Chao Tang • UCSF Profiles

Chao Tang, PhD

Title(s)	Professor, Bioengineering
School	School of Pharmacy
Address	Location Required, #001 Varies CA 00000
Phone	415-514-4414
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Biography

Awards and Honors

University of Chicago	1982 -	1982	Valentine Telegdi Prize, University of Chicago
American Physical Society	1997 -	1997	Fellow, the American Physical Society
OverseaNational Science Foundation of China	2002 -	2002	Overseas Chinese Young Scholars Award, National Science Foundation of China
Troisième	2003 -	2003	Troisième Cycle Lecture, Lausanne, Switzerland
Chinese Ministry of Education	2003 -	2003	Chang Jiang Scholar Award, Chinese Ministry of Education
Chinese University of Hong Kong	2006 -	2006	Croucher Lecture, Chinese University of Hong Kong
	2011 -	2011	China Thousand Talent Program

Overview

We are a Systems Biology lab. We are interested in quantitative studies of biological systems, applying and developing quantitative methods and tools to address key biological questions. We believe that an interdisciplinary approach focusing on quantitative questions at a systems level will uncover new biological principles and help us to better understand complex disease and design new therapeutic strategies. The lab has both wet and dry components. Some of our current projects include: yeast cell cycle regulation, stress response, the function and topology of biological networks, modeling cancer pathways and development, systems drug design, and theoretical issues in systems biology.

Websites

Profile at limlab.ucsf.edu

Research

Research Activities and Funding

Quantitative studies of cell cycle checkpoints and switches
NIH R01GM097115Aug 8, 2011 - May 31, 2015
Role: Principal Investigator

Exploring Design Principles of Cellular Control Circuits
NIH P50GM081879Sep 1, 2010 - Jul 31, 2019
Role: Co-Investigator

ORNG Applications

Academic Senate

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Defining network topologies that can achieve biochemical adaptation. Cell. 2009 Aug 21; 138(4):760-73. Ma W, Trusina A, El-Samad H, Lim WA, Tang C. PMID: 19703401; PMCID: PMC3068210.

View in: PubMed Mentions: 376 Fields:
Cel Cell Biology
Translation:Cells
Rationalizing translation attenuation in the network architecture of the unfolded protein response. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20280-5. Trusina A, Papa FR, Tang C. PMID: 19075238; PMCID: PMC2603256.

View in: PubMed Mentions: 24 Fields:
Sci Science
Translation:Animals Cells
Finding multiple target optimal intervention in disease-related molecular network. Mol Syst Biol. 2008; 4:228. Yang K, Bai H, Ouyang Q, Lai L, Tang C. PMID: 18985027; PMCID: PMC2673713.

View in: PubMed Mentions: 69 Fields:
Com Computational Biology Mol Molecular Biology
Translation:Humans
Robust, tunable biological oscillations from interlinked positive and negative feedback loops. Science. 2008 Jul 04; 321(5885):126-9. Tsai TY, Choi YS, Ma W, Pomerening JR, Tang C, Ferrell JE. PMID: 18599789; PMCID: PMC2728800.

View in: PubMed Mentions: 272 Fields:
Sci Science
Translation:Animals
SCUMBLE: a method for systematic and accurate detection of codon usage bias by maximum likelihood estimation. Nucleic Acids Res. 2008 Jun; 36(11):3819-27. Kloster M, Tang C. PMID: 18495752; PMCID: PMC2441815.

View in: PubMed Mentions: 9 Fields:
Bio Biochemistry
Translation:Animals Cells
Function constrains network architecture and dynamics: a case study on the yeast cell cycle Boolean network. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 May; 75(5 Pt 1):051907. Lau KY, Ganguli S, Tang C. PMID: 17677098.

View in: PubMed Mentions: 21 Fields:
Bio Biophysics Phy Physics Phy Physiology Sta Statistics as Topic
Translation:Animals Cells
Robustness and modular design of the Drosophila segment polarity network. Mol Syst Biol. 2006; 2:70. Ma W, Lai L, Ouyang Q, Tang C. PMID: 17170765; PMCID: PMC1762089.

View in: PubMed Mentions: 66 Fields:
Com Computational Biology Mol Molecular Biology
Translation:Animals Cells
Dynamic studies of scaffold-dependent mating pathway in yeast. Biophys J. 2006 Dec 01; 91(11):3986-4001. Shao D, Zheng W, Qiu W, Ouyang Q, Tang C. PMID: 16980360; PMCID: PMC1635675.

View in: PubMed Mentions: 17 Fields:
Bio Biophysics
Translation:Animals Cells
Finding regulatory modules through large-scale gene-expression data analysis. Bioinformatics. 2005 Apr 01; 21(7):1172-9. Kloster M, Tang C, Wingreen NS. PMID: 15513996.

View in: PubMed Mentions: 13 Fields:
Com Computational Biology
Translation:Cells
The yeast cell-cycle network is robustly designed. Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):4781-6. Li F, Long T, Lu Y, Ouyang Q, Tang C. PMID: 15037758; PMCID: PMC387325.

View in: PubMed Mentions: 308 Fields:
Sci Science
Translation:Animals
Simulation and analysis of in vitro DNA evolution. Phys Rev Lett. 2004 Jan 23; 92(3):038101. Kloster M, Tang C. PMID: 14753913.

View in: PubMed Mentions: 1 Fields:
Med Medicine (General)
Translation:Cells