Loading...

Charles Higgins, MD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentRadiology
Address505 Parnassus Avenue
San Francisco CA 94117
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoClinical Fellowship School of Medicine - Radiology
    Collapse Awards and Honors
    American Heart Association2011Distinguished Scientist
    Society of Cardiovascular MR2011Gold Medal
    Radiology Society of North America 2000Outstanding Researcher Award
    University of Pennsylvania Medical Center, Philadelphia1998PA-Pendergrass Lecture
    Canadian Association of Radiologists, Vancouver1990Gordon Richards Memorial Lecture
    Temple University1986Herbert Stauffer Memorial Lecture
    Radiology Society of North America1984New Horizons Lecture Award of Honor

    Collapse Overview 
    Collapse Overview
    Dr. Higgins, MD, is a Professor of Radiology in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He retired January 2012 after over 27 years in the Department of Radiology, but continues to contribute his clinical, research, and teaching skills as a Professor Emeritus. Dr. Higgins obtained his medical degree from Jefferson Medical College in Philadelphia. He completed a residency from the University of California, Los Angeles and a residency from the University of California, San Diego, followed by a fellowship in Cardiovascular Radiology from Stanford University Hospital, California.

    Dr. Higgins is an expert in cardiovascular magnetic resonance imaging, congenital heart disease, ischemic heart disease, acquired heart disease, thoracic aortic disease, and contrast media. He has laboratory research on interventional MRI, which is developing MR guided techniques for transcatheter delivery of aortic and pulmonary valves and aortic stents in pigs and dogs.

    Dr. Higgins has delivered 36 titled lectureships in the Unites States and abroad. He is and has been a member of the editorial boards of 14 scientific journals, and he is currently a member of Circulation, the American Journal of Cardiology, the Journal of American College of Cardiology, the Journal of Magnetic Resonance Imaging, and the Journal of Cardiovascular MR. Dr. Higgins has published 746 articles, and he has written 126 book chapters and 26 books.

    Expertise:
    Cardiac and Pulmonary Imaging

    Specialty:
    Heart and thoracic disease

    Professional Interests:
    Cardiovascular magnetic resonance imaging, congenital heart disease, ischemic heart disease, acquired heart disease, thoracic aortic disease, and contrast media

    Education and Training:
    • Medical School: Jefferson Medical College, Philadelphia
    • Internship: University of California, Los Angeles
    • Residency: University of California, Los Angeles
    • Residency: University of California, San Diego
    • Fellowship: Stanford University Hospital, California - Cardiovascular Radiology


    Collapse Research 
    Collapse Research Activities and Funding
    MYOCARDIAL INJURIES USING MRI
    NIH/NHLBI R01HL052569Aug 1, 1996 - Jul 31, 2000
    Role: Principal Investigator
    RESEARCH TRAINING IN CARDIOVASCULAR IMAGING
    NIH/NHLBI T32HL007570Jul 1, 1984 - Aug 31, 2001
    Role: Principal Investigator
    MR IMAGING ADN SPECTROSCOPY OF ISCHEMIC HEART DISEASE
    NIH/NHLBI R01HL032283Apr 1, 1984 - Jun 30, 1991
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Tahir E, Sinn M, Bohnen S, Avanesov M, Säring D, Stehning C, Schnackenburg B, Eulenburg C, Wien J, Radunski UK, Blankenberg S, Adam G, Higgins C, Saeed M, Muellerleile K, Lund GK. Acute versus Chronic Myocardial Infarction: Diagnostic Accuracy of Quantitative Native T1 and T2 Mapping versus Assessment of Edema on Standard T2-weighted Cardiovascular MR Images for Differentiation. Radiology. 2017 10; 285(1):83-91. PMID: 28678672.
      View in: PubMed
    2. Kathiria NN, Devcic Z, Chen JS, Naeger DM, Hope MD, Higgins C, Ordovas KG. Assessment of Left Ventricular Enlargement at Multidetector Computed Tomography. J Comput Assist Tomogr. 2015 Sep-Oct; 39(5):794-6. PMID: 26295194.
      View in: PubMed
    3. Kathiria NN, Higgins C, Ordovas KG. Advances in MR imaging assessment of adults with congenital heart disease. Magn Reson Imaging Clin N Am. 2015 Feb; 23(1):35-40. PMID: 25476672.
      View in: PubMed
    4. Naeger DM, Higgins C, De Marco T, Muzzarelli S, Ordovas KG. Low-intensity late gadolinium enhancement predominates in hypertrophic cardiomyopathy. Clin Imaging. 2015 May-Jun; 39(3):432-6. PMID: 25724224.
      View in: PubMed
    5. de Roos A, Higgins C. Cardiac radiology: centenary review. Radiology. 2014 Nov; 273(2 Suppl):S142-59. PMID: 25340434.
      View in: PubMed
    6. Kohi MP, Ordovas KG, Naeger DM, Meadows AK, Foster E, Higgins C. CMR assessment of right ventricular function in patients with combined pulmonary stenosis and insufficiency after correction of tetralogy of Fallot. Acta Radiol. 2013 Dec; 54(10):1132-7. PMID: 23864059.
      View in: PubMed
    7. Ordovas KG, Muzzarelli S, Hope MD, Naeger DM, Karl T, Reddy GP, Marchiori E, Higgins C. Cardiovascular MR imaging after surgical correction of tetralogy of Fallot: approach based on understanding of surgical procedures. Radiographics. 2013 Jul-Aug; 33(4):1037-52. PMID: 23842971.
      View in: PubMed
    8. Moraes GL, Higgins C, Ordovas KG. Delayed enhancement magnetic resonance imaging in nonischemic myocardial disease. J Thorac Imaging. 2013 Mar; 28(2):84-92; quiz 93-5. PMID: 23422782.
      View in: PubMed
    9. Cannavale A, Ordovás KG, Higgins C. Magnetic resonance imaging of hypertrophic cardiomyopathy. J Thorac Imaging. 2013 Jan; 28(1):W12-8. PMID: 20827222.
      View in: PubMed
    10. Adjemian J, Weber IB, McQuiston J, Griffith KS, Mead PS, Nicholson W, Roche A, Schriefer M, Fischer M, Kosoy O, Laven JJ, Stoddard RA, Hoffmaster AR, Smith T, Bui D, Wilkins PP, Jones JL, Gupton PN, Quinn CP, Messonnier N, Higgins C, Wong D. Zoonotic infections among employees from Great Smoky Mountains and Rocky Mountain National Parks, 2008-2009. Vector Borne Zoonotic Dis. 2012 Nov; 12(11):922-31. PMID: 22835153; PMCID: PMC3533868.
    11. Chung JH, Mitsumori LM, Ordovas KG, Elicker BM, Higgins C, Reddy GP. Heart as a source of stroke: imaging evaluation with computed tomography. J Thorac Imaging. 2012 May; 27(3):W52-60. PMID: 20811298.
      View in: PubMed
    12. Muzzarelli S, Ordovas KG, Higgins C, Meadows AK. Collateral flow measurement by phase-contrast magnetic resonance imaging for the assessment of systemic venous baffle patency after atrial switch repair for transposition of the great arteries. J Thorac Imaging. 2012 May; 27(3):175-8. PMID: 22406914.
      View in: PubMed
    13. Muzzarelli S, Ordovas KG, Cannavale G, Naeger D, Michaels AD, Higgins C. Potential of delayed gadolinium enhancement magnetic resonance imaging for quantification of reverse remodeling of the peri-infarct zone in patients with ischemic cardiomyopathy treated with chronic vasodilator therapy: initial experience. J Thorac Imaging. 2012 Mar; 27(2):121-4. PMID: 21552150; PMCID: PMC3155017.
    14. Muzzarelli S, Meadows AK, Ordovas KG, Higgins C, Meadows JJ. Usefulness of cardiovascular magnetic resonance imaging to predict the need for intervention in patients with coarctation of the aorta. Am J Cardiol. 2012 Mar 15; 109(6):861-5. PMID: 22196785.
      View in: PubMed
    15. Ordovas KG, Higgins C. Delayed contrast enhancement on MR images of myocardium: past, present, future. Radiology. 2011 Nov; 261(2):358-74. PMID: 22012903.
      View in: PubMed
    16. Ordovas KG, Carlsson M, Lease KE, Foster E, Meadows AK, Martin AJ, Hope M, Do L, Higgins C, Saeed M. Impaired regional left ventricular strain after repair of tetralogy of Fallot. J Magn Reson Imaging. 2012 Jan; 35(1):79-85. PMID: 22002841.
      View in: PubMed
    17. Muzzarelli S, Meadows AK, Ordovas KG, Hope MD, Higgins C, Nielsen JC, Geva T, Meadows JJ. Prediction of hemodynamic severity of coarctation by magnetic resonance imaging. Am J Cardiol. 2011 Nov 01; 108(9):1335-40. PMID: 21861960.
      View in: PubMed
    18. Hope MD, Hope TA, Crook SE, Ordovas KG, Urbania TH, Alley MT, Higgins C. 4D flow CMR in assessment of valve-related ascending aortic disease. JACC Cardiovasc Imaging. 2011 Jul; 4(7):781-7. PMID: 21757170.
      View in: PubMed
    19. Muzzarelli S, Ordovas KG, Hope MD, Meadows JJ, Higgins C, Meadows AK. Diagnostic value of the flow profile in the distal descending aorta by phase-contrast magnetic resonance for predicting severe coarctation of the aorta. J Magn Reson Imaging. 2011 Jun; 33(6):1440-6. PMID: 21591014.
      View in: PubMed
    20. Muzzarelli S, Ordovas K, Higgins C. Cardiovascular MRI for the assessment of heart failure: focus on clinical management and prognosis. J Magn Reson Imaging. 2011 Feb; 33(2):275-86. PMID: 21274968.
      View in: PubMed
    21. Muzzarelli S, Ordovas KG, Cannavale G, Meadows AK, Higgins C. Tetralogy of Fallot: impact of the excursion of the interventricular septum on left ventricular systolic function and fibrosis after surgical repair. Radiology. 2011 May; 259(2):375-83. PMID: 21248236.
      View in: PubMed
    22. Hope MD, Hope TA, Urbania TH, Higgins C. Four-dimensional flow magnetic resonance imaging with wall shear stress analysis before and after repair of aortopulmonary fistula. Circ Cardiovasc Imaging. 2010 Nov; 3(6):766-8. PMID: 21081744.
      View in: PubMed
    23. Cannavale A, Ordovás KG, Rame EJ, Higgins C. Hypertrophic cardiomyopathy with restrictive phenotype and myocardial crypts. J Thorac Imaging. 2010 Nov; 25(4):W121-3. PMID: 20463612.
      View in: PubMed
    24. Cannavale G, Higgins C, Ordovas KG. Unroofing the diagnosis. Int J Cardiovasc Imaging. 2010 Dec; 26(8):841-2. PMID: 20614189.
      View in: PubMed
    25. Hope MD, Hope TA, Meadows AK, Ordovas KG, Urbania TH, Alley MT, Higgins C. Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns. Radiology. 2010 Apr; 255(1):53-61. PMID: 20308444.
      View in: PubMed
    26. Hope MD, Meadows AK, Hope TA, Ordovas KG, Saloner D, Reddy GP, Alley MT, Higgins C. Clinical evaluation of aortic coarctation with 4D flow MR imaging. J Magn Reson Imaging. 2010 Mar; 31(3):711-8. PMID: 20187217.
      View in: PubMed
    27. Hundley WG, Bluemke D, Bogaert JG, Friedrich MG, Higgins C, Lawson MA, McConnell MV, Raman SV, van Rossum AC, Flamm S, Kramer CM, Nagel E, Neubauer S. Society for Cardiovascular Magnetic Resonance guidelines for reporting cardiovascular magnetic resonance examinations. J Cardiovasc Magn Reson. 2009 Mar 03; 11:5. PMID: 19257889.
      View in: PubMed
    28. Higgins C. Early use of contrast in cardiac magnetic resonance. JACC Cardiovasc Imaging. 2009 Feb; 2(2):241-4. PMID: 19356562.
      View in: PubMed
    29. Carlsson M, Arheden H, Higgins C, Saeed M. Magnetic resonance imaging as a potential gold standard for infarct quantification. J Electrocardiol. 2008 Nov-Dec; 41(6):614-20. PMID: 18817927.
      View in: PubMed
    30. Saeed M, Martin A, Jacquier A, Bucknor M, Saloner D, Do L, Ursell P, Su H, Kan YW, Higgins C. Permanent coronary artery occlusion: cardiovascular MR imaging is platform for percutaneous transendocardial delivery and assessment of gene therapy in canine model. Radiology. 2008 Nov; 249(2):560-71. PMID: 18780824; PMCID: PMC2657866.
    31. Saeed M, Martin A, Ursell P, Do L, Bucknor M, Higgins C, Saloner D. MR assessment of myocardial perfusion, viability, and function after intramyocardial transfer of VM202, a new plasmid human hepatocyte growth factor in ischemic swine myocardium. Radiology. 2008 Oct; 249(1):107-18. PMID: 18682582; PMCID: PMC2798089.
    32. Knauth Meadows A, Ordovas K, Higgins C, Reddy GP. Magnetic resonance imaging in the adult with congenital heart disease. Semin Roentgenol. 2008 Jul; 43(3):246-58. PMID: 18486685.
      View in: PubMed
    33. Ordovás KG, Reddy GP, Higgins C. MRI in nonischemic acquired heart disease. J Magn Reson Imaging. 2008 Jun; 27(6):1195-213. PMID: 18504737.
      View in: PubMed
    34. Hope MD, Meadows AK, Hope TA, Ordovas KG, Reddy GP, Alley MT, Higgins C. Images in cardiovascular medicine. Evaluation of bicuspid aortic valve and aortic coarctation with 4D flow magnetic resonance imaging. Circulation. 2008 May 27; 117(21):2818-9. PMID: 18506021.
      View in: PubMed
    35. Reddy GP, Pujadas S, Ordovas KG, Higgins C. MR imaging of ischemic heart disease. Magn Reson Imaging Clin N Am. 2008 May; 16(2):201-12, viii. PMID: 18474327.
      View in: PubMed
    36. Jacquier A, Wendland M, Do L, Robert P, Corot C, Higgins C, Saeed M. MR imaging assessment of the kinetics of P846, a new gadolinium-based MR contrast medium, in ischemically injured myocardium. Contrast Media Mol Imaging. 2008 May-Jun; 3(3):112-9. PMID: 18548477.
      View in: PubMed
    37. Jacquier A, Bucknor M, Do L, Robert P, Corot C, Higgins C, Saeed M. P846, a new gadolinium based low diffusion magnetic resonance contrast agent, in characterizing occlusive infarcts, reperfused ischemic myocardium and reperfused infarcts in rats. MAGMA. 2008 May; 21(3):207-18. PMID: 18446394.
      View in: PubMed
    38. Mewton N, Croisille P, Revel D, Weber O, Higgins C, Saeed M. Left ventricular postmyocardial infarction remodeling studied by combining MR-tagging with delayed MR contrast enhancement. Invest Radiol. 2008 Apr; 43(4):219-28. PMID: 18340245.
      View in: PubMed
    39. Jacquier A, Higgins C, Martin AJ, Do L, Saloner D, Saeed M. Injection of adeno-associated viral vector encoding vascular endothelial growth factor gene in infarcted swine myocardium: MR measurements of left ventricular function and strain. Radiology. 2007 Oct; 245(1):196-205. PMID: 17885189.
      View in: PubMed
    40. Akhtar M, Ordovas K, Martin A, Higgins C, Michaels AD. Effect of chronic sustained-release dipyridamole on myocardial blood flow and left ventricular function in patients with ischemic cardiomyopathy. Congest Heart Fail. 2007 May-Jun; 13(3):130-5. PMID: 17541306.
      View in: PubMed
    41. Ordovás KG, Tan C, Reddy GP, Weber OM, Lu Y, Higgins C. Disparity between ratios of diameters and blood flows in central pulmonary arteries in postoperative congenital heart disease using MRI. J Magn Reson Imaging. 2007 Apr; 25(4):721-6. PMID: 17335010.
      View in: PubMed
    42. Saeed M, Saloner D, Martin A, Do L, Weber O, Ursell PC, Jacquier A, Lee R, Higgins C. Adeno-associated viral vector-encoding vascular endothelial growth factor gene: effect on cardiovascular MR perfusion and infarct resorption measurements in swine. Radiology. 2007 May; 243(2):451-60. PMID: 17384240.
      View in: PubMed
    43. Jun SL, Chanani NK, Moore P, Higgins C. Images in cardiovascular medicine. Magnetic resonance imaging of a posttraumatic myocardial infarction and ventricular septal defect with a closure device in place. Circulation. 2007 Jan 16; 115(2):e13-5. PMID: 17228006.
      View in: PubMed
    44. Jacquier A, Higgins C, Saeed M. MR imaging in assessing cardiovascular interventions and myocardial injury. Contrast Media Mol Imaging. 2007 Jan-Feb; 2(1):1-15. PMID: 17326039.
      View in: PubMed
    45. Kim RJ, de Roos A, Fleck E, Higgins C, Pohost GM, Prince M, Manning WJ. Guidelines for training in Cardiovascular Magnetic Resonance (CMR). J Cardiovasc Magn Reson. 2007; 9(1):3-4. PMID: 17178674.
      View in: PubMed
    46. Saeed M, Weber O, Lee R, Do L, Martin A, Saloner D, Ursell P, Robert P, Corot C, Higgins C. Discrimination of myocardial acute and chronic (scar) infarctions on delayed contrast enhanced magnetic resonance imaging with intravascular magnetic resonance contrast media. J Am Coll Cardiol. 2006 Nov 21; 48(10):1961-8. PMID: 17112985.
      View in: PubMed
    47. Woodard PK, Bluemke DA, Cascade PN, Finn JP, Stillman AE, Higgins C, White RD, Yucel EK. ACR practice guideline for the performance and interpretation of cardiac magnetic resonance imaging (MRI). J Am Coll Radiol. 2006 Sep; 3(9):665-76. PMID: 17412147.
      View in: PubMed
    48. Saeed M, Henk CB, Weber O, Martin A, Wilson M, Shunk K, Saloner D, Higgins C. Delivery and assessment of endovascular stents to repair aortic coarctation using MR and X-ray imaging. J Magn Reson Imaging. 2006 Aug; 24(2):371-8. PMID: 16786568.
      View in: PubMed
    49. Pujadas S, Reddy GP, Weber O, Tan C, Moore P, Higgins C. Phase contrast MR imaging to measure changes in collateral blood flow after stenting of recurrent aortic coarctation: initial experience. J Magn Reson Imaging. 2006 Jul; 24(1):72-6. PMID: 16755530.
      View in: PubMed
    50. Saeed M, Martin AJ, Lee RJ, Weber O, Revel D, Saloner D, Higgins C. MR guidance of targeted injections into border and core of scarred myocardium in pigs. Radiology. 2006 Aug; 240(2):419-26. PMID: 16801371.
      View in: PubMed
    51. Kramer CM, Neubauer S, Kraitchman D, Higgins C, Fogel MA, Friedrich MG, Manning WJ. Meeting highlights of the 9th annual scientific sessions of the society for cardiovascular magnetic resonance: Miami, Florida, January 20-22, 2006. J Am Coll Cardiol. 2006 Jul 04; 48(1):187-92. PMID: 16814666.
      View in: PubMed
    52. Weber OM, Higgins C. MR evaluation of cardiovascular physiology in congenital heart disease: flow and function. J Cardiovasc Magn Reson. 2006; 8(4):607-17. PMID: 16869313.
      View in: PubMed
    53. Saeed M, Lee RJ, Weber O, Do L, Martin A, Ursell P, Saloner D, Higgins C. Scarred myocardium imposes additional burden on remote viable myocardium despite a reduction in the extent of area with late contrast MR enhancement. Eur Radiol. 2006 Apr; 16(4):827-36. PMID: 16362420.
      View in: PubMed
    54. Henk CB, Higgins C, Saeed M. Endovascular interventional MRI. J Magn Reson Imaging. 2005 Oct; 22(4):451-60. PMID: 16161076.
      View in: PubMed
    55. Kramer CM, Friedrich MG, Neubauer S, Stuber M, Geva T, Higgins C, Manning WJ. Meeting highlights of the 8th Annual Scientific Sessions of the Society For Cardiovascular Magnetic Resonance, January 21 to 23, 2005. J Am Coll Cardiol. 2005 Aug 02; 46(3):411-6. PMID: 16053951.
      View in: PubMed
    56. Krombach GA, Higgins C, Chujo M, Saeed M. Gadomer-enhanced MR imaging in the detection of microvascular obstruction: alleviation with nicorandil therapy. Radiology. 2005 Aug; 236(2):510-8. PMID: 16040908.
      View in: PubMed
    57. Kuehne T, Gleason BK, Saeed M, Turner D, Weil J, Teitel DF, Higgins C, Moore P. Combined pulmonary stenosis and insufficiency preserves myocardial contractility in the developing heart of growing swine at midterm follow-up. J Appl Physiol (1985). 2005 Oct; 99(4):1422-7. PMID: 15976362.
      View in: PubMed
    58. Gotway MB, Araoz PA, Macedo TA, Stanson AW, Higgins C, Ring EJ, Dawn SK, Webb WR, Leung JW, Reddy GP. Imaging findings in Takayasu's arteritis. AJR Am J Roentgenol. 2005 Jun; 184(6):1945-50. PMID: 15908559.
      View in: PubMed
    59. Schalla S, Higgins C, Saeed M. Long-term oral treatment with nicorandil prevents the progression of left ventricular hypertrophy and preserves viability. J Cardiovasc Pharmacol. 2005 Apr; 45(4):333-40. PMID: 15772522.
      View in: PubMed
    60. Watzinger N, Lund GK, Saeed M, Reddy GP, Araoz PA, Yang M, Schwartz AB, Bedigian M, Higgins C. Myocardial blood flow in patients with dilated cardiomyopathy: quantitative assessment with velocity-encoded cine magnetic resonance imaging of the coronary sinus. J Magn Reson Imaging. 2005 Apr; 21(4):347-53. PMID: 15778950.
      View in: PubMed
    61. Schalla S, Saeed M, Higgins C, Weber O, Martin A, Moore P. Balloon sizing and transcatheter closure of acute atrial septal defects guided by magnetic resonance fluoroscopy: assessment and validation in a large animal model. J Magn Reson Imaging. 2005 Mar; 21(3):204-11. PMID: 15723375.
      View in: PubMed
    62. Kuehne T, Yilmaz S, Meinus C, Moore P, Saeed M, Weber O, Higgins C, Blank T, Elsaesser E, Schnackenburg B, Ewert P, Lange PE, Nagel E. Magnetic resonance imaging-guided transcatheter implantation of a prosthetic valve in aortic valve position: Feasibility study in swine. J Am Coll Cardiol. 2004 Dec 07; 44(11):2247-9. PMID: 15582324.
      View in: PubMed
    63. Pennell DJ, Sechtem UP, Higgins C, Manning WJ, Pohost GM, Rademakers FE, van Rossum AC, Shaw LJ, Yucel EK. Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. Eur Heart J. 2004 Nov; 25(21):1940-65. PMID: 15522474.
      View in: PubMed
    64. Kuehne T, Yilmaz S, Steendijk P, Moore P, Groenink M, Saaed M, Weber O, Higgins C, Ewert P, Fleck E, Nagel E, Schulze-Neick I, Lange P. Magnetic resonance imaging analysis of right ventricular pressure-volume loops: in vivo validation and clinical application in patients with pulmonary hypertension. Circulation. 2004 Oct 05; 110(14):2010-6. PMID: 15451801.
      View in: PubMed
    65. Viswamitra S, Higgins C, Meacham DF, Mehta JL. Magnetic resonance imaging in myocardial ischemia. Curr Opin Cardiol. 2004 Sep; 19(5):510-6. PMID: 15316461.
      View in: PubMed
    66. Weber OM, Pujadas S, Martin AJ, Higgins C. Free-breathing, three-dimensional coronary artery magnetic resonance angiography: comparison of sequences. J Magn Reson Imaging. 2004 Sep; 20(3):395-402. PMID: 15332246.
      View in: PubMed
    67. Schalla S, Higgins C, Chujo M, Saeed M. Effect of potassium-channel opener therapy on reperfused infarction in hypertrophied hearts: demonstration of preconditioning by using functional and contrast-enhanced magnetic resonance imaging. J Cardiovasc Pharmacol Ther. 2004 Sep; 9(3):193-202. PMID: 15378140.
      View in: PubMed
    68. Pujadas S, Reddy GP, Weber O, Lee JJ, Higgins C. MR imaging assessment of cardiac function. J Magn Reson Imaging. 2004 Jun; 19(6):789-99. PMID: 15170784.
      View in: PubMed
    69. Saeed M, Lee R, Martin A, Weber O, Krombach GA, Schalla S, Lee M, Saloner D, Higgins C. Transendocardial delivery of extracellular myocardial markers by using combination X-ray/MR fluoroscopic guidance: feasibility study in dogs. Radiology. 2004 Jun; 231(3):689-96. PMID: 15163809.
      View in: PubMed
    70. Lund GK, Stork A, Saeed M, Bansmann MP, Gerken JH, Müller V, Mester J, Higgins C, Adam G, Meinertz T. Acute myocardial infarction: evaluation with first-pass enhancement and delayed enhancement MR imaging compared with 201Tl SPECT imaging. Radiology. 2004 Jul; 232(1):49-57. PMID: 15166320.
      View in: PubMed
    71. Schalla S, Wendland MF, Higgins C, Ebert W, Saeed M. Accentuation of high susceptibility of hypertrophied myocardium to ischemia: complementary assessment of Gadophrin-enhancement and left ventricular function with MRI. Magn Reson Med. 2004 Mar; 51(3):552-8. PMID: 15004797.
      View in: PubMed
    72. Wang ZJ, Reddy GP, Gotway MB, Higgins C, Jablons DM, Ramaswamy M, Hawkins RA, Webb WR. Malignant pleural mesothelioma: evaluation with CT, MR imaging, and PET. Radiographics. 2004 Jan-Feb; 24(1):105-19. PMID: 14730040.
      View in: PubMed
    73. Pennell DJ, Sechtem UP, Higgins C, Manning WJ, Pohost GM, Rademakers FE, van Rossum AC, Shaw LJ, Yucel EK. Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. J Cardiovasc Magn Reson. 2004; 6(4):727-65. PMID: 15646878.
      View in: PubMed
    74. Krombach GA, Saeed M, Higgins C, Novikov V, Wendland MF. Contrast-enhanced MR delineation of stunned myocardium with administration of MnCl(2) in rats. Radiology. 2004 Jan; 230(1):183-90. PMID: 14695393.
      View in: PubMed
    75. Ansari M, Araoz PA, Gerard SK, Watzinger N, Lund GK, Massie BM, Higgins C, Saloner DA. Comparison of late enhancement cardiovascular magnetic resonance and thallium SPECT in patients with coronary disease and left ventricular dysfunction. J Cardiovasc Magn Reson. 2004; 6(2):549-56. PMID: 15137339.
      View in: PubMed
    76. Weber OM, Martin AJ, Higgins C. Whole-heart steady-state free precession coronary artery magnetic resonance angiography. Magn Reson Med. 2003 Dec; 50(6):1223-8. PMID: 14648570.
      View in: PubMed
    77. Krombach GA, Baireuther R, Higgins C, Saeed M. Distribution of intramyocardially injected extracellular MR contrast medium: effects of concentration and volume. Eur Radiol. 2004 Feb; 14(2):334-40. PMID: 14618368.
      View in: PubMed
    78. Kuehne T, Saeed M, Gleason K, Turner D, Teitel D, Higgins C, Moore P. Effects of pulmonary insufficiency on biventricular function in the developing heart of growing swine. Circulation. 2003 Oct 21; 108(16):2007-13. PMID: 14557371.
      View in: PubMed
    79. Araoz PA, Gotway MB, Trowbridge RL, Bailey RA, Auerbach AD, Reddy GP, Dawn SK, Webb WR, Higgins C. Helical CT pulmonary angiography predictors of in-hospital morbidity and mortality in patients with acute pulmonary embolism. J Thorac Imaging. 2003 Oct; 18(4):207-16. PMID: 14561905.
      View in: PubMed
    80. Reddy GP, Higgins C. Magnetic resonance imaging of congenital heart disease: evaluation of morphology and function. Semin Roentgenol. 2003 Oct; 38(4):342-51. PMID: 14621376.
      View in: PubMed
    81. Pujadas S, Reddy GP, Lee JJ, Higgins C. Magnetic resonance imaging in ischemic heart disease. Semin Roentgenol. 2003 Oct; 38(4):320-9. PMID: 14621374.
      View in: PubMed
    82. Weber OM, Schalla S, Martin AJ, Saeed M, Lee R, Shunk KA, Moore P, Higgins C. Interventional cardiac magnetic resonance imaging. Semin Roentgenol. 2003 Oct; 38(4):352-7. PMID: 14621377.
      View in: PubMed
    83. Wang ZJ, Reddy GP, Gotway MB, Yeh BM, Hetts SW, Higgins C. CT and MR imaging of pericardial disease. Radiographics. 2003 Oct; 23 Spec No:S167-80. PMID: 14557510.
      View in: PubMed
    84. Wang ZJ, Reddy GP, Gotway MB, Yeh BM, Higgins C. Cardiovascular shunts: MR imaging evaluation. Radiographics. 2003 Oct; 23 Spec No:S181-94. PMID: 14557511.
      View in: PubMed
    85. Schalla S, Saeed M, Higgins C, Martin A, Weber O, Moore P. Magnetic resonance--guided cardiac catheterization in a swine model of atrial septal defect. Circulation. 2003 Oct 14; 108(15):1865-70. PMID: 14517162.
      View in: PubMed
    86. Lund GK, Watzinger N, Saeed M, Reddy GP, Yang M, Araoz PA, Curatola D, Bedigian M, Higgins C. Chronic heart failure: global left ventricular perfusion and coronary flow reserve with velocity-encoded cine MR imaging: initial results. Radiology. 2003 Apr; 227(1):209-15. PMID: 12668746.
      View in: PubMed
    87. Kuehne T, Saeed M, Higgins C, Gleason K, Krombach GA, Weber OM, Martin AJ, Turner D, Teitel D, Moore P. Endovascular stents in pulmonary valve and artery in swine: feasibility study of MR imaging-guided deployment and postinterventional assessment. Radiology. 2003 Feb; 226(2):475-81. PMID: 12563142.
      View in: PubMed
    88. Keller RL, Aaroz PA, Hawgood S, Higgins C. MR imaging of hepatic pulmonary fusion in neonates. AJR Am J Roentgenol. 2003 Feb; 180(2):438-40. PMID: 12540449.
      View in: PubMed
    89. Araoz PA, Reddy GP, Tarnoff H, Roge CL, Higgins C. MR findings of collateral circulation are more accurate measures of hemodynamic significance than arm-leg blood pressure gradient after repair of coarctation of the aorta. J Magn Reson Imaging. 2003 Feb; 17(2):177-83. PMID: 12541224.
      View in: PubMed
    90. Bluemke DA, Krupinski EA, Ovitt T, Gear K, Unger E, Axel L, Boxt LM, Casolo G, Ferrari VA, Funaki B, Globits S, Higgins C, Julsrud P, Lipton M, Mawson J, Nygren A, Pennell DJ, Stillman A, White RD, Wichter T, Marcus F. MR Imaging of arrhythmogenic right ventricular cardiomyopathy: morphologic findings and interobserver reliability. Cardiology. 2003; 99(3):153-62. PMID: 12824723.
      View in: PubMed
    91. Watzinger N, Lund GK, Higgins C, Wendland MF, Weinmann HJ, Saeed M. The potential of contrast-enhanced magnetic resonance imaging for predicting left ventricular remodeling. J Magn Reson Imaging. 2002 Dec; 16(6):633-40. PMID: 12451576.
      View in: PubMed
    92. Krombach GA, Wendland MF, Higgins C, Saeed M. MR imaging of spatial extent of microvascular injury in reperfused ischemically injured rat myocardium: value of blood pool ultrasmall superparamagnetic particles of iron oxide. Radiology. 2002 Nov; 225(2):479-86. PMID: 12409583.
      View in: PubMed
    93. Wilson MW, LaBerge JM, Kerlan RK, Martin AJ, Weber OM, Roberts T, Vitalich C, Higgins C, Gordon RL. MR portal venography: preliminary results of fast acquisition without contrast material or breath holding. Acad Radiol. 2002 Oct; 9(10):1179-84. PMID: 12385512.
      View in: PubMed
    94. Saeed M, Watzinger N, Krombach GA, Lund GK, Wendland MF, Chujo M, Higgins C. Left ventricular remodeling after infarction: sequential MR imaging with oral nicorandil therapy in rat model. Radiology. 2002 Sep; 224(3):830-7. PMID: 12202722.
      View in: PubMed
    95. Gotway MB, Leung JW, Gooding GA, Litt HI, Reddy GP, Morita ET, Webb WR, Clark OH, Higgins C. Hyperfunctioning parathyroid tissue: spectrum of appearances on noninvasive imaging. AJR Am J Roentgenol. 2002 Aug; 179(2):495-502. PMID: 12130462.
      View in: PubMed
    96. Wendland MF, Krombach GA, Higgins C, Novikov V, Saeed M. Contrast enhanced MRI of stunned myocardium using Mn-based MRI contrast media. Acad Radiol. 2002 Aug; 9 Suppl 2:S341-2. PMID: 12188269.
      View in: PubMed
    97. Varaprasathan GA, Araoz PA, Higgins C, Reddy GP. Quantification of flow dynamics in congenital heart disease: applications of velocity-encoded cine MR imaging. Radiographics. 2002 Jul-Aug; 22(4):895-905; discussion 905-6. PMID: 12110719.
      View in: PubMed
    98. Krombach GA, Higgins C, Chujo M, Saeed M. Blood pool contrast-enhanced MRI detects suppression of microvascular permeability in early postinfarction reperfusion after nicorandil therapy. Magn Reson Med. 2002 May; 47(5):896-902. PMID: 11979568.
      View in: PubMed
    99. Kuehne T, Saeed M, Moore P, Gleason K, Reddy G, Teitel D, Higgins C. Influence of blood-pool contrast media on MR imaging and flow measurements in the presence of pulmonary arterial stents in swine. Radiology. 2002 May; 223(2):439-45. PMID: 11997550.
      View in: PubMed
    100. Wendland MF, Saeed M, Bremerich J, Arheden H, Higgins C. Thallium-like test for myocardial viability with MnDPDP-enhanced MRI. Acad Radiol. 2002 May; 9 Suppl 1:S82-3. PMID: 12019904.
      View in: PubMed
    101. Saeed M, Wendland MF, Bremerich GL, Weinmann HJ, Higgins C. Assessment of myocardial viability using standard extracellular and necrosis specific MR contrast media. Acad Radiol. 2002 May; 9 Suppl 1:S84-7. PMID: 12019905.
      View in: PubMed
    102. Watzinger N, Lund GK, Higgins C, Chujo M, Saeed M. Noninvasive assessment of the effects of nicorandil on left ventricular volumes and function in reperfused myocardial infarction. Cardiovasc Res. 2002 Apr; 54(1):77-84. PMID: 12062364.
      View in: PubMed
    103. Olsen SJ, Miller G, Breuer T, Kennedy M, Higgins C, Walford J, McKee G, Fox K, Bibb W, Mead P. A waterborne outbreak of Escherichia coli O157:H7 infections and hemolytic uremic syndrome: implications for rural water systems. Emerg Infect Dis. 2002 Apr; 8(4):370-5. PMID: 11971769; PMCID: PMC2730238.
    104. Araoz PA, Reddy GP, Thomson PD, Higgins C. Images in cardiovascular medicine. Magnetic resonance angiography of criss-cross heart. Circulation. 2002 Jan 29; 105(4):537-8. PMID: 11815440.
      View in: PubMed
    105. Schalla S, Higgins C, Saeed M. Contrast agents for cardiovascular magnetic resonance imaging. Current status and future directions. Drugs R D. 2002; 3(5):285-302. PMID: 12455148.
      View in: PubMed