Charles Higgins, MD

Title(s)Professor Emeritus, Radiology
SchoolSchool of Medicine
Address185 Berry Street Bldg B, #B20
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoClinical Fellowship School of Medicine - Radiology
    Collapse Awards and Honors
    American Heart Association2011Distinguished Scientist
    Society of Cardiovascular MR2011Gold Medal
    Radiology Society of North America 2000Outstanding Researcher Award
    University of Pennsylvania Medical Center, Philadelphia1998PA-Pendergrass Lecture
    Canadian Association of Radiologists, Vancouver1990Gordon Richards Memorial Lecture
    Temple University1986Herbert Stauffer Memorial Lecture
    Radiology Society of North America1984New Horizons Lecture Award of Honor

    Collapse Overview 
    Collapse Overview
    Dr. Higgins, MD, is a Professor of Radiology in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He retired January 2012 after over 27 years in the Department of Radiology, but continues to contribute his clinical, research, and teaching skills as a Professor Emeritus. Dr. Higgins obtained his medical degree from Jefferson Medical College in Philadelphia. He completed a residency from the University of California, Los Angeles and a residency from the University of California, San Diego, followed by a fellowship in Cardiovascular Radiology from Stanford University Hospital, California.

    Dr. Higgins is an expert in cardiovascular magnetic resonance imaging, congenital heart disease, ischemic heart disease, acquired heart disease, thoracic aortic disease, and contrast media. He has laboratory research on interventional MRI, which is developing MR guided techniques for transcatheter delivery of aortic and pulmonary valves and aortic stents in pigs and dogs.

    Dr. Higgins has delivered 36 titled lectureships in the Unites States and abroad. He is and has been a member of the editorial boards of 14 scientific journals, and he is currently a member of Circulation, the American Journal of Cardiology, the Journal of American College of Cardiology, the Journal of Magnetic Resonance Imaging, and the Journal of Cardiovascular MR. Dr. Higgins has published 746 articles, and he has written 126 book chapters and 26 books.

    Expertise:
    Cardiac and Pulmonary Imaging

    Specialty:
    Heart and thoracic disease

    Professional Interests:
    Cardiovascular magnetic resonance imaging, congenital heart disease, ischemic heart disease, acquired heart disease, thoracic aortic disease, and contrast media

    Education and Training:
    • Medical School: Jefferson Medical College, Philadelphia
    • Internship: University of California, Los Angeles
    • Residency: University of California, Los Angeles
    • Residency: University of California, San Diego
    • Fellowship: Stanford University Hospital, California - Cardiovascular Radiology

    Collapse Research 
    Collapse Research Activities and Funding
    MYOCARDIAL INJURIES USING MRI
    NIH R01HL052569Aug 1, 1996 - Jul 31, 2000
    Role: Principal Investigator
    RESEARCH TRAINING IN CARDIOVASCULAR IMAGING
    NIH T32HL007570Jul 1, 1984 - Aug 31, 2001
    Role: Principal Investigator
    MR IMAGING ADN SPECTROSCOPY OF ISCHEMIC HEART DISEASE
    NIH R01HL032283Apr 1, 1984 - Jun 30, 1991
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Acute versus Chronic Myocardial Infarction: Diagnostic Accuracy of Quantitative Native T1 and T2 Mapping versus Assessment of Edema on Standard T2-weighted Cardiovascular MR Images for Differentiation. Radiology. 2017 10; 285(1):83-91. Tahir E, Sinn M, Bohnen S, Avanesov M, Säring D, Stehning C, Schnackenburg B, Eulenburg C, Wien J, Radunski UK, Blankenberg S, Adam G, Higgins CB, Saeed M, Muellerleile K, Lund GK. PMID: 28678672.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    2. Assessment of Left Ventricular Enlargement at Multidetector Computed Tomography. J Comput Assist Tomogr. 2015 Sep-Oct; 39(5):794-6. Kathiria NN, Devcic Z, Chen JS, Naeger DM, Hope MD, Higgins CB, Ordovas KG. PMID: 26295194.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    3. Advances in MR imaging assessment of adults with congenital heart disease. Magn Reson Imaging Clin N Am. 2015 Feb; 23(1):35-40. Kathiria NN, Higgins CB, Ordovas KG. PMID: 25476672.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    4. Low-intensity late gadolinium enhancement predominates in hypertrophic cardiomyopathy. Clin Imaging. 2015 May-Jun; 39(3):432-6. Naeger DM, Higgins C, De Marco T, Muzzarelli S, Ordovas KG. PMID: 25724224.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Cardiac radiology: centenary review. Radiology. 2014 Nov; 273(2 Suppl):S142-59. de Roos A, Higgins CB. PMID: 25340434.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    6. CMR assessment of right ventricular function in patients with combined pulmonary stenosis and insufficiency after correction of tetralogy of Fallot. Acta Radiol. 2013 Dec; 54(10):1132-7. Kohi MP, Ordovas KG, Naeger DM, Meadows AK, Foster E, Higgins CB. PMID: 23864059.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Cardiovascular MR imaging after surgical correction of tetralogy of Fallot: approach based on understanding of surgical procedures. Radiographics. 2013 Jul-Aug; 33(4):1037-52. Ordovas KG, Muzzarelli S, Hope MD, Naeger DM, Karl T, Reddy GP, Marchiori E, Higgins CB. PMID: 23842971.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    8. Delayed enhancement magnetic resonance imaging in nonischemic myocardial disease. J Thorac Imaging. 2013 Mar; 28(2):84-92; quiz 93-5. Moraes GL, Higgins CB, Ordovas KG. PMID: 23422782.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Magnetic resonance imaging of hypertrophic cardiomyopathy. J Thorac Imaging. 2013 Jan; 28(1):W12-8. Cannavale A, Ordovás KG, Higgins CB. PMID: 20827222.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Zoonotic infections among employees from Great Smoky Mountains and Rocky Mountain National Parks, 2008-2009. Vector Borne Zoonotic Dis. 2012 Nov; 12(11):922-31. Adjemian J, Weber IB, McQuiston J, Griffith KS, Mead PS, Nicholson W, Roche A, Schriefer M, Fischer M, Kosoy O, Laven JJ, Stoddard RA, Hoffmaster AR, Smith T, Bui D, Wilkins PP, Jones JL, Gupton PN, Quinn CP, Messonnier N, Higgins C, Wong D. PMID: 22835153; PMCID: PMC3533868.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsPHPublic Health
    11. Heart as a source of stroke: imaging evaluation with computed tomography. J Thorac Imaging. 2012 May; 27(3):W52-60. Chung JH, Mitsumori LM, Ordovas KG, Elicker BM, Higgins CB, Reddy GP. PMID: 20811298.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Collateral flow measurement by phase-contrast magnetic resonance imaging for the assessment of systemic venous baffle patency after atrial switch repair for transposition of the great arteries. J Thorac Imaging. 2012 May; 27(3):175-8. Muzzarelli S, Ordovas KG, Higgins CB, Meadows AK. PMID: 22406914.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Potential of delayed gadolinium enhancement magnetic resonance imaging for quantification of reverse remodeling of the peri-infarct zone in patients with ischemic cardiomyopathy treated with chronic vasodilator therapy: initial experience. J Thorac Imaging. 2012 Mar; 27(2):121-4. Muzzarelli S, Ordovas KG, Cannavale G, Naeger D, Michaels AD, Higgins CB. PMID: 21552150; PMCID: PMC3155017.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Usefulness of cardiovascular magnetic resonance imaging to predict the need for intervention in patients with coarctation of the aorta. Am J Cardiol. 2012 Mar 15; 109(6):861-5. Muzzarelli S, Meadows AK, Ordovas KG, Higgins CB, Meadows JJ. PMID: 22196785.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    15. Delayed contrast enhancement on MR images of myocardium: past, present, future. Radiology. 2011 Nov; 261(2):358-74. Ordovas KG, Higgins CB. PMID: 22012903.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimals
    16. Impaired regional left ventricular strain after repair of tetralogy of Fallot. J Magn Reson Imaging. 2012 Jan; 35(1):79-85. Ordovas KG, Carlsson M, Lease KE, Foster E, Meadows AK, Martin AJ, Hope M, Do L, Higgins CB, Saeed M. PMID: 22002841.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. Prediction of hemodynamic severity of coarctation by magnetic resonance imaging. Am J Cardiol. 2011 Nov 01; 108(9):1335-40. Muzzarelli S, Meadows AK, Ordovas KG, Hope MD, Higgins CB, Nielsen JC, Geva T, Meadows JJ. PMID: 21861960.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. 4D flow CMR in assessment of valve-related ascending aortic disease. JACC Cardiovasc Imaging. 2011 Jul; 4(7):781-7. Hope MD, Hope TA, Crook SE, Ordovas KG, Urbania TH, Alley MT, Higgins CB. PMID: 21757170.
      View in: PubMed   Mentions: 110     Fields:    Translation:Humans
    19. Diagnostic value of the flow profile in the distal descending aorta by phase-contrast magnetic resonance for predicting severe coarctation of the aorta. J Magn Reson Imaging. 2011 Jun; 33(6):1440-6. Muzzarelli S, Ordovas KG, Hope MD, Meadows JJ, Higgins CB, Meadows AK. PMID: 21591014.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Cardiovascular MRI for the assessment of heart failure: focus on clinical management and prognosis. J Magn Reson Imaging. 2011 Feb; 33(2):275-86. Muzzarelli S, Ordovas K, Higgins CB. PMID: 21274968.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Tetralogy of Fallot: impact of the excursion of the interventricular septum on left ventricular systolic function and fibrosis after surgical repair. Radiology. 2011 May; 259(2):375-83. Muzzarelli S, Ordovas KG, Cannavale G, Meadows AK, Higgins CB. PMID: 21248236.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    22. Four-dimensional flow magnetic resonance imaging with wall shear stress analysis before and after repair of aortopulmonary fistula. Circ Cardiovasc Imaging. 2010 Nov; 3(6):766-8. Hope MD, Hope TA, Urbania TH, Higgins CB. PMID: 21081744.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. Hypertrophic cardiomyopathy with restrictive phenotype and myocardial crypts. J Thorac Imaging. 2010 Nov; 25(4):W121-3. Cannavale A, Ordovás KG, Rame EJ, Higgins CB. PMID: 20463612.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Unroofing the diagnosis. Int J Cardiovasc Imaging. 2010 Dec; 26(8):841-2. Cannavale G, Higgins CB, Ordovas KG. PMID: 20614189.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns. Radiology. 2010 Apr; 255(1):53-61. Hope MD, Hope TA, Meadows AK, Ordovas KG, Urbania TH, Alley MT, Higgins CB. PMID: 20308444.
      View in: PubMed   Mentions: 141     Fields:    Translation:Humans
    26. Clinical evaluation of aortic coarctation with 4D flow MR imaging. J Magn Reson Imaging. 2010 Mar; 31(3):711-8. Hope MD, Meadows AK, Hope TA, Ordovas KG, Saloner D, Reddy GP, Alley MT, Higgins CB. PMID: 20187217.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    27. Society for Cardiovascular Magnetic Resonance guidelines for reporting cardiovascular magnetic resonance examinations. J Cardiovasc Magn Reson. 2009 Mar 03; 11:5. Hundley WG, Bluemke D, Bogaert JG, Friedrich MG, Higgins CB, Lawson MA, McConnell MV, Raman SV, van Rossum AC, Flamm S, Kramer CM, Nagel E, Neubauer S. PMID: 19257889; PMCID: PMC2662831.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    28. Early use of contrast in cardiac magnetic resonance. JACC Cardiovasc Imaging. 2009 Feb; 2(2):241-4. Higgins CB. PMID: 19356562.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    29. Magnetic resonance imaging as a potential gold standard for infarct quantification. J Electrocardiol. 2008 Nov-Dec; 41(6):614-20. Carlsson M, Arheden H, Higgins CB, Saeed M. PMID: 18817927.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    30. Permanent coronary artery occlusion: cardiovascular MR imaging is platform for percutaneous transendocardial delivery and assessment of gene therapy in canine model. Radiology. 2008 Nov; 249(2):560-71. Saeed M, Martin A, Jacquier A, Bucknor M, Saloner D, Do L, Ursell P, Su H, Kan YW, Higgins CB. PMID: 18780824; PMCID: PMC2657866.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    31. MR assessment of myocardial perfusion, viability, and function after intramyocardial transfer of VM202, a new plasmid human hepatocyte growth factor in ischemic swine myocardium. Radiology. 2008 Oct; 249(1):107-18. Saeed M, Martin A, Ursell P, Do L, Bucknor M, Higgins CB, Saloner D. PMID: 18682582; PMCID: PMC2798089.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    32. Magnetic resonance imaging in the adult with congenital heart disease. Semin Roentgenol. 2008 Jul; 43(3):246-58. Knauth Meadows A, Ordovas K, Higgins CB, Reddy GP. PMID: 18486685.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    33. MRI in nonischemic acquired heart disease. J Magn Reson Imaging. 2008 Jun; 27(6):1195-213. Ordovás KG, Reddy GP, Higgins CB. PMID: 18504737.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Images in cardiovascular medicine. Evaluation of bicuspid aortic valve and aortic coarctation with 4D flow magnetic resonance imaging. Circulation. 2008 May 27; 117(21):2818-9. Hope MD, Meadows AK, Hope TA, Ordovas KG, Reddy GP, Alley MT, Higgins CB. PMID: 18506021.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    35. MR imaging of ischemic heart disease. Magn Reson Imaging Clin N Am. 2008 May; 16(2):201-12, viii. Reddy GP, Pujadas S, Ordovas KG, Higgins CB. PMID: 18474327.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. MR imaging assessment of the kinetics of P846, a new gadolinium-based MR contrast medium, in ischemically injured myocardium. Contrast Media Mol Imaging. 2008 May-Jun; 3(3):112-9. Jacquier A, Wendland M, Do L, Robert P, Corot C, Higgins CB, Saeed M. PMID: 18548477.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    37. P846, a new gadolinium based low diffusion magnetic resonance contrast agent, in characterizing occlusive infarcts, reperfused ischemic myocardium and reperfused infarcts in rats. MAGMA. 2008 May; 21(3):207-18. Jacquier A, Bucknor M, Do L, Robert P, Corot C, Higgins CB, Saeed M. PMID: 18446394.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    38. Left ventricular postmyocardial infarction remodeling studied by combining MR-tagging with delayed MR contrast enhancement. Invest Radiol. 2008 Apr; 43(4):219-28. Mewton N, Croisille P, Revel D, Weber O, Higgins CB, Saeed M. PMID: 18340245.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    39. Injection of adeno-associated viral vector encoding vascular endothelial growth factor gene in infarcted swine myocardium: MR measurements of left ventricular function and strain. Radiology. 2007 Oct; 245(1):196-205. Jacquier A, Higgins CB, Martin AJ, Do L, Saloner D, Saeed M. PMID: 17885189.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    40. Effect of chronic sustained-release dipyridamole on myocardial blood flow and left ventricular function in patients with ischemic cardiomyopathy. Congest Heart Fail. 2007 May-Jun; 13(3):130-5. Akhtar M, Ordovas K, Martin A, Higgins CB, Michaels AD. PMID: 17541306.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    41. Disparity between ratios of diameters and blood flows in central pulmonary arteries in postoperative congenital heart disease using MRI. J Magn Reson Imaging. 2007 Apr; 25(4):721-6. Ordovás KG, Tan C, Reddy GP, Weber OM, Lu Y, Higgins CB. PMID: 17335010.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    42. Adeno-associated viral vector-encoding vascular endothelial growth factor gene: effect on cardiovascular MR perfusion and infarct resorption measurements in swine. Radiology. 2007 May; 243(2):451-60. Saeed M, Saloner D, Martin A, Do L, Weber O, Ursell PC, Jacquier A, Lee R, Higgins CB. PMID: 17384240.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    43. Images in cardiovascular medicine. Magnetic resonance imaging of a posttraumatic myocardial infarction and ventricular septal defect with a closure device in place. Circulation. 2007 Jan 16; 115(2):e13-5. Jun SL, Chanani NK, Moore P, Higgins CB. PMID: 17228006.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. MR imaging in assessing cardiovascular interventions and myocardial injury. Contrast Media Mol Imaging. 2007 Jan-Feb; 2(1):1-15. Jacquier A, Higgins CB, Saeed M. PMID: 17326039.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. Guidelines for training in Cardiovascular Magnetic Resonance (CMR). J Cardiovasc Magn Reson. 2007; 9(1):3-4. Kim RJ, de Roos A, Fleck E, Higgins CB, Pohost GM, Prince M, Manning WJ, Society for Cardiovascular Magnetic Resonance (SCMR) Clinical Practice Committee. PMID: 17178674.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    46. Discrimination of myocardial acute and chronic (scar) infarctions on delayed contrast enhanced magnetic resonance imaging with intravascular magnetic resonance contrast media. J Am Coll Cardiol. 2006 Nov 21; 48(10):1961-8. Saeed M, Weber O, Lee R, Do L, Martin A, Saloner D, Ursell P, Robert P, Corot C, Higgins CB. PMID: 17112985.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    47. ACR practice guideline for the performance and interpretation of cardiac magnetic resonance imaging (MRI). J Am Coll Radiol. 2006 Sep; 3(9):665-76. Woodard PK, Bluemke DA, Cascade PN, Finn JP, Stillman AE, Higgins CB, White RD, Yucel EK, American College of Radiology. PMID: 17412147.
      View in: PubMed   Mentions: 28     Fields:    
    48. Delivery and assessment of endovascular stents to repair aortic coarctation using MR and X-ray imaging. J Magn Reson Imaging. 2006 Aug; 24(2):371-8. Saeed M, Henk CB, Weber O, Martin A, Wilson M, Shunk K, Saloner D, Higgins CB. PMID: 16786568.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    49. Phase contrast MR imaging to measure changes in collateral blood flow after stenting of recurrent aortic coarctation: initial experience. J Magn Reson Imaging. 2006 Jul; 24(1):72-6. Pujadas S, Reddy GP, Weber O, Tan C, Moore P, Higgins CB. PMID: 16755530.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    50. MR guidance of targeted injections into border and core of scarred myocardium in pigs. Radiology. 2006 Aug; 240(2):419-26. Saeed M, Martin AJ, Lee RJ, Weber O, Revel D, Saloner D, Higgins CB. PMID: 16801371.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    51. Meeting highlights of the 9th annual scientific sessions of the society for cardiovascular magnetic resonance: Miami, Florida, January 20-22, 2006. J Am Coll Cardiol. 2006 Jul 04; 48(1):187-92. Kramer CM, Neubauer S, Kraitchman D, Higgins CB, Fogel MA, Friedrich MG, Manning WJ. PMID: 16814666.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. MR evaluation of cardiovascular physiology in congenital heart disease: flow and function. J Cardiovasc Magn Reson. 2006; 8(4):607-17. Weber OM, Higgins CB. PMID: 16869313.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    53. Scarred myocardium imposes additional burden on remote viable myocardium despite a reduction in the extent of area with late contrast MR enhancement. Eur Radiol. 2006 Apr; 16(4):827-36. Saeed M, Lee RJ, Weber O, Do L, Martin A, Ursell P, Saloner D, Higgins CB. PMID: 16362420.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    54. Endovascular interventional MRI. J Magn Reson Imaging. 2005 Oct; 22(4):451-60. Henk CB, Higgins CB, Saeed M. PMID: 16161076.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    55. Meeting highlights of the 8th Annual Scientific Sessions of the Society For Cardiovascular Magnetic Resonance, January 21 to 23, 2005. J Am Coll Cardiol. 2005 Aug 02; 46(3):411-6. Kramer CM, Friedrich MG, Neubauer S, Stuber M, Geva T, Higgins CB, Manning WJ. PMID: 16053951.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    56. Gadomer-enhanced MR imaging in the detection of microvascular obstruction: alleviation with nicorandil therapy. Radiology. 2005 Aug; 236(2):510-8. Krombach GA, Higgins CB, Chujo M, Saeed M. PMID: 16040908.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    57. Combined pulmonary stenosis and insufficiency preserves myocardial contractility in the developing heart of growing swine at midterm follow-up. J Appl Physiol (1985). 2005 Oct; 99(4):1422-7. Kuehne T, Gleason BK, Saeed M, Turner D, Weil J, Teitel DF, Higgins CB, Moore P. PMID: 15976362.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    58. Imaging findings in Takayasu's arteritis. AJR Am J Roentgenol. 2005 Jun; 184(6):1945-50. Gotway MB, Araoz PA, Macedo TA, Stanson AW, Higgins CB, Ring EJ, Dawn SK, Webb WR, Leung JW, Reddy GP. PMID: 15908559.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    59. Long-term oral treatment with nicorandil prevents the progression of left ventricular hypertrophy and preserves viability. J Cardiovasc Pharmacol. 2005 Apr; 45(4):333-40. Schalla S, Higgins CB, Saeed M. PMID: 15772522.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    60. Myocardial blood flow in patients with dilated cardiomyopathy: quantitative assessment with velocity-encoded cine magnetic resonance imaging of the coronary sinus. J Magn Reson Imaging. 2005 Apr; 21(4):347-53. Watzinger N, Lund GK, Saeed M, Reddy GP, Araoz PA, Yang M, Schwartz AB, Bedigian M, Higgins CB. PMID: 15778950.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    61. Balloon sizing and transcatheter closure of acute atrial septal defects guided by magnetic resonance fluoroscopy: assessment and validation in a large animal model. J Magn Reson Imaging. 2005 Mar; 21(3):204-11. Schalla S, Saeed M, Higgins CB, Weber O, Martin A, Moore P. PMID: 15723375.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    62. Magnetic resonance imaging-guided transcatheter implantation of a prosthetic valve in aortic valve position: Feasibility study in swine. J Am Coll Cardiol. 2004 Dec 07; 44(11):2247-9. Kuehne T, Yilmaz S, Meinus C, Moore P, Saeed M, Weber O, Higgins CB, Blank T, Elsaesser E, Schnackenburg B, Ewert P, Lange PE, Nagel E. PMID: 15582324.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    63. Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. Eur Heart J. 2004 Nov; 25(21):1940-65. Pennell DJ, Sechtem UP, Higgins CB, Manning WJ, Pohost GM, Rademakers FE, van Rossum AC, Shaw LJ, Yucel EK, Society for Cardiovascular Magnetic Resonance, Working Group on Cardiovascular Magnetic Resonance of the European Society of Cardiology. PMID: 15522474.
      View in: PubMed   Mentions: 199     Fields:    Translation:Humans
    64. Magnetic resonance imaging analysis of right ventricular pressure-volume loops: in vivo validation and clinical application in patients with pulmonary hypertension. Circulation. 2004 Oct 05; 110(14):2010-6. Kuehne T, Yilmaz S, Steendijk P, Moore P, Groenink M, Saaed M, Weber O, Higgins CB, Ewert P, Fleck E, Nagel E, Schulze-Neick I, Lange P. PMID: 15451801.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimals
    65. Magnetic resonance imaging in myocardial ischemia. Curr Opin Cardiol. 2004 Sep; 19(5):510-6. Viswamitra S, Higgins CB, Meacham DF, Mehta JL. PMID: 15316461.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    66. Free-breathing, three-dimensional coronary artery magnetic resonance angiography: comparison of sequences. J Magn Reson Imaging. 2004 Sep; 20(3):395-402. Weber OM, Pujadas S, Martin AJ, Higgins CB. PMID: 15332246.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    67. Effect of potassium-channel opener therapy on reperfused infarction in hypertrophied hearts: demonstration of preconditioning by using functional and contrast-enhanced magnetic resonance imaging. J Cardiovasc Pharmacol Ther. 2004 Sep; 9(3):193-202. Schalla S, Higgins CB, Chujo M, Saeed M. PMID: 15378140.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    68. MR imaging assessment of cardiac function. J Magn Reson Imaging. 2004 Jun; 19(6):789-99. Pujadas S, Reddy GP, Weber O, Lee JJ, Higgins CB. PMID: 15170784.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    69. Transendocardial delivery of extracellular myocardial markers by using combination X-ray/MR fluoroscopic guidance: feasibility study in dogs. Radiology. 2004 Jun; 231(3):689-96. Saeed M, Lee R, Martin A, Weber O, Krombach GA, Schalla S, Lee M, Saloner D, Higgins CB. PMID: 15163809.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    70. Acute myocardial infarction: evaluation with first-pass enhancement and delayed enhancement MR imaging compared with 201Tl SPECT imaging. Radiology. 2004 Jul; 232(1):49-57. Lund GK, Stork A, Saeed M, Bansmann MP, Gerken JH, Müller V, Mester J, Higgins CB, Adam G, Meinertz T. PMID: 15166320.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    71. Accentuation of high susceptibility of hypertrophied myocardium to ischemia: complementary assessment of Gadophrin-enhancement and left ventricular function with MRI. Magn Reson Med. 2004 Mar; 51(3):552-8. Schalla S, Wendland MF, Higgins CB, Ebert W, Saeed M. PMID: 15004797.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    72. Malignant pleural mesothelioma: evaluation with CT, MR imaging, and PET. Radiographics. 2004 Jan-Feb; 24(1):105-19. Wang ZJ, Reddy GP, Gotway MB, Higgins CB, Jablons DM, Ramaswamy M, Hawkins RA, Webb WR. PMID: 14730040.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    73. Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. J Cardiovasc Magn Reson. 2004; 6(4):727-65. Pennell DJ, Sechtem UP, Higgins CB, Manning WJ, Pohost GM, Rademakers FE, van Rossum AC, Shaw LJ, Yucel EK, European Society of cardiology, Soceity for Cardiovascular Magnetic Resonance. PMID: 15646878.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    74. Contrast-enhanced MR delineation of stunned myocardium with administration of MnCl(2) in rats. Radiology. 2004 Jan; 230(1):183-90. Krombach GA, Saeed M, Higgins CB, Novikov V, Wendland MF. PMID: 14695393.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    75. Comparison of late enhancement cardiovascular magnetic resonance and thallium SPECT in patients with coronary disease and left ventricular dysfunction. J Cardiovasc Magn Reson. 2004; 6(2):549-56. Ansari M, Araoz PA, Gerard SK, Watzinger N, Lund GK, Massie BM, Higgins CB, Saloner DA. PMID: 15137339.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    76. Whole-heart steady-state free precession coronary artery magnetic resonance angiography. Magn Reson Med. 2003 Dec; 50(6):1223-8. Weber OM, Martin AJ, Higgins CB. PMID: 14648570.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    77. Distribution of intramyocardially injected extracellular MR contrast medium: effects of concentration and volume. Eur Radiol. 2004 Feb; 14(2):334-40. Krombach GA, Baireuther R, Higgins CB, Saeed M. PMID: 14618368.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    78. Effects of pulmonary insufficiency on biventricular function in the developing heart of growing swine. Circulation. 2003 Oct 21; 108(16):2007-13. Kuehne T, Saeed M, Gleason K, Turner D, Teitel D, Higgins CB, Moore P. PMID: 14557371.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    79. Helical CT pulmonary angiography predictors of in-hospital morbidity and mortality in patients with acute pulmonary embolism. J Thorac Imaging. 2003 Oct; 18(4):207-16. Araoz PA, Gotway MB, Trowbridge RL, Bailey RA, Auerbach AD, Reddy GP, Dawn SK, Webb WR, Higgins CB. PMID: 14561905.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    80. Magnetic resonance imaging of congenital heart disease: evaluation of morphology and function. Semin Roentgenol. 2003 Oct; 38(4):342-51. Reddy GP, Higgins CB. PMID: 14621376.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    81. Magnetic resonance imaging in ischemic heart disease. Semin Roentgenol. 2003 Oct; 38(4):320-9. Pujadas S, Reddy GP, Lee JJ, Higgins CB. PMID: 14621374.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    82. Interventional cardiac magnetic resonance imaging. Semin Roentgenol. 2003 Oct; 38(4):352-7. Weber OM, Schalla S, Martin AJ, Saeed M, Lee R, Shunk KA, Moore P, Higgins CB. PMID: 14621377.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    83. CT and MR imaging of pericardial disease. Radiographics. 2003 Oct; 23 Spec No:S167-80. Wang ZJ, Reddy GP, Gotway MB, Yeh BM, Hetts SW, Higgins CB. PMID: 14557510.
      View in: PubMed   Mentions: 91     Fields:    Translation:Humans
    84. Cardiovascular shunts: MR imaging evaluation. Radiographics. 2003 Oct; 23 Spec No:S181-94. Wang ZJ, Reddy GP, Gotway MB, Yeh BM, Higgins CB. PMID: 14557511.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    85. Magnetic resonance--guided cardiac catheterization in a swine model of atrial septal defect. Circulation. 2003 Oct 14; 108(15):1865-70. Schalla S, Saeed M, Higgins CB, Martin A, Weber O, Moore P. PMID: 14517162.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    86. Chronic heart failure: global left ventricular perfusion and coronary flow reserve with velocity-encoded cine MR imaging: initial results. Radiology. 2003 Apr; 227(1):209-15. Lund GK, Watzinger N, Saeed M, Reddy GP, Yang M, Araoz PA, Curatola D, Bedigian M, Higgins CB. PMID: 12668746.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    87. Endovascular stents in pulmonary valve and artery in swine: feasibility study of MR imaging-guided deployment and postinterventional assessment. Radiology. 2003 Feb; 226(2):475-81. Kuehne T, Saeed M, Higgins CB, Gleason K, Krombach GA, Weber OM, Martin AJ, Turner D, Teitel D, Moore P. PMID: 12563142.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    88. MR imaging of hepatic pulmonary fusion in neonates. AJR Am J Roentgenol. 2003 Feb; 180(2):438-40. Keller RL, Aaroz PA, Hawgood S, Higgins CB. PMID: 12540449.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    89. MR findings of collateral circulation are more accurate measures of hemodynamic significance than arm-leg blood pressure gradient after repair of coarctation of the aorta. J Magn Reson Imaging. 2003 Feb; 17(2):177-83. Araoz PA, Reddy GP, Tarnoff H, Roge CL, Higgins CB. PMID: 12541224.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    90. MR Imaging of arrhythmogenic right ventricular cardiomyopathy: morphologic findings and interobserver reliability. Cardiology. 2003; 99(3):153-62. Bluemke DA, Krupinski EA, Ovitt T, Gear K, Unger E, Axel L, Boxt LM, Casolo G, Ferrari VA, Funaki B, Globits S, Higgins CB, Julsrud P, Lipton M, Mawson J, Nygren A, Pennell DJ, Stillman A, White RD, Wichter T, Marcus F. PMID: 12824723.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    91. The potential of contrast-enhanced magnetic resonance imaging for predicting left ventricular remodeling. J Magn Reson Imaging. 2002 Dec; 16(6):633-40. Watzinger N, Lund GK, Higgins CB, Wendland MF, Weinmann HJ, Saeed M. PMID: 12451576.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    92. MR imaging of spatial extent of microvascular injury in reperfused ischemically injured rat myocardium: value of blood pool ultrasmall superparamagnetic particles of iron oxide. Radiology. 2002 Nov; 225(2):479-86. Krombach GA, Wendland MF, Higgins CB, Saeed M. PMID: 12409583.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    93. MR portal venography: preliminary results of fast acquisition without contrast material or breath holding. Acad Radiol. 2002 Oct; 9(10):1179-84. Wilson MW, LaBerge JM, Kerlan RK, Martin AJ, Weber OM, Roberts T, Vitalich C, Higgins CB, Gordon RL. PMID: 12385512.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    94. Left ventricular remodeling after infarction: sequential MR imaging with oral nicorandil therapy in rat model. Radiology. 2002 Sep; 224(3):830-7. Saeed M, Watzinger N, Krombach GA, Lund GK, Wendland MF, Chujo M, Higgins CB. PMID: 12202722.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    95. Hyperfunctioning parathyroid tissue: spectrum of appearances on noninvasive imaging. AJR Am J Roentgenol. 2002 Aug; 179(2):495-502. Gotway MB, Leung JW, Gooding GA, Litt HI, Reddy GP, Morita ET, Webb WR, Clark OH, Higgins CB. PMID: 12130462.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    96. Contrast enhanced MRI of stunned myocardium using Mn-based MRI contrast media. Acad Radiol. 2002 Aug; 9 Suppl 2:S341-2. Wendland MF, Krombach GA, Higgins CB, Novikov V, Saeed M. PMID: 12188269.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    97. Quantification of flow dynamics in congenital heart disease: applications of velocity-encoded cine MR imaging. Radiographics. 2002 Jul-Aug; 22(4):895-905; discussion 905-6. Varaprasathan GA, Araoz PA, Higgins CB, Reddy GP. PMID: 12110719.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    98. Blood pool contrast-enhanced MRI detects suppression of microvascular permeability in early postinfarction reperfusion after nicorandil therapy. Magn Reson Med. 2002 May; 47(5):896-902. Krombach GA, Higgins CB, Chujo M, Saeed M. PMID: 11979568.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    99. Influence of blood-pool contrast media on MR imaging and flow measurements in the presence of pulmonary arterial stents in swine. Radiology. 2002 May; 223(2):439-45. Kuehne T, Saeed M, Moore P, Gleason K, Reddy G, Teitel D, Higgins CB. PMID: 11997550.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    100. Thallium-like test for myocardial viability with MnDPDP-enhanced MRI. Acad Radiol. 2002 May; 9 Suppl 1:S82-3. Wendland MF, Saeed M, Bremerich J, Arheden H, Higgins CB. PMID: 12019904.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    101. Assessment of myocardial viability using standard extracellular and necrosis specific MR contrast media. Acad Radiol. 2002 May; 9 Suppl 1:S84-7. Saeed M, Wendland MF, Bremerich GL, Weinmann HJ, Higgins CB. PMID: 12019905.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    102. Noninvasive assessment of the effects of nicorandil on left ventricular volumes and function in reperfused myocardial infarction. Cardiovasc Res. 2002 Apr; 54(1):77-84. Watzinger N, Lund GK, Higgins CB, Chujo M, Saeed M. PMID: 12062364.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    103. A waterborne outbreak of Escherichia coli O157:H7 infections and hemolytic uremic syndrome: implications for rural water systems. Emerg Infect Dis. 2002 Apr; 8(4):370-5. Olsen SJ, Miller G, Breuer T, Kennedy M, Higgins C, Walford J, McKee G, Fox K, Bibb W, Mead P. PMID: 11971769; PMCID: PMC2730238.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCellsPHPublic Health
    104. Images in cardiovascular medicine. Magnetic resonance angiography of criss-cross heart. Circulation. 2002 Jan 29; 105(4):537-8. Araoz PA, Reddy GP, Thomson PD, Higgins CB. PMID: 11815440.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    105. Contrast agents for cardiovascular magnetic resonance imaging. Current status and future directions. Drugs R D. 2002; 3(5):285-302. Schalla S, Higgins CB, Saeed M. PMID: 12455148.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
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