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Vasantha Jotwani, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Northwestern UniversityBS2003Biomedical Engineering
    Northwestern UniversityM.D.2008Feinberg School of Medicine
    University of California San FranciscoInternship2009Internal Medicine
    University of California San FranciscoResidency2011Internal Medicine
    University of California San FranciscoChief Residency2012Internal Medicine
    University of California San FranciscoClinical Fellowship2014Division of Nephrology

    Collapse Research 
    Collapse Research Activities and Funding
    Biomarkers of Drug-induced Kidney Injury in HIV
    NIH/NIDDK K23DK109868Sep 15, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Novel biomarkers of kidney injury in HIV-infected men
    NIH/NIDDK F32DK103451Jul 3, 2014 - Jul 2, 2016
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Ascher SB, Scherzer R, Estrella MM, Shigenaga J, Spaulding KA, Glidden DV, Mehrotra ML, Defechereux P, Gandhi M, Grant RM, Shlipak MG, Jotwani V. HIV pre-exposure prophylaxis with tenofovir disoproxil fumarate/emtricitabine and changes in kidney function and tubular health. AIDS. 2019 Dec 02. PMID: 31794523.
      View in: PubMed
    2. Garimella PS, Lee AK, Ambrosius WT, Bhatt U, Cheung AK, Chonchol M, Craven T, Hawfield AT, Jotwani V, Killeen A, Punzi H, Sarnak MJ, Wall BM, Ix JH, Shlipak MG. Markers of kidney tubule function and risk of cardiovascular disease events and mortality in the SPRINT trial. Eur Heart J. 2019 Nov 01; 40(42):3486-3493. PMID: 31257404.
      View in: PubMed
    3. Ascher SB, Scherzer R, Nishtala A, Jotwani V, Grunfeld C, Parikh CR, Ng D, Wang R, Palella FJ, Shlipak MG, Estrella MM. Association of Statin Use With Kidney Damage and Function Among HIV-Infected Men. J Acquir Immune Defic Syndr. 2019 Oct 01; 82(2):202-210. PMID: 31356467.
      View in: PubMed
    4. Ascher SB, Scherzer R, Estrella MM, Shlipak MG, Ng DK, Palella FJ, Witt MD, Ho K, Bennett MR, Parikh CR, Ix JH, Jotwani V. Associations of Urine Biomarkers with Kidney Function Decline in HIV-Infected and Uninfected Men. Am J Nephrol. 2019; 50(5):401-410. PMID: 31553981.
      View in: PubMed
    5. Lee AK, Katz R, Jotwani V, Garimella PS, Ambrosius WT, Cheung AK, Gren LH, Neyra JA, Punzi H, Raphael KL, Shlipak MG, Ix JH. Distinct Dimensions of Kidney Health and Risk of Cardiovascular Disease, Heart Failure, and Mortality. Hypertension. 2019 10; 74(4):872-879. PMID: 31378102.
      View in: PubMed
    6. Bullen AL, Katz R, Lee AK, Anderson CAM, Cheung AK, Garimella PS, Jotwani V, Haley WE, Ishani A, Lash JP, Neyra JA, Punzi H, Rastogi A, Riessen E, Malhotra R, Parikh CR, Rocco MV, Wall BM, Bhatt UY, Shlipak MG, Ix JH, Estrella MM. The SPRINT trial suggests that markers of tubule cell function in the urine associate with risk of subsequent acute kidney injury while injury markers elevate after the injury. Kidney Int. 2019 Aug; 96(2):470-479. PMID: 31262489.
      View in: PubMed
    7. Jotwani VK, Lee AK, Estrella MM, Katz R, Garimella PS, Malhotra R, Rifkin DE, Ambrosius W, Freedman BI, Cheung AK, Raphael KL, Drawz P, Neyra JA, Oparil S, Punzi H, Shlipak MG, Ix JH. Urinary Biomarkers of Tubular Damage Are Associated with Mortality but Not Cardiovascular Risk among Systolic Blood Pressure Intervention Trial Participants with Chronic Kidney Disease. Am J Nephrol. 2019; 49(5):346-355. PMID: 30939472.
      View in: PubMed
    8. Zhang WR, Scherzer R, Estrella MM, Ascher SB, Muiru A, Jotwani V, Grunfeld C, Parikh CR, Gustafson D, Kassaye S, Sharma A, Cohen M, Tien PC, Ng DK, Palella FJ, Witt MD, Ho K, Shlipak MG. Tenofovir disoproxil fumarate initiation and changes in urinary biomarker concentrations among HIV-infected men and women. AIDS. 2019 03 15; 33(4):723-733. PMID: 30830887.
      View in: PubMed
    9. Alexandra K Lee, Ronit Katz, Walter T Ambrosius, Alfred K Cheung, Pranav Garimella, Lisa H Gren, Vasantha Jotwani, Javier A Neyra, Henry Punzi, Kalani Raphael, Joachim H Ix, Michael Shlipak. Abstract MP09: Indices of Kidney Tubular Health Improve Cardiovascular Disease Risk Prediction in Adults With Hypertension and Chronic Kidney Disease in SPRINT. Circulation. 2019 Mar 5; 139(Suppl_1).
      View in: Publisher Site
    10. Muiru AN, Shlipak MG, Scherzer R, Zhang WR, Ascher SB, Jotwani V, Grunfeld C, Parikh CR, Ng D, Palella FJ, Ho K, Kassaye S, Sharma A, Cohen M, Wang R, Qi Q, Estrella MM. Kidney disease risk factors associate with urine biomarkers concentrations in HIV-positive persons; a cross-sectional study. BMC Nephrol. 2019 01 03; 20(1):4. PMID: 30606136.
      View in: PubMed
    11. William R. Zhang, Rebecca Scherzer, Michelle M. Estrella, Simon B. Ascher, Anthony Muiru, Vasantha Jotwani, Carl Grunfeld, Chirag R. Parikh, Deborah Gustafson, Seble Kassaye, Anjali Sharma, Mardge Cohen, Phyllis C. Tien, Derek K. Ng, Frank J. Palella, Mallory D. Witt, Ken Ho, Michael G. Shlipak. Tenofovir disoproxil fumarate initiation and changes in urinary biomarker concentrations among HIV-infected men and women. AIDS. 2018 Dec 1; Publish Ahead of Print(&NA;):&na;.
      View in: Publisher Site
    12. Ascher SB, Scherzer R, Estrella MM, Zhang WR, Muiru AN, Jotwani V, Grunfeld C, Parikh CR, Gustafson D, Young M, Sharma A, Cohen MH, Ng DK, Palella FJ, Witt MD, Ho K, Shlipak MG. Association of Urinary Biomarkers of Kidney Injury with Estimated GFR Decline in HIV-Infected Individuals following Tenofovir Disoproxil Fumarate Initiation. Clin J Am Soc Nephrol. 2018 09 07; 13(9):1321-1329. PMID: 30154221.
      View in: PubMed
    13. Jotwani V, Scherzer R, Glidden DV, Mehrotra M, Defechereux P, Liu A, Gandhi M, Bennett M, Coca SG, Parikh CR, Grant RM, Shlipak MG. Pre-exposure Prophylaxis With Tenofovir Disoproxil Fumarate/Emtricitabine and Kidney Tubular Dysfunction in HIV-Uninfected Individuals. J Acquir Immune Defic Syndr. 2018 06 01; 78(2):169-174. PMID: 29767638.
      View in: PubMed
    14. Jotwani V, Katz R, Ix JH, Gutiérrez OM, Bennett M, Parikh CR, Cummings SR, Sarnak MJ, Shlipak MG. Urinary Biomarkers of Kidney Tubular Damage and Risk of Cardiovascular Disease and Mortality in Elders. Am J Kidney Dis. 2018 08; 72(2):205-213. PMID: 29602632.
      View in: PubMed
    15. Jotwani V, Atta MG, Estrella MM. Kidney Disease in HIV: Moving beyond HIV-Associated Nephropathy. J Am Soc Nephrol. 2017 Nov; 28(11):3142-3154. PMID: 28784698.
      View in: PubMed
    16. Ix JH, Jotwani V, Shlipak MG. In Reply to 'Urinary Excretion of a1-Microglobulin Does Not Predict Graft Loss in Stable Kidney Transplant Recipients'. Am J Kidney Dis. 2017 07; 70(1):151-152. PMID: 28501241.
      View in: PubMed
    17. Park M, Katz R, Shlipak MG, Weiner D, Tracy R, Jotwani V, Hughes-Austin J, Gabbai F, Hsu CY, Pfeffer M, Bansal N, Bostom A, Gutierrez O, Sarnak M, Levey A, Ix JH. Urinary Markers of Fibrosis and Risk of Cardiovascular Events and Death in Kidney Transplant Recipients: The FAVORIT Trial. Am J Transplant. 2017 Oct; 17(10):2640-2649. PMID: 28371433.
      View in: PubMed
    18. Chen R, Scherzer R, Hsue PY, Jotwani V, Estrella MM, Horberg MA, Grunfeld C, Shlipak MG. Association of Tenofovir Use With Risk of Incident Heart Failure in HIV-Infected Patients. J Am Heart Assoc. 2017 Apr 24; 6(4). PMID: 28438737.
      View in: PubMed
    19. Baxi SM, Scherzer R, Jotwani V, Estrella MM, Abraham AG, Parikh CR, Bennett MR, Cohen MH, Nowicki MJ, Gustafson DR, Sharma A, Young MA, Shlipak MG. Changes in Urinary Biomarkers Over 10 Years Is Associated With Viral Suppression in a Prospective Cohort of Women Living With HIV. J Acquir Immune Defic Syndr. 2017 Apr 15; 74(5):e138-e145. PMID: 27759575.
      View in: PubMed
    20. Jotwani V, Scherzer R, Estrella MM, Jacobson LP, Witt MD, Palella F, Ho K, Bennett M, Parikh CR, Ix JH, Shlipak M. Association of HIV infection with biomarkers of kidney injury and fibrosis in the Multicenter AIDS Cohort Study. Antivir Ther. 2017; 22(5):421-429. PMID: 28054933.
      View in: PubMed
    21. Ix JH, Katz R, Bansal N, Foster M, Weiner DE, Tracy R, Jotwani V, Hughes-Austin J, McKay D, Gabbai F, Hsu CY, Bostom A, Levey AS, Shlipak MG. Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial. Am J Kidney Dis. 2017 Mar; 69(3):410-419. PMID: 28024930.
      View in: PubMed
    22. Jotwani V, Scherzer R, Estrella MM, Jacobson LP, Witt MD, Palella F, Macatangay B, Bennett M, Parikh CR, Ix JH, Shlipak M. Brief Report: Cumulative Tenofovir Disoproxil Fumarate Exposure is Associated With Biomarkers of Tubular Injury and Fibrosis in HIV-Infected Men. J Acquir Immune Defic Syndr. 2016 10 01; 73(2):177-81. PMID: 27088295.
      View in: PubMed
    23. Jotwani V, Scherzer R, Estrella MM, Jacobson LP, Witt MD, Palella FJ, Macatangay B, Bennett M, Parikh CR, Ix JH, Shlipak MG. HIV Infection, Tenofovir, and Urine a1-Microglobulin: A Cross-sectional Analysis in the Multicenter AIDS Cohort Study. Am J Kidney Dis. 2016 Oct; 68(4):571-581. PMID: 27287300.
      View in: PubMed
    24. Scherzer R, Lin H, Abraham A, Thiessen-Philbrook H, Parikh CR, Bennett M, Cohen MH, Nowicki M, Gustafson DR, Sharma A, Young M, Tien P, Jotwani V, Shlipak MG. Use of urine biomarker-derived clusters to predict the risk of chronic kidney disease and all-cause mortality in HIV-infected women. Nephrol Dial Transplant. 2016 09; 31(9):1478-85. PMID: 26754833.
      View in: PubMed
    25. Jotwani V, Shlipak MG, Scherzer R, Parekh RS, Kao WH, Bennett M, Cohen MH, Nowicki M, Sharma A, Young M, Tien PC, Parikh CR, Estrella MM. APOL1 Genotype and Glomerular and Tubular Kidney Injury in Women With HIV. Am J Kidney Dis. 2015 Jun; 65(6):889-98. PMID: 25921719.
      View in: PubMed
    26. Jotwani V, Scherzer R, Abraham A, Estrella MM, Bennett M, Cohen MH, Nowicki M, Sharma A, Young M, Tien PC, Ix JH, Sarnak MJ, Parikh CR, Shlipak MG. Association of urine a1-microglobulin with kidney function decline and mortality in HIV-infected women. Clin J Am Soc Nephrol. 2015 Jan 07; 10(1):63-73. PMID: 25370597.
      View in: PubMed
    27. Jotwani V, Scherzer R, Abraham A, Estrella MM, Bennett M, Devarajan P, Anastos K, Cohen MH, Nowicki M, Sharma A, Young M, Tien PC, Grunfeld C, Parikh CR, Shlipak MG. Does HIV infection promote early kidney injury in women? Antivir Ther. 2014; 19(1):79-87. PMID: 23970313.
      View in: PubMed
    28. Jotwani V, Li Y, Grunfeld C, Choi AI, Shlipak MG. Risk factors for ESRD in HIV-infected individuals: traditional and HIV-related factors. Am J Kidney Dis. 2012 May; 59(5):628-35. PMID: 22206742.
      View in: PubMed
    29. Jotwani V, Scherzer R, Choi A, Szczech L, Polak JF, Kronmal RA, Grunfeld C, Shlipak M. Reduced kidney function and preclinical atherosclerosis in HIV-infected individuals: the study of fat redistribution and metabolic change in HIV infection (FRAM). Am J Nephrol. 2011; 33(5):453-60. PMID: 21508633.
      View in: PubMed
    30. Kolavennu V, Zeng L, Peng H, Wang Y, Danesh FR. Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control. Diabetes. 2008 Mar; 57(3):714-23. PMID: 18083785.
      View in: PubMed