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Lena Winestone, MD

Title(s)Assistant Professor, Pediatrics
SchoolSchool of Medicine
ORCID ORCID Icon0000-0001-9982-1594 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of PennsylvaniaBA2004Biochemistry
    Stanford University School of MedicineMD2009Medicine
    Lucile Packard Children's HospitalResidency2012Pediatrics
    Children's Hospital of PhiladelphiaFellowship2016Pediatric Hematology/Oncology
    Perelman School of Medicine, University of PennsylvaniaMSHP2016Health Policy Research
    Collapse Awards and Honors
    American Society of Hematology2016Clinical Research Training Institute
    Bear Necessities Pediatric Cancer Foundation2016  - 2017Fellow Award
    Abramson Cancer Center2016  - 2018Paul Calabresi Career Development Award for Clinical Oncology (K12)
    Alex's Lemonade Stand Foundation 2016  - 2019Young Investigator Award

    Collapse Overview 
    Collapse Overview
    My research explores racial, ethnic, and socioeconomic disparities in access to care and outcome of leukemia and lymphoma treatment. I study access to care across the continuum of pediatric cancer from diagnosis and clinical trial enrollment through treatment and relapse to salvage therapies. My research has shown that African American children with acute lymphoblastic leukemia, acute myeloid leukemia, and mature B cell lymphoma are two times more likely to present with organ failure at the time of a new cancer diagnosis. My ongoing work investigates access to highly specialized and complex therapies such as stem cell transplant, chimeric antigen receptor T cells, and MIBG therapy.

    Collapse Research 
    Collapse Research Activities and Funding
    In Depth Interviews regarding the Path to a Leukemia Diagnosis
    Alex's Lemonade Stand Foundation, Bear Necessities Pediatric Cancer Foundation Dec 1, 2018

    Collapse ORNG Applications 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Friend BD, Bailey-Olson M, Melton A, Shimano KA, Kharbanda S, Higham C, Winestone LE, Huang J, Stieglitz E, Dvorak CC. The impact of total body irradiation-based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2019 Nov 14; e28079. PMID: 31724815.
      View in: PubMed
    2. Winestone L, Cabana MD. 50 Years Ago in TheJournal ofPediatrics: Fifty-Two Forms of Childhood Cancer, United States Mortality Experience, 1960-1966. J Pediatr. 2019 Oct; 213:148. PMID: 31561775.
      View in: PubMed
    3. Winestone LE, Aplenc R. Disparities in Survival and Health Outcomes in Childhood Leukemia. Curr Hematol Malig Rep. 2019 Jun; 14(3):179-186. PMID: 31073772.
      View in: PubMed
    4. Winestone LE, Getz KD, Rao P, Li Y, Hall M, Huang YV, Seif AE, Fisher BT, Aplenc R. Disparities in pediatric acute myeloid leukemia (AML) clinical trial enrollment. Leuk Lymphoma. 2019 Sep; 60(9):2190-2198. PMID: 30732497.
      View in: PubMed
    5. Muffly L, Li Q, Alvarez E, Kahn J, Winestone L, Cress R, Penn DC, Keegan THM. Hematopoietic Cell Transplantation in Young Adult Acute Lymphoblastic Leukemia: A United States Population-Level Analysis. J Adolesc Young Adult Oncol. 2019 Jun; 8(3):254-261. PMID: 30657424.
      View in: PubMed
    6. Li Y, Newton JG, Getz KD, Huang YS, Seif AE, Fisher BT, Aplenc R, Winestone LE. Comparable on-therapy mortality and supportive care requirements in Black and White patients following initial induction for pediatric acute myeloid leukemia. Pediatr Blood Cancer. 2019 Apr; 66(4):e27583. PMID: 30585685.
      View in: PubMed
    7. Winestone LE, Punn R, Tamaresis JS, Buckingham J, Pinsky BA, Waggoner JJ, Kharbanda S. High human herpesvirus 6 viral load in pediatric allogeneic hematopoietic stem cell transplant patients is associated with detection in end organs and high mortality. Pediatr Transplant. 2018 03; 22(2). PMID: 29181879.
      View in: PubMed
    8. Winestone LE, Getz KD, Miller TP, Li Y, Huang YS, Seif AE, Fisher BT, Aplenc R. Complications preceding early deaths in Black and White children with acute myeloid leukemia. Pediatr Blood Cancer. 2017 Dec; 64(12). PMID: 28727288.
      View in: PubMed
    9. Prince SD, Winestone LE, Nance SJ, Friedman DF. Recurrent Donath-Landsteiner hemolytic anemia: a pediatric case report. Transfusion. 2017 06; 57(6):1401-1406. PMID: 28369934.
      View in: PubMed
    10. Winestone LE, Getz KD, Miller TP, Wilkes JJ, Sack L, Li Y, Huang YS, Seif AE, Bagatell R, Fisher BT, Epstein AJ, Aplenc R. The role of acuity of illness at presentation in early mortality in black children with acute myeloid leukemia. Am J Hematol. 2017 Feb; 92(2):141-148. PMID: 27862214.
      View in: PubMed
    11. Chamberlain LJ, Pineda N, Winestone L, Saynina O, Rangaswami A, Link M, Wise PH. Increased utilization of pediatric specialty care: a population study of pediatric oncology inpatients in California. J Pediatr Hematol Oncol. 2014 Mar; 36(2):99-107. PMID: 24517965.
      View in: PubMed
    12. Winestone LE, Bukusi EA, Cohen CR, Kwaro D, Schmidt NC, Turan JM. Acceptability and feasibility of integration of HIV care services into antenatal clinics in rural Kenya: a qualitative provider interview study. Glob Public Health. 2012; 7(2):149-63. PMID: 22043837.
      View in: PubMed
    13. Bernstein WB, Cox JH, Aronson NE, Tracy L, Schlienger K, Ratto-Kim S, Garner R, Cotte J, Zheng Z, Winestone L, Liebig C, Galley LM, Connors M, Birx DL, Carroll RG, Levine BL. Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons. Clin Immunol. 2004 Jun; 111(3):262-74. PMID: 15183147.
      View in: PubMed