-
Poor melanoma outcomes and survival in Asian American and Pacific Islander patients. J Am Acad Dermatol. 2021 Jun; 84(6):1725-1727.
Zheng YJ, Ho C, Lazar A, Ortiz-Urda S. PMID: 32860918.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
A dual pathway inhibition strategy using BKM120 combined with vemurafenib is poorly tolerated in BRAF V600E/K mutant advanced melanoma. Pigment Cell Melanoma Res. 2019 07; 32(4):603-606.
Algazi AP, Rotow J, Posch C, Ortiz-Urda S, Pelayo A, Munster PN, Daud A. PMID: 30801911.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
MEK/CDK4,6 co-targeting is effective in a subset of NRAS, BRAF and 'wild type' melanomas. Oncotarget. 2018 Oct 09; 9(79):34990-34995.
Posch C, Sanlorenzo M, Ma J, Kim ST, Zekhtser M, Ortiz-Urda S. PMID: 30405888; PMCID: PMC6201855.
View in:
PubMed Mentions:
7 Fields:
-
The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma. Sci Rep. 2018 Jul 19; 8(1):10902.
Sanlorenzo M, Vujic I, Esteve-Puig R, Lai K, Vujic M, Lin K, Posch C, Dimon M, Moy A, Zekhtser M, Johnston K, Gho D, Ho W, Gajjala A, Oses Prieto J, Burlingame A, Daud A, Rappersberger K, Ortiz-Urda S. PMID: 30026510; PMCID: PMC6053443.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Cutaneous CD56+ T-cell lymphoma developing during pembrolizumab treatment for metastatic melanoma. JAAD Case Rep. 2018 Jul; 4(6):540-542.
Zheng YJ, Lee A, Pincus L, Ho W, Vujic M, Ortiz-Urda S. PMID: 29892669; PMCID: PMC5991899.
View in:
PubMed Mentions:
10
-
Dual MEK/AKT inhibition with trametinib and GSK2141795 does not yield clinical benefit in metastatic NRAS-mutant and wild-type melanoma. Pigment Cell Melanoma Res. 2018 01; 31(1):110-114.
Algazi AP, Esteve-Puig R, Nosrati A, Hinds B, Hobbs-Muthukumar A, Nandoskar P, Ortiz-Urda S, Chapman PB, Daud A. PMID: 28921907; PMCID: PMC8049535.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCTClinical Trials
-
New insights in melanoma biomarkers: long-noncoding RNAs. Melanoma Manag. 2016 Sep; 3(3):195-205.
Moreno-Traspas R, Vujic I, Sanlorenzo M, Ortiz-Urda S. PMID: 30190889; PMCID: PMC6094599.
View in:
PubMed Mentions:
-
Pharmacological inhibitors of c-KIT block mutant c-KIT mediated migration of melanocytes and melanoma cells in vitro and in vivo. Oncotarget. 2016 Jul 19; 7(29):45916-45925.
Posch C, Moslehi H, Sanlorenzo M, Green G, Vujic I, Panzer-Grümayer R, Rappersberger K, Ortiz-Urda S. PMID: 27322141; PMCID: PMC5216770.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Phosphoproteomic Analyses of NRAS(G12) and NRAS(Q61) Mutant Melanocytes Reveal Increased CK2α Kinase Levels in NRAS(Q61) Mutant Cells. J Invest Dermatol. 2016 10; 136(10):2041-2048.
Posch C, Sanlorenzo M, Vujic I, Oses-Prieto JA, Cholewa BD, Kim ST, Ma J, Lai K, Zekhtser M, Esteve-Puig R, Green G, Chand S, Burlingame AL, Panzer-Grümayer R, Rappersberger K, Ortiz-Urda S. PMID: 27251789; PMCID: PMC6373467.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Oncogenic KIT mutations in different exons lead to specific changes in melanocyte phospho-proteome. J Proteomics. 2016 07 20; 144:140-7.
Sanlorenzo M, Vujic I, Posch C, Ma J, Lin K, Lai K, Lee D, Vujic M, Oses-Prieto JA, Chand S, Rodriguez-Peralto JL, Burlingame A, Ortiz-Urda S. PMID: 27216642; PMCID: PMC5026456.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Searching for the Chokehold of NRAS Mutant Melanoma. J Invest Dermatol. 2016 07; 136(7):1330-1336.
Posch C, Vujic I, Monshi B, Sanlorenzo M, Weihsengruber F, Rappersberger K, Ortiz-Urda S. PMID: 27160069; PMCID: PMC4921268.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells. Oncotarget. 2016 Feb 09; 7(6):7297-306.
Vujic I, Sanlorenzo M, Esteve-Puig R, Vujic M, Kwong A, Tsumura A, Murphy R, Moy A, Posch C, Monshi B, Rappersberger K, Ortiz-Urda S. PMID: 26771141; PMCID: PMC4872786.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
The burden of malignant melanoma--lessons to be learned from Austria. Eur J Cancer. 2016 Mar; 56:45-53.
Monshi B, Vujic M, Kivaranovic D, Sesti A, Oberaigner W, Vujic I, Ortiz-Urda S, Posch C, Feichtinger H, Hackl M, Rappersberger K. PMID: 26802530.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Time-Dependent Measurement of Adverse Events-Reply. JAMA Dermatol. 2015 Dec 01; 151(12):1392-1393.
Sanlorenzo M, Vujic I, Ortiz-Urda S. PMID: 26650664; PMCID: PMC11037295.
View in:
PubMed Mentions: Fields:
-
Pembrolizumab Cutaneous Adverse Events and Their Association With Disease Progression. JAMA Dermatol. 2015 Nov; 151(11):1206-1212.
Sanlorenzo M, Vujic I, Daud A, Algazi A, Gubens M, Luna SA, Lin K, Quaglino P, Rappersberger K, Ortiz-Urda S. PMID: 26222619; PMCID: PMC5061067.
View in:
PubMed Mentions:
188 Fields:
Translation:
Humans
-
Melanoma risk perception and prevention behavior among African-Americans: the minority melanoma paradox. Clin Cosmet Investig Dermatol. 2015; 8:423-9.
Goldenberg A, Vujic I, Sanlorenzo M, Ortiz-Urda S. PMID: 26346576; PMCID: PMC4531028.
View in:
PubMed Mentions:
5
-
Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma. J Invest Dermatol. 2015 Oct; 135(10):2475-2483.
Posch C, Cholewa BD, Vujic I, Sanlorenzo M, Ma J, Kim ST, Kleffel S, Schatton T, Rappersberger K, Gutteridge R, Ahmad N, Ortiz/Urda S. PMID: 26016894; PMCID: PMC4567913.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
-
Correction: Cost-Effectiveness Of Treatment Strategies for BRAF-Mutated Metastatic Melanoma. PLoS One. 2015; 10(4):e0126988.
Curl P, Vujic I, van 't Veer LJ, Ortiz-Urda S, Kahn JG. PMID: 25893993; PMCID: PMC4404367.
View in:
PubMed Mentions: Fields:
-
The risk of melanoma in pilots and cabin crew: UV measurements in flying airplanes. JAMA Dermatol. 2015 Apr; 151(4):450-2.
Sanlorenzo M, Vujic I, Posch C, Cleaver JE, Quaglino P, Ortiz-Urda S. PMID: 25517516; PMCID: PMC4476387.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansPHPublic Health
-
The combination of axitinib followed by paclitaxel/carboplatin yields extended survival in advanced BRAF wild-type melanoma: results of a clinical/correlative prospective phase II clinical trial. Br J Cancer. 2015 Apr 14; 112(8):1326-31.
Algazi AP, Cha E, Ortiz-Urda SM, McCalmont T, Bastian BC, Hwang J, Pampaloni MH, Behr S, Chong K, Cortez B, Quiroz A, Coakley F, Liu S, Daud AI. PMID: 25867272; PMCID: PMC4402449.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCTClinical Trials
-
Detection of GNAQ mutations and reduction of cell viability in uveal melanoma cells with functionalized gold nanoparticles. Biomed Microdevices. 2015 Feb; 17(1):15.
Posch C, Latorre A, Crosby MB, Celli A, Latorre A, Vujic I, Sanlorenzo M, Green GA, Weier J, Zekhtser M, Ma J, Monico G, Char DH, Jusufbegovic D, Rappersberger K, Somoza Á, Ortiz-Urda S. PMID: 25653058; PMCID: PMC4586106.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer. Oncotarget. 2015 Jan 20; 6(2):969-78.
Vujic I, Sanlorenzo M, Posch C, Esteve-Puig R, Yen AJ, Kwong A, Tsumura A, Murphy R, Rappersberger K, Ortiz-Urda S. PMID: 25504439; PMCID: PMC4359268.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
-
The risk of melanoma in airline pilots and cabin crew: a meta-analysis. JAMA Dermatol. 2015 Jan; 151(1):51-8.
Sanlorenzo M, Wehner MR, Linos E, Kornak J, Kainz W, Posch C, Vujic I, Johnston K, Gho D, Monico G, McGrath JT, Osella-Abate S, Quaglino P, Cleaver JE, Ortiz-Urda S. PMID: 25188246; PMCID: PMC4482339.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansPHPublic Health
-
Comparative profile of cutaneous adverse events: BRAF/MEK inhibitor combination therapy versus BRAF monotherapy in melanoma. J Am Acad Dermatol. 2014 Dec; 71(6):1102-1109.e1.
Sanlorenzo M, Choudhry A, Vujic I, Posch C, Chong K, Johnston K, Meier M, Osella-Abate S, Quaglino P, Daud A, Algazi A, Rappersberger K, Ortiz-Urda S. PMID: 25440439; PMCID: PMC4254519.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Mutant NRASQ61 shares signaling similarities across various cancer types--potential implications for future therapies. Oncotarget. 2014 Sep 15; 5(17):7936-44.
Vujic I, Posch C, Sanlorenzo M, Yen AJ, Tsumura A, Kwong A, Feichtenschlager V, Lai K, Arneson DV, Rappersberger K, Ortiz-Urda SM. PMID: 25277205; PMCID: PMC4202171.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Cost-effectiveness of treatment strategies for BRAF-mutated metastatic melanoma. PLoS One. 2014; 9(9):e107255.
Curl P, Vujic I, van 't Veer LJ, Ortiz-Urda S, Kahn JG. PMID: 25198196; PMCID: PMC4157865.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Merkel cell carcinoma: mitoses, expression of Ki-67 and bcl-2 correlate with disease progression. J Eur Acad Dermatol Venereol. 2015 Mar; 29(3):542-8.
Vujic I, Marker M, Posch C, Mühlehner D, Monshi B, Breier F, Steiner A, Ortiz-Urda S, Rappersberger K. PMID: 25088273.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
DNA and aptamer stabilized gold nanoparticles for targeted delivery of anticancer therapeutics. Nanoscale. 2014 Jul 07; 6(13):7436-42.
Latorre A, Posch C, Garcimartín Y, Celli A, Sanlorenzo M, Vujic I, Ma J, Zekhtser M, Rappersberger K, Ortiz-Urda S, Somoza Á. PMID: 24882040.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Single-point mutation detection in RNA extracts using gold nanoparticles modified with hydrophobic molecular beacon-like structures. Chem Commun (Camb). 2014 Mar 21; 50(23):3018-20.
Latorre A, Posch C, Garcimartín Y, Ortiz-Urda S, Somoza Á. PMID: 24496380; PMCID: PMC4339280.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Melanoma immunotherapy. Cancer Biol Ther. 2014 Jun 01; 15(6):665-74.
Sanlorenzo M, Vujic I, Posch C, Dajee A, Yen A, Kim S, Ashworth M, Rosenblum MD, Algazi A, Osella-Abate S, Quaglino P, Daud A, Ortiz-Urda S. PMID: 24651672; PMCID: PMC4049781.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
-
Mycoplasma pneumoniae-associated mucositis--case report and systematic review of literature. J Eur Acad Dermatol Venereol. 2015 Mar; 29(3):595-8.
Vujic I, Shroff A, Grzelka M, Posch C, Monshi B, Sanlorenzo M, Ortiz-Urda S, Rappersberger K. PMID: 24665876.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Low-dose inhalation of interleukin-2 bio-chemotherapy for the treatment of pulmonary metastases in melanoma patients. Br J Cancer. 2014 Mar 18; 110(6):1427-32.
Posch C, Weihsengruber F, Bartsch K, Feichtenschlager V, Sanlorenzo M, Vujic I, Monshi B, Ortiz-Urda S, Rappersberger K. PMID: 24518593; PMCID: PMC3960625.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
NRAS mutant melanoma--undrugable? Oncotarget. 2013 Apr; 4(4):494-5.
Posch C, Ortiz-Urda S. PMID: 23660168; PMCID: PMC3720596.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo. Proc Natl Acad Sci U S A. 2013 Mar 05; 110(10):4015-20.
Posch C, Moslehi H, Feeney L, Green GA, Ebaee A, Feichtenschlager V, Chong K, Peng L, Dimon MT, Phillips T, Daud AI, McCalmont TH, LeBoit PE, Ortiz-Urda S. PMID: 23431193; PMCID: PMC3593920.
View in:
PubMed Mentions:
125 Fields:
Translation:
HumansAnimalsCells
-
Cutting edge in medical management of cutaneous oncology. Semin Cutan Med Surg. 2012 Jun; 31(2):140-9.
Chong K, Daud A, Ortiz-Urda S, Arron ST, UCSF High Risk Skin Cancer Program. PMID: 22640435; PMCID: PMC3367308.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression. Cancer Cell. 2009 Jun 02; 15(6):477-88.
Reuter JA, Ortiz-Urda S, Kretz M, Garcia J, Scholl FA, Pasmooij AM, Cassarino D, Chang HY, Khavari PA. PMID: 19477427; PMCID: PMC3050547.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
-
A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation. Cancer Res. 2007 May 01; 67(9):4264-70.
Waterman EA, Sakai N, Nguyen NT, Horst BA, Veitch DP, Dey CN, Ortiz-Urda S, Khavari PA, Marinkovich MP. PMID: 17483338.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
-
Type VII collagen is required for Ras-driven human epidermal tumorigenesis. Science. 2005 Mar 18; 307(5716):1773-6.
Ortiz-Urda S, Garcia J, Green CL, Chen L, Lin Q, Veitch DP, Sakai LY, Lee H, Marinkovich MP, Khavari PA. PMID: 15774758.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
-
[Erythema induratum-nodular vasculitis]. J Dtsch Dermatol Ges. 2004 Mar; 2(3):206-14; quiz 215.
Marker M, Ortiz-Urda S, Lilgenau N, Rappersberger K. PMID: 16281639.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Carbamazepine-induced DRESS syndrome with recurrent fever and exanthema. Int J Dermatol. 2004 Jan; 43(1):51-4.
Valencak J, Ortiz-Urda S, Heere-Ress E, Kunstfeld R, Base W. PMID: 14693022.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
The plant lectin wheat germ agglutinin inhibits the binding of pemphigus foliaceus autoantibodies to desmoglein 1 in a majority of patients and prevents pathomechanisms of pemphigus foliaceus in vitro and in vivo. J Immunol. 2003 Dec 01; 171(11):6244-50.
Ortiz-Urda S, Elbe-Bürger A, Smolle J, Marquart Y, Chudnovsky Y, Ridky TW, Bernstein P, Wolff K, Rappersberger K. PMID: 14634141.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer. Gene Ther. 2003 Jul; 10(13):1099-104.
Ortiz-Urda S, Lin Q, Yant SR, Keene D, Kay MA, Khavari PA. PMID: 12808440.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
PhiC31 integrase-mediated nonviral genetic correction of junctional epidermolysis bullosa. Hum Gene Ther. 2003 Jun 10; 14(9):923-8.
Ortiz-Urda S, Thyagarajan B, Keene DR, Lin Q, Calos MP, Khavari PA. PMID: 12828862.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
-
[New immunosuppressive agents for treating psoriasis]. Hautarzt. 2003 Mar; 54(3):230-6.
Ortiz-Urda S, Rappersberger K. PMID: 12634991.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue. J Clin Invest. 2003 Jan; 111(2):251-5.
Ortiz-Urda S, Lin Q, Green CL, Keene DR, Marinkovich MP, Khavari PA. PMID: 12531881; PMCID: PMC151880.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
-
Stable nonviral genetic correction of inherited human skin disease. Nat Med. 2002 Oct; 8(10):1166-70.
Ortiz-Urda S, Thyagarajan B, Keene DR, Lin Q, Fang M, Calos MP, Khavari PA. PMID: 12244305.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
-
Pathogenesis of the permeability barrier abnormality in epidermolytic hyperkeratosis. J Invest Dermatol. 2001 Oct; 117(4):837-47.
Schmuth M, Yosipovitch G, Williams ML, Weber F, Hintner H, Ortiz-Urda S, Rappersberger K, Crumrine D, Feingold KR, Elias PM. PMID: 11676820.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
A localized variant of paraneoplastic pemphigus: acantholysis associated with malignant melanoma. Br J Dermatol. 2001 Jun; 144(6):1249-54.
Schaeppi H, Bauer JW, Hametner R, Metze D, Ortiz-Urda S, Salmhofer W, Rappersberger K, Hintner H. PMID: 11422052.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans