Yumi Fukuzaki, PhD

Title(s)Associate Specialist, Neurology
SchoolSchool of Medicine
Address675 Nelson Rising Lane, #494
San Francisco CA 94158
Phone415-502-7285
PronounsShe/Her/Hers
ORCID ORCID Icon0000-0001-8870-4210 Additional info
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    Collapse Biography 
    Collapse education and training
    University of Oxford, Oxford, UKPostdoc12/2019Cerebral cortical development
    Gunma University, Gunma, JapanPostdoc11/2018Neurophysiology and Neural Repair
    Soka University, Tokyo, JapanPostdoc10/2017Neuroscience
    Soka University, Tokyo, JapanPhD9/2015Bioscience, Cell biology
    RIKEN Brain Science Institute (BSI), Saitama, Japan6/2013Brain Science Training Program
    RIKEN Center for Developmental Biology (CDB), Kobe, JAPAN3/2013iPS culture training course
    Collapse awards and honors
    2012  - 2012Best Poster Award, Congress of Asia Pacific Association of Laser Medicine & Surgery 2012, Taipei, TA
    2013  - 2013Best Lecture Award, Laser Florence 2013, Florence, ITALY
    Soka Univiersity2012  - 2012DaVinci Award (Outstanding performance award)
    JP Student Services Organization2014  - 2014Repayment Exemption for Students with Excellent Grades

    Collapse Overview 
    Collapse overview
    I am a developmental neuroscience researcher currently working as an Associate Specialist in the Department of Neurology at the University of California, San Francisco (UCSF). My research focuses on the role of microglia and extracellular vesicles (EVs) in neonatal brain injury, particularly ischemic stroke. I aim to uncover novel mechanisms of neuroinflammation and to develop targeted RNA-based therapies that promote brain repair during early life.

    I earned my PhD in Bioscience from Soka University in 2015, followed by postdoctoral research at Gunma University and the University of Oxford. I later joined UCSF as a postdoctoral scholar and, in 2022, transitioned to my current role as an Associate Specialist under the mentorship of Professor Zena Vexler. My current work integrates molecular biology, immunology, and developmental neuroscience, utilizing techniques such as flow cytometry, EV profiling, and AAV-mediated gene delivery in neonatal mouse models. I am driven by a strong interest in improving long-term neurological outcomes in infants affected by perinatal brain disorders.

    Collapse Research 
    Collapse research activities and funding
    Post doctoral Fellowship from the Uehara Memorial Foundation Nov 1, 2018 - Nov 1, 2019
    Kato Memorial Bioscience Foundation Subsidy for International Exchange May 1, 2017 - May 30, 2017
    Research Fellowship for Young Scientists DC2-PD from Japan Society for the Promotion of Science (JSPS) Apr 1, 2014 - Mar 31, 2016
    The Naito Foundation Subsidy for Dispatch of Young Researchers Abroad Nov 1, 2013 - Dec 1, 2013
    Sasakawa Scientific Research Grant from The Japan Science Society Apr 1, 2011 - Mar 31, 2012

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Global sphingosine-1-phosphate receptor 2 deficiency attenuates neuroinflammation and ischemic-reperfusion injury after neonatal stroke. iScience. 2023 Apr 21; 26(4):106340. Fukuzaki Y, Faustino J, Lecuyer M, Rayasam A, Vexler ZS. PMID: 37009213; PMCID: PMC10064246.
      View in: PubMed   Mentions: 1  
    2. Microglia-leucocyte axis in cerebral ischaemia and inflammation in the developing brain. Acta Physiol (Oxf). 2021 09; 233(1):e13674. Rayasam A, Fukuzaki Y, Vexler ZS. PMID: 33991400; PMCID: PMC9093042.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    3. Pharmacological enhancement of retinoid-related orphan receptor α function mitigates spinocerebellar ataxia type 3 pathology. Neurobiol Dis. 2019 01; 121:263-273. Watanave M, Hoshino C, Konno A, Fukuzaki Y, Matsuzaki Y, Ishitani T, Hirai H. PMID: 30343032.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    4. 532 nm Low-Power Laser Irradiation Facilitates the Migration of GABAergic Neural Stem/Progenitor Cells in Mouse Neocortex. PLoS One. 2014; 10(4):e0123833. Fukuzaki Y, Shin H, Kawai HD, Yamanoha B, Kogure S. PMID: 25919297; PMCID: PMC4412395.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    5. 532 nm low-power laser irradiation recovers γ-secretase inhibitor-mediated cell growth suppression and promotes cell proliferation via Akt signaling. PLoS One. 2013; 8(8):e70737. Fukuzaki Y, Sugawara H, Yamanoha B, Kogure S. PMID: 23950991; PMCID: PMC3737144.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    6. Immunocytochemical studies on the effect of 405-nm low-power laser irradiation on human-derived A-172 glioblastoma cells. Lasers Med Sci. 2012 Sep; 27(5):935-42. Ang FY, Fukuzaki Y, Yamanoha B, Kogure S. PMID: 22041845.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
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