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Immediate use cryoprecipitate products provide lasting organ protection in a rodent model of trauma/hemorrhagic shock and prolonged hypotensive resuscitation. J Trauma Acute Care Surg. 2023 10 01; 95(4):529-534.
Zeineddin A, Wu F, Cao S, Corash L, Pati S, Kozar RA. PMID: 37314745.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Early lyophilized cryoprecipitate enhances the ADAMTS13/VWF ratio to reduce systemic endotheliopathy and lessen lung injury in a mouse multiple-trauma hemorrhage model. J Trauma Acute Care Surg. 2023 08 01; 95(2S Suppl 1):S137-S143.
Zeineddin A, Wu F, Dong JF, Vesselinov R, Neal MD, Corash L, Pati S, Kozar RA. PMID: 37211640; PMCID: PMC10389395.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Histone deacetylase-6 modulates the effects of 4°C platelets on vascular endothelial permeability. Blood Adv. 2023 04 11; 7(7):1241-1257.
Miyazawa B, Trivedi A, Vivona L, Lin M, Potter D, Nair A, Barry M, Cap AP, Pati S. PMID: 36375044; PMCID: PMC10090218.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
-
RECOVERY OF ENDOTHELIOPATHY AT 24 HOURS IN AN ESTABLISHED MOUSE MODEL OF HEMORRHAGIC SHOCK AND TRAUMA. Shock. 2022 10 01; 58(4):313-320.
Barry M, Trivedi A, Vivona LR, Chui J, Pathipati P, Miyazawa B, Pati S. PMID: 36256627.
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PubMed Mentions:
3 Fields:
Translation:
Animals
-
Biomarkers of endothelial cell dysfunction persist beyond resuscitation in patients with hemorrhagic shock. J Trauma Acute Care Surg. 2022 11 01; 93(5):572-578.
Zeineddin A, Wu F, Chao W, Zou L, Vesselinov R, Chipman AM, Dong JF, Huang H, Pati S, Kozar RA. PMID: 35939376; PMCID: PMC9613546.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Lyophilized plasma resuscitation downregulates inflammatory gene expression in a mouse model of sepsis. J Trauma Acute Care Surg. 2022 08 01; 93(2S Suppl 1):S119-S127.
Barry M, Wu F, Pati S, Chipman A, Geng H, Kozar R. PMID: 35881828.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
FFP maintains normal coagulation while Kcentra induces a hypercoagulable state in a porcine model of pulmonary contusion and hemorrhagic shock. J Trauma Acute Care Surg. 2022 07 01; 93(1):124-129.
Dixon A, Beiling M, Smith S, Behrens B, Appleman L, Rick E, Murphy J, Madtson B, McCully B, Goodman A, Kanlerd A, Schaller T, Subramanian S, Trivedi A, Pati S, Schreiber M. PMID: 35261373.
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PubMed Mentions: Fields:
Translation:
Animals
-
Mesenchymal stem cell extracellular vesicles mitigate vascular permeability and injury in the small intestine and lung in a mouse model of hemorrhagic shock and trauma. J Trauma Acute Care Surg. 2022 03 01; 92(3):489-498.
Barry M, Trivedi A, Pathipati P, Miyazawa BY, Vivona LR, Togarrati PP, Khakoo M, Tanner H, Norris P, Pati S. PMID: 34882596; PMCID: PMC8866219.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Treating the endotheliopathy of SARS-CoV-2 infection with plasma: Lessons learned from optimized trauma resuscitation with blood products. Transfusion. 2021 07; 61 Suppl 1:S336-S347.
Pati S, Fennern E, Holcomb JB, Barry M, Trivedi A, Cap AP, Martin MJ, Wade C, Kozar R, Cardenas JC, Rappold JF, Spiegel R, Schreiber MA. PMID: 34269437; PMCID: PMC8446992.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Cryoprecipitate attenuates the endotheliopathy of trauma in mice subjected to hemorrhagic shock and trauma. J Trauma Acute Care Surg. 2021 06 01; 90(6):1022-1031.
Barry M, Trivedi A, Miyazawa BY, Vivona LR, Khakoo M, Zhang H, Pathipati P, Bagri A, Gatmaitan MG, Kozar R, Stein D, Pati S. PMID: 33797484; PMCID: PMC8141010.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Evidence-Based and Clinically Relevant Outcomes for Hemorrhage Control Trauma Trials. Ann Surg. 2021 03 01; 273(3):395-401.
Holcomb JB, Moore EE, Sperry JL, Jansen JO, Schreiber MA, Del Junco DJ, Spinella PC, Sauaia A, Brohi K, Bulger EM, Cap AP, Hess JR, Jenkins D, Lewis RJ, Neal MD, Newgard C, Pati S, Pusateri AE, Rizoli S, Russell RT, Shackelford SA, Stein DM, Steiner ME, Wang H, Ward KR, Young P. PMID: 33065652.
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PubMed Mentions:
20 Fields:
Translation:
Humans
-
Freeze-dried platelets promote clot formation, attenuate endothelial cell permeability, and decrease pulmonary vascular leak in a murine model of hemorrhagic shock. J Trauma Acute Care Surg. 2021 02 01; 90(2):203-214.
Trivedi A, Potter DR, Miyazawa BY, Lin M, Vivona LR, Khakoo MA, Antebi B, Lee A, Ishler B, Dickerson M, Kozar R, Schreiber MA, Holcomb JB, Fitzpatrick GM, Pati S. PMID: 33060537.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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The effects of human prothrombin complex concentrate on hemorrhagic shock-induced lung injury in rats: Implications for testing human blood products in rodents. J Trauma Acute Care Surg. 2020 12; 89(6):1068-1075.
Potter DR, Trivedi A, Lin M, Miyazawa BY, Vivona LR, McCully B, Nair A, Schreiber MA, Pati S. PMID: 32697449.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Fresh frozen plasma attenuates lung injury in a novel model of prolonged hypotensive resuscitation. J Trauma Acute Care Surg. 2020 08; 89(2S Suppl 2):S118-S125.
Chipman AM, Wu F, Pati S, Burdette AJ, Glaser JJ, Kozar RA. PMID: 32282752; PMCID: PMC7830779.
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PubMed Mentions:
2 Fields:
Translation:
Animals
-
Resuscitative Strategies to Modulate the Endotheliopathy of Trauma: From Cell to Patient. Shock. 2020 05; 53(5):575-584.
Wu F, Chipman A, Pati S, Miyasawa B, Corash L, Kozar RA. PMID: 31090680; PMCID: PMC6842415.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Aggressive treatment of acute kidney injury and hyperkalemia improves survival in a combat relevant trauma model in swine. Am J Surg. 2020 05; 219(5):860-864.
Smith S, Behrens B, McCully B, Murphy J, Bommiasamy A, Goodman A, Dewey E, Pati S, Schreiber M. PMID: 32245610.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
Is all plasma created equal? A pilot study of the effect of interdonor variability. J Trauma Acute Care Surg. 2020 01; 88(1):121-127.
Chipman AM, Pati S, Potter D, Wu F, Lin M, Kozar RA. PMID: 31688783; PMCID: PMC7055504.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Platelet-derived- Extracellular Vesicles Promote Hemostasis and Prevent the Development of Hemorrhagic Shock. Sci Rep. 2019 11 27; 9(1):17676.
Lopez E, Srivastava AK, Burchfield J, Wang YW, Cardenas JC, Togarrati PP, Miyazawa B, Gonzalez E, Holcomb JB, Pati S, Wade CE. PMID: 31776369; PMCID: PMC6881357.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Gaps in the knowledge of human platelet lysate as a cell culture supplement for cell therapy: a joint publication from the AABB and the International Society for Cell & Gene Therapy. Transfusion. 2019 11; 59(11):3448-3460.
Bieback K, Fernandez-Muñoz B, Pati S, Schäfer R. PMID: 31412158.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Regulation of endothelial cell permeability by platelet-derived extracellular vesicles. J Trauma Acute Care Surg. 2019 06; 86(6):931-942.
Miyazawa B, Trivedi A, Togarrati PP, Potter D, Baimukanova G, Vivona L, Lin M, Lopez E, Callcut R, Srivastava AK, Kornblith LZ, Fields AT, Schreiber MA, Wade CE, Holcomb JB, Pati S. PMID: 31124890; PMCID: PMC7381393.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Bone marrow donor selection and characterization of MSCs is critical for pre-clinical and clinical cell dose production. J Transl Med. 2019 04 17; 17(1):128.
Trivedi A, Miyazawa B, Gibb S, Valanoski K, Vivona L, Lin M, Potter D, Stone M, Norris PJ, Murphy J, Smith S, Schreiber M, Pati S. PMID: 30995929; PMCID: PMC6469059.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Regulation of Endothelial Cell Permeability by Platelet-Derived Extracellular Vesicles. J Trauma Acute Care Surg. 2019 Feb 13.
Miyazawa B, Trivedi A, Togarrati PP, Potter D, Baimukanova G, Vivona L, Lin M, Lopez E, Callcut R, Srivastava AK, Kornblith LZ, Fields AT, Schreiber MA, Wade CE, Holcomb JB, Pati S. PMID: 30768560.
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PubMed Mentions:
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Introduction to the supplement on cellular therapies in trauma and critical care medicine. Transfusion. 2019 02; 59(S1):831-833.
Pati S, Schreiber M, Rappold J. PMID: 30737819.
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PubMed Mentions: Fields:
Translation:
Humans
-
Barriers to clinical research in trauma. Transfusion. 2019 02; 59(S1):846-853.
Miskimins R, Pati S, Schreiber M. PMID: 30585332.
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PubMed Mentions:
7 Fields:
Translation:
Humans
-
Multipotent Adult Progenitor Cells, but Not Tissue Inhibitor of Matrix Metalloproteinase-3, Increase Tissue Sparing and Reduce Urological Complications following Spinal Cord Injury. J Neurotrauma. 2019 05 01; 36(9):1416-1427.
Jones JM, DePaul MA, Gregory CR, Lang BT, Xie H, Zhu M, Rutten MJ, Mays RW, Busch SA, Pati S, Gregory KW. PMID: 30251917.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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A combat relevant model for the creation of acute lung injury in swine. J Trauma Acute Care Surg. 2018 07; 85(1S Suppl 2):S39-S43.
Smith S, McCully B, Bommiasamy A, Murphy J, Behrens B, Pati S, Goodman A, Schreiber M. PMID: 29283971.
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PubMed Mentions: Fields:
Translation:
Animals
-
Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury. Trauma Surg Acute Care Open. 2018; 3(1):e000171.
Hendrickson CM, Gibb SL, Miyazawa BY, Keating SM, Ross E, Conroy AS, Calfee CS, Pati S, Cohen MJ. PMID: 30023434; PMCID: PMC6045722.
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PubMed Mentions:
5
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Platelet-Derived Microvesicles: A Potential Therapy for Trauma-Induced Coagulopathy. Shock. 2018 03; 49(3):243-248.
Lopez E, Srivastava AK, Pati S, Holcomb JB, Wade CE. PMID: 28858139.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Cellular therapies and stem cell applications in trauma. Am J Surg. 2018 05; 215(5):963-972.
Wang Y, Pati S, Schreiber M. PMID: 29502858.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Lyophilized plasma attenuates vascular permeability, inflammation and lung injury in hemorrhagic shock. PLoS One. 2018; 13(2):e0192363.
Pati S, Peng Z, Wataha K, Miyazawa B, Potter DR, Kozar RA. PMID: 29394283; PMCID: PMC5796727.
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PubMed Mentions:
21 Fields:
Translation:
Animals
-
Mesenchymal stem cell-derived extracellular vesicles attenuate pulmonary vascular permeability and lung injury induced by hemorrhagic shock and trauma. J Trauma Acute Care Surg. 2018 02; 84(2):245-256.
Potter DR, Miyazawa BY, Gibb SL, Deng X, Togaratti PP, Croze RH, Srivastava AK, Trivedi A, Matthay M, Holcomb JB, Schreiber MA, Pati S. PMID: 29251710; PMCID: PMC6378956.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
-
Plasma Resuscitation Improved Survival in a Cecal Ligation and Puncture Rat Model of Sepsis. Shock. 2018 Jan; 49(1):53-61.
Chang R, Holcomb JB, Johansson PI, Pati S, Schreiber MA, Wade CE. PMID: 28591008; PMCID: PMC5718978.
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PubMed Mentions:
21 Fields:
Translation:
Animals
-
Cellular therapies in trauma and critical care medicine: Looking towards the future. PLoS Med. 2017 Jul; 14(7):e1002343.
Pati S, Rasmussen TE. PMID: 28700606; PMCID: PMC5507410.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Resuscitation of Hypotensive Traumatic Brain Injured Animals With Spray-Dried Plasma Does Not Adversely Alter Physiology and Improves Blood-Brain Barrier Function. Mil Med. 2017 07; 182(7):e1706-e1711.
McDaniel S, Golla S, Moore AN, DaCorta J, Bode A, Pati S, Dash PK, Zhao J. PMID: 28810961.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Serum from dengue virus-infected patients with and without plasma leakage differentially affects endothelial cells barrier function in vitro. PLoS One. 2017; 12(6):e0178820.
Tramontini Gomes de Sousa Cardozo F, Baimukanova G, Lanteri MC, Keating SM, Moraes Ferreira F, Heitman J, Pannuti CS, Pati S, Romano CM, Cerdeira Sabino E. PMID: 28586397; PMCID: PMC5460851.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
-
Concise Review: Mesenchymal Stem (Stromal) Cells: Biology and Preclinical Evidence for Therapeutic Potential for Organ Dysfunction Following Trauma or Sepsis. Stem Cells. 2017 02; 35(2):316-324.
Matthay MA, Pati S, Lee JW. PMID: 27888550.
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PubMed Mentions:
91 Fields:
Translation:
HumansAnimalsCells
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Plasma Transfusion: History, Current Realities, and Novel Improvements. Shock. 2016 11; 46(5):468-479.
Watson JJ, Pati S, Schreiber MA. PMID: 27380536.
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PubMed Mentions:
17 Fields:
Translation:
Humans
-
Lack of species-specific difference in pulmonary function when using mouse versus human plasma in a mouse model of hemorrhagic shock. J Trauma Acute Care Surg. 2016 11; 81(5 Suppl 2 Proceedings of the 2015 Military Health System Research Symposium):S171-S176.
Peng Z, Pati S, Fontaine MJ, Hall K, Herrera AV, Kozar RA. PMID: 27768665; PMCID: PMC5267480.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Wnt3a, a Protein Secreted by Mesenchymal Stem Cells Is Neuroprotective and Promotes Neurocognitive Recovery Following Traumatic Brain Injury. Stem Cells. 2016 05; 34(5):1263-72.
Zhao Y, Gibb SL, Zhao J, Moore AN, Hylin MJ, Menge T, Xue H, Baimukanova G, Potter D, Johnson EM, Holcomb JB, Cox CS, Dash PK, Pati S. PMID: 26840479.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Modulating the endotheliopathy of trauma: Factor concentrate versus fresh frozen plasma. J Trauma Acute Care Surg. 2016 Apr; 80(4):576-84; discussion 584-5.
Pati S, Potter DR, Baimukanova G, Farrel DH, Holcomb JB, Schreiber MA. PMID: 26808040.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Dried plasma: state of the science and recent developments. Transfusion. 2016 04; 56 Suppl 2:S128-39.
Pusateri AE, Given MB, Schreiber MA, Spinella PC, Pati S, Kozar RA, Khan A, Dacorta JA, Kupferer KR, Prat N, Pidcoke HF, Macdonald VW, Malloy WW, Sailliol A, Cap AP. PMID: 27100749.
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PubMed Mentions:
27 Fields:
Translation:
HumansPHPublic Health
-
Platelets regulate vascular endothelial stability: assessing the storage lesion and donor variability of apheresis platelets. Transfusion. 2016 Mar; 56 Suppl 1:S65-75.
Baimukanova G, Miyazawa B, Potter DR, Muench MO, Bruhn R, Gibb SL, Spinella PC, Cap AP, Cohen MJ, Pati S. PMID: 27001364; PMCID: PMC5098902.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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The effects of 22°C and 4°C storage of platelets on vascular endothelial integrity and function. Transfusion. 2016 Mar; 56 Suppl 1:S52-64.
Baimukanova G, Miyazawa B, Potter DR, Gibb SL, Keating S, Danesh A, Beyer A, Dayter Y, Bruhn R, Muench MO, Cap AP, Norris PJ, Spinella P, Cohen M, Pati S. PMID: 27001362.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
-
Cellular Therapies in Trauma and Critical Care Medicine: Forging New Frontiers. Shock. 2015 Dec; 44(6):505-23.
Pati S, Pilia M, Grimsley JM, Karanikas AT, Oyeniyi B, Holcomb JB, Cap AP, Rasmussen TE. PMID: 26428845; PMCID: PMC4851225.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
-
Plasma-Mediated Gut Protection After Hemorrhagic Shock is Lessened in Syndecan-1-/- Mice. Shock. 2015 Nov; 44(5):452-7.
Ban K, Peng Z, Pati S, Witkov RB, Park PW, Kozar RA. PMID: 26263434; PMCID: PMC4816460.
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PubMed Mentions:
15 Fields:
Translation:
Animals
-
TIMP3 Attenuates the Loss of Neural Stem Cells, Mature Neurons and Neurocognitive Dysfunction in Traumatic Brain Injury. Stem Cells. 2015 Dec; 33(12):3530-44.
Gibb SL, Zhao Y, Potter D, Hylin MJ, Bruhn R, Baimukanova G, Zhao J, Xue H, Abdel-Mohsen M, Pillai SK, Moore AN, Johnson EM, Cox CS, Dash PK, Pati S. PMID: 26299440.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Syndecan-1 restitution by plasma after hemorrhagic shock. J Trauma Acute Care Surg. 2015 Jun; 78(6 Suppl 1):S83-6.
Kozar RA, Pati S. PMID: 26002270; PMCID: PMC4841450.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
-
Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock. J Trauma Acute Care Surg. 2015 Jun; 78(6 Suppl 1):S7-S17.
Potter DR, Baimukanova G, Keating SM, Deng X, Chu JA, Gibb SL, Peng Z, Muench MO, Fomin ME, Spinella PC, Kozar R, Pati S. PMID: 26002267.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
-
Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients. J Transl Med. 2015 Apr 12; 13:117.
Rahbar E, Cardenas JC, Baimukanova G, Usadi B, Bruhn R, Pati S, Ostrowski SR, Johansson PI, Holcomb JB, Wade CE. PMID: 25889764; PMCID: PMC4397670.
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PubMed Mentions:
96 Fields:
Translation:
HumansCells
-
The whole is greater than the sum of its parts: hemostatic profiles of whole blood variants. J Trauma Acute Care Surg. 2014 Dec; 77(6):818-27.
Kornblith LZ, Howard BM, Cheung CK, Dayter Y, Pandey S, Busch MP, Pati S, Callcut RA, Vilardi RF, Redick BJ, Nelson MF, Cohen MJ. PMID: 25051379.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Never-frozen liquid plasma blocks endothelial permeability as effectively as thawed fresh frozen plasma. J Trauma Acute Care Surg. 2014 Jul; 77(1):28-33; discussion 33.
Cao Y, Dua A, Matijevic N, Wang YW, Pati S, Wade CE, Ko TC, Holcomb JB. PMID: 24977751.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps. Shock. 2014 May; 41 Suppl 1:3-12.
Jenkins DH, Rappold JF, Badloe JF, Berséus O, Blackbourne L, Brohi KH, Butler FK, Cap AP, Cohen MJ, Davenport R, DePasquale M, Doughty H, Glassberg E, Hervig T, Hooper TJ, Kozar R, Maegele M, Moore EE, Murdock A, Ness PM, Pati S, Rasmussen T, Sailliol A, Schreiber MA, Sunde GA, van de Watering LM, Ward KR, Weiskopf RB, White NJ, Strandenes G, Spinella PC. PMID: 24430539; PMCID: PMC4309265.
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PubMed Mentions:
45 Fields:
Translation:
Humans
-
Fresh frozen plasma lessens pulmonary endothelial inflammation and hyperpermeability after hemorrhagic shock and is associated with loss of syndecan 1. Shock. 2013 Sep; 40(3):195-202.
Peng Z, Pati S, Potter D, Brown R, Holcomb JB, Grill R, Wataha K, Park PW, Xue H, Kozar RA. PMID: 23807246; PMCID: PMC3764452.
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PubMed Mentions:
82 Fields:
Translation:
HumansAnimalsCells
-
Autologous bone marrow mononuclear cells therapy attenuates activated microglial/macrophage response and improves spatial learning after traumatic brain injury. J Trauma Acute Care Surg. 2013 Sep; 75(3):410-6.
Bedi SS, Walker PA, Shah SK, Jimenez F, Thomas CP, Smith P, Hetz RA, Xue H, Pati S, Dash PK, Cox CS. PMID: 23928737; PMCID: PMC4086922.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
-
Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity. Sci Transl Med. 2013 May 29; 5(187):187ra69.
Chintalgattu V, Rees ML, Culver JC, Goel A, Jiffar T, Zhang J, Dunner K, Pati S, Bankson JA, Pasqualini R, Arap W, Bryan NS, Taegtmeyer H, Langley RR, Yao H, Kupferman ME, Entman ML, Dickinson ME, Khakoo AY. PMID: 23720580; PMCID: PMC3833098.
View in:
PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
-
Spray-dried plasma and fresh frozen plasma modulate permeability and inflammation in vitro in vascular endothelial cells. Transfusion. 2013 Jan; 53 Suppl 1:80S-90S.
Wataha K, Menge T, Deng X, Shah A, Bode A, Holcomb JB, Potter D, Kozar R, Spinella PC, Pati S. PMID: 23301978.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Optimal trauma resuscitation with plasma as the primary resuscitative fluid: the surgeon's perspective. Hematology Am Soc Hematol Educ Program. 2013; 2013:656-9.
Holcomb JB, Pati S. PMID: 24319247.
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PubMed Mentions:
37 Fields:
Translation:
Humans
-
Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury. Sci Transl Med. 2012 Nov 21; 4(161):161ra150.
Menge T, Zhao Y, Zhao J, Wataha K, Gerber M, Zhang J, Letourneau P, Redell J, Shen L, Wang J, Peng Z, Xue H, Kozar R, Cox CS, Khakoo AY, Holcomb JB, Dash PK, Pati S. PMID: 23175708; PMCID: PMC3890105.
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PubMed Mentions:
81 Fields:
Translation:
HumansAnimalsCells
-
Human mesenchymal stem cells inhibit endothelial proliferation and angiogenesis via cell-cell contact through modulation of the VE-Cadherin/β-catenin signaling pathway. Stem Cells Dev. 2013 Jan 01; 22(1):148-57.
Menge T, Gerber M, Wataha K, Reid W, Guha S, Cox CS, Dash P, Reitz MS, Khakoo AY, Pati S. PMID: 22734943; PMCID: PMC3528090.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
-
Caffeic Acid phenethyl ester protects blood-brain barrier integrity and reduces contusion volume in rodent models of traumatic brain injury. J Neurotrauma. 2012 Apr 10; 29(6):1209-18.
Zhao J, Pati S, Redell JB, Zhang M, Moore AN, Dash PK. PMID: 22150135; PMCID: PMC3325550.
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PubMed Mentions:
22 Fields:
Translation:
Animals
-
Aged plasma transfusion increases mortality in a rat model of uncontrolled hemorrhage. J Trauma. 2011 Nov; 71(5):1115-9.
Letourneau PA, McManus M, Sowards K, Wang W, Wang YW, Matijevic N, Pati S, Wade CE, Holcomb JB. PMID: 22071917; PMCID: PMC3217202.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock. PLoS One. 2011; 6(9):e25171.
Pati S, Gerber MH, Menge TD, Wataha KA, Zhao Y, Baumgartner JA, Zhao J, Letourneau PA, Huby MP, Baer LA, Salsbury JR, Kozar RA, Wade CE, Walker PA, Dash PK, Cox CS, Doursout MF, Holcomb JB. PMID: 21980392; PMCID: PMC3182198.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
-
Involvement of the glycogen synthase kinase-3 signaling pathway in TBI pathology and neurocognitive outcome. PLoS One. 2011; 6(9):e24648.
Dash PK, Johnson D, Clark J, Orsi SA, Zhang M, Zhao J, Grill RJ, Moore AN, Pati S. PMID: 21935433; PMCID: PMC3174188.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
-
Modulation of syndecan-1 shedding after hemorrhagic shock and resuscitation. PLoS One. 2011; 6(8):e23530.
Haywood-Watson RJ, Holcomb JB, Gonzalez EA, Peng Z, Pati S, Park PW, Wang W, Zaske AM, Menge T, Kozar RA. PMID: 21886795; PMCID: PMC3158765.
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PubMed Mentions:
92 Fields:
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HumansCells
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Increased platelet:RBC ratios are associated with improved survival after massive transfusion. J Trauma. 2011 Aug; 71(2 Suppl 3):S318-28.
Holcomb JB, Zarzabal LA, Michalek JE, Kozar RA, Spinella PC, Perkins JG, Matijevic N, Dong JF, Pati S, Wade CE, Trauma Outcomes Group, Holcomb JB, Wade CE, Cotton BA, Kozar RA, Brasel KJ, Vercruysse GA, MacLeod JB, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat PC, Johannigamn JA, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, DeMoya MA, Schreiber MA, Tieu BH, Brundage SI, Napolitano LM, Brunsvold ME, Sihler KC, Beilman GJ, Peitzman AB, Zenati MS, Sperry JL, Alarcon LH, Croce MA, Minei JP, Steward RM, Cohn SM, Michalek JE, Bulger EM, Nunez TC, Ivatury RR, Meredith JW, Miller PR, Pomper GJ, Marin B. PMID: 21814099.
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45 Fields:
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Humans
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Increased transforming growth factor β contributes to deterioration of refrigerated fresh frozen plasma's effects in vitro on endothelial cells. Shock. 2011 Jul; 36(1):54-9.
Duan C, Cao Y, Deng X, Wang W, Yang W, Liu X, Chen Z, Pati S, Kozar RA, Gonzalez EA, Wade CE, Holcomb JB, Ko TC. PMID: 21330944; PMCID: PMC3763495.
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PubMed Mentions:
2 Fields:
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HumansCells
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Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock. Anesth Analg. 2011 Jun; 112(6):1289-95.
Kozar RA, Peng Z, Zhang R, Holcomb JB, Pati S, Park P, Ko TC, Paredes A. PMID: 21346161; PMCID: PMC3102787.
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132 Fields:
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AnimalsCells
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Human Bone Marrow Derived Mesenchymal Stem Cells Regulate Leukocyte-Endothelial Interactions and Activation of Transcription Factor NF-Kappa B. J Tissue Sci Eng. 2011; Suppl 3:001.
Letourneau PA, Menge TD, Wataha KA, Wade CE, S Cox C, Holcomb JB, Pati S. PMID: 25309818; PMCID: PMC4189804.
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8
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Human mesenchymal stem cells inhibit vascular permeability by modulating vascular endothelial cadherin/β-catenin signaling. Stem Cells Dev. 2011 Jan; 20(1):89-101.
Pati S, Khakoo AY, Zhao J, Jimenez F, Gerber MH, Harting M, Redell JB, Grill R, Matsuo Y, Guha S, Cox CS, Reitz MS, Holcomb JB, Dash PK. PMID: 20446815; PMCID: PMC3128758.
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57 Fields:
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HumansAnimalsCells
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Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes. J Mol Cell Cardiol. 2011 Feb; 50(2):346-56.
Rogers TB, Pati S, Gaa S, Riley D, Khakoo AY, Patel S, Wardlow RD, Frederick CA, Hall G, He LP, Lederer WJ. PMID: 20837021.
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16 Fields:
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HumansAnimalsCells
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Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: preserving the blood brain barrier via an interaction with splenocytes. Exp Neurol. 2010 Oct; 225(2):341-52.
Walker PA, Shah SK, Jimenez F, Gerber MH, Xue H, Cutrone R, Hamilton JA, Mays RW, Deans R, Pati S, Dash PK, Cox CS. PMID: 20637752; PMCID: PMC3774549.
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PubMed Mentions:
76 Fields:
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AnimalsCells
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Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw. J Trauma. 2010 Jul; 69 Suppl 1:S55-63.
Pati S, Matijevic N, Doursout MF, Ko T, Cao Y, Deng X, Kozar RA, Hartwell E, Conyers J, Holcomb JB. PMID: 20622621; PMCID: PMC3126659.
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56 Fields:
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HumansAnimalsCells
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Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats. PLoS One. 2010 Jun 30; 5(6):e11383.
Dash PK, Orsi SA, Zhang M, Grill RJ, Pati S, Zhao J, Moore AN. PMID: 20614021; PMCID: PMC2894851.
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PubMed Mentions:
85 Fields:
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AnimalsCells
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Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NFkappaB-mediated increase in interleukin-6 production. Stem Cells Dev. 2010 Jun; 19(6):867-76.
Walker PA, Harting MT, Jimenez F, Shah SK, Pati S, Dash PK, Cox CS. PMID: 19775197; PMCID: PMC2891441.
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40 Fields:
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AnimalsCells
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Fresh frozen plasma increases adhesion molecule expression on human pulmonary endothelial cells. J Surg Res. 2010 Oct; 163(2):317-22.
Letourneau PA, Pati S, Gerber MH, Jimenez F, Holcomb JB. PMID: 20599210; PMCID: PMC2943032.
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PubMed Mentions:
2 Fields:
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HumansCells
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Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress. J Clin Invest. 2010 Feb; 120(2):472-84.
Chintalgattu V, Ai D, Langley RR, Zhang J, Bankson JA, Shih TL, Reddy AK, Coombes KR, Daher IN, Pati S, Patel SS, Pocius JS, Taffet GE, Buja LM, Entman ML, Khakoo AY. PMID: 20071776; PMCID: PMC2810076.
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77 Fields:
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AnimalsCells
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Intra-hippocampal administration of the VEGF receptor blocker PTK787/ZK222584 impairs long-term memory. Brain Res. 2009 Feb 23; 1256:85-91.
Pati S, Orsi SA, Moore AN, Dash PK. PMID: 19100245; PMCID: PMC2692845.
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11 Fields:
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AnimalsCells
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HIV-1 transgenic rat CD4+ T cells develop decreased CD28 responsiveness and suboptimal Lck tyrosine dephosphorylation following activation. Virology. 2006 Sep 30; 353(2):357-65.
Yadav A, Pati S, Nyugen A, Barabitskaja O, Mondal P, Anderson M, Gallo RC, Huso DL, Reid W. PMID: 16828835.
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9 Fields:
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AnimalsCells
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Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med. 2006 May 15; 203(5):1235-47.
Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, Nguyen AT, Malide D, Combs CA, Hall G, Zhang J, Raffeld M, Rogers TB, Stetler-Stevenson W, Frank JA, Reitz M, Finkel T. PMID: 16636132; PMCID: PMC2121206.
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PubMed Mentions:
326 Fields:
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AnimalsCells
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Suppression of MIP-1beta transcription in human T cells is regulated by inducible cAMP early repressor (ICER). J Leukoc Biol. 2006 Feb; 79(2):378-87.
Barabitskaja O, Foulke JS, Pati S, Bodor J, Reitz MS. PMID: 16443828.
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9 Fields:
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HumansCells
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Tumorigenesis by human herpesvirus 8 vGPCR is accelerated by human immunodeficiency virus type 1 Tat. J Virol. 2004 Sep; 78(17):9336-42.
Guo HG, Pati S, Sadowska M, Charurat M, Reitz M. PMID: 15308728; PMCID: PMC506953.
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23 Fields:
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AnimalsCells
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Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat. J Virol. 2003 May; 77(10):5759-73.
Pati S, Foulke JS, Barabitskaya O, Kim J, Nair BC, Hone D, Smart J, Feldman RA, Reitz M. PMID: 12719569; PMCID: PMC154031.
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PubMed Mentions:
27 Fields:
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HumansCells
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Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi sarcoma. Blood. 2002 May 15; 99(10):3771-9.
Pati S, Pelser CB, Dufraine J, Bryant JL, Reitz MS, Weichold FF. PMID: 11986235.
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39 Fields:
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HumansAnimalsCells
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Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis. J Virol. 2001 Sep; 75(18):8660-73.
Pati S, Cavrois M, Guo HG, Foulke JS, Kim J, Feldman RA, Reitz M. PMID: 11507211; PMCID: PMC115111.
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PubMed Mentions:
67 Fields:
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HumansCells
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Human herpesvirus 8 K1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi's sarcoma inflammation? J Natl Cancer Inst Monogr. 2001; (28):15-23.
Samaniego F, Pati S, Karp JE, Prakash O, Bose D. PMID: 11158202.
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31 Fields:
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HumansAnimalsCells
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Urinary proteins with pro-apoptotic and antitumor activity. Apoptosis. 2000 Feb; 5(1):21-8.
Pati S, Lee Y, Samaniego F. PMID: 11227487.
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Humans
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HIV-1 protease inhibitor ritonavir modulates susceptibility to apoptosis of uninfected T cells. J Hum Virol. 1999 Sep-Oct; 2(5):261-9.
Weichold FF, Bryant JL, Pati S, Barabitskaya O, Gallo RC, Reitz MS. PMID: 10551732.
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PubMed Mentions:
14 Fields:
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HumansCells
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Gain of function mutations in p53. Nat Genet. 1993 May; 4(1):42-6.
Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C, Levine AJ. PMID: 8099841.
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PubMed Mentions:
306 Fields:
Translation:
HumansAnimalsCells