-
Microenvironmental control of hematopoietic stem cell fate via CXCL8 and protein kinase C. Cell Rep. 2023 May 18; 42(5):112528.
Binder V, Li W, Faisal M, Oyman K, Calkins DL, Shaffer J, Teets EM, Sher S, Magnotte A, Belardo A, Deruelle W, Gregory TC, Orwick S, Hagedorn EJ, Perlin JR, Avagyan S, Lichtig A, Barrett F, Ammerman M, Yang S, Zhou Y, Carson WE, Shive HR, Blachly JS, Lapalombella R, Zon LI, Blaser BW. PMID: 37209097.
View in:
PubMed Mentions: Fields:
-
Clonal hematopoiesis and inflammation - the perpetual cycle. Trends Cell Biol. 2022 Dec 31.
Avagyan S, Zon LI. PMID: 36593155.
View in:
PubMed Mentions:
2 Fields:
-
Lessons From Pediatric MDS: Approaches to Germline Predisposition to Hematologic Malignancies. Front Oncol. 2022; 12:813149.
Avagyan S, Shimamura A. PMID: 35356204; PMCID: PMC8959480.
View in:
PubMed Mentions:
2
-
Resistance to inflammation underlies enhanced fitness in clonal hematopoiesis. Science. 2021 Nov 05; 374(6568):768-772.
Avagyan S, Henninger JE, Mannherz WP, Mistry M, Yoon J, Yang S, Weber MC, Moore JL, Zon LI. PMID: 34735227.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
To T or not to B: germline RUNX1 mutation preferences in pediatric ALL predisposition. J Clin Invest. 2021 09 01; 131(17).
Avagyan S, Brown AL. PMID: 34623329; PMCID: PMC8409576.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
B-cell acute lymphoblastic leukemia in patients with germline RUNX1 mutations. Blood Adv. 2021 08 24; 5(16):3199-3202.
Six KA, Gerdemann U, Brown AL, Place AE, Cantor AB, Kutny MA, Avagyan S. PMID: 34424323; PMCID: PMC8405188.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Single-cell ATAC-seq reveals GATA2-dependent priming defect in myeloid and a maturation bottleneck in lymphoid lineages. Blood Adv. 2021 07 13; 5(13):2673-2686.
Avagyan S, Weber MC, Ma S, Prasad M, Mannherz WP, Yang S, Buenrostro JD, Zon LI. PMID: 34170284; PMCID: PMC8221101.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Comparison of Outcomes of Myeloablative Allogeneic Stem Cell Transplantation for Pediatric Patients with Bone Marrow Failure, Myelodysplastic Syndrome and Acute Myeloid Leukemia with and without Germline GATA2 Mutations. Biol Blood Marrow Transplant. 2020 06; 26(6):1124-1130.
Hofmann I, Avagyan S, Stetson A, Guo D, Al-Sayegh H, London WB, Lehmann L. PMID: 32088370; PMCID: PMC7276093.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors. Zebrafish. 2017 08; 14(4):379-382.
Fazio M, Avagyan S, van Rooijen E, Mannherz W, Kaufman CK, Lobbardi R, Langenau DM, Zon LI. PMID: 28557653; PMCID: PMC5549793.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Understanding the regulation of vertebrate hematopoiesis and blood disorders - big lessons from a small fish. FEBS Lett. 2016 Nov; 590(22):4016-4033.
Robertson AL, Avagyan S, Gansner JM, Zon LI. PMID: 27616157; PMCID: PMC5483340.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Mol Cell. 2016 Apr 07; 62(1):34-46.
Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young RA, Zon LI. PMID: 27058786; PMCID: PMC4836061.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
-
Fish to Learn: Insights into Blood Development and Blood Disorders from Zebrafish Hematopoiesis. Hum Gene Ther. 2016 Apr; 27(4):287-94.
Avagyan S, Zon LI. PMID: 27018965; PMCID: PMC4841069.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
-
Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency. Blood. 2014 Sep 04; 124(10):1622-5.
Avagyan S, Churchill M, Yamamoto K, Crowe JL, Li C, Lee BJ, Zheng T, Mukherjee S, Zha S. PMID: 25075129; PMCID: PMC4155271.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Propranolol as a first-line treatment for diffuse infantile hepatic hemangioendothelioma. J Pediatr Gastroenterol Nutr. 2013 Mar; 56(3):e17-20.
Avagyan S, Klein M, Kerkar N, Demattia A, Blei F, Lee S, Rosenberg HK, Arnon R. PMID: 22331019.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis. Blood. 2011 Dec 01; 118(23):6078-86.
Avagyan S, Aguilo F, Kamezaki K, Snoeck HW. PMID: 21967974; PMCID: PMC3234666.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood. 2011 May 12; 117(19):5057-66.
Aguilo F, Avagyan S, Labar A, Sevilla A, Lee DF, Kumar P, Lemischka IR, Zhou BY, Snoeck HW. PMID: 21343612; PMCID: PMC3109532.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
-
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science. 2010 Jun 25; 328(5986):1689-93.
Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR. PMID: 20488992; PMCID: PMC3032591.
View in:
PubMed Mentions:
349 Fields:
Translation:
AnimalsCells
-
A quantitative trait locus on chr.4 regulates thymic involution. J Gerontol A Biol Sci Med Sci. 2010 Jun; 65(6):620-5.
Kumar R, Avagyan S, Snoeck HW. PMID: 20371546; PMCID: PMC2904592.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Identification and in vivo analysis of murine hematopoietic stem cells. Methods Enzymol. 2010; 476:429-47.
Avagyan S, Amrani YM, Snoeck HW. PMID: 20691879.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
A quantitative trait locus on chromosome 4 affects cycling of hematopoietic stem and progenitor cells through regulation of TGF-beta 2 responsiveness. J Immunol. 2008 Nov 01; 181(9):5904-11.
Avagyan S, Glouchkova L, Choi J, Snoeck HW. PMID: 18941179; PMCID: PMC2630176.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Test of Cairns-Smith's 'crystals-as-genes' hypothesis. Faraday Discuss. 2007; 136:231-45; discussion 309-28.
Bullard T, Freudenthal J, Avagyan S, Kahr B. PMID: 17955812.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
-
Immunokinetics of autoreactive CD4 T cells in blood: a reporter for the "hit-and-run" autoimmune attack on pancreas and diabetes progression. J Autoimmun. 2004 Sep; 23(2):151-60.
George SK, Preda I, Avagyan S, McEvoy RC, Rapaport R, Brumeanu TD, Casares S. PMID: 15324933.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Selection footprint in the FimH adhesin shows pathoadaptive niche differentiation in Escherichia coli. Mol Biol Evol. 2004 Jul; 21(7):1373-83.
Sokurenko EV, Feldgarden M, Trintchina E, Weissman SJ, Avagyan S, Chattopadhyay S, Johnson JR, Dykhuizen DE. PMID: 15044596.
View in:
PubMed Mentions:
52 Fields:
Translation:
Cells