Rahul Kumar, PhD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address2540 23rd Street, #4315
San Francisco CA 94110
PronounsHe/Him/His
ORCID ORCID Icon0000-0002-2709-5981 Additional info
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    Collapse Biography 
    Collapse education and training
    Lalit Narayan Mithila University, Darbhanga, Bihar, IndiaBS2002Zoology (H)
    Bundelkhand University, Jhansi, UP, IndiaMS2005Biotechnology
    CSIR-Institute of Genomics and Integrative Biology and Hamdard University, Delhi, IndiaPhD2012Biotechnology
    University of Colorado, Aurora, Colorado, USApost-doc2019Pulmonary Sciences
    Collapse awards and honors
    American Heart Association, USA2017Postdoctoral Fellowship Award
    5th international Leh Symposium, India2018Young Investigator Award
    American Society of Hypertension, New York, USA2010Boehringer Ingelheim Young Investigator Travel Award
    UCSF-Pulmonary Retreat2022Best Poster Award
    University of Colorado, Denver 2015Certificate of Appreciation for Promoting diversity
    American Journal of Physiology-Lung Cellular and Molecular Physiology2015Distinction in scholarship
    Pulmonary Circulation2014Editorial Highlights: review article “Schistosomiasis and the pulmonary vasculature
    United Therapeutics, USA2022Jenesis Innovator Research Award
    American Thoracic Society2024Early Career Investigator Award

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Breathing New Life into PAH Treatment: Targeting Serotonin Synthesis with an Inhalation Approach. Am J Respir Cell Mol Biol. 2025 Feb 07. Lee MH, Kumar R. PMID: 39918913.
      View in: PubMed   Mentions:    Fields:    
    2. Monocytes and interstitial macrophages contribute to hypoxic pulmonary hypertension. J Clin Invest. 2025 Jan 30; 135(6). Kumar R, Nolan K, Kassa B, Chanana N, Palmo T, Sharma K, Singh K, Mickael C, Fonseca Balladares D, Nilsson J, Prabhakar A, Mishra A, Lee MH, Sanders L, Kumar S, Molofsky AB, Stenmark KR, Sheppard D, Tuder RM, Gupta MD, Thinlas T, Pasha Q, Graham BB. PMID: 39883518; PMCID: PMC11910231.
      View in: PubMed   Mentions:    Fields:    
    3. Reply to the letter to the editor entitled "Bridging the species divide: The limits of rat models in capturing human PVOD mechanisms" by Perros F. et al. Pulm Circ. 2024 Oct; 14(4):e70015. Prabhakar A, Kumar R, Wadhwa M, Tuder RM, Morrell NW, Graham BB, Lagna G, Hata A. PMID: 39544196; PMCID: PMC11560859.
      View in: PubMed   Mentions:
    4. Mechanisms underlying age-associated exacerbation of pulmonary veno-occlusive disease. JCI Insight. 2024 Sep 05; 9(19). Prabhakar A, Wadhwa M, Kumar R, Ghatpande P, Gandjeva A, Tuder RM, Graham BB, Lagna G, Hata A. PMID: 39269983; PMCID: PMC11466196.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. Classical dendritic cells contribute to hypoxia-induced pulmonary hypertension. FASEB J. 2024 Aug 31; 38(16):e70015. Mickael C, Sanders LA, Lee MH, Kumar R, Fonseca-Balladares D, Gandjeva A, Cautivo-Reyes K, Kassa B, Kumar S, Irwin D, Swindle D, Phang T, Stearman RS, Molofsky AB, McKee AS, Stenmark KR, Graham BB, Tuder RM. PMID: 39212294; PMCID: PMC11462638.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Intrapulmonary T Cells Are Sufficient for Schistosoma-Induced Pulmonary Hypertension. Int J Mol Sci. 2024 Aug 24; 25(17). Fonseca Balladares DC, Kassa B, Mickael C, Kumar R, Nolan K, Menezes TCF, Lee MH, Lau-Xiao AM, Molofsky AB, Wells E, Graham BB. PMID: 39273153; PMCID: PMC11395458.
      View in: PubMed   Mentions:    Fields:    
    7. Reversal of pulmonary veno-occlusive disease phenotypes by inhibition of the integrated stress response. Nat Cardiovasc Res. 2024 Jul; 3(7):799-818. Prabhakar A, Kumar R, Wadhwa M, Ghatpande P, Zhang J, Zhao Z, Lizama CO, Kharbikar BN, Gräf S, Treacy CM, Morrell NW, Graham BB, Lagna G, Hata A. PMID: 39196173; PMCID: PMC11409862.
      View in: PubMed   Mentions: 3  Translation:HumansAnimalsCells
    8. Interstitial macrophage phenotypes in Schistosoma-induced pulmonary hypertension. Front Immunol. 2024; 15:1372957. Kumar R, Kumar S, Mickael C, Fonseca Balladares D, Nolan K, Lee MH, Sanders L, Nilsson J, Molofsky AB, Tuder RM, Stenmark KR, Graham BB. PMID: 38779688; PMCID: PMC11109442.
      View in: PubMed   Mentions:    Fields:    
    9. Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension. Front Immunol. 2024; 15:1372959. Kumar S, Mickael C, Kumar R, Prasad RR, Campbell NV, Zhang H, Li M, McKeon BA, Allen TE, Graham BB, Yu YA, Stenmark KR. PMID: 38690277; PMCID: PMC11059952.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    10. Experimental Schistosoma haematobium pulmonary hypertension. Pulm Circ. 2024 Jan; 14(1):e12336. Kassa B, Fonseca-Balladares DC, Kumar R, Lee MH, Mickael C, Sanders L, Nolan K, Graham BB. PMID: 38312832; PMCID: PMC10835079.
      View in: PubMed   Mentions: 1  
    11. Dexamethasone prophylaxis protects from acute high-altitude illness by modifying the peripheral blood mononuclear cell inflammatory transcriptome. Biosci Rep. 2023 11 30; 43(11). Kumar R, Chanana N, Sharma K, Palmo T, Lee MH, Mishra A, Nolan K, Fonseca Balladares DC, Mickael C, Gupta MD, Thinlas T, Pasha Q, Graham BB. PMID: 37975243; PMCID: PMC10695741.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    12. Is pulmonary arterial hypertension associated with schistosomiasis distinct from pulmonary arterial hypertension associated with portal hypertension? JHLT Open. 2023 Oct; 1. Graham BB, Hilton JF, Lee MH, Kumar R, Balladares DF, Rahaghi FN, Estépar RSJ, Mickael C, Lima RLB, Loureiro CMC, Lucena J, Oliveira RKF, Corrêa RA. PMID: 38050478; PMCID: PMC10695267.
      View in: PubMed   Mentions: 2  
    13. Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension. Clin Sci (Lond). 2023 04 26; 137(8):617-631. Kumar R, Lee MH, Kassa B, Fonseca Balladares DC, Mickael C, Sanders L, Andruska A, Kumar M, Spiekerkoetter E, Bandeira A, Stenmark KR, Tuder RM, Graham BB. PMID: 37014925; PMCID: PMC10133871.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    14. Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: Multilayered cross-talks in the setting of coinfections and comorbidities. PLoS Pathog. 2023 01; 19(1):e1011063. Kumar R, Aktay-Cetin Ö, Craddock V, Morales-Cano D, Kosanovic D, Cogolludo A, Perez-Vizcaino F, Avdeev S, Kumar A, Ram AK, Agarwal S, Chakraborty A, Savai R, de Jesus Perez V, Graham BB, Butrous G, Dhillon NK. PMID: 36634048; PMCID: PMC9836319.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    15. HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape. Cells. 2022 08 04; 11(15). Medrano-Garcia S, Morales-Cano D, Barreira B, Vera-Zambrano A, Kumar R, Kosanovic D, Schermuly RT, Graham BB, Perez-Vizcaino F, Mathie A, Savai R, Pullamseti S, Butrous G, Fernández-Malavé E, Cogolludo A. PMID: 35954255; PMCID: PMC9368261.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    16. The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension. Pulm Circ. 2022 Jul; 12(3):e12105. Gu S, Mickael C, Kumar R, Lee MH, Sanders L, Kassa B, Harral J, Williams J, Hansen KC, Stenmark KR, Tuder RM, Graham BB. PMID: 35874852; PMCID: PMC9297026.
      View in: PubMed   Mentions: 3  
    17. Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L355-L371. Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, Graham BB, Tuder RM. PMID: 35763400; PMCID: PMC9448289.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    18. Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia. Am J Physiol Lung Cell Mol Physiol. 2022 07 01; 323(1):L58-L68. Campbell NV, Mickael C, Kumar S, Zhang H, Campbell IL, Gillen AE, Trentin CO, Diener K, Gao B, Kheyfets VO, Gu S, Kumar R, Phang T, Brown RD, Graham BB, Stenmark KR. PMID: 35608266; PMCID: PMC9273277.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    19. Sexual Dimorphism of Dexamethasone as a Prophylactic Treatment in Pathologies Associated With Acute Hypobaric Hypoxia Exposure. Front Pharmacol. 2022; 13:873867. Chanana N, Palmo T, Sharma K, Kumar R, Shah B, Mahajan S, Palleda GM, Gupta MD, Kukreti R, Faruq M, Thinlas T, Graham BB, Pasha Q. PMID: 35668947; PMCID: PMC9163683.
      View in: PubMed   Mentions: 1  
    20. Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension. J Clin Invest. 2022 May 16; 132(10). Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. PMID: 35575096; PMCID: PMC9106337.
      View in: PubMed   Mentions: 3     Fields:    
    21. Rationale and design of a screening study to detect schistosomiasis-associated pulmonary hypertension in Ethiopia and Zambia. Pulm Circ. 2022 Apr; 12(2):e12072. Sinkala E, Ahmed HY, Sibomana JP, Lee MH, Kassa B, Kumar R, Mazimba S, Binegdie AB, Mpisa S, Wamundila K, Graham BB, Hilton JF. PMID: 35514775; PMCID: PMC9063961.
      View in: PubMed   Mentions: 1  
    22. Experimental Schistosoma japonicum-induced pulmonary hypertension. PLoS Negl Trop Dis. 2022 04; 16(4):e0010343. Kassa B, Lee MH, Kumar R, Mickael C, Sanders L, Tuder RM, Mentink-Kane M, Graham BB. PMID: 35417453; PMCID: PMC9037943.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    23. Endothelial cell PHD2-HIF1α-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2021 10 01; 321(4):L675-L685. Kassa B, Kumar R, Mickael C, Sanders L, Vohwinkel C, Lee MH, Gu S, Poth JM, Stenmark KR, Zhao YY, Tuder RM, Graham BB. PMID: 34346780; PMCID: PMC8560395.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    24. Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension. Cell Mol Immunol. 2021 02; 18(2):374-384. Florentin J, Zhao J, Tai YY, Vasamsetti SB, O'Neil SP, Kumar R, Arunkumar A, Watson A, Sembrat J, Bullock GC, Sanders L, Kassa B, Rojas M, Graham BB, Chan SY, Dutta P. PMID: 33420357; PMCID: PMC8027442.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    25. Schistosomiasis Pulmonary Arterial Hypertension. Front Immunol. 2020; 11:608883. Sibomana JP, Campeche A, Carvalho-Filho RJ, Correa RA, Duani H, Pacheco Guimaraes V, Hilton JF, Kassa B, Kumar R, Lee MH, Loureiro CMC, Mazimba S, Mickael C, Oliveira RKF, Ota-Arakaki JS, Rezende CF, Silva LCS, Sinkala E, Ahmed HY, Graham BB. PMID: 33362796; PMCID: PMC7758287.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    26. Pathophysiology and potential future therapeutic targets using preclinical models of COVID-19. ERJ Open Res. 2020 Oct; 6(4). Kumar R, Lee MH, Mickael C, Kassa B, Pasha Q, Tuder R, Graham B. PMID: 33313306; PMCID: PMC7720688.
      View in: PubMed   Mentions: 6  
    27. Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension. Cardiovasc Res. 2020 10 01; 116(12):2021-2030. Kumar R, Mickael C, Kassa B, Sanders L, Hernandez-Saavedra D, Koyanagi DE, Kumar S, Pugliese SC, Thomas S, McClendon J, Maloney JP, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. PMID: 31710666; PMCID: PMC7519884.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    28. Sex-derived attributes contributing to SARS-CoV-2 mortality. Am J Physiol Endocrinol Metab. 2020 09 01; 319(3):E562-E567. Chanana N, Palmo T, Sharma K, Kumar R, Graham BB, Pasha Q. PMID: 32726128; PMCID: PMC7473885.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCellsPHPublic Health
    29. Susceptibility to high-altitude pulmonary edema is associated with circulating miRNA levels under hypobaric hypoxia conditions. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L360-L368. Alam P, Agarwal G, Kumar R, Mishra A, Saini N, Mohammad G, Pasha MAQ. PMID: 32692577.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    30. Publisher Correction: Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. Sci Rep. 2020 Mar 04; 10(1):4349. Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB. PMID: 32132567; PMCID: PMC7055208.
      View in: PubMed   Mentions: 4     Fields:    
    31. Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. Sci Rep. 2020 01 15; 10(1):413. Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB. PMID: 31942023; PMCID: PMC6962446.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    32. Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma-Pulmonary Hypertension. J Am Heart Assoc. 2019 08 06; 8(15):e013111. Kumar R, Mickael C, Kassa B, Sanders L, Koyanagi D, Hernandez-Saavedra D, Freeman S, Morales-Cano D, Cogolludo A, McKee AS, Fontenot AP, Butrous G, Tuder RM, Graham BB. PMID: 31339057; PMCID: PMC6761627.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. IL-6Ra in Smooth Muscle Cells Protects against Schistosoma- and Hypoxia-induced Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2019 07; 61(1):123-126. Mickael C, Kumar R, Hernandez-Saavedra D, Kassa B, Sanders L, Koyanagi D, Gu S, Lee MH, Tuder RM, Graham BB. PMID: 31259624; PMCID: PMC6604223.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    34. BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension. Circulation. 2019 05 07; 139(19):2238-2255. Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY. PMID: 30759996; PMCID: PMC6519484.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    35. Common genetic variants in pulmonary arterial hypertension. Lancet Respir Med. 2019 03; 7(3):190-191. Gu S, Kumar R, Lee MH, Mickael C, Graham BB. PMID: 30527955; PMCID: PMC6768546.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    36. Paclitaxel blocks Th2-mediated TGF-β activation in Schistosoma mansoni-induced pulmonary hypertension. Pulm Circ. 2019 Jan-Mar; 9(1):2045894018820813. Kassa B, Mickael C, Kumar R, Sanders L, Koyanagi D, Hernandez-Saavedra D, Tuder RM, Graham BB. PMID: 30511588; PMCID: PMC6304706.
      View in: PubMed   Mentions: 4  
    37. Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2018 10; 59(4):479-489. Graham BB, Kumar R, Mickael C, Kassa B, Koyanagi D, Sanders L, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Harral J, Loomis Z, Irwin D, Nemkov T, D'Alessandro A, Stenmark KR, Tuder RM. PMID: 29851508; PMCID: PMC6178158.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    38. IL-33-HIF1α Axis in Hypoxic Pulmonary Hypertension. EBioMedicine. 2018 07; 33:8-9. Kumar R, Graham B. PMID: 30049389; PMCID: PMC6085541.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    39. NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension. Sci Transl Med. 2018 06 13; 10(445). Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA. PMID: 29899023; PMCID: PMC6223025.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    40. How does inflammation contribute to pulmonary hypertension? Eur Respir J. 2018 01; 51(1). Kumar R, Graham B. PMID: 29371392; PMCID: PMC5973838.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    41. TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension. Nat Commun. 2017 05 30; 8:15494. Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, Morgan LE, Evans CM, Hernandez-Saavedra D, Bandeira A, Maloney JP, Bull TM, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. PMID: 28555642; PMCID: PMC5459967.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    42. Impact of interactions between risk alleles on clinical endpoints in hypertension. Heart Asia. 2016; 8(1):83-9. Kohli S, Kumar R, Gupta M, Tyagi S, Pasha MA. PMID: 27326240; PMCID: PMC4898629.
      View in: PubMed   Mentions: 4  
    43. Unveiling the interactions among BMPR-2, ALK-1 and 5-HTT genes in the pathophysiology of HAPE. Gene. 2016 Aug 22; 588(2):163-72. Ali Z, Waseem M, Kumar R, Pandey P, Mohammad G, Qadar Pasha MA. PMID: 27196063.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    44. Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. Cell Rep. 2015 Nov 03; 13(5):1016-32. Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. PMID: 26565914; PMCID: PMC4644508.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    45. The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension. Am J Respir Crit Care Med. 2015 Oct 15; 192(8):998-1008. Kumar R, Mickael C, Chabon J, Gebreab L, Rutebemberwa A, Garcia AR, Koyanagi DE, Sanders L, Gandjeva A, Kearns MT, Barthel L, Janssen WJ, Mauad T, Bandeira A, Schmidt E, Tuder RM, Graham BB. PMID: 26192556; PMCID: PMC4642207.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    46. Severe pulmonary hypertension is associated with altered right ventricle metabolic substrate uptake. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 01; 309(5):L435-40. Graham BB, Kumar R, Mickael C, Sanders L, Gebreab L, Huber KM, Perez M, Smith-Jones P, Serkova NJ, Tuder RM. PMID: 26115672; PMCID: PMC4556932.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    47. Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension. EMBO Mol Med. 2015 Jun; 7(6):695-713. White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY. PMID: 25825391; PMCID: PMC4459813.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    48. CYBA (p22phox) variants associate with blood pressure and oxidative stress markers in hypertension: a replication study in populations of diverse altitudes. Hypertens Res. 2015 Jul; 38(7):498-506. Kumar R, Kohli S, Ali Z, Duhan K, Ram R, Gupta M, Tyagi S, Mohammad G, Pasha MQ. PMID: 25787042.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    49. Schistosomiasis and the pulmonary vasculature (2013 Grover Conference series). Pulm Circ. 2014 Sep; 4(3):353-62. Graham BB, Kumar R. PMID: 25621148; PMCID: PMC4278594.
      View in: PubMed   Mentions: 14  
    50. Interactions between the genes of vasodilatation pathways influence blood pressure and nitric oxide level in hypertension. Am J Hypertens. 2015 Feb; 28(2):239-47. Kumar R, Kohli S, Mishra A, Garg R, Alam P, Stobdan T, Nejatizadeh A, Gupta M, Tyagi S, Pasha MA. PMID: 25159081.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    51. Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension. J Clin Invest. 2014 08; 124(8):3514-28. Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. PMID: 24960162; PMCID: PMC4109523.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansAnimalsCells
    52. β-T594M epithelial sodium channel gene polymorphism and essential hypertension in individuals of Indo-Aryan ancestry in Northern India. Indian Heart J. 2014 Jul-Aug; 66(4):397-400. Gupta MD, Girish MP, Sikdar S, Ahuja R, Shah D, Kumar R, Rain M, Nejatizadeh A, Tyagi S, Pasha Q. PMID: 25173196; PMCID: PMC4150039.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    53. Role of vascular endothelial growth factor signaling in Schistosoma-induced experimental pulmonary hypertension. Pulm Circ. 2014 Jun; 4(2):289-99. Chabon JJ, Gebreab L, Kumar R, Debella E, Tanaka T, Koyanagi D, Rodriguez Garcia A, Sanders L, Perez M, Tuder RM, Graham BB. PMID: 25006448; PMCID: PMC4070790.
      View in: PubMed   Mentions: 4  
    54. Association between the Glu298Asp and 4b/4a polymorphisms of endothelial nitric oxide synthase and coronary slow flow in the North Indian population. Coron Artery Dis. 2014 May; 25(3):192-7. Gupta MD, Akkarappatty C, Girish MP, Kumar R, Rain M, Tyagi S, Qadar Pasha MA. PMID: 24525787.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    55. Protective role of IL-6 in vascular remodeling in Schistosoma pulmonary hypertension. Am J Respir Cell Mol Biol. 2013 Dec; 49(6):951-9. Graham BB, Chabon J, Kumar R, Kolosionek E, Gebreab L, Debella E, Edwards M, Diener K, Shade T, Bifeng G, Bandeira A, Butrous G, Jones K, Geraci M, Tuder RM. PMID: 23815102; PMCID: PMC3931110.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    56. Pathology of pulmonary hypertension. Clin Chest Med. 2013 Dec; 34(4):639-50. Tuder RM, Stacher E, Robinson J, Kumar R, Graham BB. PMID: 24267295.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimals
    57. Interactions between the FTO and GNB3 genes contribute to varied clinical phenotypes in hypertension. PLoS One. 2013; 8(5):e63934. Kumar R, Kohli S, Alam P, Barkotoky R, Gupta M, Tyagi S, Jain SK, Pasha MA. PMID: 23691120; PMCID: PMC3653800.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    58. Interactions among vascular-tone modulators contribute to high altitude pulmonary edema and augmented vasoreactivity in highlanders. PLoS One. 2012; 7(9):e44049. Ali Z, Mishra A, Kumar R, Alam P, Pandey P, Ram R, Thinlas T, Mohammad G, Pasha MA. PMID: 22984459; PMCID: PMC3439466.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    59. CYBA and GSTP1 variants associate with oxidative stress under hypobaric hypoxia as observed in high-altitude pulmonary oedema. Clin Sci (Lond). 2012 Mar; 122(6):299-309. Mishra A, Ali Z, Vibhuti A, Kumar R, Alam P, Ram R, Thinlas T, Mohammad G, Pasha MA. PMID: 21973220.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    60. The epistasis between vascular homeostasis genes is apparent in essential hypertension. Atherosclerosis. 2012 Feb; 220(2):418-24. Kumar R, Nejatizadeh A, Gupta M, Markan A, Tyagi S, Jain SK, Pasha MA. PMID: 22134143.
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    61. Association of GNB3 C825T polymorphism with plasma electrolyte balance and susceptibility to hypertension. Genet Mol Biol. 2011 Oct; 34(4):553-6. Nejatizadeh A, Kumar R, Stobdan T, Pasha MQ. PMID: 22215956; PMCID: PMC3229107.
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    62. CYP11B2 gene haplotypes independently and in concurrence with aldosterone and aldosterone to renin ratio increase the risk of hypertension. Clin Biochem. 2010 Jan; 43(1-2):136-41. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Gupta M, Tyagi S, Jain SK, Pasha MA. PMID: 19786005.
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    63. Multi-locus interactions of vascular homeostasis genes in essential hypertension: a gender-based study. Clin Chim Acta. 2009 Jul; 405(1-2):87-93. Kumar R, Nejatizadeh A, Arif E, Akhtar S, Gupta M, Tyagi S, Goyal AK, Jain SK, Qadar Pasha MA. PMID: 19379721.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    64. Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension. J Hypertens. 2008 Jun; 26(6):1094-101. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Gupta M, Javed S, Pasha MQ. PMID: 18475146.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    65. Endothelial nitric oxide synthase gene haplotypes and circulating nitric oxide levels significantly associate with risk of essential hypertension. Free Radic Biol Med. 2008 Jun 01; 44(11):1912-8. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Sikdar S, Gupta M, Javed S, Pasha MA. PMID: 18325347.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
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