Eric Figueroa, PhD

Title(s)Postdoctoral Scholar, Physiology
SchoolSchool of Medicine
Address600 16th Street, #N276
San Francisco CA 94158
Phone415-476-8748
PronounsHe/Him/His
ORCID ORCID Icon0000-0001-8562-6552 Additional info
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    Collapse Biography 
    Collapse education and training
    Vanderbilt University, Nashville, TNPh.D.12/2020Pharmacology
    University of Arizona, Tucson, AZB.S./B.S.8/2014Biochemistry/Molecular and Cellular Biology
    Collapse awards and honors
    NIH/NIDDK2018  - 2020Ruth L. Kirschstein National Research Service Award (1F31DK120225-01)

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun. 2023 08 12; 14(1):4874. Feng S, Puchades C, Ko J, Wu H, Chen Y, Figueroa EE, Gu S, Han TW, Ho B, Cheng T, Li J, Shoichet B, Jan YN, Cheng Y, Jan LY. PMID: 37573365; PMCID: PMC10423226.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    2. A SWELL time to develop the molecular pharmacology of the volume-regulated anion channel (VRAC). Channels (Austin). 2022 12; 16(1):27-36. Figueroa EE, Denton JS. PMID: 35114895; PMCID: PMC8820792.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    3. Identification of a conserved drug binding pocket in TMEM16 proteins. Res Sq. 2022 Feb 10. Cheng Y, Feng S, Puchades C, Ko J, Figueroa E, Chen Y, Wu H, Gu S, Han T, Li J, Ho B, Shoichet B, Jan YN, Jan L. PMID: 35169791; PMCID: PMC8845511.
      View in: PubMed   Mentions:
    4. Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism. Am J Physiol Cell Physiol. 2021 06 01; 320(6):C1088-C1098. Figueroa EE, Denton JS. PMID: 33826406; PMCID: PMC8285639.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    5. LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology. Am J Physiol Cell Physiol. 2021 03 01; 320(3):C293-C303. Yamada T, Figueroa EE, Denton JS, Strange K. PMID: 33356947; PMCID: PMC8294627.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    6. The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel. Physiol Rep. 2019 12; 7(23):e14303. Afzal A, Figueroa EE, Kharade SV, Bittman K, Matlock BK, Flaherty DK, Denton JS. PMID: 31814333; PMCID: PMC6900491.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    7. CysLT1 receptor antagonists pranlukast and zafirlukast inhibit LRRC8-mediated volume regulated anion channels independently of the receptor. Am J Physiol Cell Physiol. 2019 10 01; 317(4):C857-C866. Figueroa EE, Kramer M, Strange K, Denton JS. PMID: 31390227; PMCID: PMC6850990.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    8. Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992. Mol Pharmacol. 2018 08; 94(2):926-937. Kharade SV, Kurata H, Bender AM, Blobaum AL, Figueroa EE, Duran A, Kramer M, Days E, Vinson P, Flores D, Satlin LM, Meiler J, Weaver CD, Lindsley CW, Hopkins CR, Denton JS. PMID: 29895592; PMCID: PMC6041953.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    9. Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590. Mol Pharmacol. 2017 09; 92(3):338-346. Kharade SV, Sheehan JH, Figueroa EE, Meiler J, Denton JS. PMID: 28619748; PMCID: PMC5553192.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    10. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. ACS Chem Neurosci. 2016 07 20; 7(7):1013-23. Swale DR, Kurata H, Kharade SV, Sheehan J, Raphemot R, Voigtritter KR, Figueroa EE, Meiler J, Blobaum AL, Lindsley CW, Hopkins CR, Denton JS. PMID: 27184474; PMCID: PMC5131535.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
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