Nariman Naber • UCSF Profiles

Nariman Naber, PhD

Title(s)	Research Biochemist, Biochemistry and Biophysics
School	School of Medicine
Address	600 16th St, #S416 San Francisco CA 94158
Phone	415-476-1975
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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The role of the super-relaxed state of myosin in human metabolism. Metabol Open. 2021 Mar; 9:100068. Wilson C, Naber N, Cooke R. PMID: 33364594; PMCID: PMC7753139.

View in: PubMed Mentions: 5
Piperine, an alkaloid inhibiting the super-relaxed state of myosin, binds to the myosin regulatory light chain. Arch Biochem Biophys. 2018 12 01; 659:75-84. Tolkatchev D, Elnatan D, Nogara L, Ly T, Naber N, Haak K, Meech R, Cooke R, Kostyukova AS. PMID: 30287237; PMCID: PMC6699511.

View in: PubMed Mentions: 5 Fields:
Bio Biochemistry Bio Biophysics
Translation:Animals Cells
Piperine's mitigation of obesity and diabetes can be explained by its up-regulation of the metabolic rate of resting muscle. Proc Natl Acad Sci U S A. 2016 11 15; 113(46):13009-13014. Nogara L, Naber N, Pate E, Canton M, Reggiani C, Cooke R. PMID: 27799519; PMCID: PMC5135373.

View in: PubMed Mentions: 17 Fields:
Sci Science
Translation:Animals Cells
Spectroscopic Studies of the Super Relaxed State of Skeletal Muscle. PLoS One. 2016; 11(8):e0160100. Nogara L, Naber N, Pate E, Canton M, Reggiani C, Cooke R. PMID: 27479128; PMCID: PMC4968846.

View in: PubMed Mentions: 19 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
A novel N-terminal extension in mitochondrial TRAP1 serves as a thermal regulator of chaperone activity. Elife. 2014 Dec 22; 3. Partridge JR, Lavery LA, Elnatan D, Naber N, Cooke R, Agard DA. PMID: 25531069; PMCID: PMC4381864.

View in: PubMed Mentions: 22 Fields:
Bio Biology
Translation:Humans Cells
The myosin inhibitor blebbistatin stabilizes the super-relaxed state in skeletal muscle. Biophys J. 2014 Oct 07; 107(7):1637-46. Wilson C, Naber N, Pate E, Cooke R. PMID: 25296316; PMCID: PMC4190596.

View in: PubMed Mentions: 48 Fields:
Bio Biophysics
Translation:Animals Cells
The histone H4 tail regulates the conformation of the ATP-binding pocket in the SNF2h chromatin remodeling enzyme. J Mol Biol. 2014 May 15; 426(10):2034-44. Racki LR, Naber N, Pate E, Leonard JD, Cooke R, Narlikar GJ. PMID: 24607692; PMCID: PMC4059342.

View in: PubMed Mentions: 18 Fields:
Mol Molecular Biology
Translation:Humans Animals Cells
A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature. 2013 Apr 18; 496(7445):377-81. Canzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Marina DB, Garcia JF, Madhani HD, Cooke R, Schuck P, Cheng Y, Narlikar GJ. PMID: 23485968; PMCID: PMC3907283.

View in: PubMed Mentions: 82 Fields:
Sci Science
Translation:Animals Cells
Conformational changes at the nucleotide site in the presence of bound ADP do not set the velocity of fast Drosophila myosins. J Muscle Res Cell Motil. 2013 Feb; 34(1):35-42. Eldred CC, Naber N, Pate E, Cooke R, Swank DM. PMID: 23203294; PMCID: PMC3552063.

View in: PubMed Mentions: 3 Fields:
Cel Cell Biology Phy Physiology
Translation:Animals Cells
The loop 5 element structurally and kinetically coordinates dimers of the human kinesin-5, Eg5. Biophys J. 2011 Dec 07; 101(11):2760-9. Waitzman JS, Larson AG, Cochran JC, Naber N, Cooke R, Jon Kull F, Pate E, Rice SE. PMID: 22261065; PMCID: PMC3297777.

View in: PubMed Mentions: 20 Fields:
Bio Biophysics
Translation:Humans Cells
Analysis of the interaction of the Eg5 Loop5 with the nucleotide site. J Theor Biol. 2011 Nov 21; 289:107-15. Harrington TD, Naber N, Larson AG, Cooke R, Rice SE, Pate E. PMID: 21872609; PMCID: PMC3191284.

View in: PubMed Mentions: 4 Fields:
Bio Biology
Translation:Humans Cells
Slow myosin ATP turnover in the super-relaxed state in tarantula muscle. J Mol Biol. 2011 Sep 02; 411(5):943-50. Naber N, Cooke R, Pate E. PMID: 21763701; PMCID: PMC3156359.

View in: PubMed Mentions: 49 Fields:
Mol Molecular Biology
Translation:Animals Cells
EPR spectra and molecular dynamics agree that the nucleotide pocket of myosin V is closed and that it opens on binding actin. J Mol Biol. 2011 Aug 05; 411(1):16-26. Purcell TJ, Naber N, Sutton S, Cooke R, Pate E. PMID: 21640122; PMCID: PMC3143297.

View in: PubMed Mentions: 1 Fields:
Mol Molecular Biology
Translation:Animals Cells
Multiple conformations of the nucleotide site of Kinesin family motors in the triphosphate state. J Mol Biol. 2011 May 13; 408(4):628-42. Naber N, Larson A, Rice S, Cooke R, Pate E. PMID: 21277856; PMCID: PMC4262519.

View in: PubMed Mentions: 4 Fields:
Mol Molecular Biology
Translation:Humans Animals Cells
Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency. J Mol Biol. 2011 Mar 18; 407(1):79-91. Purcell TJ, Naber N, Franks-Skiba K, Dunn AR, Eldred CC, Berger CL, Málnási-Csizmadia A, Spudich JA, Swank DM, Pate E, Cooke R. PMID: 21185304; PMCID: PMC3347976.

View in: PubMed Mentions: 11 Fields:
Mol Molecular Biology
Translation:Animals Cells
The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5. Biophys J. 2010 Jun 02; 98(11):2619-27. Larson AG, Naber N, Cooke R, Pate E, Rice SE. PMID: 20513406; PMCID: PMC2877332.

View in: PubMed Mentions: 24 Fields:
Bio Biophysics
Translation:Cells
Combining EPR with fluorescence spectroscopy to monitor conformational changes at the myosin nucleotide pocket. J Mol Biol. 2010 Mar 05; 396(4):937-48. Naber N, Málnási-Csizmadia A, Purcell TJ, Cooke R, Pate E. PMID: 20036250.

View in: PubMed Mentions: 9 Fields:
Mol Molecular Biology
Translation:Animals Cells
The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes. Nature. 2009 Dec 24; 462(7276):1016-21. Racki LR, Yang JG, Naber N, Partensky PD, Acevedo A, Purcell TJ, Cooke R, Cheng Y, Narlikar GJ. PMID: 20033039; PMCID: PMC2869534.

View in: PubMed Mentions: 100 Fields:
Sci Science
Translation:Humans Animals Cells
The fate of free radicals in a cellulose based hydrogel: detection by electron paramagnetic resonance spectroscopy. J Pharm Sci. 2009 Jul; 98(7):2464-71. Basumallick L, Ji JA, Naber N, Wang YJ. PMID: 19090570.

View in: PubMed Mentions: 3 Fields:
Pha Pharmacology
The Kinesin-1 tail conformationally restricts the nucleotide pocket. Biophys J. 2009 Apr 08; 96(7):2799-807. Wong YL, Dietrich KA, Naber N, Cooke R, Rice SE. PMID: 19348763; PMCID: PMC2711265.

View in: PubMed Mentions: 17 Fields:
Bio Biophysics
Translation:Humans Cells
Structural dynamics of the actomyosin complex probed by a bifunctional spin label that cross-links SH1 and SH2. Biophys J. 2008 Dec; 95(11):5238-46. Thompson AR, Naber N, Wilson C, Cooke R, Thomas DD. PMID: 18805936; PMCID: PMC2586570.

View in: PubMed Mentions: 14 Fields:
Bio Biophysics
Translation:Animals Cells
Dynamics of the nucleotide pocket of myosin measured by spin-labeled nucleotides. Biophys J. 2007 Jan 01; 92(1):172-84. Naber N, Purcell TJ, Pate E, Cooke R. PMID: 17028139; PMCID: PMC1697850.

View in: PubMed Mentions: 17 Fields:
Bio Biophysics
Translation:Animals Cells
Conformational variations in an infectious protein determine prion strain differences. Nature. 2004 Mar 18; 428(6980):323-8. Tanaka M, Chien P, Naber N, Cooke R, Weissman JS. PMID: 15029196.

View in: PubMed Mentions: 397 Fields:
Sci Science
Translation:Animals Cells
Closing of the nucleotide pocket of kinesin-family motors upon binding to microtubules. Science. 2003 May 02; 300(5620):798-801. Naber N, Minehardt TJ, Rice S, Chen X, Grammer J, Matuska M, Vale RD, Kollman PA, Car R, Yount RG, Cooke R, Pate E. PMID: 12730601.

View in: PubMed Mentions: 26 Fields:
Sci Science
Translation:Humans Animals Cells
EPR spectroscopy shows a microtubule-dependent conformational change in the kinesin switch 1 domain. Biophys J. 2003 May; 84(5):3190-6. Naber N, Rice S, Matuska M, Vale RD, Cooke R, Pate E. PMID: 12719248; PMCID: PMC1302879.

View in: PubMed Mentions: 17 Fields:
Bio Biophysics
Translation:Cells