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Jennifer Lai, MD, MBA

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Phone415-476-6422
ORCID ORCID Icon0000-0003-2092-6380 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityB.S.2000
    Tufts University School of MedicineM.D./M.B.A.2005School of Medicine
    Columbia University Medical CenterInternship/Residency2008Department of Medicine
    UCSFAdvanced Training in Clinical Research2010
    UCSFFellowship in Gastroenterology2011
    UCSFFellowship in Advanced/Transplant Hepatology2012
    Collapse Awards and Honors
    UCSF2019Floyd Rector Internal Medicine Research Mentoring Award
    American Society of Transplantation2017Fellow
    American Society of Transplantation2016Clinical Science Career Development Award
    American Society of Transplantation2016  - 2017AST/Novartis Faculty Development Award (grant)
    American Geriatrics Society2015New Investigator Award
    International Liver Transplantation Society2015Young Investigator Award
    American Federation for Aging Research2014  - 2019Paul B. Beeson Scholar in Aging Research (grant)
    UCSF Pepper Center2014  - 2015Associate Scholar Genius Award (grant)
    Association of Specialty Professors2013  - 2015T. Franklin Williams Scholar (grant)
    American College of Gastroenterology2012  - 2015Junior Faculty Career Development Award (grant)
    American College of Gastrenterology2011  - 2012Clinical Research Award (grant)
    American Association for the Study of Liver Diseases2011  - 2012Transplant Hepatology Fellowship (grant)
    International Liver Transplantation Society2011Vanguard Award
    Northern California Kaiser Permanente2009  - 2010Sylvia Allison Kaplan Clinical Research Award (grant)
    Tufts University School of Medicine2005Alpha Omega Alpha

    Collapse Overview 
    Collapse Overview
    Dr. Lai is a general and transplant hepatologist who specializes in caring for patients with chronic viral hepatitis, autoimmune disorders, and cirrhosis, particularly those awaiting liver transplantation.

    Her academic mission is to improve the lives of patients with end-stage liver disease through the application of core principles of geriatrics into the care of patients with cirrhosis. Examples of these principles include assessing and reversing physical frailty, reducing polypharmacy, and integrating palliative care into liver transplantation. She is principal investigator of the NIH-funded Functional Assessment in Liver Transplantation (FrAILT) Study, which is actively enrolling patients with end-stage liver disease awaiting liver transplantation for assessments of physical frailty both before and after liver transplantation.

    After earning her undergraduate degree from Stanford University and combined MD/MBA degrees from Tufts University, she completed residency at the New York Presbyterian Hospital-Columbia and gastroenterology and advanced/transplant hepatology fellowships at UCSF. She has been recognized as a Fellow of the American Society of Transplantation (FAST). She serves as Associate Editor for the American Journal of Transplantation and is a member for the Editorial Boards for Hepatology and for Liver Transplantation. She currently serves as a standing member on the FDA Gastrointestinal Drug Advisory Committee (2018-2021).

    Collapse Research 
    Collapse Research Activities and Funding
    Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation
    NIH/NIA R01AG059183Jun 15, 2018 - May 31, 2023
    Role: Principal Investigator
    Frailty and Functional Status in Older Liver Transplant Patients
    NIH/NIA K23AG048337Sep 15, 2014 - Apr 30, 2019
    Role: Principal Investigator
    Global Functional Status in the Older Liver Transplant Candidate
    NIH/NIA R03AG045072Aug 15, 2013 - Jul 31, 2015
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites
    Collapse In The News
    Collapse Faculty Mentoring
    Collapse Student Projects
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Rubin JB, Sundaram V, Lai JC. Gender Differences Among Patients Hospitalized With Cirrhosis in the United States. J Clin Gastroenterol. 2020 Jan; 54(1):83-89. PMID: 30807399.
      View in: PubMed
    2. Cullaro G, Verna EC, Lee BP, Lai JC. Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post-Liver Transplant Outcomes. Liver Transpl. 2019 Nov 29. PMID: 31785069.
      View in: PubMed
    3. Fozouni L, Wang CW, Lai JC. Sex Differences in the Association Between Frailty and Sarcopenia in Patients With Cirrhosis. Clin Transl Gastroenterol. 2019 Nov 25. PMID: 31789932.
      View in: PubMed
    4. Ge J, Perito ER, Bucuvalas J, Gilroy R, Hsu EK, Roberts JP, Lai JC. Split liver transplantation is utilized infrequently and concentrated at few transplant centers in the United States. Am J Transplant. 2019 Nov 09. PMID: 31705730.
      View in: PubMed
    5. Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M, Lai JC. Sarcopenia Predicts Post-transplant Mortality in Acutely Ill Men Undergoing Urgent Evaluation and Liver Transplantation. Transplantation. 2019 Nov; 103(11):2312-2317. PMID: 30985575.
      View in: PubMed
    6. Lai JC, Dodge JL, McCulloch CE, Covinsky KE, Singer JP. Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study. Hepatol Commun. 2020 Jan; 4(1):126-133. PMID: 31909360.
      View in: PubMed
    7. Fozouni L, Mohamad Y, Lebsack A, Freise C, Stock P, Lai JC. Frailty is Associated with Increased Rates of Acute Cellular Rejection Within 3 Months After Liver Transplantation. Liver Transpl. 2019 Oct 26. PMID: 31655014.
      View in: PubMed
    8. Cullaro G, Rubin JB, Mehta N, Lai JC. Differential Impact of Age Among Liver Transplant Candidates With and Without Hepatocellular Carcinoma. Liver Transpl. 2019 Oct 14. PMID: 31610089.
      View in: PubMed
    9. Ge J, Lai JC. Identifying a clinically relevant cutoff for height that is associated with a higher risk of waitlist mortality in liver transplant candidates. Am J Transplant. 2019 Oct 09. PMID: 31597006.
      View in: PubMed
    10. Rubin JB, Srisengfa YT, Albhaisi S, Acharya C, Nangia G, Shaikh T, Thacker LR, Reddy KR, Tandon P, Bajaj JS, Lai JC. Hospitalized Women With Cirrhosis Have More Nonhepatic Comorbidities and Associated Complications Than Men. Clin Gastroenterol Hepatol. 2019 Oct 05. PMID: 31593766.
      View in: PubMed
    11. Haugen CE, McAdams-DeMarco M, Verna EC, Rahimi R, Kappus MR, Dunn MA, Volk ML, Gurakar A, Duarte-Rojo A, Ganger DR, O'Leary JG, Ladner D, Garonzik-Wang J, Segev DL, Lai JC. Association Between Liver Transplant Wait-list Mortality and Frailty Based on Body Mass Index. JAMA Surg. 2019 Sep 11. PMID: 31509169.
      View in: PubMed
    12. Williams FR, Berzigotti A, Lord JM, Lai JC, Armstrong MJ. Review article: impact of exercise on physical frailty in patients with chronic liver disease. Aliment Pharmacol Ther. 2019 Nov; 50(9):988-1000. PMID: 31502264.
      View in: PubMed
    13. Mazumder N, Atiemo K, Kappus M, Cullaro G, Harinstein ME, Ladner D, Verna E, Lai J, Levitsky J. A Comprehensive Review of Outcome Predictors in Low MELD Patients. Transplantation. 2019 Sep 09. PMID: 31517785.
      View in: PubMed
    14. Godfrey EL, Malik TH, Lai JC, Mindikoglu AL, Galván NTN, Cotton RT, O'Mahony CA, Goss JA, Rana A. The decreasing predictive power of MELD in an era of changing etiology of liver disease. Am J Transplant. 2019 Dec; 19(12):3299-3307. PMID: 31394020.
      View in: PubMed
    15. Carey EJ, Lai JC, Sonnenday C, Tapper EB, Tandon P, Duarte-Rojo A, Dunn MA, Tsien C, Kallwitz ER, Ng V, Dasarathy S, Kappus M, Bashir MR, Montano-Loza AJ. A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation. Hepatology. 2019 Nov; 70(5):1816-1829. PMID: 31220351.
      View in: PubMed
    16. Ng VL, Mazariegos GV, Kelly B, Horslen S, McDiarmid SV, Magee JC, Loomes KM, Fischer RT, Sundaram SS, Lai JC, Te HS, Bucuvalas JC. Barriers to ideal outcomes after pediatric liver transplantation. Pediatr Transplant. 2019 Sep; 23(6):e13537. PMID: 31343109.
      View in: PubMed
    17. Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Biggins SW, Lai JC, Vargas HE, Maliakkal B, Fallon MB, Thuluvath PJ, Subramanian RM, Thacker LR, Reddy KR. Nosocomial Infections Are Frequent and Negatively Impact Outcomes in Hospitalized Patients With Cirrhosis. Am J Gastroenterol. 2019 Jul; 114(7):1091-1100. PMID: 31180922.
      View in: PubMed
    18. Kohi MP, Lai JC. Impact of Muscle Gain after Transjugular Intrahepatic Portosystemic Shunt Creation on Patients Awaiting Liver Transplantation. J Vasc Interv Radiol. 2019 06; 30(6):874-875. PMID: 31126599.
      View in: PubMed
    19. Lai JC, Sonnenday CJ, Tapper EB, Duarte-Rojo A, Dunn MA, Bernal W, Carey EJ, Dasarathy S, Kamath BM, Kappus MR, Montano-Loza AJ, Nagai S, Tandon P. Frailty in liver transplantation: An expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice. Am J Transplant. 2019 Jul; 19(7):1896-1906. PMID: 30980701.
      View in: PubMed
    20. Ge J, Lai JC. Split-Liver Allocation: An Underused Opportunity to Expand Access to Liver Transplantation. Liver Transpl. 2019 May; 25(5):690-691. PMID: 30920162.
      View in: PubMed
    21. Cullaro G, Hirose R, Lai JC. Changes in Simultaneous Liver-kidney Transplant Allocation Policy May Impact Postliver Transplant Outcomes. Transplantation. 2019 05; 103(5):959-964. PMID: 30086097.
      View in: PubMed
    22. Wang CW, Lebsack A, Chau S, Lai JC. The Range and Reproducibility of the Liver Frailty Index. Liver Transpl. 2019 Jun; 25(6):841-847. PMID: 30884128.
      View in: PubMed
    23. Wong F, Reddy KR, O'Leary JG, Tandon P, Biggins SW, Garcia-Tsao G, Maliakkal BJ, Lai JC, Fallon MB, Vargas HE, Subramanian R, Thuluvath PJ, Kamath PS, Thacker L, Bajaj JS. Impact of Chronic Kidney Disease on Outcomes in Cirrhosis. Liver Transpl. 2019 Jun; 25(6):870-880. PMID: 30908855.
      View in: PubMed
    24. Bajaj JS, Tandon P, O'Leary JG, Wong F, Biggins SW, Garcia-Tsao G, Kamath PS, Maliakkal B, Fallon MB, Lai JC, Thuluvath PJ, Vargas HE, Subramanian RM, Thacker LR, Reddy KR. Outcomes in Patients With Cirrhosis on Primary Compared to Secondary Prophylaxis for Spontaneous Bacterial Peritonitis. Am J Gastroenterol. 2019 Apr; 114(4):599-606. PMID: 30694868.
      View in: PubMed
    25. O'Leary JG, Bajaj JS, Tandon P, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Reddy KR. Outcomes After Listing for Liver Transplant in Patients With Acute-on-Chronic Liver Failure: The Multicenter North American Consortium for the Study of End-Stage Liver Disease Experience. Liver Transpl. 2019 04; 25(4):571-579. PMID: 30724010.
      View in: PubMed
    26. Rubin JB, Sinclair M, Rahimi RS, Tapper EB, Lai JC. Women on the liver transplantation waitlist are at increased risk of hospitalization compared to men. World J Gastroenterol. 2019 Feb 28; 25(8):980-988. PMID: 30833803.
      View in: PubMed
    27. Ge J, Hsu EK, Bucuvalas J, Lai JC. Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation. Hepatology. 2019 Mar; 69(3):1231-1241. PMID: 30281806.
      View in: PubMed
    28. Cullaro G, Verna EC, Lai JC. Association Between Renal Function Pattern and Mortality in Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2019 Oct; 17(11):2364-2370. PMID: 30716479.
      View in: PubMed
    29. Lai JC, Rahimi RS, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'Leary JG, Dodge JL, Ladner D, Segev DL. Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study. Gastroenterology. 2019 05; 156(6):1675-1682. PMID: 30668935.
      View in: PubMed
    30. Haugen CE, McAdams-DeMarco M, Holscher CM, Ying H, Gurakar AO, Garonzik-Wang J, Cameron AM, Segev DL, Lai JC. Multicenter Study of Age, Frailty, and Waitlist Mortality Among Liver Transplant Candidates. Ann Surg. 2019 Jan 18. PMID: 30672803.
      View in: PubMed
    31. Perito ER, Bucuvalas J, Lai JC. Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates. Am J Transplant. 2019 May; 19(5):1388-1396. PMID: 30506640.
      View in: PubMed
    32. Kobashigawa J, Dadhania D, Bhorade S, Adey D, Berger J, Bhat G, Budev M, Duarte-Rojo A, Dunn M, Hall S, Harhay MN, Johansen KL, Joseph S, Kennedy CC, Kransdorf E, Lentine KL, Lynch RJ, McAdams-DeMarco M, Nagai S, Olymbios M, Patel J, Pinney S, Schaenman J, Segev DL, Shah P, Singer LG, Singer JP, Sonnenday C, Tandon P, Tapper E, Tullius SG, Wilson M, Zamora M, Lai JC. Report from the American Society of Transplantation on frailty in solid organ transplantation. Am J Transplant. 2019 Apr; 19(4):984-994. PMID: 30506632.
      View in: PubMed
    33. Sarkar M, Lai JC, Sawinski D, Zeigler TE, Cedars M, Forde KA. Sex hormone levels by presence and severity of cirrhosis in women with chronic hepatitis C virus infection. J Viral Hepat. 2019 Feb; 26(2):258-262. PMID: 30339729.
      View in: PubMed
    34. Lai JC, Tandon P. How I Approach It: Improving Nutritional Status in Patients With Cirrhosis. Am J Gastroenterol. 2018 11; 113(11):1574-1576. PMID: 29867180.
      View in: PubMed
    35. Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR, Dunn MA, Carey EJ, Montano-Loza AJ. Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis. J Cachexia Sarcopenia Muscle. 2018 12; 9(6):1053-1062. PMID: 30269421.
      View in: PubMed
    36. Bajaj JS, Moreau R, Kamath PS, Vargas HE, Arroyo V, Reddy KR, Szabo G, Tandon P, Olson J, Karvellas C, Gustot T, Lai JC, Wong F. Acute-on-Chronic Liver Failure: Getting Ready for Prime Time? Hepatology. 2018 10; 68(4):1621-1632. PMID: 29689120.
      View in: PubMed
    37. Kuo SZ, Lizaola B, Hayssen H, Lai JC. Beta-blockers and physical frailty in patients with end-stage liver disease. World J Gastroenterol. 2018 Sep 07; 24(33):3770-3775. PMID: 30197482.
      View in: PubMed
    38. Chascsa DM, Lai JC, Dunn MA, Montano-Loza AJ, Kappus MR, Dasarathy S, Carey EJ. Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation. Dig Dis Sci. 2018 12; 63(12):3290-3296. PMID: 30178285.
      View in: PubMed
    39. Schwartz JB, Gallagher JC, Jorde R, Berg V, Walsh J, Eastell R, Evans AL, Bowles S, Naylor KE, Jones KS, Schoenmakers I, Holick M, Orwoll E, Nielson C, Kaufmann M, Jones G, Bouillon R, Lai J, Verotta D, Bikle D. Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations. J Clin Endocrinol Metab. 2018 09 01; 103(9):3278-3288. PMID: 29955795.
      View in: PubMed
    40. Bajaj JS, Vargas HE, Reddy KR, Lai JC, O'Leary JG, Tandon P, Wong F, Mitrani R, White MB, Kelly M, Fagan A, Patil R, Sait S, Sikaroodi M, Thacker LR, Gillevet PM. Association Between Intestinal Microbiota Collected at Hospital Admission and Outcomes of Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2019 Mar; 17(4):756-765.e3. PMID: 30036646.
      View in: PubMed
    41. Cullaro G, Park M, Lai JC. "Normal" Creatinine Levels Predict Persistent Kidney Injury and Waitlist Mortality in Outpatients With Cirrhosis. Hepatology. 2018 11; 68(5):1953-1960. PMID: 29698588.
      View in: PubMed
    42. Bajaj JS, Tandon P, O'Leary JG, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai JC, Fallon M, Thuluvath P, Vargas HE, Subramanian RM, Thacker LR, Reddy RK. The Impact of Albumin Use on Resolution of Hyponatremia in Hospitalized Patients With Cirrhosis. Am J Gastroenterol. 2018 09; 113(9):1339. PMID: 29880972.
      View in: PubMed
    43. Ge J, Gilroy R, Lai JC. Receipt of a pediatric liver offer as the first offer reduces waitlist mortality for adult women. Hepatology. 2018 09; 68(3):1101-1110. PMID: 29604217.
      View in: PubMed
    44. Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S. Reply. Hepatology. 2018 05; 67(5):2059-2060. PMID: 29377206.
      View in: PubMed
    45. Reuter B, Walter K, Bissonnette J, Leise MD, Lai J, Tandon P, Kamath PS, Biggins SW, Rose CF, Wade JB, Bajaj JS. Assessment of the spectrum of hepatic encephalopathy: A multicenter study. Liver Transpl. 2018 05; 24(5):587-594. PMID: 29457869.
      View in: PubMed
    46. O'Leary JG, Reddy KR, Garcia-Tsao G, Biggins SW, Wong F, Fallon MB, Subramanian RM, Kamath PS, Thuluvath P, Vargas HE, Maliakkal B, Tandon P, Lai J, Thacker LR, Bajaj JS. NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis. Hepatology. 2018 06; 67(6):2367-2374. PMID: 29315693.
      View in: PubMed
    47. Lai JC, Segev DL, McCulloch CE, Covinsky KE, Dodge JL, Feng S. Physical frailty after liver transplantation. Am J Transplant. 2018 08; 18(8):1986-1994. PMID: 29380529.
      View in: PubMed
    48. Puchades L, Chau S, Dodson JA, Mohamad Y, Mustain R, Lebsack A, Aguilera V, Prieto M, Lai JC. Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist: From the Functional Assessment in Liver Transplantation Study. Transplantation. 2018 03; 102(3):e101-e107. PMID: 29189486.
      View in: PubMed
    49. Lockett H, Lai J, Tuason C, Jury A, Fergusson D. Primary healthcare utilisation among adults with mood and anxiety disorders: an analysis of the New Zealand Health Survey. J Prim Health Care. 2018 03; 10(1):68-75. PMID: 30068454.
      View in: PubMed
    50. Ge J, Roberts JP, Lai JC. A2 liver transplantation across the ABO barrier: Increasing options in the donor pool? Clin Liver Dis (Hoboken). 2017 Dec; 10(6):135-138. PMID: 30992773.
      View in: PubMed
    51. Cullaro G, Sarkar M, Lai JC. Sex-based disparities in delisting for being "too sick" for liver transplantation. Am J Transplant. 2018 05; 18(5):1214-1219. PMID: 29194969.
      View in: PubMed
    52. Bajaj JS, Reddy RK, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Fallon M, Maliakkal B, Lai J, Vargas HE, Subramanian RM, Thuluvath P, Thacker LR, O'Leary JG. Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort. Am J Gastroenterol. 2018 04; 113(4):556-563. PMID: 29257141.
      View in: PubMed
    53. Lai JC, Covinsky KE, McCulloch CE, Feng S. The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis. Am J Gastroenterol. 2018 02; 113(2):235-242. PMID: 29231189.
      View in: PubMed
    54. Fleming JN, Lai JC, Te HS, Said A, Spengler EK, Rogal SS. Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices. Clin Transplant. 2017 Dec; 31(12). PMID: 28941292.
      View in: PubMed
    55. Spengler EK, O'Leary JG, Te HS, Rogal S, Pillai AA, Al-Osaimi A, Desai A, Fleming JN, Ganger D, Seetharam A, Tsoulfas G, Montenovo M, Lai JC. Liver Transplantation in the Obese Cirrhotic Patient. Transplantation. 2017 10; 101(10):2288-2296. PMID: 28930104.
      View in: PubMed
    56. C Lai J. Transplant for the very sick: No limitations in donor quality? Liver Transpl. 2017 10; 23(S1):S40-S43. PMID: 28734123.
      View in: PubMed
    57. Hsu EK, Shaffer ML, Gao L, Sonnenday C, Volk ML, Bucuvalas J, Lai JC. Analysis of Liver Offers to Pediatric Candidates on the Transplant Wait List. Gastroenterology. 2017 10; 153(4):988-995. PMID: 28711630.
      View in: PubMed
    58. Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S. Development of a novel frailty index to predict mortality in patients with end-stage liver disease. Hepatology. 2017 08; 66(2):564-574. PMID: 28422306.
      View in: PubMed
    59. Ge J, Roberts JP, Lai JC. Race/ethnicity is associated with ABO-nonidentical liver transplantation in the United States. Clin Transplant. 2017 08; 31(8). PMID: 28517242.
      View in: PubMed
    60. Wang CW, Lai JC. Reporting functional status in UNOS: The weakness of the Karnofsky Performance Status Scale. Clin Transplant. 2017 07; 31(7). PMID: 28580753.
      View in: PubMed
    61. Carey EJ, Lai JC, Wang CW, Dasarathy S, Lobach I, Montano-Loza AJ, Dunn MA. A multicenter study to define sarcopenia in patients with end-stage liver disease. Liver Transpl. 2017 05; 23(5):625-633. PMID: 28240805.
      View in: PubMed
    62. Salazar J, Saxena V, Kahn JG, Roberts JP, Mehta N, Volk M, Lai JC. Cost-Effectiveness of Direct-Acting Antiviral Treatment in Hepatitis C-Infected Liver Transplant Candidates With Compensated Cirrhosis and Hepatocellular Carcinoma. Transplantation. 2017 05; 101(5):1001-1008. PMID: 27926593.
      View in: PubMed
    63. Samoylova ML, Covinsky KE, Haftek M, Kuo S, Roberts JP, Lai JC. Disability in patients with end-stage liver disease: Results from the functional assessment in liver transplantation study. Liver Transpl. 2017 03; 23(3):292-298. PMID: 27884053.
      View in: PubMed
    64. Sinclair M, Poltavskiy E, Dodge JL, Lai JC. Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist. World J Gastroenterol. 2017 Feb 07; 23(5):899-905. PMID: 28223735.
      View in: PubMed
    65. Clinical Liver Disease. A framework to determine when liver transplantation is futile. 2016; 8:137-9.
      View Publication
    66. Lai JC. A framework to determine when liver transplantation is futile. Clin Liver Dis (Hoboken). 2016 Dec; 8(6):137-139. PMID: 30294424.
      View in: PubMed
    67. Pavasini R, Guralnik J, Brown JC, di Bari M, Cesari M, Landi F, Vaes B, Legrand D, Verghese J, Wang C, Stenholm S, Ferrucci L, Lai JC, Bartes AA, Espaulella J, Ferrer M, Lim JY, Ensrud KE, Cawthon P, Turusheva A, Frolova E, Rolland Y, Lauwers V, Corsonello A, Kirk GD, Ferrari R, Volpato S, Campo G. Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis. BMC Med. 2016 Dec 22; 14(1):215. PMID: 28003033.
      View in: PubMed
    68. Kuo SZ, Haftek M, Lai JC. Factors Associated with Medication Non-adherence in Patients with End-Stage Liver Disease. Dig Dis Sci. 2017 02; 62(2):543-549. PMID: 27933471.
      View in: PubMed
    69. Lai JC. Editorial: Advancing Adoption of Frailty to Improve the Care of Patients with Cirrhosis: Time for a Consensus on a Frailty Index. Am J Gastroenterol. 2016 12; 111(12):1776-1777. PMID: 27924103.
      View in: PubMed
    70. Lai JC, Volk ML, Strasburg D, Alexander N. Performance-Based Measures Associate With Frailty in Patients With End-Stage Liver Disease. Transplantation. 2016 Dec; 100(12):2656-2660. PMID: 27495749.
      View in: PubMed
    71. Giard JM, Decker KA, Lai JC, Gill RM, Logan AC, Fix OK. Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy. ACG Case Rep J. 2016 Aug; 3(4):e162. PMID: 27921061.
      View in: PubMed
    72. Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Maliakkal B, Biggins SW, Thuluvath PJ, Fallon MB, Subramanian RM, Vargas HE, Lai J, Thacker LR, Reddy KR. Hepatic Encephalopathy Is Associated With Mortality in Patients With Cirrhosis Independent of Other Extrahepatic Organ Failures. Clin Gastroenterol Hepatol. 2017 Apr; 15(4):565-574.e4. PMID: 27720916.
      View in: PubMed
    73. Kathpalia P, Smith A, Lai JC. Underutilization of palliative care services in the liver transplant population. World J Transplant. 2016 Sep 24; 6(3):594-8. PMID: 27683638.
      View in: PubMed
    74. Wang CW, Feng S, Covinsky KE, Hayssen H, Zhou LQ, Yeh BM, Lai JC. A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates: Results From the Functional Assessment in Liver Transplantation Study. Transplantation. 2016 Aug; 100(8):1692-8. PMID: 27314169.
      View in: PubMed
    75. Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge J, Roberts JP, Terrault NA, Feng S. Response to clinical assessments of health status as a potential marker to identify patients who are too sick to undergo transplantation. Liver Int. 2016 Apr; 36(4):611. PMID: 26584013.
      View in: PubMed
    76. Lai JC, Roberts JP. ABO-Nonidentical Liver Transplantation in the United States. Am J Transplant. 2016 08; 16(8):2430-6. PMID: 26932134.
      View in: PubMed
    77. Lai JC. Defining the threshold for too sick for transplant. Curr Opin Organ Transplant. 2016 Apr; 21(2):127-32. PMID: 26825359.
      View in: PubMed
    78. Lai JC, Dodge JL, Sen S, Covinsky K, Feng S. Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study. Hepatology. 2016 Feb; 63(2):574-80. PMID: 26517301.
      View in: PubMed
    79. Wang CW, Covinsky KE, Feng S, Hayssen H, Segev DL, Lai JC. Functional impairment in older liver transplantation candidates: From the functional assessment in liver transplantation study. Liver Transpl. 2015 Dec; 21(12):1465-70. PMID: 26359787.
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    80. Kwong AJ, Lai JC, Dodge JL, Roberts JP. Outcomes for liver transplant candidates listed with low model for end-stage liver disease score. Liver Transpl. 2015 Nov; 21(11):1403-9. PMID: 26289624.
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    81. Saxena V, Lai JC. Kidney Failure and Liver Allocation: Current Practices and Potential Improvements. Adv Chronic Kidney Dis. 2015 Sep; 22(5):391-8. PMID: 26311601.
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    82. Volk ML, Goodrich N, Lai JC, Sonnenday C, Shedden K. Decision support for organ offers in liver transplantation. Liver Transpl. 2015 Jun; 21(6):784-91. PMID: 25779757.
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    83. Campos-Varela I, Lai JC, Verna EC, O'Leary JG, Todd Stravitz R, Forman LM, Trotter JF, Brown RS, Terrault NA. Hepatitis C genotype influences post-liver transplant outcomes. Transplantation. 2015 Apr; 99(4):835-40. PMID: 25211520.
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    84. Lai JC, Bikle DD, Lizaola B, Hayssen H, Terrault NA, Schwartz JB. Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction. Liver Int. 2015 Oct; 35(10):2294-300. PMID: 25757956.
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    85. Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge JL, Roberts JP, Terrault NA, Feng S. Clinician assessments of health status predict mortality in patients with end-stage liver disease awaiting liver transplantation. Liver Int. 2015 Sep; 35(9):2167-73. PMID: 25644788.
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    86. Lai JC, Shoback DM, Zipperstein J, Lizaola B, Tseng S, Terrault NA. Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C. Dig Dis Sci. 2015 Jun; 60(6):1813-9. PMID: 25563723.
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    87. Bissell DM, Lai JC, Meister RK, Blanc PD. Role of delta-aminolevulinic acid in the symptoms of acute porphyria. Am J Med. 2015 Mar; 128(3):313-7. PMID: 25446301.
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    88. Sharpton SR, Feng S, Hameed B, Yao F, Lai JC. Combined effects of recipient age and model for end-stage liver disease score on liver transplantation outcomes. Transplantation. 2014 Sep 15; 98(5):557-62. PMID: 24717221.
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    89. Lai JC, Covinsky K, Feng S. The octogenarian donor: can the liver be "younger than stated age"? Am J Transplant. 2014 Sep; 14(9):1962-3. PMID: 25307032.
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    90. Feng S, Lai JC. Expanded criteria donors. Clin Liver Dis. 2014 Aug; 18(3):633-49. PMID: 25017080.
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    91. Lai JC, Feng S, Terrault NA, Lizaola B, Hayssen H, Covinsky K. Frailty predicts waitlist mortality in liver transplant candidates. Am J Transplant. 2014 Aug; 14(8):1870-9. PMID: 24935609.
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    92. Schwartz JB, Lai J, Lizaola B, Kane L, Markova S, Weyland P, Terrault NA, Stotland N, Bikle D. A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations. J Clin Endocrinol Metab. 2014 May; 99(5):1631-7. PMID: 24483159.
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    93. Schwartz JB, Lai J, Lizaola B, Kane L, Weyland P, Terrault NA, Stotland N, Bikle D. Variability in free 25(OH) vitamin D levels in clinical populations. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:156-8. PMID: 24240067.
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    94. Lai JC, Kahn JG, Tavakol M, Peters MG, Roberts JP. Reducing infection transmission in solid organ transplantation through donor nucleic acid testing: a cost-effectiveness analysis. Am J Transplant. 2013 Oct; 13(10):2611-8. PMID: 24034208.
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    95. Lai JC, Feng S, Vittinghoff E, Roberts JP. Offer patterns of nationally placed livers by donation service area. Liver Transpl. 2013 Apr; 19(4):404-10. PMID: 23447450.
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    96. Halldorson JB, Paarsch HJ, Dodge JL, Segre AM, Lai J, Roberts JP. Center competition and outcomes following liver transplantation. Liver Transpl. 2013 Jan; 19(1):96-104. PMID: 23086897.
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    97. Lai JC, Feng S, Roberts JP. An examination of liver offers to candidates on the liver transplant wait-list. Gastroenterology. 2012 Nov; 143(5):1261-1265. PMID: 22841780.
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    98. Lai JC, O'Leary JG, Trotter JF, Verna EC, Brown RS, Stravitz RT, Duman JD, Forman LM, Terrault NA. Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study. Liver Transpl. 2012 May; 18(5):532-8. PMID: 22271671.
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    99. Saxena V, Lai JC, O'Leary JG, Verna EC, Brown RS, Stravitz RT, Trotter JF, Krishnan K, Terrault NA. Recipient-donor race mismatch for African American liver transplant patients with chronic hepatitis C. Liver Transpl. 2012 May; 18(5):524-31. PMID: 22140019.
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    100. Verna EC, Valadao R, Farrand E, Pichardo EM, Lai JC, Terrault NA, Brown RS. Effects of ethnicity and socioeconomic status on survival and severity of fibrosis in liver transplant recipients with hepatitis C virus. Liver Transpl. 2012 Apr; 18(4):461-7. PMID: 22467547.
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    101. Lai JC, Roberts JP, Vittinghoff E, Terrault NA, Feng S. Patient, center and geographic characteristics of nationally placed livers. Am J Transplant. 2012 Apr; 12(4):947-53. PMID: 22300591.
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    102. Brandman D, Pingitore A, Lai JC, Roberts JP, Ferrell L, Bass NM, Terrault NA. Hepatic steatosis at 1 year is an additional predictor of subsequent fibrosis severity in liver transplant recipients with recurrent hepatitis C virus. Liver Transpl. 2011 Dec; 17(12):1380-6. PMID: 21770018.
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    103. Lai JC, Verna EC, Brown RS, O'Leary JG, Trotter JF, Forman LM, Duman JD, Foster RG, Stravitz RT, Terrault NA. Hepatitis C virus-infected women have a higher risk of advanced fibrosis and graft loss after liver transplantation than men. Hepatology. 2011 Aug; 54(2):418-24. PMID: 21538434.
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    104. Lai JC, Feng S, Roberts JP, Terrault NA. Gender differences in liver donor quality are predictive of graft loss. Am J Transplant. 2011 Feb; 11(2):296-302. PMID: 21219572.
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    105. Lai JC, Terrault NA, Vittinghoff E, Biggins SW. Height contributes to the gender difference in wait-list mortality under the MELD-based liver allocation system. Am J Transplant. 2010 Dec; 10(12):2658-64. PMID: 21087414.
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    106. Monto A, Schooley RT, Lai JC, Sulkowski MS, Chung RT, Pawlotsky JM, McHutchison JG, Jacobson IM. Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop. Am J Gastroenterol. 2010 May; 105(5):989-1004; quiz 988, 1005. PMID: 20087331.
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    107. Lai JC, Montero A, Lebwohl B, Brown RS. A novel housestaff educational model for quaternary-care patients at an academic health center. Acad Med. 2009 Feb; 84(2):206-11. PMID: 19174667.
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    108. Lai JC, Pichardo EM, Emond JC, Brown RS. Resource utilization of living donor versus deceased donor liver transplantation is similar at an experienced transplant center. Am J Transplant. 2009 Mar; 9(3):586-91. PMID: 19191773.
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