Zachary Steinhart, PhD

Title(s)Postdoctoral Scholar, Business Service Ctr
SchoolChancellor/EVC/FAS
Address513 Parnassus Ave, HSW
San Francisco CA 94143
Phone--
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CRISPR activation and interference screens decode stimulation responses in primary human T cells. Science. 2022 02 04; 375(6580):eabj4008. Schmidt R, Steinhart Z, Layeghi M, Freimer JW, Bueno R, Nguyen VQ, Blaeschke F, Ye CJ, Marson A. PMID: 35113687.
      View in: PubMed   Mentions:
    2. Evaluation of SARS-CoV-2 serology assays reveals a range of test performance. Nat Biotechnol. 2020 10; 38(10):1174-1183. Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk RP, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. PMID: 32855547; PMCID: PMC7740072.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCellsPHPublic Health
    3. Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer. Nat Commun. 2020 07 24; 11(1):3701. Aubert L, Nandagopal N, Steinhart Z, Lavoie G, Nourreddine S, Berman J, Saba-El-Leil MK, Papadopoli D, Lin S, Hart T, Macleod G, Topisirovic I, Gaboury L, Fahrni CJ, Schramek D, Meloche S, Angers S, Roux PP. PMID: 32709883; PMCID: PMC7381612.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    4. Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation. Proc Natl Acad Sci U S A. 2020 07 14; 117(28):16690-16701. Ma W, Chen M, Kang H, Steinhart Z, Angers S, He X, Kirschner MW. PMID: 32601235; PMCID: PMC7368285.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    5. Test performance evaluation of SARS-CoV-2 serological assays. medRxiv. 2020 May 17. Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk R, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. PMID: 32511497; PMCID: PMC7273265.
      View in: PubMed   Mentions:
    6. IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers. J Cell Biol. 2020 02 03; 219(2). Mis M, O'Brien S, Steinhart Z, Lin S, Hart T, Moffat J, Angers S. PMID: 31881079; PMCID: PMC7041691.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    7. Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice. Elife. 2019 08 27; 8. Tao Y, Mis M, Blazer L, Ustav M, Steinhart Z, Chidiac R, Kubarakos E, O'Brien S, Wang X, Jarvik N, Patel N, Adams J, Moffat J, Angers S, Sidhu SS. PMID: 31452509; PMCID: PMC6711705.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    8. Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells. Cell Rep. 2019 04 16; 27(3):971-986.e9. MacLeod G, Bozek DA, Rajakulendran N, Monteiro V, Ahmadi M, Steinhart Z, Kushida MM, Yu H, Coutinho FJ, Cavalli FMG, Restall I, Hao X, Hart T, Luchman HA, Weiss S, Dirks PB, Angers S. PMID: 30995489.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    9. A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties. MAbs. 2018 Nov-Dec; 10(8):1157-1167. Pavlovic Z, Adams JJ, Blazer LL, Gakhal AK, Jarvik N, Steinhart Z, Robitaille M, Mascall K, Pan J, Angers S, Moffat J, Sidhu SS. PMID: 30183492; PMCID: PMC6284576.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    10. Wnt signaling in development and tissue homeostasis. Development. 2018 06 08; 145(11). Steinhart Z, Angers S. PMID: 29884654.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    11. Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nat Med. 2017 Nov 07; 23(11):1384. Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. PMID: 29117169.
      View in: PubMed   Mentions: 2     Fields:    
    12. Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nat Med. 2017 01; 23(1):60-68. Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. PMID: 27869803.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    13. Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay. J Cell Sci. 2016 10 15; 129(20):3892-3902. Gammons MV, Rutherford TJ, Steinhart Z, Angers S, Bienz M. PMID: 27744318; PMCID: PMC5087658.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    14. Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):9304-9. Cervenka I, Valnohova J, Bernatik O, Harnos J, Radsetoulal M, Sedova K, Hanakova K, Potesil D, Sedlackova M, Salasova A, Steinhart Z, Angers S, Schulte G, Hampl A, Zdrahal Z, Bryja V. PMID: 27486244; PMCID: PMC4995965.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    15. High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. Cell. 2015 Dec 03; 163(6):1515-26. Hart T, Chandrashekhar M, Aregger M, Steinhart Z, Brown KR, MacLeod G, Mis M, Zimmermann M, Fradet-Turcotte A, Sun S, Mero P, Dirks P, Sidhu S, Roth FP, Rissland OS, Durocher D, Angers S, Moffat J. PMID: 26627737.
      View in: PubMed   Mentions: 444     Fields:    Translation:HumansCells
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