Kirsten Obernier, PhD

Title(s)Specialist, Quantitative_Bioscience_Ins
SchoolSchool of Pharmacy
Address1700 4th St
San Francisco CA 94158
Phone415-476-2980
EmailKirsten.Obernier@ucsf.edu
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    Collapse Biography 
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    University of California, San FranciscoPostdoctoral StudiesNeurosurgery
    University of HeidelbergPh.D.2010Neurobiology

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Target Discovery for Host-Directed Antiviral Therapies: Application of Proteomics Approaches. mSystems. 2021 Sep 14; e0038821. Cakir M, Obernier K, Forget A, Krogan NJ. PMID: 34519533.
      View in: PubMed   Mentions:
    2. Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenesis. Elife. 2021 07 14; 10. Cebrian-Silla A, Nascimento MA, Redmond SA, Mansky B, Wu D, Obernier K, Romero Rodriguez R, Gonzalez-Granero S, García-Verdugo JM, Lim DA, Álvarez-Buylla A. PMID: 34259628.
      View in: PubMed   Mentions: 1     Fields:    
    3. Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant. bioRxiv. 2021 Jun 07. Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Ummadi M, Rojc A, Turner J, Obernier K, Braberg H, Soucheray M, Richards A, Chen KH, Harjai B, Memon D, Hosmillo M, Hiatt J, Jahun A, Goodfellow IG, Fabius JM, Shokat K, Jura N, Verba K, Noursadeghi M, Beltrao P, Swaney DL, Garcia-Sastre A, Jolly C, Towers GJ, Krogan NJ. PMID: 34127972.
      View in: PubMed   Mentions:
    4. Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization. medRxiv. 2021 May 25. Varona JF, Landete P, Lopez-Martin JA, Estrada V, Paredes R, Guisado-Vasco P, de Orueta LF, Torralba M, Fortún J, Vates R, Barberán J, Clotet B, Ancochea J, Carnevali D, Cabello N, Porras L, Gijón P, Monereo A, Abad D, Zúñiga S, Sola I, Rodon J, Izquierdo-Useros N, Fudio S, Pontes MJ, de Rivas B, Girón de Velasco P, Sopesén B, Nieto A, Gómez J, Avilés P, Lubomirov R, White KM, Rosales R, Yildiz S, Reuschl AK, Thorne LG, Jolly C, Towers GJ, Zuliani-Alvarez L, Bouhaddou M, Obernier K, Enjuanes L, Fernández-Sousa JM, Plitidepsin – COVID - 19 Study Group , Krogan NJ, Jimeno JM, García-Sastre A. PMID: 34075384.
      View in: PubMed   Mentions:
    5. Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant. bioRxiv. 2021 Feb 04. Reuschl AK, Thorne LG, Zuliani-Alvarez L, Bouhaddou M, Obernier K, Hiatt J, Soucheray M, Turner J, Fabius JM, Nguyen GT, Swaney DL, Rosales R, White KM, Avilés P, Kirby IT, Melnyk JE, Shi Y, Zhang Z, Shokat KM, García-Sastre A, Jolly C, Towers GJ, Krogan NJ. PMID: 33501437.
      View in: PubMed   Mentions:
    6. Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A. Science. 2021 02 26; 371(6532):926-931. White KM, Rosales R, Yildiz S, Kehrer T, Miorin L, Moreno E, Jangra S, Uccellini MB, Rathnasinghe R, Coughlan L, Martinez-Romero C, Batra J, Rojc A, Bouhaddou M, Fabius JM, Obernier K, Dejosez M, Guillén MJ, Losada A, Avilés P, Schotsaert M, Zwaka T, Vignuzzi M, Shokat KM, Krogan NJ, García-Sastre A. PMID: 33495306.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    7. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020 08 06; 182(3):685-712.e19. Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, Hüttenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu J, Bouhaddou S, Mathy CJP, Gaulton A, Manners EJ, Félix E, Shi Y, Goff M, Lim JK, McBride T, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, De Wit E, Leach AR, Kortemme T, Shoichet B, Ott M, Saez-Rodriguez J, tenOever BR, Mullins RD, Fischer ER, Kochs G, Grosse R, García-Sastre A, Vignuzzi M, Johnson JR, Shokat KM, Swaney DL, Beltrao P, Krogan NJ. PMID: 32645325.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    8. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020 07; 583(7816):459-468. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, García-Sastre A, Shokat KM, Shoichet BK, Krogan NJ. PMID: 32353859.
      View in: PubMed   Mentions: 1008     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    9. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. bioRxiv. 2020 Mar 22. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Naing ZZC, Zhou Y, Peng S, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Shen W, Shi Y, Zhang Z, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Ramachandran R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Lin Y, Wankowicz SA, Bohn M, Trenker R, Young JM, Cavero D, Hiatt J, Roth T, Rathore U, Subramanian A, Noack J, Hubert M, Roesch F, Vallet T, Meyer B, White KM, Miorin L, Agard D, Emerman M, Ruggero D, García-Sastre A, Jura N, von Zastrow M, Taunton J, Schwartz O, Vignuzzi M, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor S, Fraser JS, Gross J, Sali A, Kortemme T, Beltrao P, Shokat K, Shoichet BK, Krogan NJ. PMID: 32511329.
      View in: PubMed   Mentions:
    10. Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor. Cell Rep. 2019 04 09; 27(2):429-441.e3. Redmond SA, Figueres-Oñate M, Obernier K, Nascimento MA, Parraguez JI, López-Mascaraque L, Fuentealba LC, Alvarez-Buylla A. PMID: 30970247.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    11. Neural stem cells: origin, heterogeneity and regulation in the adult mammalian brain. Development. 2019 02 18; 146(4). Obernier K, Alvarez-Buylla A. PMID: 30777863.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    12. A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma. Nat Cell Biol. 2018 10; 20(10):1203-1214. Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM. PMID: 30202050.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    13. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell. 2018 05 14; 33(5):874-889.e7. Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, Ghosh M, Tirosh I, Huillard E, Alvarez-Buylla A, Oldham MC, Persson AI, Weiss WA, Batchelor TT, Stemmer-Rachamimov A, Suvà ML, Phillips JJ, Aghi MK, Mehta S, Jain RK, Rowitch DH. PMID: 29681511.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    14. Adult Neurogenesis Is Sustained by Symmetric Self-Renewal and Differentiation. Cell Stem Cell. 2018 02 01; 22(2):221-234.e8. Obernier K, Cebrian-Silla A, Thomson M, Parraguez JI, Anderson R, Guinto C, Rodas Rodriguez J, Garcia-Verdugo JM, Alvarez-Buylla A. PMID: 29395056.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    15. Embryonic Origin of Postnatal Neural Stem Cells. Cell. 2015 Jun 18; 161(7):1644-55. Fuentealba LC, Rompani SB, Parraguez JI, Obernier K, Romero R, Cepko CL, Alvarez-Buylla A. PMID: 26091041.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    16. Primary cilia are required in a unique subpopulation of neural progenitors. Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34):12438-43. Tong CK, Han YG, Shah JK, Obernier K, Guinto CD, Alvarez-Buylla A. PMID: 25114218.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    17. Restricted nature of adult neural stem cells: re-evaluation of their potential for brain repair. Front Neurosci. 2014; 8:162. Obernier K, Tong CK, Alvarez-Buylla A. PMID: 24987325.
      View in: PubMed   Mentions:
    18. An evaluation of the sensitivity of MRI at detecting hepatocellular carcinoma in cirrhotic patients utilizing an explant reference standard. Clin Imaging. 2014 Sep-Oct; 38(5):693-7. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR. PMID: 33060197.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    19. Axonal control of the adult neural stem cell niche. Cell Stem Cell. 2014 Apr 03; 14(4):500-11. Tong CK, Chen J, Cebrián-Silla A, Mirzadeh Z, Obernier K, Guinto CD, Tecott LH, García-Verdugo JM, Kriegstein A, Alvarez-Buylla A. PMID: 24561083.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    20. Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ. Sci Rep. 2014 Jan 22; 4:3803. Khatri P, Obernier K, Simeonova IK, Hellwig A, Hölzl-Wenig G, Mandl C, Scholl C, Wölfl S, Winkler J, Gaspar JA, Sachinidis A, Ciccolini F. PMID: 24448162.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. Molecular diversity subdivides the adult forebrain neural stem cell population. Stem Cells. 2014 Jan; 32(1):70-84. Giachino C, Basak O, Lugert S, Knuckles P, Obernier K, Fiorelli R, Frank S, Raineteau O, Alvarez-Buylla A, Taylor V. PMID: 23964022.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    22. Lineage progression from stem cells to new neurons in the adult brain ventricular-subventricular zone. . 2013 Jun 01; 12(11):1649-50. Ponti G, Obernier K, Alvarez-Buylla A. PMID: 23673324.
      View in: PubMed   Mentions:
    23. Cell cycle and lineage progression of neural progenitors in the ventricular-subventricular zones of adult mice. Proc Natl Acad Sci U S A. 2013 Mar 12; 110(11):E1045-54. Ponti G, Obernier K, Guinto C, Jose L, Bonfanti L, Alvarez-Buylla A. PMID: 23431204.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    24. Adult neural stem cells bridge their niche. Cell Stem Cell. 2012 Jun 14; 10(6):698-708. Fuentealba LC, Obernier K, Alvarez-Buylla A. PMID: 22704510.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansCells
    25. Expression of Tlx in both stem cells and transit amplifying progenitors regulates stem cell activation and differentiation in the neonatal lateral subependymal zone. Stem Cells. 2011 Sep; 29(9):1415-26. Obernier K, Simeonova I, Fila T, Mandl C, Hölzl-Wenig G, Monaghan-Nichols P, Ciccolini F. PMID: 21714038.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    26. GABAA receptor signaling induces osmotic swelling and cell cycle activation of neonatal prominin+ precursors. Stem Cells. 2011 Feb; 29(2):307-19. Cesetti T, Fila T, Obernier K, Bengtson CP, Li Y, Mandl C, Hölzl-Wenig G, Ciccolini F. PMID: 21732488.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    27. Multipotent precursors in the anterior and hippocampal subventricular zone display similar transcription factor signatures but their proliferation and maintenance are differentially regulated. Mol Cell Neurosci. 2010 Aug; 44(4):318-29. Carrillo-García C, Suh Y, Obernier K, Hölzl-Wenig G, Mandl C, Ciccolini F. PMID: 20417282.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    28. Interaction between DLX2 and EGFR regulates proliferation and neurogenesis of SVZ precursors. Mol Cell Neurosci. 2009 Dec; 42(4):308-14. Suh Y, Obernier K, Hölzl-Wenig G, Mandl C, Herrmann A, Wörner K, Eckstein V, Ciccolini F. PMID: 19683576.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    29. Analysis of stem cell lineage progression in the neonatal subventricular zone identifies EGFR+/NG2- cells as transit-amplifying precursors. Stem Cells. 2009 Jun; 27(6):1443-54. Cesetti T, Obernier K, Bengtson CP, Fila T, Mandl C, Hölzl-Wenig G, Wörner K, Eckstein V, Ciccolini F. PMID: 19489104.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    30. Functional characterization and transcriptome analysis of embryonic stem cell-derived contractile smooth muscle cells. Hypertension. 2009 Feb; 53(2):196-204. Potta SP, Liang H, Pfannkuche K, Winkler J, Chen S, Doss MX, Obernier K, Kamisetti N, Schulz H, Hübner N, Hescheler J, Sachinidis A. PMID: 19064816.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
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