Kristin Shimano, MD

Title(s)Associate Professor, Pediatrics
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone415-476-3831
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    Collapse Biography 
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    Harvard UniversityM.D.2003School of Medicine
    University of California, San FranciscoResidency School of Medicine - Pediatrics

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Angiographic Evidence of Response to Trametinib Therapy for a Spinal Cord Arteriovenous Malformation. . 2021 Sep 1; 2(3):e018. Daniel L. Cooke, Ilona J. Frieden, Kristin A. Shimano. .
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    2. Phase 3 randomised trial of eltrombopag versus standard first-line pharmacological management for newly diagnosed immune thrombocytopaenia (ITP) in children: study protocol. BMJ Open. 2021 08 27; 11(8):e044885. Shimano KA, Grace RF, Despotovic JM, Neufeld EJ, Klaassen RJ, Bennett CM, Ma C, London WB, Neunert C. PMID: 34452956.
      View in: PubMed   Mentions:    Fields:    
    3. Use of Complete Blood Cell Count Components to Screen for Hereditary Spherocytosis in Neonates. Pediatrics. 2021 Sep; 148(3). Weiss NM, Kuzniewicz MW, Shimano KA, Walsh EM, Newman TB. PMID: 34376530.
      View in: PubMed   Mentions:    Fields:    
    4. Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium. Am J Hematol. 2021 Aug 03. Shimano KA, Narla A, Rose MJ, Gloude NJ, Allen SW, Bergstrom K, Broglie L, Carella BA, Castillo P, de Jong JLO, Dror Y, Geddis AE, Huang JN, Lau BW, McGuinn C, Nakano TA, Overholt K, Rothman JA, Sharathkumar A, Shereck E, Vlachos A, Olson TS, Bertuch AA, Wlodarski MW, Shimamura A, Boklan J. PMID: 34342889.
      View in: PubMed   Mentions:    Fields:    
    5. Transplant-associated thrombotic microangiopathy in pediatric patients: pre-HSCT risk stratification and prophylaxis. Blood Adv. 2021 04 27; 5(8):2106-2114. Higham CS, Collins G, Shimano KA, Melton A, Kharbanda S, Winestone LE, Huang JN, Dara J, Long-Boyle JR, Dvorak CC. PMID: 33877298.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Quality of life is an important indication for second-line treatment in children with immune thrombocytopenia. Pediatr Blood Cancer. 2021 Jun; 68(6):e29023. Shimano KA, Neunert C, Bussel JB, Klaassen RJ, Bhat R, Pastore YD, Lambert MP, Bennett CM, Despotovic JM, Forbes P, Grace RF. PMID: 33764667.
      View in: PubMed   Mentions: 1     Fields:    
    7. Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231. Blood. 2020 Nov 5; 136(Supplement 1):11-12. David T. Teachey, Meenakshi Devidas, Brent L Wood, Zhiguo Chen, Robert James Hayashi, Robert D Annett, Barbara L Asselin, Keith J August, Steve Y Cho, Kimberly P. Dunsmore, Brian T. Fisher, Jason L. Freedman, Paul J. Galardy, Paul Harker-Murray, Michelle L. Hermiston, Terzah M Horton, Alok I Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir I Patel, Eric S. Schafer, Tal Schechter-Finkelstein, Kristin A. Shimano, Neelam Singh, Amii C. Steele, Maria L. Sulis, Sarah L Vargas, Stuart S. Winter, Charlotte Wood, Patrick Zweider McKay, Catherine M. Bollard, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz. .
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    8. A Pilot Trial of Pre-Transplant Risk Stratification and Prophylactic Defibrotide to Prevent Serious Thrombotic Microangiopathy in High-Risk Pediatric Hematopoietic Stem Cell Transplant Patients. Blood. 2020 Nov 5; 136(Supplement 1):9-10. Christine S Higham, Alexis Melton, Sandhya Kharbanda, Jasmeen Dara, Lena E. Winestone, James N Huang, Kristin A. Shimano. .
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    9. Monitoring Arteriovenous Malformation Response to Genotype-Targeted Therapy. Pediatrics. 2020 09; 146(3). Edwards EA, Phelps AS, Cooke D, Frieden IJ, Zapala MA, Fullerton HJ, Shimano KA. PMID: 32859736.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    10. Reduced Toxicity Conditioning for Nonmalignant Hematopoietic Cell Transplants. Biol Blood Marrow Transplant. 2020 09; 26(9):1646-1654. Contreras CF, Long-Boyle JR, Shimano KA, Melton A, Kharbanda S, Dara J, Higham C, Huang JN, Cowan MJ, Dvorak CC. PMID: 32534101.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Fatigue in children and adolescents with immune thrombocytopenia. Br J Haematol. 2020 10; 191(1):98-106. Grace RF, Klaassen RJ, Shimano KA, Lambert MP, Grimes A, Bussel JB, Breakey VR, Pastore YD, Black V, Overholt K, Bhat R, Forbes PW, Neunert C. PMID: 32501532.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    12. The impact of total body irradiation-based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2020 02; 67(2):e28079. Friend BD, Bailey-Olson M, Melton A, Shimano KA, Kharbanda S, Higham C, Winestone LE, Huang J, Stieglitz E, Dvorak CC. PMID: 31724815.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children. Blood. 2019 Nov 13; 134(Supplement_1):2369-2369. Kristin A. Shimano, Rachael F. Grace, Carolyn M. Bennett, Robert J Klaassen, Cindy Neunert, Ellis J. Neufeld, Clement Ma, Wendy B. London, Jenny M. Despotovic. .
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    14. Reduced Toxicity Conditioning for Non-Malignant Hematopoietic Cell Transplants. Blood. 2019 Nov 13; 134(Supplement_1):4481-4481. Cristina F Contreras, Janel R Long-Boyle, Kristin A. Shimano, Jasmeen Dara, James N Huang, Sandhya Kharbanda, Alexis Melton, Christine Higham, Morton J Cowan, Christopher C. Dvorak. .
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    15. Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis. Blood. 2019 Nov 13; 134(Supplement_1):3343-3343. Aleksandra S. Dain, Michelle L. Hermiston, Kristin A. Shimano, Sandhya Kharbanda, Alexis Melton, Jasmeen Dara, James N Huang, Christopher C. Dvorak. .
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    16. Autoimmune Cytopenias in Pediatric Hematopoietic Cell Transplant Patients. Front Pediatr. 2019; 7:171. Neely JA, Dvorak CC, Pantell MS, Melton A, Huang JN, Shimano KA. PMID: 31131266.
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    17. Second-line treatments in children with immune thrombocytopenia: Effect on platelet count and patient-centered outcomes. Am J Hematol. 2019 07; 94(7):741-750. Grace RF, Shimano KA, Bhat R, Neunert C, Bussel JB, Klaassen RJ, Lambert MP, Rothman JA, Breakey VR, Hege K, Bennett CM, Rose MJ, Haley KM, Buchanan GR, Geddis A, Lorenzana A, Jeng M, Pastore YD, Crary SE, Neier M, Neufeld EJ, Neu N, Forbes PW, Despotovic JM. PMID: 30945320.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    18. Transplant-Associated Thrombotic Microangiopathy in Pediatric Hematopoietic Cell Transplant Recipients: A Practical Approach to Diagnosis and Management. Front Pediatr. 2019; 7:133. Dvorak CC, Higham C, Shimano KA. PMID: 31024873.
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    19. Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency. Biol Blood Marrow Transplant. 2019 07; 25(7):1355-1362. Dvorak CC, Long-Boyle J, Dara J, Melton A, Shimano KA, Huang JN, Puck JM, Dorsey MJ, Facchino J, Chang CK, Cowan MJ. PMID: 30876930.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    20. The Impact of Total Body Irradiation-Based Regimens on Outcomes in Children and Young Adults with Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation. 2019 Mar 1; 25(3):s197-s198. Brian D. Friend, Mara Bailey-Olson, Christine Higham, Jasmeen Dara, Alexis Melton, Kristin A. Shimano, James Huang, Sandhya Kharbanda, Christopher C. Dvorak. .
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    21. Anemia and Neutropenia. . 2019 Jan 1; 443-448. Kristin Shimano. .
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    22. Daratumumab in life-threatening autoimmune hemolytic anemia following hematopoietic stem cell transplantation. Blood Adv. 2018 10 09; 2(19):2550-2553. Schuetz C, Hoenig M, Moshous D, Weinstock C, Castelle M, Bendavid M, Shimano K, Tolbert V, Schulz AS, Dvorak CC. PMID: 30291113.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    23. Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. Am J Hematol. 2018 07; 93(7):882-888. Grace RF, Despotovic JM, Bennett CM, Bussel JB, Neier M, Neunert C, Crary SE, Pastore YD, Klaassen RJ, Rothman JA, Hege K, Breakey VR, Rose MJ, Shimano KA, Buchanan GR, Geddis A, Haley KM, Lorenzana A, Thompson A, Jeng M, Neufeld EJ, Brown T, Forbes PW, Lambert MP. PMID: 29659042.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    24. Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children. bioRxiv. 2018 Mar 29; 291864. Matt S Zinter, Christopher C Dvorak, Madeline Y Mayday, Kensho Iwanaga, Ngoc P Ly, Meghan E McGarry, Gwynne D Church, Lauren E Faricy, Courtney M Rowan, Janet R Hume, Marie E Steiner, Emily D Crawford, Charles Langelier, Katrina Kalantar, Eric D Chow, Steve Miller, Kristin Shimano, Alexis Melton, Greg A Yanik, Anil Sapru, Joseph L DeRisi. .
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    25. Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP). Blood. 2017 Dec 7; 130(Suppl_1):752-752. Rachael F. Grace, Robert J Klaassen, Rukhmi Bhat, Michelle Neier, Melissa J. Rose, Jenny M. Despotovic, Carolyn M. Bennett, James B. Bussel, Jennifer A. Rothman, Vicky R. Breakey, Kerry Hege, Kristin A. Shimano, Kristina M. Haley, Amy E. Geddis, George R. Buchanan, Adonis Lorenzano, Cindy Neunert, Michael R. Jeng, Yves D. Pastore, Shelley Crary, Ellis J Neufeld, Nolan Neu, Peter Forbes, Michele P. Lambert. .
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    26. Sirolimus for management of complex vascular anomalies - A proposed dosing regimen for very young infants. Int J Pediatr Otorhinolaryngol. 2018 Feb; 105:48-51. Czechowicz JA, Long-Boyle JR, Rosbe KW, Mathes EF, Frieden IJ, Shimano KA. PMID: 29447818.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias. Leukemia. 2017 12; 31(12):2568-2576. Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML. PMID: 28484265.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    28. JAK/STAT Pathway Inhibition Reverts IL7-Induced Glucocorticoid Resistance in a Subset of Human T-Cell Acute Lymphoblastic Leukemia. Blood. 2016 Dec 2; 128(22):3963-3963. Cristina Delgado-Martin, Kristin Shimano, Matthew S Zinter, Justin T. Wahlstrom, Geoffrey A. Smith, Jack Taunton, Stuart S. Winter, Justine E. Roderick, Michelle Kelliher, Terzah M. Horton, Brent L. Wood, David T Teachey, Michelle L. Hermiston. .
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    29. Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study. Blood. 2016 Dec 2; 128(22):4752-4752. Breakey R. Vicky, Rachael F Grace, Carolyn M. Bennett, Jenny M. Despotovic, Jennifer A Rothman, Yves D. Pastore, Ellis J Neufeld, Robert J. Klaassen, Michele Lambert, James B. Bussel, George R. Buchanan, Melissa J. Rose, Amy E. Geddis, Kristin Shimano, Kerry Hege, Kristina M. Haley, Adonis Lorenzana, Alexis A. Thompson, Michael Jeng, Shelley E. Crary, Michelle Neier, Travis Brown, Peter Forbes, Cindy Neunert. .
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    30. Daratumumab Is Effective in the Treatment of Refractory Post-Transplant Autoimmune Hemolytic Anemia: A Pediatric Case Report. Blood. 2016 Dec 2; 128(22):4819-4819. Vanessa P. Tolbert, Robert Goldsby, James Huang, Kristin Shimano, Alexis Melton, Jennifer Willert, Biljana N. Horn, Christopher C. Dvorak, Justin T. Wahlstrom. .
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    31. Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP. Blood. 2016 Dec 2; 128(22):1008-1008. Michele P. Lambert, Rachael F Grace, Cindy Neunert, Jenny M. Despotovic, Rukhmi Bhat, Yves D. Pastore, George R. Buchanan, Robert J. Klaassen, Carolyn M. Bennett, Jennifer A Rothman, Vicky R. Breakey, James B. Bussel, Melissa J. Rose, Amy Geddis, Kristin Shimano, Kerry Hege, Kristina M. Haley, Adonis Lorenzana, Michael Jeng, Shelley E. Crary, Michelle Neier, Travis Brown, Peter Forbes, Ellis J Neufeld. .
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    32. Clinical Characteristics and Quality of Life of Children with ITP Starting Second Line Treatments: Data from the ITP Consortium of North America ICON1 Study. Blood. 2016 Dec 2; 128(22):249-249. Rachael F Grace, Robert J. Klaassen, Jennifer A Rothman, Kerry Hege, Ellis J Neufeld, Carolyn M. Bennett, Michele Lambert, Vicky R. Breakey, James B. Bussel, George R. Buchanan, Melissa J. Rose, Amy Geddis, Kristin Shimano, Kristina M. Haley, Adonis Lorenzana, Cindy Neunert, Alexis A. Thompson, Yves D. Pastore, Michael Jeng, Shelley E. Crary, Michelle Neier, Travis Brown, Peter Forbes, Jenny M. Despotovic. .
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    33. Thrombopoietin Receptor Agonist Use in Children: Data From the Pediatric ITP Consortium of North America ICON2 Study. Pediatr Blood Cancer. 2016 08; 63(8):1407-13. Neunert C, Despotovic J, Haley K, Lambert MP, Nottage K, Shimano K, Bennett C, Klaassen R, Stine K, Thompson A, Pastore Y, Brown T, Forbes PW, Grace RF, Pediatric ITP Consortium of North America (ICON) . PMID: 27135461.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    34. Autoimmune Cytopenias in Pediatric Hematopoietic Cell Transplant (HCT) Patients. Biology of Blood and Marrow Transplantation. 2016 Mar 1; 22(3):s255. Jessica Neely, Christopher C. Dvorak, Matthew Pantell Pantell, Kristin A. Shimano. .
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    35. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 2012 Jan 11; 481(7380):157-63. Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG. PMID: 22237106.
      View in: PubMed   Mentions: 674     Fields:    Translation:HumansCells
    36. Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project. Blood. 2011 Nov 18; 118(21):68-68. Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Susan L. Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch, Charles Lu, Shann-Ching Chen, Racquel Collins-Underwood, Jing Ma, Kathryn G. Roberts, Stanley Pounds, Lei Wei, Anatoly Ulyanov, Jared Becksfort, Pankaj Gupta, Robert Huether, Richard Kriwacki, Daniel McGoldrick, David Zhao, Daniel Alford, Stephen Espy, Kiran Chand Bobba, Guangchun Song, Deqing Pei, Cheng Cheng, Stefan Roberts, Michael Barbato, Dario Campana, Elaine Coustan-Smith, William E. Evans, Sheila A Shurtleff, Maria Kleppe, Jan Cools, Kristin Shimano, Michelle L. Hermiston, Sergei Doulatov, Kolja Eppert, Elisa Laurenti, Faiyaz Notta, John E Dick, Giuseppe Basso, Stephen P. Hunger, Mignon L Loh, Meenakshi Devidas, Brent L. Wood, Stuart S. Winter, Kimberly Dunsmore, Robert S. Fulton, Lucinda A. Fulton, Xin Hong, Christopher C. Harris, David J. Dooling, Kerri Ochoa, Kimberly J Johnson, John C Obenauer, Ching-Hon Pui, Susana C. Raimondi, Clayton W Naeve, Timothy J Ley, Elaine R Mardis, Richard K Wilson, James R Downing, Charles G Mullighan. .
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