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    Licia Selleri, PhD, MD

    TitleProfessor
    SchoolUCSF School of Dentistry
    DepartmentOrofacial Sciences
    Address513 Parnassus Ave
    San Francisco CA 94143
    Phone415-502-2263
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      Collapse Biography 
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      Ginnasio Ludovico MuratoriBaccalaureat1980
      University of ModenaM.D. Medical School1985
      University of Modena, and Erasmus University (Advisors: Dr. Umberto Torelli & Dr. Gerard Grosveld)Ph.D. Molecular BiologyGraduate School1990
      The Salk Institute for Biological Studies, Molecular Genetics Laboratory (Advisor: Dr. Glen Evans)“Fogarty” Postdoctoral Fellow1992

      Collapse Overview 
      Collapse Overview
      UCSF School of Medicine
      Department of Anatomy
      Institute of Human Genetics
      Eli and Edythe Broad Center of Regeneration Medicine & Stem Cell Research

      Genetic and regulatory control of morphogenesis in embryonic development, evolution, and disease

      The laboratory studies the genetic and regulatory basis of how elaborately patterned tissues form during embryonic development and evolution. The laboratory combines different genetic approaches, using the mouse as a model, to understand the mechanisms underpinning basic developmental processes related to cranial and appendicular morphogenesis. They discovered that homeodomain-containing transcription factors of the Pbx family, also known as Hox-cofactors, are critical developmental regulators through the transcriptional control of target genes within tissue-specific regulatory networks. The lab uses genetically-engineered and ethylnitrosourea (ENU)-mutagenized mouse lines. Recently they utilize additional animal models, such as jerboas and primates, with the ultimate goal to identify novel genes and regulatory networks underlying morphogenesis of embryonic structures, morphological variation, and evolution. Focus is also given to how perturbation of these regulatory networks can result in human congenital disease.


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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Jung JG, Shih IM, Park JT, Gerry E, Kim TH, Ayhan A, Handschuh K, Davidson B, Nickles Fader A, Selleri L, Wang TL. Ovarian cancer chemoresistance relies on the the stem cell reprogramming factor PBX1. Cancer Res. 2016 Sep 2. PMID: 27590741.
        View in: PubMed
      2. Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee DH, Selleri L, Dasen JS. Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron. 2016 Sep 7; 91(5):1005-20. PMID: 27568519; PMCID: PMC5017921 [Available on 09/07/17].
      3. Villaescusa JC, Li B, Toledo EM, Rivetti di Val Cervo P, Yang S, Stott SR, Kaiser K, Islam S, Gyllborg D, Laguna-Goya R, Landreh M, Lönnerberg P, Falk A, Bergman T, Barker RA, Linnarsson S, Selleri L, Arenas E, et al. A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease. EMBO J. 2016 Jun 28. PMID: 27354364.
        View in: PubMed
      4. Brinkley JF, Fisher S, Harris MP, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Maas RL, Marazita ML, Selleri L, Spritz RA, van Bakel H, Visel A, Williams TJ, Wysocka J, Chai Y, et al. The FaceBase Consortium: a comprehensive resource for craniofacial researchers. Development. 2016 Jul 15; 143(14):2677-88. PMID: 27287806.
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      5. Grebbin BM, Hau AC, Groß A, Anders-Maurer M, Schramm J, Koss M, Wille C, Mittelbronn M, Selleri L, Schulte D, et al. Pbx1 is required for adult subventricular zone neurogenesis. Development. 2016 Jul 1; 143(13):2281-91. PMID: 27226325.
        View in: PubMed
      6. Zewdu R, Risolino M, Barbulescu A, Ramalingam P, Butler JM, Selleri L. Spleen hypoplasia leads to abnormal stress hematopoiesis in mice with loss of Pbx homeoproteins in splenic mesenchyme. J Anat. 2016 Jul; 229(1):153-69. PMID: 27075259.
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      7. Golonzhka O, Nord A, Tang PL, Lindtner S, Ypsilanti AR, Ferretti E, Visel A, Selleri L, Rubenstein JL. Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons. Neuron. 2015 Dec 16; 88(6):1192-207. PMID: 26671461.
        View in: PubMed
      8. Prescott SL, Srinivasan R, Marchetto MC, Grishina I, Narvaiza I, Selleri L, Gage FH, Swigut T, Wysocka J. Enhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural Crest. Cell. 2015 Sep 24; 163(1):68-83. PMID: 26365491.
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      9. Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D. Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 1; 142(15):2653-64. PMID: 26138478; PMCID: PMC4529034 [Available on 08/01/16].
      10. Han YC, Vidigal JA, Mu P, Yao E, Singh I, González AJ, Concepcion CP, Bonetti C, Ogrodowski P, Carver B, Selleri L, Betel D, Leslie C, Ventura A. An allelic series of miR-17 ~ 92-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron. Nat Genet. 2015 Jul; 47(7):766-75. PMID: 26029871; PMCID: PMC4485521 [Available on 01/01/16].
      11. Vierstra J, Rynes E, Sandstrom R, Zhang M, Canfield T, Hansen RS, Stehling-Sun S, Sabo PJ, Byron R, Humbert R, Thurman RE, Johnson AK, Vong S, Lee K, Bates D, Neri F, Diegel M, Giste E, Haugen E, Dunn D, Wilken MS, Josefowicz S, Samstein R, Chang KH, Eichler EE, De Bruijn M, Reh TA, Skoultchi A, Rudensky A, Orkin SH, Papayannopoulou T, Treuting PM, Selleri L, Kaul R, Groudine M, Bender MA, Stamatoyannopoulos JA. Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution. Science. 2014 Nov 21; 346(6212):1007-12. PMID: 25411453; PMCID: PMC4337786 [Available on 11/21/15].
      12. Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, Rynes E, Kirilusha A, Marinov GK, Williams BA, Trout D, Amrhein H, Fisher-Aylor K, Antoshechkin I, DeSalvo G, See LH, Fastuca M, Drenkow J, Zaleski C, Dobin A, Prieto P, Lagarde J, Bussotti G, Tanzer A, Denas O, Li K, Bender MA, Zhang M, Byron R, Groudine MT, McCleary D, Pham L, Ye Z, Kuan S, Edsall L, Wu YC, Rasmussen MD, Bansal MS, Kellis M, Keller CA, Morrissey CS, Mishra T, Jain D, Dogan N, Harris RS, Cayting P, Kawli T, Boyle AP, Euskirchen G, Kundaje A, Lin S, Lin Y, Jansen C, Malladi VS, Cline MS, Erickson DT, Kirkup VM, Learned K, Sloan CA, Rosenbloom KR, Lacerda de Sousa B, Beal K, Pignatelli M, Flicek P, Lian J, Kahveci T, Lee D, Kent WJ, Ramalho Santos M, Herrero J, Notredame C, Johnson A, Vong S, Lee K, Bates D, Neri F, Diegel M, Canfield T, Sabo PJ, Wilken MS, Reh TA, Giste E, Shafer A, Kutyavin T, Haugen E, Dunn D, Reynolds AP, Neph S, Humbert R, Hansen RS, De Bruijn M, Selleri L, Rudensky A, Josefowicz S, Samstein R, Eichler EE, Orkin SH, Levasseur D, Papayannopoulou T, Chang KH, Skoultchi A, Gosh S, Disteche C, Treuting P, Wang Y, Weiss MJ, Blobel GA, Cao X, Zhong S, Wang T, Good PJ, Lowdon RF, Adams LB, Zhou XQ, Pazin MJ, Feingold EA, Wold B, Taylor J, Mortazavi A, Weissman SM, Stamatoyannopoulos JA, Snyder MP, Guigo R, Gingeras TR, Gilbert DM, Hardison RC, Beer MA, Ren B. A comparative encyclopedia of DNA elements in the mouse genome. Nature. 2014 Nov 20; 515(7527):355-64. PMID: 25409824; PMCID: PMC4266106.
      13. Cheng Y, Ma Z, Kim BH, Wu W, Cayting P, Boyle AP, Sundaram V, Xing X, Dogan N, Li J, Euskirchen G, Lin S, Lin Y, Visel A, Kawli T, Yang X, Patacsil D, Keller CA, Giardine B, Kundaje A, Wang T, Pennacchio LA, Weng Z, Hardison RC, Snyder MP. Principles of regulatory information conservation between mouse and human. Nature. 2014 Nov 20; 515(7527):371-5. PMID: 25409826; PMCID: PMC4343047.
      14. Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP. Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May; 52(5):399-407. PMID: 24591256.
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      15. Hall KC, Hill D, Otero M, Plumb DA, Froemel D, Dragomir CL, Maretzky T, Boskey A, Crawford HC, Selleri L, Goldring MB, Blobel CP. ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes. Mol Cell Biol. 2013 Aug; 33(16):3077-90. PMID: 23732913; PMCID: PMC3753912.
      16. Bolze A, Mahlaoui N, Byun M, Turner B, Trede N, Ellis SR, Abhyankar A, Itan Y, Patin E, Brebner S, Sackstein P, Puel A, Picard C, Abel L, Quintana-Murci L, Faust SN, Williams AP, Baretto R, Duddridge M, Kini U, Pollard AJ, Gaud C, Frange P, Orbach D, Emile JF, Stephan JL, Sorensen R, Plebani A, Hammarstrom L, Conley ME, Selleri L, Casanova JL. Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia. Science. 2013 May 24; 340(6135):976-8. PMID: 23579497; PMCID: PMC3677541.
      17. Feldhahn N, Ferretti E, Robbiani DF, Callen E, Deroubaix S, Selleri L, Nussenzweig A, Nussenzweig MC. The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. EMBO J. 2012 Oct 17; 31(20):4045-56. PMID: 22940690; PMCID: PMC3474923.
      18. Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L. Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module. Dev Cell. 2012 May 15; 22(5):913-26. PMID: 22560297; PMCID: PMC3356505.
      19. Ferretti E, Li B, Zewdu R, Wells V, Hebert JM, Karner C, Anderson MJ, Williams T, Dixon J, Dixon MJ, Depew MJ, Selleri L. A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis. Dev Cell. 2011 Oct 18; 21(4):627-41. PMID: 21982646; PMCID: PMC3199312.
      20. Gordon JA, Hassan MQ, Koss M, Montecino M, Selleri L, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex. Cells Tissues Organs. 2011; 194(2-4):146-50. PMID: 21597276; PMCID: PMC3178072.
      21. Vitobello A, Ferretti E, Lampe X, Vilain N, Ducret S, Ori M, Spetz JF, Selleri L, Rijli FM. Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation. Dev Cell. 2011 Apr 19; 20(4):469-82. PMID: 21497760; PMCID: PMC3677862.
      22. Capellini TD, Handschuh K, Quintana L, Ferretti E, Di Giacomo G, Fantini S, Vaccari G, Clarke SL, Wenger AM, Bejerano G, Sharpe J, Zappavigna V, Selleri L. Control of pelvic girdle development by genes of the Pbx family and Emx2. Dev Dyn. 2011 May; 240(5):1173-89. PMID: 21455939; PMCID: PMC3081414.
      23. Capellini TD, Zappavigna V, Selleri L. Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth. Dev Dyn. 2011 May; 240(5):1063-86. PMID: 21416555; PMCID: PMC3081394.
      24. Capellini TD, Vaccari G, Ferretti E, Fantini S, He M, Pellegrini M, Quintana L, Di Giacomo G, Sharpe J, Selleri L, Zappavigna V. Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1. Development. 2010 Aug 1; 137(15):2559-69. PMID: 20627960; PMCID: PMC2927673.
      25. Mercader N, Selleri L, Criado LM, Pallares P, Parras C, Cleary ML, Torres M. Ectopic Meis1 expression in the mouse limb bud alters P-D patterning in a Pbx1-independent manner. Int J Dev Biol. 2009; 53(8-10):1483-94. PMID: 19247936.
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      26. Capellini TD, Dunn MP, Passamaneck YJ, Selleri L, Di Gregorio A. Conservation of notochord gene expression across chordates: insights from the Leprecan gene family. Genesis. 2008 Nov; 46(11):683-96. PMID: 18798549; PMCID: PMC3065379.
      27. Stankunas K, Shang C, Twu KY, Kao SC, Jenkins NA, Copeland NG, Sanyal M, Selleri L, Cleary ML, Chang CP. Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease. Circ Res. 2008 Sep 26; 103(7):702-9. PMID: 18723445; PMCID: PMC2633052.
      28. Capellini TD, Zewdu R, Di Giacomo G, Asciutti S, Kugler JE, Di Gregorio A, Selleri L. Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15; 321(2):500-14. PMID: 18691704.
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      29. Chung EY, Liu J, Homma Y, Zhang Y, Brendolan A, Saggese M, Han J, Silverstein R, Selleri L, Ma X. Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1. Immunity. 2007 Dec; 27(6):952-64. PMID: 18093541; PMCID: PMC2194654.
      30. Yeh N, Miller JP, Gaur T, Capellini TD, Nikolich-Zugich J, de la Hoz C, Selleri L, Bromage TG, van Wijnen AJ, Stein GS, Lian JB, Vidal A, Koff A. Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130. Mol Cell Biol. 2007 Jul; 27(14):5161-71. PMID: 17502351; PMCID: PMC1951950.
      31. Brendolan A, Rosado MM, Carsetti R, Selleri L, Dear TN. Development and function of the mammalian spleen. Bioessays. 2007 Feb; 29(2):166-77. PMID: 17226804.
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      32. Sanyal M, Tung JW, Karsunky H, Zeng H, Selleri L, Weissman IL, Herzenberg LA, Cleary ML. B-cell development fails in the absence of the Pbx1 proto-oncogene. Blood. 2007 May 15; 109(10):4191-9. PMID: 17244677; PMCID: PMC1885499.
      33. Ferretti E, Villaescusa JC, Di Rosa P, Fernandez-Diaz LC, Longobardi E, Mazzieri R, Miccio A, Micali N, Selleri L, Ferrari G, Blasi F. Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Mol Cell Biol. 2006 Aug; 26(15):5650-62. PMID: 16847320; PMCID: PMC1592771.
      34. Zhang X, Rowan S, Yue Y, Heaney S, Pan Y, Brendolan A, Selleri L, Maas RL. Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development. Dev Biol. 2006 Dec 15; 300(2):748-57. PMID: 17049510.
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      35. Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L. Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development. 2006 Jun; 133(11):2263-73. PMID: 16672333.
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      36. Moens CB, Selleri L. Hox cofactors in vertebrate development. Dev Biol. 2006 Mar 15; 291(2):193-206. PMID: 16515781.
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      37. Di Giacomo G, Koss M, Capellini TD, Brendolan A, Pöpperl H, Selleri L. Spatio-temporal expression of Pbx3 during mouse organogenesis. Gene Expr Patterns. 2006 Oct; 6(7):747-57. PMID: 16434237.
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      38. Brendolan A, Ferretti E, Salsi V, Moses K, Quaggin S, Blasi F, Cleary ML, Selleri L. A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny. Development. 2005 Jul; 132(13):3113-26. PMID: 15944191.
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      39. Manley NR, Selleri L, Brendolan A, Gordon J, Cleary ML. Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol. 2004 Dec 15; 276(2):301-12. PMID: 15581866.
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      40. Rhee JW, Arata A, Selleri L, Jacobs Y, Arata S, Onimaru H, Cleary ML. Pbx3 deficiency results in central hypoventilation. Am J Pathol. 2004 Oct; 165(4):1343-50. PMID: 15466398; PMCID: PMC1618620.
      41. Selleri L, DiMartino J, van Deursen J, Brendolan A, Sanyal M, Boon E, Capellini T, Smith KS, Rhee J, Pöpperl H, Grosveld G, Cleary ML. The TALE homeodomain protein Pbx2 is not essential for development and long-term survival. Mol Cell Biol. 2004 Jun; 24(12):5324-31. PMID: 15169896; PMCID: PMC419882.
      42. Schnabel CA, Selleri L, Cleary ML. Pbx1 is essential for adrenal development and urogenital differentiation. Genesis. 2003 Nov; 37(3):123-30. PMID: 14595835.
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      43. Kim SK, Selleri L, Lee JS, Zhang AY, Gu X, Jacobs Y, Cleary ML. Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus. Nat Genet. 2002 Apr; 30(4):430-5. PMID: 11912494.
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      44. Selleri L, Depew MJ, Jacobs Y, Chanda SK, Tsang KY, Cheah KS, Rubenstein JL, O'Gorman S, Cleary ML. Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation. Development. 2001 Sep; 128(18):3543-57. PMID: 11566859.
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      45. DiMartino JF, Selleri L, Traver D, Firpo MT, Rhee J, Warnke R, O'Gorman S, Weissman IL, Cleary ML. The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver. Blood. 2001 Aug 1; 98(3):618-26. PMID: 11468159.
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      46. Schnabel CA, Selleri L, Jacobs Y, Warnke R, Cleary ML. Expression of Pbx1b during mammalian organogenesis. Mech Dev. 2001 Jan; 100(1):131-5. PMID: 11118899.
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      47. Wlodarska I, Selleri L, La Starza R, Paternotte C, Evans GA, Boogaerts M, Van den Berghe H, Mecucci C. Molecular cytogenetics localizes two new breakpoints on 11q23.3 and 21q11.2 in myelodysplastic syndrome with t(11;21) translocation. Genes Chromosomes Cancer. 1999 Mar; 24(3):199-206. PMID: 10451699.
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      48. Velcich A, Palumbo L, Selleri L, Evans G, Augenlicht L. Organization and regulatory aspects of the human intestinal mucin gene (MUC2) locus. J Biol Chem. 1997 Mar 21; 272(12):7968-76. PMID: 9065467.
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      49. Legius E, Wlodarska I, Selleri L, Evans GA, Wu R, Smet G, Fryns JP. De novo 46,XX, dir dup (11)(q133.3-->q14.2) in a patient with mental retardation, congenital cardiopathy and thrombopenia. Clin Genet. 1996 Apr; 49(4):206-10. PMID: 8828987.
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      50. Quackenbush J, Davies C, Bailis JM, Khristich JV, Diggle K, Marchuck Y, Tobin J, Clark SP, Rodkins A, Marcano S. An STS content map of human chromosome 11: localization of 910 YAC clones and 109 islands. Genomics. 1995 Sep 20; 29(2):512-25. PMID: 8666402.
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      51. Tsang P, Gilles F, Yuan L, Kuo YH, Lupu F, Samara G, Moosikasuwan J, Goye A, Zelenetz AD, Selleri L. A novel L23-related gene 40 kb downstream of the imprinted H19 gene is biallelically expressed in mid-fetal and adult human tissues. Hum Mol Genet. 1995 Sep; 4(9):1499-507. PMID: 8541832.
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      52. Hernández JM, Mecucci C, Beverloo HB, Selleri L, Wlodarska I, Stul M, Michaux L, Verhoef G, Van Orshoven A, Cassiman JJ. Translocation (11;15)(q23;q14) in three patients with acute non-lymphoblastic leukemia (ANLL): clinical, cytogenetic and molecular studies. Leukemia. 1995 Jul; 9(7):1162-6. PMID: 7630191.
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      53. Selleri L, Smith MW, Holmsen AL, Romo AJ, Thomas SD, Paternotte C, Romberg LC, Wei YH, Evans GA. High-resolution physical mapping of a 250-kb region of human chromosome 11q24 by genomic sequence sampling (GSS). Genomics. 1995 Apr 10; 26(3):489-501. PMID: 7607672.
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      54. Luppi M, Morselli M, Emilia G, Temperani P, Marasca R, Barozzi P, Selleri L, Torelli G. Spontaneous loss of Ph chromosome with maintenance of clonal hemopoiesis in an untreated patient with myeloproliferative disease and a long survival. Genes Chromosomes Cancer. 1995 Mar; 12(3):237-40. PMID: 7536465.
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      55. Selleri L, Giovannini M, Hermanson GG, Romo A, Quackenbush J, Penny L, Khristich JV, Evans GA. Yeast artificial chromosome cloning of 3.2 megabases within chromosomal band 11q24 closely linking c-ets 1 and Fli-1 and encompassing the Ewing sarcoma breakpoint. Genomics. 1994 Jul 1; 22(1):137-47. PMID: 7959760.
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      56. Selleri L, Giovannini M, Romo A, Zucman J, Delattre O, Thomas G, Evans GA. Cloning of the entire FLI1 gene, disrupted by the Ewing's sarcoma translocation breakpoint on 11q24, in a yeast artificial chromosome. Cytogenet Cell Genet. 1994; 67(2):129-36. PMID: 8039423.
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      57. Smith MW, Clark SP, Hutchinson JS, Wei YH, Churukian AC, Daniels LB, Diggle KL, Gen MW, Romo AJ, Lin Y. A sequence-tagged site map of human chromosome 11. Genomics. 1993 Sep; 17(3):699-725. PMID: 8244387.
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      58. Djabali M, Selleri L, Parry P, Bower M, Young B, Evans GA. A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias. Nat Genet. 1993 Aug; 4(4):431. PMID: 8401594.
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      59. Giovannini M, Selleri L, Hermanson GG, Evans GA. Localization of the human oncostatin M gene (OSM) to chromosome 22q12, distal to the Ewing's sarcoma breakpoint. Cytogenet Cell Genet. 1993; 62(1):32-4. PMID: 8422753.
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      60. Saleh M, Selleri L, Evans GA. A novel zinc finger gene on human chromosome 1qter that is alternatively spliced in human tissues and cell lines. Am J Hum Genet. 1993 Jan; 52(1):192-203. PMID: 7916577; PMCID: PMC1682137.
      61. Giovannini M, Djabali M, McElligott D, Selleri L, Evans GA. Tandem linkage of genes coding for leukemia inhibitory factor (LIF) and oncostatin M (OSM) on human chromosome 22. Cytogenet Cell Genet. 1993; 64(3-4):240-4. PMID: 8404048.
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      62. Saleh M, Selleri L, Little PF, Evans GA. Isolation and expression of linked zinc finger gene clusters on human chromosome 11q. Genomics. 1992 Dec; 14(4):970-8. PMID: 1339395.
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      63. Eubanks JH, Djabali M, Selleri L, Grandy DK, Civelli O, McElligott DL, Evans GA. Structure and linkage of the D2 dopamine receptor and neural cell adhesion molecule genes on human chromosome 11q23. Genomics. 1992 Dec; 14(4):1010-8. PMID: 1478642.
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      64. Giovannini M, Selleri L, Biegel JA, Scotlandi K, Emanuel BS, Evans GA. Interphase cytogenetics for the detection of the t(11;22)(q24;q12) in small round cell tumors. J Clin Invest. 1992 Nov; 90(5):1911-8. PMID: 1430213; PMCID: PMC443252.
      65. Djabali M, Selleri L, Parry P, Bower M, Young BD, Evans GA. A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias. Nat Genet. 1992 Oct; 2(2):113-8. PMID: 1303259.
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      66. Selleri L, Eubanks JH, Giovannini M, Hermanson GG, Romo A, Djabali M, Maurer S, McElligott DL, Smith MW, Evans GA. Detection and characterization of "chimeric" yeast artificial chromosome clones by fluorescent in situ suppression hybridization. Genomics. 1992 Oct; 14(2):536-41. PMID: 1427876.
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      67. Soekarman D, von Lindern M, van der Plas DC, Selleri L, Bartram CR, Martiat P, Culligan D, Padua RA, Hasper-Voogt KP, Hagemeijer A. Dek-can rearrangement in translocation (6;9)(p23;q34). Leukemia. 1992 Jun; 6(6):489-94. PMID: 1602786.
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      68. Hermanson GG, Lichter P, Selleri L, Ward DC, Evans GA. Cosmid linking clones localized to the long arm of human chromosome 11. Genomics. 1992 May; 13(1):134-43. PMID: 1577478.
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      69. Eubanks JH, Selleri L, Hart R, Rosette C, Evans GA. Isolation, localization, and physical mapping of a highly polymorphic locus on human chromosome 11q13. Genomics. 1991 Nov; 11(3):720-9. PMID: 1685481.
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      70. Torelli G, Marasca R, Luppi M, Selleri L, Ferrari S, Narni F, Mariano MT, Federico M, Ceccherini-Nelli L, Bendinelli M. Human herpesvirus-6 in human lymphomas: identification of specific sequences in Hodgkin's lymphomas by polymerase chain reaction. Blood. 1991 May 15; 77(10):2251-8. PMID: 1674220.
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      71. Selleri L, Hermanson GG, Eubanks JH, Evans GA. Chromosomal in situ hybridization using yeast artificial chromosomes. Genet Anal Tech Appl. 1991 Apr; 8(2):59-66. PMID: 2064820.
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      72. Selleri L, Hermanson GG, Eubanks JH, Lewis KA, Evans GA. Molecular localization of the t(11;22)(q24;q12) translocation of Ewing sarcoma by chromosomal in situ suppression hybridization. Proc Natl Acad Sci U S A. 1991 Feb 1; 88(3):887-91. PMID: 1992479; PMCID: PMC50919.
      73. Sacchi S, Artusi T, Selleri L, Temperani P, Zucchini P, Vecchi A, Emilia G, Torelli U. Sinus histiocytosis with massive lymphadenopathy: immunological, cytogenetic and molecular studies. Blut. 1990 Jun; 60(6):339-44. PMID: 2375964.
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      74. Luppi M, Marasca R, Sola P, Corradi M, Fancinelli M, Montorsi M, Manfredini R, Selleri L. [Mitochondrial DNA deletion in a case of progressive ophthalmoplegia]. Medicina (Firenze). 1990 Apr-Jun; 10(2):166-8. PMID: 2273955.
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      75. Ferrari S, Tagliafico E, D'Incá M, Ceccherelli G, Manfredini R, Selleri L, Donelli A, Sacchi S, Torelli G, Torelli U. Ratios between the abundance of messenger RNA and the corresponding protein of two growth-related genes, c-myc and vimentin, in leukemia blast cells. Cancer Res. 1990 Apr 1; 50(7):1988-91. PMID: 2180559.
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      76. Selleri L, von Lindern M, Hermans A, Meijer D, Torelli G, Grosveld G. Chronic myeloid leukemia may be associated with several bcr-abl transcripts including the acute lymphoid leukemia-type 7 kb transcript. Blood. 1990 Mar 1; 75(5):1146-53. PMID: 2407300.
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      77. Marasca R, Luppi M, Montorsi M, Fancinelli M, Sabbatini R, Mariano MT, Selleri L. [Identification of human herpesvirus HHV-6 sequence in a case of Hodgkin's disease by polymerase chain reaction]. Medicina (Firenze). 1990 Jan-Mar; 10(1):43-5. PMID: 2166207.
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      78. Sacchi S, Temperani P, Selleri L, Zucchini P, Morselli S, Vecchi A, Longo R, Torelli G, Emilia G, Torelli U. Extramedullary pleural blast crisis in chronic myelogenous leukemia: cytogenetic and molecular study. Acta Haematol. 1990; 83(4):198-202. PMID: 2115717.
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      79. Selleri L, Emilia G, Luppi M, Temperani P, Zucchini P, Tagliafico E, Artusi T, Sarti M, Donelli A, Castoldi GL. Chronic myelogenous leukemia with typical clinical and morphological features can be Philadelphia chromosome negative and "bcr negative". Hematol Pathol. 1990; 4(2):67-77. PMID: 2197265.
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      80. Selleri L, Emilia G, Temperani P, Grassilli E, Zucchini P, Tagliafico E, Bonati A, Venezia L, Ferrari S, Torelli U. Philadelphia-positive chronic myelogenous leukemia with typical bcr/abl molecular features and atypical, prolonged survival. Leukemia. 1989 Jul; 3(7):538-42. PMID: 2733455.
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      81. Ferrari S, Tagliafico E, Ceccherelli G, Selleri L, Calabretta B, Donelli A, Temperani P, Sarti M, Sacchi S, Emilia G. Expression of the myeloperoxidase gene in acute and chronic myeloid leukemias: relationship to the expression of cell cycle-related genes. Leukemia. 1989 Jun; 3(6):423-30. PMID: 2542700.
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      82. Emilia G, Temperani P, Ferrari S, Zucchini P, Tagliafico E, Selleri L, Torelli G, Artusi T, Torelli U. Cytogenetic and molecular studies in primary myelofibrosis. Cancer Genet Cytogenet. 1989 Mar; 38(1):101-13. PMID: 2713806.
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      83. Selleri L, Grassilli E, Tagliafico E, Corradi M, Luppi M, Ceccherelli G, Borghi V. [Polymerase chain reaction for the diagnostic identification of HIV infection]. Medicina (Firenze). 1989 Jan-Mar; 9(1):41-3. PMID: 2739527.
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      84. Temperani P, Zucchini P, Emilia G, Sacchi S, Selleri L, Torelli U. Isodicentric X chromosome in myeloproliferative disorders. Acta Haematol. 1989; 81(3):152-4. PMID: 2496563.
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      85. Ferrari S, Calabretta B, Selleri L, Ceccherelli G, Torelli G, Torelli U. Expression of oncogenes and cell cycle related genes in acute and chronic leukemias. Leukemia. 1988 Dec; 2(12 Suppl):160S-166S. PMID: 3199878.
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      86. Hermans A, Selleri L, Gow J, Grosveld GC. Absence of alternative splicing in bcr-abl mRNA in chronic myeloid leukemia cell lines. Blood. 1988 Dec; 72(6):2066-9. PMID: 2848601.
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      87. Hermans A, Gow J, Selleri L, von Lindern M, Hagemeijer A, Wiedemann LM, Grosveld G. bcr-abl oncogene activation in Philadelphia chromosome-positive acute lymphoblastic leukemia. Leukemia. 1988 Oct; 2(10):628-33. PMID: 3172839.
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      88. Tagliafico E, Manfredini R, Selleri L, Zucchini P, Ceccherelli G. [Possible correlations between proliferation and differentiation of blast cells in acute promyelocytic leukemia: a molecular study]. Medicina (Firenze). 1988 Oct-Dec; 8(4):425-8. PMID: 2854184.
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      89. Ferrari S, Mariano MT, Tagliafico E, Sarti M, Ceccherelli G, Selleri L, Merli F, Narni F, Donelli A, Torelli G. Myeloperoxidase gene expression in blast cells with a lymphoid phenotype in cases of acute lymphoblastic leukemia. Blood. 1988 Sep; 72(3):873-6. PMID: 2458150.
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      90. Venturelli D, Lange B, Narni F, Selleri L, Mariano MT, Torelli U, Gewirtz AM, Calabretta B. Prognostic significance of "short-term" effects of chemotherapy on MYC and histone H3 mRNA levels in acute leukemia patients. Proc Natl Acad Sci U S A. 1988 May; 85(10):3590-4. PMID: 3285345; PMCID: PMC280259.
      91. Selleri L, Narni F, Emilia G, Colò A, Zucchini P, Venturelli D, Donelli A, Torelli U, Torelli G. Philadelphia-positive chronic myeloid leukemia with a chromosome 22 breakpoint outside the breakpoint cluster region. Blood. 1987 Nov; 70(5):1659-64. PMID: 3478105.
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      92. Torelli G, Venturelli D, Coló A, Zanni C, Selleri L, Moretti L, Calabretta B, Torelli U. Expression of c-myb protooncogene and other cell cycle-related genes in normal and neoplastic human colonic mucosa. Cancer Res. 1987 Oct 15; 47(20):5266-9. PMID: 3652034.
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      93. Donelli A, Narni F, Tabilio A, Emilia G, Selleri L, Colo A, Zucchini P, Montagnani G, Torelli G, Torelli U. Establishment and characterization of a human IgA-kappa-secreting plasma cell line (MT3). Int J Cancer. 1987 Sep 15; 40(3):383-8. PMID: 3114153.
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      94. Narni F, Colò A, Venturelli D, Selleri L, Donelli A, Tabilio A, Artusi T, Di Prisco U, Torelli G, Torelli U. Immunoglobulin and T-cell receptor beta chain gene rearrangements as lineage markers in human leukemias: a study of 78 cases. Haematologica. 1987 Sep-Oct; 72(5):391-7. PMID: 3121460.
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      95. Emilia G, Sacchi S, Selleri L, Zucchini P, Artusi T, Torelli U. Promyelocytic crisis of chronic myeloid leukaemia. Br J Haematol. 1987 Jun; 66(2):276-7. PMID: 3475112.
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      96. Torelli G, Selleri L, Emilia G, Narni F, Colò A, Zucchini P, Donelli A, Venturelli D, Torelli U. Molecular study of the Philadelphia translocation in chronic myelogenous leukemia in different stages of disease. Haematologica. 1987 May-Jun; 72(3):201-8. PMID: 3040551.
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      97. Torelli UL, Torelli GM, Emilia G, Selleri L, Venturelli D, Artusi T, Donelli A, Colò A, Fornieri C. Simultaneously increased expression of the c-myc and mu chain genes in the acute blastic transformation of a chronic lymphocytic leukaemia. Br J Haematol. 1987 Feb; 65(2):165-70. PMID: 3103669.
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      98. Emilia G, Torelli G, Sacchi S, Zucchini P, Selleri L, Temperani P, Torelli U. Nuclear protrusions and marker chromosomes in lymphocytes of two patients with cutaneous T-cell lymphoma. Acta Haematol. 1987; 78(1):61-2. PMID: 3116814.
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      99. Calabretta B, Kaczmarek L, Selleri L, Torelli G, Ming PM, Ming SC, Mercer WE. Growth-dependent expression of human Mr 53,000 tumor antigen messenger RNA in normal and neoplastic cells. Cancer Res. 1986 Nov; 46(11):5738-42. PMID: 3019534.
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      100. Emilia G, Donelli A, Ferrari S, Torelli U, Selleri L, Zucchini P, Moretti L, Venturelli D, Ceccherelli G, Torelli G. Cellular levels of mRNA from c-myc, c-myb and c-fes onc-genes in normal myeloid and erythroid precursors of human bone marrow: an in situ hybridization study. Br J Haematol. 1986 Feb; 62(2):287-92. PMID: 3947550.
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      101. Torelli U, Selleri L, Venturelli D, Donelli A, Emilia G, Ceccherelli G, Turchi L, Torelli G. Differential patterns of expression of cell cycle-related genes in blast cells of acute myeloid leukemia. Leuk Res. 1986; 10(10):1249-54. PMID: 3464813.
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      102. Torelli G, Selleri L, Donelli A, Ferrari S, Emilia G, Venturelli D, Moretti L, Torelli U. Activation of c-myb expression by phytohemagglutinin stimulation in normal human T lymphocytes. Mol Cell Biol. 1985 Oct; 5(10):2874-7. PMID: 3915538; PMCID: PMC367031.
      103. Ferrari S, Torelli U, Selleri L, Donelli A, Venturelli D, Moretti L, Torelli G. Expression of human c-fes onc-gene occurs at detectable levels in myeloid but not in lymphoid cell populations. Br J Haematol. 1985 Jan; 59(1):21-5. PMID: 3855647.
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      104. Ferrari S, Torelli U, Selleri L, Donelli A, Venturelli D, Narni F, Moretti L, Torelli G. Study of the levels of expression of two oncogenes, c-myc and c-myb, in acute and chronic leukemias of both lymphoid and myeloid lineage. Leuk Res. 1985; 9(7):833-42. PMID: 3860696.
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      105. Emilia G, Sacchi S, Torelli G, Selleri L, Torelli U. Low-dose intravenous pepsin-treated gammaglobulin for idiopathic thrombocytopenic purpura in adults. Br J Haematol. 1984 Dec; 58(4):761-2. PMID: 6542801.
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