Kristin Shimano, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
Address550 16th Street, #4650
San Francisco CA 94158
Phone415-476-3831
PronounsShe/Her/Hers
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    Collapse Biography 
    Collapse education and training
    Harvard UniversityM.D.2003School of Medicine
    University of California, San FranciscoResidency 2006School of Medicine - Pediatrics
    Boston Children's Hospital/Dana Farber Cancer InstituteFellowshipPediatric Hematology/Oncology
    University of California, San FranciscoFellowship2010Pediatric Hematology/Oncology

    Collapse Overview 

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. High Melphalan Exposure Increases the Risk of Graft-versus-Host Disease in Pediatric Patients Undergoing Alpha-Beta T-Cell Depleted Haploidentical Transplantation. Transplant Cell Ther. 2025 Apr 02. Dvorak CC, Cho S, Cisneros GS, Higham CS, Chu J, Winestone LE, Temple WC, Kharbanda S, Shimano KA, Avagyan S, Pauerstein PT, Huang JN, Cheng G, Lalefar N, Aguayo-Hiraldo P, Keizer RJ, Pulsipher MA, Long-Boyle JR. PMID: 40185404.
      View in: PubMed   Mentions:    Fields:    
    2. Working toward international consensus defining pediatric "refractory ITP". Blood Adv. 2025 Mar 11; 9(5):1244-1245. O'Farrell C, Bell Grimes A, Nakano TA, Klaassen RJ, Lambert MP, Neunert C, Rothman JA, Shimano KA, Grace RF. PMID: 39787601; PMCID: PMC11993825.
      View in: PubMed   Mentions: 1     Fields:    
    3. Younger children with nonmalignant disease have increased incidence of mixed myeloid chimerism after allogeneic hematopoietic cell transplantation with busulfan-based conditioning. Transplant Cell Ther. 2025 Apr; 31(4):259.e1-259.e15. Dvorak CC, Temple WC, Cisneros GS, Chu J, Winestone LE, Higham CS, Shimano KA, Kharbanda S, Avagyan S, Pauerstein P, Huang JN, Cheng G, Waters E, Winger BA, Cowan MJ, Long-Boyle JR. PMID: 39938805.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Younger Children Have Increased Mixed Myeloid Chimerism with Busulfan-Based Conditioning for Hematopoietic Cell Transplantation of Non-Malignant Disease. Transplantation and Cellular Therapy. 2025 Feb 1; 31(2):s179-s180. Dvorak DC, Temple TW, Cisneros CG, Chu CJ, Winestone WL, Higham HC, Shimano SK, Kharbanda KS, Avagyan AS, Hermiston HM, Huang HJ, Long-Boyle LJ. .
      View in: Publisher Site   Mentions:
    5. High Exposure of Intravenous Alemtuzumab Is Associated with Increased Risk of Double-Stranded DNA Viral Infections in Patients with Non-Malignant Disease Undergoing Allogeneic HCT. Transplantation and Cellular Therapy. 2025 Feb 1; 31(2):s186. Cisneros CG, Long-Boyle LJ, Temple TW, Chu CJ, Avagyan AS, Winestone WL, Higham HC, Shimano SK, Huang HJ, Hermiston HM, Kharbanda KS, Dvorak DC. .
      View in: Publisher Site   Mentions:
    6. Hematopoietic Cell Transplantation for Wiskott-Aldrich Syndrome - Impact of Age, Donor, and Infection: A Pidtc Report. Transplantation and Cellular Therapy. 2025 Feb 1; 31(2):s39-s41. Alexander AJ, Saldana SB, Brazauskas BR, Dammalapati DS, Griffith GL, Shah SA, Shimano SK, Ochs OH, Bleesing BJ, Ebens EC, Kapadia KM, Dvorak DC, Bauchat BA, Kapoor KN, Oved OJ, Eissa EH, Lust LH, Keller KM, Haines HH, Chandrakasan CS, Talano TJ, Rayes RA, Madden ML, Shereck SE, Miller MH, Satter SL, Martinez MC, Rozmus RJ, Bednarski BJ, Yu YL, Haddad HE, Chellapandian CD, Aquino AV, Knutsen KA, Chong CH, Chopek CA, Gillio GA, Joshi JA, Rangarajan RH, Moore MT, Heimall HJ, Andolina AJ, DeSantes DK, VanderLugt VM, Prockop PS, Shyr SD, Sullivan SK, Parikh PS, Weinacht WK, Torgerson TT, Marsh MR, Pulsipher PM, Leiding LJ, Kohn KD, Puck PJ, Notarangelo NL, Rawlings RD, Cowan CM, Petrovic PA, Pai PS, Burroughs BL, Chan CA. .
      View in: Publisher Site   Mentions:
    7. Fludarabine Pharmacokinetic-Model-Based Dosing Minimizes the Risk of Graft Rejection in Pediatric Patients Undergoing Mismatched Allogeneic Hematopoietic Cell Transplantation. Transplantation and Cellular Therapy. 2025 Feb 1; 31(2):s173-s174. Dvorak DC, Temple TW, Cisneros CG, Chu CJ, Winestone WL, Higham HC, Shimano SK, Kharbanda KS, Avagyan AS, Hermiston HM, Huang HJ, Long-Boyle LJ. .
      View in: Publisher Site   Mentions:
    8. Genetic variants in canonical Wnt signaling pathway associated with pediatric immune thrombocytopenia. Blood Adv. 2024 11 12; 8(21):5529-5538. Kim TO, Geris JM, Flanagan JM, Grace RF, Lambert MP, O'Farrell C, Rose MJ, Shimano KA, Niss O, Neunert C, Nakano TA, MacMath D, Dinu B, Kirk SE, Neufeld EJ, Despotovic JM, Scheurer ME, Grimes AB. PMID: 39189922; PMCID: PMC11538615.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Effective Use of ALK Inhibitors in EML4::ALK-Positive Lymphatic Malformations. Pediatr Blood Cancer. 2025 Feb; 72(2):e31441. Apsel Winger B, Dowd CF, Shimano KA, Devine WP, Mathes E, Frieden I, Schaefer C, Kothari A. PMID: 39529238.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Pediatric Autoimmune Hemolytic Anemia Is Associated with a High Incidence of an Underlying Immune Disorder and High Mortality Rate. Blood. 2024 Nov 5; 144(Supplement 1):795. Grace GR, Steele SM, Kalashnikova KT, Bloom BE, Khan KA, Badawy BS, Elkus EH, Breakey BV, Pavalagantharajah PS, Lilla LS, Leister LJ, Kochhar KM, Hillier HK, Phillips PL, Chumsky CJ, Klaassen KR, Ghanem GD, Charland CD, Nakano NT, Kalter KJ, Remiker RA, Rothman RJ, McComb MC, Guedes GB, Shah SS, Everly EC, Shimano SK, Matsunaga MA, Tiu TG, Valle VR, Nataraj NS, Rifkin-Zenenberg RS, Tavares TE, Montcrieff MC, Harris HE, Chen CN, London LW, Lambert LM. .
      View in: Publisher Site   Mentions:
    11. Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children. Blood. 2024 Nov 5; 144(Supplement 1):709-709. Shimano SK, Grimes GA, Rose RM, Kaicker KS, Shah SS, Briones BM, Gunn GE, Nakano NT, Lebensburger LJ, Lambert LM, Fritch Lilla FS, Jesudas JR, Lee-Miller LC, Thompson TA, Bhat BR, Rifkin-Zenenberg RS, Majumdar MS, Kochhar KM, Crary CS, Hege HK, Rothman RJ, Ford FJ, Bies BJ, Fort FJ, Hsieh HL, Ruiz RM, Carrier CK, Dinu DB, Wong WJ, Kao KP, London LW, Arnold AS, Bennett BC, Despotovic DJ, Klaassen KR, Neufeld NE, Neunert NC, Grace GR. .
      View in: Publisher Site   Mentions:
    12. What is in a name: defining pediatric refractory ITP. Blood Adv. 2024 10 08; 8(19):5112-5117. Nakano TA, Grimes AB, Klaassen RJ, Lambert MP, Neunert C, Rothman JA, Shimano KA, Amend C, Askew M, Badawy SM, Baker JM, Breakey V, Crary S, Davini M, Fritch Lilla S, Gilbert M, Hays T, Hege K, Hillier K, Jacobson-Kelly A, Kaicker S, Kim TO, Kochhar M, Leblanc T, Martinelli M, Nunez M, Remiker A, Schultz C, Sharma R, Grace RF. PMID: 39059013; PMCID: PMC11460440.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Cyclophosphamide and Thiotepa Increases Risk of Transplant-Associated Thrombotic Microangiopathy. Transplant Cell Ther. 2024 Sep; 30(9):931.e1-931.e10. Higham CS, Shimano KA, Kharbanda S, Chu J, Cisneros GS, Winestone LE, Dara J, Huang JN, Hermiston ML, Long-Boyle JR, Dvorak CC. PMID: 38944154.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Treatment of relapsed/refractory severe aplastic anemia in children: Evidence-based recommendations. Pediatr Blood Cancer. 2024 Aug; 71(8):e31075. Shimano KA, Sasa G, Broglie L, Gloude NJ, Myers K, Nakano TA, Sharathkumar A, Rothman JA, Pereda MA, Overholt K, Narla A, McGuinn C, Lau BW, Geddis AE, Dror Y, de Jong JLO, Castillo P, Allen SW, Boklan J. PMID: 38764170.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. MRD at the end of induction and EFS in T-cell lymphoblastic lymphoma: Children's Oncology Group trial AALL1231. Blood. 2024 05 16; 143(20):2053-2058. Hayashi RJ, Hermiston ML, Wood BL, Teachey DT, Devidas M, Chen Z, Annett RD, Asselin BL, August K, Cho S, Dunsmore KP, Freedman JL, Galardy PJ, Harker-Murray P, Horton TM, Jaju A, Lam A, Messinger YH, Miles RR, Okada M, Patel S, Schafer ES, Schechter T, Shimano KA, Singh N, Steele A, Sulis ML, Vargas SL, Winter SS, Wood C, Zweidler-McKay PA, Loh ML, Hunger SP, Raetz EA, Bollard CM, Allen CE. PMID: 38457359; PMCID: PMC11143515.
      View in: PubMed   Mentions: 1     Fields:    Translation:CTClinical Trials
    16. Treatment of newly diagnosed severe aplastic anemia in children: Evidence-based recommendations. Pediatr Blood Cancer. 2024 Aug; 71(8):e31070. Shimano KA, Rothman JA, Allen SW, Castillo P, de Jong JLO, Dror Y, Geddis AE, Lau BW, McGuinn C, Narla A, Overholt K, Pereda MA, Sharathkumar A, Sasa G, Nakano TA, Myers K, Gloude NJ, Broglie L, Boklan J. PMID: 38757488.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. 13 Long-Term Medical Management of Patients with Chronic Granulomatous Disease, Wiskott-Aldrich Syndrome, and Primary Immune Regulatory Disorders: A Primary Immune Deficiency Treatment Consortium Survey. Clinical Immunology. 2024 May 1; 262:109955. Deal DC, Lim LS, Ishikawa IK, Tsalatsanis TA, Ochfeld OE, Petrovic PA, Mallhi MK, Joshi JA, Shimano SK, Dvorak DC, Haddad HE, Kohn KD, Griffith GL, Notarangelo NL, Pulsipher PM, Cowan CM, Pai PS, Puck PJ, Burroughs BL, Heimall HJ, Leiding LJ. .
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    18. 169 Long Term Management of Transplanted Patients with Chronic Granulomatous Disease, Wiskott-Aldrich Syndrome, and Primary Immune Regulatory Disorders: A PIDTC Survey. Clinical Immunology. 2024 May 1; 262:110111. Lim LS, Deal DC, Ishikawa IK, Tsalatsanis TA, Ochfeld OE, Petrovic PA, Mallhi MK, Joshi JA, Shimano SK, Dvorak DC, Haddad HE, Kohn KD, Griffith GL, Notarangelo NL, Pulsipher PM, Cowan CM, Pai PS, Puck PJ, Leiding LJ, Heimall HJ, Burroughs BL. .
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    19. Diagnosing and Grading of Sinusoidal Obstructive Syndrome after Hematopoietic Stem Cell Transplant of Children, Adolescent and Young Adults treated in a Pediatric Institution with Pediatric Protocols. Transplant Cell Ther. 2024 Jul; 30(7):690.e1-690.e16. Salinas Cisneros G, Dvorak CC, Long-Boyle J, Kharbanda S, Shimano KA, Melton A, Chu J, Winestone LE, Dara J, Huang JN, Hermiston ML, Zinter M, Higham CS. PMID: 38631464.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. A Napaac Survey to Understand Practices in Diagnosis and Treatment of Children with Moderate Aplastic Anemia. Blood. 2023 Nov 28; 142(Supplement 1):5642. Castillo CP, Omer OL, Allen AS, Barpujari BA, Gloude GN, McGuinn MC, Nakano NT, Ogando-Rivas OE, Overholt OK, Shimano SK, Vlachos VA, Kurre KP, de Jong dJ. .
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    21. A Novel Online Decision Support Tool to Determine Practice Patterns and Concordance with Experts in the Treatment of Patients with Immune Thrombocytopenia. Blood. 2023 Nov 28; 142(Supplement 1):5046. Olin OJ, Broome BC, Panch PS, Rosenthal RK, Quill QT, Shimano SK, Al-Samkari AH. .
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    22. A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update. Blood. 2023 Nov 28; 142(Supplement 1):1223. Grimes GA, Grace GR, Rose RM, Shah SS, Kaicker KS, Bennett BC, Briones BM, Nakano NT, Lilla LS, Lebensburger LJ, Thompson TA, Bhat BR, Jesudas JR, Lambert LM, Crary CS, Hege HK, Lee-Miller LC, Majumdar MS, Ford FJ, Bies BJ, Black BV, Fort FJ, Kochhar KM, Wong WJ, Dinu DB, Kao KP, London LW, Despotovic DJ, Klaassen KR, Neufeld NE, Neunert NC, Shimano SK. .
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    23. Genetic Variants in Canonical Wnt Signaling Pathway Associated with Pediatric ITP. Blood. 2023 Nov 28; 142(Supplement 1):2593. Kim KT, Geris GJ, Grimes GA, Grace GR, Lambert LM, Rose RM, Shimano SK, Niss NO, Neunert NC, Nakano NT, Macmath MD, Dinu DB, Kirk KS, Despotovic DJ, Flanagan FJ, Scheurer SM. .
      View in: Publisher Site   Mentions:
    24. EML4::ALK fusions in complex lymphatic malformations. Pediatr Blood Cancer. 2023 Jun 28; e30516. Apsel Winger B, Devine WP, Hsiao EC, Zapala M, Van Ziffle J, Gupta N, Frieden IJ, Shimano KA. PMID: 37377128.
      View in: PubMed   Mentions:    Fields:    
    25. 345 Prophylactic Tocilizumab Decreases Incidence of Acute Graft-Versus-Host Disease Following Alpha/Beta T-Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation in Children and Young Adults. Transplantation and Cellular Therapy. 2023 Feb 1; 29(2):s263-s264. Cho CS, Dvorak DC, Higham HC, Cisneros CG, Chu CJ, Melton MA, Winestone WL, Shimano SK, Dara DJ, Hermiston HM, Huang HJ, Long-Boyle LJ, Kharbanda KS. .
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    26. 172 Diagnosing and Grading of SOS: Which Criteria Are Best?. Transplantation and Cellular Therapy. 2023 Feb 1; 29(2):s138-s139. Cisneros CG, Dvorak DC, Kharbanda KS, Shimano SK, Melton MA, Chu CJ, Winestone WL, Dara DJ, Huang HJ, Hermiston HM, Higham HC. .
      View in: Publisher Site   Mentions:
    27. 62 Immunohematologic Disorders. Clinical Immunology. 2023 Jan 1; 796-805. Shimano SK, Noel NP. .
      View in: Publisher Site   Mentions:
    28. Current practices in pediatric hospital-acquired thromboembolism: Survey of the Children's Hospital Acquired Thrombosis (CHAT) Consortium. Res Pract Thromb Haemost. 2022 Oct; 6(7):e12793. Abrams CM, Jaffray J, Stillings A, Branchford BR, Young G, Goldenberg NA, Abajas YL, CHAT Consortium Investigators, VTE Risk Factors and Thromboprophylaxis Working Group of the Pediatric and Neonatal Thrombosis and H, Fargo J, Crary S, Kumar R, Woods G, Narang S, Cooper J, Silvey M, Garland K, Mahajerin A, Luchtman-Jones L, Torres M, Wright J, Pahl K, Armstrong K, Braunreiter C, Bakeer N, Sochet A, Hogan M, Gupta S, Knoll C, Hege K, Schaefer B, Panigrahi A, Thornburg C, Shimano K, Ahuja S, Weyand A, Boucher A, Abajas Y, Subbaswamy A, Khan O, Druzgal C, Maida D, Wheeler A, Malec L, Branchford B, Kucine NE, Prozora S. PMID: 38024326; PMCID: PMC10656282.
      View in: PubMed   Mentions: 1  
    29. Correlation of Minimal Residual Disease (MRD) at the End of Induction (EOI) and Event Free Survival (EFS) in T-Cell Lymphoblastic Lymphoma (T-LL), a Report from the Children's Oncology Group (COG) Trial AALL1231. Blood. 2022 Nov 15; 140(Supplement 1):6387-6389. Hayashi HR, Hermiston HM, Teachey TD, Devidas DM, Wood WB, Chen CZ, Annett AR, Asselin AB, August AK, Cho CS, Dunsmore DK, Freedman FJ, Galardy GP, Harker-Murray HP, Horton HT, Jaju JA, Lam LA, Messinger MY, Miles MR, Okada OM, Patel PS, Schafer SE, Schechter-Finkelstein ST, Shimano SK, Singh SN, Steele SA, Sulis SM, Vargas VS, Winter WS, Wood WC, Zweidler-McKay ZP, Loh LM, Hunger HS, Raetz RE, Bollard BC, Allen AC. .
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    30. Clinical features associated with thrombotic events in children with myeloproliferative neoplasms. Am J Hematol. 2022 09; 97(9):E353-E355. Shimano KA, Vanderpoel V, Stone H, Resar L, Kucine N. PMID: 35751861; PMCID: PMC9378702.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Eczema and Petechiae in an Infant. Pediatr Rev. 2022 07 01; 43(7):e19-e23. Lloyd-McLennan AM, Shimano KA, Dorsey M, Cordoro KM. PMID: 35773537.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. How we approach the use of sirolimus and new agents: Medical therapy to treat vascular anomalies. Pediatr Blood Cancer. 2022 08; 69 Suppl 3:e29603. Shimano KA, Eng W, Adams DM. PMID: 35253343.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    33. A pilot trial of prophylactic defibrotide to prevent serious thrombotic microangiopathy in high-risk pediatric patients. Pediatr Blood Cancer. 2022 05; 69(5):e29641. Higham CS, Shimano KA, Melton A, Kharbanda S, Chu J, Dara J, Winestone LE, Hermiston ML, Huang JN, Dvorak CC. PMID: 35253361.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    34. Hematopoietic Cell Transplantation-Comorbidity Index Score Is Correlated with Treatment-Related Mortality and Overall Survival following Second Allogeneic Hematopoietic Cell Transplantation in Children. Transplant Cell Ther. 2022 03; 28(3):155.e1-155.e8. Forlanini F, Zinter MS, Dvorak CC, Bailey-Olson M, Winestone LE, Shimano KA, Higham CS, Melton A, Chu J, Kharbanda S. PMID: 34848362.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. An Unusual Presentation of Kaposiform Hemangioendothelioma in the Mandibular Bone. Blood. 2021 Nov 5; 138(Supplement 1):4205-4205. Rao RA, Ostedgaard OK, Zou ZY, Shimano SK. .
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    36. Angiographic Evidence of Response to Trametinib Therapy for a Spinal Cord Arteriovenous Malformation. . 2021 Sep 1; 2(3):e018. Cooke CD, Frieden FI, Shimano SK. .
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    37. Phase 3 randomised trial of eltrombopag versus standard first-line pharmacological management for newly diagnosed immune thrombocytopaenia (ITP) in children: study protocol. BMJ Open. 2021 08 27; 11(8):e044885. Shimano KA, Grace RF, Despotovic JM, Neufeld EJ, Klaassen RJ, Bennett CM, Ma C, London WB, Neunert C. PMID: 34452956; PMCID: PMC8404450.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    38. Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium. Am J Hematol. 2021 11 01; 96(11):1491-1504. Shimano KA, Narla A, Rose MJ, Gloude NJ, Allen SW, Bergstrom K, Broglie L, Carella BA, Castillo P, de Jong JLO, Dror Y, Geddis AE, Huang JN, Lau BW, McGuinn C, Nakano TA, Overholt K, Rothman JA, Sharathkumar A, Shereck E, Vlachos A, Olson TS, Bertuch AA, Wlodarski MW, Shimamura A, Boklan J. PMID: 34342889.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    39. Use of Complete Blood Cell Count Components to Screen for Hereditary Spherocytosis in Neonates. Pediatrics. 2021 09; 148(3). Weiss NM, Kuzniewicz MW, Shimano KA, Walsh EM, Newman TB. PMID: 34376530.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    40. Transplant-associated thrombotic microangiopathy in pediatric patients: pre-HSCT risk stratification and prophylaxis. Blood Adv. 2021 04 27; 5(8):2106-2114. Higham CS, Collins G, Shimano KA, Melton A, Kharbanda S, Winestone LE, Huang JN, Dara J, Long-Boyle JR, Dvorak CC. PMID: 33877298; PMCID: PMC8095147.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    41. Quality of life is an important indication for second-line treatment in children with immune thrombocytopenia. Pediatr Blood Cancer. 2021 06; 68(6):e29023. Shimano KA, Neunert C, Bussel JB, Klaassen RJ, Bhat R, Pastore YD, Lambert MP, Bennett CM, Despotovic JM, Forbes P, Grace RF. PMID: 33764667.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. A Pilot Trial of Pre-Transplant Risk Stratification and Prophylactic Defibrotide to Prevent Serious Thrombotic Microangiopathy in High-Risk Pediatric Hematopoietic Stem Cell Transplant Patients. Blood. 2020 Nov 5; 136(Supplement 1):9-10. Higham HC, Melton MA, Kharbanda KS, Dara DJ, Winestone WL, Huang HJ, Shimano SK. .
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    43. Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231. Blood. 2020 Nov 5; 136(Supplement 1):11-12. Teachey TD, Devidas DM, Wood WB, Chen CZ, Hayashi HR, Annett AR, Asselin AB, August AK, Cho CS, Dunsmore DK, Fisher FB, Freedman FJ, Galardy GP, Harker-Murray HP, Hermiston HM, Horton HT, Jaju JA, Lam LA, Messinger MY, Miles MR, Okada OM, Patel PS, Schafer SE, Schechter-Finkelstein ST, Shimano SK, Singh SN, Steele SA, Sulis SM, Vargas VS, Winter WS, Wood WC, McKay MP, Bollard BC, Loh LM, Hunger HS, Raetz RE. .
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    44. Monitoring Arteriovenous Malformation Response to Genotype-Targeted Therapy. Pediatrics. 2020 09; 146(3). Edwards EA, Phelps AS, Cooke D, Frieden IJ, Zapala MA, Fullerton HJ, Shimano KA. PMID: 32859736.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    45. Reduced Toxicity Conditioning for Nonmalignant Hematopoietic Cell Transplants. Biol Blood Marrow Transplant. 2020 09; 26(9):1646-1654. Contreras CF, Long-Boyle JR, Shimano KA, Melton A, Kharbanda S, Dara J, Higham C, Huang JN, Cowan MJ, Dvorak CC. PMID: 32534101.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    46. Fatigue in children and adolescents with immune thrombocytopenia. Br J Haematol. 2020 10; 191(1):98-106. Grace RF, Klaassen RJ, Shimano KA, Lambert MP, Grimes A, Bussel JB, Breakey VR, Pastore YD, Black V, Overholt K, Bhat R, Forbes PW, Neunert C. PMID: 32501532.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    47. The impact of total body irradiation-based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2020 02; 67(2):e28079. Friend BD, Bailey-Olson M, Melton A, Shimano KA, Kharbanda S, Higham C, Winestone LE, Huang J, Stieglitz E, Dvorak CC. PMID: 31724815.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    48. Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis. Blood. 2019 Nov 13; 134(Supplement_1):3343-3343. Dain DA, Hermiston HM, Shimano SK, Kharbanda KS, Melton MA, Dara DJ, Huang HJ, Dvorak DC. .
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    49. Reduced Toxicity Conditioning for Non-Malignant Hematopoietic Cell Transplants. Blood. 2019 Nov 13; 134(Supplement_1):4481-4481. Contreras CC, Long-Boyle LJ, Shimano SK, Dara DJ, Huang HJ, Kharbanda KS, Melton MA, Higham HC, Cowan CM, Dvorak DC. .
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    50. A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children. Blood. 2019 Nov 13; 134(Supplement_1):2369-2369. Shimano SK, Grace GR, Bennett BC, Klaassen KR, Neunert NC, Neufeld NE, Ma MC, London LW, Despotovic DJ. .
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    51. Autoimmune Cytopenias in Pediatric Hematopoietic Cell Transplant Patients. Front Pediatr. 2019; 7:171. Neely JA, Dvorak CC, Pantell MS, Melton A, Huang JN, Shimano KA. PMID: 31131266; PMCID: PMC6509944.
      View in: PubMed   Mentions: 11  
    52. Second-line treatments in children with immune thrombocytopenia: Effect on platelet count and patient-centered outcomes. Am J Hematol. 2019 07; 94(7):741-750. Grace RF, Shimano KA, Bhat R, Neunert C, Bussel JB, Klaassen RJ, Lambert MP, Rothman JA, Breakey VR, Hege K, Bennett CM, Rose MJ, Haley KM, Buchanan GR, Geddis A, Lorenzana A, Jeng M, Pastore YD, Crary SE, Neier M, Neufeld EJ, Neu N, Forbes PW, Despotovic JM. PMID: 30945320; PMCID: PMC6527349.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    53. Transplant-Associated Thrombotic Microangiopathy in Pediatric Hematopoietic Cell Transplant Recipients: A Practical Approach to Diagnosis and Management. Front Pediatr. 2019; 7:133. Dvorak CC, Higham C, Shimano KA. PMID: 31024873; PMCID: PMC6465621.
      View in: PubMed   Mentions: 48  
    54. Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency. Biol Blood Marrow Transplant. 2019 07; 25(7):1355-1362. Dvorak CC, Long-Boyle J, Dara J, Melton A, Shimano KA, Huang JN, Puck JM, Dorsey MJ, Facchino J, Chang CK, Cowan MJ. PMID: 30876930; PMCID: PMC7384257.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsCTClinical Trials
    55. The Impact of Total Body Irradiation-Based Regimens on Outcomes in Children and Young Adults with Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation. 2019 Mar 1; 25(3):s197-s198. Friend FB, Bailey-Olson BM, Higham HC, Dara DJ, Melton MA, Shimano SK, Huang HJ, Kharbanda KS, Dvorak DC. .
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    56. Anemia and Neutropenia. . 2019 Jan 1; 443-448. Shimano SK. .
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    57. Daratumumab in life-threatening autoimmune hemolytic anemia following hematopoietic stem cell transplantation. Blood Adv. 2018 10 09; 2(19):2550-2553. Schuetz C, Hoenig M, Moshous D, Weinstock C, Castelle M, Bendavid M, Shimano K, Tolbert V, Schulz AS, Dvorak CC. PMID: 30291113; PMCID: PMC6177653.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    58. Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. Am J Hematol. 2018 07; 93(7):882-888. Grace RF, Despotovic JM, Bennett CM, Bussel JB, Neier M, Neunert C, Crary SE, Pastore YD, Klaassen RJ, Rothman JA, Hege K, Breakey VR, Rose MJ, Shimano KA, Buchanan GR, Geddis A, Haley KM, Lorenzana A, Thompson A, Jeng M, Neufeld EJ, Brown T, Forbes PW, Lambert MP. PMID: 29659042; PMCID: PMC6037544.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    59. Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children. bioRxiv. 2018 Mar 29; 291864. Zinter ZM, Dvorak DC, Mayday MM, Iwanaga IK, Ly LN, McGarry MM, Church CG, Faricy FL, Rowan RC, Hume HJ, Steiner SM, Crawford CE, Langelier LC, Kalantar KK, Chow CE, Miller MS, Shimano SK, Melton MA, Yanik YG, Sapru SA, DeRisi DJ. .
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    60. Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP). Blood. 2017 Dec 7; 130(Suppl_1):752-752. Grace GR, Klaassen KR, Bhat BR, Neier NM, Rose RM, Despotovic DJ, Bennett BC, Bussel BJ, Rothman RJ, Breakey BV, Hege HK, Shimano SK, Haley HK, Geddis GA, Buchanan BG, Lorenzano LA, Neunert NC, Jeng JM, Pastore PY, Crary CS, Neufeld NE, Neu NN, Forbes FP, Lambert LM. .
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    61. Sirolimus for management of complex vascular anomalies - A proposed dosing regimen for very young infants. Int J Pediatr Otorhinolaryngol. 2018 Feb; 105:48-51. Czechowicz JA, Long-Boyle JR, Rosbe KW, Mathes EF, Frieden IJ, Shimano KA. PMID: 29447818.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    62. JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias. Leukemia. 2017 12; 31(12):2568-2576. Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML. PMID: 28484265; PMCID: PMC5729333.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    63. Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP. Blood. 2016 Dec 2; 128(22):1008-1008. Lambert LM, Grace GR, Neunert NC, Despotovic DJ, Bhat BR, Pastore PY, Buchanan BG, Klaassen KR, Bennett BC, Rothman RJ, Breakey BV, Bussel BJ, Rose RM, Geddis GA, Shimano SK, Hege HK, Haley HK, Lorenzana LA, Jeng JM, Crary CS, Neier NM, Brown BT, Forbes FP, Neufeld NE. .
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    64. Clinical Characteristics and Quality of Life of Children with ITP Starting Second Line Treatments: Data from the ITP Consortium of North America ICON1 Study. Blood. 2016 Dec 2; 128(22):249-249. Grace GR, Klaassen KR, Rothman RJ, Hege HK, Neufeld NE, Bennett BC, Lambert LM, Breakey BV, Bussel BJ, Buchanan BG, Rose RM, Geddis GA, Shimano SK, Haley HK, Lorenzana LA, Neunert NC, Thompson TA, Pastore PY, Jeng JM, Crary CS, Neier NM, Brown BT, Forbes FP, Despotovic DJ. .
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    65. Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study. Blood. 2016 Dec 2; 128(22):4752-4752. Vicky VB, Grace GR, Bennett BC, Despotovic DJ, Rothman RJ, Pastore PY, Neufeld NE, Klaassen KR, Lambert LM, Bussel BJ, Buchanan BG, Rose RM, Geddis GA, Shimano SK, Hege HK, Haley HK, Lorenzana LA, Thompson TA, Jeng JM, Crary CS, Neier NM, Brown BT, Forbes FP, Neunert NC. .
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    66. JAK/STAT Pathway Inhibition Reverts IL7-Induced Glucocorticoid Resistance in a Subset of Human T-Cell Acute Lymphoblastic Leukemia. Blood. 2016 Dec 2; 128(22):3963-3963. Delgado-Martin DC, Shimano SK, Zinter ZM, Wahlstrom WJ, Smith SG, Taunton TJ, Winter WS, Roderick RJ, Kelliher KM, Horton HT, Wood WB, Teachey TD, Hermiston HM. .
      View in: Publisher Site   Mentions:
    67. Daratumumab Is Effective in the Treatment of Refractory Post-Transplant Autoimmune Hemolytic Anemia: A Pediatric Case Report. Blood. 2016 Dec 2; 128(22):4819-4819. Tolbert TV, Goldsby GR, Huang HJ, Shimano SK, Melton MA, Willert WJ, Horn HB, Dvorak DC, Wahlstrom WJ. .
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    68. Thrombopoietin Receptor Agonist Use in Children: Data From the Pediatric ITP Consortium of North America ICON2 Study. Pediatr Blood Cancer. 2016 08; 63(8):1407-13. Neunert C, Despotovic J, Haley K, Lambert MP, Nottage K, Shimano K, Bennett C, Klaassen R, Stine K, Thompson A, Pastore Y, Brown T, Forbes PW, Grace RF, Pediatric ITP Consortium of North America (ICON). PMID: 27135461; PMCID: PMC5718620.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    69. Autoimmune Cytopenias in Pediatric Hematopoietic Cell Transplant (HCT) Patients. Biology of Blood and Marrow Transplantation. 2016 Mar 1; 22(3):s255. Neely NJ, Dvorak DC, Pantell PM, Shimano SK. .
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    70. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 2012 Jan 11; 481(7380):157-63. Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG. PMID: 22237106; PMCID: PMC3267575.
      View in: PubMed   Mentions: 886     Fields:    Translation:HumansCells
    71. Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project. Blood. 2011 Nov 18; 118(21):68-68. Zhang ZJ, Ding DL, Holmfeldt HL, Wu WG, Heatley HS, Payne-Turner PD, Easton EJ, Chen CX, Wang WJ, Rusch RM, Lu LC, Chen CS, Collins-Underwood CR, Ma MJ, Roberts RK, Pounds PS, Wei WL, Ulyanov UA, Becksfort BJ, Gupta GP, Huether HR, Kriwacki KR, McGoldrick MD, Zhao ZD, Alford AD, Espy ES, Bobba BK, Song SG, Pei PD, Cheng CC, Roberts RS, Barbato BM, Campana CD, Coustan-Smith CE, Evans EW, Shurtleff SS, Kleppe KM, Cools CJ, Shimano SK, Hermiston HM, Doulatov DS, Eppert EK, Laurenti LE, Notta NF, Dick DJ, Basso BG, Hunger HS, Loh LM, Devidas DM, Wood WB, Winter WS, Dunsmore DK, Fulton FR, Fulton FL, Hong HX, Harris HC, Dooling DD, Ochoa OK, Johnson JK, Obenauer OJ, Pui PC, Raimondi RS, Naeve NC, Ley LT, Mardis ME, Wilson WR, Downing DJ, Mullighan MC. .
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    72. Immunosuppressive activity of FTY720, sphingosine 1-phosphate receptor agonist: II. Effect of FTY720 and FTY720-phosphate on host-versus-graft and graft-versus-host reaction in mice. Transplant Proc. 2005 Jan-Feb; 37(1):107-9. Kataoka H, Ohtsuki M, Shimano K, Mochizuki S, Oshita K, Murata M, Sugahara K, Sato N, Hoshino Y, Chiba K. PMID: 15808562.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
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