Peter Walter, PhD

Title(s)Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address35 Medical Center Way, #001
San Francisco CA 94143
Phone415-476-4636
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    Other Positions
    Title(s)Howard Hughes Investigator


    Collapse Biography 
    Collapse Awards and Honors
    Breakthrough Foundation2018Breakthrough Prize in Life Science
    Vilcek Foundation2015Vilcek Prize in Biomedical Science
    Lasker Foundation2014Lasker Basic Medical Research Award
    UCSF2014Shaw Prize in Life Science and Medicine
    UCSF2012Paul Ehrlich and Ludwig Darmstaedter Prize

    Collapse Overview 
    Collapse Overview
    Our laboratory seeks a molecular understanding of how cells control the quality of their proteins and organelles during homeostasis and stress. We are identifying the machinery and mechanisms that ensure proper protein synthesis, folding, and targeting, as well as the pathways that allow organelles to communicate and regulate their abundance. Additionally, we aim to understand how the rewiring of these processes leads to, or prevents the progression of disease. Our laboratory uses a diverse array of techniques, ranging from biochemical reconstitution to genetics, to fuel our search for fundamental discoveries in cell biology.
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    Collapse Research 
    Collapse Research Activities and Funding
    Structural Basis of Protein Homeostasis
    NIH U01GM098254Sep 30, 2012 - Jul 31, 2016
    Role: Principal Investigator
    The integrated stress response in cognitive disorders
    NIH R01NS076708Mar 15, 2012 - Mar 31, 2026
    Role: Co-Principal Investigator
    Stress Proteins in Growth, Development &Disease 2007Gordon Research Conference
    NIH R13AG030760Jun 1, 2007 - May 31, 2008
    Role: Principal Investigator
    Membrane Protein Expression Center
    NIH P50GM073210Sep 24, 2004 - Aug 31, 2015
    Role: Co-Investigator
    QUATTRO ALLIANCE FOR SCIENCE AND LANGUAGE INTEGRATION
    NIH R25RR018504Sep 30, 2003 - Aug 31, 2007
    Role: Co-Principal Investigator
    Molecular Cell Biology Gordon Conference
    NIH R13CA091820Jul 1, 2001 - Jun 30, 2002
    Role: Principal Investigator
    Comprehensive Biology: Exploiting the Yeast Genome
    NIH P41RR011823Sep 30, 1996 - Jun 30, 2016
    Role: Co-Investigator
    PROTEIN TRANSLOCATION IN YEAST
    NIH R01GM037485Dec 1, 1986 - Nov 30, 1999
    Role: Principal Investigator
    Co-translational ER quality control
    NIH R01GM032384Jul 1, 1983 - Apr 30, 2024
    Role: Principal Investigator
    MECHANISM OF PROTEIN TRANSLOCATION ACROSS MEMBRANES
    NIH R37GM032384Jul 1, 1983 - Jun 30, 2003
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Homeostasis control in health and disease by the unfolded protein response. Nat Rev Mol Cell Biol. 2024 Nov 05. Acosta-Alvear D, Harnoss JM, Walter P, Ashkenazi A. PMID: 39501044.
      View in: PubMed   Mentions:    Fields:    
    2. Selective bioorthogonal probe for N-glycan hybrid structures. Nat Chem Biol. 2024 Oct 28. Mukherjee MM, Biesbrock D, Abramowitz LK, Pavan M, Kumar B, Walter PJ, Azadi P, Jacobson KA, Hanover JA. PMID: 39468349.
      View in: PubMed   Mentions:    Fields:    
    3. Correction: eIF2B conformation and assembly state regulate the integrated stress response. Elife. 2024 Oct 03; 13. Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P. PMID: 39361021; PMCID: PMC11449477.
      View in: PubMed   Mentions:    Fields:    
    4. A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat Chem Biol. 2024 Apr; 20(4):422-431. Lawrence RE, Shoemaker SR, Deal A, Sangwan S, Anand AA, Wang L, Marqusee S, Walter P. PMID: 37945896; PMCID: PMC10972756.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    5. A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response. Nat Cell Biol. 2023 Nov; 25(11):1600-1615. Subramanian A, Wang L, Moss T, Voorhies M, Sangwan S, Stevenson E, Pulido EH, Kwok S, Chalkley RJ, Li KH, Krogan NJ, Swaney DL, Burlingame AL, Floor SN, Sil A, Walter P, Mukherjee S. PMID: 37857833; PMCID: PMC11005034.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    6. Early Alterations of RNA Binding Protein (RBP) Homeostasis and ER Stress-Mediated Autophagy Contributes to Progressive Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa (RP). Cells. 2023 04 06; 12(7). Yamoah A, Tripathi P, Guo H, Scheve L, Walter P, Johnen S, Müller F, Weis J, Goswami A. PMID: 37048167; PMCID: PMC10092976.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    7. A central helical switch controls integrated stress response signaling via eIF2B conformation and assembly. Biophysical Journal. 2023 Feb 1; 122(3):32a. Lawrence LR, Shoemaker SS, Deal DA, Wang WL, Marqusee MS, Walter WP. .
      View in: Publisher Site   Mentions:
    8. Observation of site-selective chemical bond changes via ultrafast chemical shifts. Nat Commun. 2022 11 22; 13(1):7170. Al-Haddad A, Oberli S, González-Vázquez J, Bucher M, Doumy G, Ho P, Krzywinski J, Lane TJ, Lutman A, Marinelli A, Maxwell TJ, Moeller S, Pratt ST, Ray D, Shepard R, Southworth SH, Vázquez-Mayagoitia Á, Walter P, Young L, Picón A, Bostedt C. PMID: 36418902; PMCID: PMC9684563.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    9. Aberrant cortical spine dynamics after concussive injury are reversed by integrated stress response inhibition. Proc Natl Acad Sci U S A. 2022 10 18; 119(42):e2209427119. Frias ES, Hoseini MS, Krukowski K, Paladini MS, Grue K, Ureta G, Rienecker KDA, Walter P, Stryker MP, Rosi S. PMID: 36227915; PMCID: PMC9586300.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    10. Endoplasmic reticulum stress activates human IRE1α through reversible assembly of inactive dimers into small oligomers. Elife. 2022 06 22; 11. Belyy V, Zuazo-Gaztelu I, Alamban A, Ashkenazi A, Walter P. PMID: 35730415; PMCID: PMC9217129.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    11. Conserved structural elements specialize ATAD1 as a membrane protein extraction machine. Elife. 2022 05 12; 11. Wang L, Toutkoushian H, Belyy V, Kokontis CY, Walter P. PMID: 35550246; PMCID: PMC9273213.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    12. Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii. Nat Genet. 2022 05; 54(5):705-714. Fauser F, Vilarrasa-Blasi J, Onishi M, Ramundo S, Patena W, Millican M, Osaki J, Philp C, Nemeth M, Salomé PA, Li X, Wakao S, Kim RG, Kaye Y, Grossman AR, Niyogi KK, Merchant SS, Cutler SR, Walter P, Dinneny JR, Jonikas MC, Jinkerson RE. PMID: 35513725; PMCID: PMC9110296.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    13. A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation. Elife. 2022 04 13; 11. Boone M, Wang L, Lawrence RE, Frost A, Walter P, Schoof M. PMID: 35416150; PMCID: PMC9132573.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    14. Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression. EMBO Mol Med. 2022 04 07; 14(4):e15344. Yildirim Z, Baboo S, Hamid SM, Dogan AE, Tufanli O, Robichaud S, Emerton C, Diedrich JK, Vatandaslar H, Nikolos F, Gu Y, Iwawaki T, Tarling E, Ouimet M, Nelson DL, Yates JR, Walter P, Erbay E. PMID: 35191199; PMCID: PMC8988208.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    15. Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α. Nat Commun. 2021 12 15; 12(1):7310. Le Thomas A, Ferri E, Marsters S, Harnoss JM, Lawrence DA, Zuazo-Gaztelu I, Modrusan Z, Chan S, Solon M, Chalouni C, Li W, Koeppen H, Rudolph J, Wang W, Wu TD, Walter P, Ashkenazi A. PMID: 34911951; PMCID: PMC8674358.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    16. Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B. Nat Commun. 2021 12 07; 12(1):7103. Schoof M, Wang L, Cogan JZ, Lawrence RE, Boone M, Wuerth JD, Frost A, Walter P. PMID: 34876554; PMCID: PMC8651678.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    17. BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J. 2021 Nov 02; 40(21):e109149. Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C. PMID: 34726286; PMCID: PMC8561629.
      View in: PubMed   Mentions:    Fields:    
    18. Small molecule cognitive enhancer reverses age-related memory decline in mice. Brain Behavior and Immunity. 2021 Nov 1; 98:27. Krukowski KK, Nolan NA, Frias FE, Boone BM, Ureta UG, Grue GK, Paladini PM, Elizarraras EE, Delgado DL, Bernales BS, Walter WP, Rosi RS. .
      View in: Publisher Site   Mentions:
    19. The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes. Science. 2021 Oct; 374(6563):52-57. Tran NH, Carter SD, De Mazière A, Ashkenazi A, Klumperman J, Walter P, Jensen GJ. PMID: 34591618; PMCID: PMC9041316.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    20. Cristae-dependent quality control of the mitochondrial genome. Sci Adv. 2021 Sep 03; 7(36):eabi8886. Jakubke C, Roussou R, Maiser A, Schug C, Thoma F, Bunk D, Hörl D, Leonhardt H, Walter P, Klecker T, Osman C. PMID: 34516914; PMCID: PMC8442932.
      View in: PubMed   Mentions: 17     Fields:    
    21. Moderate levels of 5-fluorocytosine cause the emergence of high frequency resistance in cryptococci. Nat Commun. 2021 06 08; 12(1):3418. Chang YC, Lamichhane AK, Cai H, Walter PJ, Bennett JE, Kwon-Chung KJ. PMID: 34103502; PMCID: PMC8187385.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    22. eIF2B Conformation and Assembly State Regulate the Integrated Stress Response. The FASEB Journal. 2021 May 14; 35(S1). Schoof SM, Boone BM, Wang WL, Lawrence LR, Frost FA, Walter WP. .
      View in: Publisher Site   Mentions:
    23. Protomer alignment modulates specificity of RNA substrate recognition by Ire1. Elife. 2021 04 27; 10. Li W, Crotty K, Garrido Ruiz D, Voorhies M, Rivera C, Sil A, Mullins RD, Jacobson MP, Peschek J, Walter P. PMID: 33904404; PMCID: PMC8104961.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    24. Correction: Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response. J Cell Biol. 2021 04 05; 220(4). Schuck S, Prinz WA, Thorn KS, Voss C, Walter P. PMID: 33600553; PMCID: PMC7888336.
      View in: PubMed   Mentions: 3     Fields:    
    25. eIF2B conformation and assembly state regulate the integrated stress response. Elife. 2021 03 10; 10. Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P. PMID: 33688831; PMCID: PMC7990499.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    26. Coexpressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts. Proc Natl Acad Sci U S A. 2020 12 22; 117(51):32739-32749. Ramundo S, Asakura Y, Salomé PA, Strenkert D, Boone M, Mackinder LCM, Takafuji K, Dinc E, Rahire M, Crèvecoeur M, Magneschi L, Schaad O, Hippler M, Jonikas MC, Merchant S, Nakai M, Rochaix JD, Walter P. PMID: 33273113; PMCID: PMC7768757.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    27. Small molecule cognitive enhancer reverses age-related memory decline in mice. Elife. 2020 12 01; 9. Krukowski K, Nolan A, Frias ES, Boone M, Ureta G, Grue K, Paladini MS, Elizarraras E, Delgado L, Bernales S, Walter P, Rosi S. PMID: 33258451; PMCID: PMC7721440.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    28. An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science. 2020 12 18; 370(6523):1473-1479. Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. PMID: 33154106; PMCID: PMC7857409.
      View in: PubMed   Mentions: 224     Fields:    Translation:HumansAnimalsCells
    29. Blockade of Retinal Oscillations by Benzodiazepines Improves Efficiency of Electrical Stimulation in the Mouse Model of RP, rd10. Invest Ophthalmol Vis Sci. 2020 11 02; 61(13):37. Gehlen J, Esser S, Schaffrath K, Johnen S, Walter P, Müller F. PMID: 33252632; PMCID: PMC7705397.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    30. Msp1/ATAD1 in Protein Quality Control and Regulation of Synaptic Activities. Annu Rev Cell Dev Biol. 2020 10 06; 36:141-164. Wang L, Walter P. PMID: 32886535.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    31. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation. bioRxiv. 2020 Aug 17. Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. PMID: 32817938; PMCID: PMC7430568.
      View in: PubMed   Mentions: 6  
    32. Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association. Nat Microbiol. 2020 11; 5(11):1361-1373. Rabouw HH, Visser LJ, Passchier TC, Langereis MA, Liu F, Giansanti P, van Vliet ALW, Dekker JG, van der Grein SG, Saucedo JG, Anand AA, Trellet ME, Bonvin AMJJ, Walter P, Heck AJR, de Groot RJ, van Kuppeveld FJM. PMID: 32690955.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    33. Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response. Nat Commun. 2020 05 14; 11(1):2401. Dufey E, Bravo-San Pedro JM, Eggers C, González-Quiroz M, Urra H, Sagredo AI, Sepulveda D, Pihán P, Carreras-Sureda A, Hazari Y, Sagredo EA, Gutierrez D, Valls C, Papaioannou A, Acosta-Alvear D, Campos G, Domingos PM, Pedeux R, Chevet E, Alvarez A, Godoy P, Walter P, Glavic A, Kroemer G, Hetz C. PMID: 32409639; PMCID: PMC7224204.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    34. The integrated stress response: From mechanism to disease. Science. 2020 04 24; 368(6489). Costa-Mattioli M, Walter P. PMID: 32327570; PMCID: PMC8997189.
      View in: PubMed   Mentions: 510     Fields:    Translation:HumansAnimalsCells
    35. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment. Cancer Res. 2020 06 01; 80(11):2368-2379. Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A. PMID: 32265225; PMCID: PMC7272310.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    36. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Sci Adv. 2020 04; 6(14):eaay9572. Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z. PMID: 32270040; PMCID: PMC7112762.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    37. Regulating ER protein homeostasis by differentially processing mRNAs. The FASEB Journal. 2020 Apr 1; 34(S1):1-1. Li LW, Crotty CK, Ruiz RD, Peschek PJ, Walter WP. .
      View in: Publisher Site   Mentions:
    38. Integrated Stress Response Inhibitor Reverses Sex-Dependent Behavioral and Cell-Specific Deficits after Mild Repetitive Head Trauma. J Neurotrauma. 2020 06 01; 37(11):1370-1380. Krukowski K, Nolan A, Frias ES, Grue K, Becker M, Ureta G, Delgado L, Bernales S, Sohal VS, Walter P, Rosi S. PMID: 31884883; PMCID: PMC7249463.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    39. Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. Elife. 2020 01 30; 9. Wang L, Myasnikov A, Pan X, Walter P. PMID: 31999255; PMCID: PMC7018516.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    40. The role of transient resonances for ultra-fast imaging of single sucrose nanoclusters. Nat Commun. 2020 01 09; 11(1):167. Ho PJ, Daurer BJ, Hantke MF, Bielecki J, Al Haddad A, Bucher M, Doumy G, Ferguson KR, Flückiger L, Gorkhover T, Iwan B, Knight C, Moeller S, Osipov T, Ray D, Southworth SH, Svenda M, Timneanu N, Ulmer A, Walter P, Hajdu J, Young L, Maia FRNC, Bostedt C. PMID: 31919346; PMCID: PMC6952381.
      View in: PubMed   Mentions: 8     Fields:    
    41. Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress. Elife. 2020 01 06; 9. Lam M, Marsters SA, Ashkenazi A, Walter P. PMID: 31904339; PMCID: PMC7041945.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    42. Quantitative microscopy reveals dynamics and fate of clustered IRE1α. Proc Natl Acad Sci U S A. 2020 01 21; 117(3):1533-1542. Belyy V, Tran NH, Walter P. PMID: 31871156; PMCID: PMC6983381.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    43. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science. 2019 11 15; 366(6467):843-849. Zhu PJ, Khatiwada S, Cui Y, Reineke LC, Dooling SW, Kim JJ, Li W, Walter P, Costa-Mattioli M. PMID: 31727829; PMCID: PMC7299149.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    44. Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response. FEBS J. 2020 01; 287(2):239-245. Anand AA, Walter P. PMID: 31550413.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    45. The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. Elife. 2019 10 15; 8. Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S. PMID: 31612858; PMCID: PMC6794094.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    46. Mrx6 regulates mitochondrial DNA copy number in Saccharomyces cerevisiae by engaging the evolutionarily conserved Lon protease Pim1. Mol Biol Cell. 2020 03 19; 31(7):527-545. Göke A, Schrott S, Mizrak A, Belyy V, Osman C, Walter P. PMID: 31532710; PMCID: PMC7202074.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    47. From symbiont to parasite: the evolution of for-profit science publishing. Mol Biol Cell. 2019 09 15; 30(20):2537-2542. Walter P, Mullins D. PMID: 31539315; PMCID: PMC6740196.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum. Cold Spring Harb Perspect Biol. 2019 09 03; 11(9). Karagöz GE, Acosta-Alvear D, Walter P. PMID: 30670466; PMCID: PMC6719602.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansAnimalsCells
    49. A Novel Role of Fungal Type I Myosin in Regulating Membrane Properties and Its Association with d-Amino Acid Utilization in Cryptococcus gattii. mBio. 2019 08 27; 10(4). Khanal Lamichhane A, Garraffo HM, Cai H, Walter PJ, Kwon-Chung KJ, Chang YC. PMID: 31455652; PMCID: PMC6712397.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    50. Withdrawal: Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum. J Biol Chem. 2019 Aug 09; 294(32):12263. Doolittle MH, Neher SB, Ben-Zeev O, Ling-Liao J, Gallagher CM, Hosseini M, Yin F, Wong H, Walter P, Péterfy M. PMID: 31399538; PMCID: PMC6690689.
      View in: PubMed   Mentions:    Fields:    
    51. Disruption of IRE1α through its kinase domain attenuates multiple myeloma. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16420-16429. Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen YA, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun MG, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A. PMID: 31371506; PMCID: PMC6697881.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    52. In vitro RNA Cleavage Assays to Characterize IRE1-dependent RNA Decay. Bio Protoc. 2019 Jul 20; 9(14):e3307. Karagöz GE, Peschek J, Walter P, Acosta-Alvear D. PMID: 33654817; PMCID: PMC7854161.
      View in: PubMed   Mentions: 1  
    53. tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay. Elife. 2019 06 25; 8. Peschek J, Walter P. PMID: 31237564; PMCID: PMC6592678.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    54. Pulmonary Iron Limitation Induced by Exogenous Type I IFN Protects Mice from Cryptococcus gattii Independently of T Cells. mBio. 2019 06 18; 10(3). Davis MJ, Moyer S, Hoke ES, Sionov E, Mayer-Barber KD, Barber DL, Cai H, Jenkins L, Walter PJ, Chang YC, Kwon-Chung KJ. PMID: 31213551; PMCID: PMC6581853.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    55. Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. Elife. 2019 05 31; 8. Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. PMID: 31149896; PMCID: PMC6588346.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    56. Electrospray sample injection for single-particle imaging with x-ray lasers. Sci Adv. 2019 05; 5(5):eaav8801. Bielecki J, Hantke MF, Daurer BJ, Reddy HKN, Hasse D, Larsson DSD, Gunn LH, Svenda M, Munke A, Sellberg JA, Flueckiger L, Pietrini A, Nettelblad C, Lundholm I, Carlsson G, Okamoto K, Timneanu N, Westphal D, Kulyk O, Higashiura A, van der Schot G, Loh ND, Wysong TE, Bostedt C, Gorkhover T, Iwan B, Seibert MM, Osipov T, Walter P, Hart P, Bucher M, Ulmer A, Ray D, Carini G, Ferguson KR, Andersson I, Andreasson J, Hajdu J, Maia FRNC. PMID: 31058226; PMCID: PMC6499549.
      View in: PubMed   Mentions: 23     Fields:    
    57. eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Science. 2019 05 03; 364(6439):491-495. Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A. PMID: 31048491; PMCID: PMC6601628.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    58. Abstract # 2056 Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury. Brain Behavior and Immunity. 2019 Feb 1; 76:e5. Krukowski KK, Chou CA, Jopson JT, Zhu ZP, Costa-Mattioli CM, Walter WP, Rosi RS. .
      View in: Publisher Site   Mentions:
    59. Small molecule ISRIB suppresses the integrated stress response within a defined window of activation. Proc Natl Acad Sci U S A. 2019 02 05; 116(6):2097-2102. Rabouw HH, Langereis MA, Anand AA, Visser LJ, de Groot RJ, Walter P, van Kuppeveld FJM. PMID: 30674674; PMCID: PMC6369741.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    60. The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1. Elife. 2018 12 24; 7. Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P. PMID: 30582518; PMCID: PMC6336407.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    61. Confirming a critical role for death receptor 5 and caspase-8 in apoptosis induction by endoplasmic reticulum stress. Cell Death Differ. 2018 08; 25(8):1530-1531. Lam M, Lawrence DA, Ashkenazi A, Walter P. PMID: 29991746; PMCID: PMC6113221.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    62. Engineering ER-stress dependent non-conventional mRNA splicing. Elife. 2018 07 09; 7. Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P. PMID: 29985129; PMCID: PMC6037481.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    63. Leonardo Gallery: Scientific Delirium Madness 4.0. Leonardo. 2018 Jun 1; 51(03):227-238. Knight KM, Nardelli NM, Davidson DA, Eklund EK, Hawthorne HK, LaCerva LG, LeBoeuf LA, Le Gal LP, Ramirez RA, Spence SH, Tejerina-Risso TJ, Walter WP. .
      View in: Publisher Site   Mentions:
    64. Development of a stress response therapy targeting aggressive prostate cancer. Sci Transl Med. 2018 05 02; 10(439). Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D. PMID: 29720449; PMCID: PMC6045425.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    65. Günter Blobel (1936-2018). Science. 2018 Apr 27; 360(6387):383. Walter P, Anderson D. PMID: 29700255.
      View in: PubMed   Mentions:    Fields:    
    66. Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. Cell Host Microbe. 2018 04 11; 23(4):571. Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. PMID: 29649448; PMCID: PMC5916756.
      View in: PubMed   Mentions: 2     Fields:    
    67. Regulating ER Protein Folding Homeostasis By Distinctively Processing mRNAs. The FASEB Journal. 2018 Apr 1; 32:653.9-653.9. Li LW, Okreglak OV, Peschek PJ, Kimmig KP, Walter WP. .
      View in: Publisher Site   Mentions:
    68. Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Science. 2018 03 30; 359(6383). Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P. PMID: 29599213; PMCID: PMC6120582.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    69. An unfolded protein-induced conformational switch activates mammalian IRE1. Elife. 2017 10 03; 6. Karagöz GE, Acosta-Alvear D, Nguyen HT, Lee CP, Chu F, Walter P. PMID: 28971800; PMCID: PMC5699868.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    70. Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe. Elife. 2017 09 25; 6. Guydosh NR, Kimmig P, Walter P, Green R. PMID: 28945192; PMCID: PMC5650469.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    71. Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling. J Cell Sci. 2017 Oct 01; 130(19):3222-3233. Cohen N, Breker M, Bakunts A, Pesek K, Chas A, Argemí J, Orsi A, Gal L, Chuartzman S, Wigelman Y, Jonas F, Walter P, Ernst R, Aragón T, van Anken E, Schuldiner M. PMID: 28794014; PMCID: PMC5665437.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    72. Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):E6420-E6426. Chou A, Krukowski K, Jopson T, Zhu PJ, Costa-Mattioli M, Walter P, Rosi S. PMID: 28696288; PMCID: PMC5547647.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    73. BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J. 2017 06 01; 36(11):1640. Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C. PMID: 28572284; PMCID: PMC5452024.
      View in: PubMed   Mentions: 2     Fields:    
    74. Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proc Natl Acad Sci U S A. 2017 02 21; 114(8):E1395-E1404. Tufanli O, Telkoparan Akillilar P, Acosta-Alvear D, Kocaturk B, Onat UI, Hamid SM, Çimen I, Walter P, Weber C, Erbay E. PMID: 28137856; PMCID: PMC5338400.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    75. eIF2α-mediated translational control regulates the persistence of cocaine-induced LTP in midbrain dopamine neurons. Elife. 2016 12 13; 5. Placzek AN, Prisco GV, Khatiwada S, Sgritta M, Huang W, Krnjevic K, Kaufman RJ, Dani JA, Walter P, Costa-Mattioli M. PMID: 27960077; PMCID: PMC5154759.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    76. Multiple selection filters ensure accurate tail-anchored membrane protein targeting. Elife. 2016 12 07; 5. Rao M, Okreglak V, Chio US, Cho H, Walter P, Shan SO. PMID: 27925580; PMCID: PMC5214336.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    77. CD46 Is Amplified in High-Risk Myeloma with Gain of Chromosome 1q and Selectively Targeted By a Novel Anti-CD46 Antibody-Drug Conjugate. Blood. 2016 Dec 2; 128(22):384-384. Sherbenou SD, Aftab AB, Su SY, Behrens BC, Wiita WA, Logan LA, Acosta-Alvear AD, Hann HB, Walter WP, Wu WX, Atkinson AJ, Wolf WJ, Martin MT, Liu LB. .
      View in: Publisher Site   Mentions:
    78. Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells. J Clin Invest. 2016 12 01; 126(12):4640-4653. Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B. PMID: 27841764; PMCID: PMC5127683.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    79. Science as a Way of Knowing: From Protein Machines to Evidence-Based Decisions. Cell. 2016 Sep 22; 167(1):16-19. Walter P, Yamamoto KR. PMID: 27634318.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    80. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 08 09; 113(32):9015-20. Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. PMID: 27450084; PMCID: PMC4987817.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    81. Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. Elife. 2016 07 20; 5. Plate L, Cooley CB, Chen JJ, Paxman RJ, Gallagher CM, Madoux F, Genereux JC, Dobbs W, Garza D, Spicer TP, Scampavia L, Brown SJ, Rosen H, Powers ET, Walter P, Hodder P, Wiseman RL, Kelly JW. PMID: 27435961; PMCID: PMC4954754.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCells
    82. Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress. Elife. 2016 07 20; 5. Gallagher CM, Walter P. PMID: 27435962; PMCID: PMC4954756.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    83. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. Elife. 2016 07 20; 5. Gallagher CM, Garri C, Cain EL, Ang KK, Wilson CG, Chen S, Hearn BR, Jaishankar P, Aranda-Diaz A, Arkin MR, Renslo AR, Walter P. PMID: 27435960; PMCID: PMC4954757.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansCells
    84. Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods. Curr Eye Res. 2017 02; 42(2):273-281. Rösch S, Aretzweiler C, Müller F, Walter P. PMID: 27362633.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    85. Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine. Elife. 2016 Mar 01; 5. Huang W, Placzek AN, Viana Di Prisco G, Khatiwada S, Sidrauski C, Krnjevic K, Walter P, Dani JA, Costa-Mattioli M. PMID: 26928234; PMCID: PMC4786430.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    86. Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2α. Elife. 2016 Mar 01; 5. Placzek AN, Molfese DL, Khatiwada S, Viana Di Prisco G, Huang W, Sidrauski C, Krnjevic K, Amos CL, Ray R, Dani JA, Walter P, Salas R, Costa-Mattioli M. PMID: 26928076; PMCID: PMC4786418.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    87. Translation from the 5' untranslated region shapes the integrated stress response. Science. 2016 Jan 29; 351(6272):aad3867. Starck SR, Tsai JC, Chen K, Shodiya M, Wang L, Yahiro K, Martins-Green M, Shastri N, Walter P. PMID: 26823435; PMCID: PMC4882168.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansCells
    88. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19; 11(8):870-80. Hearn BR, Jaishankar P, Sidrauski C, Tsai JC, Vedantham P, Fontaine SD, Walter P, Renslo AR. PMID: 26789650.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    89. Abstract A2-12: Opposing roles of the 19S regulatory and 20S core proteasomal subunits in controlling sensitivity to proteasome inhibitors. Genomics and Target Discovery. 2015 Nov 15; a2-12-a2-12. Cho CM, Acosta-Alvear AD, Kampmann KM, Wild WT, Choudhary CC, Weissman WJ, Walter WP. .
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    90. Abstract A2-56: Cancer-specific synthetic lethality and network rewiring elucidated by genetic interaction maps and CRISPR-based gain- and loss-of-function screens. Network-Based Cancer Biology. 2015 Nov 15; a2-56-a2-56. Kampmann KM, Acosta-Alvear AD, Gilbert GL, Horlbeck HM, Cho CM, Adamson AB, Villalta VJ, Chen CY, Walter WP, Weissman WJ. .
      View in: Publisher Site   Mentions:
    91. Abstract A2-57: Identification of genetic vulnerabilities within the proteostasis network of multiple myeloma. Network-Based Cancer Biology. 2015 Nov 15; a2-57-a2-57. Acosta-Alvear AD, Kampmann KM, Cho CM, Aftab AB, Li LX, Gestwicki GJ, Shuman SM, Weissman WJ, Walter WP. .
      View in: Publisher Site   Mentions:
    92. Dynamics of co-translational protein targeting. Curr Opin Chem Biol. 2015 Dec; 29:79-86. Elvekrog MM, Walter P. PMID: 26517565; PMCID: PMC4684440.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    93. A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing. EMBO Rep. 2015 Dec; 16(12):1688-98. Peschek J, Acosta-Alvear D, Mendez AS, Walter P. PMID: 26483401; PMCID: PMC4687415.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    94. ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13. J Cell Biol. 2015 Sep 14; 210(6):883-90. Lang AB, John Peter AT, Walter P, Kornmann B. PMID: 26370498; PMCID: PMC4576869.
      View in: PubMed   Mentions: 126     Fields:    Translation:AnimalsCells
    95. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 2015 Sep 01; 4:e08153. Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. PMID: 26327694; PMCID: PMC4602331.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    96. Abstract A43: Opposing roles of the 19S regulatory- and 20S core-proteasomal subunits in controlling sensitivity of multiple myeloma cells to proteasome inhibition. Myeloma. 2015 Sep 1; a43-a43. Acosta-Alvear AD, Kampmann KM, Cho CM, Wild WT, Choudhary CC, Shuman SM, Weissman WJ, Walter WP. .
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    97. Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic. Elife. 2015 May 19; 4. Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P. PMID: 25986605; PMCID: PMC4436593.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    98. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 2015 Apr 15; 4:e07314. Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. PMID: 25875391; PMCID: PMC4426669.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansCells
    99. The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly. Elife. 2015 Feb 26; 4. Sidrauski C, McGeachy AM, Ingolia NT, Walter P. PMID: 25719440; PMCID: PMC4341466.
      View in: PubMed   Mentions: 295     Fields:    Translation:AnimalsCells
    100. Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):E947-56. Osman C, Noriega TR, Okreglak V, Fung JC, Walter P. PMID: 25730886; PMCID: PMC4352819.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    101. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer. Mol Cancer Ther. 2015 Mar; 14(3):642-8. Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. PMID: 25564440; PMCID: PMC4456214.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    102. Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1. Elife. 2014 Dec 30; 3:e05031. van Anken E, Pincus D, Coyle S, Aragón T, Osman C, Lari F, Gómez Puerta S, Korennykh AV, Walter P. PMID: 25549299; PMCID: PMC4279078.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    103. Real-time observation of signal recognition particle binding to actively translating ribosomes. Elife. 2014 Oct 30; 3. Noriega TR, Chen J, Walter P, Puglisi JD. PMID: 25358118; PMCID: PMC4213662.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    104. Lasker Award winner Peter Walter. Nat Med. 2014 Oct; 20(10):1112-4. Walter P. PMID: 25295946.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    105. Delayed Ras/PKA signaling augments the unfolded protein response. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14800-5. Pincus D, Aranda-Díaz A, Zuleta IA, Walter P, El-Samad H. PMID: 25275008; PMCID: PMC4205644.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    106. ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery. J Cell Sci. 2014 Sep 15; 127(Pt 18):4078-88. Schuck S, Gallagher CM, Walter P. PMID: 25052096; PMCID: PMC4163648.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCells
    107. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science. 2014 Jul 04; 345(6192):98-101. Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A. PMID: 24994655; PMCID: PMC4284148.
      View in: PubMed   Mentions: 306     Fields:    Translation:HumansAnimalsCells
    108. Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α. Nat Neurosci. 2014 Aug; 17(8):1073-82. Di Prisco GV, Huang W, Buffington SA, Hsu CC, Bonnen PE, Placzek AN, Sidrauski C, Krnjevic K, Kaufman RJ, Walter P, Costa-Mattioli M. PMID: 24974795; PMCID: PMC4340591.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    109. The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8019-24. Okreglak V, Walter P. PMID: 24821790; PMCID: PMC4050615.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    110. Signal recognition particle-ribosome binding is sensitive to nascent chain length. J Biol Chem. 2014 Jul 11; 289(28):19294-305. Noriega TR, Tsai A, Elvekrog MM, Petrov A, Neher SB, Chen J, Bradshaw N, Puglisi JD, Walter P. PMID: 24808175; PMCID: PMC4094042.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    111. Molecular mechanisms of hypoxic responses via unique roles of Ras1, Cdc24 and Ptp3 in a human fungal pathogen Cryptococcus neoformans. PLoS Genet. 2014 Apr; 10(4):e1004292. Chang YC, Khanal Lamichhane A, Garraffo HM, Walter PJ, Leerkes M, Kwon-Chung KJ. PMID: 24762475; PMCID: PMC3998916.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    112. Identification of key components involved in mtDNA inheritance during cell division (965.1). The FASEB Journal. 2014 Apr 1; 28. Camacho CB, Osman OC, Walter WP. .
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    113. Heat shock transcription factor σ32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli. PLoS Biol. 2013 Dec; 11(12):e1001735. Lim B, Miyazaki R, Neher S, Siegele DA, Ito K, Walter P, Akiyama Y, Yura T, Gross CA. PMID: 24358019; PMCID: PMC3866087.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    114. Abstract C01: Systematic blueprinting of genetic vulnerabilities using ultra-complex shRNA libraries identifies genes synergizing with proteasome inhibition or blockade of IRE1 in multiple myeloma cells. Signaling and Drug Resistance. 2013 Oct 1; c01-c01. Acosta-Alvear AD, Kampmann KM, Bassik BM, Lee LC, Cho CM, Aftab AB, Li LX, Gestwicki GJ, Shuman SM, Weissman WJ, Walter WP. .
      View in: Publisher Site   Mentions:
    115. Abstract PR07: Systematic genetic interaction maps reveal rewiring of the stress response network and resulting vulnerabilities in leukemia and multiple myeloma cells. Interpreting the Cancer Genome. 2013 Oct 1; pr07-pr07. Kampmann KM, Acosta-Alvear AD, Cho CM, Chen CY, Li LX, Gilbert GL, Aftab AB, Gestwicki GJ, Walter WP, Weissman WJ. .
      View in: Publisher Site   Mentions:
    116. Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife. 2013 May 28; 2:e00498. Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. PMID: 23741617; PMCID: PMC3667625.
      View in: PubMed   Mentions: 360     Fields:    Translation:HumansAnimalsCells
    117. The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host Microbe. 2013 May 15; 13(5):558-569. Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. PMID: 23684307; PMCID: PMC3766372.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    118. ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. Elife. 2013 May 14; 2:e00422. Murley A, Lackner LL, Osman C, West M, Voeltz GK, Walter P, Nunnari J. PMID: 23682313; PMCID: PMC3654481.
      View in: PubMed   Mentions: 168     Fields:    Translation:AnimalsCells
    119. Abstract PR06: Systematic genetic interaction maps reveal synthetic-lethal vulnerabilities in leukemia and multiple myeloma. Systemic Functional Genomics. 2013 May 1; pr06-pr06. Kampmann KM, Acosta-Alvear AD, Bassik BM, Chen CY, Walter WP, Weissman WJ. .
      View in: Publisher Site   Mentions:
    120. Abstract A08: Systematic identification of genetic vulnerabilities synergizing with proteasome and IRE1 inhibition in multiple myeloma cells using ultra-complex shRNA libraries. Genome Scale Synthetic Lethal Screens in Model Organisms. 2013 May 1; a08-a08. Acosta-Alvear AD, Kampmann KM, Bassik BM, Lee LC, Shuman SM, Weissman WJ, Walter WP. .
      View in: Publisher Site   Mentions:
    121. Two structure papers, a call from Frankfurt airport, and how to escape from reviewer delays: an interview with Peter Walter by Miranda Robertson. BMC Biol. 2013 Apr 15; 11:34. Walter P. PMID: 23587131; PMCID: PMC3626913.
      View in: PubMed   Mentions:    Fields:    
    122. Predicting where small molecules bind at protein-protein interfaces. PLoS One. 2013; 8(3):e58583. Walter P, Metzger J, Thiel C, Helms V. PMID: 23505538; PMCID: PMC3591369.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    123. Endoplasmic reticulum stress sensing in the unfolded protein response. Cold Spring Harb Perspect Biol. 2013 Mar 01; 5(3):a013169. Gardner BM, Pincus D, Gotthardt K, Gallagher CM, Walter P. PMID: 23388626; PMCID: PMC3578356.
      View in: PubMed   Mentions: 379     Fields:    Translation:HumansAnimalsCells
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    297. Binding sites of the 9- and 14-kilodalton heterodimeric protein subunit of the signal recognition particle (SRP) are contained exclusively in the Alu domain of SRP RNA and contain a sequence motif that is conserved in evolution. Mol Cell Biol. 1991 Aug; 11(8):3949-59. Strub K, Moss J, Walter P. PMID: 1712900; PMCID: PMC361190.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    298. Binding sites of the 9- and 14-kilodalton heterodimeric protein subunit of the signal recognition particle (SRP) are contained exclusively in the Alu domain of SRP RNA and contain a sequence motif that is conserved in evolution. Molecular and Cellular Biology. 1991 Aug 1; 11(8):3949-3959. Strub SK, Moss MJ, Walter WP. .
      View in: Publisher Site   Mentions:
    299. Binding Sites of the 9- and 14-Kilodalton Heterodimeric Protein Subunit of the Signal Recognition Particle (SRP) Are Contained Exclusively in the Alu Domain of SRP RNA and Contain a Sequence Motif That Is Conserved in Evolution. Molecular and Cellular Biology. 1991 Aug 1; 11(8):3949-3959. Strub SK, Moss MJ, Walter WP. .
      View in: Publisher Site   Mentions:
    300. Small ribonucleoproteins. Current Opinion in Structural Biology. 1991 Apr 1; 1(2):251-257. Wolin WS, Walter WP. .
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    301. Response: "Sequence-Gazing?". Science. 1991 Mar 8; 251(4998):1161-1162. Poritz PM, Bernstein BH, Walter WP. .
      View in: Publisher Site   Mentions:
    302. Response: "Sequence-Gazing?". Science. 1991 Mar 8; 251(4998):1161-1162. Poritz PM, Bernstein BH, Walter WP. .
      View in: Publisher Site   Mentions:
    303. A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation. J Cell Biol. 1991 Mar; 112(5):809-21. Thrift RN, Andrews DW, Walter P, Johnson AE. PMID: 1999459; PMCID: PMC2288876.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    304. The methionine-rich domain of the 54 kd protein subunit of the signal recognition particle contains an RNA binding site and can be crosslinked to a signal sequence. EMBO J. 1990 Dec; 9(13):4511-7. Zopf D, Bernstein HD, Johnson AE, Walter P. PMID: 1702385; PMCID: PMC552245.
      View in: PubMed   Mentions: 82     Fields:    Translation:Cells
    305. An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science. 1990 Nov 23; 250(4984):1111-7. Poritz MA, Bernstein HD, Strub K, Zopf D, Wilhelm H, Walter P. PMID: 1701272.
      View in: PubMed   Mentions: 116     Fields:    Translation:Cells
    306. Yeast methionyl-tRNA synthetase: analysis of the N-terminal extension and the putative tRNA anticodon binding region by site-directed mutagenesis. Biochimie. 1990 Aug; 72(8):537-44. Walter P, Despons L, Laforet M, Ebel JP, Fasiolo F. PMID: 2126459.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    307. Reconstitution of protein translocation activity from partially solubilized microsomal vesicles. J Biol Chem. 1990 Mar 05; 265(7):4048-53. Zimmerman DL, Walter P. PMID: 2105958.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    308. Assembly of the Alu domain of the signal recognition particle (SRP): dimerization of the two protein components is required for efficient binding to SRP RNA. Mol Cell Biol. 1990 Feb; 10(2):777-84. Strub K, Walter P. PMID: 2153922; PMCID: PMC360878.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    309. Assembly of the Alu Domain of the Signal Recognition Particle (SRP): Dimerization of the Two Protein Components Is Required for Efficient Binding to SRP RNA. Molecular and Cellular Biology. 1990 Feb 1; 10(2):777-784. Strub SK, Walter WP. .
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    310. Assembly of the Alu domain of the signal recognition particle (SRP): dimerization of the two protein components is required for efficient binding to SRP RNA. Molecular and Cellular Biology. 1990 Feb 1; 10(2):777-784. Strub SK, Walter WP. .
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    311. Isolation of a cDNA clone of the 14-kDa subunit of the signal recognition particle by cross-hybridization of differently primed polymerase chain reactions. Proc Natl Acad Sci U S A. 1989 Dec; 86(24):9747-51. Strub K, Walter P. PMID: 2557625; PMCID: PMC298578.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    312. Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth. J Cell Biol. 1989 Dec; 109(6 Pt 2):3223-30. Hann BC, Poritz MA, Walter P. PMID: 2557350; PMCID: PMC2115968.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    313. Signal recognition particle mediates a transient elongation arrest of preprolactin in reticulocyte lysate. J Cell Biol. 1989 Dec; 109(6 Pt 1):2617-22. Wolin SL, Walter P. PMID: 2556403; PMCID: PMC2115964.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    314. Protein translocation across the endoplasmic reticulum membrane: identification by photocross-linking of a 39-kD integral membrane glycoprotein as part of a putative translocation tunnel. J Cell Biol. 1989 Nov; 109(5):2033-43. Krieg UC, Johnson AE, Walter P. PMID: 2808520; PMCID: PMC2115841.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    315. Deletion analysis in the amino-terminal extension of methionyl-tRNA synthetase from Saccharomyces cerevisiae shows that a small region is important for the activity and stability of the enzyme. J Biol Chem. 1989 Oct 15; 264(29):17126-30. Walter P, Weygand-Durasevic I, Sanni A, Ebel JP, Fasiolo F. PMID: 2677000.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    316. Cytosolic protein translocation factors. Is SRP still unique? Cell. 1989 Sep 22; 58(6):1017-9. Bernstein HD, Rapoport TA, Walter P. PMID: 2550141.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    317. Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle. Nature. 1989 Aug 10; 340(6233):482-6. Bernstein HD, Poritz MA, Strub K, Hoben PJ, Brenner S, Walter P. PMID: 2502718.
      View in: PubMed   Mentions: 159     Fields:    Translation:AnimalsCells
    318. Cassette mutagenic analysis of the yeast invertase signal peptide: effects on protein translocation. Mol Cell Biol. 1989 Aug; 9(8):3400-10. Ngsee JK, Hansen W, Walter P, Smith M. PMID: 2677671; PMCID: PMC362386.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    319. Assembly of proteins in the endoplasmic reticulum. Curr Opin Cell Biol. 1989 Aug; 1(4):635-8. Siegel V, Walter P. PMID: 2697275.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    320. Cassette Mutagenic Analysis of the Yeast Invertase Signal Peptide: Effects on Protein Translocation. Molecular and Cellular Biology. 1989 Aug 1; 9(8):3400-3410. Ngsee NJ, Hansen HW, Walter WP, Smith SM. .
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    321. Cassette mutagenic analysis of the yeast invertase signal peptide: effects on protein translocation. Molecular and Cellular Biology. 1989 Aug 1; 9(8):3400-3410. Ngsee NJ, Hansen HW, Walter WP, Smith SM. .
      View in: Publisher Site   Mentions:
    322. The Membranes of a Eukaryotic Cell1. Integrative and Comparative Biology. 1989 May 1; 29(2):501-510. WALTER WP. .
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    323. Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor. J Cell Biol. 1989 Mar; 108(3):797-810. Andrews DW, Lauffer L, Walter P, Lingappa VR. PMID: 2537835; PMCID: PMC2115407.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    324. The use of gene-fusions to determine membrane protein topology in Saccharomyces cerevisiae. J Cell Sci Suppl. 1989; 11:109-13. Green GN, Hansen W, Walter P. PMID: 2693456.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    325. Ribosome pausing and stacking during translation of a eukaryotic mRNA. EMBO J. 1988 Nov; 7(11):3559-69. Wolin SL, Walter P. PMID: 2850168; PMCID: PMC454858.
      View in: PubMed   Mentions: 235     Fields:    Translation:AnimalsCells
    326. Isolation and characterization of a cDNA clone encoding the 19 kDa protein of signal recognition particle (SRP): expression and binding to 7SL RNA. Nucleic Acids Res. 1988 Oct 25; 16(20):9431-42. Lingelbach K, Zwieb C, Webb JR, Marshallsay C, Hoben PJ, Walter P, Dobberstein B. PMID: 2460823; PMCID: PMC338754.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    327. Human SRP RNA and E. coli 4.5S RNA contain a highly homologous structural domain. Cell. 1988 Oct 07; 55(1):4-6. Poritz MA, Strub K, Walter P. PMID: 2458843.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    328. Functional dissection of the signal recognition particle. Trends Biochem Sci. 1988 Aug; 13(8):314-6. Siegel V, Walter P. PMID: 2856455.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    329. The affinity of signal recognition particle for presecretory proteins is dependent on nascent chain length. EMBO J. 1988 Jun; 7(6):1769-75. Siegel V, Walter P. PMID: 3169004; PMCID: PMC457167.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    330. Small ribonucleoproteins in Schizosaccharomyces pombe and Yarrowia lipolytica homologous to signal recognition particle. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4315-9. Poritz MA, Siegel V, Hansen W, Walter P. PMID: 2837764; PMCID: PMC280419.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    331. Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro. Nature. 1988 May 05; 333(6168):90-3. Kassenbrock CK, Garcia PD, Walter P, Kelly RB. PMID: 3129663.
      View in: PubMed   Mentions: 68     Fields:    Translation:Cells
    332. Prepro-carboxypeptidase Y and a truncated form of pre-invertase, but not full-length pre-invertase, can be posttranslationally translocated across microsomal vesicle membranes from Saccharomyces cerevisiae. J Cell Biol. 1988 Apr; 106(4):1075-81. Hansen W, Walter P. PMID: 3283144; PMCID: PMC2115026.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    333. Full-length prepro-alpha-factor can be translocated across the mammalian microsomal membrane only if translation has not terminated. J Cell Biol. 1988 Apr; 106(4):1043-8. Garcia PD, Walter P. PMID: 2834400; PMCID: PMC2115022.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    334. Targeting of the hepatitis B virus precore protein to the endoplasmic reticulum membrane: after signal peptide cleavage translocation can be aborted and the product released into the cytoplasm. J Cell Biol. 1988 Apr; 106(4):1093-104. Garcia PD, Ou JH, Rutter WJ, Walter P. PMID: 3283145; PMCID: PMC2114996.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    335. Binding sites of the 19-kDa and 68/72-kDa signal recognition particle (SRP) proteins on SRP RNA as determined in protein-RNA "footprinting". Proc Natl Acad Sci U S A. 1988 Mar; 85(6):1801-5. Siegel V, Walter P. PMID: 2450348; PMCID: PMC279867.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    336. Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: analysis of biochemical mutants of SRP. Cell. 1988 Jan 15; 52(1):39-49. Siegel V, Walter P. PMID: 2830980.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    337. Evidence for an extended 7SL RNA structure in the signal recognition particle. EMBO J. 1987 Nov; 6(11):3471-7. Andrews DW, Walter P, Ottensmeyer FP. PMID: 2828031; PMCID: PMC553805.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    338. Substrate requirements for SRP-mediated targeting to the ER membrane. Molecular Biology Reports. 1987 Sep 1; 12(3):219-219. Siegel SV, Garcia GP, Walter WP. .
      View in: Publisher Site   Mentions:
    339. Functional dissection of the signal recognition particle. Molecular Biology Reports. 1987 Sep 1; 12(3):220-220. Siegel SV, Poritz PM, Walter WP. .
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    340. Signal recognition. Two receptors act sequentially. Nature. 1987 Aug 27-Sep 2; 328(6133):763-4. Walter P. PMID: 3041220.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    341. Wild type and mutant signal peptides of Escherichia coli outer membrane lipoprotein interact with equal efficiency with mammalian signal recognition particle. J Biol Chem. 1987 Jul 15; 262(20):9463-8. Garcia PD, Ghrayeb J, Inouye M, Walter P. PMID: 3298258.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    342. Mathematical modeling of the effects of the signal recognition particle on translation and translocation of proteins across the endoplasmic reticulum membrane. J Mol Biol. 1987 Jun 05; 195(3):621-36. Rapoport TA, Heinrich R, Walter P, Schulmeister T. PMID: 2821280.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    343. Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle. Proc Natl Acad Sci U S A. 1986 Nov; 83(22):8604-8. Krieg UC, Walter P, Johnson AE. PMID: 3095839; PMCID: PMC386979.
      View in: PubMed   Mentions: 125     Fields:    Translation:Cells
    344. The signal recognition particle receptor is a complex that contains two distinct polypeptide chains. J Cell Biol. 1986 Oct; 103(4):1167-78. Tajima S, Lauffer L, Rath VL, Walter P. PMID: 3021779; PMCID: PMC2114348.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    345. In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factor. Cell. 1986 May 09; 45(3):397-406. Hansen W, Garcia PD, Walter P. PMID: 3009026.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    346. Removal of the Alu structural domain from signal recognition particle leaves its protein translocation activity intact. Nature. 1986 Mar 6-12; 320(6057):81-4. Siegel V, Walter P. PMID: 2419765.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    347. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature. 1986 Mar 13-19; 320(6058):134-9. Green S, Walter P, Kumar V, Krust A, Bornert JM, Argos P, Chambon P. PMID: 3754034.
      View in: PubMed   Mentions: 471     Fields:    Translation:HumansCells
    348. Mechanism of protein translocation across the endoplasmic reticulum membrane. Annu Rev Cell Biol. 1986; 2:499-516. Walter P, Lingappa VR. PMID: 3030381.
      View in: PubMed   Mentions: 165     Fields:    Translation:AnimalsCells
    349. The Protein Translocation Machinery of the Endoplasmic Reticulum: The Signal Hypothesis Ten Years Later. Protein Compartmentalization. 1986 Jan 1; 1-13. Walter WP, Siegel SV, Lauffer LL, Garcia GP. .
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    350. Intracellular Protein Topogenesis. New Insights into Cell and Membrane Transport Processes. 1986 Jan 1; 277-283. Blobel BG, Walter WP, Gilmore GR. .
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    351. Structure and Function of the Signal Recognition Particle. Genetic Engineering. 1986 Jan 1; 181-196. Siegel SV, Walter WP. .
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    352. Topology of signal recognition particle receptor in endoplasmic reticulum membrane. Nature. 1985 Nov 28-Dec 4; 318(6044):334-8. Lauffer L, Garcia PD, Harkins RN, Coussens L, Ullrich A, Walter P. PMID: 2999608.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    353. Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane. J Cell Biol. 1985 Jun; 100(6):1913-21. Siegel V, Walter P. PMID: 2581979; PMCID: PMC2113602.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    354. Structure of the signal recognition particle by electron microscopy. Proc Natl Acad Sci U S A. 1985 Feb; 82(3):785-9. Andrews DW, Walter P, Ottensmeyer FP. PMID: 3856232; PMCID: PMC397131.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    355. Protein translocation across the endoplasmic reticulum. Cell. 1984 Aug; 38(1):5-8. Walter P, Gilmore R, Blobel G. PMID: 6088076.
      View in: PubMed   Mentions: 216     Fields:    Translation:AnimalsCells
    356. Role of signal recognition particle in the membrane assembly of Sindbis viral glycoproteins. Eur J Biochem. 1984 May 02; 140(3):499-502. Bonatti S, Migliaccio G, Blobel G, Walter P. PMID: 6723645.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    357. Subcellular distribution of signal recognition particle and 7SL-RNA determined with polypeptide-specific antibodies and complementary DNA probe. J Cell Biol. 1983 Dec; 97(6):1693-9. Walter P, Blobel G. PMID: 6196367; PMCID: PMC2112735.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    358. Disassembly and reconstitution of signal recognition particle. Cell. 1983 Sep; 34(2):525-33. Walter P, Blobel G. PMID: 6413076.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    359. Translocation of a lysosomal enzyme across the microsomal membrane requires signal recognition particle. Biochem Biophys Res Commun. 1983 Aug 30; 115(1):275-80. Erickson AH, Walter P, Blobel G. PMID: 6137219.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    360. Signal recognition particle: a ribonucleoprotein required for cotranslational translocation of proteins, isolation and properties. Methods Enzymol. 1983; 96:682-91. Walter P, Blobel G. PMID: 6197610.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    361. The protein translocation machinery of the endoplasmic reticulum. Philos Trans R Soc Lond B Biol Sci. 1982 Dec 24; 300(1099):225-8. Walter P, Gilmore R, Müller M, Blobel G. PMID: 6131460.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    362. Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle. J Cell Biol. 1982 Nov; 95(2 Pt 1):463-9. Gilmore R, Blobel G, Walter P. PMID: 6292235; PMCID: PMC2112970.
      View in: PubMed   Mentions: 135     Fields:    Translation:Cells
    363. Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor. J Cell Biol. 1982 Nov; 95(2 Pt 1):470-7. Gilmore R, Walter P, Blobel G. PMID: 6292236; PMCID: PMC2112977.
      View in: PubMed   Mentions: 177     Fields:    Translation:Cells
    364. A bacterial secretory protein requires signal recognition particle for translocation across mammalian endoplasmic reticulum. J Biol Chem. 1982 Oct 25; 257(20):11860-3. Müller M, Ibrahimi I, Chang CN, Walter P, Blobel G. PMID: 6749848.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    365. Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum. Nature. 1982 Oct 21; 299(5885):691-8. Walter P, Blobel G. PMID: 6181418.
      View in: PubMed   Mentions: 268     Fields:    Translation:AnimalsCells
    366. Signal recognition protein is required for the integration of acetylcholine receptor delta subunit, a transmembrane glycoprotein, into the endoplasmic reticulum membrane. J Cell Biol. 1982 May; 93(2):501-6. Anderson DJ, Walter P, Blobel G. PMID: 7047541; PMCID: PMC2112847.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    367. Mechanism of protein translocation across the endoplasmic reticulum. Biochem Soc Symp. 1982; 47:183-91. Walter P, Blobel G. PMID: 6100822.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    368. THE PROTEIN TRANSLOCATION MACHINERY OF THE ENDOPLASMIC RETICULUM. Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression. 1982 Jan 1; 291-293. WALTER WP, GILMORE GR, MULLER MM, BLOBEL BG. .
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    369. Translocation of proteins across the endoplasmic reticulum. Oncodev Biol Med. 1982; 4(1-2):137-46. Walter P, Blobel G. PMID: 7177879.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    370. Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol. 1981 Nov; 91(2 Pt 1):551-6. Walter P, Blobel G. PMID: 7309796; PMCID: PMC2111991.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    371. Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes. J Cell Biol. 1981 Nov; 91(2 Pt 1):557-61. Walter P, Blobel G. PMID: 7309797; PMCID: PMC2111983.
      View in: PubMed   Mentions: 278     Fields:    Translation:AnimalsCells
    372. Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol. 1981 Nov; 91(2 Pt 1):545-50. Walter P, Ibrahimi I, Blobel G. PMID: 7309795; PMCID: PMC2111968.
      View in: PubMed   Mentions: 231     Fields:    Translation:AnimalsCells
    373. Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum. Proc Natl Acad Sci U S A. 1980 Dec; 77(12):7112-6. Walter P, Blobel G. PMID: 6938958; PMCID: PMC350451.
      View in: PubMed   Mentions: 200     Fields:    Translation:AnimalsCells
    374. Secretion requires a cytoplasmically disposed sulphydryl of the RER membrane. Nature. 1980 Jul 10; 286(5769):174-6. Jackson RC, Walter P, Blobel G. PMID: 6995850.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    375. Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol. 1979; 33:9-36. Blobel G, Walter P, Chang CN, Goldman BM, Erickson AH, Lingappa VR. PMID: 524275.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
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