Julius Guccione, PhD
|School||UCSF School of Medicine|
|Address||1657 Scott Str., MZ Bldg E|
San Francisco CA 94115
|University of California, San Diego, CA||1985
||1990||Institutional National Research Service Award|
|Johns Hopkins University, Baltimore, MD||1990
||1991||Institutional National Research Service Award|
||1993||Individual National Research Service Award of the NIH|
|1999||Richard Skalak Best Paper Award of the ASME Bioengineering Division|
Julius M. Guccione, Ph.D. is Professor in Residence in the UCSF Department of Surgery, specializing in realistic simulation of the efficacy of novel surgical procedures and devices for treating ischemic cardiomyopathy. He is the sole PI on an active R01 (HL077921: Virtual Tools for Cardiac Ventricular Remodeling Surgery). He is the contact PI on another active R01 (HL118627: Minimally Invasive Ventricular Polymeric Injection for Treatment of Heart Failure). Additionally, he is the contact PI on an active U01 (HL119578-01A1: Multi-Scale Laws of Myocardial Growth and Remodeling).
Dr. Guccione graduated with a B.S. in Biomedical Engineering from Tulane University. He obtained his M.S. and Ph.D. in Bioengineering from UCSD. He completed a research fellowship in Biomedical Engineering at The Johns Hopkins University.
Dr. Guccione has been the recipient of an individual National Research Service Award (F32HL008492: Ventricular Muscle Mechanics Under Physiological Loading). As an assistant professor of biomedical and mechanical engineering at Washington University in St. Louis, he received a Biomedical Engineering Research Grant (Regional Mechanics of Intact Ventricular Muscle) from the Whitaker Foundation and an R01 (HL058759: Regional Mechanics of Left Ventricular Aneurysm). In 1999 he received the Richard Skalak Best Paper Award of the ASME Bioengineering Division.
My mission at UCSF is to help doctors use realistic simulation to improve the ways they diagnose and treat cardiovascular disease. What if doctors could rely on the same incredible 3D modeling and realistic simulation technology that the aerospace and automotive industries have used for decades to virtually design and test products for optimal performance, reliability and safety? My niche is the development and validation of 3D models of beating human hearts. My students have used those models to realistically simulate the effects of a number of novel surgical procedures and devices on heart function and wall stress, which cannot be measured directly. Last October, in the International Journal of Cardiology we published a study of a novel device that reduced left ventricular wall stress in failing human hearts by 35%! My goal is to use realistic simulation to optimize the design of cardiovascular devices for individual patients.
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