Jonathan Weissman, PhD

Title(s)Professor, Cellular Molecular Pharmacology
SchoolSchool of Medicine
Address1700 4th Street, #001
San Francisco CA 94158
Phone415-502-8089
vCardDownload vCard
    Other Positions
    Title(s)Professor, School of Medicine


    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    The Cancer Target Discovery and Development Network at UCSF
    NIH U01CA217882Aug 10, 2017 - Jul 31, 2022
    Role: Co-Principal Investigator
    Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming
    NIH R01DA036858Sep 30, 2013 - May 31, 2018
    Role: Principal Investigator
    Structural Basis of Protein Homeostasis
    NIH U01GM098254Sep 30, 2012 - Jul 31, 2016
    Role: Co-Principal Investigator
    Human Gene Knockdowns that May Extend Lifespan
    NIH R01AG041826May 1, 2012 - Apr 30, 2018
    Role: Principal Investigator
    Bay Area Cancer Target Discovery and Development Network
    NIH U01CA168370May 1, 2012 - Apr 30, 2017
    Role: Co-Principal Investigator
    MECHANISM OF CHAPERONE MEDIATED PROTEIN FOLDING
    NIH R01GM055595May 1, 1997 - Apr 30, 2002
    Role: Principal Investigator
    Molecular Pathogenesis of Age-Dependent CNS Regeneration
    NIH P01AG010770Apr 1, 1993 - Mar 31, 2016
    Role: Co-Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Spatiotemporal modeling of molecular holograms. Cell. 2025 Mar 01. Qiu X, Zhu DY, Lu Y, Yao J, Jing Z, Min KH, Cheng M, Pan H, Zuo L, King S, Fang Q, Zheng H, Wang M, Wang S, Zhang Q, Yu S, Liao S, Liu C, Wu X, Lai Y, Hao S, Zhang Z, Wu L, Zhang Y, Li M, Tu Z, Lin J, Yang Z, Li Y, Gu Y, Ellison D, Lu YR, Hu Q, Hu Y, Chen A, Liu L, Weissman JS, Ma J, Xu X, Liu S, Bai Y. PMID: 40024251.
      View in: PubMed   Mentions:
    2. A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function. bioRxiv. 2025 Feb 17. Saunders RA, Allen WE, Pan X, Sandhu J, Lu J, Lau TK, Smolyar K, Sullivan ZA, Dulac C, Weissman JS, Zhuang X. PMID: 39605605; PMCID: PMC11601512.
      View in: PubMed   Mentions:
    3. CD47 predominates over CD24 as a macrophage immune checkpoint in cancer. bioRxiv. 2024 Nov 26. Allen J, Meglan A, Vaccaro K, Velarde J, Chen V, Ribeiro J, Blandin J, Gupta S, Mishra R, Ho R, Love J, Reinhardt F, Bell GW, Chen J, Weinberg R, Yang D, Weissman J, Weiskopf K. PMID: 39651307; PMCID: PMC11623506.
      View in: PubMed   Mentions:
    4. FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer. bioRxiv. 2024 Nov 21. Menon S, Gracilla D, Breese MR, Lin YP, Cruz FD, Feinberg T, de Stanchina E, Galic AF, Allegakoen H, Perati S, Wen N, Heslin A, Horlbeck MA, Weissman J, Sweet-Cordero EA, Bivona TG, Tulpule A. PMID: 37205599; PMCID: PMC10187251.
      View in: PubMed   Mentions:
    5. Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death. bioRxiv. 2024 Nov 19. Lam B, Kajderowicz KM, Keys HR, Roessler JM, Frenkel EM, Kirkland A, Bisht P, El-Brolosy MA, Jaenisch R, Bell GW, Weissman JS, Griffith EC, Hrvatin S. PMID: 39091747; PMCID: PMC11291167.
      View in: PubMed   Mentions:
    6. Spatiotemporal modeling of molecular holograms. Cell. 2024 Dec 26; 187(26):7351-7373.e61. Qiu X, Zhu DY, Lu Y, Yao J, Jing Z, Min KH, Cheng M, Pan H, Zuo L, King S, Fang Q, Zheng H, Wang M, Wang S, Zhang Q, Yu S, Liao S, Liu C, Wu X, Lai Y, Hao S, Zhang Z, Wu L, Zhang Y, Li M, Tu Z, Lin J, Yang Z, Li Y, Gu Y, Ellison D, Chen A, Liu L, Weissman JS, Ma J, Xu X, Liu S, Bai Y. PMID: 39532097.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry. bioRxiv. 2024 Oct 28. Wilson CM, Pommier GC, Richman DD, Sambold N, Hussmann JA, Weissman JS, Gilbert LA. PMID: 39554033; PMCID: PMC11565746.
      View in: PubMed   Mentions:
    8. Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis. bioRxiv. 2024 Oct 24. Jones MG, Sun D, Min KHJ, Colgan WN, Tian L, Weir JA, Chen VZ, Koblan LW, Yost KE, Mathey-Andrews N, Russell AJC, Stickels RR, Balderrama KS, Rideout WM, Chang HY, Jacks T, Chen F, Weissman JS, Yosef N, Yang D. PMID: 39484491; PMCID: PMC11526908.
      View in: PubMed   Mentions:
    9. High-quality peptide evidence for annotating non-canonical open reading frames as human proteins. bioRxiv. 2024 Sep 09. Deutsch EW, Kok LW, Mudge JM, Ruiz-Orera J, Fierro-Monti I, Sun Z, Abelin JG, Alba MM, Aspden JL, Bazzini AA, Bruford EA, Brunet MA, Calviello L, Carr SA, Carvunis AR, Chothani S, Clauwaert J, Dean K, Faridi P, Frankish A, Hubner N, Ingolia NT, Magrane M, Martin MJ, Martinez TF, Menschaert G, Ohler U, Orchard S, Rackham O, Roucou X, Slavoff SA, Valen E, Wacholder A, Weissman JS, Wu W, Xie Z, Choudhary J, Bassani-Sternberg M, Vizcaíno JA, Ternette N, Moritz RL, Prensner JR, van Heesch S. PMID: 39314370; PMCID: PMC11419116.
      View in: PubMed   Mentions:
    10. Robustness and reliability of single-cell regulatory multi-omics with deep mitochondrial mutation profiling. bioRxiv. 2024 Aug 24. Weng C, Weissman JS, Sankaran VG. PMID: 39229039; PMCID: PMC11370557.
      View in: PubMed   Mentions:
    11. Transcriptome-wide characterization of genetic perturbations. bioRxiv. 2024 Jul 03. Nadig A, Replogle JM, Pogson AN, McCarroll SA, Weissman JS, Robinson EB, O'Connor LJ. PMID: 39005298; PMCID: PMC11244993.
      View in: PubMed   Mentions:
    12. Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor. Science. 2024 Jun 28; 384(6703):ado7082. Neumann EN, Bertozzi TM, Wu E, Serack F, Harvey JW, Brauer PP, Pirtle CP, Coffey A, Howard M, Kamath N, Lenz K, Guzman K, Raymond MH, Khalil AS, Deverman BE, Minikel EV, Vallabh SM, Weissman JS. PMID: 38935715.
      View in: PubMed   Mentions: 3     Fields:    
    13. Author Correction: CRISPR technologies for genome, epigenome and transcriptome editing. Nat Rev Mol Cell Biol. 2024 Jun; 25(6):510. Villiger L, Joung J, Koblan L, Weissman J, Abudayyeh OO, Gootenberg JS. PMID: 38740926.
      View in: PubMed   Mentions: 1     Fields:    
    14. Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress. Dev Cell. 2024 Aug 19; 59(16):2203-2221.e15. Do BT, Hsu PP, Vermeulen SY, Wang Z, Hirz T, Abbott KL, Aziz N, Replogle JM, Bjelosevic S, Paolino J, Nelson SA, Block S, Darnell AM, Ferreira R, Zhang H, Milosevic J, Schmidt DR, Chidley C, Harris IS, Weissman JS, Pikman Y, Stegmaier K, Cheloufi S, Su XA, Sykes DB, Vander Heiden MG. PMID: 38823395; PMCID: PMC11444020.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    15. CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling. Proc Natl Acad Sci U S A. 2024 May 28; 121(22):e2322524121. Halasz H, Malekos E, Covarrubias S, Yitiz S, Montano C, Sudek L, Katzman S, Liu SJ, Horlbeck MA, Namvar L, Weissman JS, Carpenter S. PMID: 38781216; PMCID: PMC11145268.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nat Neurosci. 2024 May; 27(5):822-835. Hacisuleyman E, Hale CR, Noble N, Luo JD, Fak JJ, Saito M, Chen J, Weissman JS, Darnell RB. PMID: 38589584; PMCID: PMC11088998.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    17. Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology. Mol Cell. 2024 Mar 21; 84(6):1101-1119.e9. Muthukumar G, Stevens TA, Inglis AJ, Esantsi TK, Saunders RA, Schulte F, Voorhees RM, Guna A, Weissman JS. PMID: 38428433.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    18. CRISPR technologies for genome, epigenome and transcriptome editing. Nat Rev Mol Cell Biol. 2024 Jun; 25(6):464-487. Villiger L, Joung J, Koblan L, Weissman J, Abudayyeh OO, Gootenberg JS. PMID: 38308006.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    19. Deciphering cell states and genealogies of human haematopoiesis. Nature. 2024 Mar; 627(8003):389-398. Weng C, Yu F, Yang D, Poeschla M, Liggett LA, Jones MG, Qiu X, Wahlster L, Caulier A, Hussmann JA, Schnell A, Yost KE, Koblan LW, Martin-Rufino JD, Min J, Hammond A, Ssozi D, Bueno R, Mallidi H, Kreso A, Escabi J, Rideout WM, Jacks T, Hormoz S, van Galen P, Weissman JS, Sankaran VG. PMID: 38253266; PMCID: PMC10937407.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    20. Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning. Nat Biotechnol. 2023 Nov; 41(11):1655. Koblan LW, Arbab M, Shen MW, Hussmann JA, Anzalone AV, Doman JL, Newby GA, Yang D, Mok B, Replogle JM, Xu A, Sisley TA, Weissman JS, Adamson B, Liu DR. PMID: 37853259.
      View in: PubMed   Mentions: 4     Fields:    
    21. A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens. BMC Genomics. 2023 Oct 30; 24(1):651. Guna A, Page KR, Replogle JM, Esantsi TK, Wang ML, Weissman JS, Voorhees RM. PMID: 37904134; PMCID: PMC10614335.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    22. Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq. Nat Commun. 2023 10 06; 14(1):6245. Sunshine S, Puschnik AS, Replogle JM, Laurie MT, Liu J, Zha BS, Nuñez JK, Byrum JR, McMorrow AH, Frieman MB, Winkler J, Qiu X, Rosenberg OS, Leonetti MD, Ye CJ, Weissman JS, DeRisi JL, Hein MY. PMID: 37803001; PMCID: PMC10558542.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    23. Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology. bioRxiv. 2023 Aug 17. Muthukumar G, Stevens TA, Inglis AJ, Esantsi TK, Saunders RA, Schulte F, Voorhees RM, Guna A, Weissman JS. PMID: 37645817; PMCID: PMC10462106.
      View in: PubMed   Mentions:
    24. A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens. bioRxiv. 2023 Aug 14. Guna A, Page KR, Replogle JM, Esantsi TK, Wang ML, Weissman JS, Voorhees RM. PMID: 36711738; PMCID: PMC9882262.
      View in: PubMed   Mentions:
    25. Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity. Nucleic Acids Res. 2023 07 07; 51(12):6355-6369. She R, Luo J, Weissman JS. PMID: 37144468; PMCID: PMC10325891.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. Comparative landscape of genetic dependencies in human and chimpanzee stem cells. Cell. 2023 07 06; 186(14):2977-2994.e23. She R, Fair T, Schaefer NK, Saunders RA, Pavlovic BJ, Weissman JS, Pollen AA. PMID: 37343560; PMCID: PMC10461406.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    27. FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer. Res Sq. 2023 May 29. Menon S, Breese MR, Lin YP, Allegakoen H, Perati S, Heslin A, Horlbeck MA, Weissman J, Sweet-Cordero EA, Bivona TG, Tulpule A. PMID: 37398210; PMCID: PMC10312925.
      View in: PubMed   Mentions:
    28. Coupled protein quality control during nonsense-mediated mRNA decay. J Cell Sci. 2023 05 15; 136(10). Inglis AJ, Guna A, Gálvez-Merchán Á, Pal A, Esantsi TK, Keys HR, Frenkel EM, Oania R, Weissman JS, Voorhees RM. PMID: 37218462; PMCID: PMC10234110.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    29. Comparative landscape of genetic dependencies in human and chimpanzee stem cells. bioRxiv. 2023 Mar 20. She R, Fair T, Schaefer NK, Saunders RA, Pavlovic BJ, Weissman JS, Pollen AA. PMID: 36993685; PMCID: PMC10055274.
      View in: PubMed   Mentions:
    30. Microfluidics-free single-cell genomics with templated emulsification. Nat Biotechnol. 2023 Nov; 41(11):1557-1566. Clark IC, Fontanez KM, Meltzer RH, Xue Y, Hayford C, May-Zhang A, D'Amato C, Osman A, Zhang JQ, Hettige P, Ishibashi JSA, Delley CL, Weisgerber DW, Replogle JM, Jost M, Phong KT, Kennedy VE, Peretz CAC, Kim EA, Song S, Karlon W, Weissman JS, Smith CC, Gartner ZJ, Abate AR. PMID: 36879006; PMCID: PMC10635830.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    31. Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. Elife. 2022 12 28; 11. Replogle JM, Bonnar JL, Pogson AN, Liem CR, Maier NK, Ding Y, Russell BJ, Wang X, Leng K, Guna A, Norman TM, Pak RA, Ramos DM, Ward ME, Gilbert LA, Kampmann M, Weissman JS, Jost M. PMID: 36576240; PMCID: PMC9829409.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    32. GATOR2-dependent mTORC1 activity is a therapeutic vulnerability in FOXO1 fusion-positive rhabdomyosarcoma. JCI Insight. 2022 12 08; 7(23). Morales J, Allegakoen DV, Garcia JA, Kwong K, Sahu PK, Fajardo DA, Pan Y, Horlbeck MA, Weissman JS, Gustafson WC, Bivona TG, Sabnis AJ. PMID: 36282590; PMCID: PMC9746907.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    33. MTCH2 is a mitochondrial outer membrane protein insertase. Science. 2022 10 21; 378(6617):317-322. Guna A, Stevens TA, Inglis AJ, Replogle JM, Esantsi TK, Muthukumar G, Shaffer KCL, Wang ML, Pogson AN, Jones JJ, Lomenick B, Chou TF, Weissman JS, Voorhees RM. PMID: 36264797; PMCID: PMC9674023.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    34. Cellular barcoding to decipher clonal dynamics in disease. Science. 2022 10 14; 378(6616):eabm5874. Sankaran VG, Weissman JS, Zon LI. PMID: 36227997; PMCID: PMC10111813.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    35. Dual genome-wide coding and lncRNA screens in neural induction of induced pluripotent stem cells. Cell Genom. 2022 Nov 09; 2(11). Wu D, Poddar A, Ninou E, Hwang E, Cole MA, Liu SJ, Horlbeck MA, Chen J, Replogle JM, Carosso GA, Eng NWL, Chang J, Shen Y, Weissman JS, Lim DA. PMID: 36381608; PMCID: PMC9648144.
      View in: PubMed   Mentions: 11     Fields:    
    36. Adaptive exchange sustains cullin-RING ubiquitin ligase networks and proper licensing of DNA replication. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2205608119. Zhang Y, Jost M, Pak RA, Lu D, Li J, Lomenick B, Garbis SD, Li CM, Weissman JS, Lipford JR, Deshaies RJ. PMID: 36037385; PMCID: PMC9456757.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    37. Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice. Nat Biotechnol. 2022 12; 40(12):1834-1844. Tolani B, Celli A, Yao Y, Tan YZ, Fetter R, Liem CR, de Smith AJ, Vasanthakumar T, Bisignano P, Cotton AD, Seiple IB, Rubinstein JL, Jost M, Weissman JS. PMID: 35879364; PMCID: PMC9750872.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    38. A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities. Cell Chem Biol. 2022 08 18; 29(8):1303-1316.e3. Shao H, Taguwa S, Gilbert L, Shkedi A, Sannino S, Guerriero CJ, Gale-Day ZJ, Young ZT, Brodsky JL, Weissman J, Gestwicki JE, Frydman J. PMID: 35830852; PMCID: PMC9513760.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    39. Standardized annotation of translated open reading frames. Nat Biotechnol. 2022 07; 40(7):994-999. Mudge JM, Ruiz-Orera J, Prensner JR, Brunet MA, Calvet F, Jungreis I, Gonzalez JM, Magrane M, Martinez TF, Schulz JF, Yang YT, Albà MM, Aspden JL, Baranov PV, Bazzini AA, Bruford E, Martin MJ, Calviello L, Carvunis AR, Chen J, Couso JP, Deutsch EW, Flicek P, Frankish A, Gerstein M, Hubner N, Ingolia NT, Kellis M, Menschaert G, Moritz RL, Ohler U, Roucou X, Saghatelian A, Weissman JS, van Heesch S. PMID: 35831657; PMCID: PMC9757701.
      View in: PubMed   Mentions: 82     Fields:    Translation:Cells
    40. Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq. Cell. 2022 07 07; 185(14):2559-2575.e28. Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS. PMID: 35688146; PMCID: PMC9380471.
      View in: PubMed   Mentions: 151     Fields:    
    41. Variant to function mapping at single-cell resolution through network propagation. Nat Biotechnol. 2022 11; 40(11):1644-1653. Yu F, Cato LD, Weng C, Liggett LA, Jeon S, Xu K, Chiang CWK, Wiemels JL, Wiemels JL, Weissman JS, de Smith AJ, Sankaran VG. PMID: 35668323; PMCID: PMC9646486.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    42. Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution. Cell. 2022 05 26; 185(11):1905-1923.e25. Yang D, Jones MG, Naranjo S, Rideout WM, Min KHJ, Ho R, Wu W, Replogle JM, Page JL, Quinn JJ, Horns F, Qiu X, Chen MZ, Freed-Pastor WA, McGinnis CS, Patterson DM, Gartner ZJ, Chow ED, Bivona TG, Chan MM, Yosef N, Jacks T, Weissman JS. PMID: 35523183; PMCID: PMC9452598.
      View in: PubMed   Mentions: 88     Fields:    Translation:Animals
    43. OpenCell: Endogenous tagging for the cartography of human cellular organization. Science. 2022 03 11; 375(6585):eabi6983. Cho NH, Cheveralls KC, Brunner AD, Kim K, Michaelis AC, Raghavan P, Kobayashi H, Savy L, Li JY, Canaj H, Kim JYS, Stewart EM, Gnann C, McCarthy F, Cabrera JP, Brunetti RM, Chhun BB, Dingle G, Hein MY, Huang B, Mehta SB, Weissman JS, Gómez-Sjöberg R, Itzhak DN, Royer LA, Mann M, Leonetti MD. PMID: 35271311; PMCID: PMC9119736.
      View in: PubMed   Mentions: 168     Fields:    Translation:HumansCells
    44. High-content CRISPR screening. Nat Rev Methods Primers. 2022; 2(1). Bock C, Datlinger P, Chardon F, Coelho MA, Dong MB, Lawson KA, Lu T, Maroc L, Norman TM, Song B, Stanley G, Chen S, Garnett M, Li W, Moffat J, Qi LS, Shapiro RS, Shendure J, Weissman JS, Zhuang X. PMID: 37214176; PMCID: PMC10200264.
      View in: PubMed   Mentions: 153  
    45. Mapping transcriptomic vector fields of single cells. Cell. 2022 02 17; 185(4):690-711.e45. Qiu X, Zhang Y, Martin-Rufino JD, Weng C, Hosseinzadeh S, Yang D, Pogson AN, Hein MY, Hoi Joseph Min K, Wang L, Grody EI, Shurtleff MJ, Yuan R, Xu S, Ma Y, Replogle JM, Lander ES, Darmanis S, Bahar I, Sankaran VG, Xing J, Weissman JS. PMID: 35108499; PMCID: PMC9332140.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansCells
    46. Variant to function mapping at single-cell resolution through network propagation. bioRxiv. 2022 Jan 24. Yu F, Cato LD, Weng C, Liggett LA, Jeon S, Xu K, Chiang CWK, Wiemels JL, Wiemels JL, Weissman JS, de Smith AJ, Sankaran VG. PMID: 35118467; PMCID: PMC8811900.
      View in: PubMed   Mentions:
    47. BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2. Nat Cell Biol. 2022 01; 24(1):24-34. Samelson AJ, Tran QD, Robinot R, Carrau L, Rezelj VV, Kain AM, Chen M, Ramadoss GN, Guo X, Lim SA, Lui I, Nuñez JK, Rockwood SJ, Wang J, Liu N, Carlson-Stevermer J, Oki J, Maures T, Holden K, Weissman JS, Wells JA, Conklin BR, TenOever BR, Chakrabarti LA, Vignuzzi M, Tian R, Kampmann M. PMID: 35027731; PMCID: PMC8820466.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    48. Peroxisome function relies on organelle-associated mRNA translation. Sci Adv. 2022 Jan 14; 8(2):eabk2141. Dahan N, Bykov YS, Boydston EA, Fadel A, Gazi Z, Hochberg-Laufer H, Martenson J, Denic V, Shav-Tal Y, Weissman JS, Aviram N, Zalckvar E, Schuldiner M. PMID: 35020435; PMCID: PMC8754406.
      View in: PubMed   Mentions: 9     Fields:    
    49. The dark proteome: translation from noncanonical open reading frames. Trends Cell Biol. 2022 03; 32(3):243-258. Wright BW, Yi Z, Weissman JS, Chen J. PMID: 34844857; PMCID: PMC8934435.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimals
    50. Functional single-cell genomics of human cytomegalovirus infection. Nat Biotechnol. 2022 03; 40(3):391-401. Hein MY, Weissman JS. PMID: 34697476.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    51. Mapping the genetic landscape of DNA double-strand break repair. Cell. 2021 Oct 28; 184(22):5653-5669.e25. Hussmann JA, Ling J, Ravisankar P, Yan J, Cirincione A, Xu A, Simpson D, Yang D, Bothmer A, Cotta-Ramusino C, Weissman JS, Adamson B. PMID: 34672952; PMCID: PMC9074467.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    52. Enhanced prime editing systems by manipulating cellular determinants of editing outcomes. Cell. 2021 10 28; 184(22):5635-5652.e29. Chen PJ, Hussmann JA, Yan J, Knipping F, Ravisankar P, Chen PF, Chen C, Nelson JW, Newby GA, Sahin M, Osborn MJ, Weissman JS, Adamson B, Liu DR. PMID: 34653350; PMCID: PMC8584034.
      View in: PubMed   Mentions: 254     Fields:    Translation:HumansCells
    53. BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2. bioRxiv. 2021 Sep 20. Samelson AJ, Tran QD, Robinot R, Carrau L, Rezelj VV, Mac Kain A, Chen M, Ramadoss GN, Guo X, Lim SA, Lui I, Nunez J, Rockwood SJ, Wang J, Liu N, Carlson-Stevermer J, Oki J, Maures T, Holden K, Weissman JS, Wells JA, Conklin BR, TenOever BR, Chakrabarti LA, Vignuzzi M, Tian R, Kampmann M. PMID: 33501440; PMCID: PMC7836110.
      View in: PubMed   Mentions:
    54. Structured elements drive extensive circular RNA translation. Mol Cell. 2021 10 21; 81(20):4300-4318.e13. Chen CK, Cheng R, Demeter J, Chen J, Weingarten-Gabbay S, Jiang L, Snyder MP, Weissman JS, Segal E, Jackson PK, Chang HY. PMID: 34437836; PMCID: PMC8567535.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansCells
    55. An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. Elife. 2021 08 20; 10. Coukos R, Yao D, Sanchez MI, Strand ET, Olive ME, Udeshi ND, Weissman JS, Carr SA, Bassik MC, Ting AY. PMID: 34414886; PMCID: PMC8423448.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    56. Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning. Nat Biotechnol. 2021 Nov; 39(11):1414-1425. Koblan LW, Arbab M, Shen MW, Hussmann JA, Anzalone AV, Doman JL, Newby GA, Yang D, Mok B, Replogle JM, Xu A, Sisley TA, Weissman JS, Adamson B, Liu DR. PMID: 34183861; PMCID: PMC8985520.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    57. Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells. Elife. 2021 05 26; 10. Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J. PMID: 34034859; PMCID: PMC8154037.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    58. CRISPR-based functional genomics in human dendritic cells. Elife. 2021 04 27; 10. Jost M, Jacobson AN, Hussmann JA, Cirolia G, Fischbach MA, Weissman JS. PMID: 33904395; PMCID: PMC8104964.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    59. Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell. 2021 04 29; 184(9):2503-2519.e17. Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS. PMID: 33838111; PMCID: PMC8376083.
      View in: PubMed   Mentions: 240     Fields:    Translation:HumansCells
    60. Regulation of translation by methylation multiplicity of 18S rRNA. Cell Rep. 2021 03 09; 34(10):108825. Liu K, Santos DA, Hussmann JA, Wang Y, Sutter BM, Weissman JS, Tu BP. PMID: 33691096; PMCID: PMC8063911.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    61. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell. 2021 Feb 04; 184(3):844. Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. PMID: 33545038.
      View in: PubMed   Mentions: 24     Fields:    
    62. High-content imaging-based pooled CRISPR screens in mammalian cells. J Cell Biol. 2021 02 01; 220(2). Yan X, Stuurman N, Ribeiro SA, Tanenbaum ME, Horlbeck MA, Liem CR, Jost M, Weissman JS, Vale RD. PMID: 33465779; PMCID: PMC7821101.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    63. Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts. Science. 2021 02 26; 371(6532). Quinn JJ, Jones MG, Okimoto RA, Nanjo S, Chan MM, Yosef N, Bivona TG, Weissman JS. PMID: 33479121; PMCID: PMC7983364.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    64. A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation. Cancer Discov. 2021 06; 11(6):1562-1581. Lo YH, Kolahi KS, Du Y, Chang CY, Krokhotin A, Nair A, Sobba WD, Karlsson K, Jones SJ, Longacre TA, Mah AT, Tercan B, Sockell A, Xu H, Seoane JA, Chen J, Shmulevich I, Weissman JS, Curtis C, Califano A, Fu H, Crabtree GR, Kuo CJ. PMID: 33451982; PMCID: PMC8346515.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    65. Genome-Scale Perturbation of Long Noncoding RNA Expression Using CRISPR Interference. Methods Mol Biol. 2021; 2254:323-338. Liu SJ, Horlbeck MA, Weissman JS, Lim DA. PMID: 33326085; PMCID: PMC7917014.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    66. Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. Elife. 2020 11 25; 9. Miller-Vedam LE, Bräuning B, Popova KD, Schirle Oakdale NT, Bonnar JL, Prabu JR, Boydston EA, Sevillano N, Shurtleff MJ, Stroud RM, Craik CS, Schulman BA, Frost A, Weissman JS. PMID: 33236988; PMCID: PMC7785296.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    67. Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis. Cell Syst. 2020 11 18; 11(5):523-535.e9. Hawkins JS, Silvis MR, Koo BM, Peters JM, Osadnik H, Jost M, Hearne CC, Weissman JS, Todor H, Gross CA. PMID: 33080209; PMCID: PMC7704046.
      View in: PubMed   Mentions: 58     Fields:    Translation:Cells
    68. Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway. Curr Biol. 2020 10 05; 30(19):3775-3787.e7. Jiménez-Rojo N, Leonetti MD, Zoni V, Colom A, Feng S, Iyengar NR, Matile S, Roux A, Vanni S, Weissman JS, Riezman H. PMID: 32857977.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    69. Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing. Cell. 2020 09 03; 182(5):1232-1251.e22. Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG. PMID: 32822576; PMCID: PMC7484178.
      View in: PubMed   Mentions: 278     Fields:    Translation:HumansCells
    70. Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span. Sci Adv. 2020 08; 6(32):eaba1306. Zou K, Rouskin S, Dervishi K, McCormick MA, Sasikumar A, Deng C, Chen Z, Kaeberlein M, Brem RB, Polymenis M, Kennedy BK, Weissman JS, Zheng J, Ouyang Q, Li H. PMID: 32821821; PMCID: PMC7406366.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    71. GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control. Mol Cell. 2020 09 17; 79(6):950-962.e6. Hickey KL, Dickson K, Cogan JZ, Replogle JM, Schoof M, D'Orazio KN, Sinha NK, Hussmann JA, Jost M, Frost A, Green R, Weissman JS, Kostova KK. PMID: 32726578; PMCID: PMC7891188.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    72. Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent. Mol Cell. 2020 07 02; 79(1):191-198.e3. Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. PMID: 32619469; PMCID: PMC7332992.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCellsPHPublic Health
    73. Polysomes Bypass a 50-Nucleotide Coding Gap Less Efficiently Than Monosomes Due to Attenuation of a 5' mRNA Stem-Loop and Enhanced Drop-off. J Mol Biol. 2020 07 24; 432(16):4369-4387. O'Loughlin S, Capece MC, Klimova M, Wills NM, Coakley A, Samatova E, O'Connor PBF, Loughran G, Weissman JS, Baranov PV, Rodnina MV, Puglisi JD, Atkins JF. PMID: 32454154; PMCID: PMC7245268.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    74. Inference of single-cell phylogenies from lineage tracing data using Cassiopeia. Genome Biol. 2020 04 14; 21(1):92. Jones MG, Khodaverdian A, Quinn JJ, Chan MM, Hussmann JA, Wang R, Xu C, Weissman JS, Yosef N. PMID: 32290857; PMCID: PMC7155257.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    75. CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma. Genome Biol. 2020 03 31; 21(1):83. Liu SJ, Malatesta M, Lien BV, Saha P, Thombare SS, Hong SJ, Pedraza L, Koontz M, Seo K, Horlbeck MA, He D, Birk HS, Jain M, Olsen HE, Akeson M, Weissman JS, Monje M, Gupta N, Raleigh DR, Ullian EM, Lim DA. PMID: 32234056; PMCID: PMC7110660.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    76. Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing. Nat Biotechnol. 2020 Aug; 38(8):954-961. Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, Weissman JS, Adamson B. PMID: 32231336; PMCID: PMC7416462.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansCells
    77. Pervasive functional translation of noncanonical human open reading frames. Science. 2020 03 06; 367(6482):1140-1146. Chen J, Brunner AD, Cogan JZ, Nuñez JK, Fields AP, Adamson B, Itzhak DN, Li JY, Mann M, Leonetti MD, Weissman JS. PMID: 32139545; PMCID: PMC7289059.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansCells
    78. Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes. Nat Biotechnol. 2020 May; 38(5):573-576. Horlbeck MA, Liu SJ, Chang HY, Lim DA, Weissman JS. PMID: 32094656; PMCID: PMC8128075.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    79. Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs. Nat Biotechnol. 2020 Mar; 38(3):355-364. Jost M, Santos DA, Saunders RA, Horlbeck MA, Hawkins JS, Scaria SM, Norman TM, Hussmann JA, Liem CR, Gross CA, Weissman JS. PMID: 31932729; PMCID: PMC7065968.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    80. The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration. Genes Dev. 2020 02 01; 34(3-4):194-208. Vargas EJM, Matamoros AJ, Qiu J, Jan CH, Wang Q, Gorczyca D, Han TW, Weissman JS, Jan YN, Banerjee S, Song Y. PMID: 31919191; PMCID: PMC7000917.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    81. Variation in expenditure for common, high cost surgical procedures in a working age population: implications for reimbursement reform. BMC Health Serv Res. 2019 Nov 21; 19(1):877. Wynn-Jones W, Koehlmoos TP, Tompkins C, Navathe A, Lipsitz S, Kwon NK, Learn PA, Madsen C, Schoenfeld A, Weissman JS. PMID: 31752866; PMCID: PMC6873455.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    82. The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins. Elife. 2019 09 13; 8. Ngo AM, Shurtleff MJ, Popova KD, Kulsuptrakul J, Weissman JS, Puschnik AS. PMID: 31516121; PMCID: PMC6756788.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    83. New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells. J Cell Biol. 2019 11 04; 218(11):3861-3879. Bassaganyas L, Popa SJ, Horlbeck M, Puri C, Stewart SE, Campelo F, Ashok A, Butnaru CM, Brouwers N, Heydari K, Ripoche J, Weissman J, Rubinsztein DC, Schekman R, Malhotra V, Moreau K, Villeneuve J. PMID: 31488582; PMCID: PMC6829651.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    84. Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science. 2019 08 23; 365(6455):786-793. Norman TM, Horlbeck MA, Replogle JM, Ge AY, Xu A, Jost M, Gilbert LA, Weissman JS. PMID: 31395745; PMCID: PMC6746554.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    85. MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices. Nat Methods. 2019 07; 16(7):619-626. McGinnis CS, Patterson DM, Winkler J, Conrad DN, Hein MY, Srivastava V, Hu JL, Murrow LM, Weissman JS, Werb Z, Chow ED, Gartner ZJ. PMID: 31209384; PMCID: PMC6837808.
      View in: PubMed   Mentions: 260     Fields:    Translation:HumansAnimalsCells
    86. Cycloheximide can distort measurements of mRNA levels and translation efficiency. Nucleic Acids Res. 2019 06 04; 47(10):4974-4985. Santos DA, Shi L, Tu BP, Weissman JS. PMID: 30916348; PMCID: PMC6547433.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    87. Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. Elife. 2019 05 31; 8. Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. PMID: 31149896; PMCID: PMC6588346.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    88. Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11291-11298. Igbaria A, Merksamer PI, Trusina A, Tilahun F, Johnson JR, Brandman O, Krogan NJ, Weissman JS, Papa FR. PMID: 31101715; PMCID: PMC6561268.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    89. Molecular recording of mammalian embryogenesis. Nature. 2019 06; 570(7759):77-82. Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. PMID: 31086336; PMCID: PMC7229772.
      View in: PubMed   Mentions: 154     Fields:    Translation:AnimalsCells
    90. Ribosome Profiling: Global Views of Translation. Cold Spring Harb Perspect Biol. 2019 05 01; 11(5). Ingolia NT, Hussmann JA, Weissman JS. PMID: 30037969; PMCID: PMC6496350.
      View in: PubMed   Mentions: 128     Fields:    Translation:Cells
    91. Cellular response to small molecules that selectively stall protein synthesis by the ribosome. PLoS Genet. 2019 03; 15(3):e1008057. Liaud N, Horlbeck MA, Gilbert LA, Gjoni K, Weissman JS, Cate JHD. PMID: 30875366; PMCID: PMC6436758.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    92. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Mol Cell. 2019 04 04; 74(1):32-44.e8. Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, Farese RV. PMID: 30846318; PMCID: PMC7696670.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    93. Mapping the Genetic Landscape of Human Cells. Cell. 2018 08 09; 174(4):953-967.e22. Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. PMID: 30033366; PMCID: PMC6426455.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansCells
    94. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). J Med Chem. 2018 Jul 26; 61(14):6163-6177. Shao H, Li X, Moses MA, Gilbert LA, Kalyanaraman C, Young ZT, Chernova M, Journey SN, Weissman JS, Hann B, Jacobson MP, Neckers L, Gestwicki JE. PMID: 29953808; PMCID: PMC6104643.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    95. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. 2018 07; 559(7714):405-409. Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, Chen JW, Schickel JN, Pellerin L, Carmody D, Alkorta-Aranburu G, Del Gaudio D, Matsumoto H, Morell M, Mao Y, Cho M, Quadros RM, Gurumurthy CB, Smith B, Haugwitz M, Hughes SH, Weissman JS, Schumann K, Esensten JH, May AP, Ashworth A, Kupfer GM, Greeley SAW, Bacchetta R, Meffre E, Roncarolo MG, Romberg N, Herold KC, Ribas A, Leonetti MD, Marson A. PMID: 29995861; PMCID: PMC6239417.
      View in: PubMed   Mentions: 388     Fields:    Translation:HumansAnimalsCells
    96. Engineering ER-stress dependent non-conventional mRNA splicing. Elife. 2018 07 09; 7. Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P. PMID: 29985129; PMCID: PMC6037481.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    97. The helicase Ded1p controls use of near-cognate translation initiation codons in 5' UTRs. Nature. 2018 07; 559(7712):130-134. Guenther UP, Weinberg DE, Zubradt MM, Tedeschi FA, Stawicki BN, Zagore LL, Brar GA, Licatalosi DD, Bartel DP, Weissman JS, Jankowsky E. PMID: 29950728; PMCID: PMC6226265.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    98. The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. Elife. 2018 05 29; 7. Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH, Weissman JS. PMID: 29809151; PMCID: PMC5995541.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    99. Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform. Hepatology. 2018 Aug; 68(2):663-676. Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. PMID: 29091290; PMCID: PMC5930141.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    100. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates. Elife. 2018 05 10; 7. Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. PMID: 29745899; PMCID: PMC6021172.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    101. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. 2018 05 31; 173(6):1398-1412.e22. Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, Weissman JS, Curtis C, Chang HY. PMID: 29731168; PMCID: PMC5984165.
      View in: PubMed   Mentions: 251     Fields:    Translation:HumansAnimalsCells
    102. A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation. Mol Cell. 2018 04 19; 70(2):274-286.e7. Zhang Y, Burkhardt DH, Rouskin S, Li GW, Weissman JS, Gross CA. PMID: 29628307; PMCID: PMC5910227.
      View in: PubMed   Mentions: 78     Fields:    Translation:Cells
    103. CRISPR Approaches to Small Molecule Target Identification. ACS Chem Biol. 2018 02 16; 13(2):366-375. Jost M, Weissman JS. PMID: 29261286; PMCID: PMC5834945.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    104. Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins. Elife. 2018 01 23; 7. Martinko AJ, Truillet C, Julien O, Diaz JE, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans MJ, Wells JA. PMID: 29359686; PMCID: PMC5796798.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    105. Defining the physiological role of SRP in protein-targeting efficiency and specificity. Science. 2018 02 09; 359(6376):689-692. Costa EA, Subramanian K, Nunnari J, Weissman JS. PMID: 29348368; PMCID: PMC5970945.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    106. Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER. Dev Cell. 2018 01 22; 44(2):261-270.e6. Friedman JR, Kannan M, Toulmay A, Jan CH, Weissman JS, Prinz WA, Nunnari J. PMID: 29290583; PMCID: PMC5975648.
      View in: PubMed   Mentions: 46     Fields:    Translation:Cells
    107. The Human Cell Atlas. Elife. 2017 12 05; 6. Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N, Human Cell Atlas Meeting Participants. PMID: 29206104; PMCID: PMC5762154.
      View in: PubMed   Mentions: 955     Fields:    
    108. Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors. Nat Methods. 2017 Dec; 14(12):1163-1166. Tak YE, Kleinstiver BP, Nuñez JK, Hsu JY, Horng JE, Gong J, Weissman JS, Joung JK. PMID: 29083402; PMCID: PMC5909187.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    109. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Mol Cell. 2017 Oct 05; 68(1):210-223.e6. Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. PMID: 28985505; PMCID: PMC5640507.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    110. CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Science. 2017 07 28; 357(6349):414-417. Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, Weinberg DE, Weissman JS. PMID: 28751611; PMCID: PMC5673106.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    111. Minimally invasive surgery and its impact on 30-day postoperative complications, unplanned readmissions and mortality. Br J Surg. 2017 Sep; 104(10):1372-1381. Sood A, Meyer CP, Abdollah F, Sammon JD, Sun M, Lipsitz SR, Hollis M, Weissman JS, Menon M, Trinh QD. PMID: 28632890.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    112. Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia. Blood. 2017 06 01; 129(22):3000-3008. Kruth KA, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA. PMID: 28424165; PMCID: PMC5454339.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    113. Operon mRNAs are organized into ORF-centric structures that predict translation efficiency. Elife. 2017 01 31; 6. Burkhardt DH, Rouskin S, Zhang Y, Li GW, Weissman JS, Gross CA. PMID: 28139975; PMCID: PMC5318159.
      View in: PubMed   Mentions: 81     Fields:    Translation:Cells
    114. Translation from unconventional 5' start sites drives tumour initiation. Nature. 2017 01 26; 541(7638):494-499. Sendoel A, Dunn JG, Rodriguez EH, Naik S, Gomez NC, Hurwitz B, Levorse J, Dill BD, Schramek D, Molina H, Weissman JS, Fuchs E. PMID: 28077873; PMCID: PMC5287289.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansAnimalsCells
    115. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016 Dec 15; 167(7):1853-1866.e17. Dixit A, Parnas O, Li B, Chen J, Fulco CP, Jerby-Arnon L, Marjanovic ND, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman TM, Lander ES, Weissman JS, Friedman N, Regev A. PMID: 27984732; PMCID: PMC5181115.
      View in: PubMed   Mentions: 644     Fields:    Translation:HumansAnimalsCells
    116. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15; 167(7):1867-1882.e21. Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS. PMID: 27984733; PMCID: PMC5315571.
      View in: PubMed   Mentions: 475     Fields:    Translation:HumansAnimalsCells
    117. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 01 06; 355(6320). Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, Weissman JS, Lim DA. PMID: 27980086; PMCID: PMC5394926.
      View in: PubMed   Mentions: 364     Fields:    Translation:HumansCells
    118. The mTOR Complex Controls HIV Latency. Cell Host Microbe. 2016 Dec 14; 20(6):785-797. Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E. PMID: 27978436; PMCID: PMC5354304.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCells
    119. The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. Nature. 2016 11 30; 540(7631):134-138. Aviram N, Ast T, Costa EA, Arakel EC, Chuartzman SG, Jan CH, Haßdenteufel S, Dudek J, Jung M, Schorr S, Zimmermann R, Schwappach B, Weissman JS, Schuldiner M. PMID: 27905431; PMCID: PMC5513701.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    120. Plastid: nucleotide-resolution analysis of next-generation sequencing and genomics data. BMC Genomics. 2016 11 22; 17(1):958. Dunn JG, Weissman JS. PMID: 27875984; PMCID: PMC5120557.
      View in: PubMed   Mentions: 91     Fields:    
    121. Model-guided optogenetic study of PKA signaling in budding yeast. Mol Biol Cell. 2017 01 01; 28(1):221-227. Stewart-Ornstein J, Chen S, Bhatnagar R, Weissman JS, El-Samad H. PMID: 28035051; PMCID: PMC5221627.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    122. DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo. Nat Methods. 2017 01; 14(1):75-82. Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. PMID: 27819661; PMCID: PMC5508988.
      View in: PubMed   Mentions: 213     Fields:    Translation:HumansCells
    123. Dynamic translation regulation in Caulobacter cell cycle control. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):E6859-E6867. Schrader JM, Li GW, Childers WS, Perez AM, Weissman JS, Shapiro L, McAdams HH. PMID: 27791168; PMCID: PMC5098616.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    124. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23; 5. Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. PMID: 27661255; PMCID: PMC5094855.
      View in: PubMed   Mentions: 382     Fields:    Translation:HumansAnimalsCells
    125. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 08 09; 113(32):9015-20. Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. PMID: 27450084; PMCID: PMC4987817.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    126. Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity. Nat Commun. 2016 07 01; 7:12009. Nguyen DP, Miyaoka Y, Gilbert LA, Mayerl SJ, Lee BH, Weissman JS, Conklin BR, Wells JA. PMID: 27363581; PMCID: PMC4932181.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    127. Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation. Proc Natl Acad Sci U S A. 2016 07 12; 113(28):E4015-24. Liu YC, Fujimori DG, Weissman JS. PMID: 27357682; PMCID: PMC4948361.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    128. Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):E3892-900. Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT. PMID: 27325776; PMCID: PMC4941480.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    129. A scalable strategy for high-throughput GFP tagging of endogenous human proteins. Proc Natl Acad Sci U S A. 2016 06 21; 113(25):E3501-8. Leonetti MD, Sekine S, Kamiyama D, Weissman JS, Huang B. PMID: 27274053; PMCID: PMC4922190.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    130. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. Cell. 2016 Jun 02; 165(6):1493-1506. Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CHS, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA. PMID: 27238023; PMCID: PMC4894308.
      View in: PubMed   Mentions: 327     Fields:    Translation:Cells
    131. Single-cell analysis of long non-coding RNAs in the developing human neocortex. Genome Biol. 2016 Apr 14; 17:67. Liu SJ, Nowakowski TJ, Pollen AA, Lui JH, Horlbeck MA, Attenello FJ, He D, Weissman JS, Kriegstein AR, Diaz AA, Lim DA. PMID: 27081004; PMCID: PMC4831157.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansCells
    132. Versatile protein tagging in cells with split fluorescent protein. Nat Commun. 2016 Mar 18; 7:11046. Kamiyama D, Sekine S, Barsi-Rhyne B, Hu J, Chen B, Gilbert LA, Ishikawa H, Leonetti MD, Marshall WF, Weissman JS, Huang B. PMID: 26988139; PMCID: PMC4802074.
      View in: PubMed   Mentions: 195     Fields:    Translation:HumansCells
    133. Nucleosomes impede Cas9 access to DNA in vivo and in vitro. Elife. 2016 03 17; 5. Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tjian R, Weissman JS. PMID: 26987018; PMCID: PMC4861601.
      View in: PubMed   Mentions: 213     Fields:    Translation:HumansCells
    134. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. 2016 Apr 07; 18(4):541-53. Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. PMID: 26971820; PMCID: PMC4830697.
      View in: PubMed   Mentions: 243     Fields:    Translation:HumansCells
    135. A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. Mol Cell. 2015 Dec 03; 60(5):816-827. Fields AP, Rodriguez EH, Jovanovic M, Stern-Ginossar N, Haas BJ, Mertins P, Raychowdhury R, Hacohen N, Carr SA, Ingolia NT, Regev A, Weissman JS. PMID: 26638175; PMCID: PMC4720255.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    136. [KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis. Mol Cell. 2015 Nov 19; 60(4):651-60. Suzuki G, Weissman JS, Tanaka M. PMID: 26590718; PMCID: PMC5513702.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    137. Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis. Cancer Cell. 2015 Nov 09; 28(5):653-665. Anderson DJ, Le Moigne R, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Kiss von Soly S, Madriaga A, Soriano F, Menon MK, Wu ZY, Kampmann M, Chen Y, Weissman JS, Aftab BT, Yakes FM, Shawver L, Zhou HJ, Wustrow D, Rolfe M. PMID: 26555175; PMCID: PMC4941640.
      View in: PubMed   Mentions: 210     Fields:    Translation:HumansAnimalsCells
    138. Ribosome profiling reveals the what, when, where and how of protein synthesis. Nat Rev Mol Cell Biol. 2015 Nov; 16(11):651-64. Brar GA, Weissman JS. PMID: 26465719; PMCID: PMC5522010.
      View in: PubMed   Mentions: 242     Fields:    Translation:HumansCells
    139. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 2015 Sep 01; 4:e08153. Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. PMID: 26327694; PMCID: PMC4602331.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    140. Regulation of mRNA translation during mitosis. Elife. 2015 Aug 25; 4. Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD. PMID: 26305499; PMCID: PMC4548207.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    141. Next-generation libraries for robust RNA interference-based genome-wide screens. Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26):E3384-91. Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. PMID: 26080438; PMCID: PMC4491794.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    142. LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". Science. 2015 Jun 12; 348(6240):1217. Jan CH, Williams CC, Weissman JS. PMID: 26068842.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    143. Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3Cβ(D1067V) kinase domain mutation. Oncogene. 2016 Mar 03; 35(9):1198-205. Pazarentzos E, Giannikopoulos P, Hrustanovic G, St John J, Olivas VR, Gubens MA, Balassanian R, Weissman J, Polkinghorn W, Bivona TG. PMID: 25982275.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    144. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 2015 Apr 15; 4:e07314. Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. PMID: 25875391; PMCID: PMC4426669.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansCells
    145. Corrigendum: functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nat Protoc. 2015 Apr; 10(4):643. Kampmann M, Bassik MC, Weissman JS. PMID: 25811902.
      View in: PubMed   Mentions:    Fields:    
    146. Biotechnology. A prudent path forward for genomic engineering and germline gene modification. Science. 2015 Apr 03; 348(6230):36-8. Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, Sternberg SH, Weissman JS, Yamamoto KR. PMID: 25791083; PMCID: PMC4394183.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansCells
    147. Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens. Science. 2015 Mar 06; 347(6226):1259038. Jovanovic M, Rooney MS, Mertins P, Przybylski D, Chevrier N, Satija R, Rodriguez EH, Fields AP, Schwartz S, Raychowdhury R, Mumbach MR, Eisenhaure T, Rabani M, Gennert D, Lu D, Delorey T, Weissman JS, Carr SA, Hacohen N, Regev A. PMID: 25745177; PMCID: PMC4506746.
      View in: PubMed   Mentions: 242     Fields:    Translation:AnimalsCells
    148. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer. Mol Cancer Ther. 2015 Mar; 14(3):642-8. Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. PMID: 25564440; PMCID: PMC4456214.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    149. Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Science. 2015 Jan 02; 347(6217):75-8. Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. PMID: 25554787; PMCID: PMC4451101.
      View in: PubMed   Mentions: 148     Fields:    Translation:AnimalsCells
    150. Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation. Mol Syst Biol. 2014 Dec 23; 10:770. Pop C, Rouskin S, Ingolia NT, Han L, Phizicky EM, Weissman JS, Koller D. PMID: 25538139; PMCID: PMC4300493.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    151. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell. 2015 Jan 15; 160(1-2):339-50. Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA. PMID: 25533786; PMCID: PMC4297522.
      View in: PubMed   Mentions: 408     Fields:    Translation:HumansAnimalsCells
    152. Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 07; 346(6210):748-51. Williams CC, Jan CH, Weissman JS. PMID: 25378625; PMCID: PMC4263316.
      View in: PubMed   Mentions: 169     Fields:    Translation:AnimalsCells
    153. Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 07; 346(6210):1257521. Jan CH, Williams CC, Weissman JS. PMID: 25378630; PMCID: PMC4285348.
      View in: PubMed   Mentions: 205     Fields:    Translation:HumansAnimalsCells
    154. The general mode of translation inhibition by macrolide antibiotics. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):15958-63. Kannan K, Kanabar P, Schryer D, Florin T, Oh E, Bahroos N, Tenson T, Weissman JS, Mankin AS. PMID: 25349425; PMCID: PMC4234590.
      View in: PubMed   Mentions: 84     Fields:    Translation:Cells
    155. Genetic influences on translation in yeast. PLoS Genet. 2014 Oct; 10(10):e1004692. Albert FW, Muzzey D, Weissman JS, Kruglyak L. PMID: 25340754; PMCID: PMC4207643.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    156. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 2014 Oct 23; 159(3):647-61. Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. PMID: 25307932; PMCID: PMC4253859.
      View in: PubMed   Mentions: 1301     Fields:    Translation:HumansCells
    157. A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell. 2014 Oct 23; 159(3):635-46. Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. PMID: 25307933; PMCID: PMC4252608.
      View in: PubMed   Mentions: 662     Fields:    Translation:HumansAnimalsCells
    158. Unraveling the mechanism of cell death induced by chemical fibrils. Nat Chem Biol. 2014 Nov; 10(11):969-76. Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. PMID: 25262416; PMCID: PMC4201873.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    159. Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. Cell Rep. 2014 Sep 11; 8(5):1365-79. Ingolia NT, Brar GA, Stern-Ginossar N, Harris MS, Talhouarne GJ, Jackson SE, Wills MR, Weissman JS. PMID: 25159147; PMCID: PMC4216110.
      View in: PubMed   Mentions: 349     Fields:    Translation:HumansAnimalsCells
    160. Misfolded proteins induce aggregation of the lectin Yos9. J Biol Chem. 2014 Sep 12; 289(37):25670-7. Smith MH, Rodriguez EH, Weissman JS. PMID: 25086047; PMCID: PMC4162170.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    161. The coding and noncoding architecture of the Caulobacter crescentus genome. PLoS Genet. 2014 Jul; 10(7):e1004463. Schrader JM, Zhou B, Li GW, Lasker K, Childers WS, Williams B, Long T, Crosson S, McAdams HH, Weissman JS, Shapiro L. PMID: 25078267; PMCID: PMC4117421.
      View in: PubMed   Mentions: 84     Fields:    Translation:Cells
    162. Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nat Protoc. 2014 Aug; 9(8):1825-47. Kampmann M, Bassik MC, Weissman JS. PMID: 24992097; PMCID: PMC4144868.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    163. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nat Commun. 2014 May 08; 5:3832. van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, Lebbink RJ. PMID: 24807418; PMCID: PMC4024746.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    164. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science. 2014 May 30; 344(6187):1042-7. Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. PMID: 24789973; PMCID: PMC4108260.
      View in: PubMed   Mentions: 180     Fields:    Translation:Cells
    165. Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell. 2014 Apr 24; 157(3):624-35. Li GW, Burkhardt D, Gross C, Weissman JS. PMID: 24766808; PMCID: PMC4006352.
      View in: PubMed   Mentions: 669     Fields:    Translation:AnimalsCells
    166. Extensive and coordinated control of allele-specific expression by both transcription and translation in Candida albicans. Genome Res. 2014 Jun; 24(6):963-73. Muzzey D, Sherlock G, Weissman JS. PMID: 24732588; PMCID: PMC4032860.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    167. Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol. 2014 Mar 31; 204(7):1083-6. Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J. PMID: 24687277; PMCID: PMC3971754.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsCells
    168. Differential scales of protein quality control. Cell. 2014 Mar 27; 157(1):52-64. Wolff S, Weissman JS, Dillin A. PMID: 24679526.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    169. KSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and functional features. PLoS Pathog. 2014 Jan; 10(1):e1003847. Arias C, Weisburd B, Stern-Ginossar N, Mercier A, Madrid AS, Bellare P, Holdorf M, Weissman JS, Ganem D. PMID: 24453964; PMCID: PMC3894221.
      View in: PubMed   Mentions: 198     Fields:    Translation:HumansCells
    170. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell. 2013 Dec 19; 155(7):1479-91. Chen B, Gilbert LA, Cimini BA, Schnitzbauer J, Zhang W, Li GW, Park J, Blackburn EH, Weissman JS, Qi LS, Huang B. PMID: 24360272; PMCID: PMC3918502.
      View in: PubMed   Mentions: 934     Fields:    Translation:HumansCells
    171. Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature. 2014 Jan 30; 505(7485):701-5. Rouskin S, Zubradt M, Washietl S, Kellis M, Weissman JS. PMID: 24336214; PMCID: PMC3966492.
      View in: PubMed   Mentions: 470     Fields:    Translation:HumansAnimalsCells
    172. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Elife. 2013 Dec 03; 2:e01179. Dunn JG, Foo CK, Belletier NG, Gavis ER, Weissman JS. PMID: 24302569; PMCID: PMC3840789.
      View in: PubMed   Mentions: 204     Fields:    Translation:HumansAnimalsCells
    173. Msn2 coordinates a stoichiometric gene expression program. Curr Biol. 2013 Dec 02; 23(23):2336-45. Stewart-Ornstein J, Nelson C, DeRisi J, Weissman JS, El-Samad H. PMID: 24210615; PMCID: PMC4072881.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    174. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chem Biol. 2013 Nov 21; 20(11):1352-63. Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. PMID: 24183972; PMCID: PMC3881547.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    175. Global cellular response to chemotherapy-induced apoptosis. Elife. 2013 Oct 29; 2:e01236. Wiita AP, Ziv E, Wiita PJ, Urisman A, Julien O, Burlingame AL, Weissman JS, Wells JA. PMID: 24171104; PMCID: PMC3808542.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    176. Selective ribosome profiling as a tool for studying the interaction of chaperones and targeting factors with nascent polypeptide chains and ribosomes. Nat Protoc. 2013 Nov; 8(11):2212-39. Becker AH, Oh E, Weissman JS, Kramer G, Bukau B. PMID: 24136347; PMCID: PMC4001812.
      View in: PubMed   Mentions: 61     Fields:    Translation:Cells
    177. CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nat Protoc. 2013 Nov; 8(11):2180-96. Larson MH, Gilbert LA, Wang X, Lim WA, Weissman JS, Qi LS. PMID: 24136345; PMCID: PMC3922765.
      View in: PubMed   Mentions: 516     Fields:    Translation:Cells
    178. A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern. Genes Dev. 2013 Oct 01; 27(19):2147-63. Berchowitz LE, Gajadhar AS, van Werven FJ, De Rosa AA, Samoylova ML, Brar GA, Xu Y, Xiao C, Futcher B, Weissman JS, White FM, Amon A. PMID: 24115771; PMCID: PMC3850098.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    179. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell. 2013 Jul 18; 154(2):442-51. Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS. PMID: 23849981; PMCID: PMC3770145.
      View in: PubMed   Mentions: 1702     Fields:    Translation:HumansAnimalsCells
    180. Genome-wide annotation and quantitation of translation by ribosome profiling. Curr Protoc Mol Biol. 2013 Jul; Chapter 4:4.18.1-4.18.19. Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. PMID: 23821443; PMCID: PMC3775365.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    181. Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. Cell. 2013 Jul 03; 154(1):240-51. Guttman M, Russell P, Ingolia NT, Weissman JS, Lander ES. PMID: 23810193; PMCID: PMC3756563.
      View in: PubMed   Mentions: 403     Fields:    Translation:AnimalsCells
    182. Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):E2317-26. Kampmann M, Bassik MC, Weissman JS. PMID: 23739767; PMCID: PMC3690882.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    183. rRNA:mRNA pairing alters the length and the symmetry of mRNA-protected fragments in ribosome profiling experiments. Bioinformatics. 2013 Jun 15; 29(12):1488-91. O'Connor PB, Li GW, Weissman JS, Atkins JF, Baranov PV. PMID: 23603333; PMCID: PMC3673220.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    184. Aneuploid yeast strains exhibit defects in cell growth and passage through START. Mol Biol Cell. 2013 May; 24(9):1274-89. Thorburn RR, Gonzalez C, Brar GA, Christen S, Carlile TM, Ingolia NT, Sauer U, Weissman JS, Amon A. PMID: 23468524; PMCID: PMC3639041.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    185. The contribution of systematic approaches to characterizing the proteins and functions of the endoplasmic reticulum. Cold Spring Harb Perspect Biol. 2013 Mar 01; 5(3):a013284. Schuldiner M, Weissman JS. PMID: 23359093; PMCID: PMC3578357.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    186. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell. 2013 Feb 28; 152(5):1173-83. Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. PMID: 23452860; PMCID: PMC3664290.
      View in: PubMed   Mentions: 2171     Fields:    Translation:Cells
    187. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 2013 Feb 14; 152(4):909-22. Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. PMID: 23394947; PMCID: PMC3652613.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansCells
    188. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biol. 2013; 14(9):R97. Muzzey D, Schwartz K, Weissman JS, Sherlock G. PMID: 24025428; PMCID: PMC4054093.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    189. Decoding human cytomegalovirus. Science. 2012 Nov 23; 338(6110):1088-93. Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein MY, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman JS. PMID: 23180859; PMCID: PMC3817102.
      View in: PubMed   Mentions: 364     Fields:    Translation:HumansCells
    190. A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress. Cell. 2012 Nov 21; 151(5):1042-54. Brandman O, Stewart-Ornstein J, Wong D, Larson A, Williams CC, Li GW, Zhou S, King D, Shen PS, Weibezahn J, Dunn JG, Rouskin S, Inada T, Frost A, Weissman JS. PMID: 23178123; PMCID: PMC3534965.
      View in: PubMed   Mentions: 350     Fields:    Translation:AnimalsCells
    191. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nat Protoc. 2012 Jul 26; 7(8):1534-50. Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. PMID: 22836135; PMCID: PMC3535016.
      View in: PubMed   Mentions: 688     Fields:    Translation:HumansAnimalsCells
    192. Proto-genes and de novo gene birth. Nature. 2012 Jul 19; 487(7407):370-4. Carvunis AR, Rolland T, Wapinski I, Calderwood MA, Yildirim MA, Simonis N, Charloteaux B, Hidalgo CA, Barbette J, Santhanam B, Brar GA, Weissman JS, Regev A, Thierry-Mieg N, Cusick ME, Vidal M. PMID: 22722833; PMCID: PMC3401362.
      View in: PubMed   Mentions: 339     Fields:    Translation:AnimalsCells
    193. Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell. 2012 Jun 08; 149(6):1339-52. Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein MY, Poser I, Mann M, Hyman AA, Weissman JS. PMID: 22682253; PMCID: PMC3613983.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    194. Special issue: the molecular and cellular mechanisms of amyloidosis. J Mol Biol. 2012 Aug 10; 421(2-3):139-41. Radford SE, Weissman JS. PMID: 22664198.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    195. Native elongating transcript sequencing (NET-seq). Curr Protoc Mol Biol. 2012 Apr; Chapter 4:Unit 4.14.1-17. Churchman LS, Weissman JS. PMID: 22470065.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    196. The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria. Nature. 2012 Mar 28; 484(7395):538-41. Li GW, Oh E, Weissman JS. PMID: 22456704; PMCID: PMC3338875.
      View in: PubMed   Mentions: 341     Fields:    Translation:Cells
    197. Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae. Mol Cell. 2012 Feb 24; 45(4):483-93. Stewart-Ornstein J, Weissman JS, El-Samad H. PMID: 22365828; PMCID: PMC3327736.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    198. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 2012 Feb 22; 485(7396):55-61. Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, Weissman JS, Shokat KM, Rommel C, Ruggero D. PMID: 22367541; PMCID: PMC3663483.
      View in: PubMed   Mentions: 736     Fields:    Translation:HumansAnimalsCells
    199. High-resolution view of the yeast meiotic program revealed by ribosome profiling. Science. 2012 Feb 03; 335(6068):552-7. Brar GA, Yassour M, Friedman N, Regev A, Ingolia NT, Weissman JS. PMID: 22194413; PMCID: PMC3414261.
      View in: PubMed   Mentions: 342     Fields:    Translation:AnimalsCells
    200. Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo. Cell. 2011 Dec 09; 147(6):1295-308. Oh E, Becker AH, Sandikci A, Huber D, Chaba R, Gloge F, Nichols RJ, Typas A, Gross CA, Kramer G, Weissman JS, Bukau B. PMID: 22153074; PMCID: PMC3277850.
      View in: PubMed   Mentions: 240     Fields:    Translation:Cells
    201. Genetics: Noise rules. Nature. 2011 Dec 07; 480(7376):188-9. El-Samad H, Weissman JS. PMID: 22158239.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    202. Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science. 2011 Nov 25; 334(6059):1086-90. Smith MH, Ploegh HL, Weissman JS. PMID: 22116878; PMCID: PMC3864754.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansAnimalsCells
    203. Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19222-7. Roelants FM, Breslow DK, Muir A, Weissman JS, Thorner J. PMID: 22080611; PMCID: PMC3228448.
      View in: PubMed   Mentions: 159     Fields:    Translation:AnimalsCells
    204. Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell. 2011 Nov 11; 147(4):789-802. Ingolia NT, Lareau LF, Weissman JS. PMID: 22056041; PMCID: PMC3225288.
      View in: PubMed   Mentions: 1197     Fields:    Translation:AnimalsCells
    205. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol. 2011 Oct 17; 195(2):323-40. Hoppins S, Collins SR, Cassidy-Stone A, Hummel E, Devay RM, Lackner LL, Westermann B, Schuldiner M, Weissman JS, Nunnari J. PMID: 21987634; PMCID: PMC3198156.
      View in: PubMed   Mentions: 212     Fields:    Translation:AnimalsCells
    206. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature. 2011 Aug 03; 476(7358):88-91. Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D. PMID: 21814281; PMCID: PMC3535012.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    207. H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway. Mol Cell Biol. 2011 Sep; 31(17):3569-83. Terzi N, Churchman LS, Vasiljeva L, Weissman J, Buratowski S. PMID: 21709022; PMCID: PMC3165552.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    208. Strain conformation, primary structure and the propagation of the yeast prion [PSI+]. Nat Struct Mol Biol. 2011 Apr; 18(4):493-9. Verges KJ, Smith MH, Toyama BH, Weissman JS. PMID: 21423194; PMCID: PMC3490428.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    209. Radically different amyloid conformations dictate the seeding specificity of a chimeric Sup35 prion. J Mol Biol. 2011 Apr 22; 408(1):1-8. Foo CK, Ohhashi Y, Kelly MJ, Tanaka M, Weissman JS. PMID: 21333653; PMCID: PMC3070826.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    210. Nascent transcript sequencing visualizes transcription at nucleotide resolution. Nature. 2011 Jan 20; 469(7330):368-73. Churchman LS, Weissman JS. PMID: 21248844; PMCID: PMC3880149.
      View in: PubMed   Mentions: 477     Fields:    Translation:AnimalsCells
    211. Amyloid structure: conformational diversity and consequences. Annu Rev Biochem. 2011; 80:557-85. Toyama BH, Weissman JS. PMID: 21456964; PMCID: PMC3817101.
      View in: PubMed   Mentions: 113     Fields:    Translation:Cells
    212. Systematic screen of Schizosaccharomyces pombe deletion collection uncovers parallel evolution of the phosphate signal transduction pathway in yeasts. Eukaryot Cell. 2011 Feb; 10(2):198-206. Henry TC, Power JE, Kerwin CL, Mohammed A, Weissman JS, Cameron DM, Wykoff DD. PMID: 21169418; PMCID: PMC3067400.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    213. The epistemology of cell biology. Mol Biol Cell. 2010 Nov 15; 21(22):3825. Weissman JS. PMID: 21079033; PMCID: PMC2982092.
      View in: PubMed   Mentions: 1     Fields:    
    214. Membranes in balance: mechanisms of sphingolipid homeostasis. Mol Cell. 2010 Oct 22; 40(2):267-79. Breslow DK, Weissman JS. PMID: 20965421; PMCID: PMC2987644.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    215. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 2010 Aug 12; 466(7308):835-40. Guo H, Ingolia NT, Weissman JS, Bartel DP. PMID: 20703300; PMCID: PMC2990499.
      View in: PubMed   Mentions: 2098     Fields:    Translation:HumansAnimalsCells
    216. Automated identification of pathways from quantitative genetic interaction data. Mol Syst Biol. 2010 Jun 08; 6:379. Battle A, Jonikas MC, Walter P, Weissman JS, Koller D. PMID: 20531408; PMCID: PMC2913392.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    217. A general lack of compensation for gene dosage in yeast. Mol Syst Biol. 2010 May 11; 6:368. Springer M, Weissman JS, Kirschner MW. PMID: 20461075; PMCID: PMC2890323.
      View in: PubMed   Mentions: 78     Fields:    Translation:Animals
    218. J domain co-chaperone specificity defines the role of BiP during protein translocation. J Biol Chem. 2010 Jul 16; 285(29):22484-94. Vembar SS, Jonikas MC, Hendershot LM, Weissman JS, Brodsky JL. PMID: 20430885; PMCID: PMC2903355.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    219. Molecular basis of infrared detection by snakes. Nature. 2010 Apr 15; 464(7291):1006-11. Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D. PMID: 20228791; PMCID: PMC2855400.
      View in: PubMed   Mentions: 172     Fields:    Translation:AnimalsCells
    220. Orm family proteins mediate sphingolipid homeostasis. Nature. 2010 Feb 25; 463(7284):1048-53. Breslow DK, Collins SR, Bodenmiller B, Aebersold R, Simons K, Shevchenko A, Ejsing CS, Weissman JS. PMID: 20182505; PMCID: PMC2877384.
      View in: PubMed   Mentions: 310     Fields:    Translation:HumansAnimalsCells
    221. Differences in prion strain conformations result from non-native interactions in a nucleus. Nat Chem Biol. 2010 Mar; 6(3):225-230. Ohhashi Y, Ito K, Toyama BH, Weissman JS, Tanaka M. PMID: 20081853; PMCID: PMC3277852.
      View in: PubMed   Mentions: 41     Fields:    
    222. Journal club. A biochemist looks at how DNA sequencing can reveal more than just sequences. Nature. 2009 Oct 29; 461(7268):1177. Weissman J. PMID: 19865125.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    223. From information to knowledge: new technologies for defining gene function. Nat Methods. 2009 Oct; 6(10):721-23. Collins SR, Weissman JS, Krogan NJ. PMID: 19953683; PMCID: PMC3066030.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    224. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol. 2009 Aug 10; 186(3):323-31. Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. PMID: 19651891; PMCID: PMC2728407.
      View in: PubMed   Mentions: 529     Fields:    Translation:AnimalsCells
    225. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science. 2009 Jul 24; 325(5939):477-81. Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P. PMID: 19556461; PMCID: PMC2933203.
      View in: PubMed   Mentions: 632     Fields:    Translation:AnimalsCells
    226. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat Methods. 2009 Jun; 6(6):443-5. Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. PMID: 19448642; PMCID: PMC2783737.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    227. Analysis of Dom34 and its function in no-go decay. Mol Biol Cell. 2009 Jul; 20(13):3025-32. Passos DO, Doma MK, Shoemaker CJ, Muhlrad D, Green R, Weissman J, Hollien J, Parker R. PMID: 19420139; PMCID: PMC2704154.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    228. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009 Mar 27; 323(5922):1693-7. Jonikas MC, Collins SR, Denic V, Oh E, Quan EM, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman JS, Schuldiner M. PMID: 19325107; PMCID: PMC2877488.
      View in: PubMed   Mentions: 400     Fields:    Translation:AnimalsCells
    229. Functional organization of the S. cerevisiae phosphorylation network. Cell. 2009 Mar 06; 136(5):952-63. Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, Shokat KM, Krogan NJ. PMID: 19269370; PMCID: PMC2856666.
      View in: PubMed   Mentions: 165     Fields:    Translation:AnimalsCells
    230. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science. 2009 Apr 10; 324(5924):218-23. Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. PMID: 19213877; PMCID: PMC2746483.
      View in: PubMed   Mentions: 2042     Fields:    Translation:AnimalsCells
    231. Defining the glycan destruction signal for endoplasmic reticulum-associated degradation. Mol Cell. 2008 Dec 26; 32(6):870-7. Quan EM, Kamiya Y, Kamiya D, Denic V, Weibezahn J, Kato K, Weissman JS. PMID: 19111666; PMCID: PMC2873636.
      View in: PubMed   Mentions: 114     Fields:    Translation:AnimalsCells
    232. A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell. 2008 Dec 05; 32(5):735-46. Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ. PMID: 19061648; PMCID: PMC2644724.
      View in: PubMed   Mentions: 162     Fields:    Translation:AnimalsCells
    233. In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104. Mol Cell. 2008 Nov 21; 32(4):584-91. Tipton KA, Verges KJ, Weissman JS. PMID: 19026788; PMCID: PMC2875781.
      View in: PubMed   Mentions: 120     Fields:    Translation:AnimalsCells
    234. Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network. Nat Biotechnol. 2008 Nov; 26(11):1251-9. Chechik G, Oh E, Rando O, Weissman J, Regev A, Koller D. PMID: 18953355; PMCID: PMC2651818.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    235. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Science. 2008 Oct 17; 322(5900):405-10. Roguev A, Bandyopadhyay S, Zofall M, Zhang K, Fischer T, Collins SR, Qu H, Shales M, Park HO, Hayles J, Hoe KL, Kim DU, Ideker T, Grewal SI, Weissman JS, Krogan NJ. PMID: 18818364; PMCID: PMC2753251.
      View in: PubMed   Mentions: 212     Fields:    Translation:AnimalsCells
    236. High-throughput, quantitative analyses of genetic interactions in E. coli. Nat Methods. 2008 Sep; 5(9):781-7. Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. PMID: 19160513; PMCID: PMC2700713.
      View in: PubMed   Mentions: 139     Fields:    Translation:Cells
    237. Systems biology: Reverse engineering the cell. Nature. 2008 Aug 28; 454(7208):1059-62. Ingolia NT, Weissman JS. PMID: 18756243.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    238. The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell. 2008 Aug 22; 134(4):634-45. Schuldiner M, Metz J, Schmid V, Denic V, Rakwalska M, Schmitt HD, Schwappach B, Weissman JS. PMID: 18724936; PMCID: PMC2572727.
      View in: PubMed   Mentions: 279     Fields:    Translation:AnimalsCells
    239. A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods. 2008 Aug; 5(8):711-8. Breslow DK, Cameron DM, Collins SR, Schuldiner M, Stewart-Ornstein J, Newman HW, Braun S, Madhani HD, Krogan NJ, Weissman JS. PMID: 18622397; PMCID: PMC2756093.
      View in: PubMed   Mentions: 305     Fields:    Translation:Animals
    240. Small-molecule aggregates inhibit amyloid polymerization. Nat Chem Biol. 2008 Mar; 4(3):197-9. Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. PMID: 18223646; PMCID: PMC2730835.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    241. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18079-84. Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. PMID: 17989219; PMCID: PMC2084299.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    242. High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe. Nat Methods. 2007 Oct; 4(10):861-6. Roguev A, Wiren M, Weissman JS, Krogan NJ. PMID: 17893680.
      View in: PubMed   Mentions: 98     Fields:    Translation:Animals
    243. The structural basis of yeast prion strain variants. Nature. 2007 Sep 13; 449(7159):233-7. Toyama BH, Kelly MJ, Gross JD, Weissman JS. PMID: 17767153.
      View in: PubMed   Mentions: 198     Fields:    Translation:AnimalsCells
    244. A molecular caliper mechanism for determining very long-chain fatty acid length. Cell. 2007 Aug 24; 130(4):663-77. Denic V, Weissman JS. PMID: 17719544.
      View in: PubMed   Mentions: 115     Fields:    Translation:Cells
    245. Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell. 2007 Aug 10; 130(3):499-511. Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X. PMID: 17693258.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    246. Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss. Mol Syst Biol. 2007; 3:86. Ihmels J, Collins SR, Schuldiner M, Krogan NJ, Weissman JS. PMID: 17389874; PMCID: PMC1847942.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    247. CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):5836-41. Laribee RN, Shibata Y, Mersman DP, Collins SR, Kemmeren P, Roguev A, Weissman JS, Briggs SD, Krogan NJ, Strahl BD. PMID: 17389396; PMCID: PMC1851578.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    248. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature. 2007 Apr 12; 446(7137):806-10. Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, Andrews B, Boone C, Berger SL, Hieter P, Zhang Z, Brown GW, Ingles CJ, Emili A, Allis CD, Toczyski DP, Weissman JS, Greenblatt JF, Krogan NJ. PMID: 17314980.
      View in: PubMed   Mentions: 541     Fields:    Translation:AnimalsCells
    249. Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Mol Cell Proteomics. 2007 Mar; 6(3):439-50. Collins SR, Kemmeren P, Zhao XC, Greenblatt JF, Spencer F, Holstege FC, Weissman JS, Krogan NJ. PMID: 17200106.
      View in: PubMed   Mentions: 352     Fields:    Translation:Animals
    250. Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. Methods. 2006 Dec; 40(4):344-52. Schuldiner M, Collins SR, Weissman JS, Krogan NJ. PMID: 17101447.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    251. Systems biology: many things from one. Nature. 2006 Nov 30; 444(7119):561-2. Newman JR, Weissman JS. PMID: 17122769.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    252. A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation. Cell. 2006 Jul 28; 126(2):349-59. Denic V, Quan EM, Weissman JS. PMID: 16873065.
      View in: PubMed   Mentions: 216     Fields:    Translation:AnimalsCells
    253. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science. 2006 Jul 07; 313(5783):104-7. Hollien J, Weissman JS. PMID: 16825573.
      View in: PubMed   Mentions: 665     Fields:    Translation:AnimalsCells
    254. The physical basis of how prion conformations determine strain phenotypes. Nature. 2006 Aug 03; 442(7102):585-9. Tanaka M, Collins SR, Toyama BH, Weissman JS. PMID: 16810177.
      View in: PubMed   Mentions: 316     Fields:    Translation:AnimalsCells
    255. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature. 2006 Jun 15; 441(7095):840-6. Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. PMID: 16699522.
      View in: PubMed   Mentions: 740     Fields:    Translation:Animals
    256. Molecular chaperones and protein quality control. Cell. 2006 May 05; 125(3):443-51. Bukau B, Weissman J, Horwich A. PMID: 16678092.
      View in: PubMed   Mentions: 661     Fields:    Translation:HumansAnimalsCells
    257. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30; 440(7084):637-43. Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O'Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF. PMID: 16554755.
      View in: PubMed   Mentions: 1259     Fields:    Translation:AnimalsCells
    258. A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biol. 2006; 7(7):R63. Collins SR, Schuldiner M, Krogan NJ, Weissman JS. PMID: 16859555; PMCID: PMC1779568.
      View in: PubMed   Mentions: 190     Fields:    
    259. An efficient protein transformation protocol for introducing prions into yeast. Methods Enzymol. 2006; 412:185-200. Tanaka M, Weissman JS. PMID: 17046659.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    260. Domain architecture of protein-disulfide isomerase facilitates its dual role as an oxidase and an isomerase in Ero1p-mediated disulfide formation. J Biol Chem. 2006 Jan 13; 281(2):876-84. Kulp MS, Frickel EM, Ellgaard L, Weissman JS. PMID: 16368681.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    261. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell. 2005 Nov 18; 123(4):593-605. Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, Grunstein M, Greenblatt JF, Buratowski S, Krogan NJ. PMID: 16286008.
      View in: PubMed   Mentions: 481     Fields:    Translation:AnimalsCells
    262. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell. 2005 Nov 04; 123(3):507-19. Schuldiner M, Collins SR, Thompson NJ, Denic V, Bhamidipati A, Punna T, Ihmels J, Andrews B, Boone C, Greenblatt JF, Weissman JS, Krogan NJ. PMID: 16269340.
      View in: PubMed   Mentions: 483     Fields:    Translation:AnimalsCells
    263. Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen. Mol Cell. 2005 Sep 16; 19(6):741-51. Bhamidipati A, Denic V, Quan EM, Weissman JS. PMID: 16168370.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    264. Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins. Cell. 2005 Apr 08; 121(1):49-62. Tanaka M, Chien P, Yonekura K, Weissman JS. PMID: 15820678.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    265. Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. Comp Funct Genomics. 2005; 6(1-2):2-16. Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK. PMID: 18629296; PMCID: PMC2448600.
      View in: PubMed   Mentions: 43  
    266. 2004 Irving Sigal Young Investigator Award. Protein Sci. 2004 Dec; 13(12):3333-5. Weissman JS, O'Shea EK. PMID: 15557272; PMCID: PMC2287319.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    267. Mechanism of prion propagation: amyloid growth occurs by monomer addition. PLoS Biol. 2004 Oct; 2(10):e321. Collins SR, Douglass A, Vale RD, Weissman JS. PMID: 15383837; PMCID: PMC517824.
      View in: PubMed   Mentions: 205     Fields:    
    268. Dissection and design of yeast prions. PLoS Biol. 2004 Apr; 2(4):E86. Osherovich LZ, Cox BS, Tuite MF, Weissman JS. PMID: 15045026; PMCID: PMC374241.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    269. Conformational variations in an infectious protein determine prion strain differences. Nature. 2004 Mar 18; 428(6980):323-8. Tanaka M, Chien P, Naber N, Cooke R, Weissman JS. PMID: 15029196.
      View in: PubMed   Mentions: 391     Fields:    Translation:AnimalsCells
    270. Oxidative protein folding in eukaryotes: mechanisms and consequences. J Cell Biol. 2004 Feb 02; 164(3):341-6. Tu BP, Weissman JS. PMID: 14757749; PMCID: PMC2172237.
      View in: PubMed   Mentions: 400     Fields:    Translation:HumansAnimalsCells
    271. Emerging principles of conformation-based prion inheritance. Annu Rev Biochem. 2004; 73:617-56. Chien P, Weissman JS, DePace AH. PMID: 15189155.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    272. Global analysis of protein expression in yeast. Nature. 2003 Oct 16; 425(6959):737-41. Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. PMID: 14562106.
      View in: PubMed   Mentions: 1892     Fields:    Translation:Animals
    273. Global analysis of protein localization in budding yeast. Nature. 2003 Oct 16; 425(6959):686-91. Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. PMID: 14562095.
      View in: PubMed   Mentions: 2054     Fields:    Translation:AnimalsCells
    274. Generation of prion transmission barriers by mutational control of amyloid conformations. Nature. 2003 Aug 21; 424(6951):948-51. Chien P, DePace AH, Collins SR, Weissman JS. PMID: 12931190.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    275. Directed evolution of substrate-optimized GroEL/S chaperonins. Cell. 2002 Dec 27; 111(7):1027-39. Wang JD, Herman C, Tipton KA, Gross CA, Weissman JS. PMID: 12507429.
      View in: PubMed   Mentions: 62     Fields:    Translation:Cells
    276. The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum. Mol Cell. 2002 Nov; 10(5):983-94. Tu BP, Weissman JS. PMID: 12453408.
      View in: PubMed   Mentions: 153     Fields:    Translation:AnimalsCells
    277. Origins and kinetic consequences of diversity in Sup35 yeast prion fibers. Nat Struct Biol. 2002 May; 9(5):389-96. DePace AH, Weissman JS. PMID: 11938354.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    278. The utility of prions. Dev Cell. 2002 Feb; 2(2):143-51. Osherovich LZ, Weissman JS. PMID: 11832240.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    279. Prion diseases. A rogue protein. Lancet. 2001 Dec; 358 Suppl:S53. Weissman JS, Hood JK. PMID: 11784602.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    280. The ins and outs of GroEL-mediated protein folding. Mol Cell. 2001 Oct; 8(4):730-2. Weissman JS. PMID: 11684006.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    281. Preparedness for clinical practice: reports of graduating residents at academic health centers. JAMA. 2001 Sep 05; 286(9):1027-34. Blumenthal D, Gokhale M, Campbell EG, Weissman JS. PMID: 11559286.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    282. Racial differences in cardiac revascularization rates: does "overuse" explain higher rates among white patients? Ann Intern Med. 2001 Sep 04; 135(5):328-37. Schneider EC, Leape LL, Weissman JS, Piana RN, Gatsonis C, Epstein AM. PMID: 11529696.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    283. Residents' preferences and preparation for caring for underserved populations. J Urban Health. 2001 Sep; 78(3):535-49. Weissman JS, Campbell EG, Gokhale M, Blumenthal D. PMID: 11564855; PMCID: PMC3455908.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    284. The relationship of market forces to the satisfaction of faculty at academic health centers. Am J Med. 2001 Sep; 111(4):333-40. Blumenthal D, Causino N, Campbell EG, Weissman JS. PMID: 11566469.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    285. Status of clinical research in academic health centers: views from the research leadership. JAMA. 2001 Aug 15; 286(7):800-6. Campbell EG, Weissman JS, Moy E, Blumenthal D. PMID: 11497533.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    286. Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion. Cell. 2001 Jul 27; 106(2):183-94. Osherovich LZ, Weissman JS. PMID: 11511346.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimalsCells
    287. Conformational diversity in a yeast prion dictates its seeding specificity. Nature. 2001 Mar 08; 410(6825):223-7. Chien P, Weissman JS. PMID: 11242084.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    288. The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. J Cell Biol. 2001 Jan 08; 152(1):213-29. Aridor M, Fish KN, Bannykh S, Weissman J, Roberts TH, Lippincott-Schwartz J, Balch WE. PMID: 11149932; PMCID: PMC2193666.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    289. Functional genomic approaches to understanding molecular chaperones and stress responses. Adv Protein Chem. 2001; 59:345-90. Travers KJ, Patil CK, Weissman JS. PMID: 11868277.
      View in: PubMed   Mentions: 4     Fields:    
    290. The action of molecular chaperones in the early secretory pathway. Annu Rev Genet. 2001; 35:149-91. Fewell SW, Travers KJ, Weissman JS, Brodsky JL. PMID: 11700281.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    291. Understanding the relationship between market competition and students' ratings of the managed care content of their undergraduate medical education. Acad Med. 2001 Jan; 76(1):51-9. Campbell EG, Weissman JS, Ausiello J, Wyatt S, Blumenthal D. PMID: 11154197.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    292. Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science. 2000 Nov 24; 290(5496):1571-4. Tu BP, Ho-Schleyer SC, Travers KJ, Weissman JS. PMID: 11090354.
      View in: PubMed   Mentions: 159     Fields:    Translation:AnimalsCells
    293. Racial disparities in access to renal transplantation--clinically appropriate or due to underuse or overuse? N Engl J Med. 2000 Nov 23; 343(21):1537-44, 2 p preceding 1537. Epstein AM, Ayanian JZ, Keogh JH, Noonan SJ, Armistead N, Cleary PD, Weissman JS, David-Kasdan JA, Carlson D, Fuller J, Marsh D, Conti RM. PMID: 11087884; PMCID: PMC4598055.
      View in: PubMed   Mentions: 166     Fields:    Translation:Humans
    294. Unmet health needs of uninsured adults in the United States. JAMA. 2000 Oct 25; 284(16):2061-9. Ayanian JZ, Weissman JS, Schneider EC, Ginsburg JA, Zaslavsky AM. PMID: 11042754.
      View in: PubMed   Mentions: 245     Fields:    Translation:HumansPHPublic Health
    295. A census of glutamine/asparagine-rich regions: implications for their conserved function and the prediction of novel prions. Proc Natl Acad Sci U S A. 2000 Oct 24; 97(22):11910-5. Michelitsch MD, Weissman JS. PMID: 11050225; PMCID: PMC17268.
      View in: PubMed   Mentions: 258     Fields:    Translation:HumansCells
    296. Evidence for the prion hypothesis: induction of the yeast [PSI+] factor by in vitro- converted Sup35 protein. Science. 2000 Jul 28; 289(5479):595-9. Sparrer HE, Santoso A, Szoka FC, Weissman JS. PMID: 10915616.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    297. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell. 2000 Apr 28; 101(3):249-58. Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, Walter P. PMID: 10847680.
      View in: PubMed   Mentions: 853     Fields:    Translation:AnimalsCells
    298. Stage-specific assays to study biosynthetic cargo selection and role of SNAREs in export from the endoplasmic reticulum and delivery to the Golgi. Methods. 2000 Apr; 20(4):411-6. Allan BB, Weissman J, Aridor M, Moyer B, Chen CD, Yoo JS, Balch WE. PMID: 10720462.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    299. Molecular basis of a yeast prion species barrier. Cell. 2000 Jan 21; 100(2):277-88. Santoso A, Chien P, Osherovich LZ, Weissman JS. PMID: 10660050.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    300. Quality of care by race and gender for congestive heart failure and pneumonia. Med Care. 1999 Dec; 37(12):1260-9. Ayanian JZ, Weissman JS, Chasan-Taber S, Epstein AM. PMID: 10599607.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    301. The effect of patients' preferences on racial differences in access to renal transplantation. N Engl J Med. 1999 Nov 25; 341(22):1661-9. Ayanian JZ, Cleary PD, Weissman JS, Epstein AM. PMID: 10572155.
      View in: PubMed   Mentions: 175     Fields:    Translation:Humans
    302. Academic health centers on the front lines: survival strategies in highly competitive markets. Acad Med. 1999 Sep; 74(9):1038-49. Blumenthal D, Weissman JS, Griner PF. PMID: 10498101.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    303. Thinking outside the box: new insights into the mechanism of GroEL-mediated protein folding. Nat Struct Biol. 1999 Jul; 6(7):597-600. Wang JD, Weissman JS. PMID: 10404205.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    304. Hospital readmissions and quality of care. Med Care. 1999 May; 37(5):490-501. Weissman JS, Ayanian JZ, Chasan-Taber S, Sherwood MJ, Roth C, Epstein AM. PMID: 10335751.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    305. Market forces and unsponsored research in academic health centers. JAMA. 1999 Mar 24-31; 281(12):1093-8. Weissman JS, Saglam D, Campbell EG, Causino N, Blumenthal D. PMID: 10188659.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    306. Termination from Medicaid: how does it affect access, continuity of care, and willingness to purchase insurance? J Health Care Poor Underserved. 1999 Feb; 10(1):122-37. Weissman JS, Witzburg R, Linov P, Campbell EG. PMID: 9989010.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    307. The stability of preferences for life-sustaining care among persons with AIDS in the Boston Health Study. Med Decis Making. 1999 Jan-Mar; 19(1):16-26. Weissman JS, Haas JS, Fowler FJ, Gatsonis C, Massagli MP, Seage GR, Cleary P. PMID: 9917016.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    308. GroEL-GroES-mediated protein folding requires an intact central cavity. Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21):12163-8. Wang JD, Michelitsch MD, Weissman JS. PMID: 9770457; PMCID: PMC22802.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    309. A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion. Cell. 1998 Jun 26; 93(7):1241-52. DePace AH, Santoso A, Hillner P, Weissman JS. PMID: 9657156.
      View in: PubMed   Mentions: 166     Fields:    Translation:AnimalsCells
    310. Costs and outcomes of AIDS care: comparing a health maintenance organization with fee-for-service systems in the Boston Health Study. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Apr 15; 17(5):424-32. Wilson IB, Sullivan LM, Weissman JS. PMID: 9562045.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    311. Cargo selection by the COPII budding machinery during export from the ER. J Cell Biol. 1998 Apr 06; 141(1):61-70. Aridor M, Weissman J, Bannykh S, Nuoffer C, Balch WE. PMID: 9531548; PMCID: PMC2132735.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    312. Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum. Mol Cell. 1998 Jan; 1(2):171-82. Pollard MG, Travers KJ, Weissman JS. PMID: 9659914.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansAnimalsCells
    313. Construction of single-ring and two-ring hybrid versions of bacterial chaperonin GroEL. Methods Enzymol. 1998; 290:141-6. Horwich AL, Burston SG, Rye HS, Weissman JS, Fenton WA. PMID: 9534157.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    314. Commentary: economic transfers, the changing face of a familiar problem. Health Serv Res. 1997 Dec; 32(5):591-8. Weissman JS. PMID: 9402902; PMCID: PMC1070216.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    315. Deadly conformations--protein misfolding in prion disease. Cell. 1997 May 16; 89(4):499-510. Horwich AL, Weissman JS. PMID: 9160742.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    316. The influence of health-related quality of life and social characteristics on hospital use by patients with AIDS in the Boston Health Study. Med Care. 1996 Oct; 34(10):1037-56. Weissman JS, Cleary PD, Seage GR, Gatsonis C, Haas JS, Chasan-Taber S, Epstein AM. PMID: 8843929.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    317. Uncompensated hospital care. Will it be there if we need it? JAMA. 1996 Sep 11; 276(10):823-8. Weissman J. PMID: 8769594.
      View in: PubMed   Mentions: 6     Fields:    
    318. Release of both native and non-native proteins from a cis-only GroEL ternary complex. Nature. 1996 Sep 05; 383(6595):96-9. Burston SG, Weissman JS, Farr GW, Fenton WA, Horwich AL. PMID: 8779722.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    319. The validity of self-reported health-care utilization by AIDS patients. AIDS. 1996 Jun; 10(7):775-83. Weissman JS, Levin K, Chasan-Taber S, Massagli MP, Seage GR, Scampini L. PMID: 8805870.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    320. Putting a lid on protein folding: structure and function of the co-chaperonin, GroES. Chem Biol. 1996 Mar; 3(3):157-61. Fenton WA, Weissman JS, Horwich AL. PMID: 8807841.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    321. Characterization of the active intermediate of a GroEL-GroES-mediated protein folding reaction. Cell. 1996 Feb 09; 84(3):481-90. Weissman JS, Rye HS, Fenton WA, Beechem JM, Horwich AL. PMID: 8608602.
      View in: PubMed   Mentions: 116     Fields:    Translation:AnimalsCells
    322. A kinetic explanation for the rearrangement pathway of BPTI folding. Nat Struct Biol. 1995 Dec; 2(12):1123-30. Weissman JS, Kim PS. PMID: 8846225.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    323. Mechanism of GroEL action: productive release of polypeptide from a sequestered position under GroES. Cell. 1995 Nov 17; 83(4):577-87. Weissman JS, Hohl CM, Kovalenko O, Kashi Y, Chen S, Braig K, Saibil HR, Fenton WA, Horwich AL. PMID: 7585961.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    324. Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. J Mol Biol. 1995 Jun 02; 249(2):388-97. Yu MH, Weissman JS, Kim PS. PMID: 7540212.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    325. All roads lead to Rome? The multiple pathways of protein folding. Chem Biol. 1995 May; 2(5):255-60. Weissman JS. PMID: 9383427.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    326. From the cradle to the grave: ring complexes in the life of a protein. Science. 1995 Apr 28; 268(5210):523-4. Weissman JS, Sigler PB, Horwich AL. PMID: 7725096.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    327. Costs of medical care and out-of-pocket expenditures for persons with AIDS in the Boston Health Study. Inquiry. 1995; 32(2):211-21. Epstein AM, Seage G, Weissman JS, Cleary PD, Fowler FJ, Gatsonis C, Massagli MP, Stone VE, Coltin K, Craven DE, et al. PMID: 7601519.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    328. Kinesis of polypeptide during GroEL-mediated folding. Cold Spring Harb Symp Quant Biol. 1995; 60:435-40. Horwich AL, Weissman JS, Fenton WA. PMID: 8824417.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    329. GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms. Cell. 1994 Aug 26; 78(4):693-702. Weissman JS, Kashi Y, Fenton WA, Horwich AL. PMID: 7915201.
      View in: PubMed   Mentions: 98     Fields:    Translation:Cells
    330. Heat shock proteins and molecular chaperones: mediators of protein conformation and turnover in the cell. Cell. 1994 Aug 12; 78(3):365-72. Craig EA, Weissman JS, Horwich AL. PMID: 7914834.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    331. Utilization of formal and informal home care by AIDS patients in Boston: a comparison of intravenous drug users and homosexual males. Med Care. 1994 May; 32(5):459-70. Ettner SL, Weissman J. PMID: 8182974.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    332. Physician discretion and racial variation in the use of surgical procedures. Arch Intern Med. 1994 Apr 11; 154(7):761-7. Mort EA, Weissman JS, Epstein AM. PMID: 8147680.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    333. The impact of patient socioeconomic status and other social factors on readmission: a prospective study in four Massachusetts hospitals. Inquiry. 1994; 31(2):163-72. Weissman JS, Stern RS, Epstein AM. PMID: 8021022.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    334. Efficient catalysis of disulphide bond rearrangements by protein disulphide isomerase. Nature. 1993 Sep 09; 365(6442):185-8. Weissman JS, Kim PS. PMID: 7690463.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    335. Health-related quality of life in persons with acquired immune deficiency syndrome. Med Care. 1993 Jul; 31(7):569-80. Cleary PD, Fowler FJ, Weissman J, Massagli MP, Wilson I, Seage GR, Gatsonis C, Epstein A. PMID: 8326772.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    336. The pro region of BPTI facilitates folding. Cell. 1992 Nov 27; 71(5):841-51. Weissman JS, Kim PS. PMID: 1384990.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    337. Rates of avoidable hospitalization by insurance status in Massachusetts and Maryland. JAMA. 1992 Nov 04; 268(17):2388-94. Weissman JS, Gatsonis C, Epstein AM. PMID: 1404795.
      View in: PubMed   Mentions: 190     Fields:    Translation:Humans
    338. Kinetic role of nonnative species in the folding of bovine pancreatic trypsin inhibitor. Proc Natl Acad Sci U S A. 1992 Oct 15; 89(20):9900-4. Weissman JS, Kim PS. PMID: 1384063; PMCID: PMC50241.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    339. The emergency department as a pathway to admission for poor and high-cost patients. JAMA. 1991 Oct 23-30; 266(16):2238-43. Stern RS, Weissman JS, Epstein AM. PMID: 1920722.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    340. Reexamination of the folding of BPTI: predominance of native intermediates. Science. 1991 Sep 20; 253(5026):1386-93. Weissman JS, Kim PS. PMID: 1716783.
      View in: PubMed   Mentions: 117     Fields:    Translation:Cells
    341. Acute aortic thrombosis causing sudden paraplegia in a patient with known thoraco-lumbar spinal metastasis: the diagnostic usefulness of magnetic resonance imaging. Neurosurgery. 1989 Jul; 25(1):105-9. Moore MR, Blatter DD, Weissman J, Tyler HR. PMID: 2755568.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    342. Case mix and resource utilization by uninsured hospital patients in the Boston metropolitan area. JAMA. 1989 Jun 23-30; 261(24):3572-6. Weissman J, Epstein AM. PMID: 2498539.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    343. Risk factors of drug impairment in random samples of physicians and medical students. Int J Addict. 1987 Sep; 22(9):825-41. McAuliffe WE, Santangelo S, Magnuson E, Sobol A, Rohman M, Weissman J. PMID: 3679638.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    344. Metabolism of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by liver homogenate fractions. J Med Chem. 1985 Aug; 28(8):997-1001. Weissman J, Trevor A, Chiba K, Peterson LA, Caldera P, Castagnoli N, Baillie T. PMID: 3874963.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    Jonathan's Networks
    Concepts (1113)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (133)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).

    We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use. This site is running Profiles RNS version UCSF-v3.1.0-9-g3adcefa5 on PROFILES-PWEB03.

    Copyright © The Regents of the University of California.