Loading...

Peter Walter, PhD

Title(s)Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th St
San Francisco CA 94158
Phone415-476-4636
vCardDownload vCard
    Other Positions
    Title(s)Howard Hughes Investigator


    Collapse Biography 
    Collapse Awards and Honors
    Breakthrough Foundation2018Breakthrough Prize in Life Science
    Vilcek Foundation2015Vilcek Prize in Biomedical Science
    Lasker Foundation2014Lasker Basic Medical Research Award
    UCSF2014Shaw Prize in Life Science and Medicine
    UCSF2012Paul Ehrlich and Ludwig Darmstaedter Prize

    Collapse Overview 
    Collapse Overview
    Our laboratory seeks a molecular understanding of how cells control the quality of their proteins and organelles during homeostasis and stress. We are identifying the machinery and mechanisms that ensure proper protein synthesis, folding, and targeting, as well as the pathways that allow organelles to communicate and regulate their abundance. Additionally, we aim to understand how the rewiring of these processes leads to, or prevents the progression of disease. Our laboratory uses a diverse array of techniques, ranging from biochemical reconstitution to genetics, to fuel our search for fundamental discoveries in cell biology.

    Collapse Research 
    Collapse Research Activities and Funding
    Structural Basis of Protein Homeostasis
    NIH/NIGMS U01GM098254Sep 30, 2012 - Jul 31, 2015
    Role: Principal Investigator
    Stress Proteins in Growth, Development &Disease 2007Gordon Research Conference
    NIH/NIA R13AG030760Jun 1, 2007 - May 31, 2008
    Role: Principal Investigator
    Membrane Protein Expression Center
    NIH/NIGMS P50GM073210Sep 24, 2004 - Jul 31, 2009
    Role: Co-Investigator
    QUATTRO ALLIANCE FOR SCIENCE AND LANGUAGE INTEGRATION
    NIH/NCRR R25RR018504Sep 30, 2003 - Aug 31, 2007
    Role: Co-Principal Investigator
    Molecular Cell Biology Gordon Conference
    NIH/NCI R13CA091820Jul 1, 2001 - Jun 30, 2002
    Role: Principal Investigator
    Comprehensive Biology: Exploiting the Yeast Genome
    NIH P41RR011823Sep 30, 1996 - Jun 30, 2016
    Role: Co-Investigator
    PROTEIN TRANSLOCATION IN YEAST
    NIH/NIGMS R01GM037485Dec 1, 1986 - Nov 30, 1999
    Role: Principal Investigator
    Co-translational ER quality control
    NIH/NIGMS R01GM032384Jul 1, 1983 - Jun 30, 2007
    Role: Principal Investigator
    MECHANISM OF PROTEIN TRANSLOCATION ACROSS MEMBRANES
    NIH/NIGMS R37GM032384Jul 1, 1983 - Jun 30, 2003
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Msp1/ATAD1 in Protein Quality Control and Regulation of Synaptic Activities. Annu Rev Cell Dev Biol. 2020 Sep 04. Wang L, Walter P. PMID: 32886535.
      View in: PubMed   Mentions:    Fields:    
    2. An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation. bioRxiv. 2020 Aug 10. Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Zimanyi M, Deshpande I, Liang J, Anand AA, Dobzinski N, Zha BS, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Gupta S, Simoneau CR, Leon K, White KM, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, Walter P, Manglik A. PMID: 32817938.
      View in: PubMed   Mentions:
    3. Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association. Nat Microbiol. 2020 Jul 20. Rabouw HH, Visser LJ, Passchier TC, Langereis MA, Liu F, Giansanti P, van Vliet ALW, Dekker JG, van der Grein SG, Saucedo JG, Anand AA, Trellet ME, Bonvin AMJJ, Walter P, Heck AJR, de Groot RJ, van Kuppeveld FJM. PMID: 32690955.
      View in: PubMed   Mentions:    Fields:    
    4. Genotoxic stress triggers the activation of IRE1a-dependent RNA decay to modulate the DNA damage response. Nat Commun. 2020 05 14; 11(1):2401. Dufey E, Bravo-San Pedro JM, Eggers C, González-Quiroz M, Urra H, Sagredo AI, Sepulveda D, Pihán P, Carreras-Sureda A, Hazari Y, Sagredo EA, Gutierrez D, Valls C, Papaioannou A, Acosta-Alvear D, Campos G, Domingos PM, Pedeux R, Chevet E, Alvarez A, Godoy P, Walter P, Glavic A, Kroemer G, Hetz C. PMID: 32409639.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. The integrated stress response: From mechanism to disease. Science. 2020 04 24; 368(6489). Costa-Mattioli M, Walter P. PMID: 32327570.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. IRE1a Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment. Cancer Res. 2020 Jun 01; 80(11):2368-2379. Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A. PMID: 32265225.
      View in: PubMed   Mentions:    Fields:    
    7. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Sci Adv. 2020 04; 6(14):eaay9572. Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z. PMID: 32270040.
      View in: PubMed   Mentions:    Fields:    
    8. Regulating ER protein homeostasis by differentially processing mRNAs. The FASEB Journal. 2020 Apr 1; 34(S1):1-1. Weihan Li, Kelly Crotty, Diego Garrido Ruiz, Jirka Peschek, Peter Walter. .
      View in: Publisher Site   Mentions:
    9. Integrated Stress Response Inhibitor Reverses Sex-Dependent Behavioral and Cell-Specific Deficits after Mild Repetitive Head Trauma. J Neurotrauma. 2020 Jun 01; 37(11):1370-1380. Krukowski K, Nolan A, Frias ES, Grue K, Becker M, Ureta G, Delgado L, Bernales S, Sohal VS, Walter P, Rosi S. PMID: 31884883.
      View in: PubMed   Mentions:    Fields:    
    10. Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. Elife. 2020 Jan 30; 9. Wang L, Myasnikov A, Pan X, Walter P. PMID: 31999255.
      View in: PubMed   Mentions:    Fields:    
    11. Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress. Elife. 2020 Jan 06; 9. Lam M, Marsters SA, Ashkenazi A, Walter P. PMID: 31904339.
      View in: PubMed   Mentions: 4     Fields:    
    12. Quantitative microscopy reveals dynamics and fate of clustered IRE1a. Proc Natl Acad Sci U S A. 2020 01 21; 117(3):1533-1542. Belyy V, Tran NH, Walter P. PMID: 31871156.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    13. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science. 2019 11 15; 366(6467):843-849. Zhu PJ, Khatiwada S, Cui Y, Reineke LC, Dooling SW, Kim JJ, Li W, Walter P, Costa-Mattioli M. PMID: 31727829.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response. FEBS J. 2020 Jan; 287(2):239-245. Anand AA, Walter P. PMID: 31550413.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    15. The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. Elife. 2019 10 15; 8. Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S. PMID: 31612858.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    16. Mrx6 regulates mitochondrial DNA copy number in Saccharomyces cerevisiae by engaging the evolutionarily conserved Lon protease Pim1. Mol Biol Cell. 2020 03 19; 31(7):527-545. Göke A, Schrott S, Mizrak A, Belyy V, Osman C, Walter P. PMID: 31532710.
      View in: PubMed   Mentions: 1     Fields:    
    17. From symbiont to parasite: the evolution of for-profit science publishing. Mol Biol Cell. 2019 09 15; 30(20):2537-2542. Walter P, Mullins D. PMID: 31539315.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum. Cold Spring Harb Perspect Biol. 2019 09 03; 11(9). Karagöz GE, Acosta-Alvear D, Walter P. PMID: 30670466.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    19. A Novel Role of Fungal Type I Myosin in Regulating Membrane Properties and Its Association with d-Amino Acid Utilization in Cryptococcus gattii. mBio. 2019 08 27; 10(4). Khanal Lamichhane A, Garraffo HM, Cai H, Walter PJ, Kwon-Chung KJ, Chang YC. PMID: 31455652.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    20. Withdrawal: Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum. J Biol Chem. 2019 Aug 09; 294(32):12263. Doolittle MH, Neher SB, Ben-Zeev O, Ling-Liao J, Gallagher CM, Hosseini M, Yin F, Wong H, Walter P, Péterfy M. PMID: 31399538.
      View in: PubMed   Mentions:    Fields:    
    21. Disruption of IRE1a through its kinase domain attenuates multiple myeloma. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16420-16429. Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen YA, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun MG, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A. PMID: 31371506.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    22. tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay. Elife. 2019 06 25; 8. Peschek J, Walter P. PMID: 31237564.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    23. Pulmonary Iron Limitation Induced by Exogenous Type I IFN Protects Mice from Cryptococcus gattii Independently of T Cells. mBio. 2019 06 18; 10(3). Davis MJ, Moyer S, Hoke ES, Sionov E, Mayer-Barber KD, Barber DL, Cai H, Jenkins L, Walter PJ, Chang YC, Kwon-Chung KJ. PMID: 31213551.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    24. Ceapins block the unfolded protein response sensor ATF6a by inducing a neomorphic inter-organelle tether. Elife. 2019 05 31; 8. Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. PMID: 31149896.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    25. Electrospray sample injection for single-particle imaging with x-ray lasers. Sci Adv. 2019 05; 5(5):eaav8801. Bielecki J, Hantke MF, Daurer BJ, Reddy HKN, Hasse D, Larsson DSD, Gunn LH, Svenda M, Munke A, Sellberg JA, Flueckiger L, Pietrini A, Nettelblad C, Lundholm I, Carlsson G, Okamoto K, Timneanu N, Westphal D, Kulyk O, Higashiura A, van der Schot G, Loh ND, Wysong TE, Bostedt C, Gorkhover T, Iwan B, Seibert MM, Osipov T, Walter P, Hart P, Bucher M, Ulmer A, Ray D, Carini G, Ferguson KR, Andersson I, Andreasson J, Hajdu J, Maia FRNC. PMID: 31058226.
      View in: PubMed   Mentions: 3     Fields:    
    26. eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Science. 2019 05 03; 364(6439):491-495. Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A. PMID: 31048491.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    27. Abstract # 2056 Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury. Brain Behavior and Immunity. 2019 Feb 1; 76:e5. K. Krukowski, A. Chou, T. Jopson, P. Jun Zhu, M. Costa-Mattioli, P. Walter, S. Rosi. .
      View in: Publisher Site   Mentions:
    28. Small molecule ISRIB suppresses the integrated stress response within a defined window of activation. Proc Natl Acad Sci U S A. 2019 02 05; 116(6):2097-2102. Rabouw HH, Langereis MA, Anand AA, Visser LJ, de Groot RJ, Walter P, van Kuppeveld FJM. PMID: 30674674.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    29. In vitro RNA Cleavage Assays to Characterize IRE1-dependent RNA Decay. Bio-protocol. 2019 Jan 1; 9(14). G. Karagöz, Jirka Peschek, Peter Walter, Diego Acosta-Alvear. .
      View in: Publisher Site   Mentions:
    30. The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1. Elife. 2018 12 24; 7. Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P. PMID: 30582518.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    31. Confirming a critical role for death receptor 5 and caspase-8 in apoptosis induction by endoplasmic reticulum stress. Cell Death Differ. 2018 08; 25(8):1530-1531. Lam M, Lawrence DA, Ashkenazi A, Walter P. PMID: 29991746.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    32. Engineering ER-stress dependent non-conventional mRNA splicing. Elife. 2018 07 09; 7. Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P. PMID: 29985129.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    33. Development of a stress response therapy targeting aggressive prostate cancer. Sci Transl Med. 2018 05 02; 10(439). Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D. PMID: 29720449.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    34. Günter Blobel (1936-2018). Science. 2018 Apr 27; 360(6387):383. Walter P, Anderson D. PMID: 29700255.
      View in: PubMed   Mentions:    Fields:    
    35. Retraction Notice to: The Unfolded Protein Response Element IRE1a Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. Cell Host Microbe. 2018 04 11; 23(4):571. Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. PMID: 29649448.
      View in: PubMed   Mentions:
    36. Regulating ER Protein Folding Homeostasis By Distinctively Processing mRNAs. The FASEB Journal. 2018 Apr 1; 32:653.9-653.9. Weihan Li, Voytek Okreglak, Jirka Peschek, Philipp Kimmig, Peter Walter. .
      View in: Publisher Site   Mentions:
    37. Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Science. 2018 03 30; 359(6383). Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P. PMID: 29599213.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    38. An unfolded protein-induced conformational switch activates mammalian IRE1. Elife. 2017 10 03; 6. Karagöz GE, Acosta-Alvear D, Nguyen HT, Lee CP, Chu F, Walter P. PMID: 28971800.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    39. Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe. Elife. 2017 09 25; 6. Guydosh NR, Kimmig P, Walter P, Green R. PMID: 28945192.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    40. Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling. J Cell Sci. 2017 Oct 01; 130(19):3222-3233. Cohen N, Breker M, Bakunts A, Pesek K, Chas A, Argemí J, Orsi A, Gal L, Chuartzman S, Wigelman Y, Jonas F, Walter P, Ernst R, Aragón T, van Anken E, Schuldiner M. PMID: 28794014.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    41. Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):E6420-E6426. Chou A, Krukowski K, Jopson T, Zhu PJ, Costa-Mattioli M, Walter P, Rosi S. PMID: 28696288.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    42. BAX inhibitor-1 regulates autophagy by controlling the IRE1a branch of the unfolded protein response. EMBO J. 2017 06 01; 36(11):1640. Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C. PMID: 28572284.
      View in: PubMed   Mentions:    Fields:    
    43. Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proc Natl Acad Sci U S A. 2017 02 21; 114(8):E1395-E1404. Tufanli O, Telkoparan Akillilar P, Acosta-Alvear D, Kocaturk B, Onat UI, Hamid SM, Çimen I, Walter P, Weber C, Erbay E. PMID: 28137856.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    44. eIF2a-mediated translational control regulates the persistence of cocaine-induced LTP in midbrain dopamine neurons. Elife. 2016 12 13; 5. Placzek AN, Prisco GV, Khatiwada S, Sgritta M, Huang W, Krnjevic K, Kaufman RJ, Dani JA, Walter P, Costa-Mattioli M. PMID: 27960077.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    45. Multiple selection filters ensure accurate tail-anchored membrane protein targeting. Elife. 2016 12 07; 5. Rao M, Okreglak V, Chio US, Cho H, Walter P, Shan SO. PMID: 27925580.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    46. CD46 Is Amplified in High-Risk Myeloma with Gain of Chromosome 1q and Selectively Targeted By a Novel Anti-CD46 Antibody-Drug Conjugate. Blood. 2016 Dec 2; 128(22):384-384. Daniel W. Sherbenou, Blake T. Aftab, Yang Su, Christopher R. Behrens, Arun P. Wiita, Aaron C. Logan, Diego Acosta-Alvear, Byron C. Hann, Peter Walter, Xiaobo Wu, John P. Atkinson, Jeffrey L. Wolf, Thomas G. Martin, Bin Liu. .
      View in: Publisher Site   Mentions:
    47. Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells. J Clin Invest. 2016 12 01; 126(12):4640-4653. Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B. PMID: 27841764.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    48. Science as a Way of Knowing: From Protein Machines to Evidence-Based Decisions. Cell. 2016 Sep 22; 167(1):16-19. Walter P, Yamamoto KR. PMID: 27634318.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    49. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 08 09; 113(32):9015-20. Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. PMID: 27450084.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    50. Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. Elife. 2016 07 20; 5. Plate L, Cooley CB, Chen JJ, Paxman RJ, Gallagher CM, Madoux F, Genereux JC, Dobbs W, Garza D, Spicer TP, Scampavia L, Brown SJ, Rosen H, Powers ET, Walter P, Hodder P, Wiseman RL, Kelly JW. PMID: 27435961.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    51. Ceapins inhibit ATF6a signaling by selectively preventing transport of ATF6a to the Golgi apparatus during ER stress. Elife. 2016 07 20; 5. Gallagher CM, Walter P. PMID: 27435962.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    52. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6a branch. Elife. 2016 07 20; 5. Gallagher CM, Garri C, Cain EL, Ang KK, Wilson CG, Chen S, Hearn BR, Jaishankar P, Aranda-Diaz A, Arkin MR, Renslo AR, Walter P. PMID: 27435960.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    53. Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods. Curr Eye Res. 2017 02; 42(2):273-281. Rösch S, Aretzweiler C, Müller F, Walter P. PMID: 27362633.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    54. Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2a. Elife. 2016 Mar 01; 5. Placzek AN, Molfese DL, Khatiwada S, Viana Di Prisco G, Huang W, Sidrauski C, Krnjevic K, Amos CL, Ray R, Dani JA, Walter P, Salas R, Costa-Mattioli M. PMID: 26928076.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    55. Translational control by eIF2a phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine. Elife. 2016 Mar 01; 5. Huang W, Placzek AN, Viana Di Prisco G, Khatiwada S, Sidrauski C, Krnjevic K, Walter P, Dani JA, Costa-Mattioli M. PMID: 26928234.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    56. Translation from the 5' untranslated region shapes the integrated stress response. Science. 2016 Jan 29; 351(6272):aad3867. Starck SR, Tsai JC, Chen K, Shodiya M, Wang L, Yahiro K, Martins-Green M, Shastri N, Walter P. PMID: 26823435.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    57. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19; 11(8):870-80. Hearn BR, Jaishankar P, Sidrauski C, Tsai JC, Vedantham P, Fontaine SD, Walter P, Renslo AR. PMID: 26789650.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    58. Dynamics of co-translational protein targeting. Curr Opin Chem Biol. 2015 Dec; 29:79-86. Elvekrog MM, Walter P. PMID: 26517565.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    59. A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing. . 2015 Dec; 16(12):1688-98. Peschek J, Acosta-Alvear D, Mendez AS, Walter P. PMID: 26483401.
      View in: PubMed   Mentions:
    60. ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13. J Cell Biol. 2015 Sep 14; 210(6):883-90. Lang AB, John Peter AT, Walter P, Kornmann B. PMID: 26370498.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    61. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 2015 Sep 01; 4:e08153. Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. PMID: 26327694.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    62. Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic. Elife. 2015 May 19; 4. Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P. PMID: 25986605.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    63. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 2015 Apr 15; 4:e07314. Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. PMID: 25875391.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    64. The small molecule ISRIB reverses the effects of eIF2a phosphorylation on translation and stress granule assembly. Elife. 2015 Feb 26; 4. Sidrauski C, McGeachy AM, Ingolia NT, Walter P. PMID: 25719440.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    65. Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):E947-56. Osman C, Noriega TR, Okreglak V, Fung JC, Walter P. PMID: 25730886.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    66. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer. . 2015 Mar; 14(3):642-8. Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. PMID: 25564440.
      View in: PubMed   Mentions:
    67. Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1. Elife. 2014 Dec 30; 3:e05031. van Anken E, Pincus D, Coyle S, Aragón T, Osman C, Lari F, Gómez Puerta S, Korennykh AV, Walter P. PMID: 25549299.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    68. Real-time observation of signal recognition particle binding to actively translating ribosomes. Elife. 2014 Oct 30; 3. Noriega TR, Chen J, Walter P, Puglisi JD. PMID: 25358118.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    69. Lasker Award winner Peter Walter. Nat Med. 2014 Oct; 20(10):1112-4. Walter P. PMID: 25295946.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    70. Delayed Ras/PKA signaling augments the unfolded protein response. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14800-5. Pincus D, Aranda-Díaz A, Zuleta IA, Walter P, El-Samad H. PMID: 25275008.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    71. ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery. J Cell Sci. 2014 Sep 15; 127(Pt 18):4078-88. Schuck S, Gallagher CM, Walter P. PMID: 25052096.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    72. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science. 2014 Jul 04; 345(6192):98-101. Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A. PMID: 24994655.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansAnimalsCells
    73. Translational control of mGluR-dependent long-term depression and object-place learning by eIF2a. Nat Neurosci. 2014 Aug; 17(8):1073-82. Di Prisco GV, Huang W, Buffington SA, Hsu CC, Bonnen PE, Placzek AN, Sidrauski C, Krnjevic K, Kaufman RJ, Walter P, Costa-Mattioli M. PMID: 24974795.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    74. The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8019-24. Okreglak V, Walter P. PMID: 24821790.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    75. Signal recognition particle-ribosome binding is sensitive to nascent chain length. J Biol Chem. 2014 Jul 11; 289(28):19294-305. Noriega TR, Tsai A, Elvekrog MM, Petrov A, Neher SB, Chen J, Bradshaw N, Puglisi JD, Walter P. PMID: 24808175.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    76. Molecular mechanisms of hypoxic responses via unique roles of Ras1, Cdc24 and Ptp3 in a human fungal pathogen Cryptococcus neoformans. PLoS Genet. 2014 Apr; 10(4):e1004292. Chang YC, Khanal Lamichhane A, Garraffo HM, Walter PJ, Leerkes M, Kwon-Chung KJ. PMID: 24762475.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    77. Identification of key components involved in mtDNA inheritance during cell division (965.1). The FASEB Journal. 2014 Apr 1; 28. Beatriz Camacho, Christof Osman, Peter Walter. .
      View in: Publisher Site   Mentions:
    78. Heat shock transcription factor s32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli. PLoS Biol. 2013 Dec; 11(12):e1001735. Lim B, Miyazaki R, Neher S, Siegele DA, Ito K, Walter P, Akiyama Y, Yura T, Gross CA. PMID: 24358019.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    79. Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife. 2013 May 28; 2:e00498. Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. PMID: 23741617.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansAnimalsCells
    80. The unfolded protein response element IRE1a senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. . 2013 May 15; 13(5):558-569. Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. PMID: 23684307.
      View in: PubMed   Mentions:
    81. ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. Elife. 2013 May 14; 2:e00422. Murley A, Lackner LL, Osman C, West M, Voeltz GK, Walter P, Nunnari J. PMID: 23682313.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    82. Two structure papers, a call from Frankfurt airport, and how to escape from reviewer delays: an interview with Peter Walter by Miranda Robertson. BMC Biol. 2013 Apr 15; 11:34. Walter P. PMID: 23587131.
      View in: PubMed   Mentions:    Fields:    
    83. Predicting where small molecules bind at protein-protein interfaces. PLoS One. 2013; 8(3):e58583. Walter P, Metzger J, Thiel C, Helms V. PMID: 23505538.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    84. Endoplasmic reticulum stress sensing in the unfolded protein response. Cold Spring Harb Perspect Biol. 2013 Mar 01; 5(3):a013169. Gardner BM, Pincus D, Gotthardt K, Gallagher CM, Walter P. PMID: 23388626.
      View in: PubMed   Mentions: 195     Fields:    Translation:HumansAnimalsCells
    85. The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. Elife. 2012 Oct 15; 1:e00048. Kimmig P, Diaz M, Zheng J, Williams CC, Lang A, Aragón T, Li H, Walter P. PMID: 23066505.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    86. Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):E3084-93. Fordyce PM, Pincus D, Kimmig P, Nelson CS, El-Samad H, Walter P, DeRisi JL. PMID: 23054834.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    87. A quaternary equation for interdisciplinary medical research (IMR). Journal of Translational Medicine. 2012 Oct 1; 10(Suppl 2):a49. Marc Shuman, Jim Wells, K Shokat, S Bernales, P Walter, Leonard Shultz, Neal Goodwin. .
      View in: Publisher Site   Mentions:
    88. A first line of defense against ER stress. J Cell Biol. 2012 Aug 06; 198(3):277-9. Pincus D, Walter P. PMID: 22869593.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    89. Seg1 controls eisosome assembly and shape. J Cell Biol. 2012 Aug 06; 198(3):405-20. Moreira KE, Schuck S, Schrul B, Fröhlich F, Moseley JB, Walther TC, Walter P. PMID: 22869600.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    90. Structural basis of the unfolded protein response. Annu Rev Cell Dev Biol. 2012; 28:251-77. Korennykh A, Walter P. PMID: 23057742.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    91. The unfolded protein response: from stress pathway to homeostatic regulation. Science. 2011 Nov 25; 334(6059):1081-6. Walter P, Ron D. PMID: 22116877.
      View in: PubMed   Mentions: 1589     Fields:    Translation:HumansAnimalsCells
    92. Antimyeloma Effects of the Heat Shock Protein 70 Molecular Chaperone Inhibitor MAL3-101. J Oncol. 2011; 2011:232037. Braunstein MJ, Scott SS, Scott CM, Behrman S, Walter P, Wipf P, Coplan JD, Chrico W, Joseph D, Brodsky JL, Batuman O. PMID: 21977030.
      View in: PubMed   Mentions:
    93. BAX inhibitor-1 regulates autophagy by controlling the IRE1a branch of the unfolded protein response. EMBO J. 2011 Sep 16; 30(21):4465-78. Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C. PMID: 21926971.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    94. Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. Science. 2011 Sep 30; 333(6051):1891-4. Gardner BM, Walter P. PMID: 21852455.
      View in: PubMed   Mentions: 217     Fields:    Translation:Cells
    95. The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections. Proc Natl Acad Sci U S A. 2011 Aug 23; 108(34):14151-6. Kornmann B, Osman C, Walter P. PMID: 21825164.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    96. Concerted complex assembly and GTPase activation in the chloroplast signal recognition particle. Biochemistry. 2011 Aug 23; 50(33):7208-17. Nguyen TX, Chandrasekar S, Neher S, Walter P, Shan SO. PMID: 21780778.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    97. Endogenic regulation of proliferation and zinc transporters by pigment epithelial cells nonvirally transfected with PEDF. Invest Ophthalmol Vis Sci. 2011 Jul 23; 52(8):5400-7. Johnen S, Kazanskaya O, Armogan N, Stickelmann C, Stöcker M, Walter P, Thumann G. PMID: 21508100.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    98. Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1. BMC Biol. 2011 Jul 06; 9:48. Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J, Stroud RM, Zhang C, Shokat KM, Walter P. PMID: 21729334.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    99. Structural and functional basis for RNA cleavage by Ire1. BMC Biol. 2011 Jul 06; 9:47. Korennykh AV, Korostelev AA, Egea PF, Finer-Moore J, Stroud RM, Zhang C, Shokat KM, Walter P. PMID: 21729333.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    100. Presence of xenogenic mouse RNA in RPE and IPE cells cultured on mitotically inhibited 3T3 fibroblasts. Invest Ophthalmol Vis Sci. 2011 Apr 25; 52(5):2817-24. Johnen S, Wickert L, Meier M, Salz AK, Walter P, Thumann G. PMID: 21220557.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    101. Peter Walter: investigating how the ER handles secretory proteins. Interview by Sedwick Caitlin. J Cell Biol. 2011 Apr 04; 193(1):4-5. Walter P. PMID: 21464225.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    102. Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity. J Cell Biol. 2011 Apr 04; 193(1):171-84. Rubio C, Pincus D, Korennykh A, Schuck S, El-Samad H, Walter P. PMID: 21444684.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    103. A CHOP-regulated microRNA controls rhodopsin expression. J Cell Biol. 2011 Mar 21; 192(6):919-27. Behrman S, Acosta-Alvear D, Walter P. PMID: 21402790.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    104. Prediction of the exposure status of transmembrane beta barrel residues from protein sequence. J Bioinform Comput Biol. 2011 Feb; 9(1):43-65. Hayat S, Walter P, Park Y, Helms V. PMID: 21328706.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    105. Multi-Modality Imaging of Multiple Myeloma Bone Disease In Orthotopic Xenograft Models. Blood. 2010 Nov 19; 116(21):5014-5014. Diego Acosta-Alvear, Byron C Hann, Brian A Rabinovich, Marc A Shuman, Peter Walter. .
      View in: Publisher Site   Mentions:
    106. Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16113-8. Li H, Korennykh AV, Behrman SL, Walter P. PMID: 20798350.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    107. BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol. 2010 Jul 06; 8(7):e1000415. Pincus D, Chevalier MW, Aragón T, van Anken E, Vidal SE, El-Samad H, Walter P. PMID: 20625545.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    108. Automated identification of pathways from quantitative genetic interaction data. Mol Syst Biol. 2010 Jun 08; 6:379. Battle A, Jonikas MC, Walter P, Weissman JS, Koller D. PMID: 20531408.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    109. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Nat Struct Mol Biol. 2010 Jul; 17(7):901-8. Aguilar PS, Fröhlich F, Rehman M, Shales M, Ulitsky I, Olivera-Couto A, Braberg H, Shamir R, Walter P, Mann M, Ejsing CS, Krogan NJ, Walther TC. PMID: 20526336.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    110. The yeast cell fusion protein Prm1p requires covalent dimerization to promote membrane fusion. PLoS One. 2010 May 11; 5(5):e10593. Engel A, Aguilar PS, Walter P. PMID: 20485669.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    111. ERMES-mediated ER-mitochondria contacts: molecular hubs for the regulation of mitochondrial biology. J Cell Sci. 2010 May 01; 123(Pt 9):1389-93. Kornmann B, Walter P. PMID: 20410371.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    112. Structure of sterol aliphatic chains affects yeast cell shape and cell fusion during mating. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4170-5. Aguilar PS, Heiman MG, Walther TC, Engel A, Schwudke D, Gushwa N, Kurzchalia T, Walter P. PMID: 20150508.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    113. Walking along the serendipitous path of discovery. Mol Biol Cell. 2010 Jan 01; 21(1):15-7. Walter P. PMID: 20048259.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    114. Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response. J Cell Biol. 2009 Nov 16; 187(4):525-36. Schuck S, Prinz WA, Thorn KS, Voss C, Walter P. PMID: 19948500.
      View in: PubMed   Mentions: 155     Fields:    Translation:AnimalsCells
    115. Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum. J Biol Chem. 2009 Nov 27; 284(48):33623-33. Doolittle MH, Neher SB, Ben-Zeev O, Ling-Liao J, Gallagher CM, Hosseini M, Yin F, Wong H, Walter P, Péterfy M. PMID: 19783858.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    116. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol. 2009 Aug 10; 186(3):323-31. Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. PMID: 19651891.
      View in: PubMed   Mentions: 337     Fields:    Translation:AnimalsCells
    117. A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling. J Cell Biol. 2009 Jun 29; 185(7):1227-42. Fröhlich F, Moreira K, Aguilar PS, Hubner NC, Mann M, Walter P, Walther TC. PMID: 19564405.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    118. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science. 2009 Jul 24; 325(5939):477-81. Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P. PMID: 19556461.
      View in: PubMed   Mentions: 393     Fields:    Translation:AnimalsCells
    119. The unfolded protein response during prostate cancer development. Cancer Metastasis Rev. 2009 Jun; 28(1-2):219-23. So AY, de la Fuente E, Walter P, Shuman M, Bernales S. PMID: 19172382.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    120. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009 Mar 27; 323(5922):1693-7. Jonikas MC, Collins SR, Denic V, Oh E, Quan EM, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman JS, Schuldiner M. PMID: 19325107.
      View in: PubMed   Mentions: 243     Fields:    Translation:AnimalsCells
    121. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol Cell. 2009 Mar 27; 33(6):679-91. Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, Hetz C. PMID: 19328063.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    122. Divergent effects of PERK and IRE1 signaling on cell viability. PLoS One. 2009; 4(1):e4170. Lin JH, Li H, Zhang Y, Ron D, Walter P. PMID: 19137072.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCells
    123. Signal sequences activate the catalytic switch of SRP RNA. Science. 2009 Jan 02; 323(5910):127-30. Bradshaw N, Neher SB, Booth DS, Walter P. PMID: 19119234.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    124. Messenger RNA targeting to endoplasmic reticulum stress signalling sites. Nature. 2009 Feb 05; 457(7230):736-40. Aragón T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, Rubio CA, Walter P. PMID: 19079237.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    125. The unfolded protein response signals through high-order assembly of Ire1. Nature. 2009 Feb 05; 457(7230):687-93. Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J, Zhang C, Shokat KM, Stroud RM, Walter P. PMID: 19079236.
      View in: PubMed   Mentions: 230     Fields:    Translation:AnimalsCells
    126. Pil1 controls eisosome biogenesis. Mol Biol Cell. 2009 Feb; 20(3):809-18. Moreira KE, Walther TC, Aguilar PS, Walter P. PMID: 19037108.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    127. Targeting Hsp70 in Multiple Myeloma Induces Synergistic Cytotoxicity with Inhibitors of the Proteasome and of Hsp90. Blood. 2008 Nov 16; 112(11):5160-5160. Marc J Braunstein, Craig M Scott, Shannon Behrman, Peter Walter, Peter Wipf, Eric LP Smith, Sadeaqua S Scott, H. Uwe Klueppelberg, Jeffrey L Brodsky, Olcay Batuman. .
      View in: Publisher Site   Mentions:
    128. Structures of the signal recognition particle receptor from the archaeon Pyrococcus furiosus: implications for the targeting step at the membrane. PLoS One. 2008; 3(11):e3619. Egea PF, Tsuruta H, de Leon GP, Napetschnig J, Walter P, Stroud RM. PMID: 18978942.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    129. Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus. PLoS One. 2008; 3(10):e3528. Egea PF, Napetschnig J, Walter P, Stroud RM. PMID: 18953414.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    130. The in vitro and in vivo behaviour of retinal pigment epithelial cells cultured on ultrathin collagen membranes. Biomaterials. 2009 Jan; 30(3):287-94. Thumann G, Viethen A, Gaebler A, Walter P, Kaempf S, Johnen S, Salz AK. PMID: 18929407.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    131. Membrane lysis during biological membrane fusion: collateral damage by misregulated fusion machines. J Cell Biol. 2008 Oct 20; 183(2):181-6. Engel A, Walter P. PMID: 18852300.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    132. SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction. Nat Struct Mol Biol. 2008 Sep; 15(9):916-23. Neher SB, Bradshaw N, Floor SN, Gross JD, Walter P. PMID: 19172744.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    133. Helenius et al. reply. Nature. 2008 Jul 1; 454(7204):e4-e5. Jonne Helenius, Davis T. W. Ng, Cristina L. Marolda, Peter Walter, Miguel A. Valvano, Markus Aebi. .
      View in: Publisher Site   Mentions:
    134. Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature. 2008 May 29; 453(7195):657-61. Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, Terayama K, Wong JS, Vale RD, Walter P, Farese RV. PMID: 18408709.
      View in: PubMed   Mentions: 264     Fields:    Translation:AnimalsCells
    135. Endoplasmic reticulum stress in disease pathogenesis. Annu Rev Pathol. 2008; 3:399-425. Lin JH, Walter P, Yen TS. PMID: 18039139.
      View in: PubMed   Mentions: 216     Fields:    Translation:HumansAnimalsCells
    136. Pkh-kinases control eisosome assembly and organization. EMBO J. 2007 Dec 12; 26(24):4946-55. Walther TC, Aguilar PS, Fröhlich F, Chu F, Moreira K, Burlingame AL, Walter P. PMID: 18034155.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    137. In Vitro Antimyeloma Effects of Inhibitors of the Heat Shock Protein 70 (Hsp70) Molecular Chaperone. Blood. 2007 Nov 16; 110(11):1524-1524. M.J. Braunstein, C.M. Scott, S. Berman, P. Walter, P. Wipf, J.L. Brodsky, O. Batuman. .
      View in: Publisher Site   Mentions:
    138. IRE1 signaling affects cell fate during the unfolded protein response. Science. 2007 Nov 09; 318(5852):944-9. Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B, Shokat KM, Lavail MM, Walter P. PMID: 17991856.
      View in: PubMed   Mentions: 569     Fields:    Translation:HumansAnimalsCells
    139. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18079-84. Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. PMID: 17989219.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    140. Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation. J Cell Biol. 2007 Aug 13; 178(4):611-20. Shan SO, Chandrasekar S, Walter P. PMID: 17682051.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    141. X-ray structures of the signal recognition particle receptor reveal targeting cycle intermediates. PLoS One. 2007 Jul 11; 2(7):e607. Reyes CL, Rutenber E, Walter P, Stroud RM. PMID: 17622352.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    142. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol. 2007 Jul; 8(7):519-29. Ron D, Walter P. PMID: 17565364.
      View in: PubMed   Mentions: 2238     Fields:    Translation:HumansAnimalsCells
    143. The signal recognition particle (SRP) RNA links conformational changes in the SRP to protein targeting. Mol Biol Cell. 2007 Jul; 18(7):2728-34. Bradshaw N, Walter P. PMID: 17507650.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    144. ER-phagy: selective autophagy of the endoplasmic reticulum. Autophagy. 2007 May-Jun; 3(3):285-7. Bernales S, Schuck S, Walter P. PMID: 17351330.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    145. The Golgi-resident protease Kex2 acts in conjunction with Prm1 to facilitate cell fusion during yeast mating. J Cell Biol. 2007 Jan 15; 176(2):209-22. Heiman MG, Engel A, Walter P. PMID: 17210951.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    146. The plasma membrane proteins Prm1 and Fig1 ascertain fidelity of membrane fusion during yeast mating. Mol Biol Cell. 2007 Feb; 18(2):547-56. Aguilar PS, Engel A, Walter P. PMID: 17151357.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    147. Differential Effects of Hsp70 Inhibition within the Tumor and Microenvironment in Multiple Myeloma. Blood. 2006 Nov 16; 108(11):5070-5070. Marc J. Braunstein, Na Liu, Uwe Klueppelberg, Craig Scott, Shannon Behrman, Can Tamucin, Peter Walter, Peter Wipf, Jeffrey Brodsky, Olcay Batuman. .
      View in: Publisher Site   Mentions:
    148. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol. 2006 Nov; 4(12):e423. Bernales S, McDonald KL, Walter P. PMID: 17132049.
      View in: PubMed   Mentions: 344     Fields:    Translation:AnimalsCells
    149. Eisosomes mark static sites of endocytosis. Nature. 2006 Feb 23; 439(7079):998-1003. Walther TC, Brickner JH, Aguilar PS, Bernales S, Pantoja C, Walter P. PMID: 16496001.
      View in: PubMed   Mentions: 143     Fields:    Translation:AnimalsCells
    150. Intracellular signaling by the unfolded protein response. Annu Rev Cell Dev Biol. 2006; 22:487-508. Bernales S, Papa FR, Walter P. PMID: 16822172.
      View in: PubMed   Mentions: 234     Fields:    Translation:AnimalsCells
    151. On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):18773-84. Credle JJ, Finer-Moore JS, Papa FR, Stroud RM, Walter P. PMID: 16365312.
      View in: PubMed   Mentions: 194     Fields:    Translation:HumansAnimalsCells
    152. Structural basis of FFAT motif-mediated ER targeting. Structure. 2005 Jul; 13(7):1035-45. Kaiser SE, Brickner JH, Reilein AR, Fenn TD, Walter P, Brunger AT. PMID: 16004875.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    153. Molecular Crosstalk between the Nucleotide Specificity Determinant of the SRP GTPase and the SRP Receptor. Biochemistry. 2005 May 1; 44(20):7602-7602. Shu-ou Shan, Peter Walter. .
      View in: Publisher Site   Mentions:
    154. Molecular crosstalk between the nucleotide specificity determinant of the SRP GTPase and the SRP receptor. Biochemistry. 2005 Apr 26; 44(16):6214-22. Shan SO, Walter P. PMID: 15835909.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    155. Targeting proteins to membranes: structure of the signal recognition particle. Curr Opin Struct Biol. 2005 Apr; 15(2):213-20. Egea PF, Stroud RM, Walter P. PMID: 15837181.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    156. Co-translational protein targeting by the signal recognition particle. FEBS Lett. 2005 Feb 07; 579(4):921-6. Shan SO, Walter P. PMID: 15680975.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    157. Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease. Genome Biol. 2005; 6(1):R3. Niwa M, Patil CK, DeRisi J, Walter P. PMID: 15642095.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    158. Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16454-9. Chu F, Shan SO, Moustakas DT, Alber F, Egea PF, Stroud RM, Walter P, Burlingame AL. PMID: 15546976.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    159. Gene recruitment of the activated INO1 locus to the nuclear membrane. PLoS Biol. 2004 Nov; 2(11):e342. Brickner JH, Walter P. PMID: 15455074.
      View in: PubMed   Mentions: 162     Fields:    Translation:AnimalsCells
    160. Mechanism of association and reciprocal activation of two GTPases. PLoS Biol. 2004 Oct; 2(10):e320. Shan SO, Stroud RM, Walter P. PMID: 15383838.
      View in: PubMed   Mentions: 51     Fields:    Translation:Cells
    161. IRE1-independent gain control of the unfolded protein response. PLoS Biol. 2004 Aug; 2(8):E235. Leber JH, Bernales S, Walter P. PMID: 15314654.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    162. Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response. PLoS Biol. 2004 Aug; 2(8):E246. Patil CK, Li H, Walter P. PMID: 15314660.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    163. Substrate twinning activates the signal recognition particle and its receptor. Nature. 2004 Jan 15; 427(6971):215-21. Egea PF, Shan SO, Napetschnig J, Savage DF, Walter P, Stroud RM. PMID: 14724630.
      View in: PubMed   Mentions: 119     Fields:    Translation:Cells
    164. Bypassing a kinase activity with an ATP-competitive drug. Science. 2003 Nov 28; 302(5650):1533-7. Papa FR, Zhang C, Shokat K, Walter P. PMID: 14564015.
      View in: PubMed   Mentions: 97     Fields:    Translation:Cells
    165. Induced nucleotide specificity in a GTPase. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4480-5. Shan SO, Walter P. PMID: 12663860.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    166. Structural basis for mobility in the 1.1 A crystal structure of the NG domain of Thermus aquaticus Ffh. J Mol Biol. 2002 Jul 19; 320(4):783-99. Ramirez UD, Minasov G, Focia PJ, Stroud RM, Walter P, Kuhn P, Freymann DM. PMID: 12095255.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    167. Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature. 2002 Jan 24; 415(6870):447-50. Helenius J, Ng DT, Marolda CL, Walter P, Valvano MA, Aebi M. PMID: 11807558.
      View in: PubMed   Mentions: 72     Fields:    Translation:Cells
    168. 8 The Unfolded Protein Response. Protein Targeting, Transport, and Translocation. 2002 Jan 1; (Proc Natl Acad Sci USA921995):151-179. Carmela Sidrauski, Jason H. Brickner, Peter Walter. .
      View in: Publisher Site   Mentions:
    169. Role of SRP RNA in the GTPase cycles of Ffh and FtsY. Biochemistry. 2001 Dec 18; 40(50):15224-33. Peluso P, Shan SO, Nock S, Herschlag D, Walter P. PMID: 11735405.
      View in: PubMed   Mentions: 68     Fields:    Translation:Cells
    170. Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site. Nat Struct Biol. 2001 Dec; 8(12):1064-8. Ennifar E, Walter P, Ehresmann B, Ehresmann C, Dumas P. PMID: 11702070.
      View in: PubMed   Mentions: 77     Fields:    Translation:Cells
    171. Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response. Cell. 2001 Oct 05; 107(1):103-14. Rüegsegger U, Leber JH, Walter P. PMID: 11595189.
      View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
    172. Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions. J Mol Biol. 2001 Aug 03; 311(1):205-16. Senger B, Despons L, Walter P, Jakubowski H, Fasiolo F. PMID: 11469869.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    173. Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr Opin Cell Biol. 2001 Jun; 13(3):349-55. Patil C, Walter P. PMID: 11343907.
      View in: PubMed   Mentions: 234     Fields:    Translation:HumansAnimalsCells
    174. Multifaceted physiological response allows yeast to adapt to the loss of the signal recognition particle-dependent protein-targeting pathway. Mol Biol Cell. 2001 Mar; 12(3):577-88. Mutka SC, Walter P. PMID: 11251072.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    175. Basis for regulated RNA cleavage by functional analysis of RNase L and Ire1p. RNA. 2001 Mar; 7(3):361-73. Dong B, Niwa M, Walter P, Silverman RH. PMID: 11333017.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    176. Ier1 p: A Kinase and Site-Specific Endoribonuclease. Nuclease Methods and Protocols. 2001 Jan 1; 160:25-36. Tania N. Gonzalez, Peter Walter. .
      View in: Publisher Site   Mentions:
    177. Ire1p: a kinase and site-specific endoribonuclease. Methods Mol Biol. 2001; 160:25-36. Gonzalez TN, Walter P. PMID: 11265288.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    178. The signal recognition particle. Annu Rev Biochem. 2001; 70:755-75. Keenan RJ, Freymann DM, Stroud RM, Walter P. PMID: 11395422.
      View in: PubMed   Mentions: 199     Fields:    Translation:Cells
    179. Purification and activity assays of the catalytic domains of the kinase/endoribonuclease Ire1p from Saccharomyces cerevisiae. Methods Enzymol. 2001; 342:3-10. Nock S, Gonzalez TN, Sidrauski C, Niwa M, Walter P. PMID: 11586903.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    180. Pausing to decide. Proc Natl Acad Sci U S A. 2000 Nov 07; 97(23):12396-7. Niwa M, Walter P. PMID: 11058174.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    181. Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. J Cell Biol. 2000 Oct 30; 151(3):719-30. Heiman MG, Walter P. PMID: 11062271.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    182. The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control. J Cell Biol. 2000 Jul 10; 150(1):77-88. Ng DT, Spear ED, Walter P. PMID: 10893258.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    183. Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor. Science. 2000 Jun 02; 288(5471):1640-3. Peluso P, Herschlag D, Nock S, Freymann DM, Johnson AE, Walter P. PMID: 10834842.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells
    184. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell. 2000 Apr 28; 101(3):249-58. Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, Walter P. PMID: 10847680.
      View in: PubMed   Mentions: 665     Fields:    Translation:AnimalsCells
    185. Perspectives: structural biology. SRP--where the RNA and membrane worlds meet. Science. 2000 Feb 18; 287(5456):1212-3. Walter P, Keenan R, Schmitz U. PMID: 10712156.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    186. A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. Cell. 1999 Dec 23; 99(7):691-702. Niwa M, Sidrauski C, Kaufman RJ, Walter P. PMID: 10619423.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    187. Blobel's nobel: a vision validated. Cell. 1999 Dec 10; 99(6):557-8. Anderson D, Walter P. PMID: 10612390.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    188. Signal sequence recognition and protein targeting. Curr Opin Struct Biol. 1999 Dec; 9(6):754-9. Stroud RM, Walter P. PMID: 10607673.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    189. The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges. Structure. 1999 Nov 15; 7(11):1439-49. Ennifar E, Yusupov M, Walter P, Marquet R, Ehresmann B, Ehresmann C, Dumas P. PMID: 10574792.
      View in: PubMed   Mentions: 53     Fields:    Translation:Cells
    190. Structure of the phylogenetically most conserved domain of SRP RNA. RNA. 1999 Nov; 5(11):1419-29. Schmitz U, Behrens S, Freymann DM, Keenan RJ, Lukavsky P, Walter P, James TL. PMID: 10580470.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    191. Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP. Nat Struct Biol. 1999 Aug; 6(8):793-801. Freymann DM, Keenan RJ, Stroud RM, Walter P. PMID: 10426959.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    192. Structure of the most conserved internal loop in SRP RNA. Nat Struct Biol. 1999 Jul; 6(7):634-8. Schmitz U, James TL, Lukavsky P, Walter P. PMID: 10404218.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    193. Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J. 1999 Jun 01; 18(11):3119-32. Gonzalez TN, Sidrauski C, Dörfler S, Walter P. PMID: 10357823.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    194. Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell. 1999 Apr; 10(4):987-1000. Powers T, Walter P. PMID: 10198052.
      View in: PubMed   Mentions: 173     Fields:    Translation:AnimalsCells
    195. Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol-anchored proteins. Mol Biol Cell. 1999 Apr; 10(4):1043-59. Barz WP, Walter P. PMID: 10198056.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    196. Neisseria gonorrhoeae PilA is an FtsY homolog. J Bacteriol. 1999 Feb; 181(3):731-9. Arvidson CG, Powers T, Walter P, So M. PMID: 9922234.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    197. Crystallization of the dimerization-initiation site of genomic HIV-1 RNA: preliminary crystallographic results. Acta Crystallogr D Biol Crystallogr. 1999 Jan; 55(Pt 1):281-4. Yusupov M, Walter P, Marquet R, Ehresmann C, Ehresmann B, Dumas P. PMID: 10089425.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    198. A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit. J Cell Biol. 1998 Jul 27; 142(2):341-54. Ogg SC, Barz WP, Walter P. PMID: 9679135.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    199. Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell. 1998 Jul 24; 94(2):181-91. Keenan RJ, Freymann DM, Walter P, Stroud RM. PMID: 9695947.
      View in: PubMed   Mentions: 97     Fields:    Translation:Cells
    200. The unfolded protein response: an intracellular signalling pathway with many surprising features. Trends Cell Biol. 1998 Jun; 8(6):245-9. Sidrauski C, Chapman R, Walter P. PMID: 9695849.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    201. Heterodimer SRP9/14 is an integral part of the neural BC200 RNP in primate brain. Neurosci Lett. 1998 Apr 10; 245(3):123-6. Kremerskothen J, Zopf D, Walter P, Cheng JG, Nettermann M, Niewerth U, Maraia RJ, Brosius J. PMID: 9605471.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    202. Intracellular signaling from the endoplasmic reticulum to the nucleus. Annu Rev Cell Dev Biol. 1998; 14:459-85. Chapman R, Sidrauski C, Walter P. PMID: 9891790.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    203. A ribosome at the end of the tunnel. Science. 1997 Dec 19; 278(5346):2072-3. Powers T, Walter P. PMID: 9432719.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    204. Translational attenuation mediated by an mRNA intron. Curr Biol. 1997 Nov 01; 7(11):850-9. Chapman RE, Walter P. PMID: 9382810.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    205. The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell. 1997 Sep 19; 90(6):1031-9. Sidrauski C, Walter P. PMID: 9323131.
      View in: PubMed   Mentions: 301     Fields:    Translation:AnimalsCells
    206. The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane. Mol Biol Cell. 1997 Sep; 8(9):1805-14. Cox JS, Chapman RE, Walter P. PMID: 9307975.
      View in: PubMed   Mentions: 146     Fields:    Translation:AnimalsCells
    207. Co-translational protein targeting catalyzed by the Escherichia coli signal recognition particle and its receptor. EMBO J. 1997 Aug 15; 16(16):4880-6. Powers T, Walter P. PMID: 9305630.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    208. Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA. Mol Biol Cell. 1997 Jul; 8(7):1233-42. Nunnari J, Marshall WF, Straight A, Murray A, Sedat JW, Walter P. PMID: 9243504.
      View in: PubMed   Mentions: 156     Fields:    Translation:AnimalsCells
    209. Structure of the conserved GTPase domain of the signal recognition particle. Nature. 1997 Jan 23; 385(6614):361-4. Freymann DM, Keenan RJ, Stroud RM, Walter P. PMID: 9002524.
      View in: PubMed   Mentions: 80     Fields:    Translation:Cells
    210. NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP). RNA. 1996 Dec; 2(12):1213-27. Schmitz U, Freymann DM, James TL, Keenan RJ, Vinayak R, Walter P. PMID: 8972771.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    211. A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell. 1996 Nov 01; 87(3):391-404. Cox JS, Walter P. PMID: 8898193.
      View in: PubMed   Mentions: 345     Fields:    Translation:AnimalsCells
    212. tRNA ligase is required for regulated mRNA splicing in the unfolded protein response. Cell. 1996 Nov 01; 87(3):405-13. Sidrauski C, Cox JS, Walter P. PMID: 8898194.
      View in: PubMed   Mentions: 165     Fields:    Translation:AnimalsCells
    213. Progress torwards the crystal structure of Ffh, the bacterial homolog of SRP54. Acta Crystallographica Section A: Foundations and advances. 1996 Aug 8; 52(a1):c167-c167. D. Freymann, R. Keenan, R. Stroud, P. Walter. .
      View in: Publisher Site   Mentions:
    214. Signal sequences specify the targeting route to the endoplasmic reticulum membrane. J Cell Biol. 1996 Jul; 134(2):269-78. Ng DT, Brown JD, Walter P. PMID: 8707814.
      View in: PubMed   Mentions: 139     Fields:    Translation:AnimalsCells
    215. Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. EMBO J. 1996 Jun 17; 15(12):3028-39. Shamu CE, Walter P. PMID: 8670804.
      View in: PubMed   Mentions: 200     Fields:    Translation:AnimalsCells
    216. Protein targeting. The ribosome talks back. Nature. 1996 May 16; 381(6579):191-2. Powers T, Walter P. PMID: 8622754.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    217. The nascent polypeptide-associated complex modulates interactions between the signal recognition particle and the ribosome. Curr Biol. 1996 Mar 01; 6(3):331-8. Powers T, Walter P. PMID: 8805251.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    218. Regulation of organelle biogenesis. Cell. 1996 Feb 09; 84(3):389-94. Nunnari J, Walter P. PMID: 8608592.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    219. ER membrane protein complex required for nuclear fusion. J Cell Biol. 1996 Feb; 132(4):499-509. Ng DT, Walter P. PMID: 8647883.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    220. Conservation in evolution for a small monomeric phenylalanyl-tRNA synthetase of the tRNA(Phe) recognition nucleotides and initial aminoacylation site. Biochemistry. 1996 Jan 09; 35(1):117-23. Aphasizhev R, Senger B, Rengers JU, Sprinzl M, Walter P, Nussbaum G, Fasiolo F. PMID: 8555164.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    221. Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases. Science. 1995 Sep 08; 269(5229):1422-4. Powers T, Walter P. PMID: 7660124.
      View in: PubMed   Mentions: 61     Fields:    Translation:Cells
    222. An amino-terminal domain containing hydrophobic and hydrophilic sequences binds the signal recognition particle receptor alpha subunit to the beta subunit on the endoplasmic reticulum membrane. J Biol Chem. 1995 Jun 30; 270(26):15650-7. Young JC, Ursini J, Legate KR, Miller JD, Walter P, Andrews DW. PMID: 7797564.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    223. SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation. Cell. 1995 Jun 30; 81(7):1075-84. Ogg SC, Walter P. PMID: 7600575.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    224. The 70 carboxyl-terminal amino acids of nascent secretory proteins are protected from proteolysis by the ribosome and the protein translocation apparatus of the endoplasmic reticulum membrane. J Biol Chem. 1995 Mar 17; 270(11):6170-80. Matlack KE, Walter P. PMID: 7890751.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    225. The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane. J Cell Biol. 1995 Feb; 128(3):273-82. Miller JD, Tajima S, Lauffer L, Walter P. PMID: 7844142.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    226. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Harvey Lect. 1995-1996; 91:115-31. Walter P. PMID: 9127989.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    227. Targeting pathways to the endoplasmic reticulum membrane. Cold Spring Harb Symp Quant Biol. 1995; 60:23-30. Brown JD, NG DT, Ogg SC, Walter P. PMID: 8824374.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    228. Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression. EMBO J. 1994 Sep 15; 13(18):4390-400. Brown JD, Hann BC, Medzihradszky KF, Niwa M, Burlingame AL, Walter P. PMID: 7925282.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    229. Protein translocation across the endoplasmic reticulum. Curr Opin Cell Biol. 1994 Aug; 6(4):510-6. Ng DT, Walter P. PMID: 7986526.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    230. Genetic and biochemical analysis of the fission yeast ribonucleoprotein particle containing a homolog of Srp54p. Nucleic Acids Res. 1994 Jul 11; 22(13):2557-67. Selinger D, Brennwald P, Althoff S, Reich C, Hann B, Walter P, Wise JA. PMID: 8041618.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    231. Interaction of E. coli Ffh/4.5S ribonucleoprotein and FtsY mimics that of mammalian signal recognition particle and its receptor. Nature. 1994 Feb 17; 367(6464):657-9. Miller JD, Bernstein HD, Walter P. PMID: 8107852.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    232. The unfolded-protein-response pathway in yeast. Trends Cell Biol. 1994 Feb; 4(2):56-60. Shamu CE, Cox JS, Walter P. PMID: 14731868.
      View in: PubMed   Mentions: 42     Fields:    
    233. Role of the histone amino termini in facilitated binding of a transcription factor, GAL4-AH, to nucleosome cores. Mol Cell Biol. 1994 Feb; 14(2):970-81. Vettese-Dadey M, Walter P, Chen H, Juan LJ, Workman JL. PMID: 8289837.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    234. [Noninvasive studies of macro- and microcirculation in follow-up of femoropopliteal bypass operation in IIb peripheral arterial occlusive disease]. Vasa. 1994; 23(4):312-20. Scheffler P, Gross J, Dabringhaus S, de la Hamette D, Walter P. PMID: 7817611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    235. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu Rev Cell Biol. 1994; 10:87-119. Walter P, Johnson AE. PMID: 7888184.
      View in: PubMed   Mentions: 230     Fields:    Translation:HumansCells
    236. A mitochondrial protease with two catalytic subunits of nonoverlapping specificities. Science. 1993 Dec 24; 262(5142):1997-2004. Nunnari J, Fox TD, Walter P. PMID: 8266095.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    237. GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation. Nature. 1993 Nov 25; 366(6453):351-4. Miller JD, Wilhelm H, Gierasch L, Gilmore R, Walter P. PMID: 8247130.
      View in: PubMed   Mentions: 52     Fields:    Translation:Cells
    238. Shedding light on the translocation pore. Curr Biol. 1993 Oct 01; 3(10):677-9. Matlack KE, Walter P. PMID: 15335859.
      View in: PubMed   Mentions:    Fields:    
    239. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell. 1993 Jun 18; 73(6):1197-206. Cox JS, Shamu CE, Walter P. PMID: 8513503.
      View in: PubMed   Mentions: 426     Fields:    Translation:AnimalsCells
    240. Functional substitution of the signal recognition particle 54-kDa subunit by its Escherichia coli homolog. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5229-33. Bernstein HD, Zopf D, Freymann DM, Walter P. PMID: 8389475.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    241. Discrete nascent chain lengths are required for the insertion of presecretory proteins into microsomal membranes. J Cell Biol. 1993 Jun; 121(6):1211-9. Wolin SL, Walter P. PMID: 8389768.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    242. GTPase domain of the 54-kD subunit of the mammalian signal recognition particle is required for protein translocation but not for signal sequence binding. J Cell Biol. 1993 Mar; 120(5):1113-21. Zopf D, Bernstein HD, Walter P. PMID: 8382204.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    243. A GTPase cycle in initiation of protein translocation across the endoplasmic reticulum membrane. Ciba Found Symp. 1993; 176:147-59; discussion 159-63. Miller JD, Walter P. PMID: 8299417.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    244. The SRP-Dependent Protein Targeting Pathway in Saccharomyces Cerevisiae. Protein Synthesis and Targeting in Yeast. 1993 Jan 1; 283-292. Peter Walter, Stephen C. Ogg, Byron C. Hann. .
      View in: Publisher Site   Mentions:
    245. Signal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae. Mol Biol Cell. 1992 Aug; 3(8):895-911. Ogg SC, Poritz MA, Walter P. PMID: 1327299.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    246. Protein targeting to and translocation across the membrane of the endoplasmic reticulum. Curr Opin Cell Biol. 1992 Aug; 4(4):573-80. Nunnari J, Walter P. PMID: 1419037.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    247. Fluorescence-detected assembly of the signal recognition particle: binding of the two SRP protein heterodimers to SRP RNA is noncooperative. Biochemistry. 1992 Jun 30; 31(25):5830-40. Janiak F, Walter P, Johnson AE. PMID: 1377027.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    248. Binding of the yeast tRNA(Met) anticodon by the cognate methionyl-tRNA synthetase involves at least two independent peptide regions. J Mol Biol. 1992 Jun 05; 225(3):897-907. Despons L, Senger B, Fasiolo F, Walter P. PMID: 1602489.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    249. Protein translocation. Travelling by TRAM. Nature. 1992 May 07; 357(6373):22-3. Walter P. PMID: 1315419.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    250. SEC65 gene product is a subunit of the yeast signal recognition particle required for its integrity. Nature. 1992 Apr 09; 356(6369):532-3. Hann BC, Stirling CJ, Walter P. PMID: 1313947.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    251. Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae. J Cell Biol. 1992 Feb; 116(3):597-604. Green N, Fang H, Walter P. PMID: 1730771.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    252. C-terminal sequences can inhibit the insertion of membrane proteins into the endoplasmic reticulum of Saccharomyces cerevisiae. Mol Cell Biol. 1992 Jan; 12(1):276-82. Green N, Walter P. PMID: 1729604.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    253. Chapter 11 The role of GTP in protein targeting to the endoplasmic reticulum. Membrane Biogenesis and Protein Targeting. 1992 Jan 1; 22:129-136. Stephen C. Ogg, Jodi M. Nunnari, Joshua D. Miller, Peter Walter. .
      View in: Publisher Site   Mentions:
    254. Characterization of the rough endoplasmic reticulum ribosome-binding activity. Trends in Cell Biology. 1991 Nov 1; 1(5):115. J.M. Nunnari, D.L. Zimmerman, S.C. Ogg, P. Walter. .
      View in: Publisher Site   Mentions:
    255. The signal recognition particle in S. cerevisiae. Cell. 1991 Oct 04; 67(1):131-44. Hann BC, Walter P. PMID: 1655273.
      View in: PubMed   Mentions: 104     Fields:    Translation:Animals
    256. An ATP-binding membrane protein is required for protein translocation across the endoplasmic reticulum membrane. Cell Regul. 1991 Oct; 2(10):851-9. Zimmerman DL, Walter P. PMID: 1801920.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    257. Evolution of aminoacyl-tRNA synthetase quaternary structure and activity: Saccharomyces cerevisiae mitochondrial phenylalanyl-tRNA synthetase. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8387-91. Sanni A, Walter P, Boulanger Y, Ebel JP, Fasiolo F. PMID: 1924298.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    258. Identification of potential amino acid residues supporting anticodon recognition in yeast methionyl-tRNA synthetase. FEBS Lett. 1991 Sep 09; 289(2):217-20. Despons L, Walter P, Senger B, Ebel JP, Fasiolo F. PMID: 1915850.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    259. Characterization of the rough endoplasmic reticulum ribosome-binding activity. Nature. 1991 Aug 15; 352(6336):638-40. Nunnari JM, Zimmerman DL, Ogg SC, Walter P. PMID: 1650916.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    260. Binding sites of the 9- and 14-kilodalton heterodimeric protein subunit of the signal recognition particle (SRP) are contained exclusively in the Alu domain of SRP RNA and contain a sequence motif that is conserved in evolution. Mol Cell Biol. 1991 Aug; 11(8):3949-59. Strub K, Moss J, Walter P. PMID: 1712900.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    261. Small ribonucleoproteins. Current Opinion in Structural Biology. 1991 Apr 1; 1(2):251-257. Sandra L. Wolin, Peter Walter. .
      View in: Publisher Site   Mentions:
    262. A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation. J Cell Biol. 1991 Mar; 112(5):809-21. Thrift RN, Andrews DW, Walter P, Johnson AE. PMID: 1999459.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    263. The methionine-rich domain of the 54 kd protein subunit of the signal recognition particle contains an RNA binding site and can be crosslinked to a signal sequence. EMBO J. 1990 Dec; 9(13):4511-7. Zopf D, Bernstein HD, Johnson AE, Walter P. PMID: 1702385.
      View in: PubMed   Mentions: 79     Fields:    Translation:Cells
    264. An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science. 1990 Nov 23; 250(4984):1111-7. Poritz MA, Bernstein HD, Strub K, Zopf D, Wilhelm H, Walter P. PMID: 1701272.
      View in: PubMed   Mentions: 111     Fields:    Translation:Cells
    265. Yeast methionyl-tRNA synthetase: analysis of the N-terminal extension and the putative tRNA anticodon binding region by site-directed mutagenesis. Biochimie. 1990 Aug; 72(8):537-44. Walter P, Despons L, Laforet M, Ebel JP, Fasiolo F. PMID: 2126459.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    266. Reconstitution of protein translocation activity from partially solubilized microsomal vesicles. J Biol Chem. 1990 Mar 05; 265(7):4048-53. Zimmerman DL, Walter P. PMID: 2105958.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    267. Assembly of the Alu domain of the signal recognition particle (SRP): dimerization of the two protein components is required for efficient binding to SRP RNA. Mol Cell Biol. 1990 Feb; 10(2):777-84. Strub K, Walter P. PMID: 2153922.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    268. Signal recognition particle mediates a transient elongation arrest of preprolactin in reticulocyte lysate. J Cell Biol. 1989 Dec; 109(6 Pt 1):2617-22. Wolin SL, Walter P. PMID: 2556403.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    269. Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth. J Cell Biol. 1989 Dec; 109(6 Pt 2):3223-30. Hann BC, Poritz MA, Walter P. PMID: 2557350.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    270. Isolation of a cDNA clone of the 14-kDa subunit of the signal recognition particle by cross-hybridization of differently primed polymerase chain reactions. Proc Natl Acad Sci U S A. 1989 Dec; 86(24):9747-51. Strub K, Walter P. PMID: 2557625.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    271. Protein translocation across the endoplasmic reticulum membrane: identification by photocross-linking of a 39-kD integral membrane glycoprotein as part of a putative translocation tunnel. J Cell Biol. 1989 Nov; 109(5):2033-43. Krieg UC, Johnson AE, Walter P. PMID: 2808520.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    272. Cytosolic protein translocation factors. Is SRP still unique? Cell. 1989 Sep 22; 58(6):1017-9. Bernstein HD, Rapoport TA, Walter P. PMID: 2550141.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    273. Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle. Nature. 1989 Aug 10; 340(6233):482-6. Bernstein HD, Poritz MA, Strub K, Hoben PJ, Brenner S, Walter P. PMID: 2502718.
      View in: PubMed   Mentions: 153     Fields:    Translation:AnimalsCells
    274. Cassette mutagenic analysis of the yeast invertase signal peptide: effects on protein translocation. Mol Cell Biol. 1989 Aug; 9(8):3400-10. Ngsee JK, Hansen W, Walter P, Smith M. PMID: 2677671.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    275. Assembly of proteins in the endoplasmic reticulum. Curr Opin Cell Biol. 1989 Aug; 1(4):635-8. Siegel V, Walter P. PMID: 2697275.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    276. Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor. J Cell Biol. 1989 Mar; 108(3):797-810. Andrews DW, Lauffer L, Walter P, Lingappa VR. PMID: 2537835.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    277. The use of gene-fusions to determine membrane protein topology in Saccharomyces cerevisiae. J Cell Sci Suppl. 1989; 11:109-13. Green GN, Hansen W, Walter P. PMID: 2693456.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    278. Ribosome pausing and stacking during translation of a eukaryotic mRNA. EMBO J. 1988 Nov; 7(11):3559-69. Wolin SL, Walter P. PMID: 2850168.
      View in: PubMed   Mentions: 181     Fields:    Translation:AnimalsCells
    279. Isolation and characterization of a cDNA clone encoding the 19 kDa protein of signal recognition particle (SRP): expression and binding to 7SL RNA. Nucleic Acids Res. 1988 Oct 25; 16(20):9431-42. Lingelbach K, Zwieb C, Webb JR, Marshallsay C, Hoben PJ, Walter P, Dobberstein B. PMID: 2460823.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    280. Human SRP RNA and E. coli 4.5S RNA contain a highly homologous structural domain. Cell. 1988 Oct 07; 55(1):4-6. Poritz MA, Strub K, Walter P. PMID: 2458843.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    281. Functional dissection of the signal recognition particle. Trends Biochem Sci. 1988 Aug; 13(8):314-6. Siegel V, Walter P. PMID: 2856455.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    282. The affinity of signal recognition particle for presecretory proteins is dependent on nascent chain length. EMBO J. 1988 Jun; 7(6):1769-75. Siegel V, Walter P. PMID: 3169004.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    283. Small ribonucleoproteins in Schizosaccharomyces pombe and Yarrowia lipolytica homologous to signal recognition particle. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4315-9. Poritz MA, Siegel V, Hansen W, Walter P. PMID: 2837764.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    284. Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro. Nature. 1988 May 05; 333(6168):90-3. Kassenbrock CK, Garcia PD, Walter P, Kelly RB. PMID: 3129663.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
    285. Prepro-carboxypeptidase Y and a truncated form of pre-invertase, but not full-length pre-invertase, can be posttranslationally translocated across microsomal vesicle membranes from Saccharomyces cerevisiae. J Cell Biol. 1988 Apr; 106(4):1075-81. Hansen W, Walter P. PMID: 3283144.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    286. Targeting of the hepatitis B virus precore protein to the endoplasmic reticulum membrane: after signal peptide cleavage translocation can be aborted and the product released into the cytoplasm. J Cell Biol. 1988 Apr; 106(4):1093-104. Garcia PD, Ou JH, Rutter WJ, Walter P. PMID: 3283145.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    287. Full-length prepro-alpha-factor can be translocated across the mammalian microsomal membrane only if translation has not terminated. J Cell Biol. 1988 Apr; 106(4):1043-8. Garcia PD, Walter P. PMID: 2834400.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    288. Binding sites of the 19-kDa and 68/72-kDa signal recognition particle (SRP) proteins on SRP RNA as determined in protein-RNA "footprinting". Proc Natl Acad Sci U S A. 1988 Mar; 85(6):1801-5. Siegel V, Walter P. PMID: 2450348.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    289. Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: analysis of biochemical mutants of SRP. Cell. 1988 Jan 15; 52(1):39-49. Siegel V, Walter P. PMID: 2830980.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    290. Evidence for an extended 7SL RNA structure in the signal recognition particle. EMBO J. 1987 Nov; 6(11):3471-7. Andrews DW, Walter P, Ottensmeyer FP. PMID: 2828031.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    291. Substrate requirements for SRP-mediated targeting to the ER membrane. Molecular Biology Reports. 1987 Sep 1; 12(3):219-219. V. Siegel, P. D. Garcia, P. Walter. .
      View in: Publisher Site   Mentions:
    292. Functional dissection of the signal recognition particle. Molecular Biology Reports. 1987 Sep 1; 12(3):220-220. V. Siegel, M. Poritz, P. Walter. .
      View in: Publisher Site   Mentions:
    293. Signal recognition. Two receptors act sequentially. Nature. 1987 Aug 27-Sep 2; 328(6133):763-4. Walter P. PMID: 3041220.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    294. Wild type and mutant signal peptides of Escherichia coli outer membrane lipoprotein interact with equal efficiency with mammalian signal recognition particle. J Biol Chem. 1987 Jul 15; 262(20):9463-8. Garcia PD, Ghrayeb J, Inouye M, Walter P. PMID: 3298258.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    295. Mathematical modeling of the effects of the signal recognition particle on translation and translocation of proteins across the endoplasmic reticulum membrane. J Mol Biol. 1987 Jun 05; 195(3):621-36. Rapoport TA, Heinrich R, Walter P, Schulmeister T. PMID: 2821280.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    296. Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle. Proc Natl Acad Sci U S A. 1986 Nov; 83(22):8604-8. Krieg UC, Walter P, Johnson AE. PMID: 3095839.
      View in: PubMed   Mentions: 113     Fields:    Translation:Cells
    297. The signal recognition particle receptor is a complex that contains two distinct polypeptide chains. J Cell Biol. 1986 Oct; 103(4):1167-78. Tajima S, Lauffer L, Rath VL, Walter P. PMID: 3021779.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    298. In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factor. Cell. 1986 May 09; 45(3):397-406. Hansen W, Garcia PD, Walter P. PMID: 3009026.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    299. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature. 1986 Mar 13-19; 320(6058):134-9. Green S, Walter P, Kumar V, Krust A, Bornert JM, Argos P, Chambon P. PMID: 3754034.
      View in: PubMed   Mentions: 427     Fields:    Translation:HumansCells
    300. Removal of the Alu structural domain from signal recognition particle leaves its protein translocation activity intact. Nature. 1986 Mar 6-12; 320(6057):81-4. Siegel V, Walter P. PMID: 2419765.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    301. Mechanism of protein translocation across the endoplasmic reticulum membrane. Annu Rev Cell Biol. 1986; 2:499-516. Walter P, Lingappa VR. PMID: 3030381.
      View in: PubMed   Mentions: 152     Fields:    Translation:AnimalsCells
    302. Structure and Function of the Signal Recognition Particle. Genetic Engineering. 1986 Jan 1; 181-196. Vivian Siegel, Peter Walter. .
      View in: Publisher Site   Mentions:
    303. The Protein Translocation Machinery of the Endoplasmic Reticulum: The Signal Hypothesis Ten Years Later. Protein Compartmentalization. 1986 Jan 1; 1-13. Peter Walter, Vivian Siegel, Leander Lauffer, Pablo D. Garcia. .
      View in: Publisher Site   Mentions:
    304. Intracellular Protein Topogenesis. New Insights into Cell and Membrane Transport Processes. 1986 Jan 1; 277-283. Günter Blobel, Peter Walter, Reid Gilmore. .
      View in: Publisher Site   Mentions:
    305. Topology of signal recognition particle receptor in endoplasmic reticulum membrane. Nature. 1985 Nov 28-Dec 4; 318(6044):334-8. Lauffer L, Garcia PD, Harkins RN, Coussens L, Ullrich A, Walter P. PMID: 2999608.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    306. Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane. J Cell Biol. 1985 Jun; 100(6):1913-21. Siegel V, Walter P. PMID: 2581979.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    307. Structure of the signal recognition particle by electron microscopy. Proc Natl Acad Sci U S A. 1985 Feb; 82(3):785-9. Andrews DW, Walter P, Ottensmeyer FP. PMID: 3856232.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    308. Protein translocation across the endoplasmic reticulum. Cell. 1984 Aug; 38(1):5-8. Walter P, Gilmore R, Blobel G. PMID: 6088076.
      View in: PubMed   Mentions: 190     Fields:    Translation:AnimalsCells
    309. Role of signal recognition particle in the membrane assembly of Sindbis viral glycoproteins. Eur J Biochem. 1984 May 02; 140(3):499-502. Bonatti S, Migliaccio G, Blobel G, Walter P. PMID: 6723645.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    310. Subcellular distribution of signal recognition particle and 7SL-RNA determined with polypeptide-specific antibodies and complementary DNA probe. J Cell Biol. 1983 Dec; 97(6):1693-9. Walter P, Blobel G. PMID: 6196367.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    311. Disassembly and reconstitution of signal recognition particle. Cell. 1983 Sep; 34(2):525-33. Walter P, Blobel G. PMID: 6413076.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    312. Translocation of a lysosomal enzyme across the microsomal membrane requires signal recognition particle. Biochem Biophys Res Commun. 1983 Aug 30; 115(1):275-80. Erickson AH, Walter P, Blobel G. PMID: 6137219.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    313. Signal recognition particle: a ribonucleoprotein required for cotranslational translocation of proteins, isolation and properties. Methods Enzymol. 1983; 96:682-91. Walter P, Blobel G. PMID: 6197610.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    314. The protein translocation machinery of the endoplasmic reticulum. Philos Trans R Soc Lond B Biol Sci. 1982 Dec 24; 300(1099):225-8. Walter P, Gilmore R, Müller M, Blobel G. PMID: 6131460.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    315. Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle. J Cell Biol. 1982 Nov; 95(2 Pt 1):463-9. Gilmore R, Blobel G, Walter P. PMID: 6292235.
      View in: PubMed   Mentions: 117     Fields:    Translation:Cells
    316. Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor. J Cell Biol. 1982 Nov; 95(2 Pt 1):470-7. Gilmore R, Walter P, Blobel G. PMID: 6292236.
      View in: PubMed   Mentions: 163     Fields:    Translation:Cells
    317. A bacterial secretory protein requires signal recognition particle for translocation across mammalian endoplasmic reticulum. J Biol Chem. 1982 Oct 25; 257(20):11860-3. Müller M, Ibrahimi I, Chang CN, Walter P, Blobel G. PMID: 6749848.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    318. Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum. Nature. 1982 Oct 21; 299(5885):691-8. Walter P, Blobel G. PMID: 6181418.
      View in: PubMed   Mentions: 246     Fields:    Translation:AnimalsCells
    319. Signal recognition protein is required for the integration of acetylcholine receptor delta subunit, a transmembrane glycoprotein, into the endoplasmic reticulum membrane. J Cell Biol. 1982 May; 93(2):501-6. Anderson DJ, Walter P, Blobel G. PMID: 7047541.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    320. Mechanism of protein translocation across the endoplasmic reticulum. Biochem Soc Symp. 1982; 47:183-91. Walter P, Blobel G. PMID: 6100822.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    321. THE PROTEIN TRANSLOCATION MACHINERY OF THE ENDOPLASMIC RETICULUM. Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression. 1982 Jan 1; 291-293. PETER WALTER, REID GILMORE, MATTHIAS MULLER, GUNTER BLOBEL. .
      View in: Publisher Site   Mentions:
    322. Translocation of proteins across the endoplasmic reticulum. Oncodev Biol Med. 1982; 4(1-2):137-46. Walter P, Blobel G. PMID: 7177879.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    323. Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol. 1981 Nov; 91(2 Pt 1):545-50. Walter P, Ibrahimi I, Blobel G. PMID: 7309795.
      View in: PubMed   Mentions: 207     Fields:    Translation:AnimalsCells
    324. Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol. 1981 Nov; 91(2 Pt 1):551-6. Walter P, Blobel G. PMID: 7309796.
      View in: PubMed   Mentions: 112     Fields:    Translation:AnimalsCells
    325. Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes. J Cell Biol. 1981 Nov; 91(2 Pt 1):557-61. Walter P, Blobel G. PMID: 7309797.
      View in: PubMed   Mentions: 250     Fields:    Translation:AnimalsCells
    326. Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum. Proc Natl Acad Sci U S A. 1980 Dec; 77(12):7112-6. Walter P, Blobel G. PMID: 6938958.
      View in: PubMed   Mentions: 178     Fields:    Translation:AnimalsCells
    327. Secretion requires a cytoplasmically disposed sulphydryl of the RER membrane. Nature. 1980 Jul 10; 286(5769):174-6. Jackson RC, Walter P, Blobel G. PMID: 6995850.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    328. Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol. 1979; 33:9-36. Blobel G, Walter P, Chang CN, Goldman BM, Erickson AH, Lingappa VR. PMID: 524275.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    Peter's Networks
    Concepts (791)
    Derived automatically from this person's publications.
    _
    Co-Authors (70)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _