 2011 May; 85(9):4501-9. PMID: 21325410; PMCID: PMC3126258.
    38. Khalifa YM, Bloomer MM, Margolis T. Secondary localized sectoral keratoconjunctival amyloidosis from ocular trauma. Cornea. 2010 Nov; 29(11):1328-9. PMID: 20697284.
      View in: PubMed
    39. Narkewicz MR, Rosenthal P, Schwarz KB, Drack A, Margolis T, Repka MX. Ophthalmologic complications in children with chronic hepatitis C treated with pegylated interferon. J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):183-6. PMID: 20512062; PMCID: PMC2910798.
    40. Khalifa YM, Jacoby RM, Margolis T. Exacerbation of zoster interstitial keratitis after zoster vaccination in an adult. Arch Ophthalmol. 2010 Aug; 128(8):1079-80. PMID: 20697015.
      View in: PubMed
    41. Jeng BH, Gritz DC, Kumar AB, Holsclaw DS, Porco TC, Smith SD, Whitcher JP, Margolis T, Wong IG. Epidemiology of ulcerative keratitis in Northern California. Arch Ophthalmol. 2010 Aug; 128(8):1022-8. PMID: 20697003.
      View in: PubMed
    42. Keenan JD, Fram NR, McLeod SD, Strauss EC, Margolis T. Perifosine-related rapidly progressive corneal ring infiltrate. Cornea. 2010 May; 29(5):583-5. PMID: 20335808.
      View in: PubMed
    43. Cohen JI, Fahle G, Kemp MA, Apakupakul K, Margolis T. Human herpesvirus 6-A, 6-B, and 7 in vitreous fluid samples. J Med Virol. 2010 May; 82(6):996-9. PMID: 20419813; PMCID: PMC2938775.
    44. Lin P, Loh AR, Margolis T, Acharya NR. Cigarette smoking as a risk factor for uveitis. Ophthalmology. 2010 Mar; 117(3):585-90. PMID: 20036011; PMCID: PMC2830339.
    45. Hu AY, Strauss EC, Holland GN, Chan MF, Yu F, Margolis T. Late varicella-zoster virus dendriform keratitis in patients with histories of herpes zoster ophthalmicus. Am J Ophthalmol. 2010 Feb; 149(2):214-220.e3. PMID: 19909942; PMCID: PMC4507370.
    46. Bertke AS, Patel A, Imai Y, Apakupakul K, Margolis T, Krause PR. Latency-associated transcript (LAT) exon 1 controls herpes simplex virus species-specific phenotypes: reactivation in the guinea pig genital model and neuron subtype-specific latent expression of LAT. J Virol. 2009 Oct; 83(19):10007-15. PMID: 19641003; PMCID: PMC2748022.
    47. Imai Y, Apakupakul K, Krause PR, Halford WP, Margolis T. Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia. J Virol. 2009 Aug; 83(16):7873-82. PMID: 19493993; PMCID: PMC2715745.
    48. Wang K, Mahalingam G, Imai Y, Pesnicak L, Margolis TP, Margolis T, Straus SE, Cohen JI. Cell type specific accumulation of the major latency-associated transcript (LAT) of herpes simplex virus type 2 in LAT transgenic mice. Virology. 2009 Mar 30; 386(1):79-87. PMID: 19200567; PMCID: PMC2692716.
    49. Nagpal A, Vora R, Margolis T, Acharya NR. Interstitial keratitis following varicella vaccination. Arch Ophthalmol. 2009 Feb; 127(2):222-3. PMID: 19204247.
      View in: PubMed
    50. Sansanayudh W, Cevallos V, Porco TC, Margolis T, Lietman TM, Acharya NR. Fusarium and Acanthamoeba keratitis: can a single centre detect outbreaks? Br J Ophthalmol. 2008 May; 92(5):720-1. PMID: 18441185; PMCID: PMC2586076.
    51. Leigh JF, Acharya N, Cevallos V, Margolis T. Does asymptomatic shedding of herpes simplex virus on the ocular surface lead to false-positive diagnostic PCR results? Br J Ophthalmol. 2008 Mar; 92(3):435-6. PMID: 18314406.
      View in: PubMed
    52. Heiden D, Ford N, Wilson D, Rodriguez WR, Margolis T, Janssens B, Bedelu M, Tun N, Goemaere E, Saranchuk P, Sabapathy K, Smithuis F, Luyirika E, Drew WL. Cytomegalovirus retinitis: the neglected disease of the AIDS pandemic. PLoS Med. 2007 Dec; 4(12):e334. PMID: 18052600; PMCID: PMC2100142.
    53. Margolis T, Elfman FL, Leib D, Pakpour N, Apakupakul K, Imai Y, Voytek C. Spontaneous reactivation of herpes simplex virus type 1 in latently infected murine sensory ganglia. J Virol. 2007 Oct; 81(20):11069-74. PMID: 17686862; PMCID: PMC2045564.
    54. Freidlin J, Acharya N, Lietman TM, Cevallos V, Whitcher JP, Margolis T. Spectrum of eye disease caused by methicillin-resistant Staphylococcus aureus. Am J Ophthalmol. 2007 Aug; 144(2):313-5. PMID: 17659970.
      View in: PubMed
    55. Acharya NR, Lietman TM, Margolis T. Parasites on the rise: a new epidemic of Acanthamoeba keratitis. Am J Ophthalmol. 2007 Aug; 144(2):292-3. PMID: 17659960.
      View in: PubMed
    56. Margolis T, Imai Y, Yang L, Vallas V, Krause PR. Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts. J Virol. 2007 Feb; 81(4):1872-8. PMID: 17151134; PMCID: PMC1797553.
    57. Prabriputaloong T, Margolis T, Lietman TM, Wong IG, Mather R, Gritz DC. Atopic disease and herpes simplex eye disease: a population-based case-control study. Am J Ophthalmol. 2006 Nov; 142(5):745-9. PMID: 17056358.
      View in: PubMed
    58. Stone DU, Char DH, Crawford JB, Margolis T, Van Gelder RN, Strauss EC. Metaplastic squamous epithelial downgrowth after clear corneal cataract surgery. Am J Ophthalmol. 2006 Oct; 142(4):695-7. PMID: 17011874.
      View in: PubMed
    59. Gussow AM, Giordani NV, Tran RK, Imai Y, Kwiatkowski DL, Rall GF, Margolis T, Bloom DC. Tissue-specific splicing of the herpes simplex virus type 1 latency-associated transcript (LAT) intron in LAT transgenic mice. J Virol. 2006 Oct; 80(19):9414-23. PMID: 16973547; PMCID: PMC1617271.
    60. Margolis T, Whitcher JP. Fusarium--A new culprit in the contact lens case. JAMA. 2006 Aug 23; 296(8):985-7. PMID: 16929565.
      View in: PubMed
    61. Nikulina K, Bodeker M, Warren J, Matthews P, Margolis T. A novel Krüppel related factor consisting of only a KRAB domain is expressed in the murine trigeminal ganglion. Biochem Biophys Res Commun. 2006 Sep 29; 348(3):839-49. PMID: 16904636.
      View in: PubMed
    62. Kim EC, Margolis T. Hypertensive iridocyclitis. Br J Ophthalmol. 2006 Jul; 90(7):812-3. PMID: 16782945; PMCID: PMC1857144.
    63. Seitzman GD, Strauss EC, Margolis T. "Steel wool keratopathy": a clinical sign of chronic inflammation. Cornea. 2006 Jul; 25(6):742-4. PMID: 17077672.
      View in: PubMed
    64. Halford WP, Weisend C, Grace J, Soboleski M, Carr DJ, Balliet JW, Imai Y, Margolis T, Gebhardt BM. ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virol J. 2006 Jun 09; 3:44. PMID: 16764725; PMCID: PMC1557838.
    65. Seitzman GD, Cevallos V, Margolis T. Rose bengal and lissamine green inhibit detection of herpes simplex virus by PCR. Am J Ophthalmol. 2006 Apr; 141(4):756-8. PMID: 16564821.
      View in: PubMed
    66. Acharya N, Lietman T, Cevallos V, Whitcher JP, Saidel M, Stone D, Duncan J, Margolis T. Correlation between clinical suspicion and polymerase chain reaction verification of infectious vitritis. Am J Ophthalmol. 2006 Mar; 141(3):584-5. PMID: 16490520.
      View in: PubMed
    67. Saidel MA, Berreen J, Margolis T. Cytomegalovirus retinitis after intravitreous triamcinolone in an immunocompetent patient. Am J Ophthalmol. 2005 Dec; 140(6):1141-3. PMID: 16376669.
      View in: PubMed
    68. Magone MT, Seitzman GD, Nehls S, Margolis T. Treatment of neurotrophic keratopathy with nasal dilator strips. Br J Ophthalmol. 2005 Nov; 89(11):1529-30. PMID: 16234466; PMCID: PMC1772934.
    69. McLeod SD, Mather R, Hwang DG, Margolis T. Uveitis-associated flap edema and lamellar interface fluid collection after LASIK. Am J Ophthalmol. 2005 Jun; 139(6):1137-9. PMID: 15953462.
      View in: PubMed
    70. Magone MT, Nasser RE, Cevallos AV, Margolis T. Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing. Am J Ophthalmol. 2005 Jun; 139(6):1135-6. PMID: 15953460.
      View in: PubMed
    71. Strauss EC, Aldave AJ, Spencer WH, Branco BC, Barsness DA, Calman AF, Margolis T. Management of prominent iris vascular tufts causing recurrent spontaneous hyphema. Cornea. 2005 Mar; 24(2):224-6. PMID: 15725893.
      View in: PubMed
    72. Vagefi MR, Hollander DA, Seitzman GD, Margolis T. Bilateral surgically induced necrotising scleritis with secondary superinfection. Br J Ophthalmol. 2005 Jan; 89(1):124-5. PMID: 15615764; PMCID: PMC1772468.
    73. Jeng BH, Margolis T, Chandra NS, McCalmont TH. Ocular findings as a presenting sign of hydroa vacciniforme. Br J Ophthalmol. 2004 Nov; 88(11):1478-9. PMID: 15489499; PMCID: PMC1772374.
    74. Branco BC, Gaudio PA, Margolis T. Epidemiology and molecular analysis of herpes simplex keratitis requiring primary penetrating keratoplasty. Br J Ophthalmol. 2004 Oct; 88(10):1285-8. PMID: 15377552; PMCID: PMC1772342.
    75. Margolis T, Lietman T, Strauss E. Infectious agents and ARMD: a connection? Am J Ophthalmol. 2004 Sep; 138(3):468-70. PMID: 15364231.
      View in: PubMed
    76. Jeng BH, Whitcher JP, Margolis T. Pseudogerontoxon. Clin Exp Ophthalmol. 2004 Aug; 32(4):433-4. PMID: 15281982.
      View in: PubMed
    77. Yoon MK, Warren JF, Holsclaw DS, Gritz DC, Margolis T. A novel arginine substitution mutation in 1A domain and a novel 27 bp insertion mutation in 2B domain of keratin 12 gene associated with Meesmann's corneal dystrophy. Br J Ophthalmol. 2004 Jun; 88(6):752-6. PMID: 15148206; PMCID: PMC1772161.
    78. Varaprasathan G, Miller K, Lietman T, Whitcher JP, Cevallos V, Okumoto M, Margolis T, Yinghui M, Cunningham ET. Trends in the etiology of infectious corneal ulcers at the F. I. Proctor Foundation. Cornea. 2004 May; 23(4):360-4. PMID: 15097130.
      View in: PubMed
    79. Jeng BH, Whitcher JP, Margolis T. Intracorneal graphite particles. Cornea. 2004 Apr; 23(3):319-20. PMID: 15084872.
      View in: PubMed
    80. Aldave AJ, Yellore VS, Thonar EJ, Udar N, Warren JF, Yoon MK, Cohen EJ, Rapuano CJ, Laibson PR, Margolis T, Small K. Novel mutations in the carbohydrate sulfotransferase gene (CHST6) in American patients with macular corneal dystrophy. Am J Ophthalmol. 2004 Mar; 137(3):465-73. PMID: 15013869.
      View in: PubMed
    81. Imai Y, Shum C, Martin DF, Kuppermann BD, Drew WL, Margolis T. Emergence of drug-resistant cytomegalovirus retinitis in the contralateral eyes of patients with AIDS treated with ganciclovir. J Infect Dis. 2004 Feb 15; 189(4):611-5. PMID: 14767813.
      View in: PubMed
    82. Warren JF, Abbott RL, Yoon MK, Crawford JB, Spencer WH, Margolis T. A new mutation (Leu569Arg) within exon 13 of the TGFBI (BIGH3) gene causes lattice corneal dystrophy type I. Am J Ophthalmol. 2003 Nov; 136(5):872-8. PMID: 14597039.
      View in: PubMed
    83. Warren JF, Aldave AJ, Srinivasan M, Thonar EJ, Kumar AB, Cevallos V, Whitcher JP, Margolis T. Novel mutations in the CHST6 gene associated with macular corneal dystrophy in southern India. Arch Ophthalmol. 2003 Nov; 121(11):1608-12. PMID: 14609920.
      View in: PubMed
    84. Pepose JS, Margolis T, LaRussa P, Pavan-Langston D. Ocular complications of smallpox vaccination. Am J Ophthalmol. 2003 Aug; 136(2):343-52. PMID: 12888060.
      View in: PubMed
    85. Strauss EC, Warren JF, Margolis T, Holsclaw DS. Diagnosis of conjunctival B-cell lymphoma by polymerase chain reaction heteroduplex analysis. Am J Ophthalmol. 2003 Jul; 136(1):207-9. PMID: 12834702.
      View in: PubMed
    86. Ellison AR, Yang L, Cevallos AV, Margolis T. Analysis of the herpes simplex virus type 1 UL6 gene in patients with stromal keratitis. Virology. 2003 May 25; 310(1):24-8. PMID: 12788627.
      View in: PubMed
    87. Kuo IC, Imai Y, Shum C, Martin DF, Kuppermann BD, Margolis T. Genotypic analysis of cytomegalovirus retinitis poorly responsive to intravenous ganciclovir but responsive to the ganciclovir implant. Am J Ophthalmol. 2003 Jan; 135(1):20-5. PMID: 12504692.
      View in: PubMed
    88. Sherman MD, Feldman KA, Farahmand SM, Margolis T. Treatment of conjunctival squamous cell carcinoma with topical cidofovir. Am J Ophthalmol. 2002 Sep; 134(3):432-3. PMID: 12208255.
      View in: PubMed
    89. Alrawi AM, Chern KC, Cevallos V, Lietman T, Whitcher JP, Margolis T, Cunningham ET. Biotypes and serotypes of Haemophilus influenzae ocular isolates. Br J Ophthalmol. 2002 Mar; 86(3):276-7. PMID: 11864881; PMCID: PMC1771031.
    90. Feldman LT, Ellison AR, Voytek CC, Yang L, Krause P, Margolis T. Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):978-83. PMID: 11773630; PMCID: PMC117416.
    91. Naseri A, Margolis T. Varicella zoster virus immune recovery stromal keratitis in a patient with AIDS. Br J Ophthalmol. 2001 Nov; 85(11):1390-1. PMID: 11702739; PMCID: PMC1723762.
    92. Grigg ME, Ganatra J, Boothroyd JC, Margolis T. Unusual abundance of atypical strains associated with human ocular toxoplasmosis. J Infect Dis. 2001 Sep 01; 184(5):633-9. PMID: 11474426.
      View in: PubMed
    93. Summers BC, Margolis T, Leib DA. Herpes simplex virus type 1 corneal infection results in periocular disease by zosteriform spread. J Virol. 2001 Jun; 75(11):5069-75. PMID: 11333887; PMCID: PMC114911.
    94. Kuo IC, Margolis T, Cevallos V, Hwang DG. Aspergillus fumigatus keratitis after laser in situ keratomileusis. Cornea. 2001 Apr; 20(3):342-4. PMID: 11322429.
      View in: PubMed
    95. Liu W, Shum C, Martin DF, Kuppermann BD, Hall AJ, Margolis T. Prevalence of antiviral drug resistance in untreated patients with cytomegalovirus retinitis. J Infect Dis. 2000 Oct; 182(4):1234-8. PMID: 10979924.
      View in: PubMed
    96. Kuo IC, Rechdouni A, Rao NA, Johnston RH, Margolis T, Cunningham ET. Subretinal fibrosis in patients with Vogt-Koyanagi-Harada disease. Ophthalmology. 2000 Sep; 107(9):1721-8. PMID: 10964836.
      View in: PubMed
    97. Berthomme H, Lokensgard J, Yang L, Margolis T, Feldman LT. Evidence for a bidirectional element located downstream from the herpes simplex virus type 1 latency-associated promoter that increases its activity during latency. J Virol. 2000 Apr; 74(8):3613-22. PMID: 10729137; PMCID: PMC111871.
    98. Margolis T. Discontinuation of anticytomegalovirus therapy in patients with HIV infection and cytomegalovirus retinitis. Surv Ophthalmol. 2000 Mar-Apr; 44(5):455. PMID: 10809654.
      View in: PubMed
    99. Ellison AR, Yang L, Voytek C, Margolis T. Establishment of latent herpes simplex virus type 1 infection in resistant, sensitive, and immunodeficient mouse strains. Virology. 2000 Mar 01; 268(1):17-28. PMID: 10683323.
      View in: PubMed
    100. Ganatra JB, Chandler D, Santos C, Kuppermann B, Margolis T. Viral causes of the acute retinal necrosis syndrome. Am J Ophthalmol. 2000 Feb; 129(2):166-72. PMID: 10682968.
      View in: PubMed
    101. Yang L, Voytek CC, Margolis T. Immunohistochemical analysis of primary sensory neurons latently infected with herpes simplex virus type 1. J Virol. 2000 Jan; 74(1):209-17. PMID: 10590108; PMCID: PMC111530.
    102. Gaynor BD, Margolis T, Cunningham ET. Advances in diagnosis and management of herpetic uveitis. Int Ophthalmol Clin. 2000; 40(2):85-109. PMID: 10791259.
      View in: PubMed
    103. Jacobson MA, Stanley H, Holtzer C, Margolis T, Cunningham ET. Natural history and outcome of new AIDS-related cytomegalovirus retinitis diagnosed in the era of highly active antiretroviral therapy. Clin Infect Dis. 2000 Jan; 30(1):231-3. PMID: 10619774.
      View in: PubMed
    104. Knox CM, Cevallos V, Margolis T, Dean D. Identification of bacterial pathogens in patients with endophthalmitis by 16S ribosomal DNA typing. Am J Ophthalmol. 1999 Oct; 128(4):511-2. PMID: 10577597.
      View in: PubMed
    105. Zegans ME, Srinivasan M, McHugh T, Whitcher JP, Margolis T, Lietman T, Jennette JC, Cunningham ET. Mooren ulcer in South India: serology and clinical risk factors. Am J Ophthalmol. 1999 Aug; 128(2):205-10. PMID: 10458177.
      View in: PubMed
    106. Holland GN, Van Horn SD, Margolis T. Cataract surgery with ciliary sulcus fixation of intraocular lenses in patients with uveitis. Am J Ophthalmol. 1999 Jul; 128(1):21-30. PMID: 10482090.
      View in: PubMed
    107. Chern KC, Chandler DB, Martin DF, Kuppermann BD, Wolitz RA, Margolis T. Glycoprotein B subtyping of cytomegalovirus (CMV) in the vitreous of patients with AIDS and CMV retinitis. J Infect Dis. 1998 Oct; 178(4):1149-53. PMID: 9806048.
      View in: PubMed
    108. Chern KC, Conrad D, Holland GN, Holsclaw DS, Schwartz LK, Margolis T. Chronic varicella-zoster virus epithelial keratitis in patients with acquired immunodeficiency syndrome. Arch Ophthalmol. 1998 Aug; 116(8):1011-7. PMID: 9715680.
      View in: PubMed
    109. Cunningham ET, Margolis T. Ocular manifestations of HIV infection. N Engl J Med. 1998 Jul 23; 339(4):236-44. PMID: 9673303.
      View in: PubMed
    110. Hodge WG, Seiff SR, Margolis T. Ocular opportunistic infection incidences among patients who are HIV positive compared to patients who are HIV negative. Ophthalmology. 1998 May; 105(5):895-900. PMID: 9593394.
      View in: PubMed
    111. Liu W, Kuppermann BD, Martin DF, Wolitz RA, Margolis T. Mutations in the cytomegalovirus UL97 gene associated with ganciclovir-resistant retinitis. J Infect Dis. 1998 May; 177(5):1176-81. PMID: 9593000.
      View in: PubMed
    112. Zegans ME, Walton RC, Holland GN, O'Donnell JJ, Jacobson MA, Margolis T. Transient vitreous inflammatory reactions associated with combination antiretroviral therapy in patients with AIDS and cytomegalovirus retinitis. Am J Ophthalmol. 1998 Mar; 125(3):292-300. PMID: 9512145.
      View in: PubMed
    113. Margolis T, Milner MS, Shama A, Hodge W, Seiff S. Herpes zoster ophthalmicus in patients with human immunodeficiency virus infection. Am J Ophthalmol. 1998 Mar; 125(3):285-91. PMID: 9512144.
      View in: PubMed
    114. Chern KC, Margolis T. Varicella zoster virus ocular disease. Int Ophthalmol Clin. 1998; 38(4):149-60. PMID: 10081731.
      View in: PubMed
    115. Knox CM, Chandler D, Short GA, Margolis T. Polymerase chain reaction-based assays of vitreous samples for the diagnosis of viral retinitis. Use in diagnostic dilemmas. Ophthalmology. 1998 Jan; 105(1):37-44; discussion 44-5. PMID: 9442777.
      View in: PubMed
    116. Silverstein BE, Cunningham ET, Margolis T, Cevallos V, Wong IG. Microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus infection. Am J Ophthalmol. 1997 Sep; 124(3):395-6. PMID: 9439367.
      View in: PubMed
    117. Gritz DC, Holsclaw DS, Neger RE, Whitcher JP, Margolis T. Ocular and sinus microsporidial infection cured with systemic albendazole. Am J Ophthalmol. 1997 Aug; 124(2):241-3. PMID: 9262551.
      View in: PubMed
    118. Gritz DC, Scott TJ, Sedó SF, Cevallos AV, Margolis T, Whitcher JP. Ocular flora of patients with AIDS compared with those of HIV-negative patients. Cornea. 1997 Jul; 16(4):400-5. PMID: 9220236.
      View in: PubMed
    119. Cunningham ET, Stalder AK, Sanna PP, Liu SS, Bloom FE, Howes EL, Campbell IL, Margolis T. Distribution of tumor necrosis factor receptor messenger RNA in normal and herpes simplex virus infected trigeminal ganglia in the mouse. Brain Res. 1997 May 30; 758(1-2):99-106. PMID: 9203538.
      View in: PubMed
    120. Knox CM, Whitcher JP, Cevellos V, Margolis T, Irvine AR. Nocardia scleritis. Am J Ophthalmol. 1997 May; 123(5):713-4. PMID: 9152089.
      View in: PubMed
    121. Silverstein BE, Conrad D, Margolis T, Wong IG. Cytomegalovirus-associated acute retinal necrosis syndrome. Am J Ophthalmol. 1997 Feb; 123(2):257-8. PMID: 9186135.
      View in: PubMed
    122. Short GA, Margolis T, Kuppermann BD, Irvine AR, Martin DF, Chandler D. A polymerase chain reaction-based assay for diagnosing varicella-zoster virus retinitis in patients with acquired immunodeficiency syndrome. Am J Ophthalmol. 1997 Feb; 123(2):157-64. PMID: 9186120.
      View in: PubMed
    123. Silverstein BE, Chandler D, Neger R, Margolis T. Disciform keratitis: a case of herpes zoster sine herpete. Am J Ophthalmol. 1997 Feb; 123(2):254-5. PMID: 9186133.
      View in: PubMed
    124. Hodge WG, Margolis T. Herpes simplex virus keratitis among patients who are positive or negative for human immunodeficiency virus: an epidemiologic study. Ophthalmology. 1997 Jan; 104(1):120-4. PMID: 9022115.
      View in: PubMed
    125. Cunningham ET, Stalder A, Sanna PP, Liu SS, Bloom FE, Howes EL, Campbell IL, Margolis T. Localization of tumor necrosis factor receptor messenger RNA in normal and herpes simplex virus-infected mouse eyes. Invest Ophthalmol Vis Sci. 1997 Jan; 38(1):9-15. PMID: 9008625.
      View in: PubMed
    126. Cunningham ET, Short GA, Irvine AR, Duker JS, Margolis T. Acquired immunodeficiency syndrome--associated herpes simplex virus retinitis. Clinical description and use of a polymerase chain reaction--based assay as a diagnostic tool. Arch Ophthalmol. 1996 Jul; 114(7):834-40. PMID: 8660167.
      View in: PubMed
    127. Holsclaw DS, Whitcher JP, Wong IG, Margolis T. Supratarsal injection of corticosteroid in the treatment of refractory vernal keratoconjunctivitis. Am J Ophthalmol. 1996 Mar; 121(3):243-9. PMID: 8597266.
      View in: PubMed
    128. Wilkins J, Whitcher JP, Margolis T. Penicillin-resistant Streptococcus pneumoniae keratitis. Cornea. 1996 Jan; 15(1):99-100. PMID: 8907389.
      View in: PubMed
    129. McCann JD, Margolis T, Wong MG, Kuppermann BD, Luckie AP, Schwartz DM, Irvine AR, Ai E. A sensitive and specific polymerase chain reaction-based assay for the diagnosis of cytomegalovirus retinitis. Am J Ophthalmol. 1995 Aug; 120(2):219-26. PMID: 7639306.
      View in: PubMed
    130. Hodge W, Wohl T, Whitcher JP, Margolis T. Corneal subepithelial infiltrate recurrence sine adenovirus. Cornea. 1995 May; 14(3):324-5. PMID: 7600819.
      View in: PubMed
    131. Dobson AT, Margolis T, Gomes WA, Feldman LT. In vivo deletion analysis of the herpes simplex virus type 1 latency-associated transcript promoter. J Virol. 1995 Apr; 69(4):2264-70. PMID: 7884873; PMCID: PMC188896.
    132. Farrell MJ, Margolis T, Gomes WA, Feldman LT. Effect of the transcription start region of the herpes simplex virus type 1 latency-associated transcript promoter on expression of productively infected neurons in vivo. J Virol. 1994 Sep; 68(9):5337-43. PMID: 8057417; PMCID: PMC236933.
    133. Engstrom RE, Holland GN, Margolis T, Muccioli C, Lindley JI, Belfort R, Holland SP, Johnston WH, Wolitz RA, Kreiger AE. The progressive outer retinal necrosis syndrome. A variant of necrotizing herpetic retinopathy in patients with AIDS. Ophthalmology. 1994 Sep; 101(9):1488-502. PMID: 8090452.
      View in: PubMed
    134. Joshi N, Constable PH, Margolis T, Hoyt CS, Leonard TJ. Bilateral angle closure glaucoma and accelerated cataract formation in a patient with AIDS. Br J Ophthalmol. 1994 Aug; 78(8):656-7. PMID: 7918297; PMCID: PMC504896.
    135. Wilkins JH, Joshi N, Margolis T, Cevallos V, Dawson CR. Microsporidial keratoconjunctivitis treated successfully with a short course of fumagillin. Eye (Lond). 1994; 8 ( Pt 6):703-4. PMID: 7867837.
      View in: PubMed
    136. Margolis T, Bloom DC, Dobson AT, Feldman LT, Stevens JG. Decreased reporter gene expression during latent infection with HSV LAT promoter constructs. Virology. 1993 Dec; 197(2):585-92. PMID: 8249281.
      View in: PubMed
    137. Farrell MJ, Hill JM, Margolis T, Stevens JG, Wagner EK, Feldman LT. The herpes simplex virus type 1 reactivation function lies outside the latency-associated transcript open reading frame ORF-2. J Virol. 1993 Jun; 67(6):3653-5. PMID: 8388517; PMCID: PMC237719.
    138. Sedarati F, Margolis T, Stevens JG. Latent infection can be established with drastically restricted transcription and replication of the HSV-1 genome. Virology. 1993 Feb; 192(2):687-91. PMID: 8380670.
      View in: PubMed
    139. Seiff SR, Margolis T. Readers comment on "Herpes zoster ophthalmicus". Surv Ophthalmol. 1992 Sep-Oct; 37(2):150; author reply 152-3. PMID: 1455299.
      View in: PubMed
    140. Margolis T, Sedarati F, Dobson AT, Feldman LT, Stevens JG. Pathways of viral gene expression during acute neuronal infection with HSV-1. Virology. 1992 Jul; 189(1):150-60. PMID: 1604806.
      View in: PubMed
    141. Margolis T, Dawson CR, LaVail JH. Herpes simplex viral infection of the mouse trigeminal ganglion. Immunohistochemical analysis of cell populations. Invest Ophthalmol Vis Sci. 1992 Feb; 33(2):259-67. PMID: 1371269.
      View in: PubMed
    142. Gardner BP, Margolis T, Mondino BJ. Conjunctival lymphocytic nodule associated with the Epstein-Barr virus. Am J Ophthalmol. 1991 Nov 15; 112(5):567-71. PMID: 1659201.
      View in: PubMed
    143. Margolis T, Lowder CY, Holland GN, Spaide RF, Logan AG, Weissman SS, Irvine AR, Josephberg R, Meisler DM, O'Donnell JJ. Varicella-zoster virus retinitis in patients with the acquired immunodeficiency syndrome. Am J Ophthalmol. 1991 Aug 15; 112(2):119-31. PMID: 1651054.
      View in: PubMed
    144. Margolis T, Ostler HB. Treatment of ocular disease in eczema herpeticum. Am J Ophthalmol. 1990 Sep 15; 110(3):274-9. PMID: 2118723.
      View in: PubMed
    145. Dobson AT, Margolis T, Sedarati F, Stevens JG, Feldman LT. A latent, nonpathogenic HSV-1-derived vector stably expresses beta-galactosidase in mouse neurons. Neuron. 1990 Sep; 5(3):353-60. PMID: 2169271.
      View in: PubMed
    146. LaVail JH, Zhan J, Margolis T. HSV (type 1) infection of the trigeminal complex. Brain Res. 1990 Apr 30; 514(2):181-8. PMID: 2357535.
      View in: PubMed
    147. Margolis T, LaVail JH, Setzer PY, Dawson CR. Selective spread of herpes simplex virus in the central nervous system after ocular inoculation. J Virol. 1989 Nov; 63(11):4756-61. PMID: 2552151; PMCID: PMC251112.
    148. Seiff SR, Margolis T, Graham SH, O'Donnell JJ. Use of intravenous acyclovir for treatment of herpes zoster ophthalmicus in patients at risk for AIDS. Ann Ophthalmol. 1988 Dec; 20(12):480-2. PMID: 3265292.
      View in: PubMed
    149. Margolis T, Irvine AR, Hoyt WF, Hyman R. Acute retinal necrosis syndrome presenting with papillitis and arcuate neuroretinitis. Ophthalmology. 1988 Jul; 95(7):937-40. PMID: 3174044.
      View in: PubMed
    150. Margolis T, Togni B, LaVail J, Dawson CR. Identifying HSV infected neurons after ocular inoculation. Curr Eye Res. 1987 Jan; 6(1):119-26. PMID: 3030634.
      View in: PubMed
    151. Margolis T, LaVail JH. Further evidence in support of the selective uptake and anterograde transport of [125I]wheat germ agglutinin by chick retinal ganglion cells. Brain Res. 1984 Dec 17; 324(1):21-7. PMID: 6083824.
      View in: PubMed
    152. Margolis T, LaVail JH. Rate of anterograde axonal transport of [125I]wheat germ agglutinin from retina to optic tectum in the chick. Brain Res. 1981 Dec 14; 229(1):218-23. PMID: 6171327.
      View in: PubMed
    153. Margolis T, Marchand CM, Kistler HB, LaVail LH. Uptake and anterograde axonal transport of wheat germ agglutinin from retina to optic tectum in the chick. J Cell Biol. 1981 Apr; 89(1):152-6. PMID: 6164680; PMCID: PMC2111779.
    Todd's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _
    Back to TOP