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Jonathan Weissman, PhD

Title(s)Professor, Cellular Molecular Pharmacology
SchoolSchool of Medicine
Phone415-502-7642
EmailJonathan.Weissman@ucsf.edu
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    Other Positions
    Title(s)Professor, School of Medicine


    Collapse Research 
    Collapse Research Activities and Funding
    The Cancer Target Discovery and Development Network at UCSF
    NIH/NCI U01CA217882Aug 10, 2017 - Jul 31, 2022
    Role: Co-Principal Investigator
    Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming
    NIH/NIDA R01DA036858Sep 30, 2013 - May 31, 2018
    Role: Principal Investigator
    Structural Basis of Protein Homeostasis
    NIH/NIGMS U01GM098254Sep 30, 2012 - Jul 31, 2015
    Role: Co-Principal Investigator
    Human Gene Knockdowns that May Extend Lifespan
    NIH/NIA R01AG041826May 1, 2012 - Apr 30, 2017
    Role: Principal Investigator
    Bay Area Cancer Target Discovery and Development Network
    NIH/NCI U01CA168370May 1, 2012 - Apr 30, 2017
    Role: Co-Principal Investigator
    MECHANISM OF CHAPERONE MEDIATED PROTEIN FOLDING
    NIH/NIGMS R01GM055595May 1, 1997 - Apr 30, 2002
    Role: Principal Investigator
    Molecular Pathogenesis of Age-Dependent CNS Regeneration
    NIH/NIA P01AG010770Apr 1, 1993 - Mar 31, 2016
    Role: Co-Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wynn-Jones W, Koehlmoos TP, Tompkins C, Navathe A, Lipsitz S, Kwon NK, Learn PA, Madsen C, Schoenfeld A, Weissman JS. Variation in expenditure for common, high cost surgical procedures in a working age population: implications for reimbursement reform. BMC Health Serv Res. 2019 Nov 21; 19(1):877. PMID: 31752866.
      View in: PubMed
    2. Ngo AM, Shurtleff MJ, Popova KD, Kulsuptrakul J, Weissman JS, Puschnik AS. The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins. Elife. 2019 09 13; 8. PMID: 31516121.
      View in: PubMed
    3. Bassaganyas L, Popa SJ, Horlbeck M, Puri C, Stewart SE, Campelo F, Ashok A, Butnaru CM, Brouwers N, Heydari K, Ripoche J, Weissman J, Rubinsztein DC, Schekman R, Malhotra V, Moreau K, Villeneuve J. New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells. J Cell Biol. 2019 Nov 04; 218(11):3861-3879. PMID: 31488582.
      View in: PubMed
    4. Norman TM, Horlbeck MA, Replogle JM, Ge AY, Xu A, Jost M, Gilbert LA, Weissman JS. Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science. 2019 08 23; 365(6455):786-793. PMID: 31395745.
      View in: PubMed
    5. McGinnis CS, Patterson DM, Winkler J, Conrad DN, Hein MY, Srivastava V, Hu JL, Murrow LM, Weissman JS, Werb Z, Chow ED, Gartner ZJ. MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices. Nat Methods. 2019 07; 16(7):619-626. PMID: 31209384.
      View in: PubMed
    6. Santos DA, Shi L, Tu BP, Weissman JS. Cycloheximide can distort measurements of mRNA levels and translation efficiency. Nucleic Acids Res. 2019 Jun 04; 47(10):4974-4985. PMID: 30916348.
      View in: PubMed
    7. Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Ceapins block the unfolded protein response sensor ATF6a by inducing a neomorphic inter-organelle tether. Elife. 2019 05 31; 8. PMID: 31149896.
      View in: PubMed
    8. Igbaria A, Merksamer PI, Trusina A, Tilahun F, Johnson JR, Brandman O, Krogan NJ, Weissman JS, Papa FR. Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress. Proc Natl Acad Sci U S A. 2019 Jun 04; 116(23):11291-11298. PMID: 31101715.
      View in: PubMed
    9. Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. Molecular recording of mammalian embryogenesis. Nature. 2019 06; 570(7759):77-82. PMID: 31086336.
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    10. Ingolia NT, Hussmann JA, Weissman JS. Ribosome Profiling: Global Views of Translation. Cold Spring Harb Perspect Biol. 2019 May 01; 11(5). PMID: 30037969.
      View in: PubMed
    11. Liaud N, Horlbeck MA, Gilbert LA, Gjoni K, Weissman JS, Cate JHD. Cellular response to small molecules that selectively stall protein synthesis by the ribosome. PLoS Genet. 2019 03; 15(3):e1008057. PMID: 30875366.
      View in: PubMed
    12. Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, Farese RV. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Mol Cell. 2019 04 04; 74(1):32-44.e8. PMID: 30846318.
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    13. Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. Mapping the Genetic Landscape of Human Cells. Cell. 2018 08 09; 174(4):953-967.e22. PMID: 30033366.
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    14. Shao H, Li X, Moses MA, Gilbert LA, Kalyanaraman C, Young ZT, Chernova M, Journey SN, Weissman JS, Hann B, Jacobson MP, Neckers L, Gestwicki JE. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). J Med Chem. 2018 Jul 26; 61(14):6163-6177. PMID: 29953808.
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    15. Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, Chen JW, Schickel JN, Pellerin L, Carmody D, Alkorta-Aranburu G, Del Gaudio D, Matsumoto H, Morell M, Mao Y, Cho M, Quadros RM, Gurumurthy CB, Smith B, Haugwitz M, Hughes SH, Weissman JS, Schumann K, Esensten JH, May AP, Ashworth A, Kupfer GM, Greeley SAW, Bacchetta R, Meffre E, Roncarolo MG, Romberg N, Herold KC, Ribas A, Leonetti MD, Marson A. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. 2018 07; 559(7714):405-409. PMID: 29995861.
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    16. Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P. Engineering ER-stress dependent non-conventional mRNA splicing. Elife. 2018 07 09; 7. PMID: 29985129.
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    17. Guenther UP, Weinberg DE, Zubradt MM, Tedeschi FA, Stawicki BN, Zagore LL, Brar GA, Licatalosi DD, Bartel DP, Weissman JS, Jankowsky E. The helicase Ded1p controls use of near-cognate translation initiation codons in 5' UTRs. Nature. 2018 07; 559(7712):130-134. PMID: 29950728.
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    18. Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH, Weissman JS. The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. Elife. 2018 05 29; 7. PMID: 29809151.
      View in: PubMed
    19. Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform. Hepatology. 2018 08; 68(2):663-676. PMID: 29091290.
      View in: PubMed
    20. Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates. Elife. 2018 05 10; 7. PMID: 29745899.
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    21. Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, Weissman JS, Curtis C, Chang HY. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. 2018 05 31; 173(6):1398-1412.e22. PMID: 29731168.
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    22. Zhang Y, Burkhardt DH, Rouskin S, Li GW, Weissman JS, Gross CA. A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation. Mol Cell. 2018 04 19; 70(2):274-286.e7. PMID: 29628307.
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    23. Jost M, Weissman JS. CRISPR Approaches to Small Molecule Target Identification. ACS Chem Biol. 2018 02 16; 13(2):366-375. PMID: 29261286.
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    24. Martinko AJ, Truillet C, Julien O, Diaz JE, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans MJ, Wells JA. Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins. Elife. 2018 01 23; 7. PMID: 29359686.
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    25. Costa EA, Subramanian K, Nunnari J, Weissman JS. Defining the physiological role of SRP in protein-targeting efficiency and specificity. Science. 2018 02 09; 359(6376):689-692. PMID: 29348368.
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    26. Friedman JR, Kannan M, Toulmay A, Jan CH, Weissman JS, Prinz WA, Nunnari J. Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER. Dev Cell. 2018 01 22; 44(2):261-270.e6. PMID: 29290583.
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    27. Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N. The Human Cell Atlas. Elife. 2017 12 05; 6. PMID: 29206104.
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    28. Tak YE, Kleinstiver BP, Nuñez JK, Hsu JY, Horng JE, Gong J, Weissman JS, Joung JK. Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors. Nat Methods. 2017 Dec; 14(12):1163-1166. PMID: 29083402.
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    29. Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Mol Cell. 2017 Oct 05; 68(1):210-223.e6. PMID: 28985505.
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    30. Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, Weinberg DE, Weissman JS. CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Science. 2017 07 28; 357(6349):414-417. PMID: 28751611.
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    31. Sood A, Meyer CP, Abdollah F, Sammon JD, Sun M, Lipsitz SR, Hollis M, Weissman JS, Menon M, Trinh QD. Minimally invasive surgery and its impact on 30-day postoperative complications, unplanned readmissions and mortality. Br J Surg. 2017 Sep; 104(10):1372-1381. PMID: 28632890.
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    32. Kruth KA, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA. Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia. Blood. 2017 06 01; 129(22):3000-3008. PMID: 28424165.
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    33. Burkhardt DH, Rouskin S, Zhang Y, Li GW, Weissman JS, Gross CA. Operon mRNAs are organized into ORF-centric structures that predict translation efficiency. Elife. 2017 01 31; 6. PMID: 28139975.
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    34. Sendoel A, Dunn JG, Rodriguez EH, Naik S, Gomez NC, Hurwitz B, Levorse J, Dill BD, Schramek D, Molina H, Weissman JS, Fuchs E. Translation from unconventional 5' start sites drives tumour initiation. Nature. 2017 01 26; 541(7638):494-499. PMID: 28077873.
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    35. Dixit A, Parnas O, Li B, Chen J, Fulco CP, Jerby-Arnon L, Marjanovic ND, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman TM, Lander ES, Weissman JS, Friedman N, Regev A. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016 Dec 15; 167(7):1853-1866.e17. PMID: 27984732.
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    36. Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15; 167(7):1867-1882.e21. PMID: 27984733.
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    37. Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, Weissman JS, Lim DA. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 01 06; 355(6320). PMID: 27980086.
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    38. Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E. The mTOR Complex Controls HIV Latency. Cell Host Microbe. 2016 Dec 14; 20(6):785-797. PMID: 27978436.
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    39. Aviram N, Ast T, Costa EA, Arakel EC, Chuartzman SG, Jan CH, Haßdenteufel S, Dudek J, Jung M, Schorr S, Zimmermann R, Schwappach B, Weissman JS, Schuldiner M. The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. Nature. 2016 11 30; 540(7631):134-138. PMID: 27905431.
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    40. Dunn JG, Weissman JS. Plastid: nucleotide-resolution analysis of next-generation sequencing and genomics data. BMC Genomics. 2016 11 22; 17(1):958. PMID: 27875984.
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    41. Stewart-Ornstein J, Chen S, Bhatnagar R, Weissman JS, El-Samad H. Model-guided optogenetic study of PKA signaling in budding yeast. Mol Biol Cell. 2017 01 01; 28(1):221-227. PMID: 28035051.
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    42. Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo. Nat Methods. 2017 01; 14(1):75-82. PMID: 27819661.
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    43. Schrader JM, Li GW, Childers WS, Perez AM, Weissman JS, Shapiro L, McAdams HH. Dynamic translation regulation in Caulobacter cell cycle control. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):E6859-E6867. PMID: 27791168.
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    44. Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 09 23; 5. PMID: 27661255.
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    45. Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 08 09; 113(32):9015-20. PMID: 27450084.
      View in: PubMed
    46. Nguyen DP, Miyaoka Y, Gilbert LA, Mayerl SJ, Lee BH, Weissman JS, Conklin BR, Wells JA. Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity. Nat Commun. 2016 07 01; 7:12009. PMID: 27363581.
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    47. Liu YC, Fujimori DG, Weissman JS. Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation. Proc Natl Acad Sci U S A. 2016 07 12; 113(28):E4015-24. PMID: 27357682.
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    48. Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT. Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):E3892-900. PMID: 27325776.
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    49. Leonetti MD, Sekine S, Kamiyama D, Weissman JS, Huang B. A scalable strategy for high-throughput GFP tagging of endogenous human proteins. Proc Natl Acad Sci U S A. 2016 06 21; 113(25):E3501-8. PMID: 27274053.
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    50. Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CHS, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. Cell. 2016 Jun 02; 165(6):1493-1506. PMID: 27238023.
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    51. Liu SJ, Nowakowski TJ, Pollen AA, Lui JH, Horlbeck MA, Attenello FJ, He D, Weissman JS, Kriegstein AR, Diaz AA, Lim DA. Single-cell analysis of long non-coding RNAs in the developing human neocortex. Genome Biol. 2016 Apr 14; 17:67. PMID: 27081004.
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    52. Kamiyama D, Sekine S, Barsi-Rhyne B, Hu J, Chen B, Gilbert LA, Ishikawa H, Leonetti MD, Marshall WF, Weissman JS, Huang B. Versatile protein tagging in cells with split fluorescent protein. Nat Commun. 2016 Mar 18; 7:11046. PMID: 26988139.
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    53. Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tjian R, Weissman JS. Nucleosomes impede Cas9 access to DNA in vivo and in vitro. Elife. 2016 03 17; 5. PMID: 26987018.
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    54. Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. 2016 Apr 07; 18(4):541-53. PMID: 26971820.
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    55. Fields AP, Rodriguez EH, Jovanovic M, Stern-Ginossar N, Haas BJ, Mertins P, Raychowdhury R, Hacohen N, Carr SA, Ingolia NT, Regev A, Weissman JS. A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. Mol Cell. 2015 Dec 03; 60(5):816-827. PMID: 26638175.
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    56. Suzuki G, Weissman JS, Tanaka M. [KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis. Mol Cell. 2015 Nov 19; 60(4):651-60. PMID: 26590718.
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    57. Anderson DJ, Le Moigne R, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Kiss von Soly S, Madriaga A, Soriano F, Menon MK, Wu ZY, Kampmann M, Chen Y, Weissman JS, Aftab BT, Yakes FM, Shawver L, Zhou HJ, Wustrow D, Rolfe M. Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis. Cancer Cell. 2015 Nov 09; 28(5):653-665. PMID: 26555175.
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    58. Brar GA, Weissman JS. Ribosome profiling reveals the what, when, where and how of protein synthesis. Nat Rev Mol Cell Biol. 2015 Nov; 16(11):651-64. PMID: 26465719.
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    59. Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 2015 Sep 01; 4:e08153. PMID: 26327694.
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    60. Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD. Regulation of mRNA translation during mitosis. Elife. 2015 Aug 25; 4. PMID: 26305499.
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    61. Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. Next-generation libraries for robust RNA interference-based genome-wide screens. Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26):E3384-91. PMID: 26080438.
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    62. Jan CH, Williams CC, Weissman JS. LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". Science. 2015 Jun 12; 348(6240):1217. PMID: 26068842.
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    63. Pazarentzos E, Giannikopoulos P, Hrustanovic G, St John J, Olivas VR, Gubens MA, Balassanian R, Weissman J, Polkinghorn W, Bivona TG. Oncogenic activation of the PI3-kinase p110ß isoform via the tumor-derived PIK3Cß(D1067V) kinase domain mutation. Oncogene. 2016 Mar 03; 35(9):1198-205. PMID: 25982275.
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    64. Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 2015 Apr 15; 4:e07314. PMID: 25875391.
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    65. Kampmann M, Bassik MC, Weissman JS. Corrigendum: functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nat Protoc. 2015 Apr; 10(4):643. PMID: 25811902.
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    66. Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, Sternberg SH, Weissman JS, Yamamoto KR. Biotechnology. A prudent path forward for genomic engineering and germline gene modification. Science. 2015 Apr 03; 348(6230):36-8. PMID: 25791083.
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    67. Jovanovic M, Rooney MS, Mertins P, Przybylski D, Chevrier N, Satija R, Rodriguez EH, Fields AP, Schwartz S, Raychowdhury R, Mumbach MR, Eisenhaure T, Rabani M, Gennert D, Lu D, Delorey T, Weissman JS, Carr SA, Hacohen N, Regev A. Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens. Science. 2015 Mar 06; 347(6226):1259038. PMID: 25745177.
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    68. Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer. Mol Cancer Ther. 2015 Mar; 14(3):642-8. PMID: 25564440.
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    69. Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Science. 2015 Jan 02; 347(6217):75-8. PMID: 25554787.
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    70. Pop C, Rouskin S, Ingolia NT, Han L, Phizicky EM, Weissman JS, Koller D. Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation. Mol Syst Biol. 2014 Dec 23; 10:770. PMID: 25538139.
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    71. Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell. 2015 Jan 15; 160(1-2):339-50. PMID: 25533786.
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    72. Williams CC, Jan CH, Weissman JS. Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 07; 346(6210):748-51. PMID: 25378625.
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    73. Jan CH, Williams CC, Weissman JS. Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 07; 346(6210):1257521. PMID: 25378630.
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    74. Kannan K, Kanabar P, Schryer D, Florin T, Oh E, Bahroos N, Tenson T, Weissman JS, Mankin AS. The general mode of translation inhibition by macrolide antibiotics. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):15958-63. PMID: 25349425.
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    75. Albert FW, Muzzey D, Weissman JS, Kruglyak L. Genetic influences on translation in yeast. PLoS Genet. 2014 Oct; 10(10):e1004692. PMID: 25340754.
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    126. Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature. 2011 Aug 03; 476(7358):88-91. PMID: 21814281.
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    127. Terzi N, Churchman LS, Vasiljeva L, Weissman J, Buratowski S. H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway. Mol Cell Biol. 2011 Sep; 31(17):3569-83. PMID: 21709022.
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    146. Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat Methods. 2009 Jun; 6(6):443-5. PMID: 19448642.
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    147. Passos DO, Doma MK, Shoemaker CJ, Muhlrad D, Green R, Weissman J, Hollien J, Parker R. Analysis of Dom34 and its function in no-go decay. Mol Biol Cell. 2009 Jul; 20(13):3025-32. PMID: 19420139.
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    148. Jonikas MC, Collins SR, Denic V, Oh E, Quan EM, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman JS, Schuldiner M. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009 Mar 27; 323(5922):1693-7. PMID: 19325107.
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    149. Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, Shokat KM, Krogan NJ. Functional organization of the S. cerevisiae phosphorylation network. Cell. 2009 Mar 06; 136(5):952-63. PMID: 19269370.
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    151. Quan EM, Kamiya Y, Kamiya D, Denic V, Weibezahn J, Kato K, Weissman JS. Defining the glycan destruction signal for endoplasmic reticulum-associated degradation. Mol Cell. 2008 Dec 26; 32(6):870-7. PMID: 19111666.
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    152. Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ. A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell. 2008 Dec 05; 32(5):735-46. PMID: 19061648.
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    153. Tipton KA, Verges KJ, Weissman JS. In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104. Mol Cell. 2008 Nov 21; 32(4):584-91. PMID: 19026788.
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    154. Chechik G, Oh E, Rando O, Weissman J, Regev A, Koller D. Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network. Nat Biotechnol. 2008 Nov; 26(11):1251-9. PMID: 18953355.
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    156. Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. High-throughput, quantitative analyses of genetic interactions in E. coli. Nat Methods. 2008 Sep; 5(9):781-7. PMID: 19160513.
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    157. Ingolia NT, Weissman JS. Systems biology: Reverse engineering the cell. Nature. 2008 Aug 28; 454(7208):1059-62. PMID: 18756243.
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    175. Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature. 2006 Jun 15; 441(7095):840-6. PMID: 16699522.
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    176. Bukau B, Weissman J, Horwich A. Molecular chaperones and protein quality control. Cell. 2006 May 05; 125(3):443-51. PMID: 16678092.
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    177. Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O'Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30; 440(7084):637-43. PMID: 16554755.
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    178. Collins SR, Schuldiner M, Krogan NJ, Weissman JS. A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biol. 2006; 7(7):R63. PMID: 16859555.
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    179. Tanaka M, Weissman JS. An efficient protein transformation protocol for introducing prions into yeast. Methods Enzymol. 2006; 412:185-200. PMID: 17046659.
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    180. Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, Grunstein M, Greenblatt JF, Buratowski S, Krogan NJ. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell. 2005 Nov 18; 123(4):593-605. PMID: 16286008.
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    181. Kulp MS, Frickel EM, Ellgaard L, Weissman JS. Domain architecture of protein-disulfide isomerase facilitates its dual role as an oxidase and an isomerase in Ero1p-mediated disulfide formation. J Biol Chem. 2006 Jan 13; 281(2):876-84. PMID: 16368681.
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    182. Schuldiner M, Collins SR, Thompson NJ, Denic V, Bhamidipati A, Punna T, Ihmels J, Andrews B, Boone C, Greenblatt JF, Weissman JS, Krogan NJ. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell. 2005 Nov 04; 123(3):507-19. PMID: 16269340.
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    183. Bhamidipati A, Denic V, Quan EM, Weissman JS. Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen. Mol Cell. 2005 Sep 16; 19(6):741-51. PMID: 16168370.
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    184. Tanaka M, Chien P, Yonekura K, Weissman JS. Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins. Cell. 2005 Apr 08; 121(1):49-62. PMID: 15820678.
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    185. Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK. Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. Comp Funct Genomics. 2005; 6(1-2):2-16. PMID: 18629296.
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    186. Weissman JS, O'Shea EK. 2004 Irving Sigal Young Investigator Award. Protein Sci. 2004 Dec; 13(12):3333-5. PMID: 15557272.
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    187. Collins SR, Douglass A, Vale RD, Weissman JS. Mechanism of prion propagation: amyloid growth occurs by monomer addition. PLoS Biol. 2004 Oct; 2(10):e321. PMID: 15383837.
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    188. Osherovich LZ, Cox BS, Tuite MF, Weissman JS. Dissection and design of yeast prions. PLoS Biol. 2004 Apr; 2(4):E86. PMID: 15045026.
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    189. Tanaka M, Chien P, Naber N, Cooke R, Weissman JS. Conformational variations in an infectious protein determine prion strain differences. Nature. 2004 Mar 18; 428(6980):323-8. PMID: 15029196.
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    190. Tu BP, Weissman JS. Oxidative protein folding in eukaryotes: mechanisms and consequences. J Cell Biol. 2004 Feb 02; 164(3):341-6. PMID: 14757749.
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    191. Chien P, Weissman JS, DePace AH. Emerging principles of conformation-based prion inheritance. Annu Rev Biochem. 2004; 73:617-56. PMID: 15189155.
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    192. Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. Global analysis of protein expression in yeast. Nature. 2003 Oct 16; 425(6959):737-41. PMID: 14562106.
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    193. Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. Global analysis of protein localization in budding yeast. Nature. 2003 Oct 16; 425(6959):686-91. PMID: 14562095.
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    194. Chien P, DePace AH, Collins SR, Weissman JS. Generation of prion transmission barriers by mutational control of amyloid conformations. Nature. 2003 Aug 21; 424(6951):948-51. PMID: 12931190.
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    195. Wang JD, Herman C, Tipton KA, Gross CA, Weissman JS. Directed evolution of substrate-optimized GroEL/S chaperonins. Cell. 2002 Dec 27; 111(7):1027-39. PMID: 12507429.
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    196. Tu BP, Weissman JS. The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum. Mol Cell. 2002 Nov; 10(5):983-94. PMID: 12453408.
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    197. DePace AH, Weissman JS. Origins and kinetic consequences of diversity in Sup35 yeast prion fibers. Nat Struct Biol. 2002 May; 9(5):389-96. PMID: 11938354.
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    198. Osherovich LZ, Weissman JS. The utility of prions. Dev Cell. 2002 Feb; 2(2):143-51. PMID: 11832240.
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    199. Weissman JS, Hood JK. Prion diseases. A rogue protein. Lancet. 2001 Dec; 358 Suppl:S53. PMID: 11784602.
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    200. Weissman JS. The ins and outs of GroEL-mediated protein folding. Mol Cell. 2001 Oct; 8(4):730-2. PMID: 11684006.
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    201. Schneider EC, Leape LL, Weissman JS, Piana RN, Gatsonis C, Epstein AM. Racial differences in cardiac revascularization rates: does "overuse" explain higher rates among white patients? Ann Intern Med. 2001 Sep 04; 135(5):328-37. PMID: 11529696.
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    202. Blumenthal D, Causino N, Campbell EG, Weissman JS. The relationship of market forces to the satisfaction of faculty at academic health centers. Am J Med. 2001 Sep; 111(4):333-40. PMID: 11566469.
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    203. Weissman JS, Campbell EG, Gokhale M, Blumenthal D. Residents' preferences and preparation for caring for underserved populations. J Urban Health. 2001 Sep; 78(3):535-49. PMID: 11564855.
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    204. Osherovich LZ, Weissman JS. Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion. Cell. 2001 Jul 27; 106(2):183-94. PMID: 11511346.
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    205. Chien P, Weissman JS. Conformational diversity in a yeast prion dictates its seeding specificity. Nature. 2001 Mar 08; 410(6825):223-7. PMID: 11242084.
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    206. Aridor M, Fish KN, Bannykh S, Weissman J, Roberts TH, Lippincott-Schwartz J, Balch WE. The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. J Cell Biol. 2001 Jan 08; 152(1):213-29. PMID: 11149932.
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    207. Fewell SW, Travers KJ, Weissman JS, Brodsky JL. The action of molecular chaperones in the early secretory pathway. Annu Rev Genet. 2001; 35:149-91. PMID: 11700281.
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    208. Travers KJ, Patil CK, Weissman JS. Functional genomic approaches to understanding molecular chaperones and stress responses. Adv Protein Chem. 2001; 59:345-90. PMID: 11868277.
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    209. Tu BP, Ho-Schleyer SC, Travers KJ, Weissman JS. Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science. 2000 Nov 24; 290(5496):1571-4. PMID: 11090354.
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    210. Epstein AM, Ayanian JZ, Keogh JH, Noonan SJ, Armistead N, Cleary PD, Weissman JS, David-Kasdan JA, Carlson D, Fuller J, Marsh D, Conti RM. Racial disparities in access to renal transplantation--clinically appropriate or due to underuse or overuse? N Engl J Med. 2000 Nov 23; 343(21):1537-44, 2 p preceding 1537. PMID: 11087884.
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    211. Ayanian JZ, Weissman JS, Schneider EC, Ginsburg JA, Zaslavsky AM. Unmet health needs of uninsured adults in the United States. JAMA. 2000 Oct 25; 284(16):2061-9. PMID: 11042754.
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    212. Michelitsch MD, Weissman JS. A census of glutamine/asparagine-rich regions: implications for their conserved function and the prediction of novel prions. Proc Natl Acad Sci U S A. 2000 Oct 24; 97(22):11910-5. PMID: 11050225.
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    213. Sparrer HE, Santoso A, Szoka FC, Weissman JS. Evidence for the prion hypothesis: induction of the yeast [PSI+] factor by in vitro- converted Sup35 protein. Science. 2000 Jul 28; 289(5479):595-9. PMID: 10915616.
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    214. Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, Walter P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell. 2000 Apr 28; 101(3):249-58. PMID: 10847680.
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    215. Allan BB, Weissman J, Aridor M, Moyer B, Chen CD, Yoo JS, Balch WE. Stage-specific assays to study biosynthetic cargo selection and role of SNAREs in export from the endoplasmic reticulum and delivery to the Golgi. Methods. 2000 Apr; 20(4):411-6. PMID: 10720462.
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    216. Santoso A, Chien P, Osherovich LZ, Weissman JS. Molecular basis of a yeast prion species barrier. Cell. 2000 Jan 21; 100(2):277-88. PMID: 10660050.
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    217. Ayanian JZ, Weissman JS, Chasan-Taber S, Epstein AM. Quality of care by race and gender for congestive heart failure and pneumonia. Med Care. 1999 Dec; 37(12):1260-9. PMID: 10599607.
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    218. Ayanian JZ, Cleary PD, Weissman JS, Epstein AM. The effect of patients' preferences on racial differences in access to renal transplantation. N Engl J Med. 1999 Nov 25; 341(22):1661-9. PMID: 10572155.
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    219. Blumenthal D, Weissman JS, Griner PF. Academic health centers on the front lines: survival strategies in highly competitive markets. Acad Med. 1999 Sep; 74(9):1038-49. PMID: 10498101.
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    220. Wang JD, Weissman JS. Thinking outside the box: new insights into the mechanism of GroEL-mediated protein folding. Nat Struct Biol. 1999 Jul; 6(7):597-600. PMID: 10404205.
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    221. Weissman JS, Ayanian JZ, Chasan-Taber S, Sherwood MJ, Roth C, Epstein AM. Hospital readmissions and quality of care. Med Care. 1999 May; 37(5):490-501. PMID: 10335751.
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    222. Weissman JS, Saglam D, Campbell EG, Causino N, Blumenthal D. Market forces and unsponsored research in academic health centers. JAMA. 1999 Mar 24-31; 281(12):1093-8. PMID: 10188659.
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    223. Weissman JS, Witzburg R, Linov P, Campbell EG. Termination from Medicaid: how does it affect access, continuity of care, and willingness to purchase insurance? J Health Care Poor Underserved. 1999 Feb; 10(1):122-37. PMID: 9989010.
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    224. Weissman JS, Haas JS, Fowler FJ, Gatsonis C, Massagli MP, Seage GR, Cleary P. The stability of preferences for life-sustaining care among persons with AIDS in the Boston Health Study. Med Decis Making. 1999 Jan-Mar; 19(1):16-26. PMID: 9917016.
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    225. Wang JD, Michelitsch MD, Weissman JS. GroEL-GroES-mediated protein folding requires an intact central cavity. Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21):12163-8. PMID: 9770457.
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    226. DePace AH, Santoso A, Hillner P, Weissman JS. A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion. Cell. 1998 Jun 26; 93(7):1241-52. PMID: 9657156.
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    227. Wilson IB, Sullivan LM, Weissman JS. Costs and outcomes of AIDS care: comparing a health maintenance organization with fee-for-service systems in the Boston Health Study. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Apr 15; 17(5):424-32. PMID: 9562045.
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    228. Aridor M, Weissman J, Bannykh S, Nuoffer C, Balch WE. Cargo selection by the COPII budding machinery during export from the ER. J Cell Biol. 1998 Apr 06; 141(1):61-70. PMID: 9531548.
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    229. Pollard MG, Travers KJ, Weissman JS. Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum. Mol Cell. 1998 Jan; 1(2):171-82. PMID: 9659914.
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    230. Horwich AL, Burston SG, Rye HS, Weissman JS, Fenton WA. Construction of single-ring and two-ring hybrid versions of bacterial chaperonin GroEL. Methods Enzymol. 1998; 290:141-6. PMID: 9534157.
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    231. Weissman JS. Commentary: economic transfers, the changing face of a familiar problem. Health Serv Res. 1997 Dec; 32(5):591-8. PMID: 9402902.
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    232. Horwich AL, Weissman JS. Deadly conformations--protein misfolding in prion disease. Cell. 1997 May 16; 89(4):499-510. PMID: 9160742.
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    233. Weissman JS, Cleary PD, Seage GR, Gatsonis C, Haas JS, Chasan-Taber S, Epstein AM. The influence of health-related quality of life and social characteristics on hospital use by patients with AIDS in the Boston Health Study. Med Care. 1996 Oct; 34(10):1037-56. PMID: 8843929.
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    234. Weissman J. Uncompensated hospital care. Will it be there if we need it? JAMA. 1996 Sep 11; 276(10):823-8. PMID: 8769594.
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    235. Burston SG, Weissman JS, Farr GW, Fenton WA, Horwich AL. Release of both native and non-native proteins from a cis-only GroEL ternary complex. Nature. 1996 Sep 05; 383(6595):96-9. PMID: 8779722.
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    236. Weissman JS, Levin K, Chasan-Taber S, Massagli MP, Seage GR, Scampini L. The validity of self-reported health-care utilization by AIDS patients. AIDS. 1996 Jun; 10(7):775-83. PMID: 8805870.
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    237. Fenton WA, Weissman JS, Horwich AL. Putting a lid on protein folding: structure and function of the co-chaperonin, GroES. Chem Biol. 1996 Mar; 3(3):157-61. PMID: 8807841.
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    238. Weissman JS, Rye HS, Fenton WA, Beechem JM, Horwich AL. Characterization of the active intermediate of a GroEL-GroES-mediated protein folding reaction. Cell. 1996 Feb 09; 84(3):481-90. PMID: 8608602.
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    239. Weissman JS, Kim PS. A kinetic explanation for the rearrangement pathway of BPTI folding. Nat Struct Biol. 1995 Dec; 2(12):1123-30. PMID: 8846225.
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    240. Weissman JS, Hohl CM, Kovalenko O, Kashi Y, Chen S, Braig K, Saibil HR, Fenton WA, Horwich AL. Mechanism of GroEL action: productive release of polypeptide from a sequestered position under GroES. Cell. 1995 Nov 17; 83(4):577-87. PMID: 7585961.
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    241. Yu MH, Weissman JS, Kim PS. Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. J Mol Biol. 1995 Jun 02; 249(2):388-97. PMID: 7540212.
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    242. Weissman JS. All roads lead to Rome? The multiple pathways of protein folding. Chem Biol. 1995 May; 2(5):255-60. PMID: 9383427.
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    243. Weissman JS, Sigler PB, Horwich AL. From the cradle to the grave: ring complexes in the life of a protein. Science. 1995 Apr 28; 268(5210):523-4. PMID: 7725096.
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    244. Horwich AL, Weissman JS, Fenton WA. Kinesis of polypeptide during GroEL-mediated folding. Cold Spring Harb Symp Quant Biol. 1995; 60:435-40. PMID: 8824417.
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    245. Epstein AM, Seage G, Weissman JS, Cleary PD, Fowler FJ, Gatsonis C, Massagli MP, Stone VE, Coltin K, Craven DE. Costs of medical care and out-of-pocket expenditures for persons with AIDS in the Boston Health Study. Inquiry. 1995; 32(2):211-21. PMID: 7601519.
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    246. Weissman JS, Kashi Y, Fenton WA, Horwich AL. GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms. Cell. 1994 Aug 26; 78(4):693-702. PMID: 7915201.
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    247. Craig EA, Weissman JS, Horwich AL. Heat shock proteins and molecular chaperones: mediators of protein conformation and turnover in the cell. Cell. 1994 Aug 12; 78(3):365-72. PMID: 7914834.
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    248. Ettner SL, Weissman J. Utilization of formal and informal home care by AIDS patients in Boston: a comparison of intravenous drug users and homosexual males. Med Care. 1994 May; 32(5):459-70. PMID: 8182974.
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    249. Mort EA, Weissman JS, Epstein AM. Physician discretion and racial variation in the use of surgical procedures. Arch Intern Med. 1994 Apr 11; 154(7):761-7. PMID: 8147680.
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    250. Weissman JS, Stern RS, Epstein AM. The impact of patient socioeconomic status and other social factors on readmission: a prospective study in four Massachusetts hospitals. Inquiry. 1994; 31(2):163-72. PMID: 8021022.
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    251. Weissman JS, Kim PS. Efficient catalysis of disulphide bond rearrangements by protein disulphide isomerase. Nature. 1993 Sep 09; 365(6442):185-8. PMID: 7690463.
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    252. Cleary PD, Fowler FJ, Weissman J, Massagli MP, Wilson I, Seage GR, Gatsonis C, Epstein A. Health-related quality of life in persons with acquired immune deficiency syndrome. Med Care. 1993 Jul; 31(7):569-80. PMID: 8326772.
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    253. Weissman JS, Kim PS. The pro region of BPTI facilitates folding. Cell. 1992 Nov 27; 71(5):841-51. PMID: 1384990.
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    254. Weissman JS, Gatsonis C, Epstein AM. Rates of avoidable hospitalization by insurance status in Massachusetts and Maryland. JAMA. 1992 Nov 04; 268(17):2388-94. PMID: 1404795.
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    255. Weissman JS, Kim PS. Kinetic role of nonnative species in the folding of bovine pancreatic trypsin inhibitor. Proc Natl Acad Sci U S A. 1992 Oct 15; 89(20):9900-4. PMID: 1384063.
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    256. Stern RS, Weissman JS, Epstein AM. The emergency department as a pathway to admission for poor and high-cost patients. JAMA. 1991 Oct 23-30; 266(16):2238-43. PMID: 1920722.
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    257. Weissman JS, Kim PS. Reexamination of the folding of BPTI: predominance of native intermediates. Science. 1991 Sep 20; 253(5026):1386-93. PMID: 1716783.
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    258. Moore MR, Blatter DD, Weissman J, Tyler HR. Acute aortic thrombosis causing sudden paraplegia in a patient with known thoraco-lumbar spinal metastasis: the diagnostic usefulness of magnetic resonance imaging. Neurosurgery. 1989 Jul; 25(1):105-9. PMID: 2755568.
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    259. Weissman J, Epstein AM. Case mix and resource utilization by uninsured hospital patients in the Boston metropolitan area. JAMA. 1989 Jun 23-30; 261(24):3572-6. PMID: 2498539.
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    260. McAuliffe WE, Santangelo S, Magnuson E, Sobol A, Rohman M, Weissman J. Risk factors of drug impairment in random samples of physicians and medical students. Int J Addict. 1987 Sep; 22(9):825-41. PMID: 3679638.
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    261. Weissman J, Trevor A, Chiba K, Peterson LA, Caldera P, Castagnoli N, Baillie T. Metabolism of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by liver homogenate fractions. J Med Chem. 1985 Aug; 28(8):997-1001. PMID: 3874963.
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