Patricia Defechereux, PhD

SchoolUCSF School of Medicine
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    1. Kerrigan D, Mantsios A, Grant R, Markowitz M, Defechereux P, La Mar M, Beckham SW, Hammond P, Margolis D, Murray M. Expanding the Menu of HIV Prevention Options: A Qualitative Study of Experiences with Long-Acting Injectable Cabotegravir as PrEP in the Context of a Phase II Trial in the United States. AIDS Behav. 2017 Dec 30. PMID: 29290075.
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    2. Mehrotra ML, Glidden DV, McMahan V, Amico KR, Hosek S, Defechereux P, Mayer KH, Veloso VG, Bekker LG, Avelino-Silva VI, Schechter M, Grant RM. The Effect of Depressive Symptoms on Adherence to Daily Oral PrEP in Men who have Sex with Men and Transgender Women: A Marginal Structural Model Analysis of The iPrEx OLE Study. AIDS Behav. 2016 Jul; 20(7):1527-34. PMID: 27125241.
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    3. Defechereux P, Mehrotra M, Liu AY, McMahan VM, Glidden DV, Mayer KH, Vargas L, Amico KR, Chodacki P, Fernandez T, Avelino-Silva VI, Burns D, Grant RM. Depression and Oral FTC/TDF Pre-exposure Prophylaxis (PrEP) Among Men and Transgender Women Who Have Sex With Men (MSM/TGW). AIDS Behav. 2016 Jul; 20(7):1478-88. PMID: 26078115.
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    4. Kuebler PJ, Mehrotra ML, Shaw BI, Leadabrand KS, Milush JM, York VA, Defechereux P, Grant RM, Kallás EG, Nixon DF. Persistent HIV Type 1 Seronegative Status Is Associated With Lower CD8+ T-Cell Activation. J Infect Dis. 2016 Feb 15; 213(4):569-73. PMID: 26310308; PMCID: PMC4721903 [Available on 02/15/17].
    5. Gandhi M, Glidden DV, Liu A, Anderson PL, Horng H, Defechereux P, Guanira JV, Grinsztejn B, Chariyalertsak S, Bekker LG, Grant RM. Strong Correlation Between Concentrations of Tenofovir (TFV) Emtricitabine (FTC) in Hair and TFV Diphosphate and FTC Triphosphate in Dried Blood Spots in the iPrEx Open Label Extension: Implications for Pre-exposure Prophylaxis Adherence Monitoring. J Infect Dis. 2015 Nov 01; 212(9):1402-6. PMID: 25895984; PMCID: PMC4601920 [Available on 11/01/16].
    6. Grant RM, Liegler T, Defechereux P, Kashuba AD, Taylor D, Abdel-Mohsen M, Deese J, Fransen K, De Baetselier I, Crucitti T, Bentley G, Agingu W, Ahmed K, Damme LV. Drug resistance and plasma viral RNA level after ineffective use of oral pre-exposure prophylaxis in women. AIDS. 2015 Jan 28; 29(3):331-7. PMID: 25503265.
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    7. Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, Goicochea P, Casapía M, Guanira-Carranza JV, Ramirez-Cardich ME, Montoya-Herrera O, Fernández T, Veloso VG, Buchbinder SP, Chariyalertsak S, Schechter M, Bekker LG, Mayer KH, Kallás EG, Amico KR, Mulligan K, Bushman LR, Hance RJ, Ganoza C, Defechereux P, Postle B, Wang F, McConnell JJ, Zheng JH, Lee J, Rooney JF, Jaffe HS, Martinez AI, Burns DN, Glidden DV. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010 Dec 30; 363(27):2587-99. PMID: 21091279; PMCID: PMC3079639.
    8. Weinberg A, Song LY, Walker R, Allende M, Fenton T, Patterson-Bartlett J, Nachman S, Kemble G, Yi TT, Defechereux P, Wara D, Read JS, Levin M. Anti-influenza serum and mucosal antibody responses after administration of live attenuated or inactivated influenza vaccines to HIV-infected children. J Acquir Immune Defic Syndr. 2010 Oct; 55(2):189-96. PMID: 20581690; PMCID: PMC3290334.
    9. Weinberg A, Song LY, Wilkening C, Sevin A, Blais B, Louzao R, Stein D, Defechereux P, Durand D, Riedel E, Raftery N, Jesser R, Brown B, Keller MF, Dickover R, McFarland E, Fenton T. Optimization and limitations of use of cryopreserved peripheral blood mononuclear cells for functional and phenotypic T-cell characterization. Clin Vaccine Immunol. 2009 Aug; 16(8):1176-86. PMID: 19515870; PMCID: PMC2725535.
    10. Weinberg A, Gona P, Nachman SA, Defechereux P, Yogev R, Hughes W, Wara D, Spector SA, Read J, Elgie C, Cooper M, Dankner W. Antibody responses to hepatitis A virus vaccine in HIV-infected children with evidence of immunologic reconstitution while receiving highly active antiretroviral therapy. J Infect Dis. 2006 Jan 15; 193(2):302-11. PMID: 16362896.
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    11. Jordan A, Defechereux P, Verdin E. The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J. 2001 Apr 02; 20(7):1726-38. PMID: 11285236; PMCID: PMC145503.
    12. Baudoux L, Defechereux P, Rentier B, Piette J. Gene activation by Varicella-zoster virus IE4 protein requires its dimerization and involves both the arginine-rich sequence, the central part, and the carboxyl-terminal cysteine-rich region. J Biol Chem. 2000 Oct 20; 275(42):32822-31. PMID: 10889190.
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    13. Sadzot-Delvaux C, Baudoux L, Defechereux P, Piette J, Rentier B. Overview of the replication cycle of varicella-zoster virus. Contrib Microbiol. 1999; 3:21-42. PMID: 10599519.
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    14. Defechereux P, Debrus S, Baudoux L, Rentier B, Piette J. Varicella-zoster virus open reading frame 4 encodes an immediate-early protein with posttranscriptional regulatory properties. J Virol. 1997 Sep; 71(9):7073-9. PMID: 9261438; PMCID: PMC191997.
    15. Rentier B, Piette J, Baudoux L, Debrus S, Defechereux P, Merville MP, Sadzot-Delvaux C, Schoonbroodt S. Lessons to be learned from varicella-zoster virus. Vet Microbiol. 1996 Nov; 53(1-2):55-66. PMID: 9010998.
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    16. Schoonbroodt S, Piette J, Baudoux L, Defechereux P, Rentier B, Merville MP. Enhancement of varicella-zoster virus infection in cell lines expressing ORF4- or ORF62-encoded proteins. J Med Virol. 1996 Aug; 49(4):264-73. PMID: 8877757.
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    17. Defechereux P, Debrus S, Baudoux L, Schoonbroodt S, Merville MP, Rentier B, Piette J. Intracellular distribution of the ORF4 gene product of varicella-zoster virus is influenced by the IE62 protein. J Gen Virol. 1996 Jul; 77 ( Pt 7):1505-13. PMID: 8757993.
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    18. Piette J, Defechereux P, Baudoux L, Debrus S, Merville MP, Rentier B. Varicella-zoster virus gene regulation. Neurology. 1995 Dec; 45(12 Suppl 8):S23-7. PMID: 8545012.
      View in: PubMed
    19. Baudoux L, Defechereux P, Schoonbroodt S, Merville MP, Rentier B, Piette J. Mutational analysis of varicella-zoster virus major immediate-early protein IE62. Nucleic Acids Res. 1995 Apr 25; 23(8):1341-9. PMID: 7753624; PMCID: PMC306859.
    20. Kinchington PR, Vergnes JP, Defechereux P, Piette J, Turse SE. Transcriptional mapping of the varicella-zoster virus regulatory genes encoding open reading frames 4 and 63. J Virol. 1994 Jun; 68(6):3570-81. PMID: 8189496; PMCID: PMC236861.
    21. Defechereux P, Melen L, Baudoux L, Merville-Louis MP, Rentier B, Piette J. Characterization of the regulatory functions of varicella-zoster virus open reading frame 4 gene product. J Virol. 1993 Jul; 67(7):4379-85. PMID: 8389935; PMCID: PMC237810.
    22. Jackers P, Defechereux P, Baudoux L, Lambert C, Massaer M, Merville-Louis MP, Rentier B, Piette J. Characterization of regulatory functions of the varicella-zoster virus gene 63-encoded protein. J Virol. 1992 Jun; 66(6):3899-903. PMID: 1316489; PMCID: PMC241178.
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