Kristin Shimano, MD

Title(s)Associate Professor, Pediatrics
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone415-476-3831
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    Collapse Biography 
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    Harvard UniversityM.D.2003School of Medicine
    University of California, San FranciscoResidency School of Medicine - Pediatrics

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Clinical features associated with thrombotic events in children with myeloproliferative neoplasms. Am J Hematol. 2022 09; 97(9):E353-E355. Shimano KA, Vanderpoel V, Stone H, Resar L, Kucine N. PMID: 35751861; PMCID: PMC9378702.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Eczema and Petechiae in an Infant. Pediatr Rev. 2022 07 01; 43(7):e19-e23. Lloyd-McLennan AM, Shimano KA, Dorsey M, Cordoro KM. PMID: 35773537.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. A pilot trial of prophylactic defibrotide to prevent serious thrombotic microangiopathy in high-risk pediatric patients. Pediatr Blood Cancer. 2022 05; 69(5):e29641. Higham CS, Shimano KA, Melton A, Kharbanda S, Chu J, Dara J, Winestone LE, Hermiston ML, Huang JN, Dvorak CC. PMID: 35253361.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    4. How we approach the use of sirolimus and new agents: Medical therapy to treat vascular anomalies. Pediatr Blood Cancer. 2022 08; 69 Suppl 3:e29603. Shimano KA, Eng W, Adams DM. PMID: 35253343.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Hematopoietic Cell Transplantation-Comorbidity Index Score Is Correlated with Treatment-Related Mortality and Overall Survival following Second Allogeneic Hematopoietic Cell Transplantation in Children. Transplant Cell Ther. 2022 03; 28(3):155.e1-155.e8. Forlanini F, Zinter MS, Dvorak CC, Bailey-Olson M, Winestone LE, Shimano KA, Higham CS, Melton A, Chu J, Kharbanda S. PMID: 34848362.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. An Unusual Presentation of Kaposiform Hemangioendothelioma in the Mandibular Bone. Blood. 2021 Nov 5; 138(Supplement 1):4205-4205. Rao RA, Ostedgaard OK, Zou ZY, Shimano SK. .
      View in: Publisher Site   Mentions:
    7. Angiographic Evidence of Response to Trametinib Therapy for a Spinal Cord Arteriovenous Malformation. . 2021 Sep 1; 2(3):e018. Cooke CD, Frieden FI, Shimano SK. .
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    8. Phase 3 randomised trial of eltrombopag versus standard first-line pharmacological management for newly diagnosed immune thrombocytopaenia (ITP) in children: study protocol. BMJ Open. 2021 08 27; 11(8):e044885. Shimano KA, Grace RF, Despotovic JM, Neufeld EJ, Klaassen RJ, Bennett CM, Ma C, London WB, Neunert C. PMID: 34452956; PMCID: PMC8404450.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    9. Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium. Am J Hematol. 2021 11 01; 96(11):1491-1504. Shimano KA, Narla A, Rose MJ, Gloude NJ, Allen SW, Bergstrom K, Broglie L, Carella BA, Castillo P, de Jong JLO, Dror Y, Geddis AE, Huang JN, Lau BW, McGuinn C, Nakano TA, Overholt K, Rothman JA, Sharathkumar A, Shereck E, Vlachos A, Olson TS, Bertuch AA, Wlodarski MW, Shimamura A, Boklan J. PMID: 34342889.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    10. Use of Complete Blood Cell Count Components to Screen for Hereditary Spherocytosis in Neonates. Pediatrics. 2021 09; 148(3). Weiss NM, Kuzniewicz MW, Shimano KA, Walsh EM, Newman TB. PMID: 34376530.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    11. Transplant-associated thrombotic microangiopathy in pediatric patients: pre-HSCT risk stratification and prophylaxis. Blood Adv. 2021 04 27; 5(8):2106-2114. Higham CS, Collins G, Shimano KA, Melton A, Kharbanda S, Winestone LE, Huang JN, Dara J, Long-Boyle JR, Dvorak CC. PMID: 33877298; PMCID: PMC8095147.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Quality of life is an important indication for second-line treatment in children with immune thrombocytopenia. Pediatr Blood Cancer. 2021 06; 68(6):e29023. Shimano KA, Neunert C, Bussel JB, Klaassen RJ, Bhat R, Pastore YD, Lambert MP, Bennett CM, Despotovic JM, Forbes P, Grace RF. PMID: 33764667.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231. Blood. 2020 Nov 5; 136(Supplement 1):11-12. Teachey TD, Devidas DM, Wood WB, Chen CZ, Hayashi HR, Annett AR, Asselin AB, August AK, Cho CS, Dunsmore DK, Fisher FB, Freedman FJ, Galardy GP, Harker-Murray HP, Hermiston HM, Horton HT, Jaju JA, Lam LA, Messinger MY, Miles MR, Okada OM, Patel PS, Schafer SE, Schechter-Finkelstein ST, Shimano SK, Singh SN, Steele SA, Sulis SM, Vargas VS, Winter WS, Wood WC, McKay MP, Bollard BC, Loh LM, Hunger HS, Raetz RE. .
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    14. A Pilot Trial of Pre-Transplant Risk Stratification and Prophylactic Defibrotide to Prevent Serious Thrombotic Microangiopathy in High-Risk Pediatric Hematopoietic Stem Cell Transplant Patients. Blood. 2020 Nov 5; 136(Supplement 1):9-10. Higham HC, Melton MA, Kharbanda KS, Dara DJ, Winestone WL, Huang HJ, Shimano SK. .
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    15. Monitoring Arteriovenous Malformation Response to Genotype-Targeted Therapy. Pediatrics. 2020 09; 146(3). Edwards EA, Phelps AS, Cooke D, Frieden IJ, Zapala MA, Fullerton HJ, Shimano KA. PMID: 32859736.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    16. Reduced Toxicity Conditioning for Nonmalignant Hematopoietic Cell Transplants. Biol Blood Marrow Transplant. 2020 09; 26(9):1646-1654. Contreras CF, Long-Boyle JR, Shimano KA, Melton A, Kharbanda S, Dara J, Higham C, Huang JN, Cowan MJ, Dvorak CC. PMID: 32534101.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Fatigue in children and adolescents with immune thrombocytopenia. Br J Haematol. 2020 10; 191(1):98-106. Grace RF, Klaassen RJ, Shimano KA, Lambert MP, Grimes A, Bussel JB, Breakey VR, Pastore YD, Black V, Overholt K, Bhat R, Forbes PW, Neunert C. PMID: 32501532.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    18. The impact of total body irradiation-based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2020 02; 67(2):e28079. Friend BD, Bailey-Olson M, Melton A, Shimano KA, Kharbanda S, Higham C, Winestone LE, Huang J, Stieglitz E, Dvorak CC. PMID: 31724815.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    19. A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children. Blood. 2019 Nov 13; 134(Supplement_1):2369-2369. Shimano SK, Grace GR, Bennett BC, Klaassen KR, Neunert NC, Neufeld NE, Ma MC, London LW, Despotovic DJ. .
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    20. Reduced Toxicity Conditioning for Non-Malignant Hematopoietic Cell Transplants. Blood. 2019 Nov 13; 134(Supplement_1):4481-4481. Contreras CC, Long-Boyle LJ, Shimano SK, Dara DJ, Huang HJ, Kharbanda KS, Melton MA, Higham HC, Cowan CM, Dvorak DC. .
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    21. Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis. Blood. 2019 Nov 13; 134(Supplement_1):3343-3343. Dain DA, Hermiston HM, Shimano SK, Kharbanda KS, Melton MA, Dara DJ, Huang HJ, Dvorak DC. .
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    22. Autoimmune Cytopenias in Pediatric Hematopoietic Cell Transplant Patients. Front Pediatr. 2019; 7:171. Neely JA, Dvorak CC, Pantell MS, Melton A, Huang JN, Shimano KA. PMID: 31131266; PMCID: PMC6509944.
      View in: PubMed   Mentions: 8  
    23. Second-line treatments in children with immune thrombocytopenia: Effect on platelet count and patient-centered outcomes. Am J Hematol. 2019 07; 94(7):741-750. Grace RF, Shimano KA, Bhat R, Neunert C, Bussel JB, Klaassen RJ, Lambert MP, Rothman JA, Breakey VR, Hege K, Bennett CM, Rose MJ, Haley KM, Buchanan GR, Geddis A, Lorenzana A, Jeng M, Pastore YD, Crary SE, Neier M, Neufeld EJ, Neu N, Forbes PW, Despotovic JM. PMID: 30945320; PMCID: PMC6527349.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    24. Transplant-Associated Thrombotic Microangiopathy in Pediatric Hematopoietic Cell Transplant Recipients: A Practical Approach to Diagnosis and Management. Front Pediatr. 2019; 7:133. Dvorak CC, Higham C, Shimano KA. PMID: 31024873; PMCID: PMC6465621.
      View in: PubMed   Mentions: 29  
    25. Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency. Biol Blood Marrow Transplant. 2019 07; 25(7):1355-1362. Dvorak CC, Long-Boyle J, Dara J, Melton A, Shimano KA, Huang JN, Puck JM, Dorsey MJ, Facchino J, Chang CK, Cowan MJ. PMID: 30876930; PMCID: PMC7384257.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsCTClinical Trials
    26. The Impact of Total Body Irradiation-Based Regimens on Outcomes in Children and Young Adults with Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation. 2019 Mar 1; 25(3):s197-s198. Friend FB, Bailey-Olson BM, Higham HC, Dara DJ, Melton MA, Shimano SK, Huang HJ, Kharbanda KS, Dvorak DC. .
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    27. Anemia and Neutropenia. . 2019 Jan 1; 443-448. Shimano SK. .
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    28. Daratumumab in life-threatening autoimmune hemolytic anemia following hematopoietic stem cell transplantation. Blood Adv. 2018 10 09; 2(19):2550-2553. Schuetz C, Hoenig M, Moshous D, Weinstock C, Castelle M, Bendavid M, Shimano K, Tolbert V, Schulz AS, Dvorak CC. PMID: 30291113; PMCID: PMC6177653.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    29. Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. Am J Hematol. 2018 07; 93(7):882-888. Grace RF, Despotovic JM, Bennett CM, Bussel JB, Neier M, Neunert C, Crary SE, Pastore YD, Klaassen RJ, Rothman JA, Hege K, Breakey VR, Rose MJ, Shimano KA, Buchanan GR, Geddis A, Haley KM, Lorenzana A, Thompson A, Jeng M, Neufeld EJ, Brown T, Forbes PW, Lambert MP. PMID: 29659042; PMCID: PMC6037544.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    30. Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children. bioRxiv. 2018 Mar 29; 291864. Zinter ZM, Dvorak DC, Mayday MM, Iwanaga IK, Ly LN, McGarry MM, Church CG, Faricy FL, Rowan RC, Hume HJ, Steiner SM, Crawford CE, Langelier LC, Kalantar KK, Chow CE, Miller MS, Shimano SK, Melton MA, Yanik YG, Sapru SA, DeRisi DJ. .
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    31. Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP). Blood. 2017 Dec 7; 130(Suppl_1):752-752. Grace GR, Klaassen KR, Bhat BR, Neier NM, Rose RM, Despotovic DJ, Bennett BC, Bussel BJ, Rothman RJ, Breakey BV, Hege HK, Shimano SK, Haley HK, Geddis GA, Buchanan BG, Lorenzano LA, Neunert NC, Jeng JM, Pastore PY, Crary CS, Neufeld NE, Neu NN, Forbes FP, Lambert LM. .
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    32. Sirolimus for management of complex vascular anomalies - A proposed dosing regimen for very young infants. Int J Pediatr Otorhinolaryngol. 2018 Feb; 105:48-51. Czechowicz JA, Long-Boyle JR, Rosbe KW, Mathes EF, Frieden IJ, Shimano KA. PMID: 29447818.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    33. JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias. Leukemia. 2017 12; 31(12):2568-2576. Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML. PMID: 28484265; PMCID: PMC5729333.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    34. JAK/STAT Pathway Inhibition Reverts IL7-Induced Glucocorticoid Resistance in a Subset of Human T-Cell Acute Lymphoblastic Leukemia. Blood. 2016 Dec 2; 128(22):3963-3963. Delgado-Martin DC, Shimano SK, Zinter ZM, Wahlstrom WJ, Smith SG, Taunton TJ, Winter WS, Roderick RJ, Kelliher KM, Horton HT, Wood WB, Teachey TD, Hermiston HM. .
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    35. Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study. Blood. 2016 Dec 2; 128(22):4752-4752. Vicky VB, Grace GR, Bennett BC, Despotovic DJ, Rothman RJ, Pastore PY, Neufeld NE, Klaassen KR, Lambert LM, Bussel BJ, Buchanan BG, Rose RM, Geddis GA, Shimano SK, Hege HK, Haley HK, Lorenzana LA, Thompson TA, Jeng JM, Crary CS, Neier NM, Brown BT, Forbes FP, Neunert NC. .
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    36. Daratumumab Is Effective in the Treatment of Refractory Post-Transplant Autoimmune Hemolytic Anemia: A Pediatric Case Report. Blood. 2016 Dec 2; 128(22):4819-4819. Tolbert TV, Goldsby GR, Huang HJ, Shimano SK, Melton MA, Willert WJ, Horn HB, Dvorak DC, Wahlstrom WJ. .
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    37. Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP. Blood. 2016 Dec 2; 128(22):1008-1008. Lambert LM, Grace GR, Neunert NC, Despotovic DJ, Bhat BR, Pastore PY, Buchanan BG, Klaassen KR, Bennett BC, Rothman RJ, Breakey BV, Bussel BJ, Rose RM, Geddis GA, Shimano SK, Hege HK, Haley HK, Lorenzana LA, Jeng JM, Crary CS, Neier NM, Brown BT, Forbes FP, Neufeld NE. .
      View in: Publisher Site   Mentions:
    38. Clinical Characteristics and Quality of Life of Children with ITP Starting Second Line Treatments: Data from the ITP Consortium of North America ICON1 Study. Blood. 2016 Dec 2; 128(22):249-249. Grace GR, Klaassen KR, Rothman RJ, Hege HK, Neufeld NE, Bennett BC, Lambert LM, Breakey BV, Bussel BJ, Buchanan BG, Rose RM, Geddis GA, Shimano SK, Haley HK, Lorenzana LA, Neunert NC, Thompson TA, Pastore PY, Jeng JM, Crary CS, Neier NM, Brown BT, Forbes FP, Despotovic DJ. .
      View in: Publisher Site   Mentions:
    39. Thrombopoietin Receptor Agonist Use in Children: Data From the Pediatric ITP Consortium of North America ICON2 Study. Pediatr Blood Cancer. 2016 08; 63(8):1407-13. Neunert C, Despotovic J, Haley K, Lambert MP, Nottage K, Shimano K, Bennett C, Klaassen R, Stine K, Thompson A, Pastore Y, Brown T, Forbes PW, Grace RF, Pediatric ITP Consortium of North America (ICON). PMID: 27135461; PMCID: PMC5718620.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    40. Autoimmune Cytopenias in Pediatric Hematopoietic Cell Transplant (HCT) Patients. Biology of Blood and Marrow Transplantation. 2016 Mar 1; 22(3):s255. Neely NJ, Dvorak DC, Pantell PM, Shimano SK. .
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    41. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 2012 Jan 11; 481(7380):157-63. Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG. PMID: 22237106; PMCID: PMC3267575.
      View in: PubMed   Mentions: 811     Fields:    Translation:HumansCells
    42. Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project. Blood. 2011 Nov 18; 118(21):68-68. Zhang ZJ, Ding DL, Holmfeldt HL, Wu WG, Heatley HS, Payne-Turner PD, Easton EJ, Chen CX, Wang WJ, Rusch RM, Lu LC, Chen CS, Collins-Underwood CR, Ma MJ, Roberts RK, Pounds PS, Wei WL, Ulyanov UA, Becksfort BJ, Gupta GP, Huether HR, Kriwacki KR, McGoldrick MD, Zhao ZD, Alford AD, Espy ES, Bobba BK, Song SG, Pei PD, Cheng CC, Roberts RS, Barbato BM, Campana CD, Coustan-Smith CE, Evans EW, Shurtleff SS, Kleppe KM, Cools CJ, Shimano SK, Hermiston HM, Doulatov DS, Eppert EK, Laurenti LE, Notta NF, Dick DJ, Basso BG, Hunger HS, Loh LM, Devidas DM, Wood WB, Winter WS, Dunsmore DK, Fulton FR, Fulton FL, Hong HX, Harris HC, Dooling DD, Ochoa OK, Johnson JK, Obenauer OJ, Pui PC, Raimondi RS, Naeve NC, Ley LT, Mardis ME, Wilson WR, Downing DJ, Mullighan MC. .
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