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Carl Grunfeld, MD, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentMedicine
Address111F
Phone415-750-2005
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    Collapse Research 
    Collapse Research Activities and Funding
    Effects of Antiretroviral Drugs on Metabolism
    NIH/NIDDK R01DK066999Mar 1, 2004 - Jan 31, 2013
    Role: Principal Investigator
    Fat Redistribution and Metabolic Change in HIV Infection
    NIH/NHLBI R01HL074814Sep 30, 1999 - Aug 31, 2009
    Role: Principal Investigator
    FAT REDISTRIBUTION AND METABOLIC CHANGE IN HIV INFECTION
    NIH/NIDDK R01DK057508Sep 30, 1999 - Sep 25, 2003
    Role: Principal Investigator
    ROLE OF SECONDARY ILLNESS IN THE WASTING OF AIDS
    NIH/NIDDK R01DK049448Sep 30, 1994 - Jul 31, 2002
    Role: Principal Investigator
    The Connie Wofsy Women's HIV Study
    NIH/NIAID U01AI034989Aug 1, 1993 - Dec 31, 2018
    Role: Co-Investigator
    CYTOKINES AND HYPERLIPIDEMIA AND WASTING OF AIDS
    NIH/NIDDK R01DK040990Jul 1, 1989 - Jun 30, 1998
    Role: Principal Investigator
    INSULIN RECEPTOR STRUCTURE AND FUNCTION
    NIH/NIDDK R01DK037102Apr 1, 1986 - Mar 31, 1990
    Role: Principal Investigator
    A Resource for Biomedical Mass Spectrometry
    NIH P41RR000954Jun 1, 1975 - Dec 31, 2014
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Scherzer R, Shah SJ, Secemsky E, Butler J, Grunfeld C, Shlipak MG, Hsue PY. Association of Biomarker Clusters With Cardiac Phenotypes and Mortality in Patients With HIV Infection. Circ Heart Fail. 2018 Apr; 11(4):e004312. PMID: 29615435.
      View in: PubMed
    2. Reid M, Ma Y, Scherzer R, Price JC, French AL, Huhn GD, Plankey MW, Peters M, Grunfeld C, Tien PC. Contribution of Liver Fibrosis and Microbial Translocation to Immune Activation in Persons Infected With HIV and/or Hepatitis C Virus. J Infect Dis. 2018 Mar 28; 217(8):1289-1297. PMID: 29304196.
      View in: PubMed
    3. Chau KH, Scherzer R, Grunfeld C, Hsue PY, Shlipak MG. CHA2DS2-VASc Score, Warfarin Use, and Risk for Thromboembolic Events Among HIV-Infected Persons With Atrial Fibrillation. J Acquir Immune Defic Syndr. 2017 09 01; 76(1):90-97. PMID: 28797024.
      View in: PubMed
    4. Chen R, Scherzer R, Hsue PY, Jotwani V, Estrella MM, Horberg MA, Grunfeld C, Shlipak MG. Association of Tenofovir Use With Risk of Incident Heart Failure in HIV-Infected Patients. J Am Heart Assoc. 2017 Apr 24; 6(4). PMID: 28438737.
      View in: PubMed
    5. Crane HM, Paramsothy P, Drozd DR, Nance RM, Delaney JA, Heckbert SR, Budoff MJ, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, Rodriguez C, Peter I, Barnes GS, McReynolds J, Lober WB, Crothers K, Feinstein MJ, Grunfeld C, Saag MS, Kitahata MM. Types of Myocardial Infarction Among Human Immunodeficiency Virus-Infected Individuals in the United States. JAMA Cardiol. 2017 Mar 01; 2(3):260-267. PMID: 28052152.
      View in: PubMed
    6. Noorhasan M, Drozd DR, Grunfeld C, Merrill JO, Burkholder GA, Mugavero MJ, Willig JH, Willig AL, Cropsey KL, Mayer KH, Blashill A, Mimiaga M, McCaul ME, Hutton H, Chander G, Mathews WC, Napravnik S, Eron JJ, Christopoulos K, Fredericksen RJ, Nance RM, Delaney JC, Crane PK, Saag MS, Kitahata MM, Crane HM. Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV. AIDS Res Hum Retroviruses. 2017 Feb 16. PMID: 28092168.
      View in: PubMed
    7. Reid M, Ma Y, Scherzer R, Price JC, French AL, Plankey MW, Grunfeld C, Tien PC. Higher CD163 levels are associated with insulin resistance in hepatitis C virus-infected and HIV-infected adults. AIDS. 2017 Jan 28; 31(3):385-393. PMID: 28081037.
      View in: PubMed
    8. Scherzer R, Heymsfield SB, Rimland D, Powderly WG, Tien PC, Bacchetti P, Shlipak MG, Grunfeld C. Association of serum albumin and aspartate transaminase with 5-year all-cause mortality in HIV/hepatitis C virus coinfection and HIV monoinfection. AIDS. 2017 Jan 02; 31(1):71-79. PMID: 27677166.
      View in: PubMed
    9. Ascher SB, Scherzer R, Peralta CA, Tien PC, Grunfeld C, Estrella MM, Abraham A, Gustafson DR, Nowicki M, Sharma A, Cohen MH, Butch AW, Young MA, Bennett MR, Shlipak MG. Association of Kidney Function and Early Kidney Injury With Incident Hypertension in HIV-Infected Women. Hypertension. 2017 02; 69(2):304-313. PMID: 27993956.
      View in: PubMed
    10. Feingold KR, Grunfeld C. Effect of inflammation on HDL structure and function. Curr Opin Lipidol. 2016 Oct; 27(5):521-30. PMID: 27495134.
      View in: PubMed
    11. Grunfeld C, Dankner R. Diabetes in HIV-infected persons in Cameroon? Diabetes Metab Res Rev. 2016 09; 32(6):512-3. PMID: 26936763.
      View in: PubMed
    12. Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY. HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". J Am Heart Assoc. 2016 Apr 29; 5(5). PMID: 27130349; PMCID: PMC4889164.
    13. Daubenmier J, Moran PJ, Kristeller J, Acree M, Bacchetti P, Kemeny ME, Dallman M, Lustig RH, Grunfeld C, Nixon DF, Milush JM, Goldman V, Laraia B, Laugero KD, Woodhouse L, Epel ES, Hecht FM. Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial. Obesity (Silver Spring). 2016 Apr; 24(4):794-804. PMID: 26955895; PMCID: PMC4898945 [Available on 04/01/17].
    14. Tuot DS, Scherzer R, Leong H, Hung AM, Grunfeld C, Shlipak MG. Use of cystatin C to inform metformin eligibility among adult veterans with diabetes. J Clin Transl Endocrinol. 2016 Mar; 3:1-6. PMID: 28603691.
      View in: PubMed
    15. Swanson S, Ma Y, Scherzer R, Huhn G, French AL, Plankey MW, Grunfeld C, Rosenberg WM, Peters MG, Tien PC. Association of HIV, Hepatitis C Virus, and Liver Fibrosis Severity With the Enhanced Liver Fibrosis Score. J Infect Dis. 2016 Apr 01; 213(7):1079-86. PMID: 26621911; PMCID: PMC4779303 [Available on 04/01/17].
    16. Shah S, Ma Y, Scherzer R, Huhn G, French AL, Plankey M, Peters MG, Grunfeld C, Tien PC. Association of HIV, hepatitis C virus and liver fibrosis severity with interleukin-6 and C-reactive protein levels. AIDS. 2015 Jul 17; 29(11):1325-33. PMID: 25870985; PMCID: PMC4478137.
    17. Rao MN, Neylan TC, Grunfeld C, Mulligan K, Schambelan M, Schwarz JM. Subchronic sleep restriction causes tissue-specific insulin resistance. J Clin Endocrinol Metab. 2015 Apr; 100(4):1664-71. PMID: 25658017; PMCID: PMC4399283.
    18. Wheeler AL, Tien PC, Grunfeld C, Schafer AL. Teriparatide treatment of osteoporosis in an HIV-infected man: a case report and literature review. AIDS. 2015 Jan 14; 29(2):245-6. PMID: 25532609; PMCID: PMC4438749.
    19. Zhi D, Shendre A, Scherzer R, Irvin MR, Perry RT, Levy S, Arnett DK, Grunfeld C, Shrestha S. Deep sequencing of RYR3 gene identifies rare and common variants associated with increased carotid intima-media thickness (cIMT) in HIV-infected individuals. J Hum Genet. 2015 Feb; 60(2):63-7. PMID: 25500725.
      View in: PubMed
    20. O'Donovan A, Chao LL, Paulson J, Samuelson KW, Shigenaga JK, Grunfeld C, Weiner MW, Neylan TC. Altered inflammatory activity associated with reduced hippocampal volume and more severe posttraumatic stress symptoms in Gulf War veterans. Psychoneuroendocrinology. 2015 Jan; 51:557-66. PMID: 25465168; PMCID: PMC4374733.
    21. Hsue PY, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J. Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. J Am Heart Assoc. 2014 Oct 21; 3(5):e001267. PMID: 25336464; PMCID: PMC4323827.
    22. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages. J Lipid Res. 2014 Dec; 55(12):2501-8. PMID: 25320346; PMCID: PMC4242443.
    23. Rao MN, Chau A, Madden E, Inslicht S, Talbot L, Richards A, O'Donovan A, Ruoff L, Grunfeld C, Neylan TC. Hyperinsulinemic response to oral glucose challenge in individuals with posttraumatic stress disorder. Psychoneuroendocrinology. 2014 Nov; 49:171-81. PMID: 25108160; PMCID: PMC4165697.
    24. Lang J, Scherzer R, Tien PC, Parikh CR, Anastos K, Estrella MM, Abraham AG, Sharma A, Cohen MH, Butch AW, Nowicki M, Grunfeld C, Shlipak MG. Serum albumin and kidney function decline in HIV-infected women. Am J Kidney Dis. 2014 Oct; 64(4):584-91. PMID: 25059222; PMCID: PMC4177337.
    25. Scherzer R, Gandhi M, Estrella MM, Tien PC, Deeks SG, Grunfeld C, Peralta CA, Shlipak MG. A chronic kidney disease risk score to determine tenofovir safety in a prospective cohort of HIV-positive male veterans. AIDS. 2014 Jun 01; 28(9):1289-95. PMID: 24922479; PMCID: PMC4188545.
    26. Pulliam L, Calosing C, Sun B, Grunfeld C, Rempel H. Monocyte activation from interferon-a in HIV infection increases acetylated LDL uptake and ROS production. J Interferon Cytokine Res. 2014 Oct; 34(10):822-8. PMID: 24731171; PMCID: PMC4186262.
    27. Manenschijn L, Scherzer R, Koper JW, Danoff A, van Rossum EF, Grunfeld C. Association of glucocorticoid receptor haplotypes with body composition and metabolic parameters in HIV-infected patients from the FRAM study. Pharmacogenet Genomics. 2014 Mar; 24(3):156-61. PMID: 24418810.
      View in: PubMed
    28. Wheeler AL, Scherzer R, Lee D, Delaney JA, Bacchetti P, Shlipak MG, Sidney S, Grunfeld C, Tien PC. HIV/hepatitis C virus coinfection ameliorates the atherogenic lipoprotein abnormalities of HIV infection. AIDS. 2014 Jan 02; 28(1):49-58. PMID: 24136113.
      View in: PubMed
    29. Shrestha S, Irvin MR, Grunfeld C, Arnett DK. HIV, inflammation, and calcium in atherosclerosis. Arterioscler Thromb Vasc Biol. 2014 Feb; 34(2):244-50. PMID: 24265418.
      View in: PubMed
    30. Jotwani V, Scherzer R, Abraham A, Estrella MM, Bennett M, Devarajan P, Anastos K, Cohen MH, Nowicki M, Sharma A, Young M, Tien PC, Grunfeld C, Parikh CR, Shlipak MG. Does HIV infection promote early kidney injury in women? Antivir Ther. 2014; 19(1):79-87. PMID: 23970313; PMCID: PMC3933452.
    31. Maguen S, Madden E, Cohen B, Bertenthal D, Neylan T, Talbot L, Grunfeld C, Seal K. The relationship between body mass index and mental health among Iraq and Afghanistan veterans. J Gen Intern Med. 2013 Jul; 28 Suppl 2:S563-70. PMID: 23807066; PMCID: PMC3695271.
    32. Lang J, Scherzer R, Weekley CC, Tien PC, Grunfeld C, Shlipak MG. Serum albumin and short-term risk for mortality and cardiovascular disease among HIV-infected veterans. AIDS. 2013 May 15; 27(8):1339-43. PMID: 23343914; PMCID: PMC4026018.
    33. Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, Deeks SG, Ganz P, Hsue PY. Elevated levels of asymmetric dimethylarginine are associated with lower CD4+ count and higher viral load in HIV-infected individuals. Atherosclerosis. 2013 Jul; 229(1):246-52. PMID: 23711612.
      View in: PubMed
    34. Hsu JC, Li Y, Marcus GM, Hsue PY, Scherzer R, Grunfeld C, Shlipak MG. Atrial fibrillation and atrial flutter in human immunodeficiency virus-infected persons: incidence, risk factors, and association with markers of HIV disease severity. J Am Coll Cardiol. 2013 Jun 04; 61(22):2288-95. PMID: 23563125.
      View in: PubMed
    35. Jiang YJ, Kim P, Uchida Y, Elias PM, Bikle DD, Grunfeld C, Feingold KR. Ceramides stimulate caspase-14 expression in human keratinocytes. Exp Dermatol. 2013 Feb; 22(2):113-8. PMID: 23362869; PMCID: PMC4099380.
    36. Shlipak MG, Scherzer R, Abraham A, Tien PC, Grunfeld C, Peralta CA, Devarajan P, Bennett M, Butch AW, Anastos K, Cohen MH, Nowicki M, Sharma A, Young MA, Sarnak MJ, Parikh CR. Urinary markers of kidney injury and kidney function decline in HIV-infected women. J Acquir Immune Defic Syndr. 2012 Dec 15; 61(5):565-73. PMID: 23023103; PMCID: PMC3509242.
    37. Feingold KR, Grunfeld C. Lipids: a key player in the battle between the host and microorganisms. J Lipid Res. 2012 Dec; 53(12):2487-9. PMID: 23075464; PMCID: PMC3494250.
    38. Feingold KR, Shigenaga JK, Kazemi MR, McDonald CM, Patzek SM, Cross AS, Moser A, Grunfeld C. Mechanisms of triglyceride accumulation in activated macrophages. J Leukoc Biol. 2012 Oct; 92(4):829-39. PMID: 22753953; PMCID: PMC3441312.
    39. Feingold KR, Grunfeld C. Psoriasis: it's more than just the skin. J Lipid Res. 2012 Aug; 53(8):1427-9. PMID: 22685321; PMCID: PMC3540839.
    40. Scherzer R, Estrella M, Li Y, Choi AI, Deeks SG, Grunfeld C, Shlipak MG. Association of tenofovir exposure with kidney disease risk in HIV infection. AIDS. 2012 Apr 24; 26(7):867-75. PMID: 22313955; PMCID: PMC3736566.
    41. Feingold KR, Shigenaga JK, Cross AS, Moser A, Grunfeld C. Angiopoietin like protein 4 expression is decreased in activated macrophages. Biochem Biophys Res Commun. 2012 May 11; 421(3):612-5. PMID: 22538368.
      View in: PubMed
    42. Feingold KR, Grunfeld C, Heuer JG, Gupta A, Cramer M, Zhang T, Shigenaga JK, Patzek SM, Chan ZW, Moser A, Bina H, Kharitonenkov A. FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis. Endocrinology. 2012 Jun; 153(6):2689-700. PMID: 22474187; PMCID: PMC3359613.
    43. Hsue PY, Scherzer R, Grunfeld C, Nordstrom SM, Schnell A, Kohl LP, Nitta E, Martin JN, Deeks SG, Weiss EJ. HIV infection is associated with decreased thrombin generation. Clin Infect Dis. 2012 Apr; 54(8):1196-203. PMID: 22438347; PMCID: PMC3309887.
    44. Li Y, Shlipak MG, Grunfeld C, Choi AI. Incidence and risk factors for acute kidney injury in HIV Infection. Am J Nephrol. 2012; 35(4):327-34. PMID: 22456100; PMCID: PMC3362304.
    45. Shen W, Scherzer R, Gantz M, Chen J, Punyanitya M, Lewis CE, Grunfeld C. Relationship between MRI-measured bone marrow adipose tissue and hip and spine bone mineral density in African-American and Caucasian participants: the CARDIA study. J Clin Endocrinol Metab. 2012 Apr; 97(4):1337-46. PMID: 22319043; PMCID: PMC3319176.
    46. Jotwani V, Li Y, Grunfeld C, Choi AI, Shlipak MG. Risk factors for ESRD in HIV-infected individuals: traditional and HIV-related factors. Am J Kidney Dis. 2012 May; 59(5):628-35. PMID: 22206742; PMCID: PMC3324595.
    47. Irvin MR, Shrestha S, Chen YD, Wiener HW, Haritunians T, Vaughan LK, Tiwari HK, Taylor KD, Scherzer R, Saag MS, Grunfeld C, Rotter JI, Arnett DK. Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men. Pharmacogenet Genomics. 2011 Dec; 21(12):798-807. PMID: 21897333; PMCID: PMC3210910.
    48. Eastburn A, Scherzer R, Zolopa AR, Benson C, Tracy R, Do T, Bacchetti P, Shlipak M, Grunfeld C, Tien PC. Association of low level viremia with inflammation and mortality in HIV-infected adults. PLoS One. 2011; 6(11):e26320. PMID: 22073156; PMCID: PMC3206804.
    49. Kosmiski LA, Scherzer R, Heymsfield SB, Rimland D, Simberkoff MS, Sidney S, Shlipak MG, Bacchetti P, Biggs ML, Grunfeld C. Association of increased upper trunk and decreased leg fat with 2-h glucose in control and HIV-infected persons. Diabetes Care. 2011 Nov; 34(11):2448-53. PMID: 21926283; PMCID: PMC3198295.
    50. Scherzer R, Heymsfield SB, Lee D, Powderly WG, Tien PC, Bacchetti P, Shlipak MG, Grunfeld C. Decreased limb muscle and increased central adiposity are associated with 5-year all-cause mortality in HIV infection. AIDS. 2011 Jul 17; 25(11):1405-14. PMID: 21572308; PMCID: PMC3933309.
    51. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation inhibits GPR81 expression in adipose tissue. Inflamm Res. 2011 Oct; 60(10):991-5. PMID: 21751047.
      View in: PubMed
    52. Lake JE, Wohl D, Scherzer R, Grunfeld C, Tien PC, Sidney S, Currier JS. Regional fat deposition and cardiovascular risk in HIV infection: the FRAM study. AIDS Care. 2011 Aug; 23(8):929-38. PMID: 21767228; PMCID: PMC3249238.
    53. Jotwani V, Scherzer R, Choi A, Szczech L, Polak JF, Kronmal RA, Grunfeld C, Shlipak M. Reduced kidney function and preclinical atherosclerosis in HIV-infected individuals: the study of fat redistribution and metabolic change in HIV infection (FRAM). Am J Nephrol. 2011; 33(5):453-60. PMID: 21508633; PMCID: PMC3100378.
    54. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation inhibits the expression of phosphoenolpyruvate carboxykinase in liver and adipose tissue. Innate Immun. 2012 Apr; 18(2):231-40. PMID: 21450790.
      View in: PubMed
    55. Rooney T, Scherzer R, Shigenaga JK, Graf J, Imboden JB, Grunfeld C. Levels of plasma fibrinogen are elevated in well-controlled rheumatoid arthritis. Rheumatology (Oxford). 2011 Aug; 50(8):1458-65. PMID: 21441551.
      View in: PubMed
    56. Yarasheski KE, Scherzer R, Kotler DP, Dobs AS, Tien PC, Lewis CE, Kronmal RA, Heymsfield SB, Bacchetti P, Grunfeld C. Age-related skeletal muscle decline is similar in HIV-infected and uninfected individuals. J Gerontol A Biol Sci Med Sci. 2011 Mar; 66(3):332-40. PMID: 21310810; PMCID: PMC3041474.
    57. Shlipak MG, Li Y, Fox C, Coresh J, Grunfeld C, Whooley M. Uromodulin concentrations are not associated with incident CKD among persons with coronary artery disease. BMC Nephrol. 2011 Jan 14; 12:2. PMID: 21235779; PMCID: PMC3031204.
    58. Crane HM, Grunfeld C, Willig JH, Mugavero MJ, Van Rompaey S, Moore R, Rodriguez B, Feldman BJ, Lederman MM, Saag MS, Kitahata MM. Impact of NRTIs on lipid levels among a large HIV-infected cohort initiating antiretroviral therapy in clinical care. AIDS. 2011 Jan 14; 25(2):185-95. PMID: 21150555.
      View in: PubMed
    59. Tien PC, Choi AI, Zolopa AR, Benson C, Tracy R, Scherzer R, Bacchetti P, Shlipak M, Grunfeld C. Inflammation and mortality in HIV-infected adults: analysis of the FRAM study cohort. J Acquir Immune Defic Syndr. 2010 Nov; 55(3):316-22. PMID: 20581689; PMCID: PMC2955817.
    60. Taylor SA, Lee GA, Pao VY, Anthonypillai J, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers. J Acquir Immune Defic Syndr. 2010 Nov; 55(3):361-4. PMID: 20595906; PMCID: PMC3164483.
    61. Feingold KR, Grunfeld C. The role of HDL in innate immunity. J Lipid Res. 2011 Jan; 52(1):1-3. PMID: 20944062; PMCID: PMC2999920.
    62. Delaney JA, Scherzer R, Biggs ML, Shliplak MG, Polak JF, Currier JS, Kronmal RA, Wanke C, Bacchetti P, O'leary D, Tien PC, Grunfeld C. Associations of antiretroviral drug use and HIV-specific risk factors with carotid intima-media thickness. AIDS. 2010 Sep 10; 24(14):2201-9. PMID: 20671544; PMCID: PMC3224487.
    63. Lu B, Jiang YJ, Kim P, Moser A, Elias PM, Grunfeld C, Feingold KR. Expression and regulation of GPAT isoforms in cultured human keratinocytes and rodent epidermis. J Lipid Res. 2010 Nov; 51(11):3207-16. PMID: 20719759; PMCID: PMC2952561.
    64. Choi A, Scherzer R, Bacchetti P, Tien PC, Saag MS, Gibert CL, Szczech LA, Grunfeld C, Shlipak MG. Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons. Am J Kidney Dis. 2010 Nov; 56(5):872-82. PMID: 20709438; PMCID: PMC3164880.
    65. Grunfeld C. Dyslipidemia and its Treatment in HIV Infection. Top HIV Med. 2010 Aug-Sep; 18(3):112-8. PMID: 20921577; PMCID: PMC3189481.
    66. Grunfeld C, Saag M, Cofrancesco J, Lewis CE, Kronmal R, Heymsfield S, Tien PC, Bacchetti P, Shlipak M, Scherzer R. Regional adipose tissue measured by MRI over 5 years in HIV-infected and control participants indicates persistence of HIV-associated lipoatrophy. AIDS. 2010 Jul 17; 24(11):1717-26. PMID: 20502316; PMCID: PMC3309711.
    67. Rao MN, Mulligan K, Tai V, Wen MJ, Dyachenko A, Weinberg M, Li X, Lang T, Grunfeld C, Schwarz JM, Schambelan M. Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance. J Clin Endocrinol Metab. 2010 Sep; 95(9):4361-6. PMID: 20610601; PMCID: PMC2936071.
    68. Scherzer R, Shen W, Heymsfield SB, Lewis CE, Kotler DP, Punyanitya M, Bacchetti P, Shlipak MG, Grunfeld C. Intermuscular adipose tissue and metabolic associations in HIV infection. Obesity (Silver Spring). 2011 Feb; 19(2):283-91. PMID: 20539305; PMCID: PMC3731045.
    69. Delaney JA, Scherzer R, Polak J, Biggs ML, Kronmal R, Chen H, Sidney S, Grunfeld C. Effect of inter-reader variability on outcomes in studies using carotid intima media thickness quantified by carotid ultrasonography. Eur J Epidemiol. 2010 Jun; 25(6):385-92. PMID: 20309612; PMCID: PMC3161119.
    70. Shrestha S, Irvin MR, Taylor KD, Wiener HW, Pajewski NM, Haritunians T, Delaney JA, Schambelan M, Polak JF, Arnett DK, Chen YD, Grunfeld C. A genome-wide association study of carotid atherosclerosis in HIV-infected men. AIDS. 2010 Feb 20; 24(4):583-92. PMID: 20009918; PMCID: PMC3072760.
    71. Feingold KR, Shigenaga JK, Patzek SM, Chui LG, Moser A, Grunfeld C. Endotoxin, zymosan, and cytokines decrease the expression of the transcription factor, carbohydrate response element binding protein, and its target genes. Innate Immun. 2011 Apr; 17(2):174-82. PMID: 20100709.
      View in: PubMed
    72. Choi AI, Li Y, Deeks SG, Grunfeld C, Volberding PA, Shlipak MG. Association between kidney function and albuminuria with cardiovascular events in HIV-infected persons. Circulation. 2010 Feb 09; 121(5):651-8. PMID: 20100969; PMCID: PMC2829672.
    73. Grunfeld C, Scherzer R, Varosy PD, Ambarish G, Nasir K, Budoff M. Relation of coronary artery plaque location to extent of coronary artery disease studied by computed tomographic angiography. J Cardiovasc Comput Tomogr. 2010 Jan-Feb; 4(1):19-26. PMID: 20159623.
      View in: PubMed
    74. Pao VY, Lee GA, Taylor S, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers. AIDS. 2010 Jan 16; 24(2):265-70. PMID: 19890203.
      View in: PubMed
    75. Feingold KR, Grunfeld C. The acute phase response inhibits reverse cholesterol transport. J Lipid Res. 2010 Apr; 51(4):682-4. PMID: 20071695; PMCID: PMC2842157.
    76. Cockerham L, Scherzer R, Zolopa A, Rimland D, Lewis CE, Bacchetti P, Grunfeld C, Shlipak M, Tien PC. Association of HIV infection, demographic and cardiovascular risk factors with all-cause mortality in the recent HAART era. J Acquir Immune Defic Syndr. 2010 Jan; 53(1):102-6. PMID: 19738484; PMCID: PMC2799541.
    77. Lu B, Moser A, Shigenaga JK, Grunfeld C, Feingold KR. The acute phase response stimulates the expression of angiopoietin like protein 4. Biochem Biophys Res Commun. 2010 Jan 22; 391(4):1737-41. PMID: 20043872.
      View in: PubMed
    78. Lee GA, Schwarz JM, Patzek S, Kim S, Dyachenko A, Wen M, Mulligan K, Schambelan M, Grunfeld C. The acute effects of HIV protease inhibitors on insulin suppression of glucose production in healthy HIV-negative men. J Acquir Immune Defic Syndr. 2009 Oct 01; 52(2):246-8. PMID: 19680131; PMCID: PMC3164488.
    79. Grunfeld C, Delaney JA, Wanke C, Currier JS, Scherzer R, Biggs ML, Tien PC, Shlipak MG, Sidney S, Polak JF, O'Leary D, Bacchetti P, Kronmal RA. Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study. AIDS. 2009 Sep 10; 23(14):1841-9. PMID: 19455012; PMCID: PMC3156613.
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    153. Monto A, Alonzo J, Watson JJ, Grunfeld C, Wright TL. Steatosis in chronic hepatitis C: relative contributions of obesity, diabetes mellitus, and alcohol. Hepatology. 2002 Sep; 36(3):729-36. PMID: 12198667.
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