Nitesh Khandelwal, PhD

Title(s)Specialist, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th Street, #S412C
San Francisco CA 94158
Phone415-476-3937
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporter efflux protein A. bioRxiv. 2024 Sep 05. Khandelwal NK, Gupta M, Gomez JE, Barkho S, Guan Z, Eng AY, Kawate T, Balasubramani SG, Sali A, Hung DT, Stroud RM. PMID: 39282303; PMCID: PMC11398473.
      View in: PubMed   Mentions:
    2. Cryo-EM reveals a phosphorylated R-domain envelops the NBD1 catalytic domain in an ABC transporter. Life Sci Alliance. 2024 Nov; 7(11). Souza Amado de Carvalho R, Rasel MSI, Khandelwal NK, Tomasiak TM. PMID: 39209537; PMCID: PMC11361370.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Structural Basis of Aquaporin-4 Autoantibody Binding in Neuromyelitis Optica. bioRxiv. 2024 May 14. Gupta M, Khandelwal NK, Nelson A, Hwang P, Pourmal S, Bennett JL, Stroud RM. PMID: 38798537; PMCID: PMC11118524.
      View in: PubMed   Mentions:
    4. Structural Basis for Oxidized Glutathione Recognition by the Yeast Cadmium Factor 1. bioRxiv. 2024 Mar 26. Soong TH, Hotze C, Khandelwal NK, Tomasiak TM. PMID: 38352558; PMCID: PMC10862839.
      View in: PubMed   Mentions:
    5. Cryo-EM structure of the tetra-phosphorylated R-domain in Ycf1 reveals key interactions for transport regulation. bioRxiv. 2024 Mar 24. de Carvalho RSA, Rasel SI, Khandelwal NK, Tomasiak TM. PMID: 38496555; PMCID: PMC10942426.
      View in: PubMed   Mentions:
    6. Structural basis for autoinhibition by the dephosphorylated regulatory domain of Ycf1. Nat Commun. 2024 Mar 16; 15(1):2389. Khandelwal NK, Tomasiak TM. PMID: 38493146; PMCID: PMC10944535.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    7. Inositol Phosphoryl Transferase, Ipt1, Is a Critical Determinant of Azole Resistance and Virulence Phenotypes in Candida glabrata. J Fungi (Basel). 2022 Jun 21; 8(7). Shahi G, Kumar M, Khandelwal NK, Banerjee A, Sarkar P, Kumari S, Esquivel BD, Chauhan N, Chattopadhyay A, White TC, Gaur NA, Singh A, Prasad R. PMID: 35887407; PMCID: PMC9322651.
      View in: PubMed   Mentions: 2  
    8. The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation. Nat Commun. 2022 03 11; 13(1):1278. Khandelwal NK, Millan CR, Zangari SI, Avila S, Williams D, Thaker TM, Tomasiak TM. PMID: 35277487; PMCID: PMC8917219.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    9. Unmasking of CgYor1-Dependent Azole Resistance Mediated by Target of Rapamycin (TOR) and Calcineurin Signaling in Candida glabrata. mBio. 2022 02 22; 13(1):e0354521. Kumari S, Kumar M, Esquivel BD, Wasi M, Pandey AK, Kumar Khandelwal N, Mondal AK, White TC, Prasad R, Gaur NA. PMID: 35038899; PMCID: PMC8764518.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    10. Measuring Gene Expression via mRNA Abundance in Candida auris. Methods Mol Biol. 2022; 2517:155-164. Wasi M, Nair R, Khandelwal NK, Prasad R. PMID: 35674951.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    11. A Conserved Motif in Intracellular Loop 1 Stabilizes the Outward-Facing Conformation of TmrAB. J Mol Biol. 2021 08 06; 433(16):166834. Millan CR, Francis M, Khandelwal NK, Thompson VF, Thaker TM, Tomasiak TM. PMID: 33524413; PMCID: PMC8830738.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    12. A homologous overexpression system to study roles of drug transporters in Candida glabrata. FEMS Yeast Res. 2020 06 01; 20(4). Kumari S, Kumar M, Khandelwal NK, Pandey AK, Bhakt P, Kaur R, Prasad R, Gaur NA. PMID: 32490522; PMCID: PMC7611192.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    13. In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains. Int J Antimicrob Agents. 2020 Mar; 55(3):105865. Orofino F, Truglio GI, Fiorucci D, D'Agostino I, Borgini M, Poggialini F, Zamperini C, Dreassi E, Maccari L, Torelli R, Martini C, Bernabei M, Meis JF, Khandelwal NK, Prasad R, Sanguinetti M, Bugli F, Botta M. PMID: 31866465.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    14. ABC Transporter Genes Show Upregulated Expression in Drug-Resistant Clinical Isolates of Candida auris: A Genome-Wide Characterization of ATP-Binding Cassette (ABC) Transporter Genes. Front Microbiol. 2019; 10:1445. Wasi M, Khandelwal NK, Moorhouse AJ, Nair R, Vishwakarma P, Bravo Ruiz G, Ross ZK, Lorenz A, Rudramurthy SM, Chakrabarti A, Lynn AM, Mondal AK, Gow NAR, Prasad R. PMID: 31379756; PMCID: PMC6647914.
      View in: PubMed   Mentions: 33  
    15. Vacuolar Sequestration of Azoles, a Novel Strategy of Azole Antifungal Resistance Conserved across Pathogenic and Nonpathogenic Yeast. Antimicrob Agents Chemother. 2019 03; 63(3). Khandelwal NK, Wasi M, Nair R, Gupta M, Kumar M, Mondal AK, Gaur NA, Prasad R. PMID: 30642932; PMCID: PMC6395933.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    16. Lipidomics Approaches: Applied to the Study of Pathogenesis in Candida Species. Prog Mol Subcell Biol. 2019; 58:195-215. Singh A, Khandelwal NK, Prasad R. PMID: 30911894.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    17. All about CDR transporters: Past, present, and future. Yeast. 2019 04; 36(4):223-233. Prasad R, Balzi E, Banerjee A, Khandelwal NK. PMID: 30192990.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    18. ABC transportome inventory of human pathogenic yeast Candida glabrata: Phylogenetic and expression analysis. PLoS One. 2018; 13(8):e0202993. Kumari S, Kumar M, Khandelwal NK, Kumari P, Varma M, Vishwakarma P, Shahi G, Sharma S, Lynn AM, Prasad R, Gaur NA. PMID: 30153284; PMCID: PMC6112666.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    19. Inventory of ABC proteins and their putative role in salt and drug tolerance in Debaryomyces hansenii. Gene. 2018 Nov 15; 676:227-242. Wasi M, Khandelwal NK, Vishwakarma P, Lynn AM, Mondal AK, Prasad R. PMID: 30025928.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    20. Identification of genome-wide binding sites of heat shock factor 1, Hsf1, under basal conditions in the human pathogenic yeast, Candida albicans. AMB Express. 2018 Jul 16; 8(1):116. Nair R, Khandelwal NK, Shariq M, Redhu AK, Gaur NA, Shaikh S, Prasad R. PMID: 30014253; PMCID: PMC6047955.
      View in: PubMed   Mentions: 2  
    21. Phosphatidylserine decarboxylase governs plasma membrane fluidity and impacts drug susceptibilities of Candida albicans cells. Biochim Biophys Acta Biomembr. 2018 11; 1860(11):2308-2319. Khandelwal NK, Sarkar P, Gaur NA, Chattopadhyay A, Prasad R. PMID: 29856993.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    22. Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling. J Biol Chem. 2018 01 12; 293(2):412-432. Khandelwal NK, Chauhan N, Sarkar P, Esquivel BD, Coccetti P, Singh A, Coste AT, Gupta M, Sanglard D, White TC, Chauvel M, d'Enfert C, Chattopadhyay A, Gaur NA, Mondal AK, Prasad R. PMID: 29158264; PMCID: PMC5767851.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    23. pHluorin enables insights into the transport mechanism of antiporter Mdr1: R215 is critical for drug/H+ antiport. Biochem J. 2016 10 01; 473(19):3127-45. Redhu AK, Khandelwal NK, Banerjee A, Moreno A, Falson P, Prasad R. PMID: 27433020.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    24. Yeast ABC transporters in lipid trafficking. Fungal Genet Biol. 2016 08; 93:25-34. Prasad R, Khandelwal NK, Banerjee A. PMID: 27259587.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    25. Pleiotropic effects of the vacuolar ABC transporter MLT1 of Candida albicans on cell function and virulence. Biochem J. 2016 06 01; 473(11):1537-52. Khandelwal NK, Kaemmer P, Förster TM, Singh A, Coste AT, Andes DR, Hube B, Sanglard D, Chauhan N, Kaur R, d'Enfert C, Mondal AK, Prasad R. PMID: 27026051; PMCID: PMC4888455.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    26. A New Endogenous Overexpression System of Multidrug Transporters of Candida albicans Suitable for Structural and Functional Studies. Front Microbiol. 2016; 7:261. Banerjee A, Khandelwal NK, Sanglard D, Prasad R. PMID: 26973635; PMCID: PMC4776216.
      View in: PubMed   Mentions: 1  
    27. The ABCs of Candida albicans Multidrug Transporter Cdr1. Eukaryot Cell. 2015 Dec; 14(12):1154-64. Prasad R, Banerjee A, Khandelwal NK, Dhamgaye S. PMID: 26407965; PMCID: PMC4664872.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    28. An assessment of growth media enrichment on lipid metabolome and the concurrent phenotypic properties of Candida albicans. PLoS One. 2014; 9(11):e113664. Mahto KK, Singh A, Khandelwal NK, Bhardwaj N, Jha J, Prasad R. PMID: 25423360; PMCID: PMC4244132.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    29. Molecular mechanisms of action of herbal antifungal alkaloid berberine, in Candida albicans. PLoS One. 2014; 9(8):e104554. Dhamgaye S, Devaux F, Vandeputte P, Khandelwal NK, Sanglard D, Mukhopadhyay G, Prasad R. PMID: 25105295; PMCID: PMC4126717.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
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