Daniele Canzio, PhD
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Title(s) | Assistant Professor, Neurology |
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School | School of Medicine |
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Address | 555 Mission Bay Blvd South San Francisco CA 94158
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Phone | 415-514-2240 |
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vCard | Download vCard |
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Title(s) | UCSF Weill Institute for Neurosciences |
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Biography Columbia University , New York | | 12/2018 | Molecular Biology/Neuroscience | University of California, San Francisco, San Francisco | PhD | 12/2012 | Chemical Biology | University of California, Santa Barbara, Santa Barbara | BS | 03/2006 | Chemistry/Biochemistry |
Columbia University | 2014
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| 2017 | Helen Hay Whitney Postdoctoral Research Fellowship |
Overview My laboratory is interested in understanding the molecular mechanism regulating the generation of cell-surface neural identities by Clustered Protocadherin genes. This process is of fundamental importance to the assembly of neural circuits in the mammalian brain.
Research ORNG Applications Bibliographic
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
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The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice. Neuron. 2020 06 03; 106(5):789-805.e5.
Gerbino V, Kaunga E, Ye J, Canzio D, O'Keeffe S, Rudnick ND, Guarnieri P, Lutz CM, Maniatis T. PMID: 32220666.
View in: PubMed Mentions: 5 Fields: Translation: AnimalsCells
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The generation of a protocadherin cell-surface recognition code for neural circuit assembly. Curr Opin Neurobiol. 2019 12; 59:213-220.
Canzio D, Maniatis T. PMID: 31710891.
View in: PubMed Mentions: 4 Fields: Translation: Cells
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Clustered protocadherins methylation alterations in cancer. Clin Epigenetics. 2019 07 09; 11(1):100.
Vega-Benedetti AF, Loi E, Moi L, Blois S, Fadda A, Antonelli M, Arcella A, Badiali M, Giangaspero F, Morra I, Columbano A, Restivo A, Zorcolo L, Gismondi V, Varesco L, Bellomo SE, Giordano S, Canale M, Casadei-Gardini A, Faloppi L, Puzzoni M, Scartozzi M, Ziranu P, Cabras G, Cocco P, Ennas MG, Satta G, Zucca M, Canzio D, Zavattari P. PMID: 31288858.
View in: PubMed Mentions: 4 Fields: Translation: HumansCells
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Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin a Promoter Choice. Cell. 2019 04 18; 177(3):639-653.e15.
Canzio D, Nwakeze CL, Horta A, Rajkumar SM, Coffey EL, Duffy EE, Duffié R, Monahan K, O'Keeffe S, Simon MD, Lomvardas S, Maniatis T. PMID: 30955885.
View in: PubMed Mentions: 22 Fields: Translation: HumansAnimalsCells
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Writing, Reading, and Translating the Clustered Protocadherin Cell Surface Recognition Code for Neural Circuit Assembly. Annu Rev Cell Dev Biol. 2018 10 06; 34:471-493.
Mountoufaris G, Canzio D, Nwakeze CL, Chen WV, Maniatis T. PMID: 30296392.
View in: PubMed Mentions: 17 Fields: Translation: HumansAnimalsCells
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Solid phase chemistry to covalently and reversibly capture thiolated RNA. Nucleic Acids Res. 2018 08 21; 46(14):6996-7005.
Duffy EE, Canzio D, Maniatis T, Simon MD. PMID: 29986098.
View in: PubMed Mentions: 1 Fields: Translation: HumansAnimalsCells
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CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell. 2015 Aug 13; 162(4):900-10.
Guo Y, Xu Q, Canzio D, Shou J, Li J, Gorkin DU, Jung I, Wu H, Zhai Y, Tang Y, Lu Y, Wu Y, Jia Z, Li W, Zhang MQ, Ren B, Krainer AR, Maniatis T, Wu Q. PMID: 26276636.
View in: PubMed Mentions: 236 Fields: Translation: HumansAnimalsCells
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Mechanisms of functional promiscuity by HP1 proteins. Trends Cell Biol. 2014 Jun; 24(6):377-86.
Canzio D, Larson A, Narlikar GJ. PMID: 24618358.
View in: PubMed Mentions: 56 Fields: Translation: HumansAnimalsCells
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A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature. 2013 Apr 18; 496(7445):377-81.
Canzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Marina DB, Garcia JF, Madhani HD, Cooke R, Schuck P, Cheng Y, Narlikar GJ. PMID: 23485968.
View in: PubMed Mentions: 46 Fields: Translation: AnimalsCells
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Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution. Science. 2011 Nov 18; 334(6058):977-82.
Armache KJ, Garlick JD, Canzio D, Narlikar GJ, Kingston RE. PMID: 22096199.
View in: PubMed Mentions: 114 Fields: Translation: AnimalsCells
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Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Mol Cell. 2011 Jan 07; 41(1):67-81.
Canzio D, Chang EY, Shankar S, Kuchenbecker KM, Simon MD, Madhani HD, Narlikar GJ, Al-Sady B. PMID: 21211724.
View in: PubMed Mentions: 107 Fields: Translation: Cells
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Incorporation of positively charged ribonucleic guanidine linkages into oligodeoxyribonucleotides: Development of potent antisense agents. Bioorg Med Chem Lett. 2008 Apr 01; 18(7):2377-84.
Park M, Canzio D, Bruice TC. PMID: 18353646.
View in: PubMed Mentions: 1 Fields: Translation: Cells
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DNA sequence recognition by Hoechst 33258 conjugates of hairpin pyrrole/imidazole polyamides. Bioorg Med Chem Lett. 2006 Jul 15; 16(14):3745-50.
Correa BJ, Canzio D, Kahane AL, Reddy PM, Bruice TC. PMID: 16682192.
View in: PubMed Mentions: 2 Fields: Translation: Cells
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Year | Publications |
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2006 | 1 | 2008 | 1 | 2011 | 2 | 2013 | 1 | 2014 | 1 | 2015 | 1 | 2018 | 2 | 2019 | 3 | 2020 | 1 |
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