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Jonathan Weissman, PhD

Title(s)Howard Hughes Investigator, Cellular Molecular Pharmacology
SchoolSchool of Medicine
Address1700 4th St
San Francisco CA 94158
Phone415-502-8089
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    Other Positions
    Title(s)Professor, School of Medicine


    Collapse Research 
    Collapse Research Activities and Funding
    The Cancer Target Discovery and Development Network at UCSF
    NIH/NCI U01CA217882Aug 10, 2017 - Jul 31, 2022
    Role: Co-Principal Investigator
    Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming
    NIH/NIDA R01DA036858Sep 30, 2013 - May 31, 2018
    Role: Principal Investigator
    Structural Basis of Protein Homeostasis
    NIH/NIGMS U01GM098254Sep 30, 2012 - Jul 31, 2015
    Role: Co-Principal Investigator
    Human Gene Knockdowns that May Extend Lifespan
    NIH/NIA R01AG041826May 1, 2012 - Apr 30, 2017
    Role: Principal Investigator
    Bay Area Cancer Target Discovery and Development Network
    NIH/NCI U01CA168370May 1, 2012 - Apr 30, 2017
    Role: Co-Principal Investigator
    MECHANISM OF CHAPERONE MEDIATED PROTEIN FOLDING
    NIH/NIGMS R01GM055595May 1, 1997 - Apr 30, 2002
    Role: Principal Investigator
    Molecular Pathogenesis of Age-Dependent CNS Regeneration
    NIH/NIA P01AG010770Apr 1, 1993 - Mar 31, 2016
    Role: Co-Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway. Curr Biol. 2020 Aug 20. Jiménez-Rojo N, Leonetti MD, Zoni V, Colom A, Feng S, Iyengar NR, Matile S, Roux A, Vanni S, Weissman JS, Riezman H. PMID: 32857977.
      View in: PubMed   Mentions:    Fields:    
    2. Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing. Cell. 2020 Aug 07. Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG. PMID: 32822576.
      View in: PubMed   Mentions:    Fields:    
    3. Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span. Sci Adv. 2020 Aug; 6(32):eaba1306. Zou K, Rouskin S, Dervishi K, McCormick MA, Sasikumar A, Deng C, Chen Z, Kaeberlein M, Brem RB, Polymenis M, Kennedy BK, Weissman JS, Zheng J, Ouyang Q, Li H. PMID: 32821821.
      View in: PubMed   Mentions:    Fields:    
    4. GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control. Mol Cell. 2020 09 17; 79(6):950-962.e6. Hickey KL, Dickson K, Cogan JZ, Replogle JM, Schoof M, D'Orazio KN, Sinha NK, Hussmann JA, Jost M, Frost A, Green R, Weissman JS, Kostova KK. PMID: 32726578.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent. Mol Cell. 2020 07 02; 79(1):191-198.e3. Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. PMID: 32619469.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    6. Polysomes Bypass a 50-Nucleotide Coding Gap Less Efficiently Than Monosomes Due to Attenuation of a 5' mRNA Stem-Loop and Enhanced Drop-off. J Mol Biol. 2020 Jul 24; 432(16):4369-4387. O'Loughlin S, Capece MC, Klimova M, Wills NM, Coakley A, Samatova E, O'Connor PBF, Loughran G, Weissman JS, Baranov PV, Rodnina MV, Puglisi JD, Atkins JF. PMID: 32454154.
      View in: PubMed   Mentions:    Fields:    
    7. Inference of single-cell phylogenies from lineage tracing data using Cassiopeia. Genome Biol. 2020 04 14; 21(1):92. Jones MG, Khodaverdian A, Quinn JJ, Chan MM, Hussmann JA, Wang R, Xu C, Weissman JS, Yosef N. PMID: 32290857.
      View in: PubMed   Mentions:    Fields:    
    8. CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma. Genome Biol. 2020 03 31; 21(1):83. Liu SJ, Malatesta M, Lien BV, Saha P, Thombare SS, Hong SJ, Pedraza L, Koontz M, Seo K, Horlbeck MA, He D, Birk HS, Jain M, Olsen HE, Akeson M, Weissman JS, Monje M, Gupta N, Raleigh DR, Ullian EM, Lim DA. PMID: 32234056.
      View in: PubMed   Mentions: 2     Fields:    
    9. Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing. Nat Biotechnol. 2020 08; 38(8):954-961. Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, Weissman JS, Adamson B. PMID: 32231336.
      View in: PubMed   Mentions: 3     Fields:    
    10. Pervasive functional translation of noncanonical human open reading frames. Science. 2020 03 06; 367(6482):1140-1146. Chen J, Brunner AD, Cogan JZ, Nuñez JK, Fields AP, Adamson B, Itzhak DN, Li JY, Mann M, Leonetti MD, Weissman JS. PMID: 32139545.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    11. Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes. Nat Biotechnol. 2020 05; 38(5):573-576. Horlbeck MA, Liu SJ, Chang HY, Lim DA, Weissman JS. PMID: 32094656.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    12. Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs. Nat Biotechnol. 2020 03; 38(3):355-364. Jost M, Santos DA, Saunders RA, Horlbeck MA, Hawkins JS, Scaria SM, Norman TM, Hussmann JA, Liem CR, Gross CA, Weissman JS. PMID: 31932729.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    13. The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration. Genes Dev. 2020 02 01; 34(3-4):194-208. Vargas EJM, Matamoros AJ, Qiu J, Jan CH, Wang Q, Gorczyca D, Han TW, Weissman JS, Jan YN, Banerjee S, Song Y. PMID: 31919191.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    14. The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins. Elife. 2019 09 13; 8. Ngo AM, Shurtleff MJ, Popova KD, Kulsuptrakul J, Weissman JS, Puschnik AS. PMID: 31516121.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    15. New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells. J Cell Biol. 2019 11 04; 218(11):3861-3879. Bassaganyas L, Popa SJ, Horlbeck M, Puri C, Stewart SE, Campelo F, Ashok A, Butnaru CM, Brouwers N, Heydari K, Ripoche J, Weissman J, Rubinsztein DC, Schekman R, Malhotra V, Moreau K, Villeneuve J. PMID: 31488582.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    16. Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science. 2019 08 23; 365(6455):786-793. Norman TM, Horlbeck MA, Replogle JM, Ge AY, Xu A, Jost M, Gilbert LA, Weissman JS. PMID: 31395745.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    17. MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices. Nat Methods. 2019 07; 16(7):619-626. McGinnis CS, Patterson DM, Winkler J, Conrad DN, Hein MY, Srivastava V, Hu JL, Murrow LM, Weissman JS, Werb Z, Chow ED, Gartner ZJ. PMID: 31209384.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    18. Cycloheximide can distort measurements of mRNA levels and translation efficiency. Nucleic Acids Res. 2019 06 04; 47(10):4974-4985. Santos DA, Shi L, Tu BP, Weissman JS. PMID: 30916348.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    19. Ceapins block the unfolded protein response sensor ATF6a by inducing a neomorphic inter-organelle tether. Elife. 2019 05 31; 8. Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. PMID: 31149896.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    20. Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11291-11298. Igbaria A, Merksamer PI, Trusina A, Tilahun F, Johnson JR, Brandman O, Krogan NJ, Weissman JS, Papa FR. PMID: 31101715.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    21. Molecular recording of mammalian embryogenesis. Nature. 2019 06; 570(7759):77-82. Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. PMID: 31086336.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    22. Ribosome Profiling: Global Views of Translation. Cold Spring Harb Perspect Biol. 2019 05 01; 11(5). Ingolia NT, Hussmann JA, Weissman JS. PMID: 30037969.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    23. Cellular response to small molecules that selectively stall protein synthesis by the ribosome. PLoS Genet. 2019 03; 15(3):e1008057. Liaud N, Horlbeck MA, Gilbert LA, Gjoni K, Weissman JS, Cate JHD. PMID: 30875366.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    24. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Mol Cell. 2019 04 04; 74(1):32-44.e8. Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, Farese RV. PMID: 30846318.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    25. Mapping the Genetic Landscape of Human Cells. Cell. 2018 08 09; 174(4):953-967.e22. Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. PMID: 30033366.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    26. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). J Med Chem. 2018 Jul 26; 61(14):6163-6177. Shao H, Li X, Moses MA, Gilbert LA, Kalyanaraman C, Young ZT, Chernova M, Journey SN, Weissman JS, Hann B, Jacobson MP, Neckers L, Gestwicki JE. PMID: 29953808.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    27. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. 2018 07; 559(7714):405-409. Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, Chen JW, Schickel JN, Pellerin L, Carmody D, Alkorta-Aranburu G, Del Gaudio D, Matsumoto H, Morell M, Mao Y, Cho M, Quadros RM, Gurumurthy CB, Smith B, Haugwitz M, Hughes SH, Weissman JS, Schumann K, Esensten JH, May AP, Ashworth A, Kupfer GM, Greeley SAW, Bacchetta R, Meffre E, Roncarolo MG, Romberg N, Herold KC, Ribas A, Leonetti MD, Marson A. PMID: 29995861.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    28. Engineering ER-stress dependent non-conventional mRNA splicing. Elife. 2018 07 09; 7. Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P. PMID: 29985129.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    29. The helicase Ded1p controls use of near-cognate translation initiation codons in 5' UTRs. Nature. 2018 07; 559(7712):130-134. Guenther UP, Weinberg DE, Zubradt MM, Tedeschi FA, Stawicki BN, Zagore LL, Brar GA, Licatalosi DD, Bartel DP, Weissman JS, Jankowsky E. PMID: 29950728.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    30. The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. Elife. 2018 05 29; 7. Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH, Weissman JS. PMID: 29809151.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    31. Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform. Hepatology. 2018 08; 68(2):663-676. Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. PMID: 29091290.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    32. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates. Elife. 2018 05 10; 7. Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. PMID: 29745899.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    33. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. 2018 05 31; 173(6):1398-1412.e22. Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, Weissman JS, Curtis C, Chang HY. PMID: 29731168.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    34. A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation. Mol Cell. 2018 04 19; 70(2):274-286.e7. Zhang Y, Burkhardt DH, Rouskin S, Li GW, Weissman JS, Gross CA. PMID: 29628307.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    35. CRISPR Approaches to Small Molecule Target Identification. ACS Chem Biol. 2018 02 16; 13(2):366-375. Jost M, Weissman JS. PMID: 29261286.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    36. Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins. Elife. 2018 01 23; 7. Martinko AJ, Truillet C, Julien O, Diaz JE, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans MJ, Wells JA. PMID: 29359686.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    37. Defining the physiological role of SRP in protein-targeting efficiency and specificity. Science. 2018 02 09; 359(6376):689-692. Costa EA, Subramanian K, Nunnari J, Weissman JS. PMID: 29348368.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    38. Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER. Dev Cell. 2018 01 22; 44(2):261-270.e6. Friedman JR, Kannan M, Toulmay A, Jan CH, Weissman JS, Prinz WA, Nunnari J. PMID: 29290583.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    39. The Human Cell Atlas. Elife. 2017 12 05; 6. Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N. PMID: 29206104.
      View in: PubMed   Mentions: 157     Fields:    Translation:HumansCells
    40. Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors. Nat Methods. 2017 Dec; 14(12):1163-1166. Tak YE, Kleinstiver BP, Nuñez JK, Hsu JY, Horng JE, Gong J, Weissman JS, Joung JK. PMID: 29083402.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    41. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Mol Cell. 2017 Oct 05; 68(1):210-223.e6. Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. PMID: 28985505.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    42. CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Science. 2017 07 28; 357(6349):414-417. Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, Weinberg DE, Weissman JS. PMID: 28751611.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    43. Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia. Blood. 2017 06 01; 129(22):3000-3008. Kruth KA, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA. PMID: 28424165.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    44. Operon mRNAs are organized into ORF-centric structures that predict translation efficiency. Elife. 2017 01 31; 6. Burkhardt DH, Rouskin S, Zhang Y, Li GW, Weissman JS, Gross CA. PMID: 28139975.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    45. Translation from unconventional 5' start sites drives tumour initiation. Nature. 2017 01 26; 541(7638):494-499. Sendoel A, Dunn JG, Rodriguez EH, Naik S, Gomez NC, Hurwitz B, Levorse J, Dill BD, Schramek D, Molina H, Weissman JS, Fuchs E. PMID: 28077873.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    46. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 01 06; 355(6320). Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, Weissman JS, Lim DA. PMID: 27980086.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansCells
    47. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016 Dec 15; 167(7):1853-1866.e17. Dixit A, Parnas O, Li B, Chen J, Fulco CP, Jerby-Arnon L, Marjanovic ND, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman TM, Lander ES, Weissman JS, Friedman N, Regev A. PMID: 27984732.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    48. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15; 167(7):1867-1882.e21. Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS. PMID: 27984733.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    49. The mTOR Complex Controls HIV Latency. . 2016 Dec 14; 20(6):785-797. Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E. PMID: 27978436.
      View in: PubMed   Mentions:
    50. The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. Nature. 2016 11 30; 540(7631):134-138. Aviram N, Ast T, Costa EA, Arakel EC, Chuartzman SG, Jan CH, Haßdenteufel S, Dudek J, Jung M, Schorr S, Zimmermann R, Schwappach B, Weissman JS, Schuldiner M. PMID: 27905431.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    51. Plastid: nucleotide-resolution analysis of next-generation sequencing and genomics data. BMC Genomics. 2016 11 22; 17(1):958. Dunn JG, Weissman JS. PMID: 27875984.
      View in: PubMed   Mentions: 27     Fields:    
    52. Model-guided optogenetic study of PKA signaling in budding yeast. Mol Biol Cell. 2017 01 01; 28(1):221-227. Stewart-Ornstein J, Chen S, Bhatnagar R, Weissman JS, El-Samad H. PMID: 28035051.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    53. DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo. Nat Methods. 2017 01; 14(1):75-82. Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. PMID: 27819661.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    54. Dynamic translation regulation in Caulobacter cell cycle control. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):E6859-E6867. Schrader JM, Li GW, Childers WS, Perez AM, Weissman JS, Shapiro L, McAdams HH. PMID: 27791168.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    55. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 09 23; 5. Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. PMID: 27661255.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    56. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 08 09; 113(32):9015-20. Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. PMID: 27450084.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    57. Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity. Nat Commun. 2016 07 01; 7:12009. Nguyen DP, Miyaoka Y, Gilbert LA, Mayerl SJ, Lee BH, Weissman JS, Conklin BR, Wells JA. PMID: 27363581.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    58. Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation. Proc Natl Acad Sci U S A. 2016 07 12; 113(28):E4015-24. Liu YC, Fujimori DG, Weissman JS. PMID: 27357682.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    59. Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):E3892-900. Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT. PMID: 27325776.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    60. A scalable strategy for high-throughput GFP tagging of endogenous human proteins. Proc Natl Acad Sci U S A. 2016 06 21; 113(25):E3501-8. Leonetti MD, Sekine S, Kamiyama D, Weissman JS, Huang B. PMID: 27274053.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    61. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. Cell. 2016 Jun 02; 165(6):1493-1506. Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CHS, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA. PMID: 27238023.
      View in: PubMed   Mentions: 101     Fields:    Translation:Cells
    62. Single-cell analysis of long non-coding RNAs in the developing human neocortex. Genome Biol. 2016 Apr 14; 17:67. Liu SJ, Nowakowski TJ, Pollen AA, Lui JH, Horlbeck MA, Attenello FJ, He D, Weissman JS, Kriegstein AR, Diaz AA, Lim DA. PMID: 27081004.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    63. Versatile protein tagging in cells with split fluorescent protein. Nat Commun. 2016 Mar 18; 7:11046. Kamiyama D, Sekine S, Barsi-Rhyne B, Hu J, Chen B, Gilbert LA, Ishikawa H, Leonetti MD, Marshall WF, Weissman JS, Huang B. PMID: 26988139.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    64. Nucleosomes impede Cas9 access to DNA in vivo and in vitro. Elife. 2016 03 17; 5. Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tjian R, Weissman JS. PMID: 26987018.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    65. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. 2016 Apr 07; 18(4):541-53. Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. PMID: 26971820.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    66. A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. Mol Cell. 2015 Dec 03; 60(5):816-827. Fields AP, Rodriguez EH, Jovanovic M, Stern-Ginossar N, Haas BJ, Mertins P, Raychowdhury R, Hacohen N, Carr SA, Ingolia NT, Regev A, Weissman JS. PMID: 26638175.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    67. [KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis. Mol Cell. 2015 Nov 19; 60(4):651-60. Suzuki G, Weissman JS, Tanaka M. PMID: 26590718.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    68. Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis. Cancer Cell. 2015 Nov 09; 28(5):653-665. Anderson DJ, Le Moigne R, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Kiss von Soly S, Madriaga A, Soriano F, Menon MK, Wu ZY, Kampmann M, Chen Y, Weissman JS, Aftab BT, Yakes FM, Shawver L, Zhou HJ, Wustrow D, Rolfe M. PMID: 26555175.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    69. Ribosome profiling reveals the what, when, where and how of protein synthesis. Nat Rev Mol Cell Biol. 2015 Nov; 16(11):651-64. Brar GA, Weissman JS. PMID: 26465719.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    70. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 2015 Sep 01; 4:e08153. Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. PMID: 26327694.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    71. Regulation of mRNA translation during mitosis. Elife. 2015 Aug 25; 4. Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD. PMID: 26305499.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    72. Next-generation libraries for robust RNA interference-based genome-wide screens. Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26):E3384-91. Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. PMID: 26080438.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    73. LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". Science. 2015 Jun 12; 348(6240):1217. Jan CH, Williams CC, Weissman JS. PMID: 26068842.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    74. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 2015 Apr 15; 4:e07314. Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. PMID: 25875391.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    75. Corrigendum: functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nat Protoc. 2015 Apr; 10(4):643. Kampmann M, Bassik MC, Weissman JS. PMID: 25811902.
      View in: PubMed   Mentions:    Fields:    
    76. Biotechnology. A prudent path forward for genomic engineering and germline gene modification. Science. 2015 Apr 03; 348(6230):36-8. Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, Sternberg SH, Weissman JS, Yamamoto KR. PMID: 25791083.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansCells
    77. Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens. Science. 2015 Mar 06; 347(6226):1259038. Jovanovic M, Rooney MS, Mertins P, Przybylski D, Chevrier N, Satija R, Rodriguez EH, Fields AP, Schwartz S, Raychowdhury R, Mumbach MR, Eisenhaure T, Rabani M, Gennert D, Lu D, Delorey T, Weissman JS, Carr SA, Hacohen N, Regev A. PMID: 25745177.
      View in: PubMed   Mentions: 126     Fields:    Translation:AnimalsCells
    78. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer. . 2015 Mar; 14(3):642-8. Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. PMID: 25564440.
      View in: PubMed   Mentions:
    79. Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Science. 2015 Jan 02; 347(6217):75-8. Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. PMID: 25554787.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    80. Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation. Mol Syst Biol. 2014 Dec 23; 10:770. Pop C, Rouskin S, Ingolia NT, Han L, Phizicky EM, Weissman JS, Koller D. PMID: 25538139.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    81. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell. 2015 Jan 15; 160(1-2):339-50. Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA. PMID: 25533786.
      View in: PubMed   Mentions: 204     Fields:    Translation:HumansAnimalsCells
    82. Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 07; 346(6210):748-51. Williams CC, Jan CH, Weissman JS. PMID: 25378625.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    83. Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 07; 346(6210):1257521. Jan CH, Williams CC, Weissman JS. PMID: 25378630.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    84. The general mode of translation inhibition by macrolide antibiotics. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):15958-63. Kannan K, Kanabar P, Schryer D, Florin T, Oh E, Bahroos N, Tenson T, Weissman JS, Mankin AS. PMID: 25349425.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    85. Genetic influences on translation in yeast. PLoS Genet. 2014 Oct; 10(10):e1004692. Albert FW, Muzzey D, Weissman JS, Kruglyak L. PMID: 25340754.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    86. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 2014 Oct 23; 159(3):647-61. Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. PMID: 25307932.
      View in: PubMed   Mentions: 516     Fields:    Translation:HumansCells
    87. A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell. 2014 Oct 23; 159(3):635-46. Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. PMID: 25307933.
      View in: PubMed   Mentions: 232     Fields:    Translation:HumansAnimalsCells
    88. Unraveling the mechanism of cell death induced by chemical fibrils. Nat Chem Biol. 2014 Nov; 10(11):969-76. Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. PMID: 25262416.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    89. Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. Cell Rep. 2014 Sep 11; 8(5):1365-79. Ingolia NT, Brar GA, Stern-Ginossar N, Harris MS, Talhouarne GJ, Jackson SE, Wills MR, Weissman JS. PMID: 25159147.
      View in: PubMed   Mentions: 174     Fields:    Translation:HumansAnimalsCells
    90. Misfolded proteins induce aggregation of the lectin Yos9. J Biol Chem. 2014 Sep 12; 289(37):25670-7. Smith MH, Rodriguez EH, Weissman JS. PMID: 25086047.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    91. The coding and noncoding architecture of the Caulobacter crescentus genome. PLoS Genet. 2014 Jul; 10(7):e1004463. Schrader JM, Zhou B, Li GW, Lasker K, Childers WS, Williams B, Long T, Crosson S, McAdams HH, Weissman JS, Shapiro L. PMID: 25078267.
      View in: PubMed   Mentions: 53     Fields:    Translation:Cells
    92. Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nat Protoc. 2014 Aug; 9(8):1825-47. Kampmann M, Bassik MC, Weissman JS. PMID: 24992097.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    93. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nat Commun. 2014 May 08; 5:3832. van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, Lebbink RJ. PMID: 24807418.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    94. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science. 2014 May 30; 344(6187):1042-7. Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. PMID: 24789973.
      View in: PubMed   Mentions: 96     Fields:    Translation:Cells
    95. Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell. 2014 Apr 24; 157(3):624-35. Li GW, Burkhardt D, Gross C, Weissman JS. PMID: 24766808.
      View in: PubMed   Mentions: 320     Fields:    Translation:AnimalsCells
    96. Extensive and coordinated control of allele-specific expression by both transcription and translation in Candida albicans. Genome Res. 2014 Jun; 24(6):963-73. Muzzey D, Sherlock G, Weissman JS. PMID: 24732588.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    97. Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol. 2014 Mar 31; 204(7):1083-6. Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J. PMID: 24687277.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    98. Differential scales of protein quality control. Cell. 2014 Mar 27; 157(1):52-64. Wolff S, Weissman JS, Dillin A. PMID: 24679526.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    99. KSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and functional features. PLoS Pathog. 2014 Jan; 10(1):e1003847. Arias C, Weisburd B, Stern-Ginossar N, Mercier A, Madrid AS, Bellare P, Holdorf M, Weissman JS, Ganem D. PMID: 24453964.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    100. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell. 2013 Dec 19; 155(7):1479-91. Chen B, Gilbert LA, Cimini BA, Schnitzbauer J, Zhang W, Li GW, Park J, Blackburn EH, Weissman JS, Qi LS, Huang B. PMID: 24360272.
      View in: PubMed   Mentions: 443     Fields:    Translation:HumansCells
    101. Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature. 2014 Jan 30; 505(7485):701-5. Rouskin S, Zubradt M, Washietl S, Kellis M, Weissman JS. PMID: 24336214.
      View in: PubMed   Mentions: 252     Fields:    Translation:HumansAnimalsCells
    102. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Elife. 2013 Dec 03; 2:e01179. Dunn JG, Foo CK, Belletier NG, Gavis ER, Weissman JS. PMID: 24302569.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    103. Msn2 coordinates a stoichiometric gene expression program. Curr Biol. 2013 Dec 02; 23(23):2336-45. Stewart-Ornstein J, Nelson C, DeRisi J, Weissman JS, El-Samad H. PMID: 24210615.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    104. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chem Biol. 2013 Nov 21; 20(11):1352-63. Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. PMID: 24183972.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    105. Global cellular response to chemotherapy-induced apoptosis. Elife. 2013 Oct 29; 2:e01236. Wiita AP, Ziv E, Wiita PJ, Urisman A, Julien O, Burlingame AL, Weissman JS, Wells JA. PMID: 24171104.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    106. CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nat Protoc. 2013 Nov; 8(11):2180-96. Larson MH, Gilbert LA, Wang X, Lim WA, Weissman JS, Qi LS. PMID: 24136345.
      View in: PubMed   Mentions: 193     Fields:    Translation:Cells
    107. Selective ribosome profiling as a tool for studying the interaction of chaperones and targeting factors with nascent polypeptide chains and ribosomes. Nat Protoc. 2013 Nov; 8(11):2212-39. Becker AH, Oh E, Weissman JS, Kramer G, Bukau B. PMID: 24136347.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    108. A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern. Genes Dev. 2013 Oct 01; 27(19):2147-63. Berchowitz LE, Gajadhar AS, van Werven FJ, De Rosa AA, Samoylova ML, Brar GA, Xu Y, Xiao C, Futcher B, Weissman JS, White FM, Amon A. PMID: 24115771.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    109. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell. 2013 Jul 18; 154(2):442-51. Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS. PMID: 23849981.
      View in: PubMed   Mentions: 793     Fields:    Translation:HumansAnimalsCells
    110. Genome-wide annotation and quantitation of translation by ribosome profiling. Curr Protoc Mol Biol. 2013 Jul; Chapter 4:Unit 4.18. Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. PMID: 23821443.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    111. Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. Cell. 2013 Jul 03; 154(1):240-51. Guttman M, Russell P, Ingolia NT, Weissman JS, Lander ES. PMID: 23810193.
      View in: PubMed   Mentions: 240     Fields:    Translation:AnimalsCells
    112. Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):E2317-26. Kampmann M, Bassik MC, Weissman JS. PMID: 23739767.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    113. rRNA:mRNA pairing alters the length and the symmetry of mRNA-protected fragments in ribosome profiling experiments. Bioinformatics. 2013 Jun 15; 29(12):1488-91. O'Connor PB, Li GW, Weissman JS, Atkins JF, Baranov PV. PMID: 23603333.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    114. Aneuploid yeast strains exhibit defects in cell growth and passage through START. Mol Biol Cell. 2013 May; 24(9):1274-89. Thorburn RR, Gonzalez C, Brar GA, Christen S, Carlile TM, Ingolia NT, Sauer U, Weissman JS, Amon A. PMID: 23468524.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    115. The contribution of systematic approaches to characterizing the proteins and functions of the endoplasmic reticulum. Cold Spring Harb Perspect Biol. 2013 Mar 01; 5(3):a013284. Schuldiner M, Weissman JS. PMID: 23359093.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    116. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell. 2013 Feb 28; 152(5):1173-83. Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. PMID: 23452860.
      View in: PubMed   Mentions: 956     Fields:    Translation:Cells
    117. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 2013 Feb 14; 152(4):909-22. Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. PMID: 23394947.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansCells
    118. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biol. 2013; 14(9):R97. Muzzey D, Schwartz K, Weissman JS, Sherlock G. PMID: 24025428.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    119. Decoding human cytomegalovirus. Science. 2012 Nov 23; 338(6110):1088-93. Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein MY, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman JS. PMID: 23180859.
      View in: PubMed   Mentions: 233     Fields:    Translation:HumansCells
    120. A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress. Cell. 2012 Nov 21; 151(5):1042-54. Brandman O, Stewart-Ornstein J, Wong D, Larson A, Williams CC, Li GW, Zhou S, King D, Shen PS, Weibezahn J, Dunn JG, Rouskin S, Inada T, Frost A, Weissman JS. PMID: 23178123.
      View in: PubMed   Mentions: 180     Fields:    Translation:AnimalsCells
    121. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nat Protoc. 2012 Jul 26; 7(8):1534-50. Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. PMID: 22836135.
      View in: PubMed   Mentions: 332     Fields:    Translation:HumansAnimalsCells
    122. Proto-genes and de novo gene birth. Nature. 2012 Jul 19; 487(7407):370-4. Carvunis AR, Rolland T, Wapinski I, Calderwood MA, Yildirim MA, Simonis N, Charloteaux B, Hidalgo CA, Barbette J, Santhanam B, Brar GA, Weissman JS, Regev A, Thierry-Mieg N, Cusick ME, Vidal M. PMID: 22722833.
      View in: PubMed   Mentions: 177     Fields:    Translation:AnimalsCells
    123. Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell. 2012 Jun 08; 149(6):1339-52. Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein MY, Poser I, Mann M, Hyman AA, Weissman JS. PMID: 22682253.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    124. Special issue: the molecular and cellular mechanisms of amyloidosis. J Mol Biol. 2012 Aug 10; 421(2-3):139-41. Radford SE, Weissman JS. PMID: 22664198.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    125. Native elongating transcript sequencing (NET-seq). Curr Protoc Mol Biol. 2012 Apr; Chapter 4:Unit 4.14.1-17. Churchman LS, Weissman JS. PMID: 22470065.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    126. The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria. Nature. 2012 Mar 28; 484(7395):538-41. Li GW, Oh E, Weissman JS. PMID: 22456704.
      View in: PubMed   Mentions: 255     Fields:    Translation:Cells
    127. Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae. Mol Cell. 2012 Feb 24; 45(4):483-93. Stewart-Ornstein J, Weissman JS, El-Samad H. PMID: 22365828.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    128. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 2012 Feb 22; 485(7396):55-61. Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, Weissman JS, Shokat KM, Rommel C, Ruggero D. PMID: 22367541.
      View in: PubMed   Mentions: 455     Fields:    Translation:HumansAnimalsCells
    129. High-resolution view of the yeast meiotic program revealed by ribosome profiling. Science. 2012 Feb 03; 335(6068):552-7. Brar GA, Yassour M, Friedman N, Regev A, Ingolia NT, Weissman JS. PMID: 22194413.
      View in: PubMed   Mentions: 235     Fields:    Translation:AnimalsCells
    130. Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo. Cell. 2011 Dec 09; 147(6):1295-308. Oh E, Becker AH, Sandikci A, Huber D, Chaba R, Gloge F, Nichols RJ, Typas A, Gross CA, Kramer G, Weissman JS, Bukau B. PMID: 22153074.
      View in: PubMed   Mentions: 153     Fields:    Translation:Cells
    131. Genetics: Noise rules. Nature. 2011 Dec 07; 480(7376):188-9. El-Samad H, Weissman JS. PMID: 22158239.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    132. Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science. 2011 Nov 25; 334(6059):1086-90. Smith MH, Ploegh HL, Weissman JS. PMID: 22116878.
      View in: PubMed   Mentions: 252     Fields:    Translation:HumansAnimalsCells
    133. Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19222-7. Roelants FM, Breslow DK, Muir A, Weissman JS, Thorner J. PMID: 22080611.
      View in: PubMed   Mentions: 113     Fields:    Translation:AnimalsCells
    134. Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell. 2011 Nov 11; 147(4):789-802. Ingolia NT, Lareau LF, Weissman JS. PMID: 22056041.
      View in: PubMed   Mentions: 743     Fields:    Translation:AnimalsCells
    135. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol. 2011 Oct 17; 195(2):323-40. Hoppins S, Collins SR, Cassidy-Stone A, Hummel E, Devay RM, Lackner LL, Westermann B, Schuldiner M, Weissman JS, Nunnari J. PMID: 21987634.
      View in: PubMed   Mentions: 135     Fields:    Translation:AnimalsCells
    136. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature. 2011 Aug 03; 476(7358):88-91. Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D. PMID: 21814281.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    137. H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway. Mol Cell Biol. 2011 Sep; 31(17):3569-83. Terzi N, Churchman LS, Vasiljeva L, Weissman J, Buratowski S. PMID: 21709022.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    138. Strain conformation, primary structure and the propagation of the yeast prion [PSI+]. Nat Struct Mol Biol. 2011 Apr; 18(4):493-9. Verges KJ, Smith MH, Toyama BH, Weissman JS. PMID: 21423194.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    139. Radically different amyloid conformations dictate the seeding specificity of a chimeric Sup35 prion. J Mol Biol. 2011 Apr 22; 408(1):1-8. Foo CK, Ohhashi Y, Kelly MJ, Tanaka M, Weissman JS. PMID: 21333653.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    140. Nascent transcript sequencing visualizes transcription at nucleotide resolution. Nature. 2011 Jan 20; 469(7330):368-73. Churchman LS, Weissman JS. PMID: 21248844.
      View in: PubMed   Mentions: 312     Fields:    Translation:AnimalsCells
    141. Amyloid structure: conformational diversity and consequences. Annu Rev Biochem. 2011; 80:557-85. Toyama BH, Weissman JS. PMID: 21456964.
      View in: PubMed   Mentions: 65     Fields:    Translation:Cells
    142. Systematic screen of Schizosaccharomyces pombe deletion collection uncovers parallel evolution of the phosphate signal transduction pathway in yeasts. Eukaryot Cell. 2011 Feb; 10(2):198-206. Henry TC, Power JE, Kerwin CL, Mohammed A, Weissman JS, Cameron DM, Wykoff DD. PMID: 21169418.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    143. The epistemology of cell biology. Mol Biol Cell. 2010 Nov 15; 21(22):3825. Weissman JS. PMID: 21079033.
      View in: PubMed   Mentions: 1     Fields:    
    144. Membranes in balance: mechanisms of sphingolipid homeostasis. Mol Cell. 2010 Oct 22; 40(2):267-79. Breslow DK, Weissman JS. PMID: 20965421.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    145. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 2010 Aug 12; 466(7308):835-40. Guo H, Ingolia NT, Weissman JS, Bartel DP. PMID: 20703300.
      View in: PubMed   Mentions: 1598     Fields:    Translation:HumansAnimalsCells
    146. Automated identification of pathways from quantitative genetic interaction data. Mol Syst Biol. 2010 Jun 08; 6:379. Battle A, Jonikas MC, Walter P, Weissman JS, Koller D. PMID: 20531408.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    147. A general lack of compensation for gene dosage in yeast. Mol Syst Biol. 2010 May 11; 6:368. Springer M, Weissman JS, Kirschner MW. PMID: 20461075.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    148. J domain co-chaperone specificity defines the role of BiP during protein translocation. J Biol Chem. 2010 Jul 16; 285(29):22484-94. Vembar SS, Jonikas MC, Hendershot LM, Weissman JS, Brodsky JL. PMID: 20430885.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    149. Molecular basis of infrared detection by snakes. Nature. 2010 Apr 15; 464(7291):1006-11. Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D. PMID: 20228791.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    150. Orm family proteins mediate sphingolipid homeostasis. Nature. 2010 Feb 25; 463(7284):1048-53. Breslow DK, Collins SR, Bodenmiller B, Aebersold R, Simons K, Shevchenko A, Ejsing CS, Weissman JS. PMID: 20182505.
      View in: PubMed   Mentions: 214     Fields:    Translation:HumansAnimalsCells
    151. Differences in prion strain conformations result from non-native interactions in a nucleus. Nat Chem Biol. 2010 Mar; 6(3):225-230. Ohhashi Y, Ito K, Toyama BH, Weissman JS, Tanaka M. PMID: 20081853.
      View in: PubMed   Mentions: 34     Fields:    
    152. Journal club. A biochemist looks at how DNA sequencing can reveal more than just sequences. Nature. 2009 Oct 29; 461(7268):1177. Weissman J. PMID: 19865125.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    153. From information to knowledge: new technologies for defining gene function. Nat Methods. 2009 Oct; 6(10):721-23. Collins SR, Weissman JS, Krogan NJ. PMID: 19953683.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    154. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol. 2009 Aug 10; 186(3):323-31. Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. PMID: 19651891.
      View in: PubMed   Mentions: 337     Fields:    Translation:AnimalsCells
    155. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science. 2009 Jul 24; 325(5939):477-81. Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P. PMID: 19556461.
      View in: PubMed   Mentions: 393     Fields:    Translation:AnimalsCells
    156. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat Methods. 2009 Jun; 6(6):443-5. Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. PMID: 19448642.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    157. Analysis of Dom34 and its function in no-go decay. Mol Biol Cell. 2009 Jul; 20(13):3025-32. Passos DO, Doma MK, Shoemaker CJ, Muhlrad D, Green R, Weissman J, Hollien J, Parker R. PMID: 19420139.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    158. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009 Mar 27; 323(5922):1693-7. Jonikas MC, Collins SR, Denic V, Oh E, Quan EM, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman JS, Schuldiner M. PMID: 19325107.
      View in: PubMed   Mentions: 243     Fields:    Translation:AnimalsCells
    159. Functional organization of the S. cerevisiae phosphorylation network. Cell. 2009 Mar 06; 136(5):952-63. Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, Shokat KM, Krogan NJ. PMID: 19269370.
      View in: PubMed   Mentions: 141     Fields:    Translation:AnimalsCells
    160. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science. 2009 Apr 10; 324(5924):218-23. Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. PMID: 19213877.
      View in: PubMed   Mentions: 1220     Fields:    Translation:AnimalsCells
    161. Defining the glycan destruction signal for endoplasmic reticulum-associated degradation. Mol Cell. 2008 Dec 26; 32(6):870-7. Quan EM, Kamiya Y, Kamiya D, Denic V, Weibezahn J, Kato K, Weissman JS. PMID: 19111666.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    162. A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell. 2008 Dec 05; 32(5):735-46. Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ. PMID: 19061648.
      View in: PubMed   Mentions: 138     Fields:    Translation:AnimalsCells
    163. In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104. Mol Cell. 2008 Nov 21; 32(4):584-91. Tipton KA, Verges KJ, Weissman JS. PMID: 19026788.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    164. Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network. Nat Biotechnol. 2008 Nov; 26(11):1251-9. Chechik G, Oh E, Rando O, Weissman J, Regev A, Koller D. PMID: 18953355.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    165. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Science. 2008 Oct 17; 322(5900):405-10. Roguev A, Bandyopadhyay S, Zofall M, Zhang K, Fischer T, Collins SR, Qu H, Shales M, Park HO, Hayles J, Hoe KL, Kim DU, Ideker T, Grewal SI, Weissman JS, Krogan NJ. PMID: 18818364.
      View in: PubMed   Mentions: 182     Fields:    Translation:AnimalsCells
    166. High-throughput, quantitative analyses of genetic interactions in E. coli. Nat Methods. 2008 Sep; 5(9):781-7. Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. PMID: 19160513.
      View in: PubMed   Mentions: 101     Fields:    Translation:Cells
    167. Systems biology: Reverse engineering the cell. Nature. 2008 Aug 28; 454(7208):1059-62. Ingolia NT, Weissman JS. PMID: 18756243.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    168. The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell. 2008 Aug 22; 134(4):634-45. Schuldiner M, Metz J, Schmid V, Denic V, Rakwalska M, Schmitt HD, Schwappach B, Weissman JS. PMID: 18724936.
      View in: PubMed   Mentions: 175     Fields:    Translation:AnimalsCells
    169. A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods. 2008 Aug; 5(8):711-8. Breslow DK, Cameron DM, Collins SR, Schuldiner M, Stewart-Ornstein J, Newman HW, Braun S, Madhani HD, Krogan NJ, Weissman JS. PMID: 18622397.
      View in: PubMed   Mentions: 215     Fields:    Translation:Animals
    170. Small-molecule aggregates inhibit amyloid polymerization. Nat Chem Biol. 2008 Mar; 4(3):197-9. Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. PMID: 18223646.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    171. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18079-84. Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. PMID: 17989219.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    172. High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe. Nat Methods. 2007 Oct; 4(10):861-6. Roguev A, Wiren M, Weissman JS, Krogan NJ. PMID: 17893680.
      View in: PubMed   Mentions: 76     Fields:    Translation:Animals
    173. The structural basis of yeast prion strain variants. Nature. 2007 Sep 13; 449(7159):233-7. Toyama BH, Kelly MJ, Gross JD, Weissman JS. PMID: 17767153.
      View in: PubMed   Mentions: 162     Fields:    Translation:AnimalsCells
    174. A molecular caliper mechanism for determining very long-chain fatty acid length. Cell. 2007 Aug 24; 130(4):663-77. Denic V, Weissman JS. PMID: 17719544.
      View in: PubMed   Mentions: 77     Fields:    Translation:Cells
    175. Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell. 2007 Aug 10; 130(3):499-511. Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X. PMID: 17693258.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    176. Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss. Mol Syst Biol. 2007; 3:86. Ihmels J, Collins SR, Schuldiner M, Krogan NJ, Weissman JS. PMID: 17389874.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    177. CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):5836-41. Laribee RN, Shibata Y, Mersman DP, Collins SR, Kemmeren P, Roguev A, Weissman JS, Briggs SD, Krogan NJ, Strahl BD. PMID: 17389396.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    178. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature. 2007 Apr 12; 446(7137):806-10. Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, Andrews B, Boone C, Berger SL, Hieter P, Zhang Z, Brown GW, Ingles CJ, Emili A, Allis CD, Toczyski DP, Weissman JS, Greenblatt JF, Krogan NJ. PMID: 17314980.
      View in: PubMed   Mentions: 474     Fields:    Translation:AnimalsCells
    179. Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Mol Cell Proteomics. 2007 Mar; 6(3):439-50. Collins SR, Kemmeren P, Zhao XC, Greenblatt JF, Spencer F, Holstege FC, Weissman JS, Krogan NJ. PMID: 17200106.
      View in: PubMed   Mentions: 308     Fields:    Translation:Animals
    180. Systems biology: many things from one. Nature. 2006 Nov 30; 444(7119):561-2. Newman JR, Weissman JS. PMID: 17122769.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    181. A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation. Cell. 2006 Jul 28; 126(2):349-59. Denic V, Quan EM, Weissman JS. PMID: 16873065.
      View in: PubMed   Mentions: 182     Fields:    Translation:AnimalsCells
    182. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science. 2006 Jul 07; 313(5783):104-7. Hollien J, Weissman JS. PMID: 16825573.
      View in: PubMed   Mentions: 411     Fields:    Translation:AnimalsCells
    183. The physical basis of how prion conformations determine strain phenotypes. Nature. 2006 Aug 03; 442(7102):585-9. Tanaka M, Collins SR, Toyama BH, Weissman JS. PMID: 16810177.
      View in: PubMed   Mentions: 262     Fields:    Translation:AnimalsCells
    184. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature. 2006 Jun 15; 441(7095):840-6. Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. PMID: 16699522.
      View in: PubMed   Mentions: 589     Fields:    Translation:Animals
    185. Molecular chaperones and protein quality control. Cell. 2006 May 05; 125(3):443-51. Bukau B, Weissman J, Horwich A. PMID: 16678092.
      View in: PubMed   Mentions: 513     Fields:    Translation:HumansAnimalsCells
    186. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30; 440(7084):637-43. Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O'Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF. PMID: 16554755.
      View in: PubMed   Mentions: 1085     Fields:    Translation:AnimalsCells
    187. A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biol. 2006; 7(7):R63. Collins SR, Schuldiner M, Krogan NJ, Weissman JS. PMID: 16859555.
      View in: PubMed   Mentions: 160     Fields:    
    188. An efficient protein transformation protocol for introducing prions into yeast. Methods Enzymol. 2006; 412:185-200. Tanaka M, Weissman JS. PMID: 17046659.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    189. Domain architecture of protein-disulfide isomerase facilitates its dual role as an oxidase and an isomerase in Ero1p-mediated disulfide formation. J Biol Chem. 2006 Jan 13; 281(2):876-84. Kulp MS, Frickel EM, Ellgaard L, Weissman JS. PMID: 16368681.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    190. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell. 2005 Nov 18; 123(4):593-605. Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, Grunstein M, Greenblatt JF, Buratowski S, Krogan NJ. PMID: 16286008.
      View in: PubMed   Mentions: 391     Fields:    Translation:AnimalsCells
    191. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell. 2005 Nov 04; 123(3):507-19. Schuldiner M, Collins SR, Thompson NJ, Denic V, Bhamidipati A, Punna T, Ihmels J, Andrews B, Boone C, Greenblatt JF, Weissman JS, Krogan NJ. PMID: 16269340.
      View in: PubMed   Mentions: 407     Fields:    Translation:AnimalsCells
    192. Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen. Mol Cell. 2005 Sep 16; 19(6):741-51. Bhamidipati A, Denic V, Quan EM, Weissman JS. PMID: 16168370.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    193. Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins. Cell. 2005 Apr 08; 121(1):49-62. Tanaka M, Chien P, Yonekura K, Weissman JS. PMID: 15820678.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    194. Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. Comp Funct Genomics. 2005; 6(1-2):2-16. Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK. PMID: 18629296.
      View in: PubMed   Mentions:
    195. 2004 Irving Sigal Young Investigator Award. Protein Sci. 2004 Dec; 13(12):3333-5. Weissman JS, O'Shea EK. PMID: 15557272.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    196. Mechanism of prion propagation: amyloid growth occurs by monomer addition. PLoS Biol. 2004 Oct; 2(10):e321. Collins SR, Douglass A, Vale RD, Weissman JS. PMID: 15383837.
      View in: PubMed   Mentions: 169     Fields:    
    197. Dissection and design of yeast prions. PLoS Biol. 2004 Apr; 2(4):E86. Osherovich LZ, Cox BS, Tuite MF, Weissman JS. PMID: 15045026.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    198. Conformational variations in an infectious protein determine prion strain differences. Nature. 2004 Mar 18; 428(6980):323-8. Tanaka M, Chien P, Naber N, Cooke R, Weissman JS. PMID: 15029196.
      View in: PubMed   Mentions: 320     Fields:    Translation:AnimalsCells
    199. Oxidative protein folding in eukaryotes: mechanisms and consequences. J Cell Biol. 2004 Feb 02; 164(3):341-6. Tu BP, Weissman JS. PMID: 14757749.
      View in: PubMed   Mentions: 280     Fields:    Translation:HumansAnimalsCells
    200. Emerging principles of conformation-based prion inheritance. Annu Rev Biochem. 2004; 73:617-56. Chien P, Weissman JS, DePace AH. PMID: 15189155.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    201. Global analysis of protein localization in budding yeast. Nature. 2003 Oct 16; 425(6959):686-91. Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. PMID: 14562095.
      View in: PubMed   Mentions: 1658     Fields:    Translation:AnimalsCells
    202. Global analysis of protein expression in yeast. Nature. 2003 Oct 16; 425(6959):737-41. Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. PMID: 14562106.
      View in: PubMed   Mentions: 1599     Fields:    Translation:Animals
    203. Generation of prion transmission barriers by mutational control of amyloid conformations. Nature. 2003 Aug 21; 424(6951):948-51. Chien P, DePace AH, Collins SR, Weissman JS. PMID: 12931190.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    204. Directed evolution of substrate-optimized GroEL/S chaperonins. Cell. 2002 Dec 27; 111(7):1027-39. Wang JD, Herman C, Tipton KA, Gross CA, Weissman JS. PMID: 12507429.
      View in: PubMed   Mentions: 48     Fields:    Translation:Cells
    205. The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum. Mol Cell. 2002 Nov; 10(5):983-94. Tu BP, Weissman JS. PMID: 12453408.
      View in: PubMed   Mentions: 122     Fields:    Translation:AnimalsCells
    206. Origins and kinetic consequences of diversity in Sup35 yeast prion fibers. Nat Struct Biol. 2002 May; 9(5):389-96. DePace AH, Weissman JS. PMID: 11938354.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    207. The utility of prions. Dev Cell. 2002 Feb; 2(2):143-51. Osherovich LZ, Weissman JS. PMID: 11832240.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
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