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Joseph Cuschieri, MD, FACS

Title(s)Professor in Residence, Surgery
SchoolSchool of Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Aspirin versus anticoagulation for stroke prophylaxis in blunt cerebrovascular injury: a propensity-matched retrospective cohort study. J Neurosurg. 2021 Mar 26; 1-8. Bonow RH, Witt CE, Mossa-Basha M, Cuschieri J, Arbabi S, Vavilala MS, Rivara FP, Chesnut RM. PMID: 33770758.
      View in: PubMed   Mentions:    Fields:    
    2. PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients. BMJ Open. 2021 Mar 24; 11(3):e041845. O'Toole RV, Stein DM, Frey KP, O'Hara NN, Scharfstein DO, Slobogean GP, Taylor TJ, Haac BE, Carlini AR, Manson TT, Sudini K, Mullins CD, Wegener ST, Firoozabadi R, Haut ER, Bosse MJ, Seymour RB, Holden MB, Gitajn IL, Goldhaber SZ, Eastman AL, Jurkovich GJ, Vallier HA, Gary JL, Kleweno CP, Cuschieri J, Marvel D, Castillo RC, METRC . PMID: 33762229.
      View in: PubMed   Mentions:    Fields:    
    3. Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document. Trauma Surg Acute Care Open. 2021; 6(1):e000643. Rappold JF, Sheppard FR, Carmichael Ii SP, Cuschieri J, Ley E, Rangel E, Seshadri AJ, Michetti CP. PMID: 33718615.
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    4. Distinct immunologic endotypes are associated with clinical trajectory after severe blunt trauma and hemorrhagic shock. J Trauma Acute Care Surg. 2021 Feb 01; 90(2):257-267. PMID: 33214489.
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    5. Persistent metabolomic alterations characterize chronic critical illness after severe trauma. J Trauma Acute Care Surg. 2021 Jan 01; 90(1):35-45. PMID: 33017357.
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    6. The Covid-19 Pandemic: Lessons Learned for Sustained Trauma Preparedness and Responses. Ann Surg. 2020 Dec 23; Publish Ahead of Print. PMID: 33378302.
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    7. Changes in error patterns in unanticipated trauma deaths during 20 years: In pursuit of zero preventable deaths. J Trauma Acute Care Surg. 2020 12; 89(6):1046-1053. PMID: 32773673.
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    8. A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis. N Engl J Med. 2020 11 12; 383(20):1907-1919. , Flum DR, Davidson GH, Monsell SE, Shapiro NI, Odom SR, Sanchez SE, Drake FT, Fischkoff K, Johnson J, Patton JH, Evans H, Cuschieri J, Sabbatini AK, Faine BA, Skeete DA, Liang MK, Sohn V, McGrane K, Kutcher ME, Chung B, Carter DW, Ayoung-Chee P, Chiang W, Rushing A, Steinberg S, Foster CS, Schaetzel SM, Price TP, Mandell KA, Ferrigno L, Salzberg M, DeUgarte DA, Kaji AH, Moran GJ, Saltzman D, Alam HB, Park PK, Kao LS, Thompson CM, Self WH, Yu JT, Wiebusch A, Winchell RJ, Clark S, Krishnadasan A, Fannon E, Lavallee DC, Comstock BA, Bizzell B, Heagerty PJ, Kessler LG, Talan DA. PMID: 33017106.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Society of Interventional Radiology Clinical Practice Guideline for Inferior Vena Cava Filters in the Treatment of Patients with Venous Thromboembolic Disease: Developed in collaboration with the American College of Cardiology, American College of Chest Physicians, American College of Surgeons Committee on Trauma, American Heart Association, Society for Vascular Surgery, and Society for Vascular Medicine. J Vasc Interv Radiol. 2020 Oct; 31(10):1529-1544. Kaufman JA, Barnes GD, Chaer RA, Cuschieri J, Eberhardt RT, Johnson MS, Kuo WT, Murin S, Patel S, Rajasekhar A, Weinberg I, Gillespie DL. PMID: 32919823.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Authors' reply: Understanding state-level Medicaid expansion in the context of nationwide data. J Trauma Acute Care Surg. 2020 08; 89(2):e20-e21. PMID: 32301881.
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    11. Splenic artery angioembolization for high-grade splenic injury: Are we wasting money? Am J Surg. 2021 01; 221(1):204-210. Senekjian L, Cuschieri J, Robinson BRH. PMID: 32693942.
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    12. Predictors of mortality, limb loss, and discharge disposition at admission among patients with necrotizing skin and soft tissue infections. J Trauma Acute Care Surg. 2020 07; 89(1):186-191. PMID: 32102045.
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    13. Prospective Validation of a Transcriptomic Metric in Severe Trauma. Ann Surg. 2020 05; 271(5):802-810. PMID: 30688688.
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    14. Proceedings from the Consensus Conference on Trauma Patient-Reported Outcome Measures. J Am Coll Surg. 2020 05; 230(5):819-835. PMID: 32201197.
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    15. Lifting the burden: State Medicaid expansion reduces financial risk for the injured. J Trauma Acute Care Surg. 2020 01; 88(1):51-58. PMID: 31524838.
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    16. Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma. Sci Rep. 2019 09 20; 9(1):13648. PMID: 31541163.
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    17. Ventilator-associated events, not ventilator-associated pneumonia, is associated with higher mortality in trauma patients. J Trauma Acute Care Surg. 2019 08; 87(2):307-314. Meagher AD, Lind M, Senekjian L, Iwuchukwu C, Lynch JB, Cuschieri J, Robinson BRH. PMID: 30939576.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Authors Response to Commentary on our Manuscript. J Trauma Acute Care Surg. 2019 03; 86(3):554-555. PMID: 30444860.
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    19. Trauma Surgeon and Palliative Care Physician Attitudes Regarding Goals-of-Care Delineation for Injured Geriatric Patients. Am J Hosp Palliat Care. 2019 Aug; 36(8):669-674. Cunningham HB, Scielzo SA, Nakonezny PA, Bruns BR, Brasel KJ, Inaba K, Brakenridge SC, Kerby JD, Joseph BA, Mohler MJ, Cuschieri J, Paulk ME, Ekeh AP, Madni TD, Taveras LR, Imran JB, Wolf SE, Phelan HA. PMID: 30614253.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Burn Surgeon and Palliative Care Physician Attitudes Regarding Goals of Care Delineation for Burned Geriatric Patients. J Burn Care Res. 2018 10 23; 39(6):1000-1005. Cunningham HB, Scielzo SA, Nakonezny PA, Bruns BR, Brasel KJ, Inaba K, Brakenridge SC, Kerby JD, Joseph BA, Mohler MJ, Cuschieri J, Paulk ME, Ekeh AP, Madni TD, Taveras LR, Imran JB, Wolf SE, Phelan HA. PMID: 29771351.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Decreased Risk of Delirium With Use of Regional Analgesia in Geriatric Trauma Patients With Multiple Rib Fractures. Ann Surg. 2018 09; 268(3):534-540. PMID: 30048325.
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    22. Unique Uses of Cooling Strategies. Ther Hypothermia Temp Manag. 2018 09; 8(3):126-130. Lyden P, Paul J, Yokobori S, Cuschieri J. PMID: 30096262.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    23. Duration of Respiratory Failure After Trauma Is Not Associated With Increased Long-Term Mortality. Crit Care Med. 2018 08; 46(8):1263-1268. PMID: 29742591.
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    24. Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the Intensive Care Unit: A Stepped-Wedge Cluster Randomized Clinical Trial. JAMA Surg. 2018 05 01; 153(5):464-470. PMID: 29299602.
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    25. Fellowship training in extracorporeal life support: Characterization and educational needs assessment. J Crit Care. 2018 08; 46:159-161. PMID: 29606413.
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    26. Short-Course Antimicrobial Therapy Does Not Increase Treatment Failure Rate in Patients with Intra-Abdominal Infection Involving Fungal Organisms. Surg Infect (Larchmt). 2018 May/Jun; 19(4):376-381. PMID: 29565726.
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    27. A cohort study of blunt cerebrovascular injury screening in children: Are they just little adults? J Trauma Acute Care Surg. 2018 01; 84(1):50-57. PMID: 28640778.
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    28. The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers. Crit Care Med. 2017 Dec; 45(12):1989-1996. PMID: 28837430.
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    29. Novel Method Suggests Global Superiority of Short-Duration Antibiotics for Intra-abdominal Infections. Clin Infect Dis. 2017 Oct 16; 65(9):1577-1579. PMID: 29020201.
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    30. Does Isolation of Enterococcus Affect Outcomes in Intra-Abdominal Infections? Surg Infect (Larchmt). 2017 Nov/Dec; 18(8):879-885. Sanders JM, Tessier JM, Sawyer R, Dellinger EP, Miller PR, Namias N, West MA, Cook CH, O'Neill PJ, Napolitano L, Rattan R, Cuschieri J, Claridge JA, Guidry CA, Askari R, Banton K, Rotstein O, Moore BJ, Duane TM. PMID: 28994635.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    31. Transcranial Doppler Microemboli Monitoring for Stroke Risk Stratification in Blunt Cerebrovascular Injury. Crit Care Med. 2017 Oct; 45(10):e1011-e1017. Bonow RH, Witt CE, Mosher BP, Mossa-Basha M, Vavilala MS, Rivara FP, Cuschieri J, Arbabi S, Chesnut RM. PMID: 28658027.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial. JAMA. 2017 08 22; 318(8):731-740. PMID: 28829877.
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    33. Validation of a Geriatric Trauma Prognosis Calculator: A P.A.L.Li.A.T.E. Consortium Study. J Am Geriatr Soc. 2017 Oct; 65(10):2302-2307. Cook AC, Joseph B, Mohler MJ, Inaba K, Bruns BR, Nakonezny PA, Kerby JD, Brasel KJ, Wolf SE, Cuschieri J, Paulk ME, Rhodes RL, Brakenridge SC, Ekeh AP, Phelan HA. PMID: 28804877.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    34. A comparison of prognosis calculators for geriatric trauma: A Prognostic Assessment of Life and Limitations After Trauma in the Elderly consortium study. J Trauma Acute Care Surg. 2017 07; 83(1):90-96. Madni TD, Ekeh AP, Brakenridge SC, Brasel KJ, Joseph B, Inaba K, Bruns BR, Kerby JD, Cuschieri J, Mohler MJ, Nakonezny PA, Clark A, Imran J, Wolf SE, Paulk ME, Rhodes RL, Phelan HA. PMID: 28422904.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Longer-Duration Antimicrobial Therapy Does Not Prevent Treatment Failure in High-Risk Patients with Complicated Intra-Abdominal Infections. Surg Infect (Larchmt). 2017 Aug/Sep; 18(6):659-663. Hassinger TE, Guidry CA, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Napolitano LM, Namias N, Miller PR, Dellinger EP, Coimbra R, Cocanour CS, Banton KL, Cuschieri J, Popovsky K, Sawyer RG. PMID: 28650745.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    36. Age and Its Impact on Outcomes with Intra-Abdominal Infection. Surg Infect (Larchmt). 2017 Feb/Mar; 18(2):77-82. PMID: 28005468.
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    37. Preventing hospital-acquired venous thromboembolism: Improving patient safety with interdisciplinary teamwork, quality improvement analytics, and data transparency. J Hosp Med. 2016 12; 11 Suppl 2:S38-S43. PMID: 27925422.
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    38. Acute Rehabilitation after Trauma: Does it Really Matter? J Am Coll Surg. 2016 12; 223(6):755-763. PMID: 28193321.
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    39. Patients with Risk Factors for Complications Do Not Require Longer Antimicrobial Therapy for Complicated Intra-Abdominal Infection. Am Surg. 2016 Sep; 82(9):860-6. Rattan R, Allen CJ, Sawyer RG, Mazuski J, Duane TM, Askari R, Banton KL, Claridge JA, Coimbra R, Cuschieri J, Dellinger EP, Evans HL, Guidry CA, Miller PR, O'Neill PJ, Rotstein OD, West MA, Popovsky K, Namias N. PMID: 27670577.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    40. Sex-based differences in the genomic response, innate immunity, organ dysfunction, and clinical outcomes after severe blunt traumatic injury and hemorrhagic shock. J Trauma Acute Care Surg. 2016 09; 81(3):478-85. PMID: 27306446.
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    41. Inclusion of Vancomycin as Part of Broad-Spectrum Coverage Does Not Improve Outcomes in Patients with Intra-Abdominal Infections: A Post Hoc Analysis. Surg Infect (Larchmt). 2016 Dec; 17(6):694-699. Sanders JM, Tessier JM, Sawyer RG, Lipsett PA, Miller PR, Namias N, O'Neill PJ, Dellinger EP, Coimbra R, Guidry CA, Cuschieri J, Banton KL, Cook CH, Moore BJ, Duane TM. PMID: 27483362.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    42. Surgical Management of Clostridium difficile Infection: The Role of Colectomy. Surg Infect (Larchmt). 2016 Jun; 17(3):343-5. PMID: 27003312.
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    43. Patients with Complicated Intra-Abdominal Infection Presenting with Sepsis Do Not Require Longer Duration of Antimicrobial Therapy. J Am Coll Surg. 2016 Apr; 222(4):440-6. Rattan R, Allen CJ, Sawyer RG, Askari R, Banton KL, Claridge JA, Cocanour CS, Coimbra R, Cook CH, Cuschieri J, Dellinger EP, Duane TM, Evans HL, Lipsett PA, Mazuski JE, Miller PR, O'Neill PJ, Rotstein OD, Namias N. PMID: 26920994.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    44. The Role of Lipopolysaccharide Structure in Monocyte Activation and Cytokine Secretion. Shock. 2016 Jan; 45(1):22-7. Plevin RE, Knoll M, McKay M, Arbabi S, Cuschieri J. PMID: 26674452.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    45. Pediatric solid organ injury operative interventions and outcomes at Harborview Medical Center, before and after introduction of a solid organ injury pathway for pediatrics. J Trauma Acute Care Surg. 2015 Aug; 79(2):215-20. PMID: 26218688.
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    46. Prehospital Resuscitation of Traumatic Hemorrhagic Shock with Hypertonic Solutions Worsens Hypocoagulation and Hyperfibrinolysis. Shock. 2015 Jul; 44(1):25-31. Delano MJ, Rizoli SB, Rhind SG, Cuschieri J, Junger W, Baker AJ, Dubick MA, Hoyt DB, Bulger EM. PMID: 25784523.
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    47. Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma. Ann Surg. 2015 May; 261(5):997-1005. Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, . PMID: 24670858.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    48. Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock. Crit Care. 2015 Mar 04; 19:77. PMID: 25880307.
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    49. Evolving beyond the vicious triad: Differential mediation of traumatic coagulopathy by injury, shock, and resuscitation. J Trauma Acute Care Surg. 2015 Mar; 78(3):516-23. Kutcher ME, Howard BM, Sperry JL, Hubbard AE, Decker AL, Cuschieri J, Minei JP, Moore EE, Brownstein BH, Maier RV, Cohen MJ. PMID: 25710421.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    50. Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy. Ann Surg. 2014 Aug; 260(2):378-82. Neal MD, Brown JB, Moore EE, Cuschieri J, Maier RV, Minei JP, Billiar TR, Peitzman AB, Cohen MJ, Sperry JL. PMID: 24424149; PMCID: PMC4096620.
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    51. Pre-hospital aspiration is associated with increased pulmonary complications. Surg Infect (Larchmt). 2015 Apr; 16(2):159-64. PMID: 24896218.
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    52. A better understanding of why murine models of trauma do not recapitulate the human syndrome. Crit Care Med. 2014 Jun; 42(6):1406-13. PMID: 24413577.
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    53. Delayed topical p38 MAPK inhibition attenuates full-thickness burn wound inflammatory signaling. J Burn Care Res. 2014 Mar-Apr; 35(2):e83-92. PMID: 23666384.
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    54. Differences in end-of-life care in the ICU across patients cared for by medicine, surgery, neurology, and neurosurgery physicians. Chest. 2014 Feb; 145(2):313-321. PMID: 24114410.
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    55. Determining a core curriculum in surgical infections for fellowship training in acute care surgery using the Delphi technique. Surg Infect (Larchmt). 2013 Dec; 14(6):547-53. PMID: 24446894.
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    56. Upper extremity deep vein thrombosis in hospitalized patients: a descriptive study. J Hosp Med. 2014 Jan; 9(1):48-53. PMID: 24281984.
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    57. Prehospital hypertonic saline resuscitation attenuates the activation and promotes apoptosis of neutrophils in patients with severe traumatic brain injury. Shock. 2013 Nov; 40(5):366-74. Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Baker AJ, Shek PN, Hoyt DB, Bulger EM. PMID: 24088993.
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    58. Comparing clinical predictors of deep venous thrombosis versus pulmonary embolus after severe injury: a new paradigm for posttraumatic venous thromboembolism? J Trauma Acute Care Surg. 2013 May; 74(5):1231-7; discussion 1237-8. Brakenridge SC, Henley SS, Kashner TM, Golden RM, Paik DH, Phelan HA, Cohen MJ, Sperry JL, Moore EE, Minei JP, Maier RV, Cuschieri J. PMID: 23609272; PMCID: PMC3716365.
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    59. Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients. Crit Care Med. 2013 May; 41(5):1175-85. PMID: 23388514.
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    60. Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis. J Trauma Acute Care Surg. 2013 May; 74(5):1207-12; discussion 1212-4. Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, . PMID: 23609269.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    61. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3507-12. Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG, . PMID: 23401516.
      View in: PubMed   Mentions: 990     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    62. Antiplatelet therapy is associated with decreased transfusion-associated risk of lung dysfunction, multiple organ failure, and mortality in trauma patients. Crit Care Med. 2013 Feb; 41(2):399-404. Harr JN, Moore EE, Johnson J, Chin TL, Wohlauer MV, Maier R, Cuschieri J, Sperry J, Banerjee A, Silliman CC, Sauaia A. PMID: 23263579.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    63. Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix. J Trauma Acute Care Surg. 2012 Dec; 73(6):1395-400. Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, . PMID: 23064602.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    64. Who should we feed? Western Trauma Association multi-institutional study of enteral nutrition in the open abdomen after injury. J Trauma Acute Care Surg. 2012 Dec; 73(6):1380-7; discussion 1387-8. Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Nirula R, Millar D, Cohen MJ, Kutcher ME, Haan J, MacNew HG, Ochsner G, Rowell SE, Truitt MS, Moore FO, Pieracci FM, Kaups KL, . PMID: 22835999.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    65. Resuscitation of traumatic hemorrhagic shock patients with hypertonic saline-without dextran-inhibits neutrophil and endothelial cell activation. Shock. 2012 Oct; 38(4):341-50. Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Shiu MY, Baker AJ, Li L, Shek PN, Hoyt DB, Bulger EM. PMID: 22777113.
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    66. Acute respiratory distress syndrome after trauma: development and validation of a predictive model. Crit Care Med. 2012 Aug; 40(8):2295-303. PMID: 22809905.
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    67. Hypothermia in massive transfusion: have we been paying enough attention to it? J Trauma Acute Care Surg. 2012 Aug; 73(2):486-91. PMID: 23019675.
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    68. The role and value of surgical critical care, an essential component of Acute Care Surgery, in the Affordable Care Act: a report from the Critical Care Committee and Board of Managers of the American Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2012 Jul; 73(1):20-6. Frankel HL, Butler KL, Cuschieri J, Friese RS, Huynh T, Mohr AM, Schinco MA, Napolitano LM, Britt LD, Coimbra R, Croce MA, Davis JW, Jurkovich GJ, Moore EE, Morris JA, Peitzman AB, Pruitt BA, Rozycki GS, Scalea TM, Meredith JW. PMID: 22743368.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    69. Active surveillance cultures of methicillin-resistant Staphylococcus aureus as a tool to predict methicillin-resistant S. aureus ventilator-associated pneumonia. Crit Care Med. 2012 May; 40(5):1437-42. PMID: 22511127.
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    70. Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg. 2012 May; 255(5):993-9. Cuschieri J, Johnson JL, Sperry J, West MA, Moore EE, Minei JP, Bankey PE, Nathens AB, Cuenca AG, Efron PA, Hennessy L, Xiao W, Mindrinos MN, McDonald-Smith GP, Mason PH, Billiar TR, Schoenfeld DA, Warren HS, Cobb JP, Moldawer LL, Davis RW, Maier RV, Tompkins RG, . PMID: 22470077.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    71. The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock. Crit Care Med. 2012 Apr; 40(4):1129-35. Minei JP, Cuschieri J, Sperry J, Moore EE, West MA, Harbrecht BG, O'Keefe GE, Cohen MJ, Moldawer LL, Tompkins RG, Maier RV, . PMID: 22020243.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    72. Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way. J Trauma Acute Care Surg. 2012 Apr; 72(4):892-8. Neal MD, Hoffman MK, Cuschieri J, Minei JP, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Cohen MJ, Sperry JL. PMID: 22491601; PMCID: PMC3347772.
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    73. Obese patients show a depressed cytokine profile following severe blunt injury. Shock. 2012 Mar; 37(3):253-6. PMID: 22266966.
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    74. Ventilator-associated pneumonia: bacteremia and death after traumatic injury. J Trauma Acute Care Surg. 2012 Mar; 72(3):713-9. PMID: 22491559.
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    75. Changes in massive transfusion over time: an early shift in the right direction? J Trauma Acute Care Surg. 2012 Jan; 72(1):106-11. Kautza BC, Cohen MJ, Cuschieri J, Minei JP, Brackenridge SC, Maier RV, Harbrecht BG, Moore EE, Billiar TR, Peitzman AB, Sperry JL. PMID: 22310123; PMCID: PMC3276234.
      View in: PubMed   Mentions:
    76. A genomic storm in critically injured humans. J Exp Med. 2011 Dec 19; 208(13):2581-90. Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker HV, Finnerty CC, Jeschke MG, López MC, Klein MB, Gamelli RL, Gibran NS, Arnoldo B, Xu W, Zhang Y, Calvano SE, McDonald-Smith GP, Schoenfeld DA, Storey JD, Cobb JP, Warren HS, Moldawer LL, Herndon DN, Lowry SF, Maier RV, Davis RW, Tompkins RG, . PMID: 22110166.
      View in: PubMed   Mentions: 330     Fields:    Translation:HumansCellsCTClinical Trials
    77. Increased neutrophil adenosine a3 receptor expression is associated with hemorrhagic shock and injury severity in trauma patients. Shock. 2011 Nov; 36(5):435-9. PMID: 21841534.
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    78. Pre-hospital intubation factors and pneumonia in trauma patients. Surg Infect (Larchmt). 2011 Oct; 12(5):339-44. PMID: 21933010.
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    79. Early blood product and crystalloid volume resuscitation: risk association with multiple organ dysfunction after severe blunt traumatic injury. J Trauma. 2011 Aug; 71(2):299-305. Brakenridge SC, Phelan HA, Henley SS, Golden RM, Kashner TM, Eastman AE, Sperry JL, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Minei JP, . PMID: 21825930.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    80. Clinical outcomes of linezolid vs vancomycin in methicillin-resistant Staphylococcus aureus ventilator-associated pneumonia: retrospective analysis. J Intensive Care Med. 2011 Nov-Dec; 26(6):385-91. PMID: 21606058.
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    81. Steroids after severe injury: many unanswered questions. JAMA. 2011 Mar 23; 305(12):1242-3. PMID: 21427379.
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    82. Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury. J Trauma. 2011 Feb; 70(2):292-8. Edmonds RD, Cuschieri J, Minei JP, Rosengart MR, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Sperry JL. PMID: 21307724.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    83. Sew it up! A Western Trauma Association multi-institutional study of enteric injury management in the postinjury open abdomen. J Trauma. 2011 Feb; 70(2):273-7. Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Crowell K, Nirula R, Haan J, Rowell SE, Kato CM, MacNew H, Ochsner MG, Harrison PB, Fusco C, Sauaia A, Kaups KL. PMID: 21307721.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    84. The association between the transfusion of older blood and outcomes after trauma. Shock. 2011 Jan; 35(1):3-8. PMID: 20823694.
      View in: PubMed   Mentions:
    85. Identification and interpretation of longitudinal gene expression changes in trauma. PLoS One. 2010 Dec 20; 5(12):e14380. Rajicic N, Cuschieri J, Finkelstein DM, Miller-Graziano CL, Hayden D, Moldawer LL, Moore E, O'Keefe G, Pelik K, Warren HS, Schoenfeld DA. PMID: 21187951.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    86. Timing of intubation and ventilator-associated pneumonia following injury. Arch Surg. 2010 Nov; 145(11):1041-6. PMID: 21079091.
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    87. Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure. Shock. 2010 Oct; 34(4):346-51. Cuschieri J, Bulger E, Schaeffer V, Sakr S, Nathens AB, Hennessy L, Minei J, Moore EE, O'Keefe G, Sperry J, Remick D, Tompkins R, Maier RV. PMID: 20844410.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    88. Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline. J Surg Res. 2011 Dec; 171(2):769-76. PMID: 20828737.
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    89. Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):9923-8. Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'Keefe G. PMID: 20479259.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    90. Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patients. Arch Surg. 2010 Mar; 145(3):240-6. PMID: 20231624.
      View in: PubMed   Mentions:
    91. Traditional resuscitative practices fail to resolve metabolic acidosis in morbidly obese patients after severe blunt trauma. J Trauma. 2010 Feb; 68(2):317-30. PMID: 20154544.
      View in: PubMed   Mentions:
    92. Differences in outcome between obese and nonobese patients following severe blunt trauma are not consistent with an early inflammatory genomic response. Crit Care Med. 2010 Jan; 38(1):51-8. PMID: 19661803.
      View in: PubMed   Mentions:
    93. Oxidant alterations in CD16 expression are cytoskeletal induced. Shock. 2009 Dec; 32(6):572-7. PMID: 19333136.
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    94. Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury. Ann Surg. 2009 Oct; 250(4):531-9. Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV. PMID: 19730236.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    95. Inflammation and the host response to injury, a Large-Scale Collaborative Project: patient-oriented research core standard operating procedures for clinical care IX. Definitions for complications of clinical care of critically injured patients. J Trauma. 2009 Aug; 67(2):384-8. Evans HL, Cuschieri J, Moore EE, Shapiro MB, Nathens AB, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, West MA. PMID: 19667895; PMCID: PMC4001934.
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    96. Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma. 2009 Aug; 67(2):221-7; discussion 228-30. Watson GA, Sperry JL, Rosengart MR, Minei JP, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Billiar TR, Peitzman AB. PMID: 19667872.
      View in: PubMed   Mentions: 70     Fields:    Translation:Humans
    97. Single-dose etomidate for rapid sequence intubation may impact outcome after severe injury. J Trauma. 2009 Jul; 67(1):45-50. Warner KJ, Cuschieri J, Jurkovich GJ, Bulger EM. PMID: 19590307.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    98. A genomic score prognostic of outcome in trauma patients. Mol Med. 2009 Jul-Aug; 15(7-8):220-7. Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG. PMID: 19593405.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    99. Characterization of persistent hyperglycemia: what does it mean postinjury? J Trauma. 2009 Apr; 66(4):1076-82. Sperry JL, Frankel HL, Nathens AB, O'keefe GE, Cuschieri J, Moore EE, Maier RV, Minei JP. PMID: 19359917.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    100. Assessment of functional limitation after necrotizing soft tissue infection. J Burn Care Res. 2009 Mar-Apr; 30(2):301-6. PMID: 19165118.
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    101. The utility of early end-tidal capnography in monitoring ventilation status after severe injury. J Trauma. 2009 Jan; 66(1):26-31. Warner KJ, Cuschieri J, Garland B, Carlbom D, Baker D, Copass MK, Jurkovich GJ, Bulger EM. PMID: 19131802.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    102. The evolution of the diagnostic work-up for stab wounds to the back and flank. Injury. 2009 Jan; 40(1):48-53. Pham TN, Heinberg E, Cuschieri J, Bulger EM, O'Keefe GE, Gross JA, Jurkovich GJ. PMID: 19117560.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    103. Necrotizing soft tissue infection. Surg Infect (Larchmt). 2008 Dec; 9(6):559-62. PMID: 19216666.
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    104. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VIII--Nutritional support of the trauma patient. J Trauma. 2008 Dec; 65(6):1520-8. O'Keefe GE, Shelton M, Cuschieri J, Moore EE, Lowry SF, Harbrecht BG, Maier RV. PMID: 19077652.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    105. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VII--Guidelines for antibiotic administration in severely injured patients. J Trauma. 2008 Dec; 65(6):1511-9. West MA, Moore EE, Shapiro MB, Nathens AB, Cuschieri J, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV. PMID: 19077651.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    106. An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma. 2008 Nov; 65(5):986-93. Sperry JL, Ochoa JB, Gunn SR, Alarcon LH, Minei JP, Cuschieri J, Rosengart MR, Maier RV, Billiar TR, Peitzman AB, Moore EE. PMID: 19001962.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCTClinical Trials
    107. Inflammation and the host response to injury a large-scale collaborative project: patient-oriented research core standard operating procedure for clinical care X. Guidelines for venous thromboembolism prophylaxis in the trauma patient. J Trauma. 2008 Oct; 65(4):944-50. Cuschieri J, Freeman B, O'Keefe G, Harbrecht BG, Bankey P, Johnson JL, Minei JP, Sperry J, West M, Nathens A, Moore EE, Maier RV. PMID: 18849816; PMCID: PMC4004057.
      View in: PubMed   Mentions:
    108. Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcomes Assessment Program. Ann Surg. 2008 Oct; 248(4):557-63. Cuschieri J, Florence M, Flum DR, Jurkovich GJ, Lin P, Steele SR, Symons RG, Thirlby R. PMID: 18936568.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    109. Effect of immediate enteral feeding on trauma patients with an open abdomen: protection from nosocomial infections. J Am Coll Surg. 2008 Nov; 207(5):690-7. PMID: 18954781.
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    110. Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients. J Am Coll Surg. 2008 Oct; 207(4):459-67. Sena MJ, Utter GH, Cuschieri J, Maier RV, Tompkins RG, Harbrecht BG, Moore EE, O'Keefe GE. PMID: 18926446.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    111. Male gender is associated with excessive IL-6 expression following severe injury. J Trauma. 2008 Mar; 64(3):572-8; discussion 578-9. Sperry JL, Friese RS, Frankel HL, West MA, Cuschieri J, Moore EE, Harbrecht BG, Peitzman AB, Billiar TR, Maier RV, Remick DG, Minei JP. PMID: 18332795.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    112. Emergency department ventilation effects outcome in severe traumatic brain injury. J Trauma. 2008 Feb; 64(2):341-7. Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM. PMID: 18301196.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    113. Insulin regulates macrophage activation through activin A. Shock. 2008 Feb; 29(2):285-90. PMID: 17693932.
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    114. Mechanistic analysis of macrophage response to IRAK-1 gene knockdown by a smart polymer-antisense oligonucleotide therapeutic. J Biomater Sci Polym Ed. 2008; 19(10):1333-46. PMID: 18854126.
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    115. Oxidative stress, lipid rafts, and macrophage reprogramming. Antioxid Redox Signal. 2007 Sep; 9(9):1485-97. PMID: 17638545.
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    116. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core-standard operating procedures for clinical care: VI. Blood glucose control in the critically ill trauma patient. J Trauma. 2007 Sep; 63(3):703-8. Harbrecht BG, Minei JP, Shapiro MB, Nathens AB, Moore EE, West MA, Bankey PE, Cuschieri J, Johnson JL, Maier RV. PMID: 18073622.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    117. The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway. Shock. 2007 Jun; 27(6):623-30. PMID: 17505301.
      View in: PubMed   Mentions:
    118. The impact of prehospital ventilation on outcome after severe traumatic brain injury. J Trauma. 2007 Jun; 62(6):1330-6; discussion 1336-8. Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM. PMID: 17563643.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    119. Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock. Ann Surg. 2007 Apr; 245(4):635-41. PMID: 17414614.
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    120. The practice of venous thromboembolism prophylaxis in the major trauma patient. J Trauma. 2007 Mar; 62(3):557-62; discussion 562-3. Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV. PMID: 17414328.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    121. Acid sphingomyelinase is required for lipid Raft TLR4 complex formation. Surg Infect (Larchmt). 2007 Feb; 8(1):91-106. PMID: 17381401.
      View in: PubMed   Mentions:
    122. Vitamin E inhibits endotoxin-mediated transport of phosphatases to lipid rafts. Shock. 2007 Jan; 27(1):19-24. PMID: 17172975.
      View in: PubMed   Mentions:
    123. Surgical management of acute necrotizing lung infections. Can Respir J. 2006 Oct; 13(7):369-73. PMID: 17036090.
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    124. Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: a condition reversed by PKC activation. J Leukoc Biol. 2006 Dec; 80(6):1289-97. PMID: 16959900.
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    125. Phosphatidylcholine-specific phospholipase C (PC-PLC) is required for LPS-mediated macrophage activation through CD14. J Leukoc Biol. 2006 Aug; 80(2):407-14. PMID: 16754725.
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    126. The modeling of the radiation and response green's function of a fluid-loaded cylindrical shell with an external compliant layer. J Acoust Soc Am. 2006 Apr; 119(4):2150-69. PMID: 16642830.
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    127. Mitogen-activated protein kinase (MAPK). Crit Care Med. 2005 Dec; 33(12 Suppl):S417-9. PMID: 16340409.
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    128. Oxidative-induced calcium mobilization is dependent on annexin VI release from lipid rafts. Surgery. 2005 Aug; 138(2):158-64. PMID: 16153422.
      View in: PubMed   Mentions:
    129. Central venous-arterial carbon dioxide difference as an indicator of cardiac index. Intensive Care Med. 2005 Jun; 31(6):818-22. PMID: 15803301.
      View in: PubMed   Mentions:
    130. The role of repeat angiography in the management of pelvic fractures. J Trauma. 2005 Feb; 58(2):227-31. PMID: 15706180.
      View in: PubMed   Mentions:
    131. Calcium/calmodulin-dependent kinase II is required for platelet-activating factor priming. Shock. 2005 Feb; 23(2):99-106. PMID: 15665723.
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    132. PKC-zeta is essential for endotoxin-induced macrophage activation. J Surg Res. 2004 Sep; 121(1):76-83. PMID: 15313379.
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    133. Implications of lipid raft disintegration: enhanced anti-inflammatory macrophage phenotype. Surgery. 2004 Aug; 136(2):169-75. PMID: 15300176.
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    134. Implications of proteasome inhibition: an enhanced macrophage phenotype. Cell Immunol. 2004 Feb; 227(2):140-7. PMID: 15135296.
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    135. Modulation of macrophage responsiveness to lipopolysaccharide by IRAK-1 manipulation. Shock. 2004 Feb; 21(2):182-8. PMID: 14752294.
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    136. NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation. Surgery. 2003 Aug; 134(2):378-83. PMID: 12947344.
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    137. Modulation of endotoxin-induced endothelial function by calcium/calmodulin-dependent protein kinase. Shock. 2003 Aug; 20(2):176-82. PMID: 12865664.
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    138. Platelet-activating factor acetylhydrolase inhibits alveolar macrophage activation in vivo. Shock. 2003 Jul; 20(1):17-22. PMID: 12813363.
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    139. Modulation of endotoxin-induced endothelial activity by microtubule depolymerization. J Trauma. 2003 Jan; 54(1):104-12; discussion 112-3. PMID: 12544905.
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    140. Platelet-activating factor priming of inflammatory cell activity requires cellular adherence. Surgery. 2002 Aug; 132(2):157-66. PMID: 12219006.
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    141. Slow channel calcium inhibition blocks proinflammatory gene signaling and reduces macrophage responsiveness. J Trauma. 2002 Mar; 52(3):434-42. PMID: 11901316.
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    142. Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin. J Immunol. 2002 Feb 01; 168(3):1389-96. PMID: 11801680.
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