Nadia Arang, PhD

Title(s)Postdoctoral Scholar, Quantitative_Bioscience_Ins
SchoolSchool of Pharmacy
Address1700 4th Street, #309
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Using machine learning to dissect host kinases required for Leishmania internalization and development. Mol Biochem Parasitol. 2024 Aug 22; 260:111651. Wei L, Barrie U, Aloisio GM, Khuong FTH, Arang N, Datta A, Kaushansky A, Wetzel DM. PMID: 39181505.
      View in: PubMed   Mentions:    Fields:    
    2. Using machine learning to dissect host kinases required for Leishmania internalization and development. bioRxiv. 2024 Aug 04. Wei L, Barrie U, Aloisio GM, Khuong FTH, Arang N, Datta A, Kaushansky A, Wetzel DM. PMID: 38798624; PMCID: PMC11118464.
      View in: PubMed   Mentions:
    3. Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation. NPJ Syst Biol Appl. 2024 Jul 16; 10(1):75. Trogdon M, Abbott K, Arang N, Lande K, Kaur N, Tong M, Bakhoum M, Gutkind JS, Stites EC. PMID: 39013872; PMCID: PMC11252164.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC. Cancer Res Commun. 2024 Jul 01; 4(7):1850-1862. Goto Y, Koshizuka K, Ando T, Izumi H, Wu X, Sato K, Ishikawa T, Ford K, Feng X, Wang Z, Arang N, Allevato MM, Kishore A, Mali P, Gutkind JS. PMID: 38954773; PMCID: PMC11284272.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule. Nat Cancer. 2024 Jul; 5(7):1082-1101. Kelly LM, Rutter JC, Lin KH, Ling F, Duchmann M, Latour E, Arang N, Pasquer H, Ho Nhat D, Charles J, Killarney ST, Ang HX, Namor F, Culeux C, Lombard B, Loew D, Swaney DL, Krogan NJ, Brunel L, Carretero É, Verdié P, Amblard M, Fodil S, Huynh T, Sebert M, Adès L, Raffoux E, Fenouille N, Itzykson R, Lobry C, Benajiba L, Forget A, Martin AR, Wood KC, Puissant A. PMID: 38816660.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma. Cell Rep Med. 2023 11 21; 4(11):101244. Arang N, Lubrano S, Ceribelli M, Rigiracciolo DC, Saddawi-Konefka R, Faraji F, Ramirez SI, Kim D, Tosto FA, Stevenson E, Zhou Y, Wang Z, Bogomolovas J, Molinolo AA, Swaney DL, Krogan NJ, Yang J, Coma S, Pachter JA, Aplin AE, Alessi DR, Thomas CJ, Gutkind JS. PMID: 37858338; PMCID: PMC10694608.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    7. Catalytic site mutations confer multiple states of G protein activation. Sci Signal. 2023 02 14; 16(772):eabq7842. Hewitt N, Ma N, Arang N, Martin SA, Prakash A, DiBerto JF, Knight KM, Ghosh S, Olsen RHJ, Roth BL, Gutkind JS, Vaidehi N, Campbell SL, Dohlman HG. PMID: 36787384; PMCID: PMC10021883.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    8. Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ-focal adhesion kinase signaling circuitry. J Biol Chem. 2023 02; 299(2):102866. Arang N, Lubrano S, Rigiracciolo DC, Nachmanson D, Lippman SM, Mali P, Harismendy O, Gutkind JS. PMID: 36596361; PMCID: PMC9922814.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    9. A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection. Cell Chem Biol. 2022 09 15; 29(9):1419-1433.e5. Vijayan K, Arang N, Wei L, Morrison R, Geiger R, Parks KR, Lewis AJ, Mast FD, Douglass AN, Kain HS, Aitchison JD, Johnson JS, Aderem A, Kaushansky A. PMID: 35738280; PMCID: PMC9481707.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    10. Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC). J Exp Clin Cancer Res. 2022 Jun 03; 41(1):193. Rigiracciolo DC, Nohata N, Lappano R, Cirillo F, Talia M, Adame-Garcia SR, Arang N, Lubrano S, De Francesco EM, Belfiore A, Gutkind JS, Maggiolini M. PMID: 35655319; PMCID: PMC9164429.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    11. Cyclosporine Induces Fenestra-Associated Injury in Human Renal Microvessels In Vitro. ACS Biomater Sci Eng. 2022 01 10; 8(1):196-207. Nagao RJ, Marcu R, Shin YJ, Lih D, Xue J, Arang N, Wei L, Akilesh S, Kaushansky A, Himmelfarb J, Zheng Y. PMID: 34927415.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    12. EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1. Commun Biol. 2021 11 01; 4(1):1237. Ando T, Arang N, Wang Z, Costea DE, Feng X, Goto Y, Izumi H, Gilardi M, Ando K, Gutkind JS. PMID: 34725466; PMCID: PMC8560880.
      View in: PubMed   Mentions: 18  Translation:AnimalsCells
    13. Gαs-Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling. Pharmacol Rev. 2021 10; 73(4):155-197. Ramms DJ, Raimondi F, Arang N, Herberg FW, Taylor SS, Gutkind JS. PMID: 34663687; PMCID: PMC11060502.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    14. Correction: Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma. Clin Cancer Res. 2021 Aug 15; 27(16):4664. Paradis JS, Acosta M, Saddawi-Konefka R, Kishore A, Lubrano S, Gomes F, Arang N, Tiago M, Coma S, Wu X, Ford K, Day CP, Merlino G, Mali P, Pachter JA, Sato T, Aplin AE, Gutkind JS. PMID: 34389658.
      View in: PubMed   Mentions: 1     Fields:    
    15. Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma. Clin Cancer Res. 2021 06 01; 27(11):3190-3200. Paradis JS, Acosta M, Saddawi-Konefka R, Kishore A, Gomes F, Arang N, Tiago M, Coma S, Lubrano S, Wu X, Ford K, Day CP, Merlino G, Mali P, Pachter JA, Sato T, Aplin AE, Gutkind JS. PMID: 33568347; PMCID: PMC8895627.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    16. G Protein-Coupled receptors and heterotrimeric G proteins as cancer drivers. FEBS Lett. 2020 12; 594(24):4201-4232. Arang N, Gutkind JS. PMID: 33270228; PMCID: PMC8849590.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    17. Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis. Oncogene. 2020 05; 39(20):4014-4027. Goto Y, Ando T, Izumi H, Feng X, Arang N, Gilardi M, Wang Z, Ando K, Gutkind JS. PMID: 32205868; PMCID: PMC7428076.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    18. Illuminating G-Protein-Coupling Selectivity of GPCRs. Cell. 2019 06 13; 177(7):1933-1947.e25. Inoue A, Raimondi F, Kadji FMN, Singh G, Kishi T, Uwamizu A, Ono Y, Shinjo Y, Ishida S, Arang N, Kawakami K, Gutkind JS, Aoki J, Russell RB. PMID: 31160049; PMCID: PMC6773469.
      View in: PubMed   Mentions: 231     Fields:    Translation:HumansCells
    19. Liver stage malaria infection is controlled by host regulators of lipid peroxidation. Cell Death Differ. 2020 01; 27(1):44-54. Kain HS, Glennon EKK, Vijayan K, Arang N, Douglass AN, Fortin CL, Zuck M, Lewis AJ, Whiteside SL, Dudgeon DR, Johnson JS, Aderem A, Stevens KR, Kaushansky A. PMID: 31065106; PMCID: PMC7206113.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    20. Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection. Cell Rep. 2019 03 19; 26(12):3391-3399.e4. Glennon EKK, Austin LS, Arang N, Kain HS, Mast FD, Vijayan K, Aitchison JD, Kappe SHI, Kaushansky A. PMID: 30893610; PMCID: PMC6447308.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    21. Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential. Sci Signal. 2019 02 19; 12(569). Bandekar SJ, Arang N, Tully ES, Tang BA, Barton BL, Li S, Gutkind JS, Tesmer JJG. PMID: 30783010; PMCID: PMC6519057.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    22. A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK. Cancer Cell. 2019 03 18; 35(3):457-472.e5. Feng X, Arang N, Rigiracciolo DC, Lee JS, Yeerna H, Wang Z, Lubrano S, Kishore A, Pachter JA, König GM, Maggiolini M, Kostenis E, Schlaepfer DD, Tamayo P, Chen Q, Ruppin E, Gutkind JS. PMID: 30773340; PMCID: PMC6737937.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    23. Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles. Nat Commun. 2017 11 01; 8(1):1232. Arang N, Kain HS, Glennon EK, Bello T, Dudgeon DR, Walter ENF, Gujral TS, Kaushansky A. PMID: 29089541; PMCID: PMC5663700.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    24. Malaria parasites target the hepatocyte receptor EphA2 for successful host infection. Science. 2015 Nov 27; 350(6264):1089-92. Kaushansky A, Douglass AN, Arang N, Vigdorovich V, Dambrauskas N, Kain HS, Austin LS, Sather DN, Kappe SH. PMID: 26612952; PMCID: PMC4783171.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    25. Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites. Mol Ther. 2015 May; 23(5):857-865. Douglass AN, Kain HS, Abdullahi M, Arang N, Austin LS, Mikolajczak SA, Billman ZP, Hume JCC, Murphy SC, Kappe SHI, Kaushansky A. PMID: 25648263; PMCID: PMC4427874.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    26. Susceptibility to Plasmodium yoelii preerythrocytic infection in BALB/c substrains is determined at the point of hepatocyte invasion. Infect Immun. 2015 Jan; 83(1):39-47. Kaushansky A, Austin LS, Mikolajczak SA, Lo FY, Miller JL, Douglass AN, Arang N, Vaughan AM, Gardner MJ, Kappe SH. PMID: 25312960; PMCID: PMC4288894.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    27. SSP3 is a novel Plasmodium yoelii sporozoite surface protein with a role in gliding motility. Infect Immun. 2014 Nov; 82(11):4643-53. Harupa A, Sack BK, Lakshmanan V, Arang N, Douglass AN, Oliver BG, Stuart AB, Sather DN, Lindner SE, Hybiske K, Torii M, Kappe SH. PMID: 25156733; PMCID: PMC4249349.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
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