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Alan Verkman, MD, PhD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentMedicine
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-476-8530
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    Collapse Biography 
    Collapse Education and Training
    M.I.T.S.B., S.B.Physics, Biology
    Harvard UniversityM.A., Ph.D.Physics
    Harvard Medical School / HSTM.D.
    Brigham & Womens HospitalResidency Medicine
    University of California, San FranciscoFellowship Nephrology

    Collapse Research 
    Collapse Research Activities and Funding
    Urea transport inhibitors as a new class of diuretics
    NIH/NIDDK R01DK101373Apr 1, 2014 - Mar 31, 2019
    Role: Principal Investigator
    CFTR inhibitors for therapy of polycystic kidney disease
    NIH/NIDDK RC1DK086125Sep 25, 2009 - Jul 31, 2012
    Role: Principal Investigator
    Novel Small-Molecule Therapies for CF
    NIH/NIDDK P30DK072517Sep 15, 2005 - May 31, 2020
    Role: Principal Investigator
    Role of airway submucosal glands in CF lung disease
    NIH/NHLBI R01HL073856Sep 1, 2003 - Aug 31, 2013
    Role: Principal Investigator
    Aquaporin-4 in NMO Optic Neuritis: Pathogenesis and New Therapies
    NIH/NEI R01EY013574Jul 1, 2001 - Apr 30, 2018
    Role: Principal Investigator
    Physiology and Molecular Biology of Lung Water Transport
    NIH/NHLBI R01HL059198Sep 1, 1998 - Jul 31, 2009
    Role: Principal Investigator
    ALTERATIONS IN AIRWAY SURFACE LIQUID IN CYSTIC FIBROSIS
    NIH P50HL060288Sep 1, 1998 - Aug 31, 2003
    Role: Co-Investigator
    Application of Novel Optical Methods to Cell Dynamics
    NIH/NIBIB R37EB000415Jul 1, 1997 - Mar 31, 2017
    Role: Principal Investigator
    Application of Novel Optical Methods to Cell Dynamics
    NIH/NIBIB R01EB000415Jul 1, 1997 - Mar 31, 2007
    Role: Principal Investigator
    MECHANISMS OF WATER TRANSPORT IN RENAL EPITHELIA
    NIH/FIC R03TW000704Sep 1, 1996 - Aug 31, 2000
    Role: Principal Investigator
    APPLICATION OF NOVEL OPTICAL METHODS TO CELL DYNAMICS
    NIH/NIDDK R01DK043840Feb 1, 1993 - Jan 31, 2002
    Role: Principal Investigator
    DEVELOPMENT OF CHLORIDE-SENSITIVE FLUORESCENT INDICATORS
    NIH/NIDDK R01DK039354Apr 1, 1988 - Mar 31, 1992
    Role: Principal Investigator
    Mechanisms of water transport in renal epithelia
    NIH/NIDDK R01DK035124Jan 1, 1986 - Jun 30, 2015
    Role: Principal Investigator
    MECHANISMS OF WATER TRANSPORT IN RENAL EPITHELIA
    NIH/NIDDK R37DK035124Jan 1, 1986 - May 31, 2010
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    CF pathogenesis mechanisms and therapies
    Cystic Fibrosis Foundation
    Role: PI
    Neuromyelitis Optica: Disease Mechanisms & New Therapies
    Guthy-Jackson Charitable Foundation
    Role: PI

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Lee S, Phuan PW, Felix CM, Tan JA, Levin MH, Verkman A. Nanomolar-potency aminophenyl-1,3,5-triazine activators of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel for pro-secretory therapy of dry eye diseases. J Med Chem. 2017 Jan 18. PMID: 28099811.
      View in: PubMed
    2. Thiagarajah JR, Chang J, Goettel JA, Verkman A, Lencer WI. Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia. Proc Natl Acad Sci U S A. 2017 Jan 03. PMID: 28049834.
      View in: PubMed
    3. Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman A, Steinman L, Green AJ, Anderson MS, Sobel RA, Zamvil SS. Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4. Proc Natl Acad Sci U S A. 2016 Dec 20; 113(51):14781-14786. PMID: 27940915.
      View in: PubMed
    4. Haggie PM, Phuan PW, Tan JA, Xu H, Avramescu RG, Perdomo D, Zlock L, Nielson DW, Finkbeiner WE, Lukacs GL, Verkman A. Correctors and Potentiators Rescue Function of the Truncated W1282X-CFTR Translation Product. J Biol Chem. 2016 Nov 28. PMID: 27895116.
      View in: PubMed
    5. Jin BJ, Smith AJ, Verkman A. Spatial model of convective solute transport in brain extracellular space does not support a "glymphatic" mechanism. J Gen Physiol. 2016 Nov 11. PMID: 27836940.
      View in: PubMed
    6. Cil O, Phuan PW, Gillespie AM, Lee S, Tradtrantip L, Yin J, Tse M, Zachos NC, Lin R, Donowitz M, Verkman A. Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for anti-secretory therapy of diarrheas caused by bacterial enterotoxins. FASEB J. 2016 Nov 8. PMID: 27871064.
      View in: PubMed
    7. Felix CM, Levin MH, Verkman A. Complement-independent retinal pathology produced by intravitreal injection of neuromyelitis optica immunoglobulin G. J Neuroinflammation. 2016 Oct 20; 13(1):275. PMID: 27765056.
      View in: PubMed
    8. Cil O, Phuan PW, Son JH, Zhu JS, Ku CK, Tabib NA, Teuthorn AP, Ferrera L, Zachos NC, Lin R, Galietta LJ, Donowitz M, Kurth MJ, Verkman A. Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation. Transl Res. 2016 Oct 15. PMID: 27815136.
      View in: PubMed
    9. Reed GD, von Morze C, Verkman A, Koelsch BL, Chaumeil MM, Lustig M, Ronen SM, Bok RA, Sands JM, Larson PE, Wang ZJ, Larsen JH, Kurhanewicz J, Vigneron DB, et al. Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry. Tomography. 2016 Jun; 2(2):125-135. PMID: 27570835.
      View in: PubMed
    10. Tradtrantip L, Verkman A. Aquaporin gene therapy for disorders of cholestasis? Hepatology. 2016 Aug; 64(2):344-6. PMID: 27115396.
      View in: PubMed
    11. Ikezoe K, Oga T, Honda T, Hara-Chikuma M, Ma X, Tsuruyama T, Uno K, Fuchikami J, Tanizawa K, Handa T, Taguchi Y, Verkman A, Narumiya S, Mishima M, Chin K. Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma. Sci Rep. 2016; 6:25781. PMID: 27165276.
      View in: PubMed
    12. Cil O, Haggie PM, Phuan PW, Tan JA, Verkman A, et al. Small-Molecule Inhibitors of Pendrin Potentiate the Diuretic Action of Furosemide. J Am Soc Nephrol. 2016 May 6. PMID: 27153921.
      View in: PubMed
    13. Yao X, Su T, Verkman A. Clobetasol promotes remyelination in a mouse model of neuromyelitis optica. Acta Neuropathol Commun. 2016; 4(1):42. PMID: 27117475.
      View in: PubMed
    14. Esteva-Font C, Jin BJ, Lee S, Phuan PW, Anderson MO, Verkman A. Experimental Evaluation of Proposed Small-Molecule Inhibitors of Water Channel Aquaporin-1. Mol Pharmacol. 2016 Jun; 89(6):686-93. PMID: 26993802.
      View in: PubMed
    15. Haggie PM, Phuan PW, Tan JA, Zlock L, Finkbeiner WE, Verkman A. Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis. FASEB J. 2016 Jun; 30(6):2187-97. PMID: 26932931.
      View in: PubMed
    16. Flores AM, Casey SD, Felix CM, Phuan PW, Verkman A, Levin MH. Small-molecule CFTR activators increase tear secretion and prevent experimental dry eye disease. FASEB J. 2016 May; 30(5):1789-97. PMID: 26842854.
      View in: PubMed
    17. Piechowicz KA, Truong EC, Javed KM, Chaney RR, Wu JY, Phuan PW, Verkman A, Anderson MO. Synthesis and evaluation of 5,6-disubstituted thiopyrimidine aryl aminothiazoles as inhibitors of the calcium-activated chloride channel TMEM16A/Ano1. J Enzyme Inhib Med Chem. 2016 Dec; 31(6):1362-8. PMID: 26796863; PMCID: PMC4958041 [Available on 07/22/17].
    18. Hirt L, Fukuda AM, Ambadipudi K, Rashid F, Binder D, Verkman A, Ashwal S, Obenaus A, Badaut J. Improved long-term outcome after transient cerebral ischemia in aquaporin-4 knockout mice. J Cereb Blood Flow Metab. 2016 Jan 14. PMID: 26767580.
      View in: PubMed
    19. Cil O, Phuan PW, Lee S, Tan J, Haggie PM, Levin MH, Sun L, Thiagarajah JR, Ma T, Verkman A, et al. CFTR activator increases intestinal fluid secretion and normalizes stool output in a mouse model of constipation. Cell Mol Gastroenterol Hepatol. 2016 May; 2(3):317-327. PMID: 27127798.
      View in: PubMed
    20. Smith AJ, Verkman A. Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections. Biophys J. 2015 Dec 15; 109(12):2511-22. PMID: 26682810.
      View in: PubMed
    21. Verkman A, Edelman A, Amaral M, Mall MA, Beekman JM, Meiners T, Galietta LJ, Bear CE. Finding new drugs to enhance anion secretion in cystic fibrosis: Toward suitable systems for better drug screening. Report on the pre-conference meeting to the 12th ECFS Basic Science Conference, Albufeira, 25-28 March 2015. J Cyst Fibros. 2015 Nov; 14(6):700-5. PMID: 26474804.
      View in: PubMed
    22. Jo AO, Ryskamp DA, Phuong TT, Verkman A, Yarishkin O, MacAulay N, Križaj D. TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia. J Neurosci. 2015 Sep 30; 35(39):13525-37. PMID: 26424896; PMCID: PMC4588615 [Available on 03/30/16].
    23. Jin BJ, Esteva-Font C, Verkman A. Droplet-based microfluidic platform for measurement of rapid erythrocyte water transport. Lab Chip. 2015 Aug 21; 15(16):3380-90. PMID: 26159099.
      View in: PubMed
    24. Phuan PW, Veit G, Tan JA, Finkbeiner WE, Lukacs GL, Verkman A. Potentiators of Defective ?F508-CFTR Gating that Do Not Interfere with Corrector Action. Mol Pharmacol. 2015 Oct; 88(4):791-9. PMID: 26245207; PMCID: PMC4576684 [Available on 10/01/16].
    25. Kim Y, Anderson MO, Park J, Lee MG, Namkung W, Verkman A. Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATP. Mol Pharmacol. 2015 Oct; 88(4):689-96. PMID: 26174774; PMCID: PMC4576686 [Available on 10/01/16].
    26. Thiagarajah JR, Donowitz M, Verkman A. Secretory diarrhoea: mechanisms and emerging therapies. Nat Rev Gastroenterol Hepatol. 2015 Aug; 12(8):446-57. PMID: 26122478.
      View in: PubMed
    27. Hara-Chikuma M, Satooka H, Watanabe S, Honda T, Miyachi Y, Watanabe T, Verkman A. Aquaporin-3-mediated hydrogen peroxide transport is required for NF-?B signalling in keratinocytes and development of psoriasis. Nat Commun. 2015; 6:7454. PMID: 26100668.
      View in: PubMed
    28. Yao X, Uchida K, Papadopoulos MC, Zador Z, Manley GT, Verkman A. Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury. J Neurotrauma. 2015 Oct 1; 32(19):1458-64. PMID: 25790314; PMCID: PMC4589265 [Available on 10/01/16].
    29. Cil O, Esteva-Font C, Tas ST, Su T, Lee S, Anderson MO, Ertunc M, Verkman A. Salt-sparing diuretic action of a water-soluble urea analog inhibitor of urea transporters UT-A and UT-B in rats. Kidney Int. 2015 Aug; 88(2):311-20. PMID: 25993324; PMCID: PMC4523423 [Available on 02/01/16].
    30. Smith AJ, Jin BJ, Verkman A. Muddying the water in brain edema? Trends Neurosci. 2015 Jun; 38(6):331-2. PMID: 25980601.
      View in: PubMed
    31. Yao X, Smith AJ, Jin BJ, Zador Z, Manley GT, Verkman A. Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice. Glia. 2015 Oct; 63(10):1860-9. PMID: 25944186.
      View in: PubMed
    32. Owens GP, Ritchie A, Rossi A, Schaller K, Wemlinger S, Schumann H, Shearer A, Verkman A, Bennett JL. Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG. J Biol Chem. 2015 May 8; 290(19):12123-34. PMID: 25792738; PMCID: PMC4424347.
    33. Esteva-Font C, Phuan PW, Lee S, Su T, Anderson MO, Verkman A. Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters. Biochim Biophys Acta. 2015 May; 1848(5):1075-80. PMID: 25613743; PMCID: PMC4364388 [Available on 05/01/16].
    34. Zhang H, Verkman A. Aquaporin-1 water permeability as a novel determinant of axonal regeneration in dorsal root ganglion neurons. Exp Neurol. 2015 Mar; 265:152-9. PMID: 25585012; PMCID: PMC4346453 [Available on 03/01/16].
    35. Wang W, Li F, Sun Y, Lei L, Zhou H, Lei T, Xia Y, Verkman A, Yang B. Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling. FASEB J. 2015 Apr; 29(4):1551-63. PMID: 25573755; PMCID: PMC4396615 [Available on 04/01/16].
    36. Lee S, Esteva-Font C, Phuan PW, Anderson MO, Verkman A. Discovery, synthesis and structure-activity analysis of symmetrical 2,7-disubstituted fluorenones as urea transporter inhibitors. Medchemcomm. 2015; 6:1278-1284. PMID: 26191399.
      View in: PubMed
    37. Esteva-Font C, Anderson MO, Verkman A. Urea transporter proteins as targets for small-molecule diuretics. Nat Rev Nephrol. 2015 Feb; 11(2):113-23. PMID: 25488859.
      View in: PubMed
    38. Yao X, Derugin N, Manley GT, Verkman A. Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia. Neurosci Lett. 2015 Jan 1; 584:368-72. PMID: 25449874.
      View in: PubMed
    39. Ye L, Hu B, El-Badri F, Hudson BM, Phuan PW, Verkman A, Tantillo DJ, Kurth MJ. ?F508-CFTR correctors: synthesis and evaluation of thiazole-tethered imidazolones, oxazoles, oxadiazoles, and thiadiazoles. Bioorg Med Chem Lett. 2014 Dec 15; 24(24):5840-4. PMID: 25452003; PMCID: PMC4255153 [Available on 12/15/15].
    40. Malik R, Lewis A, Cree BA, Ratelade J, Rossi A, Verkman A, Bollen AW, Ralph JW. Transient hyperckemia in the setting of neuromyelitis optica (NMO). Muscle Nerve. 2014 Nov; 50(5):859-62. PMID: 24862586; PMCID: PMC4306419.
    41. Tradtrantip L, Asavapanumas N, Phuan PW, Verkman A. Potential therapeutic benefit of C1-esterase inhibitor in neuromyelitis optica evaluated in vitro and in an experimental rat model. PLoS One. 2014; 9(9):e106824. PMID: 25191939; PMCID: PMC4156393.
    42. Papadopoulos MC, Bennett JL, Verkman A. Treatment of neuromyelitis optica: state-of-the-art and emerging therapies. Nat Rev Neurol. 2014 Sep; 10(9):493-506. PMID: 25112508; PMCID: PMC4229040.
    43. Coffman KC, Nguyen HH, Phuan PW, Hudson BM, Yu GJ, Bagdasarian AL, Montgomery D, Lodewyk MW, Yang B, Yoo CL, Verkman A, Tantillo DJ, Kurth MJ. Constrained bithiazoles: small molecule correctors of defective ?F508-CFTR protein trafficking. J Med Chem. 2014 Aug 14; 57(15):6729-38. PMID: 25061695; PMCID: PMC4136667.
    44. Veit G, Avramescu RG, Perdomo D, Phuan PW, Bagdany M, Apaja PM, Borot F, Szollosi D, Wu YS, Finkbeiner WE, Hegedus T, Verkman A, Lukacs GL. Some gating potentiators, including VX-770, diminish ?F508-CFTR functional expression. Sci Transl Med. 2014 Jul 23; 6(246):246ra97. PMID: 25101887; PMCID: PMC4467693.
    45. Ratelade J, Verkman A. Inhibitor(s) of the classical complement pathway in mouse serum limit the utility of mice as experimental models of neuromyelitis optica. Mol Immunol. 2014 Nov; 62(1):104-13. PMID: 24980869; PMCID: PMC4306420.
    46. Esteva-Font C, Cil O, Phuan PW, Su T, Lee S, Anderson MO, Verkman A. Diuresis and reduced urinary osmolality in rats produced by small-molecule UT-A-selective urea transport inhibitors. FASEB J. 2014 Sep; 28(9):3878-90. PMID: 24843071; PMCID: PMC4139901.
    47. Asavapanumas N, Verkman A. Neuromyelitis optica pathology in rats following intraperitoneal injection of NMO-IgG and intracerebral needle injury. Acta Neuropathol Commun. 2014; 2:48. PMID: 24758159; PMCID: PMC4234989.
    48. Phuan PW, Veit G, Tan J, Roldan A, Finkbeiner WE, Lukacs GL, Verkman A. Synergy-based small-molecule screen using a human lung epithelial cell line yields ?F508-CFTR correctors that augment VX-809 maximal efficacy. Mol Pharmacol. 2014 Jul; 86(1):42-51. PMID: 24737137; PMCID: PMC4054004.
    49. Akdemir G, Ratelade J, Asavapanumas N, Verkman A. Neuroprotective effect of aquaporin-4 deficiency in a mouse model of severe global cerebral ischemia produced by transient 4-vessel occlusion. Neurosci Lett. 2014 Jun 27; 574:70-5. PMID: 24717641; PMCID: PMC4306422.
    50. Jin BJ, Battula S, Zachos N, Kovbasnjuk O, Fawlke-Abel J, In J, Donowitz M, Verkman A. Microfluidics platform for measurement of volume changes in immobilized intestinal enteroids. Biomicrofluidics. 2014 Mar; 8(2):024106. PMID: 24738013; PMCID: PMC3976466.
    51. Zhang H, Verkman A. Longitudinally extensive NMO spinal cord pathology produced by passive transfer of NMO-IgG in mice lacking complement inhibitor CD59. J Autoimmun. 2014 Sep; 53:67-77. PMID: 24698947; PMCID: PMC4162764.
    52. Ratelade J, Smith AJ, Verkman A. Human immunoglobulin G reduces the pathogenicity of aquaporin-4 autoantibodies in neuromyelitis optica. Exp Neurol. 2014 May; 255:145-53. PMID: 24636863; PMCID: PMC4291172.
    53. Verkman A, Anderson MO, Papadopoulos MC. Aquaporins: important but elusive drug targets. Nat Rev Drug Discov. 2014 Apr; 13(4):259-77. PMID: 24625825; PMCID: PMC4067137.
    54. Tradtrantip L, Ko EA, Verkman A. Antidiarrheal efficacy and cellular mechanisms of a Thai herbal remedy. PLoS Negl Trop Dis. 2014 Feb; 8(2):e2674. PMID: 24551253; PMCID: PMC3923670.
    55. Smith AJ, Jin BJ, Ratelade J, Verkman A. Aggregation state determines the localization and function of M1- and M23-aquaporin-4 in astrocytes. J Cell Biol. 2014 Feb 17; 204(4):559-73. PMID: 24515349; PMCID: PMC3926963.
    56. Asavapanumas N, Ratelade J, Papadopoulos MC, Bennett JL, Levin MH, Verkman A. Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G. J Neuroinflammation. 2014; 11:16. PMID: 24468108; PMCID: PMC3909205.
    57. Verkman A, Esteva-Font C, Cil O, Anderson MO, Li F, Li M, Lei T, Ren H, Yang B. Small-molecule inhibitors of urea transporters. Subcell Biochem. 2014; 73:165-77. PMID: 25298345; PMCID: PMC4306426.
    58. Esteva-Font C, Jin BJ, Verkman A. Aquaporin-1 gene deletion reduces breast tumor growth and lung metastasis in tumor-producing MMTV-PyVT mice. FASEB J. 2014 Mar; 28(3):1446-53. PMID: 24334548; PMCID: PMC3929666.
    59. Rama Rao KV, Verkman A, Curtis KM, Norenberg MD. Aquaporin-4 deletion in mice reduces encephalopathy and brain edema in experimental acute liver failure. Neurobiol Dis. 2014 Mar; 63:222-8. PMID: 24321433; PMCID: PMC3982919.
    60. Thiagarajah JR, Ko EA, Tradtrantip L, Donowitz M, Verkman A. Discovery and development of antisecretory drugs for treating diarrheal diseases. Clin Gastroenterol Hepatol. 2014 Feb; 12(2):204-9. PMID: 24316107; PMCID: PMC3935719.
    61. Blanchard E, Zlock L, Lao A, Mika D, Namkung W, Xie M, Scheitrum C, Gruenert DC, Verkman A, Finkbeiner WE, Conti M, Richter W. Anchored PDE4 regulates chloride conductance in wild-type and ?F508-CFTR human airway epithelia. FASEB J. 2014 Feb; 28(2):791-801. PMID: 24200884; PMCID: PMC3898646.
    62. Asavapanumas N, Ratelade J, Verkman A. Unique neuromyelitis optica pathology produced in naïve rats by intracerebral administration of NMO-IgG. Acta Neuropathol. 2014 Apr; 127(4):539-51. PMID: 24190619; PMCID: PMC3954950.
    63. Katada R, Akdemir G, Asavapanumas N, Ratelade J, Zhang H, Verkman A. Greatly improved survival and neuroprotection in aquaporin-4-knockout mice following global cerebral ischemia. FASEB J. 2014 Feb; 28(2):705-14. PMID: 24186965; PMCID: PMC3898642.
    64. Verkman A, Phuan PW, Asavapanumas N, Tradtrantip L. Biology of AQP4 and anti-AQP4 antibody: therapeutic implications for NMO. Brain Pathol. 2013 Nov; 23(6):684-95. PMID: 24118484; PMCID: PMC3890327.
    65. Singh V, Yang J, Chen TE, Zachos NC, Kovbasnjuk O, Verkman A, Donowitz M. Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption. Clin Gastroenterol Hepatol. 2014 Jan; 12(1):27-31. PMID: 24184676; PMCID: PMC3926754.
    66. Jin BJ, Ko EA, Namkung W, Verkman A. Microfluidics platform for single-shot dose-response analysis of chloride channel-modulating compounds. Lab Chip. 2013 Oct 7; 13(19):3862-7. PMID: 23907501; PMCID: PMC3904508.
    67. Esteva-Font C, Phuan PW, Anderson MO, Verkman A. A small molecule screen identifies selective inhibitors of urea transporter UT-A. Chem Biol. 2013 Oct 24; 20(10):1235-44. PMID: 24055006; PMCID: PMC3890325.
    68. Ko EA, Jin BJ, Namkung W, Ma T, Thiagarajah JR, Verkman A. Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice. Gut. 2014 Jul; 63(7):1120-9. PMID: 24052273; PMCID: PMC4048772.
    69. Ratelade J, Asavapanumas N, Ritchie AM, Wemlinger S, Bennett JL, Verkman A. Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica. Acta Neuropathol. 2013 Nov; 126(5):699-709. PMID: 23995423; PMCID: PMC3890328.
    70. Thiagarajah JR, Verkman A. Chloride channel-targeted therapy for secretory diarrheas. Curr Opin Pharmacol. 2013 Dec; 13(6):888-94. PMID: 23992767; PMCID: PMC3890324.
    71. Valentine CD, Zhang H, Phuan PW, Nguyen J, Verkman A, Haggie PM. Small molecule screen yields inhibitors of Pseudomonas homoserine lactone-induced host responses. Cell Microbiol. 2014 Jan; 16(1):1-14. PMID: 23910799; PMCID: PMC3909729.
    72. Verkman A. Diffusion in the extracellular space in brain and tumors. Phys Biol. 2013 Aug 02; 10(4):045003. PMID: 23913007.
      View in: PubMed
    73. Jin BJ, Thiagarajah JR, Verkman A. Response to "Diffusion versus convection". J Gen Physiol. 2013 Aug; 142(2):173. PMID: 23898009; PMCID: PMC3727305.
    74. Rowe SM, Verkman A. Cystic fibrosis transmembrane regulator correctors and potentiators. Cold Spring Harb Perspect Med. 2013 Jul; 3(7). PMID: 23818513; PMCID: PMC3685879.
    75. Namkung W, Park J, Seo Y, Verkman A. Novel amino-carbonitrile-pyrazole identified in a small molecule screen activates wild-type and ?F508 cystic fibrosis transmembrane conductance regulator in the absence of a cAMP agonist. Mol Pharmacol. 2013 Sep; 84(3):384-92. PMID: 23788656; PMCID: PMC3876813.
    76. Jin BJ, Zhang H, Binder DK, Verkman A. Response to "When can AQP4 assist transporter-mediated K? uptake?". J Gen Physiol. 2013 Jul; 142(1):91-2. PMID: 23752331; PMCID: PMC3691444.
    77. Phuan PW, Zhang H, Asavapanumas N, Leviten M, Rosenthal A, Tradtrantip L, Verkman A. C1q-targeted monoclonal antibody prevents complement-dependent cytotoxicity and neuropathology in in vitro and mouse models of neuromyelitis optica. Acta Neuropathol. 2013 Jun; 125(6):829-40. PMID: 23677375; PMCID: PMC3941651.
    78. Okiyoneda T, Veit G, Dekkers JF, Bagdany M, Soya N, Xu H, Roldan A, Verkman A, Kurth M, Simon A, Hegedus T, Beekman JM, Lukacs GL. Mechanism-based corrector combination restores ?F508-CFTR folding and function. Nat Chem Biol. 2013 Jul; 9(7):444-54. PMID: 23666117; PMCID: PMC3840170.
    79. Snyder DS, Tradtrantip L, Battula S, Yao C, Phuan PW, Fettinger JC, Kurth MJ, Verkman A. ABSOLUTE CONFIGURATION AND BIOLOGICAL PROPERTIES OF ENANTIOMERS OF CFTR INHIBITOR BPO-27. ACS Med Chem Lett. 2013 May 9; 4(5):456-459. PMID: 23814642.
      View in: PubMed
    80. Tradtrantip L, Asavapanumas N, Verkman A. Therapeutic cleavage of anti-aquaporin-4 autoantibody in neuromyelitis optica by an IgG-selective proteinase. Mol Pharmacol. 2013 Jun; 83(6):1268-75. PMID: 23571414; PMCID: PMC3657102.
    81. Zhang H, Verkman A. Eosinophil pathogenicity mechanisms and therapeutics in neuromyelitis optica. J Clin Invest. 2013 May; 123(5):2306-16. PMID: 23563310; PMCID: PMC3635742.
    82. Liu Y, Esteva-Font C, Yao C, Phuan PW, Verkman A, Anderson MO. 1,1-Difluoroethyl-substituted triazolothienopyrimidines as inhibitors of a human urea transport protein (UT-B): new analogs and binding model. Bioorg Med Chem Lett. 2013 Jun 1; 23(11):3338-41. PMID: 23597791; PMCID: PMC3954708.
    83. Levin MH, Bennett JL, Verkman A. Optic neuritis in neuromyelitis optica. Prog Retin Eye Res. 2013 Sep; 36:159-71. PMID: 23545439; PMCID: PMC3770284.
    84. Papadopoulos MC, Verkman A. Aquaporin water channels in the nervous system. Nat Rev Neurosci. 2013 Apr; 14(4):265-77. PMID: 23481483; PMCID: PMC3732112.
    85. Jin BJ, Thiagarajah JR, Verkman A. Convective washout reduces the antidiarrheal efficacy of enterocyte surface-targeted antisecretory drugs. J Gen Physiol. 2013 Feb; 141(2):261-72. PMID: 23359285; PMCID: PMC3557305.
    86. Davis AJ, Shi J, Pritchard HA, Chadha PS, Leblanc N, Vasilikostas G, Yao Z, Verkman A, Albert AP, Greenwood IA. Potent vasorelaxant activity of the TMEM16A inhibitor T16A(inh) -A01. Br J Pharmacol. 2013 Feb; 168(3):773-84. PMID: 22946562; PMCID: PMC3579294.
    87. Verkman A. Aquaporins. Curr Biol. 2013 Jan 21; 23(2):R52-5. PMID: 23347934; PMCID: PMC3590904.
    88. Verkman A, Synder D, Tradtrantip L, Thiagarajah JR, Anderson MO. CFTR inhibitors. Curr Pharm Des. 2013; 19(19):3529-41. PMID: 23331030; PMCID: PMC4012685.
    89. Jin BJ, Zhang H, Binder DK, Verkman A. Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation. J Gen Physiol. 2013 Jan; 141(1):119-32. PMID: 23277478; PMCID: PMC3536523.
    90. Saadoun S, Bridges LR, Verkman A, Papadopoulos MC. Paucity of natural killer and cytotoxic T cells in human neuromyelitis optica lesions. Neuroreport. 2012 Dec 19; 23(18):1044-7. PMID: 23108041; PMCID: PMC3590012.
    91. Valentine CD, Lukacs GL, Verkman A, Haggie PM. Reduced PDZ interactions of rescued ?F508CFTR increases its cell surface mobility. J Biol Chem. 2012 Dec 21; 287(52):43630-8. PMID: 23115232; PMCID: PMC3527949.
    92. Tradtrantip L, Ratelade J, Zhang H, Verkman A. Enzymatic deglycosylation converts pathogenic neuromyelitis optica anti-aquaporin-4 immunoglobulin G into therapeutic antibody. Ann Neurol. 2013 Jan; 73(1):77-85. PMID: 23055279; PMCID: PMC3567850.
    93. Phuan PW, Anderson MO, Tradtrantip L, Zhang H, Tan J, Lam C, Bennett JL, Verkman A. A small-molecule screen yields idiotype-specific blockers of neuromyelitis optica immunoglobulin G binding to aquaporin-4. J Biol Chem. 2012 Oct 26; 287(44):36837-44. PMID: 22989877; PMCID: PMC3481286.
    94. Rossi A, Ratelade J, Papadopoulos MC, Bennett JL, Verkman A. Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly. Glia. 2012 Dec; 60(12):2027-39. PMID: 22987455; PMCID: PMC3586219.
    95. Veit G, Bossard F, Goepp J, Verkman A, Galietta LJ, Hanrahan JW, Lukacs GL. Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell. 2012 Nov; 23(21):4188-202. PMID: 22973054; PMCID: PMC3484098.
    96. Hara-Chikuma M, Chikuma S, Sugiyama Y, Kabashima K, Verkman A, Inoue S, Miyachi Y. Chemokine-dependent T cell migration requires aquaporin-3-mediated hydrogen peroxide uptake. J Exp Med. 2012 Sep 24; 209(10):1743-52. PMID: 22927550; PMCID: PMC3457725.
    97. Thiagarajah JR, Verkman A. CFTR inhibitors for treating diarrheal disease. Clin Pharmacol Ther. 2012 Sep; 92(3):287-90. PMID: 22850599; PMCID: PMC3643514.
    98. Donald MB, Rodriguez KX, Shay H, Phuan PW, Verkman A, Kurth MJ. Click-based synthesis of triazolobithiazole ?F508-CFTR correctors for cystic fibrosis. Bioorg Med Chem. 2012 Sep 1; 20(17):5247-53. PMID: 22841006; PMCID: PMC3419814.
    99. Rossi A, Moritz TJ, Ratelade J, Verkman A. Super-resolution imaging of aquaporin-4 orthogonal arrays of particles in cell membranes. J Cell Sci. 2012 Sep 15; 125(Pt 18):4405-12. PMID: 22718347; PMCID: PMC3516444.
    100. Anderson MO, Zhang J, Liu Y, Yao C, Phuan PW, Verkman A. Nanomolar potency and metabolically stable inhibitors of kidney urea transporter UT-B. J Med Chem. 2012 Jun 28; 55(12):5942-50. PMID: 22694147; PMCID: PMC3590912.
    101. Ratelade J, Verkman A. Neuromyelitis optica: aquaporin-4 based pathogenesis mechanisms and new therapies. Int J Biochem Cell Biol. 2012 Sep; 44(9):1519-30. PMID: 22713791; PMCID: PMC3676174.
    102. Kumar S, Namkung W, Verkman A, Sharma PK. Novel 5-substituted benzyloxy-2-arylbenzofuran-3-carboxylic acids as calcium activated chloride channel inhibitors. Bioorg Med Chem. 2012 Jul 15; 20(14):4237-44. PMID: 22739085; PMCID: PMC3643516.
    103. Yao Z, Namkung W, Ko EA, Park J, Tradtrantip L, Verkman A. Fractionation of a herbal antidiarrheal medicine reveals eugenol as an inhibitor of Ca2+-Activated Cl- channel TMEM16A. PLoS One. 2012; 7(5):e38030. PMID: 22666439; PMCID: PMC3364195.
    104. Papadopoulos MC, Verkman A. Aquaporin 4 and neuromyelitis optica. Lancet Neurol. 2012 Jun; 11(6):535-44. PMID: 22608667; PMCID: PMC3678971.
    105. Rossi A, Ratelade J, Papadopoulos MC, Bennett JL, Verkman A. Consequences of NMO-IgG binding to aquaporin-4 in neuromyelitis optica. Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24):E1511; author reply E1512. PMID: 22589299; PMCID: PMC3386066.
    106. Ratelade J, Zhang H, Saadoun S, Bennett JL, Papadopoulos MC, Verkman A. Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss. Acta Neuropathol. 2012 Jun; 123(6):861-72. PMID: 22526022; PMCID: PMC3581313.
    107. Yao C, Anderson MO, Zhang J, Yang B, Phuan PW, Verkman A. Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration. J Am Soc Nephrol. 2012 Jul; 23(7):1210-20. PMID: 22491419; PMCID: PMC3380644.
    108. Phuan PW, Ratelade J, Rossi A, Tradtrantip L, Verkman A. Complement-dependent cytotoxicity in neuromyelitis optica requires aquaporin-4 protein assembly in orthogonal arrays. J Biol Chem. 2012 Apr 20; 287(17):13829-39. PMID: 22393049; PMCID: PMC3340190.
    109. Saadoun S, Waters P, MacDonald C, Bell BA, Vincent A, Verkman A, Papadopoulos MC. Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain. Ann Neurol. 2012 Mar; 71(3):323-33. PMID: 22374891; PMCID: PMC3643520.
    110. Tradtrantip L, Zhang H, Anderson MO, Saadoun S, Phuan PW, Papadopoulos MC, Bennett JL, Verkman A. Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica. FASEB J. 2012 May; 26(5):2197-208. PMID: 22319008; PMCID: PMC3336779.
    111. Knapp JM, Wood AB, Phuan PW, Lodewyk MW, Tantillo DJ, Verkman A, Kurth MJ. Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in ?F508 cystic fibrosis transmembrane conductance regulator protein. J Med Chem. 2012 Feb 9; 55(3):1242-51. PMID: 22214395; PMCID: PMC3277286.
    112. Tradtrantip L, Zhang H, Saadoun S, Phuan PW, Lam C, Papadopoulos MC, Bennett JL, Verkman A. Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Ann Neurol. 2012 Mar; 71(3):314-22. PMID: 22271321; PMCID: PMC3314396.
    113. Davison HR, Solano DM, Phuan PW, Verkman A, Kurth MJ. Fluorinated ?F508-CFTR correctors and potentiators for PET imaging. Bioorg Med Chem Lett. 2012 Feb 15; 22(4):1602-5. PMID: 22281185; PMCID: PMC3274619.
    114. Verkman A. Aquaporins in clinical medicine. Annu Rev Med. 2012; 63:303-16. PMID: 22248325; PMCID: PMC3319404.
    115. Baumgart F, Rossi A, Verkman A. Light inactivation of water transport and protein-protein interactions of aquaporin-Killer Red chimeras. J Gen Physiol. 2012 Jan; 139(1):83-91. PMID: 22200949; PMCID: PMC3250104.
    116. Verkman A, Rossi A, Crane JM. Live-cell imaging of aquaporin-4 supramolecular assembly and diffusion. Methods Enzymol. 2012; 504:341-54. PMID: 22264543; PMCID: PMC3579562.
    117. Lukacs GL, Verkman A. CFTR: folding, misfolding and correcting the ?F508 conformational defect. Trends Mol Med. 2012 Feb; 18(2):81-91. PMID: 22138491; PMCID: PMC3643519.
    118. Davison HR, Taylor S, Drake C, Phuan PW, Derichs N, Yao C, Jones EF, Sutcliffe J, Verkman A, Kurth MJ. Functional fluorescently labeled bithiazole ?F508-CFTR corrector imaged in whole body slices in mice. Bioconjug Chem. 2011 Dec 21; 22(12):2593-9. PMID: 22034937; PMCID: PMC3245868.
    119. Zhang H, Bennett JL, Verkman A. Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms. Ann Neurol. 2011 Dec; 70(6):943-54. PMID: 22069219; PMCID: PMC3319401.
    120. Ratelade J, Bennett JL, Verkman A. Evidence against cellular internalization in vivo of NMO-IgG, aquaporin-4, and excitatory amino acid transporter 2 in neuromyelitis optica. J Biol Chem. 2011 Dec 30; 286(52):45156-64. PMID: 22069320; PMCID: PMC3247969.
    121. Rossi A, Baumgart F, van Hoek AN, Verkman A. Post-Golgi supramolecular assembly of aquaporin-4 in orthogonal arrays. Traffic. 2012 Jan; 13(1):43-53. PMID: 21981006; PMCID: PMC3319398.
    122. Ratelade J, Bennett JL, Verkman A. Intravenous neuromyelitis optica autoantibody in mice targets aquaporin-4 in peripheral organs and area postrema. PLoS One. 2011; 6(11):e27412. PMID: 22076159; PMCID: PMC3208637.
    123. Valentine CD, Verkman A, Haggie PM. Protein trafficking rates assessed by quantum dot quenching with bromocresol green. Traffic. 2012 Jan; 13(1):25-9. PMID: 21951589; PMCID: PMC3237755.
    124. Namkung W, Yao Z, Finkbeiner WE, Verkman A. Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. FASEB J. 2011 Nov; 25(11):4048-62. PMID: 21836025; PMCID: PMC3205834.
    125. Snyder DS, Tradtrantip L, Yao C, Kurth MJ, Verkman A. Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease. J Med Chem. 2011 Aug 11; 54(15):5468-77. PMID: 21707078; PMCID: PMC3314378.
    126. Phuan PW, Yang B, Knapp JM, Wood AB, Lukacs GL, Kurth MJ, Verkman A. Cyanoquinolines with independent corrector and potentiator activities restore ?Phe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis. Mol Pharmacol. 2011 Oct; 80(4):683-93. PMID: 21730204; PMCID: PMC3187530.
    127. Verkman A. Aquaporins at a glance. J Cell Sci. 2011 Jul 1; 124(Pt 13):2107-12. PMID: 21670197.
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    128. Jin BJ, Rossi A, Verkman A. Model of aquaporin-4 supramolecular assembly in orthogonal arrays based on heterotetrameric association of M1-M23 isoforms. Biophys J. 2011 Jun 22; 100(12):2936-45. PMID: 21689527; PMCID: PMC3123972.
    129. Crane JM, Rossi A, Gupta T, Bennett JL, Verkman A. Orthogonal array formation by human aquaporin-4: examination of neuromyelitis optica-associated aquaporin-4 polymorphisms. J Neuroimmunol. 2011 Jul; 236(1-2):93-8. PMID: 21621278; PMCID: PMC3582392.
    130. Verkman A, Ratelade J, Rossi A, Zhang H, Tradtrantip L. Aquaporin-4: orthogonal array assembly, CNS functions, and role in neuromyelitis optica. Acta Pharmacol Sin. 2011 Jun; 32(6):702-10. PMID: 21552296; PMCID: PMC3601948.
    131. Skucas VA, Mathews IB, Yang J, Cheng Q, Treister A, Duffy AM, Verkman A, Hempstead BL, Wood MA, Binder DK, Scharfman HE. Impairment of select forms of spatial memory and neurotrophin-dependent synaptic plasticity by deletion of glial aquaporin-4. J Neurosci. 2011 Apr 27; 31(17):6392-7. PMID: 21525279; PMCID: PMC3107562.
    132. Saadoun S, Waters P, Macdonald C, Bridges LR, Bell BA, Vincent A, Verkman A, Papadopoulos MC. T cell deficiency does not reduce lesions in mice produced by intracerebral injection of NMO-IgG and complement. J Neuroimmunol. 2011 Jun; 235(1-2):27-32. PMID: 21492943.
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    133. Rossi A, Crane JM, Verkman A. Aquaporin-4 Mz isoform: brain expression, supramolecular assembly and neuromyelitis optica antibody binding. Glia. 2011 Jul; 59(7):1056-63. PMID: 21491501; PMCID: PMC3327643.
    134. Derichs N, Jin BJ, Song Y, Finkbeiner WE, Verkman A. Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching. FASEB J. 2011 Jul; 25(7):2325-32. PMID: 21427214; PMCID: PMC3114535.
    135. Crane JM, Lam C, Rossi A, Gupta T, Bennett JL, Verkman A. Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays. J Biol Chem. 2011 May 6; 286(18):16516-24. PMID: 21454592; PMCID: PMC3091256.
    136. Carpenter RD, Verkman A. Function-Oriented Synthesis of a Didesmethyl Triazacryptand Analogue for Fluorescent Potassium Ion Sensing. European J Org Chem. 2011 Mar 1; 2011(7):1242-1248. PMID: 23914138.
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    137. Li L, Zhang H, Varrin-Doyer M, Zamvil SS, Verkman A. Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation. FASEB J. 2011 May; 25(5):1556-66. PMID: 21257712; PMCID: PMC3079299.
    138. Nakahigashi K, Kabashima K, Ikoma A, Verkman A, Miyachi Y, Hara-Chikuma M. Upregulation of aquaporin-3 is involved in keratinocyte proliferation and epidermal hyperplasia. J Invest Dermatol. 2011 Apr; 131(4):865-73. PMID: 21191421.
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    139. Namkung W, Phuan PW, Verkman A. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21; 286(3):2365-74. PMID: 21084298; PMCID: PMC3023530.
    140. Wang D, Nykanen M, Yang N, Winlaw D, North K, Verkman A, Owler BK. Altered cellular localization of aquaporin-1 in experimental hydrocephalus in mice and reduced ventriculomegaly in aquaporin-1 deficiency. Mol Cell Neurosci. 2011 Jan; 46(1):318-24. PMID: 21040788.
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    141. Thiagarajah JR, Song Y, Derichs N, Verkman A. Airway surface liquid depth imaged by surface laser reflectance microscopy. J Gen Physiol. 2010 Sep; 136(3):353-62. PMID: 20713545; PMCID: PMC2931148.
    142. Zhang H, Verkman A. Microfiberoptic measurement of extracellular space volume in brain and tumor slices based on fluorescent dye partitioning. Biophys J. 2010 Aug 9; 99(4):1284-91. PMID: 20713014; PMCID: PMC2920647.
    143. Namkung W, Thiagarajah JR, Phuan PW, Verkman A. Inhibition of Ca2+-activated Cl- channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea. FASEB J. 2010 Nov; 24(11):4178-86. PMID: 20581223; PMCID: PMC2974422.
    144. Namkung W, Finkbeiner WE, Verkman A. CFTR-adenylyl cyclase I association responsible for UTP activation of CFTR in well-differentiated primary human bronchial cell cultures. Mol Biol Cell. 2010 Aug 1; 21(15):2639-48. PMID: 20554763; PMCID: PMC2912350.
    145. Kimura A, Hsu M, Seldin M, Verkman A, Scharfman HE, Binder DK. Protective role of aquaporin-4 water channels after contusion spinal cord injury. Ann Neurol. 2010 Jun; 67(6):794-801. PMID: 20517941.
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    146. Ye L, Knapp JM, Sangwung P, Fettinger JC, Verkman A, Kurth MJ. Pyrazolylthiazole as DeltaF508-cystic fibrosis transmembrane conductance regulator correctors with improved hydrophilicity compared to bithiazoles. J Med Chem. 2010 May 13; 53(9):3772-81. PMID: 20373765; PMCID: PMC3109609.
    147. Yu GJ, Yang B, Verkman A, Kurth MJ. Isoxazolopyrimidines as Novel ?F508-CFTR Correctors. Synlett. 2010 Apr 1; 2010(7):1063-1066. PMID: 23710112.
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    148. Carpenter RD, Verkman A. Synthesis of a sensitive and selective potassium-sensing fluoroionophore. Org Lett. 2010 Mar 19; 12(6):1160-3. PMID: 20148571; PMCID: PMC3315285.
    149. Tait MJ, Saadoun S, Bell BA, Verkman A, Papadopoulos MC. Increased brain edema in aqp4-null mice in an experimental model of subarachnoid hemorrhage. Neuroscience. 2010 Apr 28; 167(1):60-7. PMID: 20132873; PMCID: PMC2852644.
    150. Tajima M, Crane JM, Verkman A. Aquaporin-4 (AQP4) associations and array dynamics probed by photobleaching and single-molecule analysis of green fluorescent protein-AQP4 chimeras. J Biol Chem. 2010 Mar 12; 285(11):8163-70. PMID: 20071343; PMCID: PMC2832968.
    151. Saadoun S, Waters P, Bell BA, Vincent A, Verkman A, Papadopoulos MC. Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain. 2010 Feb; 133(Pt 2):349-61. PMID: 20047900; PMCID: PMC2822632.
    152. Crane JM, Bennett JL, Verkman A. Live cell analysis of aquaporin-4 m1/m23 interactions and regulated orthogonal array assembly in glial cells. J Biol Chem. 2009 Dec 18; 284(51):35850-60. PMID: 19843522; PMCID: PMC2791014.
    153. Zhang H, Verkman A. Aquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons. J Biol Chem. 2010 Feb 19; 285(8):5896-906. PMID: 20018876; PMCID: PMC2820815.
    154. Crane JM, Verkman A. Reversible, temperature-dependent supramolecular assembly of aquaporin-4 orthogonal arrays in live cell membranes. Biophys J. 2009 Dec 2; 97(11):3010-8. PMID: 19948131; PMCID: PMC2784574.
    155. Mills AD, Yoo C, Butler JD, Yang B, Verkman A, Kurth MJ. Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR. Bioorg Med Chem Lett. 2010 Jan 1; 20(1):87-91. PMID: 19954980; PMCID: PMC3165007.
    156. Tradtrantip L, Sonawane ND, Namkung W, Verkman A. Nanomolar potency pyrimido-pyrrolo-quinoxalinedione CFTR inhibitor reduces cyst size in a polycystic kidney disease model. J Med Chem. 2009 Oct 22; 52(20):6447-55. PMID: 19785436; PMCID: PMC3319430.
    157. Song Y, Namkung W, Nielson DW, Lee JW, Finkbeiner WE, Verkman A. Airway surface liquid depth measured in ex vivo fragments of pig and human trachea: dependence on Na+ and Cl- channel function. Am J Physiol Lung Cell Mol Physiol. 2009 Dec; 297(6):L1131-40. PMID: 19820035; PMCID: PMC2793186.
    158. Tradtrantip L, Namkung W, Verkman A. Crofelemer, an antisecretory antidiarrheal proanthocyanidin oligomer extracted from Croton lechleri, targets two distinct intestinal chloride channels. Mol Pharmacol. 2010 Jan; 77(1):69-78. PMID: 19808995; PMCID: PMC2802429.
    159. Crane JM, Tajima M, Verkman A. Live-cell imaging of aquaporin-4 diffusion and interactions in orthogonal arrays of particles. Neuroscience. 2010 Jul 28; 168(4):892-902. PMID: 19699275; PMCID: PMC3586212.
    160. Li L, Zhang H, Verkman A. Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice. BMC Neurosci. 2009; 10:94. PMID: 19660138; PMCID: PMC3152780.
    161. Verkman A. Aquaporins: translating bench research to human disease. J Exp Biol. 2009 Jun; 212(Pt 11):1707-15. PMID: 19448080; PMCID: PMC2683014.
    162. Namkung W, Song Y, Mills AD, Padmawar P, Finkbeiner WE, Verkman A. In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye. J Biol Chem. 2009 Jun 5; 284(23):15916-26. PMID: 19364771; PMCID: PMC2708887.
    163. Saadoun S, Tait MJ, Reza A, Davies DC, Bell BA, Verkman A, Papadopoulos MC. AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology. Neuroscience. 2009 Jul 7; 161(3):764-72. PMID: 19345723.
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    164. Feng X, Papadopoulos MC, Liu J, Li L, Zhang D, Zhang H, Verkman A, Ma T. Sporadic obstructive hydrocephalus in Aqp4 null mice. J Neurosci Res. 2009 Apr; 87(5):1150-5. PMID: 18951529; PMCID: PMC3582395.
    165. Haggie PM, Verkman A. Defective organellar acidification as a cause of cystic fibrosis lung disease: reexamination of a recurring hypothesis. Am J Physiol Lung Cell Mol Physiol. 2009 Jun; 296(6):L859-67. PMID: 19329540; PMCID: PMC2692795.
    166. Magzoub M, Zhang H, Dix JA, Verkman A. Extracellular space volume measured by two-color pulsed dye infusion with microfiberoptic fluorescence photodetection. Biophys J. 2009 Mar 18; 96(6):2382-90. PMID: 19289063; PMCID: PMC2907719.
    167. Ruiz-Ederra J, Verkman A. Aquaporin-1-facilitated keratocyte migration in cell culture and in vivo corneal wound healing models. Exp Eye Res. 2009 Aug; 89(2):159-65. PMID: 19298815; PMCID: PMC3319399.
    168. Crane JM, Haggie PM, Verkman A, et al. QUANTUM DOT SINGLE MOLECULE TRACKING REVEALS A WIDE RANGE OF DIFFUSIVE MOTIONS OF MEMBRANE TRANSPORT PROTEINS. Proc SPIE Int Soc Opt Eng. 2009 Mar 3; 7489. PMID: 24386532.
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    169. Crane JM, Verkman A. Determinants of aquaporin-4 assembly in orthogonal arrays revealed by live-cell single-molecule fluorescence imaging. J Cell Sci. 2009 Mar 15; 122(Pt 6):813-21. PMID: 19240114; PMCID: PMC2714425.
    170. Hara-Chikuma M, Takahashi K, Chikuma S, Verkman A, Miyachi Y. The expression of differentiation markers in aquaporin-3 deficient epidermis. Arch Dermatol Res. 2009 Mar; 301(3):245-52. PMID: 19184071; PMCID: PMC3582396.
    171. Li L, Zhang H, Ma T, Verkman A. Very high aquaporin-1 facilitated water permeability in mouse gallbladder. Am J Physiol Gastrointest Liver Physiol. 2009 Apr; 296(4):G816-22. PMID: 19179619; PMCID: PMC2670675.
    172. Ruiz-Ederra J, Levin MH, Verkman A. In situ fluorescence measurement of tear film [Na+], [K+], [Cl-], and pH in mice shows marked hypertonicity in aquaporin-5 deficiency. Invest Ophthalmol Vis Sci. 2009 May; 50(5):2132-8. PMID: 19136711; PMCID: PMC2904304.
    173. Haggie PM, Verkman A. Unimpaired lysosomal acidification in respiratory epithelial cells in cystic fibrosis. J Biol Chem. 2009 Mar 20; 284(12):7681-6. PMID: 19136560; PMCID: PMC2658062.
    174. Tradtrantip L, Tajima M, Li L, Verkman A. Aquaporin water channels in transepithelial fluid transport. J Med Invest. 2009; 56 Suppl:179-84. PMID: 20224178; PMCID: PMC3601945.
    175. Verkman A. Knock-out models reveal new aquaporin functions. Handb Exp Pharmacol. 2009; (190):359-81. PMID: 19096787; PMCID: PMC3595129.
    176. Yang B, Zhao D, Verkman A. Hsp90 inhibitor partially corrects nephrogenic diabetes insipidus in a conditional knock-in mouse model of aquaporin-2 mutation. FASEB J. 2009 Feb; 23(2):503-12. PMID: 18854434; PMCID: PMC2630791.
    177. Tradtrantip L, Yangthara B, Padmawar P, Morrison C, Verkman A. Thiophenecarboxylate suppressor of cyclic nucleotides discovered in a small-molecule screen blocks toxin-induced intestinal fluid secretion. Mol Pharmacol. 2009 Jan; 75(1):134-42. PMID: 18824527; PMCID: PMC2685055.
    178. Yu GJ, Yoo CL, Yang B, Lodewyk MW, Meng L, El-Idreesy TT, Fettinger JC, Tantillo DJ, Verkman A, Kurth MJ. Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy. J Med Chem. 2008 Oct 9; 51(19):6044-54. PMID: 18788728; PMCID: PMC3167067.
    179. Zhang H, Verkman A. Evidence against involvement of aquaporin-4 in cell-cell adhesion. J Mol Biol. 2008 Oct 24; 382(5):1136-43. PMID: 18708067; PMCID: PMC3319413.
    180. Sonawane ND, Verkman A. Thiazolidinone CFTR inhibitors with improved water solubility identified by structure-activity analysis. Bioorg Med Chem. 2008 Sep 1; 16(17):8187-95. PMID: 18691893; PMCID: PMC2577561.
    181. Sonawane ND, Zhao D, Zegarra-Moran O, Galietta LJ, Verkman A. Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides. Chem Biol. 2008 Jul 21; 15(7):718-28. PMID: 18635008; PMCID: PMC3322358.
    182. Haggie PM, Verkman A. Monomeric CFTR in plasma membranes in live cells revealed by single molecule fluorescence imaging. J Biol Chem. 2008 Aug 29; 283(35):23510-3. PMID: 18617526; PMCID: PMC2527093.
    183. Caci E, Caputo A, Hinzpeter A, Arous N, Fanen P, Sonawane N, Verkman A, Ravazzolo R, Zegarra-Moran O, Galietta LJ. Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis. Biochem J. 2008 Jul 1; 413(1):135-42. PMID: 18366345.
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    184. Hara-Chikuma M, Verkman A. Roles of aquaporin-3 in the epidermis. J Invest Dermatol. 2008 Sep; 128(9):2145-51. PMID: 18548108.
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    185. Yang B, Zhang H, Verkman A. Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides. Bioorg Med Chem. 2008 Aug 1; 16(15):7489-93. PMID: 18572411; PMCID: PMC3325054.
    186. Namkung W, Padmawar P, Mills AD, Verkman A. Cell-based fluorescence screen for K+ channels and transporters using an extracellular triazacryptand-based K+ sensor. J Am Chem Soc. 2008 Jun 25; 130(25):7794-5. PMID: 18512924; PMCID: PMC2692188.
    187. Lu DC, Zhang H, Zador Z, Verkman A. Impaired olfaction in mice lacking aquaporin-4 water channels. FASEB J. 2008 Sep; 22(9):3216-23. PMID: 18511552; PMCID: PMC2518258.
    188. Verkman A. From the farm to the lab: the pig as a new model of cystic fibrosis lung disease. Am J Physiol Lung Cell Mol Physiol. 2008 Aug; 295(2):L238-9. PMID: 18502814.
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    189. Verkman A, Ruiz-Ederra J, Levin MH. Functions of aquaporins in the eye. Prog Retin Eye Res. 2008 Jul; 27(4):420-33. PMID: 18501660; PMCID: PMC3319433.
    190. Crane JM, Van Hoek AN, Skach WR, Verkman A. Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle tracking. Mol Biol Cell. 2008 Aug; 19(8):3369-78. PMID: 18495865; PMCID: PMC2488293.
    191. Verkman A. Mammalian aquaporins: diverse physiological roles and potential clinical significance. Expert Rev Mol Med. 2008; 10:e13. PMID: 18482462; PMCID: PMC3601943.
    192. Jin S, Zador Z, Verkman A. Random-walk model of diffusion in three dimensions in brain extracellular space: comparison with microfiberoptic photobleaching measurements. Biophys J. 2008 Aug; 95(4):1785-94. PMID: 18469079; PMCID: PMC2483768.
    193. Verkman A. Dissecting the roles of aquaporins in renal pathophysiology using transgenic mice. Semin Nephrol. 2008 May; 28(3):217-26. PMID: 18519083; PMCID: PMC2692584.
    194. Yang B, Sonawane ND, Zhao D, Somlo S, Verkman A. Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease. J Am Soc Nephrol. 2008 Jul; 19(7):1300-10. PMID: 18385427; PMCID: PMC2440296.
    195. Yang B, Zador Z, Verkman A. Glial cell aquaporin-4 overexpression in transgenic mice accelerates cytotoxic brain swelling. J Biol Chem. 2008 May 30; 283(22):15280-6. PMID: 18375385; PMCID: PMC2397463.
    196. Yoo CL, Yu GJ, Yang B, Robins LI, Verkman A, Kurth MJ. 4'-Methyl-4,5'-bithiazole-based correctors of defective delta F508-CFTR cellular processing. Bioorg Med Chem Lett. 2008 Apr 15; 18(8):2610-4. PMID: 18394886; PMCID: PMC3166558.
    197. Verkman A, Hara-Chikuma M, Papadopoulos MC. Aquaporins--new players in cancer biology. J Mol Med (Berl). 2008 May; 86(5):523-9. PMID: 18311471; PMCID: PMC3590015.
    198. Verkman A. A cautionary note on cosmetics containing ingredients that increase aquaporin-3 expression. Exp Dermatol. 2008 Oct; 17(10):871-2. PMID: 18312385.
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    199. Sonawane ND, Zegarra-Moran O, Namkung W, Galietta LJ, Verkman A. Alpha-aminoazaheterocyclic-methylglyoxal adducts do not inhibit cystic fibrosis transmembrane conductance regulator chloride channel activity. J Pharmacol Exp Ther. 2008 May; 325(2):529-35. PMID: 18272811.
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    200. Saadoun S, Bell BA, Verkman A, Papadopoulos MC. Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice. Brain. 2008 Apr; 131(Pt 4):1087-98. PMID: 18267965.
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    201. Verkman A, Galietta LJ. Chloride channels as drug targets. Nat Rev Drug Discov. 2009 Feb; 8(2):153-71. PMID: 19153558; PMCID: PMC3601949.
    202. Papadopoulos MC, Verkman A. Potential utility of aquaporin modulators for therapy of brain disorders. Prog Brain Res. 2008; 170:589-601. PMID: 18655912; PMCID: PMC3601944.
    203. Dix JA, Verkman A. Crowding effects on diffusion in solutions and cells. Annu Rev Biophys. 2008; 37:247-63. PMID: 18573081.
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    204. De La Fuente R, Namkung W, Mills A, Verkman A. Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel. Mol Pharmacol. 2008 Mar; 73(3):758-68. PMID: 18083779.
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    205. Papadopoulos MC, Saadoun S, Verkman A. Aquaporins and cell migration. Pflugers Arch. 2008 Jul; 456(4):693-700. PMID: 17968585; PMCID: PMC3595095.
    206. Hara-Chikuma M, Verkman A. Aquaporin-3 facilitates epidermal cell migration and proliferation during wound healing. J Mol Med (Berl). 2008 Feb; 86(2):221-31. PMID: 17968524.
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    207. Hara-Chikuma M, Verkman A. Prevention of skin tumorigenesis and impairment of epidermal cell proliferation by targeted aquaporin-3 gene disruption. Mol Cell Biol. 2008 Jan; 28(1):326-32. PMID: 17967887; PMCID: PMC2223314.
    208. Zador Z, Magzoub M, Jin S, Manley GT, Papadopoulos MC, Verkman A. Microfiberoptic fluorescence photobleaching reveals size-dependent macromolecule diffusion in extracellular space deep in brain. FASEB J. 2008 Mar; 22(3):870-9. PMID: 17965267.
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    209. Ruiz-Ederra J, Verkman A. Aquaporin-1 independent microvessel proliferation in a neonatal mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4802-10. PMID: 17898307.
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    210. Crane JM, Verkman A. Long-range nonanomalous diffusion of quantum dot-labeled aquaporin-1 water channels in the cell plasma membrane. Biophys J. 2008 Jan 15; 94(2):702-13. PMID: 17890385; PMCID: PMC2157255.
    211. Magzoub M, Jin S, Verkman A. Enhanced macromolecule diffusion deep in tumors after enzymatic digestion of extracellular matrix collagen and its associated proteoglycan decorin. FASEB J. 2008 Jan; 22(1):276-84. PMID: 17761521.
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    212. Haggie PM, Verkman A. Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages. J Biol Chem. 2007 Oct 26; 282(43):31422-8. PMID: 17724021.
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    213. Zhang H, Verkman A. Aquaporin-4 independent Kir4.1 K+ channel function in brain glial cells. Mol Cell Neurosci. 2008 Jan; 37(1):1-10. PMID: 17869537; PMCID: PMC2904300.
    214. Thiagarajah JR, Zhao D, Verkman A. Impaired enterocyte proliferation in aquaporin-3 deficiency in mouse models of colitis. Gut. 2007 Nov; 56(11):1529-35. PMID: 17573386; PMCID: PMC2095633.
    215. Ruiz-Ederra J, Zhang H, Verkman A. Evidence against functional interaction between aquaporin-4 water channels and Kir4.1 potassium channels in retinal Müller cells. J Biol Chem. 2007 Jul 27; 282(30):21866-72. PMID: 17525153.
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    216. Jin S, Haggie PM, Verkman A. Single-particle tracking of membrane protein diffusion in a potential: simulation, detection, and application to confined diffusion of CFTR Cl- channels. Biophys J. 2007 Aug 1; 93(3):1079-88. PMID: 17483157; PMCID: PMC1913154.
    217. Yangthara B, Mills A, Chatsudthipong V, Tradtrantip L, Verkman A. Small-molecule vasopressin-2 receptor antagonist identified by a g-protein coupled receptor "pathway" screen. Mol Pharmacol. 2007 Jul; 72(1):86-94. PMID: 17435162.
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    218. Jin S, Verkman A. Single particle tracking of complex diffusion in membranes: simulation and detection of barrier, raft, and interaction phenomena. J Phys Chem B. 2007 Apr 12; 111(14):3625-32. PMID: 17388520.
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    219. Papadopoulos MC, Verkman A. Aquaporin-4 and brain edema. Pediatr Nephrol. 2007 Jun; 22(6):778-84. PMID: 17347837.
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    220. Verkman A. Role of aquaporins in lung liquid physiology. Respir Physiol Neurobiol. 2007 Dec 15; 159(3):324-30. PMID: 17369110; PMCID: PMC3315286.
    221. Sonawane ND, Zhao D, Zegarra-Moran O, Galietta LJ, Verkman A. Lectin conjugates as potent, nonabsorbable CFTR inhibitors for reducing intestinal fluid secretion in cholera. Gastroenterology. 2007 Apr; 132(4):1234-44. PMID: 17408659.
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    222. Levin MH, de la Fuente R, Verkman A. Urearetics: a small molecule screen yields nanomolar potency inhibitors of urea transporter UT-B. FASEB J. 2007 Feb; 21(2):551-63. PMID: 17202246.
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    223. Auguste KI, Jin S, Uchida K, Yan D, Manley GT, Papadopoulos MC, Verkman A. Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury. FASEB J. 2007 Jan; 21(1):108-16. PMID: 17135365.
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    224. Yang B, Kim JK, Verkman A. Comparative efficacy of HgCl2 with candidate aquaporin-1 inhibitors DMSO, gold, TEA+ and acetazolamide. FEBS Lett. 2006 Dec 11; 580(28-29):6679-84. PMID: 17126329; PMCID: PMC3582400.
    225. Magzoub M, Padmawar P, Dix JA, Verkman A. Millisecond association kinetics of K+ with triazacryptand-based K+ indicators measured by fluorescence correlation spectroscopy. J Phys Chem B. 2006 Oct 26; 110(42):21216-21. PMID: 17048948.
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    226. Levin MH, Verkman A. Aquaporin-3-dependent cell migration and proliferation during corneal re-epithelialization. Invest Ophthalmol Vis Sci. 2006 Oct; 47(10):4365-72. PMID: 17003427.
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    227. Haggie PM, Kim JK, Lukacs GL, Verkman A. Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions. Mol Biol Cell. 2006 Dec; 17(12):4937-45. PMID: 16987954; PMCID: PMC1679663.
    228. De La Fuente R, Sonawane ND, Arumainayagam D, Verkman A. Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening. Br J Pharmacol. 2006 Nov; 149(5):551-9. PMID: 16981005; PMCID: PMC2014677.
    229. Ruiz-Ederra J, Verkman A. Accelerated cataract formation and reduced lens epithelial water permeability in aquaporin-1-deficient mice. Invest Ophthalmol Vis Sci. 2006 Sep; 47(9):3960-7. PMID: 16936111.
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    230. Perez A, Issler AC, Cotton CU, Kelley TJ, Verkman A, Davis PB. CFTR inhibition mimics the cystic fibrosis inflammatory profile. Am J Physiol Lung Cell Mol Physiol. 2007 Feb; 292(2):L383-95. PMID: 16920886.
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    231. Levin MH, Verkman A. Aquaporins and CFTR in ocular epithelial fluid transport. J Membr Biol. 2006 Mar; 210(2):105-15. PMID: 16868675.
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    232. Levin MH, Sullivan S, Nielson D, Yang B, Finkbeiner WE, Verkman A. Hypertonic saline therapy in cystic fibrosis: Evidence against the proposed mechanism involving aquaporins. J Biol Chem. 2006 Sep 1; 281(35):25803-12. PMID: 16829520.
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    233. Hu J, Verkman A. Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. FASEB J. 2006 Sep; 20(11):1892-4. PMID: 16818469.
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    234. Hara-Chikuma M, Verkman A. Physiological roles of glycerol-transporting aquaporins: the aquaglyceroporins. Cell Mol Life Sci. 2006 Jun; 63(12):1386-92. PMID: 16715408.
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    235. Ni J, Verbavatz JM, Rippe A, Boisdé I, Moulin P, Rippe B, Verkman A, Devuyst O. Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis. Kidney Int. 2006 May; 69(9):1518-25. PMID: 16508653.
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    236. Verkman A. Roles of aquaporins in kidney revealed by transgenic mice. Semin Nephrol. 2006 May; 26(3):200-8. PMID: 16713493.
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    237. Yang B, Zhao D, Verkman A. Evidence against functionally significant aquaporin expression in mitochondria. J Biol Chem. 2006 Jun 16; 281(24):16202-6. PMID: 16624821.
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    238. Yang B, Zhao D, Solenov E, Verkman A. Evidence from knockout mice against physiologically significant aquaporin 8-facilitated ammonia transport. Am J Physiol Cell Physiol. 2006 Sep; 291(3):C417-23. PMID: 16624991.
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    239. Binder DK, Yao X, Zador Z, Sick TJ, Verkman A, Manley GT. Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia. 2006 Apr 15; 53(6):631-6. PMID: 16470808.
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    240. Verkman A. Aquaporins in endothelia. Kidney Int. 2006 Apr; 69(7):1120-3. PMID: 16508658.
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    241. Thiagarajah JR, Kim JK, Magzoub M, Verkman A. Slowed diffusion in tumors revealed by microfiberoptic epifluorescence photobleaching. Nat Methods. 2006 Apr; 3(4):275-80. PMID: 16554832.
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    242. Butler TL, Au CG, Yang B, Egan JR, Tan YM, Hardeman EC, North KN, Verkman A, Winlaw DS. Cardiac aquaporin expression in humans, rats, and mice. Am J Physiol Heart Circ Physiol. 2006 Aug; 291(2):H705-13. PMID: 16582023.
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    243. Ripoche P, Goossens D, Devuyst O, Gane P, Colin Y, Verkman A, Cartron JP. Role of RhAG and AQP1 in NH3 and CO2 gas transport in red cell ghosts: a stopped-flow analysis. Transfus Clin Biol. 2006 Mar-Apr; 13(1-2):117-22. PMID: 16574458.
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    244. Bloch O, Auguste KI, Manley GT, Verkman A. Accelerated progression of kaolin-induced hydrocephalus in aquaporin-4-deficient mice. J Cereb Blood Flow Metab. 2006 Dec; 26(12):1527-37. PMID: 16552421.
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    245. Verkman A, Binder DK, Bloch O, Auguste K, Papadopoulos MC. Three distinct roles of aquaporin-4 in brain function revealed by knockout mice. Biochim Biophys Acta. 2006 Aug; 1758(8):1085-93. PMID: 16564496.
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    246. Dix JA, Hom EF, Verkman A. Fluorescence correlation spectroscopy simulations of photophysical phenomena and molecular interactions: a molecular dynamics/monte carlo approach. J Phys Chem B. 2006 Feb 2; 110(4):1896-906. PMID: 16471761; PMCID: PMC3129548.
    247. Oshio K, Watanabe H, Yan D, Verkman A, Manley GT. Impaired pain sensation in mice lacking Aquaporin-1 water channels. Biochem Biophys Res Commun. 2006 Mar 24; 341(4):1022-8. PMID: 16476579.
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    248. Yang B, Zhao D, Qian L, Verkman A. Mouse model of inducible nephrogenic diabetes insipidus produced by floxed aquaporin-2 gene deletion. Am J Physiol Renal Physiol. 2006 Aug; 291(2):F465-72. PMID: 16434568.
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    249. Binder DK, Yao X, Verkman A, Manley GT. Increased seizure duration in mice lacking aquaporin-4 water channels. Acta Neurochir Suppl. 2006; 96:389-92. PMID: 16671491.
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    250. Levin MH, Kim JK, Hu J, Verkman A. Potential difference measurements of ocular surface Na+ absorption analyzed using an electrokinetic model. Invest Ophthalmol Vis Sci. 2006 Jan; 47(1):306-16. PMID: 16384978.
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    251. Verkman A, Lukacs GL, Galietta LJ. CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis. Curr Pharm Des. 2006; 12(18):2235-47. PMID: 16787252.
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    252. Hara-Chikuma M, Verkman A. Aquaporin-1 facilitates epithelial cell migration in kidney proximal tubule. J Am Soc Nephrol. 2006 Jan; 17(1):39-45. PMID: 16319186.
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    253. Sonawane ND, Hu J, Muanprasat C, Verkman A. Luminally active, nonabsorbable CFTR inhibitors as potential therapy to reduce intestinal fluid loss in cholera. FASEB J. 2006 Jan; 20(1):130-2. PMID: 16317066.
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    254. Ruiz-Ederra J, Verkman A. Mouse model of sustained elevation in intraocular pressure produced by episcleral vein occlusion. Exp Eye Res. 2006 May; 82(5):879-84. PMID: 16310189.
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    255. Saadoun S, Papadopoulos MC, Watanabe H, Yan D, Manley GT, Verkman A. Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. J Cell Sci. 2005 Dec 15; 118(Pt 24):5691-8. PMID: 16303850.
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    256. Suen YF, Robins L, Yang B, Verkman A, Nantz MH, Kurth MJ. Sulfamoyl-4-oxoquinoline-3-carboxamides: novel potentiators of defective DeltaF508-cystic fibrosis transmembrane conductance regulator chloride channel gating. Bioorg Med Chem Lett. 2006 Feb; 16(3):537-40. PMID: 16288863.
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    257. Padmawar P, Yao X, Bloch O, Manley GT, Verkman A. K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. Nat Methods. 2005 Nov; 2(11):825-7. PMID: 16278651.
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    258. Song Y, Salinas D, Nielson DW, Verkman A. Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. Am J Physiol Cell Physiol. 2006 Mar; 290(3):C741-9. PMID: 16207791.
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    259. Bloch O, Papadopoulos MC, Manley GT, Verkman A. Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess. J Neurochem. 2005 Oct; 95(1):254-62. PMID: 16181429.
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    260. Kim SW, Gresz V, Rojek A, Wang W, Verkman A, Frøkiaer J, Nielsen S. Decreased expression of AQP2 and AQP4 water channels and Na,K-ATPase in kidney collecting duct in AQP3 null mice. Biol Cell. 2005 Oct; 97(10):765-78. PMID: 15898956.
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    261. Papadopoulos MC, Kim JK, Verkman A. Extracellular space diffusion in central nervous system: anisotropic diffusion measured by elliptical surface photobleaching. Biophys J. 2005 Nov; 89(5):3660-8. PMID: 16143636; PMCID: PMC1366858.
    262. Fang X, Song Y, Hirsch J, Galietta LJ, Pedemonte N, Zemans RL, Dolganov G, Verkman A, Matthay MA. Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L242-9. PMID: 16143588.
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    263. Morishita Y, Matsuzaki T, Hara-chikuma M, Andoo A, Shimono M, Matsuki A, Kobayashi K, Ikeda M, Yamamoto T, Verkman A, Kusano E, Ookawara S, Takata K, Sasaki S, Ishibashi K. Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. Mol Cell Biol. 2005 Sep; 25(17):7770-9. PMID: 16107722; PMCID: PMC1190286.
    264. Pedemonte N, Lukacs GL, Du K, Caci E, Zegarra-Moran O, Galietta LJ, Verkman A. Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening. J Clin Invest. 2005 Sep; 115(9):2564-71. PMID: 16127463; PMCID: PMC1190372.
    265. Lennon VA, Kryzer TJ, Pittock SJ, Verkman A, Hinson SR. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med. 2005 Aug 15; 202(4):473-7. PMID: 16087714; PMCID: PMC2212860.
    266. Verkman A. More than just water channels: unexpected cellular roles of aquaporins. J Cell Sci. 2005 Aug 1; 118(Pt 15):3225-32. PMID: 16079275.
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    267. Sohara E, Rai T, Miyazaki J, Verkman A, Sasaki S, Uchida S. Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice. Am J Physiol Renal Physiol. 2005 Dec; 289(6):F1195-200. PMID: 15998844.
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    268. Hara-Chikuma M, Verkman A. Aquaporin-3 functions as a glycerol transporter in mammalian skin. Biol Cell. 2005 Jul; 97(7):479-86. PMID: 15966863.
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    269. Schulz BL, Sloane AJ, Robinson LJ, Sebastian LT, Glanville AR, Song Y, Verkman A, Harry JL, Packer NH, Karlsson NG. Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions. Biochem J. 2005 May 1; 387(Pt 3):911-9. PMID: 15563276; PMCID: PMC1135025.
    270. Hara-Chikuma M, Wang Y, Guggino SE, Guggino WB, Verkman A. Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Biochem Biophys Res Commun. 2005 Apr 15; 329(3):941-6. PMID: 15752747.
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    271. Thiagarajah JR, Papadopoulos MC, Verkman A. Noninvasive early detection of brain edema in mice by near-infrared light scattering. J Neurosci Res. 2005 Apr 15; 80(2):293-9. PMID: 15765520.
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    272. Saadoun S, Papadopoulos MC, Hara-Chikuma M, Verkman A. Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature. 2005 Apr 7; 434(7034):786-92. PMID: 15815633.
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    273. Lechardeur D, Verkman A, Lukacs GL. Intracellular routing of plasmid DNA during non-viral gene transfer. Adv Drug Deliv Rev. 2005 Apr 5; 57(5):755-67. PMID: 15757759.
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    274. Levin MH, Verkman A. CFTR-regulated chloride transport at the ocular surface in living mice measured by potential differences. Invest Ophthalmol Vis Sci. 2005 Apr; 46(4):1428-34. PMID: 15790911.
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    275. Thiagarajah JR, Verkman A. New drug targets for cholera therapy. Trends Pharmacol Sci. 2005 Apr; 26(4):172-5. PMID: 15808339.
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    276. Hara-Chikuma M, Sohara E, Rai T, Ikawa M, Okabe M, Sasaki S, Uchida S, Verkman A. Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation. J Biol Chem. 2005 Apr 22; 280(16):15493-6. PMID: 15746100.
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    277. Pedemonte N, Sonawane ND, Taddei A, Hu J, Zegarra-Moran O, Suen YF, Robins LI, Dicus CW, Willenbring D, Nantz MH, Kurth MJ, Galietta LJ, Verkman A. Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Mol Pharmacol. 2005 May; 67(5):1797-807. PMID: 15722457.
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    278. Papadopoulos MC, Verkman A. Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. J Biol Chem. 2005 Apr 8; 280(14):13906-12. PMID: 15695511.
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    279. Yang B, Song Y, Zhao D, Verkman A. Phenotype analysis of aquaporin-8 null mice. Am J Physiol Cell Physiol. 2005 May; 288(5):C1161-70. PMID: 15647389.
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    280. Dauty E, Verkman A. Actin cytoskeleton as the principal determinant of size-dependent DNA mobility in cytoplasm: a new barrier for non-viral gene delivery. J Biol Chem. 2005 Mar 4; 280(9):7823-8. PMID: 15632160.
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    281. Sonawane ND, Muanprasat C, Nagatani R, Song Y, Verkman A. In vivo pharmacology and antidiarrheal efficacy of a thiazolidinone CFTR inhibitor in rodents. J Pharm Sci. 2005 Jan; 94(1):134-43. PMID: 15761937.
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    282. Verkman A. Novel roles of aquaporins revealed by phenotype analysis of knockout mice. Rev Physiol Biochem Pharmacol. 2005; 155:31-55. PMID: 16091927.
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    283. Papadopoulos MC, Binder DK, Verkman A. Enhanced macromolecular diffusion in brain extracellular space in mouse models of vasogenic edema measured by cortical surface photobleaching. FASEB J. 2005 Mar; 19(3):425-7. PMID: 15596484.
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    284. Salinas D, Haggie PM, Thiagarajah JR, Song Y, Rosbe K, Finkbeiner WE, Nielson DW, Verkman A. Submucosal gland dysfunction as a primary defect in cystic fibrosis. FASEB J. 2005 Mar; 19(3):431-3. PMID: 15596485.
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    285. Levin MH, Verkman A. Aquaporin-dependent water permeation at the mouse ocular surface: in vivo microfluorimetric measurements in cornea and conjunctiva. Invest Ophthalmol Vis Sci. 2004 Dec; 45(12):4423-32. PMID: 15557451.
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    286. Da T, Verkman A. Aquaporin-4 gene disruption in mice protects against impaired retinal function and cell death after ischemia. Invest Ophthalmol Vis Sci. 2004 Dec; 45(12):4477-83. PMID: 15557457.
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    287. Oshio K, Watanabe H, Song Y, Verkman A, Manley GT. Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1. FASEB J. 2005 Jan; 19(1):76-8. PMID: 15533949.
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    288. Hara-Chikuma M, Yang B, Sonawane ND, Sasaki S, Uchida S, Verkman A. ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation. J Biol Chem. 2005 Jan 14; 280(2):1241-7. PMID: 15504734.
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    289. Binder DK, Papadopoulos MC, Haggie PM, Verkman A. In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching. J Neurosci. 2004 Sep 15; 24(37):8049-56. PMID: 15371505.
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    290. Dauty E, Verkman A. Molecular crowding reduces to a similar extent the diffusion of small solutes and macromolecules: measurement by fluorescence correlation spectroscopy. J Mol Recognit. 2004 Sep-Oct; 17(5):441-7. PMID: 15362103.
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    291. Verkman A. Drug discovery and epithelial physiology. Curr Opin Nephrol Hypertens. 2004 Sep; 13(5):563-8. PMID: 15300164.
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    292. Muanprasat C, Sonawane ND, Salinas D, Taddei A, Galietta LJ, Verkman A. Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. J Gen Physiol. 2004 Aug; 124(2):125-37. PMID: 15277574; PMCID: PMC2229623.
    293. Song Y, Sonawane ND, Salinas D, Qian L, Pedemonte N, Galietta LJ, Verkman A. Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models. J Biol Chem. 2004 Sep 24; 279(39):40629-33. PMID: 15280357.
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    294. Salinas DB, Pedemonte N, Muanprasat C, Finkbeiner WF, Nielson DW, Verkman A. CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor. Am J Physiol Lung Cell Mol Physiol. 2004 Nov; 287(5):L936-43. PMID: 15246976.
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    295. Papadopoulos MC, Manley GT, Krishna S, Verkman A. Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J. 2004 Aug; 18(11):1291-3. PMID: 15208268.
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    296. Kuang K, Yiming M, Wen Q, Li Y, Ma L, Iserovich P, Verkman A, Fischbarg J. Fluid transport across cultured layers of corneal endothelium from aquaporin-1 null mice. Exp Eye Res. 2004 Apr; 78(4):791-8. PMID: 15037113.
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    297. Thiagarajah JR, Song Y, Haggie PM, Verkman A. A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways. FASEB J. 2004 May; 18(7):875-7. PMID: 15001557.
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    298. Verkman A. Drug discovery in academia. Am J Physiol Cell Physiol. 2004 Mar; 286(3):C465-74. PMID: 14761879.
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    299. Binder DK, Oshio K, Ma T, Verkman A, Manley GT. Increased seizure threshold in mice lacking aquaporin-4 water channels. Neuroreport. 2004 Feb 9; 15(2):259-62. PMID: 15076748.
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    300. Thiagarajah JR, Broadbent T, Hsieh E, Verkman A. Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor. Gastroenterology. 2004 Feb; 126(2):511-9. PMID: 14762788.
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    301. Taddei A, Folli C, Zegarra-Moran O, Fanen P, Verkman A, Galietta LJ. Altered channel gating mechanism for CFTR inhibition by a high-affinity thiazolidinone blocker. FEBS Lett. 2004 Jan 30; 558(1-3):52-6. PMID: 14759515.
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    302. Oshio K, Binder DK, Yang B, Schecter S, Verkman A, Manley GT. Expression of aquaporin water channels in mouse spinal cord. Neuroscience. 2004; 127(3):685-93. PMID: 15283967.
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    303. Manley GT, Binder DK, Papadopoulos MC, Verkman A. New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Neuroscience. 2004; 129(4):983-91. PMID: 15561413.
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    304. Papadopoulos MC, Saadoun S, Binder DK, Manley GT, Krishna S, Verkman A. Molecular mechanisms of brain tumor edema. Neuroscience. 2004; 129(4):1011-20. PMID: 15561416.
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    305. Thiagarajah JR, Verkman A. CFTR pharmacology and its role in intestinal fluid secretion. Curr Opin Pharmacol. 2003 Dec; 3(6):594-9. PMID: 14644010.
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    306. Haggie PM, Stanton BA, Verkman A. Increased diffusional mobility of CFTR at the plasma membrane after deletion of its C-terminal PDZ binding motif. J Biol Chem. 2004 Feb 13; 279(7):5494-500. PMID: 14660592.
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    307. Solenov E, Watanabe H, Manley GT, Verkman A. Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method. Am J Physiol Cell Physiol. 2004 Feb; 286(2):C426-32. PMID: 14576087.
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    308. Song Y, Thiagarajah J, Verkman A. Sodium and chloride concentrations, pH, and depth of airway surface liquid in distal airways. J Gen Physiol. 2003 Nov; 122(5):511-9. PMID: 14557401; PMCID: PMC2229580.
    309. Springsteel MF, Galietta LJ, Ma T, By K, Berger GO, Yang H, Dicus CW, Choung W, Quan C, Shelat AA, Guy RK, Verkman A, Kurth MJ, Nantz MH. Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain. Bioorg Med Chem. 2003 Sep 1; 11(18):4113-20. PMID: 12927873.
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    310. Sonawane ND, Szoka FC, Verkman A. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem. 2003 Nov 7; 278(45):44826-31. PMID: 12944394.
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    311. Sammelson RE, Ma T, Galietta LJ, Verkman A, Kurth MJ. 3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: synthesis and evaluation as CFTR activators. Bioorg Med Chem Lett. 2003 Aug 4; 13(15):2509-12. PMID: 12852954.
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    312. Yang H, Shelat AA, Guy RK, Gopinath VS, Ma T, Du K, Lukacs GL, Taddei A, Folli C, Pedemonte N, Galietta LJ, Verkman A. Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating. J Biol Chem. 2003 Sep 12; 278(37):35079-85. PMID: 12832418.
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    313. Hara M, Verkman A. Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice. Proc Natl Acad Sci U S A. 2003 Jun 10; 100(12):7360-5. PMID: 12771381; PMCID: PMC165880.
    314. Kim YH, Kim J, Verkman A, Madsen KM. Increased expression of H+-ATPase in inner medullary collecting duct of aquaporin-1-deficient mice. Am J Physiol Renal Physiol. 2003 Sep; 285(3):F550-7. PMID: 12759225.
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    315. Sonawane ND, Verkman A. Determinants of [Cl-] in recycling and late endosomes and Golgi complex measured using fluorescent ligands. J Cell Biol. 2003 Mar 31; 160(7):1129-38. PMID: 12668661; PMCID: PMC2172765.
    316. Caci E, Folli C, Zegarra-Moran O, Ma T, Springsteel MF, Sammelson RE, Nantz MH, Kurth MJ, Verkman A, Galietta LJ. CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L180-8. PMID: 12651632.
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    317. Verkman A. Role of aquaporin water channels in eye function. Exp Eye Res. 2003 Feb; 76(2):137-43. PMID: 12565800.
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    318. Verkman A. Diffusion in cells measured by fluorescence recovery after photobleaching. Methods Enzymol. 2003; 360:635-48. PMID: 12622172.
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    319. Verkman A, Song Y, Thiagarajah JR. Role of airway surface liquid and submucosal glands in cystic fibrosis lung disease. Am J Physiol Cell Physiol. 2003 Jan; 284(1):C2-15. PMID: 12475759.
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    320. Oshio K, Binder DK, Bollen A, Verkman A, Berger MS, Manley GT. Aquaporin-1 expression in human glial tumors suggests a potential novel therapeutic target for tumor-associated edema. Acta Neurochir Suppl. 2003; 86:499-502. PMID: 14753494.
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    321. Oshio K, Song Y, Verkman A, Manley GT. Aquaporin-1 deletion reduces osmotic water permeability and cerebrospinal fluid production. Acta Neurochir Suppl. 2003; 86:525-8. PMID: 14753499.
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    322. Ma T, Thiagarajah JR, Yang H, Sonawane ND, Folli C, Galietta LJ, Verkman A. Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest. 2002 Dec; 110(11):1651-8. PMID: 12464670; PMCID: PMC151633.
    323. Borok Z, Verkman A. Lung edema clearance: 20 years of progress: invited review: role of aquaporin water channels in fluid transport in lung and airways. J Appl Physiol (1985). 2002 Dec; 93(6):2199-206. PMID: 12433939.
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    324. Mann SE, Ricke EA, Yang BA, Verkman A, Taylor RN. Expression and localization of aquaporin 1 and 3 in human fetal membranes. Am J Obstet Gynecol. 2002 Oct; 187(4):902-7. PMID: 12388974.
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    325. Hara M, Ma T, Verkman A. Selectively reduced glycerol in skin of aquaporin-3-deficient mice may account for impaired skin hydration, elasticity, and barrier recovery. J Biol Chem. 2002 Nov 29; 277(48):46616-21. PMID: 12270942.
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    326. Mennone A, Verkman A, Boyer JL. Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3):G739-46. PMID: 12181190.
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    327. Papadopoulos MC, Krishna S, Verkman A. Aquaporin water channels and brain edema. Mt Sinai J Med. 2002 Sep; 69(4):242-8. PMID: 12357265.
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    328. Jiang J, Song Y, Bai C, Koller BH, Matthay MA, Verkman A. Pleural surface fluorescence measurement of Na+ and Cl- transport across the air space-capillary barrier. J Appl Physiol (1985). 2003 Jan; 94(1):343-52. PMID: 12391048.
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    329. Haggie PM, Verkman A. Diffusion of tricarboxylic acid cycle enzymes in the mitochondrial matrix in vivo. Evidence for restricted mobility of a multienzyme complex. J Biol Chem. 2002 Oct 25; 277(43):40782-8. PMID: 12198136.
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    330. Ma T, Vetrivel L, Yang H, Pedemonte N, Zegarra-Moran O, Galietta LJ, Verkman A. High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening. J Biol Chem. 2002 Oct 4; 277(40):37235-41. PMID: 12161441.
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    331. Yang B, Verkman A. Analysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytes. J Biol Chem. 2002 Sep 27; 277(39):36782-6. PMID: 12133842.
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    332. Verkman A. Does aquaporin-1 pass gas? An opposing view. J Physiol. 2002 Jul 1; 542(Pt 1):31. PMID: 12096046; PMCID: PMC2290386.
    333. Hom EF, Verkman A. Analysis of coupled bimolecular reaction kinetics and diffusion by two-color fluorescence correlation spectroscopy: enhanced resolution of kinetics by resonance energy transfer. Biophys J. 2002 Jul; 83(1):533-46. PMID: 12080140; PMCID: PMC1302167.
    334. Fang X, Yang B, Matthay MA, Verkman A. Evidence against aquaporin-1-dependent CO2 permeability in lung and kidney. J Physiol. 2002 Jul 1; 542(Pt 1):63-9. PMID: 12096051; PMCID: PMC2290384.
    335. Verkman A. Aquaporin water channels and endothelial cell function. J Anat. 2002 Jun; 200(6):617-27. PMID: 12162729; PMCID: PMC1570747.
    336. Zhang D, Vetrivel L, Verkman A. Aquaporin deletion in mice reduces intraocular pressure and aqueous fluid production. J Gen Physiol. 2002 Jun; 119(6):561-9. PMID: 12034763; PMCID: PMC2233864.
    337. Song Y, Sonawane N, Verkman A. Localization of aquaporin-5 in sweat glands and functional analysis using knockout mice. J Physiol. 2002 Jun 1; 541(Pt 2):561-8. PMID: 12042359; PMCID: PMC2290337.
    338. Thiagarajah JR, Verkman A. Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling. J Biol Chem. 2002 May 24; 277(21):19139-44. PMID: 11891232.
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    339. Ma T, Hara M, Sougrat R, Verbavatz JM, Verkman A. Impaired stratum corneum hydration in mice lacking epidermal water channel aquaporin-3. J Biol Chem. 2002 May 10; 277(19):17147-53. PMID: 11880378.
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    340. Haggie PM, Stanton BA, Verkman A. Diffusional mobility of the cystic fibrosis transmembrane conductance regulator mutant, delta F508-CFTR, in the endoplasmic reticulum measured by photobleaching of GFP-CFTR chimeras. J Biol Chem. 2002 May 10; 277(19):16419-25. PMID: 11877404.
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    341. Fang X, Fukuda N, Barbry P, Sartori C, Verkman A, Matthay MA. Novel role for CFTR in fluid absorption from the distal airspaces of the lung. J Gen Physiol. 2002 Feb; 119(2):199-207. PMID: 11815669; PMCID: PMC2233804.
    342. Li J, Patil RV, Verkman A. Mildly abnormal retinal function in transgenic mice without Müller cell aquaporin-4 water channels. Invest Ophthalmol Vis Sci. 2002 Feb; 43(2):573-9. PMID: 11818406.
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    343. Yang B, Bankir L, Gillespie A, Epstein CJ, Verkman A. Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B. J Biol Chem. 2002 Mar 22; 277(12):10633-7. PMID: 11792714.
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    344. Solenov EI, Vetrivel L, Oshio K, Manley GT, Verkman A. Optical measurement of swelling and water transport in spinal cord slices from aquaporin null mice. J Neurosci Methods. 2002 Jan 15; 113(1):85-90. PMID: 11741725.
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    345. Verkman A, Yang B. Aquaporin gene delivery to kidney. Kidney Int. 2002 Jan; 61(1 Suppl):S120-4. PMID: 11841625.
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    346. Verkman A. Solute and macromolecule diffusion in cellular aqueous compartments. Trends Biochem Sci. 2002 Jan; 27(1):27-33. PMID: 11796221.
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    347. Verkman A, Jayaraman S. Fluorescent indicator methods to assay functional CFTR expression in cells. Methods Mol Med. 2002; 70:187-96. PMID: 11917522.
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    348. Verkman A. Physiological importance of aquaporin water channels. Ann Med. 2002; 34(3):192-200. PMID: 12173689.
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    350. Sonawane ND, Thiagarajah JR, Verkman A. Chloride concentration in endosomes measured using a ratioable fluorescent Cl- indicator: evidence for chloride accumulation during acidification. J Biol Chem. 2002 Feb 15; 277(7):5506-13. PMID: 11741919.
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    351. Thiagarajah JR, Jayaraman S, Naftalin RJ, Verkman A. In vivo fluorescence measurement of Na(+) concentration in the pericryptal space of mouse descending colon. Am J Physiol Cell Physiol. 2001 Dec; 281(6):C1898-903. PMID: 11698248.
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    352. Zhou Q, Clarke L, Nie R, Carnes K, Lai LW, Lien YH, Verkman A, Lubahn D, Fisher JS, Katzenellenbogen BS, Hess RA. Estrogen action and male fertility: roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):14132-7. PMID: 11698654; PMCID: PMC61180.
    353. Jayaraman S, Song Y, Verkman A. Airway surface liquid pH in well-differentiated airway epithelial cell cultures and mouse trachea. Am J Physiol Cell Physiol. 2001 Nov; 281(5):C1504-11. PMID: 11600413.
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    354. Galietta LV, Jayaraman S, Verkman A. Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists. Am J Physiol Cell Physiol. 2001 Nov; 281(5):C1734-42. PMID: 11600438.
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    355. Verkman A. Applications of aquaporin inhibitors. Drug News Perspect. 2001 Sep; 14(7):412-20. PMID: 12813584.
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    356. Kim YH, Earm JH, Ma T, Verkman A, Knepper MA, Madsen KM, Kim J. Aquaporin-4 expression in adult and developing mouse and rat kidney. J Am Soc Nephrol. 2001 Sep; 12(9):1795-804. PMID: 11518772.
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    357. Song Y, Verkman A. Aquaporin-5 dependent fluid secretion in airway submucosal glands. J Biol Chem. 2001 Nov 2; 276(44):41288-92. PMID: 11514581.
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    358. Verkman A. Lung disease in cystic fibrosis: is airway surface liquid composition abnormal? Am J Physiol Lung Cell Mol Physiol. 2001 Aug; 281(2):L306-8. PMID: 11435202.
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    359. Joo NS, Krouse ME, Wu JV, Saenz Y, Jayaraman S, Verkman A, Wine JJ. HCO3- transport in relation to mucus secretion from submucosal glands. JOP. 2001 Jul; 2(4 Suppl):280-4. PMID: 11875272.
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    360. Jayaraman S, Joo NS, Reitz B, Wine JJ, Verkman A. Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na(+)] and pH but elevated viscosity. Proc Natl Acad Sci U S A. 2001 Jul 3; 98(14):8119-23. PMID: 11427704; PMCID: PMC35477.
    361. Galietta LJ, Haggie PM, Verkman A. Green fluorescent protein-based halide indicators with improved chloride and iodide affinities. FEBS Lett. 2001 Jun 22; 499(3):220-4. PMID: 11423120.
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    362. Li J, Verkman A. Impaired hearing in mice lacking aquaporin-4 water channels. J Biol Chem. 2001 Aug 17; 276(33):31233-7. PMID: 11406631.
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    363. Song Y, Jayaraman S, Yang B, Matthay MA, Verkman A. Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration. J Gen Physiol. 2001 Jun; 117(6):573-82. PMID: 11382807; PMCID: PMC2232398.
    364. Jayaraman S, Song Y, Verkman A. Airway surface liquid osmolality measured using fluorophore-encapsulated liposomes. J Gen Physiol. 2001 May; 117(5):423-30. PMID: 11331352; PMCID: PMC2233658.
    365. Levin MH, Haggie PM, Vetrivel L, Verkman A. Diffusion in the endoplasmic reticulum of an aquaporin-2 mutant causing human nephrogenic diabetes insipidus. J Biol Chem. 2001 Jun 15; 276(24):21331-6. PMID: 11297561.
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    366. Galietta LJ, Springsteel MF, Eda M, Niedzinski EJ, By K, Haddadin MJ, Kurth MJ, Nantz MH, Verkman A. Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. J Biol Chem. 2001 Jun 8; 276(23):19723-8. PMID: 11262417.
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    367. Jayaraman S, Song Y, Vetrivel L, Shankar L, Verkman A. Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH. J Clin Invest. 2001 Feb; 107(3):317-24. PMID: 11160155; PMCID: PMC199195.
    368. Yang B, Ma T, Verkman A. Erythrocyte water permeability and renal function in double knockout mice lacking aquaporin-1 and aquaporin-3. J Biol Chem. 2001 Jan 5; 276(1):624-8. PMID: 11035042.
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    369. Ma T, Jayaraman S, Wang KS, Song Y, Yang B, Li J, Bastidas JA, Verkman A. Defective dietary fat processing in transgenic mice lacking aquaporin-1 water channels. Am J Physiol Cell Physiol. 2001 Jan; 280(1):C126-34. PMID: 11121384; PMCID: PMC3491804.
    370. Song Y, Yang B, Matthay MA, Ma T, Verkman A. Role of aquaporin water channels in pleural fluid dynamics. Am J Physiol Cell Physiol. 2000 Dec; 279(6):C1744-50. PMID: 11078688.
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    371. Foster W, Helm A, Turnbull I, Gulati H, Yang B, Verkman A, Skach WR. Identification of sequence determinants that direct different intracellular folding pathways for aquaporin-1 and aquaporin-4. J Biol Chem. 2000 Nov 3; 275(44):34157-65. PMID: 10944517.
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    372. Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman A. Neonatal mortality in an aquaporin-2 knock-in mouse model of recessive nephrogenic diabetes insipidus. J Biol Chem. 2001 Jan 26; 276(4):2775-9. PMID: 11035038.
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    373. Lu Y, Turnbull IR, Bragin A, Carveth K, Verkman A, Skach WR. Reorientation of aquaporin-1 topology during maturation in the endoplasmic reticulum. Mol Biol Cell. 2000 Sep; 11(9):2973-85. PMID: 10982394; PMCID: PMC14969.
    374. Verkman A. Physiological importance of aquaporins: lessons from knockout mice. Curr Opin Nephrol Hypertens. 2000 Sep; 9(5):517-22. PMID: 10990371.
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    375. Wang KS, Ma T, Filiz F, Verkman A, Bastidas JA. Colon water transport in transgenic mice lacking aquaporin-4 water channels. Am J Physiol Gastrointest Liver Physiol. 2000 Aug; 279(2):G463-70. PMID: 10915657; PMCID: PMC3495185.
    376. Wang KS, Komar AR, Ma T, Filiz F, McLeroy J, Hoda K, Verkman A, Bastidas JA. Gastric acid secretion in aquaporin-4 knockout mice. Am J Physiol Gastrointest Liver Physiol. 2000 Aug; 279(2):G448-53. PMID: 10915655; PMCID: PMC3495182.
    377. Rao S, Verkman A. Analysis of organ physiology in transgenic mice. Am J Physiol Cell Physiol. 2000 Jul; 279(1):C1-C18. PMID: 10898711.
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    378. Wiener MC, Verkman A, Stroud RM, van Hoek AN. Mesoscopic surfactant organization and membrane protein crystallization. Protein Sci. 2000 Jul; 9(7):1407-9. PMID: 10933509; PMCID: PMC2144676.
    379. Song Y, Fukuda N, Bai C, Ma T, Matthay MA, Verkman A. Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: studies in transgenic aquaporin null mice. J Physiol. 2000 Jun 15; 525 Pt 3:771-9. PMID: 10856128; PMCID: PMC2269974.
    380. Yang B, Verbavatz JM, Song Y, Vetrivel L, Manley G, Kao WM, Ma T, Verkman A. Skeletal muscle function and water permeability in aquaporin-4 deficient mice. Am J Physiol Cell Physiol. 2000 Jun; 278(6):C1108-15. PMID: 10837338.
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    381. Vallon V, Verkman A, Schnermann J. Luminal hypotonicity in proximal tubules of aquaporin-1-knockout mice. Am J Physiol Renal Physiol. 2000 Jun; 278(6):F1030-3. PMID: 10836992.
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    382. Jayaraman S, Verkman A. Quenching mechanism of quinolinium-type chloride-sensitive fluorescent indicators. Biophys Chem. 2000 May 31; 85(1):49-57. PMID: 10885398.
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    383. Verkman A, Matthay MA, Song Y. Aquaporin water channels and lung physiology. Am J Physiol Lung Cell Mol Physiol. 2000 May; 278(5):L867-79. PMID: 10781416.
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    384. Moore M, Ma T, Yang B, Verkman A. Tear secretion by lacrimal glands in transgenic mice lacking water channels AQP1, AQP3, AQP4 and AQP5. Exp Eye Res. 2000 May; 70(5):557-62. PMID: 10870513.
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    385. Ma T, Song Y, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman A. Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4386-91. PMID: 10737773; PMCID: PMC18251.
    386. Jayaraman S, Haggie P, Wachter RM, Remington SJ, Verkman A. Mechanism and cellular applications of a green fluorescent protein-based halide sensor. J Biol Chem. 2000 Mar 3; 275(9):6047-50. PMID: 10692389.
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    387. Verkman A, Yang B, Song Y, Manley GT, Ma T. Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice. Exp Physiol. 2000 Mar; 85 Spec No:233S-241S. PMID: 10795927.
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    388. Masseguin C, Corcoran M, Carcenac C, Daunton NG, Güell A, Verkman A, Gabrion J. Altered gravity downregulates aquaporin-1 protein expression in choroid plexus. J Appl Physiol (1985). 2000 Mar; 88(3):843-50. PMID: 10710377.
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    389. Yang B, Ma T, Dong JY, Verkman A. Partial correction of the urinary concentrating defect in aquaporin-1 null mice by adenovirus-mediated gene delivery. Hum Gene Ther. 2000 Mar 1; 11(4):567-75. PMID: 10724035.
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    390. van Hoek AN, Ma T, Yang B, Verkman A, Brown D. Aquaporin-4 is expressed in basolateral membranes of proximal tubule S3 segments in mouse kidney. Am J Physiol Renal Physiol. 2000 Feb; 278(2):F310-6. PMID: 10662735.
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    391. Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, Bollen AW, Chan P, Verkman A. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med. 2000 Feb; 6(2):159-63. PMID: 10655103.
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    392. Umenishi F, Verbavatz JM, Verkman A. cAMP regulated membrane diffusion of a green fluorescent protein-aquaporin 2 chimera. Biophys J. 2000 Feb; 78(2):1024-35. PMID: 10653816; PMCID: PMC1300706.
    393. Yang B, Fukuda N, van Hoek A, Matthay MA, Ma T, Verkman A. Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J Biol Chem. 2000 Jan 28; 275(4):2686-92. PMID: 10644730.
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    394. Lukacs GL, Haggie P, Seksek O, Lechardeur D, Freedman N, Verkman A. Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem. 2000 Jan 21; 275(3):1625-9. PMID: 10636854.
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    395. Verkman A. Water permeability measurement in living cells and complex tissues. J Membr Biol. 2000 Jan 15; 173(2):73-87. PMID: 10630923.
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    396. Verkman A, Mitra AK. Structure and function of aquaporin water channels. Am J Physiol Renal Physiol. 2000 Jan; 278(1):F13-28. PMID: 10644652.
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    397. Song Y, Ma T, Matthay MA, Verkman A. Role of aquaporin-4 in airspace-to-capillary water permeability in intact mouse lung measured by a novel gravimetric method. J Gen Physiol. 2000 Jan; 115(1):17-27. PMID: 10613915; PMCID: PMC1887782.
    398. Pallone TL, Edwards A, Ma T, Silldorff EP, Verkman A. Requirement of aquaporin-1 for NaCl-driven water transport across descending vasa recta. J Clin Invest. 2000 Jan; 105(2):215-22. PMID: 10642600; PMCID: PMC382858.
    399. Ma T, Fukuda N, Song Y, Matthay MA, Verkman A. Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest. 2000 Jan; 105(1):93-100. PMID: 10619865; PMCID: PMC382590.
    400. Tamarappoo BK, Yang B, Verkman A. Misfolding of mutant aquaporin-2 water channels in nephrogenic diabetes insipidus. J Biol Chem. 1999 Dec 3; 274(49):34825-31. PMID: 10574954.
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    401. Jayaraman S, Teitler L, Skalski B, Verkman A. Long-wavelength iodide-sensitive fluorescent indicators for measurement of functional CFTR expression in cells. Am J Physiol. 1999 Nov; 277(5 Pt 1):C1008-18. PMID: 10564094.
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    402. Ma T, Song Y, Gillespie A, Carlson EJ, Epstein CJ, Verkman A. Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem. 1999 Jul 16; 274(29):20071-4. PMID: 10400615.
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    403. Ma T, Verkman A. Aquaporin water channels in gastrointestinal physiology. J Physiol. 1999 Jun 1; 517 ( Pt 2):317-26. PMID: 10332084; PMCID: PMC2269340.
    404. Verkman A. Lessons on renal physiology from transgenic mice lacking aquaporin water channels. J Am Soc Nephrol. 1999 May; 10(5):1126-35. PMID: 10232700.
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    405. Dayel MJ, Hom EF, Verkman A. Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum. Biophys J. 1999 May; 76(5):2843-51. PMID: 10233100; PMCID: PMC1300255.
    406. Mansoura MK, Biwersi J, Ashlock MA, Verkman A. Fluorescent chloride indicators to assess the efficacy of CFTR cDNA delivery. Hum Gene Ther. 1999 Apr 10; 10(6):861-75. PMID: 10223721.
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    407. Yang B, Ma T, Xu Z, Verkman A. cDNA and genomic cloning of mouse aquaporin-2: functional analysis of an orthologous mutant causing nephrogenic diabetes insipidus. Genomics. 1999 Apr 1; 57(1):79-83. PMID: 10191086.
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    408. Farinas J, Verkman A. Receptor-mediated targeting of fluorescent probes in living cells. J Biol Chem. 1999 Mar 19; 274(12):7603-6. PMID: 10075643.
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    409. Jayaraman S, Biwersi J, Verkman A. Synthesis and characterization of dual-wavelength Cl--sensitive fluorescent indicators for ratio imaging. Am J Physiol. 1999 Mar; 276(3 Pt 1):C747-57. PMID: 10070003.
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    410. Chou CL, Knepper MA, Hoek AN, Brown D, Yang B, Ma T, Verkman A. Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice. J Clin Invest. 1999 Feb; 103(4):491-6. PMID: 10021457; PMCID: PMC408109.
    411. Bai C, Fukuda N, Song Y, Ma T, Matthay MA, Verkman A. Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice. J Clin Invest. 1999 Feb; 103(4):555-61. PMID: 10021464; PMCID: PMC408096.
    412. Yang B, Folkesson HG, Yang J, Matthay MA, Ma T, Verkman A. Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice. Am J Physiol. 1999 Jan; 276(1 Pt 1):C76-81. PMID: 9886922.
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    413. Verkman A. Green fluorescent protein as a probe to study intracellular solute diffusion. Methods Enzymol. 1999; 302:250-64. PMID: 12876777.
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    414. Verkman A. Role of aquaporin water channels in kidney and lung. Am J Med Sci. 1998 Nov; 316(5):310-20. PMID: 9822113.
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    415. Gustafson CE, Levine S, Katsura T, McLaughlin M, Aleixo MD, Tamarappoo BK, Verkman A, Brown D. Vasopressin regulated trafficking of a green fluorescent protein-aquaporin 2 chimera in LLC-PK1 cells. Histochem Cell Biol. 1998 Oct; 110(4):377-86. PMID: 9792416.
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    416. Schnermann J, Chou CL, Ma T, Traynor T, Knepper MA, Verkman A. Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proc Natl Acad Sci U S A. 1998 Aug 4; 95(16):9660-4. PMID: 9689137; PMCID: PMC21395.
    417. Periasamy N, Verkman A. Analysis of fluorophore diffusion by continuous distributions of diffusion coefficients: application to photobleaching measurements of multicomponent and anomalous diffusion. Biophys J. 1998 Jul; 75(1):557-67. PMID: 9649418; PMCID: PMC1299730.
    418. Bai C, Biwersi J, Verkman A, Matthay MA. A mouse model to test the in vivo efficacy of chemical chaperones. J Pharmacol Toxicol Methods. 1998 Jul; 40(1):39-45. PMID: 9920533.
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    419. Ma T, Yang B, Matthay MA, Verkman A. Evidence against a role of mouse, rat, and two cloned human t1alpha isoforms as a water channel or a regulator of aquaporin-type water channels. Am J Respir Cell Mol Biol. 1998 Jul; 19(1):143-9. PMID: 9651190.
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    420. Umenishi F, Verkman A. Isolation and functional analysis of alternative promoters in the human aquaporin-4 water channel gene. Genomics. 1998 Jun 15; 50(3):373-7. PMID: 9676432.
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    421. Tamarappoo BK, Verkman A. Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones. J Clin Invest. 1998 May 15; 101(10):2257-67. PMID: 9593782; PMCID: PMC508814.
    422. Olveczky BP, Verkman A. Monte Carlo analysis of obstructed diffusion in three dimensions: application to molecular diffusion in organelles. Biophys J. 1998 May; 74(5):2722-30. PMID: 9591696; PMCID: PMC1299612.
    423. Yang B, Verkman A. Urea transporter UT3 functions as an efficient water channel. Direct evidence for a common water/urea pathway. J Biol Chem. 1998 Apr 17; 273(16):9369-72. PMID: 9545259.
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    424. Carter EP, Olveczky BP, Matthay MA, Verkman A. High microvascular endothelial water permeability in mouse lung measured by a pleural surface fluorescence method. Biophys J. 1998 Apr; 74(4):2121-8. PMID: 9545071; PMCID: PMC1299553.
    425. Dobbs LG, Gonzalez R, Matthay MA, Carter EP, Allen L, Verkman A. Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2991-6. PMID: 9501203; PMCID: PMC19682.
    426. Kneen M, Farinas J, Li Y, Verkman A. Green fluorescent protein as a noninvasive intracellular pH indicator. Biophys J. 1998 Mar; 74(3):1591-9. PMID: 9512054; PMCID: PMC1299504.
    427. Neville DC, Rozanas CR, Tulk BM, Townsend RR, Verkman A. Expression and characterization of the NBD1-R domain region of CFTR: evidence for subunit-subunit interactions. Biochemistry. 1998 Feb 24; 37(8):2401-9. PMID: 9485388.
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    428. Partikian A, Olveczky B, Swaminathan R, Li Y, Verkman A. Rapid diffusion of green fluorescent protein in the mitochondrial matrix. J Cell Biol. 1998 Feb 23; 140(4):821-9. PMID: 9472034; PMCID: PMC2141758.
    429. Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman A. Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J Biol Chem. 1998 Feb 20; 273(8):4296-9. PMID: 9468475.
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    430. Chou CL, Ma T, Yang B, Knepper MA, Verkman A. Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice. Am J Physiol. 1998 Feb; 274(2 Pt 1):C549-54. PMID: 9486146.
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    431. Umenishi F, Verkman A. Isolation of the human aquaporin-1 promoter and functional characterization in human erythroleukemia cell lines. Genomics. 1998 Feb 1; 47(3):341-9. PMID: 9480747.
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    432. Toriano R, Ford P, Rivarola V, Tamarappoo BK, Verkman A, Parisi M. Reconstitution of a regulated transepithelial water pathway in cells transfected with AQP2 and an AQP1/AQP2 hybrid containing the AQP2-C terminus. J Membr Biol. 1998 Jan 15; 161(2):141-9. PMID: 9435270.
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    433. Ma T, Yang B, Verkman A. Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver, and heart. Biochem Biophys Res Commun. 1997 Nov 17; 240(2):324-8. PMID: 9388476.
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    434. Olveczky BP, Periasamy N, Verkman A. Mapping fluorophore distributions in three dimensions by quantitative multiple angle-total internal reflection fluorescence microscopy. Biophys J. 1997 Nov; 73(5):2836-47. PMID: 9370477; PMCID: PMC1181185.
    435. Verbavatz JM, Ma T, Gobin R, Verkman A. Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4. J Cell Sci. 1997 Nov; 110 ( Pt 22):2855-60. PMID: 9427293.
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    436. Neville DC, Rozanas CR, Price EM, Gruis DB, Verkman A, Townsend RR. Evidence for phosphorylation of serine 753 in CFTR using a novel metal-ion affinity resin and matrix-assisted laser desorption mass spectrometry. Protein Sci. 1997 Nov; 6(11):2436-45. PMID: 9385646; PMCID: PMC2143598.
    437. Canfield MC, Tamarappoo BK, Moses AM, Verkman A, Holtzman EJ. Identification and characterization of aquaporin-2 water channel mutations causing nephrogenic diabetes insipidus with partial vasopressin response. Hum Mol Genet. 1997 Oct; 6(11):1865-71. PMID: 9302264.
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    438. Farinas J, Kneen M, Moore M, Verkman A. Plasma membrane water permeability of cultured cells and epithelia measured by light microscopy with spatial filtering. J Gen Physiol. 1997 Sep; 110(3):283-96. PMID: 9276754; PMCID: PMC2229369.
    439. Carter EP, Umenishi F, Matthay MA, Verkman A. Developmental changes in water permeability across the alveolar barrier in perinatal rabbit lung. J Clin Invest. 1997 Sep 1; 100(5):1071-8. PMID: 9276723; PMCID: PMC508281.
    440. Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman A. Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J Clin Invest. 1997 Sep 1; 100(5):957-62. PMID: 9276712; PMCID: PMC508270.
    441. Ma T, Yang B, Umenishi F, Verkman A. Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13. Genomics. 1997 Aug 1; 43(3):387-9. PMID: 9268644.
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    442. Seksek O, Biwersi J, Verkman A. Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus. J Cell Biol. 1997 Jul 14; 138(1):131-42. PMID: 9214387; PMCID: PMC2139942.
    443. Yang B, Verkman A. Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes. J Biol Chem. 1997 Jun 27; 272(26):16140-6. PMID: 9195910.
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    444. Yang B, van Hoek AN, Verkman A. Very high single channel water permeability of aquaporin-4 in baculovirus-infected insect cells and liposomes reconstituted with purified aquaporin-4. Biochemistry. 1997 Jun 17; 36(24):7625-32. PMID: 9200715.
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    445. Cheng A, van Hoek AN, Yeager M, Verkman A, Mitra AK. Three-dimensional organization of a human water channel. Nature. 1997 Jun 5; 387(6633):627-30. PMID: 9177354.
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    446. Swaminathan R, Hoang CP, Verkman A. Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion. Biophys J. 1997 Apr; 72(4):1900-7. PMID: 9083693; PMCID: PMC1184383.
    447. Verkman A, Yang B. Aquaporins and ion conductance. Science. 1997 Mar 7; 275(5305):1491; author reply 1492. PMID: 9072811.
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    448. Farinas J, Verkman A. Cell volume and plasma membrane osmotic water permeability in epithelial cell layers measured by interferometry. Biophys J. 1996 Dec; 71(6):3511-22. PMID: 8968620; PMCID: PMC1233838.
    449. Umenishi F, Carter EP, Yang B, Oliver B, Matthay MA, Verkman A. Sharp increase in rat lung water channel expression in the perinatal period. Am J Respir Cell Mol Biol. 1996 Nov; 15(5):673-9. PMID: 8918374.
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    450. Thevenin BJ, Bicknese SE, Park J, Verkman A, Shohet SB. Distance between Cys-201 in erythrocyte band 3 and the bilayer measured by single-photon radioluminescence. Biophys J. 1996 Nov; 71(5):2645-55. PMID: 8913602; PMCID: PMC1233751.
    451. Ma T, Yang B, Verkman A. cDNA cloning of a functional water channel from toad urinary bladder epithelium. Am J Physiol. 1996 Nov; 271(5 Pt 1):C1699-704. PMID: 8944654.
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    452. Biwersi J, Emans N, Verkman A. Cystic fibrosis transmembrane conductance regulator activation stimulates endosome fusion in vivo. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12484-9. PMID: 8901608; PMCID: PMC38018.
    453. Carter EP, Matthay MA, Farinas J, Verkman A. Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method. J Gen Physiol. 1996 Sep; 108(3):133-42. PMID: 8882859; PMCID: PMC2229323.
    454. Townsend RR, Lipniunas PH, Tulk BM, Verkman A. Identification of protein kinase A phosphorylation sites on NBD1 and R domains of CFTR using electrospray mass spectrometry with selective phosphate ion monitoring. Protein Sci. 1996 Sep; 5(9):1865-73. PMID: 8880910; PMCID: PMC2143550.
    455. Swaminathan R, Bicknese S, Periasamy N, Verkman A. Cytoplasmic viscosity near the cell plasma membrane: translational diffusion of a small fluorescent solute measured by total internal reflection-fluorescence photobleaching recovery. Biophys J. 1996 Aug; 71(2):1140-51. PMID: 8842251; PMCID: PMC1233569.
    456. Ma T, Yang B, Kuo WL, Verkman A. cDNA cloning and gene structure of a novel water channel expressed exclusively in human kidney: evidence for a gene cluster of aquaporins at chromosome locus 12q13. Genomics. 1996 Aug 1; 35(3):543-50. PMID: 8812490.
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    457. Emans N, Verkman A. Real-time fluorescence measurement of cell-free endosome fusion: regulation by second messengers. Biophys J. 1996 Jul; 71(1):487-94. PMID: 8804631; PMCID: PMC1233499.
    458. Seksek O, Biwersi J, Verkman A. Evidence against defective trans-Golgi acidification in cystic fibrosis. J Biol Chem. 1996 Jun 28; 271(26):15542-8. PMID: 8663158.
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    459. Brown CR, Hong-Brown LQ, Biwersi J, Verkman A, Welch WJ. Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein. Cell Stress Chaperones. 1996 Jun; 1(2):117-25. PMID: 9222597; PMCID: PMC248464.
    460. Umenishi F, Verkman A, Gropper MA. Quantitative analysis of aquaporin mRNA expression in rat tissues by RNase protection assay. DNA Cell Biol. 1996 Jun; 15(6):475-80. PMID: 8672243.
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    461. Ma T, Yang B, Verkman A. Gene structure, cDNA cloning, and expression of a mouse mercurial-insensitive water channel. Genomics. 1996 May 1; 33(3):382-8. PMID: 8660998.
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    462. Matthay MA, Folkesson HG, Verkman A. Salt and water transport across alveolar and distal airway epithelia in the adult lung. Am J Physiol. 1996 Apr; 270(4 Pt 1):L487-503. PMID: 8928808.
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    463. Kao HP, Verkman A. Construction and performance of a photobleaching recovery apparatus with microsecond time resolution. Biophys Chem. 1996 Mar 7; 59(1-2):203-10. PMID: 8867340.
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    464. Periasamy N, Bicknese S, Verkman A. Reversible photobleaching of fluorescein conjugates in air-saturated viscous solutions: singlet and triplet state quenching by tryptophan. Photochem Photobiol. 1996 Mar; 63(3):265-71. PMID: 8881329.
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    465. Yang B, Brown D, Verkman A. The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells. J Biol Chem. 1996 Mar 1; 271(9):4577-80. PMID: 8617713.
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    466. Folkesson HG, Matthay MA, Frigeri A, Verkman A. Transepithelial water permeability in microperfused distal airways. Evidence for channel-mediated water transport. J Clin Invest. 1996 Feb 1; 97(3):664-71. PMID: 8609221; PMCID: PMC507102.
    467. Shi LB, Verkman A. Selected cysteine point mutations confer mercurial sensitivity to the mercurial-insensitive water channel MIWC/AQP-4. Biochemistry. 1996 Jan 16; 35(2):538-44. PMID: 8555225.
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    468. Verkman A, van Hoek AN, Ma T, Frigeri A, Skach WR, Mitra A, Tamarappoo BK, Farinas J. Water transport across mammalian cell membranes. Am J Physiol. 1996 Jan; 270(1 Pt 1):C12-30. PMID: 8772426.
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    469. Verkman A. Optical methods to measure membrane transport processes. J Membr Biol. 1995 Nov; 148(2):99-110. PMID: 8606370.
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    470. Verkman A, Shi LB, Frigeri A, Hasegawa H, Farinas J, Mitra A, Skach W, Brown D, Van Hoek AN, Ma T. Structure and function of kidney water channels. Kidney Int. 1995 Oct; 48(4):1069-81. PMID: 8569068.
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    471. Yang B, Ma T, Verkman A. cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units. J Biol Chem. 1995 Sep 29; 270(39):22907-13. PMID: 7559426.
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    472. Mitra AK, van Hoek AN, Wiener MC, Verkman A, Yeager M. The CHIP28 water channel visualized in ice by electron crystallography. Nat Struct Biol. 1995 Sep; 2(9):726-9. PMID: 7552739.
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    473. Frigeri A, Gropper MA, Umenishi F, Kawashima M, Brown D, Verkman A. Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues. J Cell Sci. 1995 Sep; 108 ( Pt 9):2993-3002. PMID: 8537439.
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    474. Bicknese S, Rossi M, Thevenin B, Shohet SB, Verkman A. Anisotropy decay measurement of segmental dynamics of the anion binding domain in erythrocyte band 3. Biochemistry. 1995 Aug 22; 34(33):10645-51. PMID: 7544617.
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    475. Emans N, Biwersi J, Verkman A. Imaging of endosome fusion in BHK fibroblasts based on a novel fluorimetric avidin-biotin binding assay. Biophys J. 1995 Aug; 69(2):716-28. PMID: 8527685; PMCID: PMC1236296.
    476. Katsura T, Verbavatz JM, Farinas J, Ma T, Ausiello DA, Verkman A, Brown D. Constitutive and regulated membrane expression of aquaporin 1 and aquaporin 2 water channels in stably transfected LLC-PK1 epithelial cells. Proc Natl Acad Sci U S A. 1995 Aug 1; 92(16):7212-6. PMID: 7543677; PMCID: PMC41309.
    477. Shi LB, Skach WR, Ma T, Verkman A. Distinct biogenesis mechanisms for the water channels MIWC and CHIP28 at the endoplasmic reticulum. Biochemistry. 1995 Jul 4; 34(26):8250-6. PMID: 7541239.
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    478. Brown D, Katsura T, Kawashima M, Verkman A, Sabolic I. Cellular distribution of the aquaporins: a family of water channel proteins. Histochem Cell Biol. 1995 Jul; 104(1):1-9. PMID: 7584554.
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    479. Frigeri A, Gropper MA, Turck CW, Verkman A. Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proc Natl Acad Sci U S A. 1995 May 9; 92(10):4328-31. PMID: 7538665; PMCID: PMC41937.
    480. Bicknese S, Zimet D, Park J, van Hoek AN, Shohet SB, Verkman A. Detection of water proximity to tryptophan residues in proteins by single photon radioluminescence. Biophys Chem. 1995 May; 54(3):279-90. PMID: 7749062.
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    481. Farinas J, Simanek V, Verkman A. Cell volume measured by total internal reflection microfluorimetry: application to water and solute transport in cells transfected with water channel homologs. Biophys J. 1995 Apr; 68(4):1613-20. PMID: 7540430; PMCID: PMC1282057.
    482. Zimet DB, Thevenin BJ, Verkman A, Shohet SB, Abney JR. Calculation of resonance energy transfer in crowded biological membranes. Biophys J. 1995 Apr; 68(4):1592-603. PMID: 7787045; PMCID: PMC1282054.
    483. Seksek O, Biwersi J, Verkman A. Direct measurement of trans-Golgi pH in living cells and regulation by second messengers. J Biol Chem. 1995 Mar 10; 270(10):4967-70. PMID: 7890600.
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    484. van Hoek AN, Wiener MC, Verbavatz JM, Brown D, Lipniunas PH, Townsend RR, Verkman A. Purification and structure-function analysis of native, PNGase F-treated, and endo-beta-galactosidase-treated CHIP28 water channels. Biochemistry. 1995 Feb 21; 34(7):2212-9. PMID: 7532004.
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    485. Mitra AK, Yeager M, van Hoek AN, Wiener MC, Verkman A. Projection structure of the CHIP28 water channel in lipid bilayer membranes at 12-A resolution. Biochemistry. 1994 Nov 1; 33(43):12735-40. PMID: 7524655.
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    486. Kao HP, Verkman A. Tracking of single fluorescent particles in three dimensions: use of cylindrical optics to encode particle position. Biophys J. 1994 Sep; 67(3):1291-300. PMID: 7811944; PMCID: PMC1225486.
    487. Valenti G, Verbavatz JM, Sabolic I, Ausiello DA, Verkman A, Brown D. A basolateral CHIP28/MIP26-related protein (BLIP) in kidney principal cells and gastric parietal cells. Am J Physiol. 1994 Sep; 267(3 Pt 1):C812-20. PMID: 7524336.
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    488. Ma T, Frigeri A, Hasegawa H, Verkman A. Cloning of a water channel homolog expressed in brain meningeal cells and kidney collecting duct that functions as a stilbene-sensitive glycerol transporter. J Biol Chem. 1994 Aug 26; 269(34):21845-9. PMID: 8063828.
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    489. Folkesson HG, Matthay MA, Hasegawa H, Kheradmand F, Verkman A. Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):4970-4. PMID: 7515184; PMCID: PMC43911.
    490. Biwersi J, Tulk B, Verkman A. Long-wavelength chloride-sensitive fluorescent indicators. Anal Biochem. 1994 May 15; 219(1):139-43. PMID: 8059940.
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    491. Skach WR, Shi LB, Calayag MC, Frigeri A, Lingappa VR, Verkman A. Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum. J Cell Biol. 1994 May; 125(4):803-15. PMID: 7514605; PMCID: PMC2120064.
    492. Shi LB, Skach WR, Verkman A. Functional independence of monomeric CHIP28 water channels revealed by expression of wild-type mutant heterodimers. J Biol Chem. 1994 Apr 8; 269(14):10417-22. PMID: 7511600.
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    493. Hasegawa H, Lian SC, Finkbeiner WE, Verkman A. Extrarenal tissue distribution of CHIP28 water channels by in situ hybridization and antibody staining. Am J Physiol. 1994 Apr; 266(4 Pt 1):C893-903. PMID: 7513954.
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    494. Verbavatz JM, Van Hoek AN, Ma T, Sabolic I, Valenti G, Ellisman MH, Ausiello DA, Verkman A, Brown D. A 28 kDa sarcolemmal antigen in kidney principal cell basolateral membranes: relationship to orthogonal arrays and MIP26. J Cell Sci. 1994 Apr; 107 ( Pt 4):1083-94. PMID: 7520041.
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    495. Thevenin BJ, Periasamy N, Shohet SB, Verkman A. Segmental dynamics of the cytoplasmic domain of erythrocyte band 3 determined by time-resolved fluorescence anisotropy: sensitivity to pH and ligand binding. Proc Natl Acad Sci U S A. 1994 Mar 1; 91(5):1741-5. PMID: 8127875; PMCID: PMC43239.
    496. Hasegawa H, Ma T, Skach W, Matthay MA, Verkman A. Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. J Biol Chem. 1994 Feb 25; 269(8):5497-500. PMID: 7509789.
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    497. Ma T, Hasegawa H, Skach WR, Frigeri A, Verkman A. Expression, functional analysis, and in situ hybridization of a cloned rat kidney collecting duct water channel. Am J Physiol. 1994 Jan; 266(1 Pt 1):C189-97. PMID: 7508187.
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    498. Biwersi J, Verkman A. Functional CFTR in endosomal compartment of CFTR-expressing fibroblasts and T84 cells. Am J Physiol. 1994 Jan; 266(1 Pt 1):C149-56. PMID: 7508186.
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    499. Ma T, Frigeri A, Skach W, Verkman A. Cloning of a novel rat kidney cDNA homologous to CHIP28 and WCH-CD water channels. Biochem Biophys Res Commun. 1993 Dec 15; 197(2):654-9. PMID: 7505572.
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    500. Farinas J, Van Hoek AN, Shi LB, Erickson C, Verkman A. Nonpolar environment of tryptophans in erythrocyte water channel CHIP28 determined by fluorescence quenching. Biochemistry. 1993 Nov 9; 32(44):11857-64. PMID: 8218257.
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    501. Van Hoek AN, Wiener M, Bicknese S, Miercke L, Biwersi J, Verkman A. Secondary structure analysis of purified functional CHIP28 water channels by CD and FTIR spectroscopy. Biochemistry. 1993 Nov 9; 32(44):11847-56. PMID: 8218256.
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    502. Verbavatz JM, Brown D, Sabolic I, Valenti G, Ausiello DA, Van Hoek AN, Ma T, Verkman A. Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study. J Cell Biol. 1993 Nov; 123(3):605-18. PMID: 7693713; PMCID: PMC2200118.
    503. Ma T, Frigeri A, Tsai ST, Verbavatz JM, Verkman A. Localization and functional analysis of CHIP28k water channels in stably transfected Chinese hamster ovary cells. J Biol Chem. 1993 Oct 25; 268(30):22756-64. PMID: 8226786.
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    504. Bicknese S, Periasamy N, Shohet SB, Verkman A. Cytoplasmic viscosity near the cell plasma membrane: measurement by evanescent field frequency-domain microfluorimetry. Biophys J. 1993 Sep; 65(3):1272-82. PMID: 8241407; PMCID: PMC1225847.
    505. Hasegawa H, Verkman A. Functional expression of cAMP-dependent and independent urea transporters in Xenopus oocytes. Am J Physiol. 1993 Aug; 265(2 Pt 1):C514-20. PMID: 8396330.
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    506. Zhang R, van Hoek AN, Biwersi J, Verkman A. A point mutation at cysteine 189 blocks the water permeability of rat kidney water channel CHIP28k. Biochemistry. 1993 Mar 30; 32(12):2938-41. PMID: 8457558.
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    507. Kao HP, Abney JR, Verkman A. Determinants of the translational mobility of a small solute in cell cytoplasm. J Cell Biol. 1993 Jan; 120(1):175-84. PMID: 8416987; PMCID: PMC2119503.
    508. Zhang R, Skach W, Hasegawa H, van Hoek AN, Verkman A. Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28. J Cell Biol. 1993 Jan; 120(2):359-69. PMID: 8421053; PMCID: PMC2119509.
    509. Hasegawa H, Zhang R, Dohrman A, Verkman A. Tissue-specific expression of mRNA encoding rat kidney water channel CHIP28k by in situ hybridization. Am J Physiol. 1993 Jan; 264(1 Pt 1):C237-45. PMID: 7679251.
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    510. Sabolic I, Valenti G, Verbavatz JM, Van Hoek AN, Verkman A, Ausiello DA, Brown D. Localization of the CHIP28 water channel in rat kidney. Am J Physiol. 1992 Dec; 263(6 Pt 1):C1225-33. PMID: 1282299.
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    511. Hasegawa H, Skach W, Baker O, Calayag MC, Lingappa V, Verkman A. A multifunctional aqueous channel formed by CFTR. Science. 1992 Nov 27; 258(5087):1477-9. PMID: 1279809.
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    512. Bicknese S, Shahrokh Z, Shohet SB, Verkman A. Single photon radioluminescence. I. Theory and spectroscopic properties. Biophys J. 1992 Nov; 63(5):1256-66. PMID: 1477277; PMCID: PMC1261428.
    513. Shahrokh Z, Bicknese S, Shohet SB, Verkman A. Single photon radioluminescence. II. Signal detection and biological applications. Biophys J. 1992 Nov; 63(5):1267-79. PMID: 1477278; PMCID: PMC1261429.
    514. Periasamy N, Kao HP, Fushimi K, Verkman A. Organic osmolytes increase cytoplasmic viscosity in kidney cells. Am J Physiol. 1992 Oct; 263(4 Pt 1):C901-7. PMID: 1415675.
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    515. Sabolic I, Wuarin F, Shi LB, Verkman A, Ausiello DA, Gluck S, Brown D. Apical endosomes isolated from kidney collecting duct principal cells lack subunits of the proton pumping ATPase. J Cell Biol. 1992 Oct; 119(1):111-22. PMID: 1388176; PMCID: PMC2289636.
    516. Zen K, Biwersi J, Periasamy N, Verkman A. Second messengers regulate endosomal acidification in Swiss 3T3 fibroblasts. J Cell Biol. 1992 Oct; 119(1):99-110. PMID: 1382079; PMCID: PMC2289635.
    517. van Hoek AN, Verkman A. Functional reconstitution of the isolated erythrocyte water channel CHIP28. J Biol Chem. 1992 Sep 15; 267(26):18267-9. PMID: 1526967.
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    518. Echevarria M, Verkman A. Optical measurement of osmotic water transport in cultured cells. Role of glucose transporters. J Gen Physiol. 1992 Apr; 99(4):573-89. PMID: 1597679; PMCID: PMC2219203.
    519. Periasamy N, Verkman A. Subtraction of background fluorescence in multiharmonic frequency-domain fluorimetry. Anal Biochem. 1992 Feb 14; 201(1):107-13. PMID: 1621947.
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    520. Hartmann T, Kondo M, Mochizuki H, Verkman A, Widdicombe JH. Calcium-dependent regulation of Cl secretion in tracheal epithelium. Am J Physiol. 1992 Feb; 262(2 Pt 1):L163-8. PMID: 1311517.
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    521. Reenstra WW, Sabolic I, Bae HR, Verkman A. Protein kinase A dependent membrane protein phosphorylation and chloride conductance in endosomal vesicles from kidney cortex. Biochemistry. 1992 Jan 14; 31(1):175-81. PMID: 1310027.
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    522. Sabolic I, Shi LB, Brown D, Ausiello DA, Verkman A. Proteinases inhibit H(+)-ATPase and Na+/H+ exchange but not water transport in apical and endosomal membranes from rat proximal tubule. Biochim Biophys Acta. 1992 Jan 10; 1103(1):137-47. PMID: 1309658.
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    523. Hartmann T, Verkman A. Construction and performance of a rapid scan monochromator for multiwavelength fluorimetry. Anal Biochem. 1992 Jan; 200(1):139-42. PMID: 1595888.
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    524. Verkman A, Chao AC, Hartmann T. Hormonal regulation of Cl transport in polar airway epithelia measured by a fluorescent indicator. Am J Physiol. 1992 Jan; 262(1 Pt 1):C23-31. PMID: 1310213.
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    525. Biwersi J, Farah N, Wang YX, Ketcham R, Verkman A. Synthesis of cell-impermeable Cl-sensitive fluorescent indicators with improved sensitivity and optical properties. Am J Physiol. 1992 Jan; 262(1 Pt 1):C242-50. PMID: 1370743.
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    526. Verkman A. Water channels in cell membranes. Annu Rev Physiol. 1992; 54:97-108. PMID: 1373280.
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    527. Periasamy N, Armijo M, Verkman A. Picosecond rotation of small polar fluorophores in the cytosol of sea urchin eggs. Biochemistry. 1991 Dec 24; 30(51):11836-41. PMID: 1751500.
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    528. Zhang R, Alper SL, Thorens B, Verkman A. Evidence from oocyte expression that the erythrocyte water channel is distinct from band 3 and the glucose transporter. J Clin Invest. 1991 Nov; 88(5):1553-8. PMID: 1939644; PMCID: PMC295670.
    529. Biwersi J, Verkman A. Cell-permeable fluorescent indicator for cytosolic chloride. Biochemistry. 1991 Aug 13; 30(32):7879-83. PMID: 1868062.
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    530. Shi LB, Fushimi K, Verkman A. Solvent drag measurement of transcellular and basolateral membrane NaCl reflection coefficient in kidney proximal tubule. J Gen Physiol. 1991 Aug; 98(2):379-98. PMID: 1940854; PMCID: PMC2229051.
    531. Kuwahara M, Shi LB, Marumo F, Verkman A. Transcellular water flow modulates water channel exocytosis and endocytosis in kidney collecting tubule. J Clin Invest. 1991 Aug; 88(2):423-9. PMID: 1864956; PMCID: PMC295348.
    532. Verkman A, Shi LB, Bae HR, Fushimi K. Transport mechanisms in kidney proximal tubule examined using chloride-sensitive fluorescent indicators. Kidney Int Suppl. 1991 Jul; 33:S103-8. PMID: 1890794.
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    533. Shahrokh Z, Verkman A, Shohet SB. Distance between skeletal protein 4.1 and the erythrocyte membrane bilayer measured by resonance energy transfer. J Biol Chem. 1991 Jun 25; 266(18):12082-9. PMID: 2050702.
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    534. Shi LB, Fushimi K, Bae HR, Verkman A. Heterogeneity in ATP-dependent acidification in endocytic vesicles from kidney proximal tubule. Measurement of pH in individual endocytic vesicles in a cell-free system. Biophys J. 1991 Jun; 59(6):1208-17. PMID: 1714779; PMCID: PMC1281201.
    535. Verkman A, Armijo M, Fushimi K. Construction and evaluation of a frequency-domain epifluorescence microscope for lifetime and anisotropy decay measurements in subcellular domains. Biophys Chem. 1991 Apr; 40(1):117-25. PMID: 1873470.
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    536. Wang YX, Shi LB, Verkman A. Functional water channels and proton pumps are in separate populations of endocytic vesicles in toad bladder granular cells. Biochemistry. 1991 Mar 19; 30(11):2888-94. PMID: 1901021.
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    537. Tsai ST, Zhang RB, Verkman A. High channel-mediated water permeability in rabbit erythrocytes: characterization in native cells and expression in Xenopus oocytes. Biochemistry. 1991 Feb 26; 30(8):2087-92. PMID: 1847825.
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    538. Fushimi K, Verkman A. Low viscosity in the aqueous domain of cell cytoplasm measured by picosecond polarization microfluorimetry. J Cell Biol. 1991 Feb; 112(4):719-25. PMID: 1993739; PMCID: PMC2288848.
    539. Fushimi K, Verkman A. Relationship between vasopressin-sensitive water transport and plasma membrane fluidity in kidney collecting tubule. Am J Physiol. 1991 Jan; 260(1 Pt 1):C1-8. PMID: 1987773.
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    540. Zhang RB, Verkman A. Water and urea permeability properties of Xenopus oocytes: expression of mRNA from toad urinary bladder. Am J Physiol. 1991 Jan; 260(1 Pt 1):C26-34. PMID: 1987778.
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    541. Bae HR, Verkman A. Protein kinase A regulates chloride conductance in endocytic vesicles from proximal tubule. Nature. 1990 Dec 13; 348(6302):637-9. PMID: 1701220.
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    542. Lencer WI, Brown D, Ausiello DA, Verkman A. Endocytosis of water channels in rat kidney: cell specificity and correlation with in vivo antidiuresis. Am J Physiol. 1990 Dec; 259(6 Pt 1):C920-32. PMID: 1701969.
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    543. Shi LB, Wang YX, Verkman A. Regulation of the formation and water permeability of endosomes from toad bladder granular cells. J Gen Physiol. 1990 Oct; 96(4):789-808. PMID: 1979609; PMCID: PMC2229009.
    544. Zhang RB, Logee KA, Verkman A. Expression of mRNA coding for kidney and red cell water channels in Xenopus oocytes. J Biol Chem. 1990 Sep 15; 265(26):15375-8. PMID: 2394728.
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    545. Zhang RB, Verkman A. Urea transport in freshly isolated and cultured cells from rat inner medullary collecting duct. J Membr Biol. 1990 Sep; 117(3):253-61. PMID: 2172546.
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    546. Verkman A. Development and biological applications of chloride-sensitive fluorescent indicators. Am J Physiol. 1990 Sep; 259(3 Pt 1):C375-88. PMID: 2205105.
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    547. Hartmann T, Verkman A. Model of ion transport regulation in chloride-secreting airway epithelial cells. Integrated description of electrical, chemical, and fluorescence measurements. Biophys J. 1990 Aug; 58(2):391-401. PMID: 1698471; PMCID: PMC1280980.
    548. Lencer WI, Verkman A, Arnaout MA, Ausiello DA, Brown D. Endocytic vesicles from renal papilla which retrieve the vasopressin-sensitive water channel do not contain a functional H+ ATPase. J Cell Biol. 1990 Aug; 111(2):379-89. PMID: 1696262; PMCID: PMC2116183.
    549. Shi LB, Brown D, Verkman A. Water, proton, and urea transport in toad bladder endosomes that contain the vasopressin-sensitive water channel. J Gen Physiol. 1990 May; 95(5):941-60. PMID: 2163434; PMCID: PMC2216342.
    550. Roe JN, Szoka FC, Verkman A. Fibre optic sensor for the detection of potassium using fluorescence energy transfer. Analyst. 1990 Apr; 115(4):353-8. PMID: 2363517.
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    551. Shi LB, Ye RG, Lencer WI, Verkman A. [Characterization of proton pump and osmotic water transport in endocytic vesicles from rat kidney proximal tubule]. Sheng Li Xue Bao. 1990 Apr; 42(2):105-13. PMID: 2142810.
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    552. Dix JA, Verkman A. Pyrene eximer mapping in cultured fibroblasts by ratio imaging and time-resolved microscopy. Biochemistry. 1990 Feb 20; 29(7):1949-53. PMID: 2331474.
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    553. Chao AC, Widdicombe JH, Verkman A. Chloride conductive and cotransport mechanisms in cultures of canine tracheal epithelial cells measured by an entrapped fluorescent indicator. J Membr Biol. 1990 Feb; 113(3):193-202. PMID: 2335807.
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    554. Dix JA, Verkman A. Mapping of fluorescence anisotropy in living cells by ratio imaging. Application to cytoplasmic viscosity. Biophys J. 1990 Feb; 57(2):231-40. PMID: 2317548; PMCID: PMC1280665.
    555. Fushimi K, Dix JA, Verkman A. Cell membrane fluidity in the intact kidney proximal tubule measured by orientation-independent fluorescence anisotropy imaging. Biophys J. 1990 Feb; 57(2):241-54. PMID: 2317549; PMCID: PMC1280666.
    556. Lencer WI, Weyer P, Verkman A, Ausiello DA, Brown D. FITC-dextran as a probe for endosome function and localization in kidney. Am J Physiol. 1990 Feb; 258(2 Pt 1):C309-17. PMID: 1689545.
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    557. Brown D, Verkman A, Skorecki K, Ausiello D. The cellular action of antidiuretic hormone. Methods Enzymol. 1990; 191:551-71. PMID: 2074776.
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    558. Verkman A, Weyer P, Brown D, Ausiello DA. Functional water channels are present in clathrin-coated vesicles from bovine kidney but not from brain. J Biol Chem. 1989 Dec 5; 264(34):20608-13. PMID: 2573601.
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    559. Chao AC, Dix JA, Sellers MC, Verkman A. Fluorescence measurement of chloride transport in monolayer cultured cells. Mechanisms of chloride transport in fibroblasts. Biophys J. 1989 Dec; 56(6):1071-81. PMID: 2482083; PMCID: PMC1280611.
    560. Shi LB, Verkman A. Very high water permeability in vasopressin-induced endocytic vesicles from toad urinary bladder. J Gen Physiol. 1989 Dec; 94(6):1101-15. PMID: 2515241; PMCID: PMC2228947.
    561. Verkman A. Mechanisms and regulation of water permeability in renal epithelia. Am J Physiol. 1989 Nov; 257(5 Pt 1):C837-50. PMID: 2688434.
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    562. Kuwahara M, Verkman A. Pre-steady-state analysis of the turn-on and turn-off of water permeability in the kidney collecting tubule. J Membr Biol. 1989 Aug; 110(1):57-65. PMID: 2795641.
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    563. Holmberg EG, Verkman A, Dix JA. Mechanism of acridine orange interaction with phospholipids and proteins in renal microvillus vesicles. Biophys Chem. 1989 Jul; 33(3):245-56. PMID: 2804243.
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    564. Roe JN, Szoka FC, Verkman A. Optical measurement of aqueous potassium concentration by a hydrophobic indicator in lipid vesicles. Biophys Chem. 1989 Jul; 33(3):295-302. PMID: 2804247.
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    565. Calafut TM, Dix JA, Verkman A. Fluorescence depolarization of cis- and trans-parinaric acids in artificial and red cell membranes resolved by a double hindered rotational model. Biochemistry. 1989 Jun 13; 28(12):5051-8. PMID: 2765524.
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    566. Pearce D, Verkman A. NaCl reflection coefficients in proximal tubule apical and basolateral membrane vesicles. Measurement by induced osmosis and solvent drag. Biophys J. 1989 Jun; 55(6):1251-9. PMID: 2765660; PMCID: PMC1330589.
    567. Verkman A, Takla R, Sefton B, Basbaum C, Widdicombe JH. Quantitative fluorescence measurement of chloride transport mechanisms in phospholipid vesicles. Biochemistry. 1989 May 16; 28(10):4240-4. PMID: 2765484.
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    568. Ye RG, Shi LB, Lencer WI, Verkman A. Functional colocalization of water channels and proton pumps in endosomes from kidney proximal tubule. J Gen Physiol. 1989 May; 93(5):885-902. PMID: 2472463; PMCID: PMC2216239.
    569. Verkman A, Sellers MC, Chao AC, Leung T, Ketcham R. Synthesis and characterization of improved chloride-sensitive fluorescent indicators for biological applications. Anal Biochem. 1989 May 1; 178(2):355-61. PMID: 2751097.
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    570. Ye RG, Verkman A. Simultaneous optical measurement of osmotic and diffusional water permeability in cells and liposomes. Biochemistry. 1989 Jan 24; 28(2):824-9. PMID: 2540807.
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    571. Illsley NP, Glaubensklee C, Davis B, Verkman A. Chloride transport across placental microvillous membranes measured by fluorescence. Am J Physiol. 1988 Dec; 255(6 Pt 1):C789-97. PMID: 3202148.
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    572. Illsley NP, Goodman JG, Verkman A, Davis B. Macromolecule entrapment in human placental microvillous membrane vesicles. Anal Biochem. 1988 Nov 15; 175(1):106-13. PMID: 2469349.
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    573. Kuwahara M, Verkman A. Direct fluorescence measurement of diffusional water permeability in the vasopressin-sensitive kidney collecting tubule. Biophys J. 1988 Oct; 54(4):587-93. PMID: 3224144; PMCID: PMC1330362.
    574. Berry CA, Verkman A. Osmotic gradient dependence of osmotic water permeability in rabbit proximal convoluted tubule. J Membr Biol. 1988 Oct; 105(1):33-43. PMID: 2852255.
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    575. Kuwahara M, Berry CA, Verkman A. Rapid development of vasopressin-induced hydroosmosis in kidney collecting tubules measured by a new fluorescence technique. Biophys J. 1988 Oct; 54(4):595-602. PMID: 3224145; PMCID: PMC1330363.
    576. Fong P, Illsley NP, Widdicombe JH, Verkman A. Chloride transport in apical membrane vesicles from bovine tracheal epithelium: characterization using a fluorescent indicator. J Membr Biol. 1988 Sep; 104(3):233-9. PMID: 3210223.
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    577. Verkman A, Masur SK. Very low osmotic water permeability and membrane fluidity in isolated toad bladder granules. J Membr Biol. 1988 Sep; 104(3):241-51. PMID: 3145339.
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    578. Kim YK, Illsley NP, Verkman A. Rapid fluorescence assay of glucose and neutral solute transport using an entrapped volume indicator. Anal Biochem. 1988 Aug 1; 172(2):403-9. PMID: 3189785.
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    579. Chen PY, Pearce D, Verkman A. Membrane water and solute permeability determined quantitatively by self-quenching of an entrapped fluorophore. Biochemistry. 1988 Jul 26; 27(15):5713-8. PMID: 3179272.
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    580. Krapf R, Berry CA, Verkman A. Estimation of intracellular chloride activity in isolated perfused rabbit proximal convoluted tubules using a fluorescent indicator. Biophys J. 1988 Jun; 53(6):955-62. PMID: 3395662; PMCID: PMC1330276.
    581. Verkman A, Lencer WI, Brown D, Ausiello DA. Endosomes from kidney collecting tubule cells contain the vasopressin-sensitive water channel. Nature. 1988 May 19; 333(6170):268-9. PMID: 3368004.
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    582. Illsley NP, Lin HY, Verkman A. Lipid-phase structure in epithelial cell membranes: comparison of renal brush border and basolateral membranes. Biochemistry. 1988 Mar 22; 27(6):2077-83. PMID: 3378045.
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    583. Krapf R, Illsley NP, Tseng HC, Verkman A. Structure-activity relationships of chloride-sensitive fluorescent indicators for biological application. Anal Biochem. 1988 Feb 15; 169(1):142-50. PMID: 3369678.
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    584. Chen PY, Verkman A. Sodium-dependent chloride transport in basolateral membrane vesicles isolated from rabbit proximal tubule. Biochemistry. 1988 Jan 26; 27(2):655-60. PMID: 3349054.
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    585. Chen PY, Illsley NP, Verkman A. Renal brush-border chloride transport mechanisms characterized using a fluorescent indicator. Am J Physiol. 1988 Jan; 254(1 Pt 2):F114-20. PMID: 3337241.
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    586. Ausiello DA, Verkman A, Skorecki KL. Vasopressin-sensitive adenylate cyclase: subunit interactions assessed by target analysis and computer modelling. Kidney Int Suppl. 1987 Dec; 23:S43-55. PMID: 3126336.
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    587. Verkman A. Passive H+/OH- permeability in epithelial brush border membranes. J Bioenerg Biomembr. 1987 Oct; 19(5):481-93. PMID: 2826411.
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    588. Verkman A. Mechanism and kinetics of merocyanine 540 binding to phospholipid membranes. Biochemistry. 1987 Jun 30; 26(13):4050-6. PMID: 3651436.
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    589. Wong KR, Verkman A. Human platelet diffusional water permeability measured by nuclear magnetic resonance. Am J Physiol. 1987 Jun; 252(6 Pt 1):C618-22. PMID: 3591932.
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    590. Verkman A, Wong KR. Proton nuclear magnetic resonance measurement of diffusional water permeability in suspended renal proximal tubules. Biophys J. 1987 May; 51(5):717-23. PMID: 3593869; PMCID: PMC1329959.
    591. Chen PY, Verkman A. Non-electrolyte transport across renal proximal tubule cell membranes measured by tracer efflux and light scattering. Pflugers Arch. 1987 May; 408(5):491-6. PMID: 3110738.
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    592. Verkman A, Alpern RJ. Kinetic transport model for cellular regulation of pH and solute concentration in the renal proximal tubule. Biophys J. 1987 Apr; 51(4):533-46. PMID: 3580482; PMCID: PMC1329926.
    593. Illsley NP, Verkman A. Membrane chloride transport measured using a chloride-sensitive fluorescent probe. Biochemistry. 1987 Mar 10; 26(5):1215-9. PMID: 3567167.
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    594. Ausiello DA, Skorecki KL, Verkman A, Bonventre JV. Vasopressin signaling in kidney cells. Kidney Int. 1987 Feb; 31(2):521-9. PMID: 2951552.
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    595. Illsley NP, Lin HY, Verkman A. Lipid domain structure correlated with membrane protein function in placental microvillus vesicles. Biochemistry. 1987 Jan 27; 26(2):446-54. PMID: 3828317.
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    596. Skorecki KL, Verkman A, Ausiello DA. Cross talk between stimulatory and inhibitory guanosine 5'-triphosphate binding proteins: role in activation and desensitization of the adenylate cyclase response to vasopressin. Biochemistry. 1987 Jan 27; 26(2):639-45. PMID: 3103683.
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    597. Meyer MM, Verkman A. Evidence for water channels in renal proximal tubule cell membranes. J Membr Biol. 1987; 96(2):107-19. PMID: 3599063.
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    598. Chen PY, Verkman A. Renal basolateral membrane anion transporter characterized by a fluorescent disulfonic stilbene. J Membr Biol. 1987; 100(1):1-12. PMID: 2448466.
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    599. Ives HE, Chen PY, Verkman A. Mechanism of coupling between Cl- and OH- transport in renal brush-border membranes. Biochim Biophys Acta. 1986 Dec 1; 863(1):91-100. PMID: 3778914.
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    600. Cabrini G, Verkman A. Localization of cyanine dye binding to brush-border membranes by quenching of n-(9-anthroyloxy) fatty acid probes. Biochim Biophys Acta. 1986 Nov 17; 862(2):285-93. PMID: 3778893.
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    601. Cabrini G, Illsley NP, Verkman A. External anions regulate stilbene-sensitive proton transport in placental brush border vesicles. Biochemistry. 1986 Oct 7; 25(20):6300-5. PMID: 3024705.
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    602. Meyer MM, Verkman A. Human platelet osmotic water and nonelectrolyte transport. Am J Physiol. 1986 Oct; 251(4 Pt 1):C549-57. PMID: 3766720.
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    603. Verkman A, Skorecki KL, Jung CY, Ausiello DA. Target molecular weights for red cell band 3 stilbene and mercurial binding sites. Am J Physiol. 1986 Oct; 251(4 Pt 1):C541-8. PMID: 3020989.
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    604. Verkman A, Ausiello DA, Jung CY, Skorecki KL. Mechanisms of nonhormonal activation of adenylate cyclase based on target analysis. Biochemistry. 1986 Aug 12; 25(16):4566-72. PMID: 3768298.
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    605. Verkman A, Ives HE. Anomalous driving force for renal brush border H+/OH-transport characterized by using 6-carboxyfluorescein. Biochemistry. 1986 May 20; 25(10):2876-82. PMID: 3013286.
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    606. Verkman A, Ives HE. Water permeability and fluidity of renal basolateral membranes. Am J Physiol. 1986 Apr; 250(4 Pt 2):F633-43. PMID: 3963203.
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    607. Verkman A, Fraser CL. Water and nonelectrolyte permeability in brain synaptosomes isolated from normal and uremic rats. Am J Physiol. 1986 Feb; 250(2 Pt 2):R306-12. PMID: 3946644.
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    608. Cabrini G, Verkman A. Mechanism of interaction of the cyanine dye diS-C3-(5) with renal brush-border vesicles. J Membr Biol. 1986; 90(2):163-75. PMID: 3723592.
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    609. Illsley NP, Verkman A. Serial permeability barriers to water transport in human placental vesicles. J Membr Biol. 1986; 94(3):267-78. PMID: 2435911.
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    610. Skorecki KL, Verkman A, Ausiello DA. Vasopressin receptor-adenylate cyclase interactions. Studies in an intact cultured renal epithelial cell line (LLC-PK1). Miner Electrolyte Metab. 1986; 12(1):64-70. PMID: 3007962.
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    611. Verkman A, Lukacovic MF, Tinklepaugh MS, Dix JA. Quenching of red cell tryptophan fluorescence by mercurial compounds. Membr Biochem. 1986; 6(4):269-89. PMID: 3574139.
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    612. Cabrini G, Verkman A. Potential-sensitive response mechanism of diS-C3-(5) in biological membranes. J Membr Biol. 1986; 92(2):171-82. PMID: 3761361.
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    613. Skorecki KL, Verkman A, Jung CY, Ausiello DA. Evidence for vasopressin activation of adenylate cyclase by subunit dissociation. Am J Physiol. 1986 Jan; 250(1 Pt 1):C115-23. PMID: 3942202.
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    614. Verkman A, Skorecki KL, Ausiello DA. Radiation inactivation of multimeric enzymes: application to subunit interactions of adenylate cyclase. Am J Physiol. 1986 Jan; 250(1 Pt 1):C103-14. PMID: 3942201.
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    615. Dix JA, Verkman A, Solomon AK. Binding of chloride and a disulfonic stilbene transport inhibitor to red cell band 3. J Membr Biol. 1986; 89(3):211-23. PMID: 3701841.
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    616. Dix JA, Ausiello DA, Jung CY, Verkman A. Target analysis studies of red cell water and urea transport. Biochim Biophys Acta. 1985 Dec 5; 821(2):243-52. PMID: 2998469.
      View in: PubMed
    617. Verkman A, Frosch MP. Temperature-jump studies of merocyanine 540 relaxation kinetics in lipid bilayer membranes. Biochemistry. 1985 Dec 3; 24(25):7117-22. PMID: 4084566.
      View in: PubMed
    618. Ives HE, Verkman A. Effects of membrane fluidizing agents on renal brush border proton permeability. Am J Physiol. 1985 Dec; 249(6 Pt 2):F933-40. PMID: 4073275.
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    619. Verkman A, Dix JA, Seifter JL, Skorecki KL, Jung CY, Ausiello DA. Radiation inactivation studies of renal brush border water and urea transport. Am J Physiol. 1985 Dec; 249(6 Pt 2):F806-12. PMID: 3934983.
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    620. Forman SA, Verkman A, Dix JA, Solomon AK. n-Alkanols and halothane inhibit red cell anion transport and increase band 3 conformational change rate. Biochemistry. 1985 Aug 27; 24(18):4859-66. PMID: 4074663.
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    621. Verkman A, Dix JA, Seifter JL. Water and urea transport in renal microvillus membrane vesicles. Am J Physiol. 1985 May; 248(5 Pt 2):F650-5. PMID: 3993788.
      View in: PubMed
    622. Lukacovic MF, Verkman A, Dix JA, Solomon AK. Specific interaction of the water transport inhibitor, pCMBS, with band 3 in red blood cell membranes. Biochim Biophys Acta. 1984 Dec 5; 778(2):253-9. PMID: 6093883.
      View in: PubMed
    623. Verkman A, Dix JA. Effect of unstirred layers on binding and reaction kinetics at a membrane surface. Anal Biochem. 1984 Oct; 142(1):109-16. PMID: 6517306.
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    624. Verkman A, Skorecki K, Ausiello DA. Radiation inactivation of oligomeric enzyme systems: theoretical considerations. Proc Natl Acad Sci U S A. 1984 Jan; 81(1):150-4. PMID: 6582472; PMCID: PMC344628.
    625. Verkman A, Dix JA, Solomon AK. Anion transport inhibitor binding to band 3 in red blood cell membranes. J Gen Physiol. 1983 Mar; 81(3):421-49. PMID: 6842178; PMCID: PMC2215580.
    626. Solomon AK, Chasan B, Dix JA, Lukacovic MF, Toon MR, Verkman A. The aqueous pore in the red cell membrane: band 3 as a channel for anions, cations, nonelectrolytes, and water. Ann N Y Acad Sci. 1983; 414:97-124. PMID: 6322657.
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    627. Verkman A, Solomon AK. A stepwise mechanism for the permeation of phloretin through a lipid bilayer. J Gen Physiol. 1982 Oct; 80(4):557-81. PMID: 7142954; PMCID: PMC2228705.
    628. Forman SA, Verkman A, Dix JA, Solomon AK. Interaction of phloretin with the anion transport protein of the red blood cell membrane. Biochim Biophys Acta. 1982 Aug 12; 689(3):531-8. PMID: 7126563.
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    629. Verkman A, Dix JA, Pandiscio AA. A simple stopped-flow temperature-jump apparatus. Anal Biochem. 1981 Oct; 117(1):164-9. PMID: 7316188.
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    630. Verkman A. The quenching of an intramembrane fluorescent probe. A method to study the binding and permeation of phloretin through bilayers. Biochim Biophys Acta. 1980 Jul; 599(2):370-9. PMID: 7407100.
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    631. Verkman A, Solomon AK. Kinetics of phloretin binding to phosphatidylcholine vesicle membranes. J Gen Physiol. 1980 Jun; 75(6):673-92. PMID: 7391812; PMCID: PMC2215264.
    632. Verkman A, Pandiscio AA, Jennings M, Solomon AK. An improved temperature-jump apparatus. Anal Biochem. 1980 Feb; 102(1):189-95. PMID: 7356153.
      View in: PubMed
    633. Dix JA, Verkman A, Solomon AK, Cantley LC. Human erythrocyte anion exchange site characterised using a fluorescent probe. Nature. 1979 Nov 29; 282(5738):520-2. PMID: 503233.
      View in: PubMed
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