Joseph Cuschieri, MD, FACS

Title(s)Professor, Surgery
SchoolSchool of Medicine
Address1001 Potrero Avenue, #3A25
San Francisco CA 94110
Phone--
ORCID ORCID Icon0000-0003-1456-6841 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of MichiganBS6/1990Biochemistry
    Wayne State University School of MedicineMD6/1994Medicine
    Henry Ford Hospital Medical Center6/1998Surgical Critical Care
    Henry Ford Hospital Medical Center6/2000General Surgery
    University of Washington6/2002T32 Trauma/Burn/Inflammation
    University of California, San Francisco, CA09/2021Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    Surgical Infection Society2006Joseph Sussman Memorial Award
    Castle Connelly Inc.2006  - 2021Castle Connelly Top Doctors
    Centers of Disease Control2015CDC HA-VTE Prevention Challenge Champion
    University of Washington School of Medicine2019John K. Stevenson Faculty Teaching Award in Surgery

    Collapse Overview 
    Collapse Overview
    Joseph Cuschieri M.D. earned his Bachelor of Science Degree in Biochemistry from the University of Michigan, and his Medical Degree from Wayne State University School of Medicine. He completed his general surgery residence and surgical critical care fellowship at Henry Ford Hospital in Detroit, Michigan. Upon completion of his clinical training, he completed a 2-year NIH T32 Fellowship in the field of Trauma/Burn/Inflammation.

    Dr. Cuschieri is certified by the American Board of Surgery in General Surgery with subspecialty certification in Surgical Critical Care.

    Upon completion of his fellowship in 2002, Dr. Cuschieri joined the faculty at the University of Cincinnati School of Medicine. After a couple of years he left Cincinnati and returned to Seattle, joining the faculty at the University of Washington School of Medicine where he served as the Medical Director of Surgical Critical Care, Interim Associate Medical Director of Critical Care, Associate Medical Director of Surgical Services, and Program Director of Surgical Critical Care. Dr. Cuschieri left Washington and came to UCSF in 2021 to join the faculty in the Department of Surgery as Professor and Trauma Medical Director at the Zuckerberg San Francisco General Hospital and Trauma Center.

    Dr. Cuschieri currently serves as Principal Investigator, Co-Principle investigator, or Co-Investigator on 3 federally funded grants and has authored or co-authored over 170 peer-reviewed articles and more than 10 book chapters. His national service includes active participation in major trauma, critical care, and surgical societies including the American Association for the Surgery of Trauma and the Society of Surgical Critical Care Program Directors. He also serves on the Editorial Board for the Journal of Trauma and Acute Care Surgery.

    Collapse Research 
    Collapse Research Activities and Funding
    Surgery Research Training Program
    NIH T32GM121290Jul 1, 2017 - Jun 30, 2022
    Role: Co-Investigator
    Validation of a Genomics Based Prognostic in Severe Trauma
    NIH R01GM104481Jun 1, 2013 - Apr 30, 2017
    Role: Co-Investigator
    Bedside Genomics in Severe Trauma
    NIH R01GM101401Sep 25, 2012 - Aug 31, 2014
    Role: Co-Investigator
    Planning a Multi-Center Trial of Interferon-gamma in Trauma Patients
    NIH R34GM102666Sep 1, 2012 - Aug 31, 2014
    Role: Co-Investigator
    A Randomzied Phase II Trial of CMV Prevention in Acute Lung Injury
    NIH U01HL102547Jun 1, 2010 - Dec 31, 2016
    Role: Co-Investigator
    SIS multicenter study of duration of antibiotics for intraabdominal infection
    NIH R01GM081510Sep 11, 2007 - Aug 31, 2014
    Role: Co-Investigator
    TRAUMA &SEPSIS INDUCED CHANGES IN IMMUNE CELL MEMBRANE RECEPTOR TRAFFICKING
    NIH R01GM078054Sep 1, 2007 - Jun 30, 2013
    Role: Principal Investigator
    Hypertonic Modulation of Inflammation following Injury
    NIH R01GM076101Jun 11, 2007 - Nov 30, 2012
    Role: Co-Investigator
    Inflammation and the Host Responses to Injury
    NIH U54GM062119Sep 1, 2000 - Aug 31, 2013
    Role: Co-Investigator
    POSTDOCTORAL TRAINING
    NIH T32GM007037Jul 1, 1975 - Jun 30, 2015
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Insights from CTTACC: immune system reset by cellular therapies for chronic illness after trauma, infection, and burn. Cytotherapy. 2024 Feb 24. Bertram K, Cox C, Alam H, Lowell C, Cuschieri J, Parekkadan B, Pati S. PMID: 38506768.
      View in: PubMed   Mentions:    Fields:    
    2. Effect of Aspirin Versus Low-Molecular-Weight Heparin Thromboprophylaxis on Medication Satisfaction and Out-of-Pocket Costs: A Secondary Analysis of a Randomized Clinical Trial. J Bone Joint Surg Am. 2024 Feb 21. O'Hara NN, Frey KP, Stein DM, Levy JF, Slobogean GP, Castillo R, Firoozabadi R, Karunakar MA, Gary JL, Obremskey WT, Seymour RB, Cuschieri J, Mullins CD, O'Toole RV, METRC. PMID: 38381842.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Risk-stratified thromboprophylaxis effects of aspirin versus low-molecular-weight heparin in orthopaedic trauma patients: a secondary analysis of the PREVENT CLOT trial. J Trauma Acute Care Surg. 2023 Dec 08. O'Hara NN, O'Toole RV, Frey KP, Castillo RC, Cuschieri J, Haut ER, Slobogean GP, Firoozabadi R, Christmas A, Obremskey WT, Carlini AR, Gaski G, Kutcher ME, Marvel D, Stein DM, Major Extremity Trauma Research Consortium (METRC). PMID: 38079260.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Screening for Intimate Partner Violence in Trauma: Results of a Quality Improvement Project. J Surg Res. 2024 Mar; 295:376-384. Decker H, Schwab M, Shao S, Kaki D, Melhado C, Cuschieri J, Bongiovanni T. PMID: 38064979.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. The injured monocyte: The link to chronic critical illness and mortality following injury. J Trauma Acute Care Surg. 2024 Feb 01; 96(2):195-202. Cuschieri J, Kornblith L, Pati S, Piliponsky A. PMID: 37880827.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Trial Participation and Outcomes Among English-Speaking and Spanish-Speaking Patients With Appendicitis Randomized to Antibiotics: A Secondary Analysis of the CODA Randomized Clinical Trial. JAMA Surg. 2023 09 01; 158(9):901-908. Serrano E, Voldal EC, Machado-Aranda D, DeUgarte DA, Kao L, Drake T, Winchell R, Cuschieri J, Krishnadasan A, Talan DA, Siparsky N, Ayoung-Chee P, Self WH, McGonagill P, Mandell KA, Liang MK, Dodwad SJ, Thompson CM, Padilla RM, Fleischman R, Price TP, Jones A, Bernardi K, Garcia L, Evans HL, Sanchez SE, Odom S, Comstock BA, Heagerty PJ, Lawrence SO, Monsell SE, Fannon EEC, Kessler LG, Flum DR, Davidson GH, Writing Group for the CODA Collaborative. PMID: 37379001; PMCID: PMC10308294.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Organ donation in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surg Acute Care Open. 2023; 8(1):e001107. Seshadri A, Cuschieri J, Kaups KL, Knowlton LM, Kutcher ME, Pathak A, Rappold J, Rinderknecht T, Stein DM, Young J, Michetti CP. PMID: 37205276; PMCID: PMC10186482.
      View in: PubMed   Mentions:
    8. Developing a National Trauma Research Action Plan: Results from the long-term outcomes research gap Delphi survey. J Trauma Acute Care Surg. 2022 Dec 01; 93(6):854-862. Herrera-Escobar JP, Reidy E, Phuong J, Brasel KJ, Cuschieri J, Fallat M, Potter BK, Price MA, Bulger EM, Haider AH, Bonne S, Brasel KJ, Cuschieri J, de Roon-Cassini T, Dicker RA, Fallat M, Ficke JR, Gabbe B, Gibran NS, Heinemann AW, Ho V, Kao LS, Kellam JF, Kurowski BG, Levy-Carrick NC, Livingston D, Mandell SP, Manley GT, Michetti CP, Miller AN, Newcomb A, Okonkwo D, Potter BK, Seamon M, Stein D, Wagner AK, Whyte J, Yonclas P, Zatzick D, Zielinski MD, NTRAP Long-term Outcomes Panel. PMID: 35972140.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Alcohol Intoxication Is Associated With Bladder Injury and Bladder Surgical Repair in Patients Sustaining Motor Vehicle Collisions. J Urol. 2022 11; 208(5):1090-1097. Lui JL, Hakam N, Shaw NM, Cuschieri J, Abbasi B, Breyer BN. PMID: 35917522.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Management of Decompensated Cirrhosis in the Surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document. Trauma Surg Acute Care Open. 2022; 7(1):e000936. Seshadri A, Appelbaum R, Carmichael SP, Cuschieri J, Hoth J, Kaups KL, Kodadek L, Kutcher ME, Pathak A, Rappold J, Rudnick SR, Michetti CP. PMID: 35991906; PMCID: PMC9345092.
      View in: PubMed   Mentions: 1  
    11. Perception of Treatment Success and Impact on Function with Antibiotics or Appendectomy for Appendicitis: A Randomized Clinical Trial with an Observational Cohort. Ann Surg. 2023 06 01; 277(6):886-893. Thompson CM, Voldal EC, Davidson GH, Sanchez SE, Ayoung-Chee P, Victory J, Guiden M, Bizzell B, Glaser J, Hults C, Price TP, Siparsky N, Ohe K, Mandell KA, DeUgarte DA, Kaji AH, Uribe L, Kao LS, Mueck KM, Farjah F, Self WH, Clark S, Drake FT, Fischkoff K, Minko E, Cuschieri J, Faine B, Skeete DA, Dhanani N, Liang MK, Krishnadasan A, Talan DA, Fannon E, Kessler LG, Comstock BA, Heagerty PJ, Monsell SE, Lawrence SO, Flum DR, Lavallee DC, Writing Group for the CODA Collaborative. PMID: 35815898; PMCID: PMC10174100.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Analysis of Outcomes Associated With Outpatient Management of Nonoperatively Treated Patients With Appendicitis. JAMA Netw Open. 2022 07 01; 5(7):e2220039. Writing Group for the CODA Collaborative, Talan DA, Moran GJ, Krishnadasan A, Monsell SE, Faine BA, Uribe L, Kaji AH, DeUgarte DA, Self WH, Shapiro NI, Cuschieri J, Glaser J, Park PK, Price TP, Siparsky N, Sanchez SE, Machado-Aranda DA, Victory J, Ayoung-Chee P, Chiang W, Corsa J, Evans HL, Ferrigno L, Garcia L, Hatch Q, Horton MD, Johnson J, Jones A, Kao LS, Kelly A, Kim D, Kutcher ME, Liang MK, Maghami N, McGrane K, Minko E, Mohr C, Neufeld M, Patton JH, Rog C, Rushing A, Sabbatini AK, Salzberg M, Thompson CM, Tichter A, Wisler J, Bizzell B, Fannon E, Lawrence SO, Voldal EC, Lavallee DC, Comstock BA, Heagerty PJ, Davidson GH, Flum DR, Kessler LG. PMID: 35796152; PMCID: PMC9250049.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Self-selection vs Randomized Assignment of Treatment for Appendicitis. JAMA Surg. 2022 07 01; 157(7):598-608. Writing Group for the CODA Collaborative, Davidson GH, Monsell SE, Evans H, Voldal EC, Fannon E, Lawrence SO, Krishnadasan A, Talan DA, Bizzell B, Heagerty PJ, Comstock BA, Lavallee DC, Villegas C, Winchell R, Thompson CM, Self WH, Kao LS, Dodwad SJ, Sabbatini AK, Droullard D, Machado-Aranda D, Gibbons MM, Kaji AH, DeUgarte DA, Ferrigno L, Salzberg M, Mandell KA, Siparsky N, Price TP, Raman A, Corsa J, Wisler J, Ayoung-Chee P, Victory J, Jones A, Kutcher M, McGrane K, Holihan J, Liang MK, Cuschieri J, Johnson J, Fischkoff K, Drake FT, Sanchez SE, Odom SR, Kessler LG, Flum DR. PMID: 35612859; PMCID: PMC9134042.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Postinjury platelet aggregation and venous thromboembolism. J Trauma Acute Care Surg. 2022 11 01; 93(5):604-612. Matthay ZA, Hellmann ZJ, Nunez-Garcia B, Fields AT, Cuschieri J, Neal MD, Berger JS, Luttrell-Williams E, Knudson MM, Cohen MJ, Callcut RA, Kornblith LZ. PMID: 35444156; PMCID: PMC9585095.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Developing a National Trauma Research Action Plan: Results from the acute resuscitation, initial patient evaluation, imaging, and management research gap Delphi survey. J Trauma Acute Care Surg. 2022 08 01; 93(2):200-208. Costantini TW, Galante JM, Braverman MA, Phuong J, Price MA, Cuschieri J, Godat LN, Holcomb JB, Coimbra R, Bulger EM, NTRAP Acute Resuscitation Panel. PMID: 35444148.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Nonoperative Management in Blunt Splenic Trauma: Can Shock Index Predict Failure? J Surg Res. 2022 08; 276:340-346. Senekjian L, Robinson BRH, Meagher AD, Gross JA, Maier RV, Bulger EM, Arbabi S, Cuschieri J. PMID: 35427912.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Patient Factors Associated With Appendectomy Within 30 Days of Initiating Antibiotic Treatment for Appendicitis. JAMA Surg. 2022 Mar 01; 157(3):e216900. Writing Group for the CODA Collaborative, Monsell SE, Voldal EC, Davidson GH, Fischkoff K, Coleman N, Bizzell B, Price T, Narayan M, Siparsky N, Thompson CM, Ayoung-Chee P, Odom SR, Sanchez S, Drake FT, Johnson J, Cuschieri J, Evans HL, Liang MK, McGrane K, Hatch Q, Victory J, Wisler J, Salzberg M, Ferrigno L, Kaji A, DeUgarte DA, Gibbons MM, Alam HB, Scott J, Kao LS, Self WH, Winchell RJ, Villegas CM, Talan DA, Kessler LG, Lavallee DC, Krishnadasan A, Lawrence SO, Comstock B, Fannon E, Flum DR, Heagerty PJ. PMID: 35019975; PMCID: PMC8756360.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    18. A new trauma frontier: Exploratory pilot study of platelet transcriptomics in trauma patients. J Trauma Acute Care Surg. 2022 02 01; 92(2):313-322. Fields AT, Lee MC, Mayer F, Santos YA, Bainton CMV, Matthay ZA, Callcut RA, Mayer N, Cuschieri J, Kober KM, Bainton RJ, Kornblith LZ. PMID: 34738997; PMCID: PMC8781218.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    19. Utility and Outcome of Angioembolization for High-Grade Renal Trauma Management in a Large Hospital-Based Trauma Registry. J Urol. 2022 05; 207(5):1077-1085. Hakam N, Amend GM, Nabavizadeh B, Allen IE, Shaw NM, Cuschieri J, Wilson MW, Stein DM, Breyer BN. PMID: 34981946.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Respiratory events after intensive care unit discharge in trauma patients: Epidemiology, outcomes, and risk factors. J Trauma Acute Care Surg. 2022 01 01; 92(1):28-37. Rosen JE, Bulger EM, Cuschieri J. PMID: 34284468; PMCID: PMC8692327.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score. Br J Surg. 2021 Nov 11; 108(11):1274-1292. COVIDSurg Collaborative . PMID: 34227657; PMCID: PMC8344569.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    22. Antibiotics versus Appendectomy for Acute Appendicitis - Longer-Term Outcomes. N Engl J Med. 2021 12 16; 385(25):2395-2397. CODA Collaborative, Davidson GH, Flum DR, Monsell SE, Kao LS, Voldal EC, Heagerty PJ, Fannon E, Lavallee DC, Bizzell B, Lawrence SO, Comstock BA, Krishnadasan A, Winchell RJ, Self WH, Thompson CM, Farjah F, Park PK, Alam HB, Saltzman D, Moran GJ, Kaji AH, DeUgarte DA, Salzberg M, Ferrigno L, Mandell KA, Price TP, Siparsky N, Glaser J, Ayoung-Chee P, Chiang W, Victory J, Chung B, Carter DW, Kutcher ME, Jones A, Holihan J, Liang MK, Faine BA, Cuschieri J, Evans HL, Johnson J, Patton JH, Coleman N, Fischkoff K, Drake FT, Sanchez SE, Parsons C, Odom SR, Kessler LG, Talan DA. PMID: 34694761.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Chronic critical illness after hypothermia in trauma patients. Trauma Surg Acute Care Open. 2021; 6(1):e000747. Miranda D, Maine R, Cook M, Brakenridge S, Moldawer L, Arbabi S, O'Keefe G, Robinson B, Bulger EM, Maier R, Cuschieri J. PMID: 34423134; PMCID: PMC8323397.
      View in: PubMed   Mentions: 1  
    24. Multi-center validation of the Bowel Injury Predictive Score (BIPS) for the early identification of need to operate in blunt bowel and mesenteric injuries. Injury. 2022 Jan; 53(1):122-128. Wandling M, Cuschieri J, Kozar R, O'Meara L, Celii A, Starr W, Burlew CC, Todd SR, de Leon A, McIntyre RC, Urban S, Biffl WL, Bayat D, Dunn J, Peck K, Rooney AS, Kornblith LZ, Callcut RA, Lollar DI, Ambroz E, Leichtle SW, Aboutanos MB, Schroeppel T, Hennessy EA, Russo R, McNutt M. PMID: 34380598.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    25. The Covid-19 Pandemic: Lessons Learned for Sustained Trauma Preparedness and Responses. Ann Surg. 2021 06 01; 273(6):1051-1059. Cuschieri J, Robinson B, Lynch J, Mitchell S, Arbabi S, Bryson C, Sayre M, Maier RV, Bulger E. PMID: 33378302.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    26. Aspirin versus anticoagulation for stroke prophylaxis in blunt cerebrovascular injury: a propensity-matched retrospective cohort study. J Neurosurg. 2021 Mar 26; 135(5):1413-1420. Bonow RH, Witt CE, Mossa-Basha M, Cuschieri J, Arbabi S, Vavilala MS, Rivara FP, Chesnut RM. PMID: 33770758.
      View in: PubMed   Mentions:    Fields:    
    27. PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients. BMJ Open. 2021 03 24; 11(3):e041845. O'Toole RV, Stein DM, Frey KP, O'Hara NN, Scharfstein DO, Slobogean GP, Taylor TJ, Haac BE, Carlini AR, Manson TT, Sudini K, Mullins CD, Wegener ST, Firoozabadi R, Haut ER, Bosse MJ, Seymour RB, Holden MB, Gitajn IL, Goldhaber SZ, Eastman AL, Jurkovich GJ, Vallier HA, Gary JL, Kleweno CP, Cuschieri J, Marvel D, Castillo RC, METRC. PMID: 33762229; PMCID: PMC7993181.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    28. Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document. Trauma Surg Acute Care Open. 2021; 6(1):e000643. Rappold JF, Sheppard FR, Carmichael Ii SP, Cuschieri J, Ley E, Rangel E, Seshadri AJ, Michetti CP. PMID: 33718615; PMCID: PMC7908288.
      View in: PubMed   Mentions: 20  
    29. Distinct immunologic endotypes are associated with clinical trajectory after severe blunt trauma and hemorrhagic shock. J Trauma Acute Care Surg. 2021 02 01; 90(2):257-267. Brakenridge SC, Wang Z, Cox M, Raymond S, Hawkins R, Darden D, Ghita G, Brumback B, Cuschieri J, Maier RV, Moore FA, Mohr AM, Efron PA, Moldawer LL. PMID: 33214489; PMCID: PMC8194286.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    30. Persistent metabolomic alterations characterize chronic critical illness after severe trauma. J Trauma Acute Care Surg. 2021 01 01; 90(1):35-45. Horn DL, Bettcher LF, Navarro SL, Pascua V, Neto FC, Cuschieri J, Raftery D, O'Keefe GE. PMID: 33017357; PMCID: PMC8011937.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    31. Changes in error patterns in unanticipated trauma deaths during 20 years: In pursuit of zero preventable deaths. J Trauma Acute Care Surg. 2020 12; 89(6):1046-1053. LaGrone LN, McIntyre L, Riggle A, Robinson BRH, Maier RV, Bulger E, Cuschieri J. PMID: 32773673.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis. N Engl J Med. 2020 11 12; 383(20):1907-1919. CODA Collaborative, Flum DR, Davidson GH, Monsell SE, Shapiro NI, Odom SR, Sanchez SE, Drake FT, Fischkoff K, Johnson J, Patton JH, Evans H, Cuschieri J, Sabbatini AK, Faine BA, Skeete DA, Liang MK, Sohn V, McGrane K, Kutcher ME, Chung B, Carter DW, Ayoung-Chee P, Chiang W, Rushing A, Steinberg S, Foster CS, Schaetzel SM, Price TP, Mandell KA, Ferrigno L, Salzberg M, DeUgarte DA, Kaji AH, Moran GJ, Saltzman D, Alam HB, Park PK, Kao LS, Thompson CM, Self WH, Yu JT, Wiebusch A, Winchell RJ, Clark S, Krishnadasan A, Fannon E, Lavallee DC, Comstock BA, Bizzell B, Heagerty PJ, Kessler LG, Talan DA. PMID: 33017106.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    33. Society of Interventional Radiology Clinical Practice Guideline for Inferior Vena Cava Filters in the Treatment of Patients with Venous Thromboembolic Disease: Developed in collaboration with the American College of Cardiology, American College of Chest Physicians, American College of Surgeons Committee on Trauma, American Heart Association, Society for Vascular Surgery, and Society for Vascular Medicine. J Vasc Interv Radiol. 2020 Oct; 31(10):1529-1544. Kaufman JA, Barnes GD, Chaer RA, Cuschieri J, Eberhardt RT, Johnson MS, Kuo WT, Murin S, Patel S, Rajasekhar A, Weinberg I, Gillespie DL. PMID: 32919823.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    34. Authors' reply: Understanding state-level Medicaid expansion in the context of nationwide data. J Trauma Acute Care Surg. 2020 08; 89(2):e20-e21. Scott JW, Shrime MG, Stewart BT, Arbabi S, Bulger EM, Cuschieri J, Maier RV, Robinson BRH. PMID: 32301881.
      View in: PubMed   Mentions:    Fields:    
    35. Splenic artery angioembolization for high-grade splenic injury: Are we wasting money? Am J Surg. 2021 01; 221(1):204-210. Senekjian L, Cuschieri J, Robinson BRH. PMID: 32693942.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Predictors of mortality, limb loss, and discharge disposition at admission among patients with necrotizing skin and soft tissue infections. J Trauma Acute Care Surg. 2020 07; 89(1):186-191. Horn DL, Shen J, Roberts E, Wang TN, Li KS, O'Keefe GE, Cuschieri J, Bulger EM, Robinson BRH. PMID: 32102045; PMCID: PMC7311238.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    37. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study. Lancet. 2020 07 04; 396(10243):27-38. COVIDSurg Collaborative. PMID: 32479829; PMCID: PMC7259900.
      View in: PubMed   Mentions: 769     Fields:    Translation:HumansCellsPHPublic Health
    38. Prospective Validation of a Transcriptomic Metric in Severe Trauma. Ann Surg. 2020 05; 271(5):802-810. Raymond SL, Hawkins RB, Wang Z, Mira JC, Stortz JA, Han F, Lanz JD, Hennessy LV, Brumback BA, Baker HV, Efron PA, Brakenridge SC, Xiao W, Tompkins RG, Cuschieri J, Moore FA, Maier RV, Moldawer LL. PMID: 30688688; PMCID: PMC6656642.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    39. Proceedings from the Consensus Conference on Trauma Patient-Reported Outcome Measures. J Am Coll Surg. 2020 05; 230(5):819-835. Sakran JV, Ezzeddine H, Schwab CW, Bonne S, Brasel KJ, Burd RS, Cuschieri J, Ficke J, Gaines BA, Giacino JT, Gibran NS, Haider A, Hall EC, Herrera-Escobar JP, Joseph B, Kao L, Kurowski BG, Livingston D, Mandell SP, Nehra D, Sarani B, Seamon M, Yonclas P, Zarzaur B, Stewart R, Bulger E, Nathens AB, Patient Reported Outcome Consortium. PMID: 32201197.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    40. Contemporary hemodynamic monitoring, fluid responsiveness, volume optimization, and endpoints of resuscitation: an AAST critical care committee clinical consensus. Trauma Surg Acute Care Open. 2020; 5(1):e000411. Martin ND, Codner P, Greene W, Brasel K, Michetti C, AAST Critical Care Committee . PMID: 32201737; PMCID: PMC7066619.
      View in: PubMed   Mentions: 4  
    41. Lifting the burden: State Medicaid expansion reduces financial risk for the injured. J Trauma Acute Care Surg. 2020 01; 88(1):51-58. Scott JW, Shrime MG, Stewart BT, Arbabi S, Bulger EM, Cuschieri J, Maier RV, Robinson BRH. PMID: 31524838.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma. Sci Rep. 2019 09 20; 9(1):13648. Stortz JA, Hawkins RB, Holden DC, Raymond SL, Wang Z, Brakenridge SC, Cuschieri J, Moore FA, Maier RV, Moldawer LL, Efron PA. PMID: 31541163; PMCID: PMC6754448.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    43. Ventilator-associated events, not ventilator-associated pneumonia, is associated with higher mortality in trauma patients. J Trauma Acute Care Surg. 2019 08; 87(2):307-314. Meagher AD, Lind M, Senekjian L, Iwuchukwu C, Lynch JB, Cuschieri J, Robinson BRH. PMID: 30939576.
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    44. Authors Response to Commentary on our Manuscript. J Trauma Acute Care Surg. 2019 03; 86(3):554-555. Cook MR, Cuschieri J. PMID: 30444860.
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    45. Trauma Surgeon and Palliative Care Physician Attitudes Regarding Goals-of-Care Delineation for Injured Geriatric Patients. Am J Hosp Palliat Care. 2019 Aug; 36(8):669-674. Cunningham HB, Scielzo SA, Nakonezny PA, Bruns BR, Brasel KJ, Inaba K, Brakenridge SC, Kerby JD, Joseph BA, Mohler MJ, Cuschieri J, Paulk ME, Ekeh AP, Madni TD, Taveras LR, Imran JB, Wolf SE, Phelan HA. PMID: 30614253.
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    46. Burn Surgeon and Palliative Care Physician Attitudes Regarding Goals of Care Delineation for Burned Geriatric Patients. J Burn Care Res. 2018 10 23; 39(6):1000-1005. Cunningham HB, Scielzo SA, Nakonezny PA, Bruns BR, Brasel KJ, Inaba K, Brakenridge SC, Kerby JD, Joseph BA, Mohler MJ, Cuschieri J, Paulk ME, Ekeh AP, Madni TD, Taveras LR, Imran JB, Wolf SE, Phelan HA. PMID: 29771351; PMCID: PMC6454520.
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    47. Decreased Risk of Delirium With Use of Regional Analgesia in Geriatric Trauma Patients With Multiple Rib Fractures. Ann Surg. 2018 09; 268(3):534-540. O'Connell KM, Quistberg DA, Tessler R, Robinson BRH, Cuschieri J, Maier RV, Rivara FP, Vavilala MS, Bhalla PI, Arbabi S. PMID: 30048325.
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    48. Unique Uses of Cooling Strategies. Ther Hypothermia Temp Manag. 2018 09; 8(3):126-130. Lyden P, Paul J, Yokobori S, Cuschieri J. PMID: 30096262.
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    49. Duration of Respiratory Failure After Trauma Is Not Associated With Increased Long-Term Mortality. Crit Care Med. 2018 08; 46(8):1263-1268. Cook MR, O'Connell K, Qiu Q, Riggle AJ, Shoultz TH, Maine RG, Arbabi S, O'Keefe GE, Cuschieri J, Maier RV, Robinson BRH. PMID: 29742591.
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    50. Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the Intensive Care Unit: A Stepped-Wedge Cluster Randomized Clinical Trial. JAMA Surg. 2018 05 01; 153(5):464-470. Parent B, LaGrone LN, Albirair MT, Serina PT, Keller JM, Cuschieri J, Addison EJ, Choe L, Delossantos GB, Gaskill CE, Moon SD, MacDonald JT, Stolzberg MJ, Van Eaton EG, Zech JM, Kritek PA. PMID: 29299602; PMCID: PMC5875375.
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    51. Fellowship training in extracorporeal life support: Characterization and educational needs assessment. J Crit Care. 2018 08; 46:159-161. Cook MR, Badulak J, Çoruh B, Kiraly LN, Zonies D, Cuschieri J, Bulger EM. PMID: 29606413.
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    52. Short-Course Antimicrobial Therapy Does Not Increase Treatment Failure Rate in Patients with Intra-Abdominal Infection Involving Fungal Organisms. Surg Infect (Larchmt). 2018 May/Jun; 19(4):376-381. Elwood NR, Guidry CA, Duane TM, Cuschieri J, Cook CH, O'Neill PJ, Askari R, Napolitano LM, Namias N, Dellinger EP, Watson CM, Banton KL, Blake DP, Hassinger TE, Sawyer RG. PMID: 29565726.
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    53. A cohort study of blunt cerebrovascular injury screening in children: Are they just little adults? J Trauma Acute Care Surg. 2018 01; 84(1):50-57. Cook MR, Witt CE, Bonow RH, Bulger EM, Linnau KF, Arbabi S, Robinson BRH, Cuschieri J. PMID: 28640778; PMCID: PMC6469697.
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    54. The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers. Crit Care Med. 2017 Dec; 45(12):1989-1996. Mira JC, Cuschieri J, Ozrazgat-Baslanti T, Wang Z, Ghita GL, Loftus TJ, Stortz JA, Raymond SL, Lanz JD, Hennessy LV, Brumback B, Efron PA, Baker HV, Moore FA, Maier RV, Moldawer LL, Brakenridge SC. PMID: 28837430; PMCID: PMC5693769.
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    55. Novel Method Suggests Global Superiority of Short-Duration Antibiotics for Intra-abdominal Infections. Clin Infect Dis. 2017 Oct 16; 65(9):1577-1579. Celestin AR, Odom SR, Angelidou K, Evans SR, Coimbra R, Guidry CA, Cuschieri J, Banton KL, O'Neill PJ, Askari R, Namias N, Duane TM, Claridge JA, Dellinger EP, Sawyer RA, Cook CH. PMID: 29020201; PMCID: PMC5850039.
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    56. Does Isolation of Enterococcus Affect Outcomes in Intra-Abdominal Infections? Surg Infect (Larchmt). 2017 Nov/Dec; 18(8):879-885. Sanders JM, Tessier JM, Sawyer R, Dellinger EP, Miller PR, Namias N, West MA, Cook CH, O'Neill PJ, Napolitano L, Rattan R, Cuschieri J, Claridge JA, Guidry CA, Askari R, Banton K, Rotstein O, Moore BJ, Duane TM. PMID: 28994635.
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    57. Transcranial Doppler Microemboli Monitoring for Stroke Risk Stratification in Blunt Cerebrovascular Injury. Crit Care Med. 2017 Oct; 45(10):e1011-e1017. Bonow RH, Witt CE, Mosher BP, Mossa-Basha M, Vavilala MS, Rivara FP, Cuschieri J, Arbabi S, Chesnut RM. PMID: 28658027; PMCID: PMC5600655.
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    58. Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial. JAMA. 2017 08 22; 318(8):731-740. Limaye AP, Stapleton RD, Peng L, Gunn SR, Kimball LE, Hyzy R, Exline MC, Files DC, Morris PE, Frankel SK, Mikkelsen ME, Hite D, Enfield KB, Steingrub J, O'Brien J, Parsons PE, Cuschieri J, Wunderink RG, Hotchkin DL, Chen YQ, Rubenfeld GD, Boeckh M. PMID: 28829877; PMCID: PMC5817487.
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    59. Validation of a Geriatric Trauma Prognosis Calculator: A P.A.L.Li.A.T.E. Consortium Study. J Am Geriatr Soc. 2017 Oct; 65(10):2302-2307. Cook AC, Joseph B, Mohler MJ, Inaba K, Bruns BR, Nakonezny PA, Kerby JD, Brasel KJ, Wolf SE, Cuschieri J, Paulk ME, Rhodes RL, Brakenridge SC, Ekeh AP, Phelan HA. PMID: 28804877.
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    60. A comparison of prognosis calculators for geriatric trauma: A Prognostic Assessment of Life and Limitations After Trauma in the Elderly consortium study. J Trauma Acute Care Surg. 2017 07; 83(1):90-96. Madni TD, Ekeh AP, Brakenridge SC, Brasel KJ, Joseph B, Inaba K, Bruns BR, Kerby JD, Cuschieri J, Mohler MJ, Nakonezny PA, Clark A, Imran J, Wolf SE, Paulk ME, Rhodes RL, Phelan HA. PMID: 28422904.
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    61. Longer-Duration Antimicrobial Therapy Does Not Prevent Treatment Failure in High-Risk Patients with Complicated Intra-Abdominal Infections. Surg Infect (Larchmt). 2017 Aug/Sep; 18(6):659-663. Hassinger TE, Guidry CA, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Napolitano LM, Namias N, Miller PR, Dellinger EP, Coimbra R, Cocanour CS, Banton KL, Cuschieri J, Popovsky K, Sawyer RG. PMID: 28650745; PMCID: PMC5576191.
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    62. Age and Its Impact on Outcomes with Intra-Abdominal Infection. Surg Infect (Larchmt). 2017 Feb/Mar; 18(2):77-82. Farmer D, Tessier JM, Sanders JM, Sawyer RG, Rotstein OD, Dellinger EP, Lipsett PA, Cuschieri J, Miller P, Cook CH, Guidry CA, Askari R, Moore BJ, Duane TM. PMID: 28005468.
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    63. Preventing hospital-acquired venous thromboembolism: Improving patient safety with interdisciplinary teamwork, quality improvement analytics, and data transparency. J Hosp Med. 2016 12; 11 Suppl 2:S38-S43. Schleyer AM, Robinson E, Dumitru R, Taylor M, Hayes K, Pergamit R, Beingessner DM, Zaros MC, Cuschieri J. PMID: 27925422.
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    64. Acute Rehabilitation after Trauma: Does it Really Matter? J Am Coll Surg. 2016 12; 223(6):755-763. Nehra D, Nixon ZA, Lengenfelder C, Bulger EM, Cuschieri J, Maier RV, Arbabi S. PMID: 28193321.
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    65. Patients with Risk Factors for Complications Do Not Require Longer Antimicrobial Therapy for Complicated Intra-Abdominal Infection. Am Surg. 2016 Sep; 82(9):860-6. Rattan R, Allen CJ, Sawyer RG, Mazuski J, Duane TM, Askari R, Banton KL, Claridge JA, Coimbra R, Cuschieri J, Dellinger EP, Evans HL, Guidry CA, Miller PR, O'Neill PJ, Rotstein OD, West MA, Popovsky K, Namias N. PMID: 27670577.
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    66. Sex-based differences in the genomic response, innate immunity, organ dysfunction, and clinical outcomes after severe blunt traumatic injury and hemorrhagic shock. J Trauma Acute Care Surg. 2016 09; 81(3):478-85. Lopez MC, Efron PA, Ozrazgat-Baslanti T, Zhang J, Cuschieri J, Maier RV, Minei JP, Baker HV, Moore FA, Moldawer LL, Brakenridge SC. PMID: 27306446; PMCID: PMC5001949.
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    67. Inclusion of Vancomycin as Part of Broad-Spectrum Coverage Does Not Improve Outcomes in Patients with Intra-Abdominal Infections: A Post Hoc Analysis. Surg Infect (Larchmt). 2016 Dec; 17(6):694-699. Sanders JM, Tessier JM, Sawyer RG, Lipsett PA, Miller PR, Namias N, O'Neill PJ, Dellinger EP, Coimbra R, Guidry CA, Cuschieri J, Banton KL, Cook CH, Moore BJ, Duane TM. PMID: 27483362.
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    68. Surgical Management of Clostridium difficile Infection: The Role of Colectomy. Surg Infect (Larchmt). 2016 Jun; 17(3):343-5. Delano MJ, Cuschieri J. PMID: 27003312.
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    69. Multicenter external validation of the Geriatric Trauma Outcome Score: A study by the Prognostic Assessment of Life and Limitations After Trauma in the Elderly (PALLIATE) consortium. J Trauma Acute Care Surg. 2016 Feb; 80(2):204-9. Cook AC, Joseph B, Inaba K, Nakonezny PA, Bruns BR, Kerby JD, Brasel KJ, Wolf SE, Cuschieri J, Paulk ME, Rhodes RL, Brakenridge SC, Phelan HA. PMID: 26595708.
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    70. Patients with Complicated Intra-Abdominal Infection Presenting with Sepsis Do Not Require Longer Duration of Antimicrobial Therapy. J Am Coll Surg. 2016 Apr; 222(4):440-6. Rattan R, Allen CJ, Sawyer RG, Askari R, Banton KL, Claridge JA, Cocanour CS, Coimbra R, Cook CH, Cuschieri J, Dellinger EP, Duane TM, Evans HL, Lipsett PA, Mazuski JE, Miller PR, O'Neill PJ, Rotstein OD, Namias N. PMID: 26920994.
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    71. The Role of Lipopolysaccharide Structure in Monocyte Activation and Cytokine Secretion. Shock. 2016 Jan; 45(1):22-7. Plevin RE, Knoll M, McKay M, Arbabi S, Cuschieri J. PMID: 26674452; PMCID: PMC5181111.
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    72. Pediatric solid organ injury operative interventions and outcomes at Harborview Medical Center, before and after introduction of a solid organ injury pathway for pediatrics. J Trauma Acute Care Surg. 2015 Aug; 79(2):215-20. Dervan LA, King MA, Cuschieri J, Rivara FP, Weiss NS. PMID: 26218688; PMCID: PMC4716013.
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    73. Prehospital Resuscitation of Traumatic Hemorrhagic Shock with Hypertonic Solutions Worsens Hypocoagulation and Hyperfibrinolysis. Shock. 2015 Jul; 44(1):25-31. Delano MJ, Rizoli SB, Rhind SG, Cuschieri J, Junger W, Baker AJ, Dubick MA, Hoyt DB, Bulger EM. PMID: 25784523; PMCID: PMC4607051.
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    74. Trial of short-course antimicrobial therapy for intraabdominal infection. N Engl J Med. 2015 05 21; 372(21):1996-2005. Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent DL, Lowry SF, Cocanour CS, West MA, Banton KL, Cheadle WG, Lipsett PA, Guidry CA, Popovsky K, STOP-IT Trial Investigators. PMID: 25992746; PMCID: PMC4469182.
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    75. Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma. Ann Surg. 2015 May; 261(5):997-1005. Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators. PMID: 24670858; PMCID: PMC4176550.
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    76. Morbidity and survival probability in burn patients in modern burn care. Crit Care Med. 2015 Apr; 43(4):808-15. Jeschke MG, Pinto R, Kraft R, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Klein MB, Arnoldo BD, Tompkins RG, Herndon DN, Inflammation and the Host Response to Injury Collaborative Research Program. PMID: 25559438; PMCID: PMC4359665.
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    77. Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock. Crit Care. 2015 Mar 04; 19:77. Vanzant EL, Hilton RE, Lopez CM, Zhang J, Ungaro RF, Gentile LF, Szpila BE, Maier RV, Cuschieri J, Bihorac A, Leeuwenburgh C, Moore FA, Baker HV, Moldawer LL, Brakenridge SC, Efron PA, Inflammation and Host Response to Injury Investigators. PMID: 25880307; PMCID: PMC4404112.
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    78. Evolving beyond the vicious triad: Differential mediation of traumatic coagulopathy by injury, shock, and resuscitation. J Trauma Acute Care Surg. 2015 Mar; 78(3):516-23. Kutcher ME, Howard BM, Sperry JL, Hubbard AE, Decker AL, Cuschieri J, Minei JP, Moore EE, Brownstein BH, Maier RV, Cohen MJ. PMID: 25710421.
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    79. Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy. Ann Surg. 2014 Aug; 260(2):378-82. Neal MD, Brown JB, Moore EE, Cuschieri J, Maier RV, Minei JP, Billiar TR, Peitzman AB, Cohen MJ, Sperry JL, Inflammation and Host Response to Injury Investigators. PMID: 24424149; PMCID: PMC4096620.
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    80. Pre-hospital aspiration is associated with increased pulmonary complications. Surg Infect (Larchmt). 2015 Apr; 16(2):159-64. Fawcett VJ, Warner KJ, Cuschieri J, Copass M, Grabinsky A, Kwok H, Rea T, Evans HL. PMID: 24896218.
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    81. A better understanding of why murine models of trauma do not recapitulate the human syndrome. Crit Care Med. 2014 Jun; 42(6):1406-13. Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Baslanti TO, McKinley BA, Bihorac A, Cuschieri J, Maier RV, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. PMID: 24413577; PMCID: PMC4283139.
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    82. Benchmarking outcomes in the critically injured burn patient. Ann Surg. 2014 May; 259(5):833-41. Klein MB, Goverman J, Hayden DL, Fagan SP, McDonald-Smith GP, Alexander AK, Gamelli RL, Gibran NS, Finnerty CC, Jeschke MG, Arnoldo B, Wispelwey B, Mindrinos MN, Xiao W, Honari SE, Mason PH, Schoenfeld DA, Herndon DN, Tompkins RG, Inflammation and Host Response to Injury, and Large-Scale Collaborative Research Program. PMID: 24722222; PMCID: PMC4283803.
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    83. Delayed topical p38 MAPK inhibition attenuates full-thickness burn wound inflammatory signaling. J Burn Care Res. 2014 Mar-Apr; 35(2):e83-92. Carter D, Warsen A, Mandell K, Cuschieri J, Maier RV, Arbabi S. PMID: 23666384; PMCID: PMC4180234.
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    84. Differences in end-of-life care in the ICU across patients cared for by medicine, surgery, neurology, and neurosurgery physicians. Chest. 2014 Feb; 145(2):313-321. Kross EK, Engelberg RA, Downey L, Cuschieri J, Hallman MR, Longstreth WT, Tirschwell DL, Curtis JR. PMID: 24114410; PMCID: PMC3913300.
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    85. Determining a core curriculum in surgical infections for fellowship training in acute care surgery using the Delphi technique. Surg Infect (Larchmt). 2013 Dec; 14(6):547-53. May AK, Cuschieri J, Johnson JL, Duane TM, Cherry-Bukowiec JR, Rosengart MR. PMID: 24446894.
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    86. Upper extremity deep vein thrombosis in hospitalized patients: a descriptive study. J Hosp Med. 2014 Jan; 9(1):48-53. Schleyer AM, Jarman KM, Calver P, Cuschieri J, Robinson E, Goss JR. PMID: 24281984.
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    87. Prehospital hypertonic saline resuscitation attenuates the activation and promotes apoptosis of neutrophils in patients with severe traumatic brain injury. Shock. 2013 Nov; 40(5):366-74. Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Baker AJ, Shek PN, Hoyt DB, Bulger EM. PMID: 24088993; PMCID: PMC3913169.
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    88. Determination of burn patient outcome by large-scale quantitative discovery proteomics. Crit Care Med. 2013 Jun; 41(6):1421-34. Finnerty CC, Jeschke MG, Qian WJ, Kaushal A, Xiao W, Liu T, Gritsenko MA, Moore RJ, Camp DG, Moldawer LL, Elson C, Schoenfeld D, Gamelli R, Gibran N, Klein M, Arnoldo B, Remick D, Smith RD, Davis R, Tompkins RG, Herndon DN, Investigators of the Inflammation and the Host Response Glue Grant. PMID: 23507713; PMCID: PMC3660437.
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    89. Trauma-associated human neutrophil alterations revealed by comparative proteomics profiling. Proteomics Clin Appl. 2013 Aug; 7(7-8):571-83. Zhou JY, Krovvidi RK, Gao Y, Gao H, Petritis BO, De AK, Miller-Graziano CL, Bankey PE, Petyuk VA, Nicora CD, Clauss TR, Moore RJ, Shi T, Brown JN, Kaushal A, Xiao W, Davis RW, Maier RV, Tompkins RG, Qian WJ, Camp DG, Smith RD, Inflammation and the Host Response to Injury Large Scale Collaborative Research Program. PMID: 23589343; PMCID: PMC3737403.
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    90. Comparing clinical predictors of deep venous thrombosis versus pulmonary embolus after severe injury: a new paradigm for posttraumatic venous thromboembolism? J Trauma Acute Care Surg. 2013 May; 74(5):1231-7; discussion 1237-8. Brakenridge SC, Henley SS, Kashner TM, Golden RM, Paik DH, Phelan HA, Cohen MJ, Sperry JL, Moore EE, Minei JP, Maier RV, Cuschieri J, Inflammation and the Host Response to Injury Investigators. PMID: 23609272; PMCID: PMC3716365.
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    91. Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients. Crit Care Med. 2013 May; 41(5):1175-85. Cuenca AG, Gentile LF, Lopez MC, Ungaro R, Liu H, Xiao W, Seok J, Mindrinos MN, Ang D, Baslanti TO, Bihorac A, Efron PA, Cuschieri J, Warren HS, Tompkins RG, Maier RV, Baker HV, Moldawer LL, Inflammation and Host Response to Injury Collaborative Research Program. PMID: 23388514; PMCID: PMC3652285.
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    92. Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis. J Trauma Acute Care Surg. 2013 May; 74(5):1207-12; discussion 1212-4. Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators. PMID: 23609269; PMCID: PMC3634596.
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    93. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3507-12. Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG, Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. PMID: 23401516; PMCID: PMC3587220.
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    94. Antiplatelet therapy is associated with decreased transfusion-associated risk of lung dysfunction, multiple organ failure, and mortality in trauma patients. Crit Care Med. 2013 Feb; 41(2):399-404. Harr JN, Moore EE, Johnson J, Chin TL, Wohlauer MV, Maier R, Cuschieri J, Sperry J, Banerjee A, Silliman CC, Sauaia A. PMID: 23263579; PMCID: PMC3557727.
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    95. Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix. J Trauma Acute Care Surg. 2012 Dec; 73(6):1395-400. Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators. PMID: 23064602; PMCID: PMC3540988.
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    96. Who should we feed? Western Trauma Association multi-institutional study of enteral nutrition in the open abdomen after injury. J Trauma Acute Care Surg. 2012 Dec; 73(6):1380-7; discussion 1387-8. Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Nirula R, Millar D, Cohen MJ, Kutcher ME, Haan J, MacNew HG, Ochsner G, Rowell SE, Truitt MS, Moore FO, Pieracci FM, Kaups KL, WTA Study Group. PMID: 22835999.
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    97. Resuscitation of traumatic hemorrhagic shock patients with hypertonic saline-without dextran-inhibits neutrophil and endothelial cell activation. Shock. 2012 Oct; 38(4):341-50. Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Shiu MY, Baker AJ, Li L, Shek PN, Hoyt DB, Bulger EM. PMID: 22777113; PMCID: PMC3455119.
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    98. Hypothermia in massive transfusion: have we been paying enough attention to it? J Trauma Acute Care Surg. 2012 Aug; 73(2):486-91. Reynolds BR, Forsythe RM, Harbrecht BG, Cuschieri J, Minei JP, Maier RV, Moore EE, Billiar EE, Peitzman AB, Sperry JL, Inflammation and Host Response to Injury Investigators. PMID: 23019675.
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    99. Acute respiratory distress syndrome after trauma: development and validation of a predictive model. Crit Care Med. 2012 Aug; 40(8):2295-303. Watkins TR, Nathens AB, Cooke CR, Psaty BM, Maier RV, Cuschieri J, Rubenfeld GD. PMID: 22809905; PMCID: PMC3400931.
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    100. The role and value of surgical critical care, an essential component of Acute Care Surgery, in the Affordable Care Act: a report from the Critical Care Committee and Board of Managers of the American Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2012 Jul; 73(1):20-6. Frankel HL, Butler KL, Cuschieri J, Friese RS, Huynh T, Mohr AM, Schinco MA, Napolitano LM, Britt LD, Coimbra R, Croce MA, Davis JW, Jurkovich GJ, Moore EE, Morris JA, Peitzman AB, Pruitt BA, Rozycki GS, Scalea TM, Meredith JW. PMID: 22743368.
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    101. Active surveillance cultures of methicillin-resistant Staphylococcus aureus as a tool to predict methicillin-resistant S. aureus ventilator-associated pneumonia. Crit Care Med. 2012 May; 40(5):1437-42. Chan JD, Dellit TH, Choudhuri JA, McNamara E, Melius EJ, Evans HL, Cuschieri J, Arbabi S, Lynch JB. PMID: 22511127.
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    102. Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg. 2012 May; 255(5):993-9. Cuschieri J, Johnson JL, Sperry J, West MA, Moore EE, Minei JP, Bankey PE, Nathens AB, Cuenca AG, Efron PA, Hennessy L, Xiao W, Mindrinos MN, McDonald-Smith GP, Mason PH, Billiar TR, Schoenfeld DA, Warren HS, Cobb JP, Moldawer LL, Davis RW, Maier RV, Tompkins RG, Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. PMID: 22470077; PMCID: PMC3327791.
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    103. Ventilator-associated pneumonia rates at major trauma centers compared with a national benchmark: a multi-institutional study of the AAST. J Trauma Acute Care Surg. 2012 May; 72(5):1165-73. Michetti CP, Fakhry SM, Ferguson PL, Cook A, Moore FO, Gross R, AAST Ventilator-Associated Pneumonia Investigators. PMID: 22673241.
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    104. The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock. Crit Care Med. 2012 Apr; 40(4):1129-35. Minei JP, Cuschieri J, Sperry J, Moore EE, West MA, Harbrecht BG, O'Keefe GE, Cohen MJ, Moldawer LL, Tompkins RG, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program. PMID: 22020243; PMCID: PMC3343366.
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    105. Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way. J Trauma Acute Care Surg. 2012 Apr; 72(4):892-8. Neal MD, Hoffman MK, Cuschieri J, Minei JP, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Cohen MJ, Sperry JL. PMID: 22491601; PMCID: PMC3347772.
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    106. Obese patients show a depressed cytokine profile following severe blunt injury. Shock. 2012 Mar; 37(3):253-6. Winfield RD, Delano MJ, Cuenca AG, Cendan JC, Lottenberg L, Efron PA, Maier RV, Remick DG, Moldawer LL, Cuschieri J. PMID: 22266966; PMCID: PMC4001923.
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    107. Ventilator-associated pneumonia: bacteremia and death after traumatic injury. J Trauma Acute Care Surg. 2012 Mar; 72(3):713-9. O'Keefe GE, Caldwell E, Cuschieri J, Wurfel MM, Evans HL. PMID: 22491559; PMCID: PMC6874885.
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    108. Changes in massive transfusion over time: an early shift in the right direction? J Trauma Acute Care Surg. 2012 Jan; 72(1):106-11. Kautza BC, Cohen MJ, Cuschieri J, Minei JP, Brackenridge SC, Maier RV, Harbrecht BG, Moore EE, Billiar TR, Peitzman AB, Sperry JL, Inflammation and the Host Response to Injury Investigators. PMID: 22310123; PMCID: PMC3276234.
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    109. A genomic storm in critically injured humans. J Exp Med. 2011 Dec 19; 208(13):2581-90. Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker HV, Finnerty CC, Jeschke MG, López MC, Klein MB, Gamelli RL, Gibran NS, Arnoldo B, Xu W, Zhang Y, Calvano SE, McDonald-Smith GP, Schoenfeld DA, Storey JD, Cobb JP, Warren HS, Moldawer LL, Herndon DN, Lowry SF, Maier RV, Davis RW, Tompkins RG, Inflammation and Host Response to Injury Large-Scale Collaborative Research Program. PMID: 22110166; PMCID: PMC3244029.
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    110. Increased neutrophil adenosine a3 receptor expression is associated with hemorrhagic shock and injury severity in trauma patients. Shock. 2011 Nov; 36(5):435-9. Bulger EM, Tower CM, Warner KJ, Garland T, Cuschieri J, Rizoli S, Rhind S, Junger WG. PMID: 21841534; PMCID: PMC3204900.
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    111. Pre-hospital intubation factors and pneumonia in trauma patients. Surg Infect (Larchmt). 2011 Oct; 12(5):339-44. Evans HL, Warner K, Bulger EM, Sharar SR, Maier RV, Cuschieri J. PMID: 21933010; PMCID: PMC3607967.
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    112. Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study. PLoS Med. 2011 Sep; 8(9):e1001093. Desai KH, Tan CS, Leek JT, Maier RV, Tompkins RG, Storey JD, Inflammation and the Host Response to Injury Large-Scale Collaborative Research Program. PMID: 21931541; PMCID: PMC3172280.
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    113. The Glue Grant experience: characterizing the post injury genomic response. Eur J Trauma Emerg Surg. 2011 Dec; 37(6):549-58. Cuenca AG, Maier RV, Cuschieri J, Moore EE, Moldawer LL, Tompkins RG, Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. PMID: 26815465; PMCID: PMC6541206.
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    114. Early blood product and crystalloid volume resuscitation: risk association with multiple organ dysfunction after severe blunt traumatic injury. J Trauma. 2011 Aug; 71(2):299-305. Brakenridge SC, Phelan HA, Henley SS, Golden RM, Kashner TM, Eastman AE, Sperry JL, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Minei JP, Inflammation and the Host Response to Injury Investigators. PMID: 21825930; PMCID: PMC3716363.
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    115. Clinical outcomes of linezolid vs vancomycin in methicillin-resistant Staphylococcus aureus ventilator-associated pneumonia: retrospective analysis. J Intensive Care Med. 2011 Nov-Dec; 26(6):385-91. Chan JD, Pham TN, Wong J, Hessel M, Cuschieri J, Neff M, Dellit TH. PMID: 21606058.
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    116. Steroids after severe injury: many unanswered questions. JAMA. 2011 Mar 23; 305(12):1242-3. Bulger EM, Cuschieri J. PMID: 21427379.
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    117. Human transcriptome array for high-throughput clinical studies. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3707-12. Xu W, Seok J, Mindrinos MN, Schweitzer AC, Jiang H, Wilhelmy J, Clark TA, Kapur K, Xing Y, Faham M, Storey JD, Moldawer LL, Maier RV, Tompkins RG, Wong WH, Davis RW, Xiao W, Inflammation and Host Response to Injury Large-Scale Collaborative Research Program. PMID: 21317363; PMCID: PMC3048146.
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    118. Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury. J Trauma. 2011 Feb; 70(2):292-8. Edmonds RD, Cuschieri J, Minei JP, Rosengart MR, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Sperry JL, Inflammation the Host Response to Injury Investigators. PMID: 21307724.
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    119. Sew it up! A Western Trauma Association multi-institutional study of enteric injury management in the postinjury open abdomen. J Trauma. 2011 Feb; 70(2):273-7. Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Crowell K, Nirula R, Haan J, Rowell SE, Kato CM, MacNew H, Ochsner MG, Harrison PB, Fusco C, Sauaia A, Kaups KL, WTA Study Group. PMID: 21307721.
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    120. The association between the transfusion of older blood and outcomes after trauma. Shock. 2011 Jan; 35(1):3-8. Hassan M, Pham TN, Cuschieri J, Warner KJ, Nester T, Maier RV, Shalhub S, O'Keefe GE. PMID: 20823694; PMCID: PMC3079484.
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    121. Identification and interpretation of longitudinal gene expression changes in trauma. PLoS One. 2010 Dec 20; 5(12):e14380. Rajicic N, Cuschieri J, Finkelstein DM, Miller-Graziano CL, Hayden D, Moldawer LL, Moore E, O'Keefe G, Pelik K, Warren HS, Schoenfeld DA, Inflammation and the Host Response to Injury Large Scale Collaborative Research Program. PMID: 21187951; PMCID: PMC3004855.
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    122. Timing of intubation and ventilator-associated pneumonia following injury. Arch Surg. 2010 Nov; 145(11):1041-6. Evans HL, Zonies DH, Warner KJ, Bulger EM, Sharar SR, Maier RV, Cuschieri J. PMID: 21079091.
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    123. Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure. Shock. 2010 Oct; 34(4):346-51. Cuschieri J, Bulger E, Schaeffer V, Sakr S, Nathens AB, Hennessy L, Minei J, Moore EE, O'Keefe G, Sperry J, Remick D, Tompkins R, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program. PMID: 20844410; PMCID: PMC3122160.
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    124. Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics. J Proteome Res. 2010 Sep 03; 9(9):4779-89. Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD, Inflammation and the Host Response to Injury Large Scale Collaborative Research Program. PMID: 20698492; PMCID: PMC2945297.
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    125. Clinical microfluidics for neutrophil genomics and proteomics. Nat Med. 2010 Sep; 16(9):1042-7. Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, Mindrinos MN, Smith RD, Davis RW, Tompkins RG, Toner M, Inflammation and the Host Response to Injury Collaborative Research Program. PMID: 20802500; PMCID: PMC3136804.
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    126. Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline. J Surg Res. 2011 Dec; 171(2):769-76. Schaeffer V, Arbabi S, Garcia IA, Knoll ML, Cuschieri J, Bulger EM, Maier RV. PMID: 20828737; PMCID: PMC3006012.
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    127. Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):9923-8. Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Inflammation and Host Response to Injury Program, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'Keefe G. PMID: 20479259; PMCID: PMC2890487.
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    128. Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patients. Arch Surg. 2010 Mar; 145(3):240-6. Evans HL, Dellit TH, Chan J, Nathens AB, Maier RV, Cuschieri J. PMID: 20231624.
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    129. Traditional resuscitative practices fail to resolve metabolic acidosis in morbidly obese patients after severe blunt trauma. J Trauma. 2010 Feb; 68(2):317-30. Winfield RD, Delano MJ, Lottenberg L, Cendan JC, Moldawer LL, Maier RV, Cuschieri J. PMID: 20154544; PMCID: PMC3955091.
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    130. Differences in outcome between obese and nonobese patients following severe blunt trauma are not consistent with an early inflammatory genomic response. Crit Care Med. 2010 Jan; 38(1):51-8. Winfield RD, Delano MJ, Dixon DJ, Schierding WS, Cendan JC, Lottenberg L, Lopez MC, Baker HV, Cobb JP, Moldawer LL, Maier RV, Cuschieri J. PMID: 19661803; PMCID: PMC4028684.
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    131. Oxidant alterations in CD16 expression are cytoskeletal induced. Shock. 2009 Dec; 32(6):572-7. Cuschieri J, Sakr S, Bulger E, Knoll M, Arbabi S, Maier RV. PMID: 19333136; PMCID: PMC2783368.
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    132. Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury. Ann Surg. 2009 Oct; 250(4):531-9. Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV. PMID: 19730236; PMCID: PMC3047595.
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    133. Analysis of the relationship between longitudinal gene expressions and ordered categorical event data. Stat Med. 2009 Sep 30; 28(22):2817-32. Rajicic N, Finkelstein DM, Schoenfeld DA, Inflammation and Host Response to Injury Research Program Investigators. PMID: 19618375; PMCID: PMC3774167.
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    134. Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma. 2009 Aug; 67(2):221-7; discussion 228-30. Watson GA, Sperry JL, Rosengart MR, Minei JP, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Billiar TR, Peitzman AB, Inflammation and Host Response to Injury Investigators. PMID: 19667872.
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    135. Inflammation and the host response to injury, a Large-Scale Collaborative Project: patient-oriented research core standard operating procedures for clinical care IX. Definitions for complications of clinical care of critically injured patients. J Trauma. 2009 Aug; 67(2):384-8. Evans HL, Cuschieri J, Moore EE, Shapiro MB, Nathens AB, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, West MA, Inflammation and Host Response to Injury Investigators. PMID: 19667895; PMCID: PMC4001934.
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    136. Single-dose etomidate for rapid sequence intubation may impact outcome after severe injury. J Trauma. 2009 Jul; 67(1):45-50. Warner KJ, Cuschieri J, Jurkovich GJ, Bulger EM. PMID: 19590307.
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    137. Assessing statistical significance in microarray experiments using the distance between microarrays. PLoS One. 2009 Jun 16; 4(6):e5838. Hayden D, Lazar P, Schoenfeld D, Inflammation and the Host Response to Injury Investigators. PMID: 19529777; PMCID: PMC2691999.
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    138. A genomic score prognostic of outcome in trauma patients. Mol Med. 2009 Jul-Aug; 15(7-8):220-7. Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG, Inflammation and Host Response to Injury Large Scale Collaborative Research Program. PMID: 19593405; PMCID: PMC2707513.
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    139. Characterization of persistent hyperglycemia: what does it mean postinjury? J Trauma. 2009 Apr; 66(4):1076-82. Sperry JL, Frankel HL, Nathens AB, O'keefe GE, Cuschieri J, Moore EE, Maier RV, Minei JP, Inflammation and the Host Response to Injury Investigators. PMID: 19359917; PMCID: PMC4004069.
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    140. Assessment of functional limitation after necrotizing soft tissue infection. J Burn Care Res. 2009 Mar-Apr; 30(2):301-6. Pham TN, Moore ML, Costa BA, Cuschieri J, Klein MB. PMID: 19165118; PMCID: PMC3042352.
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    141. The utility of early end-tidal capnography in monitoring ventilation status after severe injury. J Trauma. 2009 Jan; 66(1):26-31. Warner KJ, Cuschieri J, Garland B, Carlbom D, Baker D, Copass MK, Jurkovich GJ, Bulger EM. PMID: 19131802.
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    142. The evolution of the diagnostic work-up for stab wounds to the back and flank. Injury. 2009 Jan; 40(1):48-53. Pham TN, Heinberg E, Cuschieri J, Bulger EM, O'Keefe GE, Gross JA, Jurkovich GJ. PMID: 19117560.
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    143. Necrotizing soft tissue infection. Surg Infect (Larchmt). 2008 Dec; 9(6):559-62. Cuschieri J. PMID: 19216666.
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    144. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VIII--Nutritional support of the trauma patient. J Trauma. 2008 Dec; 65(6):1520-8. O'Keefe GE, Shelton M, Cuschieri J, Moore EE, Lowry SF, Harbrecht BG, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program. PMID: 19077652; PMCID: PMC4004065.
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    145. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VII--Guidelines for antibiotic administration in severely injured patients. J Trauma. 2008 Dec; 65(6):1511-9. West MA, Moore EE, Shapiro MB, Nathens AB, Cuschieri J, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program. PMID: 19077651; PMCID: PMC4004064.
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    146. An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma. 2008 Nov; 65(5):986-93. Sperry JL, Ochoa JB, Gunn SR, Alarcon LH, Minei JP, Cuschieri J, Rosengart MR, Maier RV, Billiar TR, Peitzman AB, Moore EE, Inflammation the Host Response to Injury Investigators. PMID: 19001962.
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    147. Inflammation and the host response to injury a large-scale collaborative project: patient-oriented research core standard operating procedure for clinical care X. Guidelines for venous thromboembolism prophylaxis in the trauma patient. J Trauma. 2008 Oct; 65(4):944-50. Cuschieri J, Freeman B, O'Keefe G, Harbrecht BG, Bankey P, Johnson JL, Minei JP, Sperry J, West M, Nathens A, Moore EE, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program. PMID: 18849816; PMCID: PMC4004057.
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    148. Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcomes Assessment Program. Ann Surg. 2008 Oct; 248(4):557-63. SCOAP Collaborative, Cuschieri J, Florence M, Flum DR, Jurkovich GJ, Lin P, Steele SR, Symons RG, Thirlby R. PMID: 18936568.
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    149. Survey of surgical infections currently known (SOSICK): a multicenter examination of antimicrobial use from the surgical infection society scientific studies committee. Surg Infect (Larchmt). 2008 Oct; 9(5):509-14. Namias N, Meizoso JP, Livingston DH, SOSICK Investigators Group. PMID: 18687044.
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    150. Effect of immediate enteral feeding on trauma patients with an open abdomen: protection from nosocomial infections. J Am Coll Surg. 2008 Nov; 207(5):690-7. Dissanaike S, Pham T, Shalhub S, Warner K, Hennessy L, Moore EE, Maier RV, O'Keefe GE, Cuschieri J. PMID: 18954781.
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    151. Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients. J Am Coll Surg. 2008 Oct; 207(4):459-67. Sena MJ, Utter GH, Cuschieri J, Maier RV, Tompkins RG, Harbrecht BG, Moore EE, O'Keefe GE. PMID: 18926446; PMCID: PMC4002002.
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    152. Male gender is associated with excessive IL-6 expression following severe injury. J Trauma. 2008 Mar; 64(3):572-8; discussion 578-9. Sperry JL, Friese RS, Frankel HL, West MA, Cuschieri J, Moore EE, Harbrecht BG, Peitzman AB, Billiar TR, Maier RV, Remick DG, Minei JP, Inflammation and the Host Response to Injury Investigators. PMID: 18332795.
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    153. Emergency department ventilation effects outcome in severe traumatic brain injury. J Trauma. 2008 Feb; 64(2):341-7. Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM. PMID: 18301196.
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    154. Insulin regulates macrophage activation through activin A. Shock. 2008 Feb; 29(2):285-90. Cuschieri J, Bulger E, Grinsell R, Garcia I, Maier RV. PMID: 17693932.
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    155. Mechanistic analysis of macrophage response to IRAK-1 gene knockdown by a smart polymer-antisense oligonucleotide therapeutic. J Biomater Sci Polym Ed. 2008; 19(10):1333-46. Johns RE, El-Sayed ME, Bulmus V, Cuschieri J, Maier R, Hoffman AS, Stayton PS. PMID: 18854126.
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    156. Oxidative stress, lipid rafts, and macrophage reprogramming. Antioxid Redox Signal. 2007 Sep; 9(9):1485-97. Cuschieri J, Maier RV. PMID: 17638545.
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    157. Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core-standard operating procedures for clinical care: VI. Blood glucose control in the critically ill trauma patient. J Trauma. 2007 Sep; 63(3):703-8. Harbrecht BG, Minei JP, Shapiro MB, Nathens AB, Moore EE, West MA, Bankey PE, Cuschieri J, Johnson JL, Maier RV, Inflammation and the Host Response to Injury Scale Collaborative Research Project. PMID: 18073622.
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    158. The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway. Shock. 2007 Jun; 27(6):623-30. Schaeffer V, Cuschieri J, Garcia I, Knoll M, Billgren J, Jelacic S, Bulger E, Maier R. PMID: 17505301; PMCID: PMC6014696.
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    159. The impact of prehospital ventilation on outcome after severe traumatic brain injury. J Trauma. 2007 Jun; 62(6):1330-6; discussion 1336-8. Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM. PMID: 17563643.
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    160. Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock. Ann Surg. 2007 Apr; 245(4):635-41. Bulger EM, Cuschieri J, Warner K, Maier RV. PMID: 17414614; PMCID: PMC1877049.
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    161. The practice of venous thromboembolism prophylaxis in the major trauma patient. J Trauma. 2007 Mar; 62(3):557-62; discussion 562-3. Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV. PMID: 17414328.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    162. Acid sphingomyelinase is required for lipid Raft TLR4 complex formation. Surg Infect (Larchmt). 2007 Feb; 8(1):91-106. Cuschieri J, Bulger E, Billgrin J, Garcia I, Maier RV. PMID: 17381401.
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    163. Vitamin E inhibits endotoxin-mediated transport of phosphatases to lipid rafts. Shock. 2007 Jan; 27(1):19-24. Cuschieri J, Bulger E, Biligren J, Garcia I, Maier RV. PMID: 17172975.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    164. Surgical management of acute necrotizing lung infections. Can Respir J. 2006 Oct; 13(7):369-73. Reimel BA, Krishnadasen B, Cuschieri J, Klein MB, Gross J, Karmy-Jones R. PMID: 17036090; PMCID: PMC2683290.
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    165. Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: a condition reversed by PKC activation. J Leukoc Biol. 2006 Dec; 80(6):1289-97. Cuschieri J, Billigren J, Maier RV. PMID: 16959900.
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    166. Phosphatidylcholine-specific phospholipase C (PC-PLC) is required for LPS-mediated macrophage activation through CD14. J Leukoc Biol. 2006 Aug; 80(2):407-14. Cuschieri J, Billgren J, Maier RV. PMID: 16754725.
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    167. The modeling of the radiation and response green's function of a fluid-loaded cylindrical shell with an external compliant layer. J Acoust Soc Am. 2006 Apr; 119(4):2150-69. Cuschieri JM. PMID: 16642830.
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    168. Mitogen-activated protein kinase (MAPK). Crit Care Med. 2005 Dec; 33(12 Suppl):S417-9. Cuschieri J, Maier RV. PMID: 16340409.
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    169. Accidental self-inflicted nail gun injury to the heart. Injury Extra. 2005; 2(80):407-414. Pritts TA Knight D Davis BR Promebka D Cuschieri J.
    170. Oxidative-induced calcium mobilization is dependent on annexin VI release from lipid rafts. Surgery. 2005 Aug; 138(2):158-64. Cuschieri J, Bulger E, Garcia I, Maier RV. PMID: 16153422.
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    171. Central venous-arterial carbon dioxide difference as an indicator of cardiac index. Intensive Care Med. 2005 Jun; 31(6):818-22. Cuschieri J, Rivers EP, Donnino MW, Katilius M, Jacobsen G, Nguyen HB, Pamukov N, Horst HM. PMID: 15803301.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    172. The role of repeat angiography in the management of pelvic fractures. J Trauma. 2005 Feb; 58(2):227-31. Shapiro M, McDonald AA, Knight D, Johannigman JA, Cuschieri J. PMID: 15706180.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    173. Calcium/calmodulin-dependent kinase II is required for platelet-activating factor priming. Shock. 2005 Feb; 23(2):99-106. Cuschieri J, Bulger E, Garcia I, Jelacic S, Maier RV. PMID: 15665723.
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    174. PKC-zeta is essential for endotoxin-induced macrophage activation. J Surg Res. 2004 Sep; 121(1):76-83. Cuschieri J, Umanskiy K, Solomkin J. PMID: 15313379.
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    175. Implications of lipid raft disintegration: enhanced anti-inflammatory macrophage phenotype. Surgery. 2004 Aug; 136(2):169-75. Cuschieri J. PMID: 15300176.
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    176. Implications of proteasome inhibition: an enhanced macrophage phenotype. Cell Immunol. 2004 Feb; 227(2):140-7. Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV. PMID: 15135296.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    177. Modulation of macrophage responsiveness to lipopolysaccharide by IRAK-1 manipulation. Shock. 2004 Feb; 21(2):182-8. Cuschieri J, Bulmus V, Gourlay D, Garcia I, Hoffman A, Stayton P, Maier RV. PMID: 14752294.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    178. NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation. Surgery. 2003 Aug; 134(2):378-83. Umanskiy K, Robinson C, Cave C, Williams MA, Lentsch AB, Cuschieri J, Solomkin JS. PMID: 12947344.
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    179. Modulation of endotoxin-induced endothelial function by calcium/calmodulin-dependent protein kinase. Shock. 2003 Aug; 20(2):176-82. Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV. PMID: 12865664.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    180. Platelet-activating factor acetylhydrolase inhibits alveolar macrophage activation in vivo. Shock. 2003 Jul; 20(1):17-22. Bulger EM, Gourlay D, Cuschieri J, Jelacic S, Staudenmeyer K, Garcia I, Maier RV. PMID: 12813363.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    181. Endotoxin-induced endothelial cell proinflammatory phenotypic differentiation requires stress fiber polymerization. Shock. 2003 May; 19(5):433-9. Cuschleri J, Gourlay D, Garcia I, Jelacic S, Maier RV. PMID: 12744486.
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    182. Modulation of endotoxin-induced endothelial activity by microtubule depolymerization. J Trauma. 2003 Jan; 54(1):104-12; discussion 112-3. Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV. PMID: 12544905.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    183. Platelet-activating factor priming of inflammatory cell activity requires cellular adherence. Surgery. 2002 Aug; 132(2):157-66. Cuschieri J, Gourlay D, Bulger E, Garcia I, Jelacic S, Maier RV. PMID: 12219006.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    184. Slow channel calcium inhibition blocks proinflammatory gene signaling and reduces macrophage responsiveness. J Trauma. 2002 Mar; 52(3):434-42. Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV. PMID: 11901316.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    185. Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin. J Immunol. 2002 Feb 01; 168(3):1389-96. Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV. PMID: 11801680.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    186. Role of bronchoscopy in massive hemoptysis. Chest Surg Clin N Am. 2001 Nov; 11(4):873-906. Karmy-Jones R, Cuschieri J, Vallières E. PMID: 11780301.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    187. Clearing the cervical spine in victims of blunt assault to the head and neck: what is necessary? Am Surg. 2000 Apr; 66(4):326-30; discussion 330-1. Patton JH, Kralovich KA, Cuschieri J, Gasparri M. PMID: 10776867.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    188. Anterior mediastinal abscess after closed sternal fracture. J Trauma. 1999 Sep; 47(3):551-4. Cuschieri J, Kralovich KA, Patton JH, Horst HM, Obeid FN, Karmy-Jones R. PMID: 10498313.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans