Manju Sharma, PhD

Photo of Manju Sharma, PhD
Title(s)Associate Professor, Radiation Oncology
SchoolSchool of Medicine
ORCID ORCID Icon0000-0003-0021-1265 Additional info
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    Collapse Biography 
    Collapse education and training
    University of California, San Francisco, CA2022Diversity, Equity, and Inclusion Champion Training
    Collapse awards and honors
    Department of Radiation Oncology, University of California, San Francisco2025Jean Pouliot Teaching Award
    International Conference on Medical Physics in Radiation Oncology and Imaging (ICMPROI-2025), 13-15 2025Guest of Honor
    International Medical Physics Symposium, 11 November 2022, Panjab University, Chandigarh, India2022Guest of Honor
    55th Annual AAPM Meeting2013Research "HOT TOPIC" article
    European Society for Therapeutic Radiology and Oncology newsletter2013Featured Research Article
    American College of Rheumatology2012Research included in the clinical guidelines
    Medical Physics Web2012Featured Research Innovation
    Department of Science and Technology (DST), India2005International Travel Grant
    Indian National Science Academy (INSA), India2005International Travel Grant
    Indian National Science Academy (INSA), India2005International Travel Grant
    Council of Scientific and Industrial Research (CSIR), India2004Commendable Scientific Writing
    Council of Scientific and Industrial Research (CSIR), India2004Senior Research Fellowship

    Collapse Research 
    Collapse Featured Publications
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    Impact of breast tissue expanders in the post-mastectomy radiation treatment (PMRT) clinical validation and treatment workflow.
    Sientra Inc CA-0160869Jul 1, 2022 - Jul 30, 2023
    Description: Additional validation and testing on novel breast tissue expanders before the FDA Clearance AlloX2 Pro™
    Cone Beam CT Image Analysis to Predict Head and Neck Radiotherapy Toxicities for Adaptive Radiotherapy
    UCSF RAP CA-0213350Jul 1, 2021 - Jun 30, 2023
    Role: PI
    Description: To develop a user-friendly CBCT-based rapid and personalized assessment of anatomy changes during HNRT. This frequent assessment could alert physicians to make changes and adapt the radiation plan earlier during treatment, before acute toxicities occur.
    Impact of breast tissue expanders in the post-mastectomy radiation treatment (PMRT) clinical validation and treatment workflow
    Sientra Inc CA-01608692Jun 1, 2021 - Jul 30, 2022
    Role: PI
    Description: The goal of the study is to provide guidance on the design of novel breast metal port expanders, AlloX2 Pro™, and to compare it with AlloX2 for patients receiving Post-mastectomy breast irradiation.

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    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. GTV Expert Opinion: The Past Is Part of the Prescription: Spatially Aware Cumulative Dose Assessment for Complex Reirradiation. Radiother Oncol. 2026 Sep; 222:111584. Sharma M, Paradis KC. PMID: 42603725.
      View in: PubMed   Mentions:
    2. Reirradiation for recurrent head and neck squamous cell carcinoma: international expert consensus recommendations endorsed by the Reirradiation Collaborative Group, the European Society for Radiotherapy and Oncology Reirradiation Focus Group, and the American Society for Radiation Oncology. Lancet Oncol. 2026 Jul; 27(7):e350-e361. Biau J, Beddok A, Sharma M, Malik N, Ghosh Laskar S, Cacicedo J, Embring A, Nuyts S, Mayo C, Paradis KC, Ward MC, Bonomo P, Gan GN, Bahl A, Balermpas P, Chua MLK, Popovtzer A, Simone CB, Vasquez Osorio E, Yom SS, Blanchard P, Reirradiation Collaborative Group (ReCOG) and ESTRO Reirradiation Focus Group Collaborators. PMID: 42372755.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Breast Cancer Reirradiation Practice Patterns: An International Survey From the Reirradiation Collaborative Group (ReCOG). Pract Radiat Oncol. 2026 May 27. Hong L, Poortmans P, Aznar M, Brooks ED, Casey D, Choi JI, Corradini S, Jagsi R, Keilty D, Koch A, Kronborg C, Kubeczko M, McClatchy D, Popovic M, Salerno KE, Shaitelman SF, Sharma M, Tsang Y, Mayo C, Gabrys D. PMID: 42207068; PMCID: PMC13220910.
      View in: PubMed   Mentions:    Fields:    
    4. Where Anatomy Decides and Feasibility Ends. Int J Radiat Oncol Biol Phys. 2026 Mar 15; 124(4):894. Menghini A, Sharma M. PMID: 41741088.
      View in: PubMed   Mentions:    Fields:    
    5. Global Dose Prescription Variances Exemplified Through Oropharynx Cancer: When Is 70 Gray 70 Gray? Int J Radiat Oncol Biol Phys. 2026 Jul 15; 125(4):1252-1257. Hansen CR, Tadic T, Sharma M, Price G, Petersen J, Naser MA, Xiao Y, Kovalchuk N, Lassen P, Overgaard J, McDowell L, Ramachandran P, Kim JW, Fuller CD, Thomson DJ, Johansen J, Friborg J, Yom SS, Hope A. PMID: 41628865.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Reirradiation clinical practice in gastrointestinal abdominal malignancies: an international reirradiation collaborative group (ReCOG) systematic review. Clin Transl Radiat Oncol. 2025 Nov; 55:101033. Malik NH, Plastaras JP, Corradini S, Dawson LA, Hawkins MA, Salerno KE, Mayo CS, Dunne EM, Gabrys D, Grassberger C, Lawrence TS, Sharma M, Bergman AM, Owen D, Zaila A, Rudra S, Velec M, Murrell DH. PMID: 40895774; PMCID: PMC12391431.
      View in: PubMed   Mentions:
    7. Physical contributors to dose in patients with dual-port temporary tissue expanders treated post-mastectomy with 10 MV x-rays: a Monte Carlo study. Biomed Phys Eng Express. 2025 Apr 25; 11(3). Ortiz R, Faddegon B, Sharma M, Ramos-Méndez J. PMID: 40245878; PMCID: PMC12128857.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Outcomes and dosimetric analysis of reirradiation of oral cavity and oropharyngeal cancers with high-dose-rate brachytherapy. Brachytherapy. 2025 May-Jun; 24(3):413-419. Phuong C, Ni L, Sharma M, Cunha JAM, Yom SS, Hsu IC, Chan JW. PMID: 40118709.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Does Time to Retreatment Matter? A Normal Tissue Complication Probability Model to Predict Radionecrosis After Repeat Stereotactic Radiosurgery for Recurrent Brain Metastases Incorporating Time-dependent Discounted Dose. Int J Radiat Oncol Biol Phys. 2025 06 01; 122(2):467-475. Sharma M, Naqa IE, Sneed PK. PMID: 39900228.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    10. Corrigendum: DiffuseRT: predicting likely anatomical deformations of patients undergoing radiotherapy (2024Phys. Med. Biol. 69 155016). Phys Med Biol. 2024 Dec 24; 70(1). Smolders A, Rivetti L, Vatterodt N, Korreman S, Lomax A, Sharma M, Studen A, Weber DC, Jeraj R, Albertini F. PMID: 39728405.
      View in: PubMed   Mentions:    Fields:    
    11. DiffuseRT: predicting likely anatomical deformations of patients undergoing radiotherapy. Phys Med Biol. 2024 07 22; 69(15). Smolders A, Rivetti L, Vatterodt N, Korreman S, Lomax A, Sharma M, Studen A, Weber DC, Jeraj R, Albertini F. PMID: 38986481.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. Uncertainty estimation and evaluation of deformation image registration based convolutional neural networks. Phys Med Biol. 2024 05 30; 69(11). Rivetti L, Studen A, Sharma M, Chan J, Jeraj R. PMID: 38749468.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. The structure of a hibernating ribosome in a Lyme disease pathogen. Nat Commun. 2023 10 31; 14(1):6961. Sharma MR, Manjari SR, Agrawal EK, Keshavan P, Koripella RK, Majumdar S, Marcinkiewicz AL, Lin YP, Agrawal RK, Banavali NK. PMID: 37907464; PMCID: PMC10618245.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    14. Framework for Quality Assurance of Ultrahigh Dose Rate Clinical Trials Investigating FLASH Effects and Current Technology Gaps. Int J Radiat Oncol Biol Phys. 2023 08 01; 116(5):1202-1217. Zou W, Zhang R, Schüler E, Taylor PA, Mascia AE, Diffenderfer ES, Zhao T, Ayan AS, Sharma M, Yu SJ, Lu W, Bosch WR, Tsien C, Surucu M, Pollard-Larkin JM, Schuemann J, Moros EG, Bazalova-Carter M, Gladstone DJ, Li H, Simone CB, Petersson K, Kry SF, Maity A, Loo BW, Dong L, Maxim PG, Xiao Y, Buchsbaum JC. PMID: 37121362; PMCID: PMC10526970.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    15. Dosimetric characterization of single- and dual-port temporary tissue expanders for postmastectomy radiotherapy using Monte Carlo methods. Front Oncol. 2023; 13:1124838. Ramos-Méndez J, Park C, Sharma M. PMID: 37143943; PMCID: PMC10151677.
      View in: PubMed   Mentions: 2  
    16. Tumor Control Probability After Radiosurgery of Brain Metastases With and Without Retreatment. Int J Radiat Oncol Biol Phys. 2022 11 01; 114(3):537-544. Sharma M, Milano MT, Cummings M, Naqa IE. PMID: 35863671.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. A systematic review and meta-analysis of liver tumor position variability during SBRT using various motion management and IGRT strategies. Radiother Oncol. 2022 01; 166:195-202. Sharma M, Nano TF, Akkati M, Milano MT, Morin O, Feng M. PMID: 34843841.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    18. Rectal spacing, prostate coverage, and periprocedural outcomes after hydrogel spacer injection during low-dose-rate brachytherapy implantation. Brachytherapy. 2020 Mar - Apr; 19(2):228-233. Kahn J, Dahman B, McLaughlin C, Kapoor P, Kapoor R, Harris E, Sharma M, Schutzer M, Moghanaki D. PMID: 32085930.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    19. Structure of Human Mitochondrial Translation Initiation Factor 3 Bound to the Small Ribosomal Subunit. iScience. 2019 Feb 22; 12:76-86. Koripella RK, Sharma MR, Haque ME, Risteff P, Spremulli LL, Agrawal RK. PMID: 30677741; PMCID: PMC6352543.
      View in: PubMed   Mentions: 25  
    20. Single-Fraction Radiosurgery Using Conservative Doses for Brain Metastases: Durable Responses in Select Primaries With Limited Toxicity. Neurosurgery. 2018 09 01; 83(3):437-444. Cummings M, Youn P, Bergsma DP, Usuki KY, Walter K, Sharma M, Okunieff P, Schell MC, Milano MT. PMID: 28945885.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    21. Radiation-Induced Edema After Single-Fraction or Multifraction Stereotactic Radiosurgery for Meningioma: A Critical Review. Int J Radiat Oncol Biol Phys. 2018 06 01; 101(2):344-357. Milano MT, Sharma M, Soltys SG, Sahgal A, Usuki KY, Saenz JM, Grimm J, El Naqa I. PMID: 29726362.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    22. Clinically relevant investigation of flattening filter-free skin dose. J Appl Clin Med Phys. 2016 11 08; 17(6):140-148. Guy CL, Karki K, Sharma M, Kim S. PMID: 27929489; PMCID: PMC5690509.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    23. Erratum: "Coverage-based treatment planning to accommodate deformable organ variations in prostate cancer treatment" [Med. Phys. 41(10), 101705 (14pp.) (2014)]. Med Phys. 2016 06; 43(6):3206. Xu H, Vile DJ, Sharma M, Gordon JJ, Siebers JV. PMID: 27277064; PMCID: PMC4902805.
      View in: PubMed   Mentions:    Fields:    
    24. A novel two-step optimization method for tandem and ovoid high-dose-rate brachytherapy treatment for locally advanced cervical cancer. Brachytherapy. 2015 Sep-Oct; 14(5):613-8. Sharma M, Fields EC, Todor DA. PMID: 26092424.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    25. Coverage-based treatment planning to accommodate deformable organ variations in prostate cancer treatment. Med Phys. 2014 Oct; 41(10):101705. Xu H, Vile DJ, Sharma M, Gordon JJ, Siebers JV. PMID: 25281944; PMCID: PMC4290467.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    26. The influence of therapeutic radiation on the patterns of bone remodeling in ovary-intact and ovariectomized mice. Calcif Tissue Int. 2013 Apr; 92(4):372-84. Hui SK, Fairchild GR, Kidder LS, Sharma M, Bhattacharya M, Jackson S, Le C, Petryk A, Islam MS, Yee D. PMID: 23314741; PMCID: PMC3595353.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    27. Dose deformation-invariance in adaptive prostate radiation therapy: implication for treatment simulations. Radiother Oncol. 2012 Nov; 105(2):207-13. Sharma M, Weiss E, Siebers JV. PMID: 23200409; PMCID: PMC6559364.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    28. Skeletal remodeling following clinically relevant radiation-induced bone damage treated with zoledronic acid. Calcif Tissue Int. 2012 Jan; 90(1):40-9. Hui SK, Fairchild GR, Kidder LS, Sharma M, Bhattacharya M, Jackson S, Le C, Yee D. PMID: 22083107.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsPHPublic Health
    29. Feasibility of intrafraction whole-body motion tracking for total marrow irradiation. J Biomed Opt. 2011 May; 16(5):058002. Sharma M, Dos Santos T, Papanikolopoulos NP, Hui SK. PMID: 21639586; PMCID: PMC3113335.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Development of 41Ca-based pharmacokinetic model for the study of bone remodelling in humans. Clin Pharmacokinet. 2011 Mar; 50(3):191-9. Sharma M, Bajzer Z, Hui SK. PMID: 21294596.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    31. Photochemical reactions of surfactant molecules in condensed monolayer assemblies--environmental control and modification of reactivity. Angew Chem Int Ed Engl. 1979 Jun; 18(6):440-50. Whitten DG. PMID: 111584.
      View in: PubMed   Mentions:    Fields:    
    32. Calcium transport driven by a proton gradient and inverted membrane vesicles of Escherichia coli. J Biol Chem. 1976 Feb 25; 251(4):962-7. Tsuchiya T, Rosen BP. PMID: 2608.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    33. A comparison of the substrate specificities of endo-beta-N-acetylglucosaminidases from Streptomyces griseus and Diplococcus Pneumoniae. Biochem Biophys Res Commun. 1975 Nov 03; 67(1):455-62. Tarentino AL, Maley F. PMID: 1016.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    34. [Changes in the indicators of immunologic reactivity in patients with juvenile uterine hemorrhages in different methods of therapy]. Akush Ginekol (Mosk). 1975 Oct; (10):29-31. Poliak SSh. PMID: 2026.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Digitoxin metabolism by rat liver microsomes. Biochem Pharmacol. 1975 Sep 01; 24(17):1639-41. Schmoldt A, Benthe HF, Haberland G. PMID: 10.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    36. Bacteriologic flora of aspiration-induced pulmonary infections. Arch Intern Med. 1975 May; 135(5):711-4. Cesar L, Gonzalez C, Calia FM. PMID: 28705.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    37. Radiation damage in stained catalase at low temperature. J Microsc. 1975 Mar; 103(2):209-14. Glaeser RM, Hobbs LW. PMID: 48550.
      View in: PubMed   Mentions:    Fields:    
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