Yifan Cheng, PhD

Title(s)Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th St, #S474
San Francisco CA 94158
Phone415-514-9708
ORCID ORCID Icon0000-0001-9535-0369 Additional info
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    Collapse Overview 
    Collapse Overview
    We are interested in studying the three-dimensional structures of macromolecular complexes: their structural architectures, the regulation of their function and the dynamic processes of their assembly and disassembly, by molecular electron microscopy (cryoEM). A full understanding of the biological functions/processes of any macromolecular complex requires structural information at a wide range of resolutions, including atomic details of its components, spatial arrangements of these components and interactions between them. CryoEM can be used to study macromolecules in their native conformations at a wide resolution range, from sub-nanometer resolution (single particle cryoEM) to the cellular level (electron tomography).

    Collapse Research 
    Collapse Research Activities and Funding
    Advancing cryo-EM technology to address difficult biological questions
    NIH R35GM140847Apr 1, 2021 - Feb 28, 2026
    Role: Principal Investigator
    Structural mechanism of integrin-mediated TGF-b activation
    NIH R01HL134183Jul 4, 2016 - May 31, 2024
    Role: Co-Principal Investigator
    Acquisition of an electron microscope for high-resolution single particle cryo-EM
    NIH S10OD021741May 1, 2016 - Apr 30, 2017
    Role: Principal Investigator
    Mapping the conformational cycle of transmembrane transporters
    NIH P01GM111126Aug 1, 2015 - Jul 31, 2020
    Role: Co-Investigator
    Linux cluster for near atomic resolution single particle cryo-EM
    NIH S10OD020054Apr 15, 2015 - Apr 14, 2016
    Role: Principal Investigator
    Structures and gating mechanisms of TRP ion channels
    NIH R01GM098672Aug 1, 2011 - Jun 30, 2020
    Role: Principal Investigator
    GPU Computing Enabled Linux Computer Cluster
    NIH S10RR026814Jan 28, 2010 - Jan 27, 2012
    Role: Principal Investigator
    Mechanism of gate-opening in the 20S proteasome induced by the proteasomal ATPase
    NIH R01GM082893Jan 1, 2008 - Mar 31, 2019
    Role: Principal Investigator
    HARC Center: HIV Accessory and Regulatory Complexes
    NIH P50GM082250Aug 27, 2007 - Aug 31, 2022
    Role: Co-Investigator
    National Resource for Automated Molecular Microscopy
    NIH P41RR017573Sep 30, 2002 - Jul 31, 2012
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA. Elife. 2014 Dec 08; 3:e04121. Booth DS, Cheng Y, Frankel AD. PMID: 25486595; PMCID: PMC4360530.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    2. Allosteric communication in the dynein motor domain. Cell. 2014 Nov 06; 159(4):857-68. Bhabha G, Cheng HC, Zhang N, Moeller A, Liao M, Speir JA, Cheng Y, Vale RD. PMID: 25417161; PMCID: PMC4269335.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    3. Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter. Nature. 2015 Jan 15; 517(7534):396-400. Kim J, Wu S, Tomasiak TM, Mergel C, Winter MB, Stiller SB, Robles-Colmanares Y, Stroud RM, Tampé R, Craik CS, Cheng Y. PMID: 25363761; PMCID: PMC4372080.
      View in: PubMed   Mentions: 63     Fields:    Translation:Cells
    4. Localization events-based sample drift correction for localization microscopy with redundant cross-correlation algorithm. Opt Express. 2014 Jun 30; 22(13):15982-91. Wang Y, Schnitzbauer J, Hu Z, Li X, Cheng Y, Huang ZL, Huang B. PMID: 24977854; PMCID: PMC4162368.
      View in: PubMed   Mentions: 66     Fields:    Translation:Animals
    5. Selective targeting of TGF-β activation to treat fibroinflammatory airway disease. Sci Transl Med. 2014 Jun 18; 6(241):241ra79. Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL. PMID: 24944194; PMCID: PMC4341974.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    6. Single particle electron cryo-microscopy of a mammalian ion channel. Curr Opin Struct Biol. 2014 Aug; 27:1-7. Liao M, Cao E, Julius D, Cheng Y. PMID: 24681231; PMCID: PMC4176607.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    7. Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis. Proc Natl Acad Sci U S A. 2014 Apr 08; 111(14):5189-94. Lu J, Yu Y, Zhu I, Cheng Y, Sun PD. PMID: 24706838; PMCID: PMC3986191.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    8. CTER-rapid estimation of CTF parameters with error assessment. Ultramicroscopy. 2014 May; 140:9-19. Penczek PA, Fang J, Li X, Cheng Y, Loerke J, Spahn CM. PMID: 24562077; PMCID: PMC4016771.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    9. Structure of the TRPV1 ion channel determined by electron cryo-microscopy. Nature. 2013 Dec 05; 504(7478):107-12. Liao M, Cao E, Julius D, Cheng Y. PMID: 24305160; PMCID: PMC4078027.
      View in: PubMed   Mentions: 792     Fields:    Translation:HumansAnimalsCells
    10. TRPV1 structures in distinct conformations reveal activation mechanisms. Nature. 2013 Dec 05; 504(7478):113-8. Cao E, Liao M, Cheng Y, Julius D. PMID: 24305161; PMCID: PMC4023639.
      View in: PubMed   Mentions: 514     Fields:    Translation:AnimalsCells
    11. Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. Dev Cell. 2013 Nov 25; 27(4):425-37. Asensio CS, Sirkis DW, Maas JW, Egami K, To TL, Brodsky FM, Shu X, Cheng Y, Edwards RH. PMID: 24210660; PMCID: PMC3974617.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    12. Influence of electron dose rate on electron counting images recorded with the K2 camera. J Struct Biol. 2013 Nov; 184(2):251-60. Li X, Zheng SQ, Egami K, Agard DA, Cheng Y. PMID: 23968652; PMCID: PMC3854003.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    13. Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis. Cell. 2013 May 23; 153(5):1012-24. Qian MX, Pang Y, Liu CH, Haratake K, Du BY, Ji DY, Wang GF, Zhu QQ, Song W, Yu Y, Zhang XX, Huang HT, Miao S, Chen LB, Zhang ZH, Liang YN, Liu S, Cha H, Yang D, Zhai Y, Komatsu T, Tsuruta F, Li H, Cao C, Li W, Li GH, Cheng Y, Chiba T, Wang L, Goldberg AL, Shen Y, Qiu XB. PMID: 23706739; PMCID: PMC3983474.
      View in: PubMed   Mentions: 160     Fields:    Translation:HumansAnimalsCells
    14. Reconfiguration of the proteasome during chaperone-mediated assembly. Nature. 2013 May 23; 497(7450):512-6. Park S, Li X, Kim HM, Singh CR, Tian G, Hoyt MA, Lovell S, Battaile KP, Zolkiewski M, Coffino P, Roelofs J, Cheng Y, Finley D. PMID: 23644457; PMCID: PMC3687086.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    15. Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM. Nat Methods. 2013 Jun; 10(6):584-90. Li X, Mooney P, Zheng S, Booth CR, Braunfeld MB, Gubbens S, Agard DA, Cheng Y. PMID: 23644547; PMCID: PMC3684049.
      View in: PubMed   Mentions: 990     Fields:    Translation:Cells
    16. A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature. 2013 Apr 18; 496(7445):377-81. Canzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Marina DB, Garcia JF, Madhani HD, Cooke R, Schuck P, Cheng Y, Narlikar GJ. PMID: 23485968; PMCID: PMC3907283.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    17. Recording high-resolution images of two-dimensional crystals of membrane proteins. Methods Mol Biol. 2013; 955:129-52. Avila-Sakar A, Li X, Zheng SQ, Cheng Y. PMID: 23132059.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. A method for integrative structure determination of protein-protein complexes. Bioinformatics. 2012 Dec 15; 28(24):3282-9. Schneidman-Duhovny D, Rossi A, Avila-Sakar A, Kim SJ, Velázquez-Muriel J, Strop P, Liang H, Krukenberg KA, Liao M, Kim HM, Sobhanifar S, Dötsch V, Rajpal A, Pons J, Agard DA, Cheng Y, Sali A. PMID: 23093611; PMCID: PMC3519461.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    19. Self-assembly of filamentous amelogenin requires calcium and phosphate: from dimers via nanoribbons to fibrils. Biomacromolecules. 2012 Nov 12; 13(11):3494-502. Martinez-Avila O, Wu S, Kim SJ, Cheng Y, Khan F, Samudrala R, Sali A, Horst JA, Habelitz S. PMID: 22974364; PMCID: PMC3496023.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    20. Fabs enable single particle cryoEM studies of small proteins. Structure. 2012 Apr 04; 20(4):582-92. Wu S, Avila-Sakar A, Kim J, Booth DS, Greenberg CH, Rossi A, Liao M, Li X, Alian A, Griner SL, Juge N, Yu Y, Mergel CM, Chaparro-Riggers J, Strop P, Tampé R, Edwards RH, Stroud RM, Craik CS, Cheng Y. PMID: 22483106; PMCID: PMC3322386.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    21. Visualizing proteins and macromolecular complexes by negative stain EM: from grid preparation to image acquisition. J Vis Exp. 2011 Dec 22; (58). Booth DS, Avila-Sakar A, Cheng Y. PMID: 22215030; PMCID: PMC3369646.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    22. Self-assembly of amelogenin proteins at the water-oil interface. Eur J Oral Sci. 2011 Dec; 119 Suppl 1:75-82. Martinez-Avila OM, Wu S, Cheng Y, Lee R, Khan F, Habelitz S. PMID: 22243231; PMCID: PMC6339812.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    23. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem. 2011 Jun 10; 286(23):20710-26. Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. PMID: 21489994; PMCID: PMC3121472.
      View in: PubMed   Mentions: 300     Fields:    Translation:HumansAnimalsCells
    24. A distributed multi-GPU system for high speed electron microscopic tomographic reconstruction. Ultramicroscopy. 2011 Jul; 111(8):1137-43. Zheng SQ, Branlund E, Kesthelyi B, Braunfeld MB, Cheng Y, Sedat JW, Agard DA. PMID: 21741915; PMCID: PMC3190582.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    25. Self-aligning amelogenin nanoribbons in oil-water system. J Struct Biol. 2011 Apr; 174(1):203-12. He X, Wu S, Martinez-Avila O, Cheng Y, Habelitz S. PMID: 21134461; PMCID: PMC3204882.
      View in: PubMed   Mentions: 20     Fields:    
    26. Structure characterization of the 26S proteasome. Biochim Biophys Acta. 2011 Feb; 1809(2):67-79. Kim HM, Yu Y, Cheng Y. PMID: 20800708; PMCID: PMC3010250.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    27. HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes. Proc Natl Acad Sci U S A. 2010 Jul 13; 107(28):12481-6. Daugherty MD, Booth DS, Jayaraman B, Cheng Y, Frankel AD. PMID: 20616058; PMCID: PMC2906596.
      View in: PubMed   Mentions: 55     Fields:    Translation:Cells
    28. GPU-enabled FREALIGN: accelerating single particle 3D reconstruction and refinement in Fourier space on graphics processors. J Struct Biol. 2010 Dec; 172(3):407-12. Li X, Grigorieff N, Cheng Y. PMID: 20558298; PMCID: PMC2964447.
      View in: PubMed   Mentions: 22     Fields:    
    29. Collecting electron crystallographic data of two-dimensional protein crystals. Methods Enzymol. 2010; 481:251-82. Hite RK, Schenk AD, Li Z, Cheng Y, Walz T. PMID: 20887861.
      View in: PubMed   Mentions: 5     Fields:    
    30. HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Traffic. 2010 Jan; 11(1):110-22. Lenassi M, Cagney G, Liao M, Vaupotic T, Bartholomeeusen K, Cheng Y, Krogan NJ, Plemenitas A, Peterlin BM. PMID: 19912576; PMCID: PMC2796297.
      View in: PubMed   Mentions: 304     Fields:    Translation:HumansCells
    31. The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes. Nature. 2009 Dec 24; 462(7276):1016-21. Racki LR, Yang JG, Naber N, Partensky PD, Acevedo A, Purcell TJ, Cooke R, Cheng Y, Narlikar GJ. PMID: 20033039; PMCID: PMC2869534.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    32. Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. EMBO J. 2010 Feb 03; 29(3):692-702. Yu Y, Smith DM, Kim HM, Rodriguez V, Goldberg AL, Cheng Y. PMID: 20019667; PMCID: PMC2830694.
      View in: PubMed   Mentions: 70     Fields:    Translation:Cells
    33. Evaluation of imaging plates as recording medium for images of negatively stained single particles and electron diffraction patterns of two-dimensional crystals. J Electron Microsc (Tokyo). 2010; 59(1):53-63. Li Z, Hite RK, Cheng Y, Walz T. PMID: 19643814; PMCID: PMC3156676.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    34. Toward an atomic model of the 26S proteasome. Curr Opin Struct Biol. 2009 Apr; 19(2):203-8. Cheng Y. PMID: 19286367; PMCID: PMC2743420.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    35. A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis. Biochim Biophys Acta. 2009 May; 1793(5):772-80. Kim HZ, Jung K, Kim HM, Cheng Y, Koh GY. PMID: 19339208.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    36. The advent of near-atomic resolution in single-particle electron microscopy. Annu Rev Biochem. 2009; 78:723-42. Cheng Y, Walz T. PMID: 19489732.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    37. Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases. Mol Cell. 2008 May 09; 30(3):360-8. Rabl J, Smith DM, Yu Y, Chang SC, Goldberg AL, Cheng Y. PMID: 18471981; PMCID: PMC4141531.
      View in: PubMed   Mentions: 215     Fields:    Translation:AnimalsCells
    38. A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3739-44. Frey G, Peng H, Rits-Volloch S, Morelli M, Cheng Y, Chen B. PMID: 18322015; PMCID: PMC2268799.
      View in: PubMed   Mentions: 160     Fields:    Translation:Cells
    39. In vitro self-assembly of tailorable nanotubes from a simple protein building block. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3733-8. Ballister ER, Lai AH, Zuckermann RN, Cheng Y, Mougous JD. PMID: 18310321; PMCID: PMC2268831.
      View in: PubMed   Mentions: 111     Fields:    Translation:Cells
    40. Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1. Mol Cell. 2007 Dec 14; 28(5):871-85. Ohi MD, Feoktistova A, Ren L, Yip C, Cheng Y, Chen JS, Yoon HJ, Wall JS, Huang Z, Penczek PA, Gould KL, Walz T. PMID: 18082611; PMCID: PMC2197158.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    41. Polymorphic assemblies and crystalline arrays of lens tetraspanin MP20. J Mol Biol. 2008 Feb 15; 376(2):380-92. Gonen T, Hite RK, Cheng Y, Petre BM, Kistler J, Walz T. PMID: 18166196.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    42. Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry. Mol Cell. 2007 Sep 07; 27(5):731-44. Smith DM, Chang SC, Park S, Finley D, Cheng Y, Goldberg AL. PMID: 17803938; PMCID: PMC2083707.
      View in: PubMed   Mentions: 283     Fields:    Translation:AnimalsCells
    43. Reconstructing the endocytotic machinery. Methods Cell Biol. 2007; 79:463-87. Cheng Y, Walz T. PMID: 17327169.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    44. Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. J Mol Biol. 2007 Jan 19; 365(3):892-9. Cheng Y, Boll W, Kirchhausen T, Harrison SC, Walz T. PMID: 17095010; PMCID: PMC1839968.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    45. Activation of leukocyte beta2 integrins by conversion from bent to extended conformations. Immunity. 2006 Oct; 25(4):583-94. Nishida N, Xie C, Shimaoka M, Cheng Y, Walz T, Springer TA. PMID: 17045822.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansCells
    46. Electron tomography of swollen rigor fibers of insect flight muscle reveals a short and variably angled S2 domain. J Mol Biol. 2006 Sep 29; 362(4):844-60. Liu J, Wu S, Reedy MC, Winkler H, Lucaveche C, Cheng Y, Reedy MK, Taylor KA. PMID: 16949613.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    47. Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy. J Struct Biol. 2006 Dec; 156(3):453-60. Fotin A, Kirchhausen T, Grigorieff N, Harrison SC, Walz T, Cheng Y. PMID: 16908193; PMCID: PMC2910098.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    48. Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins. Biol Chem. 2006 Feb; 387(2):179-87. Nakagawa T, Cheng Y, Sheng M, Walz T. PMID: 16497150.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    49. ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins. Mol Cell. 2005 Dec 09; 20(5):687-98. Smith DM, Kafri G, Cheng Y, Ng D, Walz T, Goldberg AL. PMID: 16337593.
      View in: PubMed   Mentions: 140     Fields:    Translation:AnimalsCells
    50. Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature. 2005 Dec 01; 438(7068):633-8. Gonen T, Cheng Y, Sliz P, Hiroaki Y, Fujiyoshi Y, Harrison SC, Walz T. PMID: 16319884; PMCID: PMC1350984.
      View in: PubMed   Mentions: 303     Fields:    Translation:AnimalsCells
    51. Single particle reconstruction of the human apo-transferrin-transferrin receptor complex. J Struct Biol. 2005 Dec; 152(3):204-10. Cheng Y, Zak O, Aisen P, Harrison SC, Walz T. PMID: 16343946.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    52. Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques. J Mol Biol. 2006 Feb 03; 355(5):1048-65. Cheng Y, Wolf E, Larvie M, Zak O, Aisen P, Grigorieff N, Harrison SC, Walz T. PMID: 16343539.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    53. Structure and different conformational states of native AMPA receptor complexes. Nature. 2005 Feb 03; 433(7025):545-9. Nakagawa T, Cheng Y, Ramm E, Sheng M, Walz T. PMID: 15690046.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    54. Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature. 2004 Dec 02; 432(7017):573-9. Fotin A, Cheng Y, Sliz P, Grigorieff N, Harrison SC, Kirchhausen T, Walz T. PMID: 15502812.
      View in: PubMed   Mentions: 214     Fields:    Translation:AnimalsCells
    55. Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature. 2004 Dec 02; 432(7017):649-53. Fotin A, Cheng Y, Grigorieff N, Walz T, Harrison SC, Kirchhausen T. PMID: 15502813.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    56. Aquaporin-0 membrane junctions form upon proteolytic cleavage. J Mol Biol. 2004 Sep 24; 342(4):1337-45. Gonen T, Cheng Y, Kistler J, Walz T. PMID: 15351655.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    57. Aquaporin-0 membrane junctions reveal the structure of a closed water pore. Nature. 2004 May 13; 429(6988):193-7. Gonen T, Sliz P, Kistler J, Cheng Y, Walz T. PMID: 15141214.
      View in: PubMed   Mentions: 154     Fields:    Translation:AnimalsCells
    58. A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase. J Virol. 2004 May; 78(9):4508-16. Chen B, Cheng Y, Calder L, Harrison SC, Reinherz EL, Skehel JJ, Wiley DC. PMID: 15078931; PMCID: PMC387710.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    59. Negative Staining and Image Classification - Powerful Tools in Modern Electron Microscopy. Biol Proced Online. 2004; 6:23-34. Ohi M, Li Y, Cheng Y, Walz T. PMID: 15103397; PMCID: PMC389902.
      View in: PubMed   Mentions: 386  
    60. Structure of the human transferrin receptor-transferrin complex. Cell. 2004 Feb 20; 116(4):565-76. Cheng Y, Zak O, Aisen P, Harrison SC, Walz T. PMID: 14980223.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansAnimalsCells
    61. The crystal structure of the bifunctional primase-helicase of bacteriophage T7. Mol Cell. 2003 Nov; 12(5):1113-23. Toth EA, Li Y, Sawaya MR, Cheng Y, Ellenberger T. PMID: 14636571.
      View in: PubMed   Mentions: 76     Fields:    Translation:Cells
    62. Structure of the Sec23p/24p and Sec13p/31p complexes of COPII. Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19):10704-9. Lederkremer GZ, Cheng Y, Petre BM, Vogan E, Springer S, Schekman R, Walz T, Kirchhausen T. PMID: 11535824; PMCID: PMC58530.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    63. The three-dimensional map of microsomal glutathione transferase 1 at 6 A resolution. EMBO J. 2000 Dec 01; 19(23):6311-6. Schmidt-Krey I, Mitsuoka K, Hirai T, Murata K, Cheng Y, Fujiyoshi Y, Morgenstern R, Hebert H. PMID: 11101503; PMCID: PMC305867.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    64. The projection structure of the membrane protein microsomal glutathione transferase at 3 A resolution as determined from two-dimensional hexagonal crystals. J Mol Biol. 1999 Apr 30; 288(2):243-53. Schmidt-Krey I, Murata K, Hirai T, Mitsuoka K, Cheng Y, Morgenstern R, Fujiyoshi Y, Hebert H. PMID: 10329140.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    65. Influence of various nucleotides on the in situ crystallization of Ca2+-ATPase. Biochim Biophys Acta. 1999 Jan 08; 1415(2):361-8. Hiroaki Y, Mitsuoka K, Cheng Y, Hiroaki H, Fujiyoshi Y. PMID: 9889398.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    66. Characterization of the low magnification performance of a Philips CM300-FEG. Ultramicroscopy. 1998 Sep; 74(4):209-20. Cheng Y, Taylor KA. PMID: 9809458.
      View in: PubMed   Mentions:    Fields:    
    67. The use of electron tomography for structural analysis of disordered protein arrays. J Struct Biol. 1997 Dec; 120(3):372-86. Taylor KA, Tang J, Cheng Y, Winkler H. PMID: 9441940.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
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