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Deepak Srivastava, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
Address1650 Owens St
San Francisco CA 94107
Phone415-734-2716
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine

    Collapse Overview 
    Collapse Overview
    Our laboratory focuses on understanding the causes of heart disease and on using knowledge of cardiac developmental pathways to devise novel therapeutic approaches for human cardiac disorders. Specifically, we study the molecular events regulating early and late developmental decisions that instruct progenitor cells to adopt a cardiac cell fate and subsequently fashion a functioning heart. We focus on transcriptional and post-transcriptional steps, including those involving microRNAs. We have leveraged this knowledge to reprogram fibroblasts directly into cardiomyocyte-like cells for regenerative purposes. We also seek to identify the causes of human cardiovascular disease by applying modern genetic technologies for the study of complex traits such as congenital heart disease. By using a spectrum of approaches including mouse and human genetics, molecular and developmental biology, and biochemistry we hope to develop a broad understanding of the biology underlying cardiogenesis and cardiovascular disorders.

    Collapse Research 
    Collapse Research Activities and Funding
    Aortic Valve Disease: Mechanisms and Therapeutic Approaches
    NIH/NHLBI R01HL150100Feb 10, 2020 - Jan 31, 2024
    Role: Principal Investigator
    Combinatorial Regulation of Gene Networks During Cardiac Development and Disease
    NIH/NHLBI P01HL146366Sep 1, 2019 - Aug 31, 2024
    Role: Principal Investigator
    Cardiogenesis: Molecular Mechanisms
    NIH/NHLBI R01HL057181Dec 24, 2015 - Nov 30, 2014
    Role: Principal Investigator
    Genetics of Hypoplastic Left Heart Syndrome
    NIH/NHLBI UM1HL128761Aug 1, 2015 - Jul 31, 2020
    Role: Principal Investigator
    Regulation of Chromatin Signaling in Heart Failure by the BRD4 Bromodomain Protein.
    NIH/NHLBI R01HL127240Apr 1, 2015 - Mar 31, 2019
    Role: Co-Principal Investigator
    The Epigenetic Landscape of Heart Development
    NIH/NHLBI UM1HL098179Sep 30, 2009 - Jul 31, 2020
    Role: Co-Principal Investigator
    Induced Pluripotent Stem Cells in the Understanding and Treatment of Heart Diseas
    NIH/NHLBI U01HL100406Sep 30, 2009 - Jun 30, 2016
    Role: Principal Investigator
    The Epigenetic Landscape of Heart Development
    NIH/NHLBI U01HL098179Sep 30, 2009 - Jul 31, 2015
    Role: Co-Principal Investigator
    Induced pluripotent stem cells in the understanding and treatment of heart diseas
    NIH/NHLBI R03HL096254Dec 1, 2008 - May 31, 2009
    Role: Principal Investigator
    Mammalian Heart and Lung microRNA Deletion and Distribution Resource
    NIH/NHLBI R24HL092851Sep 1, 2008 - Jul 31, 2012
    Role: Principal Investigator
    Transcriptional Networks During Cardiac Differentiation
    NIH/NHLBI P01HL089707Jul 1, 2007 - May 31, 2013
    Role: Principal Investigator
    Cardiac Defects/Cross-species analysis/Human Mutations
    NIH/NHLBI R01HL080592Jan 15, 2005 - May 31, 2005
    Role: Principal Investigator
    Cardiac Development and Cogenital Heart Disease
    NIH/NICHD R13HD046201Feb 10, 2004 - Feb 9, 2005
    Role: Principal Investigator
    Isolated and Syndromic Cardiac Outflow Tract Defects
    NIH/NHLBI R01HL062591Apr 1, 1999 - Mar 31, 2008
    Role: Principal Investigator
    MOLECULAR BASIS FOR HYPOPLASTIC HEART SYNDROMES
    NIH P50HL061033Jan 1, 1999 - Dec 31, 2003
    Role: Co-Investigator
    Training in Developmental Cardiovascular Biology
    NIH/NHLBI T32HL007544Jul 1, 1983 - Jun 30, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Creating Opportunities to Advance Stem Cell Science: 2019-2020 Year in Review. Stem Cell Reports. 2020 Jun 09; 14(6):993-995. Srivastava D. PMID: 32521249.
      View in: PubMed   Mentions:    Fields:    
    2. Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation. Circ Res. 2019 Sep 13; 125(7):662-677. Stratton MS, Bagchi RA, Felisbino MB, Hirsch RA, Smith HE, Riching AS, Enyart BY, Koch KA, Cavasin MA, Alexanian M, Song K, Qi J, Lemieux ME, Srivastava D, Lam MPY, Haldar SM, Lin CY, McKinsey TA. PMID: 31409188.
      View in: PubMed   Mentions: 1     Fields:    
    3. Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects. Nature. 2019 08; 572(7767):120-124. de Soysa TY, Ranade SS, Okawa S, Ravichandran S, Huang Y, Salunga HT, Schricker A, Del Sol A, Gifford CA, Srivastava D. PMID: 31341279.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    4. Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming. Cell Stem Cell. 2019 07 03; 25(1):87-102.e9. Stone NR, Gifford CA, Thomas R, Pratt KJB, Samse-Knapp K, Mohamed TMA, Radzinsky EM, Schricker A, Ye L, Yu P, van Bemmel JG, Ivey KN, Pollard KS, Srivastava D. PMID: 31271750.
      View in: PubMed   Mentions: 1     Fields:    
    5. Oligogenic inheritance of a human heart disease involving a genetic modifier. Science. 2019 05 31; 364(6443):865-870. Gifford CA, Ranade SS, Samarakoon R, Salunga HT, de Soysa TY, Huang Y, Zhou P, Elfenbein A, Wyman SK, Bui YK, Cordes Metzler KR, Ursell P, Ivey KN, Srivastava D. PMID: 31147515.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    6. The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells. Biol Psychiatry. 2019 07 15; 86(2):120-130. Duarte RRR, Bachtel ND, Côtel MC, Lee SH, Selvackadunco S, Watson IA, Hovsepian GA, Troakes C, Breen GD, Nixon DF, Murray RM, Bray NJ, Eleftherianos I, Vernon AC, Powell TR, Srivastava DP. PMID: 31097295.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System. Front Physiol. 2019; 10:235. Samal E, Evangelista M, Galang G, Srivastava D, Zhao Y, Vedantham V. PMID: 30936836.
      View in: PubMed   Mentions:
    8. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 2018 07 26; 174(3):505-520. Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ. PMID: 30053424.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors. Hum Mutat. 2018 06; 39(6):870-881. Manheimer KB, Patel N, Richter F, Gorham J, Tai AC, Homsy J, Boskovski MT, Parfenov M, Goldmuntz E, Chung WK, Brueckner M, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE, Gelb BD, Sharp AJ. PMID: 29527824.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration. Cell. 2018 03 22; 173(1):104-116.e12. Mohamed TMA, Ang YS, Radzinsky E, Zhou P, Huang Y, Elfenbein A, Foley A, Magnitsky S, Srivastava D. PMID: 29502971.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    11. Erratum to: Etiology and Morphogenesis of Congenital Heart Disease. Etiology and Morphogenesis of Congenital Heart Disease. 2018 Jan 1; e1-e1. Toshio Nakanishi, Roger R. Markwald, H. Scott Baldwin, Bradley B. Keller, Deepak Srivastava, Hiroyuki Yamagishi. .
      View in: Publisher Site   Mentions:
    12. Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands. Nat Genet. 2017 Nov; 49(11):1593-1601. Jin SC, Homsy J, Zaidi S, Lu Q, Morton S, DePalma SR, Zeng X, Qi H, Chang W, Sierant MC, Hung WC, Haider S, Zhang J, Knight J, Bjornson RD, Castaldi C, Tikhonoa IR, Bilguvar K, Mane SM, Sanders SJ, Mital S, Russell MW, Gaynor JW, Deanfield J, Giardini A, Porter GA, Srivastava D, Lo CW, Shen Y, Watkins WS, Yandell M, Yost HJ, Tristani-Firouzi M, Newburger JW, Roberts AE, Kim R, Zhao H, Kaltman JR, Goldmuntz E, Chung WK, Seidman JG, Gelb BD, Seidman CE, Lifton RP, Brueckner M. PMID: 28991257.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    13. A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress. JCI Insight. 2017 Jul 20; 2(14). Judge LM, Perez-Bermejo JA, Truong A, Ribeiro AJ, Yoo JC, Jensen CL, Mandegar MA, Huebsch N, Kaake RM, So PL, Srivastava D, Pruitt BL, Krogan NJ, Conklin BR. PMID: 28724793.
      View in: PubMed   Mentions: 8     Fields:    
    14. BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure. Sci Transl Med. 2017 05 17; 9(390). Duan Q, McMahon S, Anand P, Shah H, Thomas S, Salunga HT, Huang Y, Zhang R, Sahadevan A, Lemieux ME, Brown JD, Srivastava D, Bradner JE, McKinsey TA, Haldar SM. PMID: 28515341.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    15. Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes. Circ Res. 2017 May 12; 120(10):1572-1583. Ribeiro AJS, Schwab O, Mandegar MA, Ang YS, Conklin BR, Srivastava D, Pruitt BL. PMID: 28400398.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency. J Clin Invest. 2017 May 01; 127(5):1683-1688. Theodoris CV, Mourkioti F, Huang Y, Ranade SS, Liu L, Blau HM, Srivastava D. PMID: 28346225.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    17. The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1. Journal of Cell Science. 2017 Mar 15; 130(6):e1.2-e1.2. Jun-yi Zhu, Amy Heidersbach, Irfan S. Kathiriya, Bayardo I. Garay, Kathryn N. Ivey, Deepak Srivastava, Zhe Han, Isabelle N. King. .
      View in: Publisher Site   Mentions:
    18. The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1. Development. 2017 03 01; 144(5):866-875. Zhu JY, Heidersbach A, Kathiriya IS, Garay BI, Ivey KN, Srivastava D, Han Z, King IN. PMID: 28246214.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    19. Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell. 2016 Dec 15; 167(7):1734-1749.e22. Ang YS, Rivas RN, Ribeiro AJS, Srivas R, Rivera J, Stone NR, Pratt K, Mohamed TMA, Fu JD, Spencer CI, Tippens ND, Li M, Narasimha A, Radzinsky E, Moon-Grady AJ, Yu H, Pruitt BL, Snyder MP, Srivastava D. PMID: 27984724.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    20. Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming. Circulation. 2017 Mar 07; 135(10):978-995. Mohamed TM, Stone NR, Berry EC, Radzinsky E, Huang Y, Pratt K, Ang YS, Yu P, Wang H, Tang S, Magnitsky S, Ding S, Ivey KN, Srivastava D. PMID: 27834668.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    21. The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nat Med. 2016 10; 22(10):1131-1139. Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, Vondriska TM, Li G, Deb A, Srivastava D, Yang HT, Xiao X, Li H, Wang Y. PMID: 27618650.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    22. In Vivo Cellular Reprogramming: The Next Generation. Cell. 2016 Sep 08; 166(6):1386-1396. Srivastava D, DeWitt N. PMID: 27610565.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    23. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling. Stem Cell Res Ther. 2016 08 17; 7(1):115. Barruet E, Morales BM, Lwin W, White MP, Theodoris CV, Kim H, Urrutia A, Wong SA, Srivastava D, Hsiao EC. PMID: 27530160.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    24. Effect of biophysical cues on reprogramming to cardiomyocytes. Biomaterials. 2016 10; 103:1-11. Sia J, Yu P, Srivastava D, Li S. PMID: 27376554.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    25. Molecular Regulation of Cardiogenesis. Epstein\u0027s Inborn Errors of Development. 2016 Jun 1; 107-112. Deepak Srivastava, Joseph T. C. Shieh. .
      View in: Publisher Site   Mentions:
    26. Sarcomeres and Cardiac Growth: Tension in the Relationship. Trends Mol Med. 2016 07; 22(7):530-533. Haldar SM, Srivastava D. PMID: 27237981.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    27. Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science. 2016 Jun 03; 352(6290):1216-20. Cao N, Huang Y, Zheng J, Spencer CI, Zhang Y, Fu JD, Nie B, Xie M, Zhang M, Wang H, Ma T, Xu T, Shi G, Srivastava D, Ding S. PMID: 27127239.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    28. Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Sci Rep. 2016 Apr 20; 6:24726. Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, Fox CB, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, Desai TA, So PL, Healy KE, Conklin BR. PMID: 27095412.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    29. Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts. Cell Stem Cell. 2016 Mar 03; 18(3):368-81. Zhang Y, Cao N, Huang Y, Spencer CI, Fu JD, Yu C, Liu K, Nie B, Xu T, Li K, Xu S, Bruneau BG, Srivastava D, Ding S. PMID: 26942852.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    30. Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPases. Neural Plast. 2016; 2016:3025948. Woolfrey KM, Srivastava DP. PMID: 26989514.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    31. A Tuned Tension Regulates the Contractility of Cardiomyocytes Differentiated from Induced Pluripotent Stem Cells. Biophysical Journal. 2016 Feb 1; 110(3):294a. Alexandre J. Ribeiro, Yen-Sin Ang, Robin E. Wilson, Renee N. Rivas, Deepak Srivastava, Beth L. Pruitt. .
      View in: Publisher Site   Mentions:
    32. Efficient CRISPR/Cas9-Based Genome Engineering in Human Pluripotent Stem Cells. Curr Protoc Hum Genet. 2016 Jan 01; 88:21.4.1-21.4.23. Kime C, Mandegar MA, Srivastava D, Yamanaka S, Conklin BR, Rand TA. PMID: 26724721.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    33. A History and Interaction of Outflow Progenitor Cells Implicated in “Takao Syndrome”. Etiology and Morphogenesis of Congenital Heart Disease. 2016 Jan 1; 201-209. Hiroyuki Yamagishi, Kazuki Kodo, Jun Maeda, Keiko Uchida, Takatoshi Tsuchihashi, Akimichi Shibata, Reina Ishizaki, Chihiro Yamagishi, Deepak Srivastava. .
      View in: Publisher Site   Mentions:
    34. Modification of Cardiac Phenotype in Tbx1 Hypomorphic Mice. Etiology and Morphogenesis of Congenital Heart Disease. 2016 Jan 1; 215-217. Takatoshi Tsuchihashi, Reina Ishizaki, Jun Maeda, Akimichi Shibata, Keiko Uchida, Deepak Srivastava, Hiroyuki Yamagishi. .
      View in: Publisher Site   Mentions:
    35. Reprogramming Approaches to Cardiovascular Disease: From Developmental Biology to Regenerative Medicine. Etiology and Morphogenesis of Congenital Heart Disease. 2016 Jan 1; 3-10. Deepak Srivastava. .
      View in: Publisher Site   Mentions:
    36. Heart disease modelling adds a Notch to its belt. Nat Cell Biol. 2016 Jan; 18(1):3-5. Gifford CA, Srivastava D. PMID: 26693916.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Recent advances in direct cardiac reprogramming. Curr Opin Genet Dev. 2015 Oct; 34:77-81. Srivastava D, Yu P. PMID: 26454285.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    38. Practical Integration-Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells. Curr Protoc Hum Genet. 2015 Oct 06; 87:21.2.1-21.2.21. Kime C, Rand TA, Ivey KN, Srivastava D, Yamanaka S, Tomoda K. PMID: 26439714.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    39. Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness. Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41):12705-10. Ribeiro AJ, Ang YS, Fu JD, Rivas RN, Mohamed TM, Higgs GC, Srivastava D, Pruitt BL. PMID: 26417073.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    40. microRNAs as Developmental Regulators. Cold Spring Harb Perspect Biol. 2015 Jul 01; 7(7):a008144. Ivey KN, Srivastava D. PMID: 26134312.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    41. NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium. J Mol Cell Cardiol. 2015 Jul; 84:13-23. White MP, Theodoris CV, Liu L, Collins WJ, Blue KW, Lee JH, Meng X, Robbins RC, Ivey KN, Srivastava D. PMID: 25871831.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    42. Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses. PLoS One. 2015; 10(3):e0121765. Rasmussen TL, Ma Y, Park CY, Harriss J, Pierce SA, Dekker JD, Valenzuela N, Srivastava D, Schwartz RJ, Stewart MD, Tucker HO. PMID: 25803368.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    43. Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency. Cell. 2015 Mar 12; 160(6):1072-86. Theodoris CV, Li M, White MP, Liu L, He D, Pollard KS, Bruneau BG, Srivastava D. PMID: 25768904.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    44. RNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells. Circ Res. 2015 Feb 27; 116(5):797-803. Vedantham V, Galang G, Evangelista M, Deo RC, Srivastava D. PMID: 25623957.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    45. Direct reprogramming of fibroblasts into cardiomyocytes for cardiac regenerative medicine. Circ J. 2015; 79(2):245-54. Fu JD, Srivastava D. PMID: 25744738.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    46. Oxygen: double-edged sword in cardiac function and repair. Circ Res. 2014 Oct 24; 115(10):824-5. Ang YS, Srivastava D. PMID: 25342770.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    47. Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015 Jan 15; 24(2):424-35. Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H. PMID: 25209980.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    48. Specification of the mouse cardiac conduction system in the absence of Endothelin signaling. Dev Biol. 2014 Sep 15; 393(2):245-254. Hua LL, Vedantham V, Barnes RM, Hu J, Robinson AS, Bressan M, Srivastava D, Black BL. PMID: 25050930.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    49. A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data. Nat Biotechnol. 2014 Jul; 32(7):663-9. Hu H, Roach JC, Coon H, Guthery SL, Voelkerding KV, Margraf RL, Durtschi JD, Tavtigian SV, Wu W, Scheet P, Wang S, Xing J, Glusman G, Hubley R, Li H, Garg V, Moore B, Hood L, Galas DJ, Srivastava D, Reese MG, Jorde LB, Yandell M, Huff CD. PMID: 24837662.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    50. The RNA-binding protein TDP-43 selectively disrupts microRNA-1/206 incorporation into the RNA-induced silencing complex. J Biol Chem. 2014 May 16; 289(20):14263-71. King IN, Yartseva V, Salas D, Kumar A, Heidersbach A, Ando DM, Stallings NR, Elliott JL, Srivastava D, Ivey KN. PMID: 24719334.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    51. Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. Cell Rep. 2014 Mar 13; 6(5):951-60. Wang H, Cao N, Spencer CI, Nie B, Ma T, Xu T, Zhang Y, Wang X, Srivastava D, Ding S. PMID: 24561253.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    52. Congenital heart disease: entering a new era of human genetics. Circ Res. 2014 Feb 14; 114(4):598-9. Bruneau BG, Srivastava D. PMID: 24526674.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    53. microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart. Elife. 2013 Nov 19; 2:e01323. Heidersbach A, Saxby C, Carver-Moore K, Huang Y, Ang YS, de Jong PJ, Ivey KN, Srivastava D. PMID: 24252873.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    54. The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes. Cell Stem Cell. 2014 Jan 02; 14(1):40-52. Worringer KA, Rand TA, Hayashi Y, Sami S, Takahashi K, Tanabe K, Narita M, Srivastava D, Yamanaka S. PMID: 24239284.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    55. Direct cardiac reprogramming: from developmental biology to cardiac regeneration. Circ Res. 2013 Sep 13; 113(7):915-21. Qian L, Srivastava D. PMID: 24030021.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    56. Cardiac reprogramming: from mouse toward man. Curr Opin Genet Dev. 2013 Oct; 23(5):574-8. Srivastava D, Berry EC. PMID: 23993230.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    57. Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state. Stem Cell Reports. 2013; 1(3):235-47. Fu JD, Stone NR, Liu L, Spencer CI, Qian L, Hayashi Y, Delgado-Olguin P, Ding S, Bruneau BG, Srivastava D. PMID: 24319660.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    58. Fibronectin mediates mesendodermal cell fate decisions. Journal of Cell Science. 2013 Jun 15; 126(12):e1-e1. P. Cheng, P. Andersen, D. Hassel, B. L. Kaynak, P. Limphong, L. Juergensen, C. Kwon, D. Srivastava. .
      View in: Publisher Site   Mentions:
    59. Fibronectin mediates mesendodermal cell fate decisions. Development. 2013 Jun; 140(12):2587-96. Cheng P, Andersen P, Hassel D, Kaynak BL, Limphong P, Juergensen L, Kwon C, Srivastava D. PMID: 23715551.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    60. Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro. Nat Protoc. 2013 Jun; 8(6):1204-15. Qian L, Berry EC, Fu JD, Ieda M, Srivastava D. PMID: 23722259.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    61. Small solutions to big problems: microRNAs for cardiac regeneration. Circ Res. 2013 May 24; 112(11):1412-4. Srivastava D, Heidersbach AJ. PMID: 23704215.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    62. AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to ß-adrenergic-induced cardiac hypertrophy. PLoS One. 2013; 8(4):e62705. Spindler MJ, Burmeister BT, Huang Y, Hsiao EC, Salomonis N, Scott MJ, Srivastava D, Carnegie GK, Conklin BR. PMID: 23658642.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    63. Fending for a Braveheart. EMBO J. 2013 May 02; 32(9):1211-3. Srivastava D, Cordes Metzler KR. PMID: 23524853.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    64. Modeling human protein aggregation cardiomyopathy using murine induced pluripotent stem cells. Stem Cells Transl Med. 2013 Mar; 2(3):161-6. Limphong P, Zhang H, Christians E, Liu Q, Riedel M, Ivey K, Cheng P, Mitzelfelt K, Taylor G, Winge D, Srivastava D, Benjamin I. PMID: 23430692.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    65. Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem Cells. 2013 Jan; 31(1):92-103. White MP, Rufaihah AJ, Liu L, Ghebremariam YT, Ivey KN, Cooke JP, Srivastava D. PMID: 23079999.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    66. Tam PPL, Nelson WJ, Rossant J, Eds. Mammalian Development: Networks, Switches, and Morphogenetic Processes. MicroRNAs as developmental regulators. 2013; 33–42. Ivey KN Srivastava D..
    67. Stem cells in the land of the rising sun: ISSCR 2012. Cell Stem Cell. 2012 Nov 02; 11(5):607-14. Plath K, Srivastava D, Alvarez-Buylla A, Tanaka EM, Kriegstein AR. PMID: 23122288.
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    68. Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning. Dev Biol. 2013 Jan 01; 373(1):149-62. Vedantham V, Evangelista M, Huang Y, Srivastava D. PMID: 23085412.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    69. A role for RNA post-transcriptional regulation in satellite cell activation. Skelet Muscle. 2012 Oct 09; 2(1):21. Farina NH, Hausburg M, Betta ND, Pulliam C, Srivastava D, Cornelison D, Olwin BB. PMID: 23046558.
      View in: PubMed   Mentions: 13     Fields:    
    70. Cardiac repair with thymosin ß4 and cardiac reprogramming factors. Ann N Y Acad Sci. 2012 Oct; 1270:66-72. Srivastava D, Ieda M, Fu J, Qian L. PMID: 23050819.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    71. Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage. Cell. 2012 Sep 28; 151(1):206-20. Wamstad JA, Alexander JM, Truty RM, Shrikumar A, Li F, Eilertson KE, Ding H, Wylie JN, Pico AR, Capra JA, Erwin G, Kattman SJ, Keller GM, Srivastava D, Levine SS, Pollard KS, Holloway AK, Boyer LA, Bruneau BG. PMID: 22981692.
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    72. MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling. Circ Res. 2012 Nov 09; 111(11):1421-33. Hassel D, Cheng P, White MP, Ivey KN, Kroll J, Augustin HG, Katus HA, Stainier DY, Srivastava D. PMID: 22955733.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    73. Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell. 2012 Jul 06; 11(1):91-9. Tomoda K, Takahashi K, Leung K, Okada A, Narita M, Yamada NA, Eilertson KE, Tsang P, Baba S, White MP, Sami S, Srivastava D, Conklin BR, Panning B, Yamanaka S. PMID: 22770243.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    74. Critical factors for cardiac reprogramming. Circ Res. 2012 Jun 22; 111(1):5-8. Srivastava D, Ieda M. PMID: 22723217.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    75. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature. 2012 May 31; 485(7400):593-8. Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, Liu L, Conway SJ, Fu JD, Srivastava D. PMID: 22522929.
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    76. Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. PLoS Genet. 2012; 8(5):e1002690. Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V. PMID: 22589735.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    77. A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 2012 Apr 19; 1(4):385-91. Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, Richards H, Li Z, Adler D, Yoshinaga Y, Martinez M, Nefadov M, Abbas AK, Weiss A, Lanier LL, de Jong PJ, Bluestone JA, Srivastava D, McManus MT. PMID: 22570807.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    78. Genetics of human cardiovascular disease. Cell. 2012 Mar 16; 148(6):1242-57. Kathiresan S, Srivastava D. PMID: 22424232.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimals
    79. Tbx1 regulates oral epithelial adhesion and palatal development. Hum Mol Genet. 2012 Jun 01; 21(11):2524-37. Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H. PMID: 22371266.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    80. Stem cell therapy for cardiac disease. Pediatr Res. 2012 Apr; 71(4 Pt 2):491-9. Bernstein HS, Srivastava D. PMID: 22430385.
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    81. Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, Eds. Moss and Adams' Heart Disease in Infants, Children and Adolescents. Molecular determinants of cardiac development and disease. 2012. Baldwin HS Srivastava D..
    82. Chromosomal haplotypes by genetic phasing of human families. Am J Hum Genet. 2011 Sep 09; 89(3):382-97. Roach JC, Glusman G, Hubley R, Montsaroff SZ, Holloway AK, Mauldin DE, Srivastava D, Garg V, Pollard KS, Galas DJ, Hood L, Smit AF. PMID: 21855840.
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    83. Notch post-translationally regulates ß-catenin protein in stem and progenitor cells. Nat Cell Biol. 2011 Aug 14; 13(10):1244-51. Kwon C, Cheng P, King IN, Andersen P, Shenje L, Nigam V, Srivastava D. PMID: 21841793.
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    84. Monochorionic twins discordant for congenital heart disease: a referral center's experience and possible pathophysiologic mechanisms. Prenat Diagn. 2011 Oct; 31(10):978-84. AlRais F, Feldstein VA, Srivastava D, Gosnell K, Moon-Grady AJ. PMID: 21744365.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    85. Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. Journal of Experimental Medicine. 2011 Jul 4; 208(7):i20-i20. Li Qian, Joshua D. Wythe, Jiandong Liu, Jerome Cartry, Georg Vogler, Bhagyalaxmi Mohapatra, Robyn T. Otway, Yu Huang, Isabelle N. King, Marjorie Maillet, Yi Zheng, Timothy Crawley, Ouarda Taghli-Lamallem, Christopher Semsarian, Sally Dunwoodie, David Winlaw, Richard P. Harvey, Diane Fatkin, Jeffrey A. Towbin, Jeffery D. Molkentin, Deepak Srivastava, Karen Ocorr, Benoit G. Bruneau, Rolf Bodmer. .
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    86. Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol. 2011 Jun 27; 193(7):1181-96. Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD, Srivastava D, Ocorr K, Bruneau BG, Bodmer R. PMID: 21690310.
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    87. Elevated miR-499 levels blunt the cardiac stress response. PLoS One. 2011 May 09; 6(5):e19481. Shieh JT, Huang Y, Gilmore J, Srivastava D. PMID: 21573063.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimals
    88. A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity. Dev Cell. 2011 Apr 19; 20(4):497-510. King IN, Qian L, Liang J, Huang Y, Shieh JT, Kwon C, Srivastava D. PMID: 21497762.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    89. A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development. 2011 Apr; 138(7):1409-19. Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S. PMID: 21385766.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    90. miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. The Journal of Cell Biology. 2011 Mar 21; 192(6):i7-i7. Li Qian, Linda W. Van Laake, Yu Huang, Siyuan Liu, Michael F. Wendland, Deepak Srivastava. .
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    91. miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. J Exp Med. 2011 Mar 14; 208(3):549-60. Qian L, Van Laake LW, Huang Y, Liu S, Wendland MF, Srivastava D. PMID: 21383058.
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    92. The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science. 2011 Feb 18; 331(6019):912-6. Li Q, Kannan A, DeMayo FJ, Lydon JP, Cooke PS, Yamagishi H, Srivastava D, Bagchi MK, Bagchi IC. PMID: 21330545.
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    93. The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling. Dev Dyn. 2011 Feb; 240(2):384-93. Yu S, Crawford D, Tsuchihashi T, Behrens TW, Srivastava D. PMID: 21246655.
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    94. Rudplph's Pediatrics (Rudolph C, Rudolph A, Lister G, First L, Gershon A, Eds). Control of embryologic cardiac development. 2011. Srivastava D..
    95. Hand2 function in second heart field progenitors is essential for cardiogenesis. Dev Biol. 2011 Mar 01; 351(1):62-9. Tsuchihashi T, Maeda J, Shin CH, Ivey KN, Black BL, Olson EN, Yamagishi H, Srivastava D. PMID: 21185281.
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    96. The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch. Development. 2010 Dec; 137(24):4307-16. Sheehy NT, Cordes KR, White MP, Ivey KN, Srivastava D. PMID: 21098571.
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    97. skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. Proc Natl Acad Sci U S A. 2010 Nov 30; 107(48):20750-5. Park CY, Pierce SA, von Drehle M, Ivey KN, Morgan JA, Blau HM, Srivastava D. PMID: 21071677.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    98. Identification of GATA6 sequence variants in patients with congenital heart defects. Pediatr Res. 2010 Oct; 68(4):281-5. Maitra M, Koenig SN, Srivastava D, Garg V. PMID: 20581743.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    99. Identification of GATA6 Sequence Variants in Patients With Congenital Heart Defects. Pediatric Research. 2010 Oct 1; 68(4):281-285. Meenakshi Maitra, Sara N Koenig, Deepak Srivastava, Vidu Garg. .
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    100. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell. 2010 Aug 06; 142(3):375-86. Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D. PMID: 20691899.
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    101. A novel Slit–Robo–miR-218 signaling axis regulates VEGF-mediated heart tube formation in zebrafish. Developmental Biology. 2010 Aug 1; 344(1):433. Stephanie Woo, Jason E. Fish, Joshua D. Wythe, Benoit B. Bruneau, Didier Y. Stainier, Deepak Srivastava. .
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    102. MicroRNAs as regulators of differentiation and cell fate decisions. Cell Stem Cell. 2010 Jul 02; 7(1):36-41. Ivey KN, Srivastava D. PMID: 20621048.
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    103. Altered microRNAs in bicuspid aortic valve: a comparison between stenotic and insufficient valves. J Heart Valve Dis. 2010 Jul; 19(4):459-65. Nigam V, Sievers HH, Jensen BC, Sier HA, Simpson PC, Srivastava D, Mohamed SA. PMID: 20845893.
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    104. Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. Circ Res. 2010 Aug 06; 107(3):340-7. van Laake LW, Qian L, Cheng P, Huang Y, Hsiao EC, Conklin BR, Srivastava D. PMID: 20558827.
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    105. Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. Journal of Biological Chemistry. 2010 Apr 9; 285(15):11754-11754. Jason E. Fish, Matthew S. Yan, Charles C. Matouk, Rosanne St. Bernard, J. J. David Ho, Anna Gavryushova, Deepak Srivastava, Philip A. Marsden. .
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    106. Thymosin beta4 and cardiac repair. Ann N Y Acad Sci. 2010 Apr; 1194:87-96. Shrivastava S, Srivastava D, Olson EN, DiMaio JM, Bock-Marquette I. PMID: 20536454.
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    107. Monkeying around with cardiac progenitors: hope for the future. J Clin Invest. 2010 Apr; 120(4):1034-6. Qian L, Srivastava D. PMID: 20335651.
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    108. MicroRNAs in cardiac development. Pediatr Cardiol. 2010 Apr; 31(3):349-56. Cordes KR, Srivastava D, Ivey KN. PMID: 20140609.
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    109. Micrornas in bicuspid aortic valve: a comparison between stenosis and insufficiency aortic valve. The Thoracic and Cardiovascular Surgeon. 2010 Feb 1; 58(S 01). SA Mohamed, V Nigam, B Jensen, H Sier, P Simpson, D Srivastava, HH Sievers. .
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    110. Chapter 309 Signaling Pathways Involved in Cardiogenesis. Handbook of Cell Signaling. 2010 Jan 1; 2601-2609. Deepak Srivastava, Chulan Kwon. .
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    111. Chapter 10.3 MicroRNA Regulation of Cardiac Development and Disease. Heart Development and Regeneration. 2010 Jan 1; 729-740. Kimberly R. Cordes, Deepak Srivastava. .
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    112. CHAPTER 9 Aetiology of Congenital Cardiac Disease. Paediatric Cardiology. 2010 Jan 1; 161-171. Benoit G. Bruneau, John Burn, Deepak Srivastava. .
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    113. Paediatric Cardiology (Anderson RH, Baker EJ, Penny D, Redington AN, Rigby ML, Wernovsky G, Eds). The Aetiology of Congenital Cardiac Disease. 2010; 161–171. Bruneau BG, Burn J, Srivastava D..
    114. Heart Development and Regeneration (Rosenthal N, Harvey R, Eds). MicroRNA regulation of cardiac development and disease. 2010; 2:729–740. Cordes KR, Srivastava D..
    115. Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. J Biol Chem. 2010 Jan 08; 285(2):810-26. Fish JE, Yan MS, Matouk CC, St Bernard R, Ho JJ, Ho JJ, Gavryushova A, Srivastava D, Marsden PA. PMID: 19880524.
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    116. Notch1 represses osteogenic pathways in aortic valve cells. J Mol Cell Cardiol. 2009 Dec; 47(6):828-34. Nigam V, Srivastava D. PMID: 19695258.
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    117. A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate. Nat Cell Biol. 2009 Aug; 11(8):951-7. Kwon C, Qian L, Cheng P, Nigam V, Arnold J, Srivastava D. PMID: 19620969.
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    118. Heart malformation: what are the chances it could happen again? Circulation. 2009 Jul 28; 120(4):269-71. Shieh JT, Srivastava D. PMID: 19597046.
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    119. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature. 2009 Aug 06; 460(7256):705-10. Cordes KR, Sheehy NT, White MP, Berry EC, Morton SU, Muth AN, Lee TH, Miano JM, Ivey KN, Srivastava D. PMID: 19578358.
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    120. Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J Mol Cell Cardiol. 2009 May; 46(5):728-38. Bock-Marquette I, Shrivastava S, Pipes GC, Thatcher JE, Blystone A, Shelton JM, Galindo CL, Melegh B, Srivastava D, Olson EN, DiMaio JM. PMID: 19358334.
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    121. MicroRNA regulation of cardiovascular development. Circ Res. 2009 Mar 27; 104(6):724-32. Cordes KR, Srivastava D. PMID: 19325160.
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    122. Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell. 2009 Mar 06; 4(3):198-9; author reply 202. Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. PMID: 19265656.
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    123. Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb; 16(2):233-44. Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D. PMID: 19217425.
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    124. MicroRNAs: opening a new vein in angiogenesis research. Sci Signal. 2009 Jan 06; 2(52):pe1. Fish JE, Srivastava D. PMID: 19126861.
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    125. Handbook of Cell Signaling (Bradshaw RA, Dennis EA, Eds). Signaling pathways involved in cardiogenesis. 2009; 3:2601–2609. Srivastava D, Kwon C.
    126. Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis. Cell Cycle. 2008 Dec 15; 7(24):3815-8. Kwon C, Cordes KR, Srivastava D. PMID: 19066459.
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    127. Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Dev Biol. 2009 Feb 15; 326(2):368-77. Maitra M, Schluterman MK, Nichols HA, Richardson JA, Lo CW, Srivastava D, Garg V. PMID: 19084512.
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    128. Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17824-9. Niu Z, Iyer D, Conway SJ, Martin JF, Ivey K, Srivastava D, Nordheim A, Schwartz RJ. PMID: 19004760.
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    129. microRNA-138 modulates cardiac patterning during embryonic development. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17830-5. Morton SU, Scherz PJ, Cordes KR, Ivey KN, Stainier DY, Srivastava D. PMID: 19004786.
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    130. A rare human sequence variant reveals myocardin autoinhibition. J Biol Chem. 2008 Dec 19; 283(51):35845-52. Ransom JF, King IN, Garg V, Srivastava D. PMID: 18852265.
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    131. miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell. 2008 Aug; 15(2):272-84. Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D. PMID: 18694566.
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    132. Transcriptional regulation during development of the ductus arteriosus. Circ Res. 2008 Aug 15; 103(4):388-95. Ivey KN, Sutcliffe D, Richardson J, Clyman RI, Garcia JA, Srivastava D. PMID: 18635823.
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    133. Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation. 2008 Apr 29; 117(17):2224-31. Saxena A, Fish JE, White MD, Yu S, Smyth JW, Shaw RM, DiMaio JM, Srivastava D. PMID: 18427137.
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    134. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell. 2008 Mar 06; 2(3):219-29. Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D. PMID: 18371447.
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    135. Nonlinear imaging study of extracellular matrix in chemical-induced, developmental dissecting aortic aneurysm: evidence for defective collagen type III. Birth Defects Res A Clin Mol Teratol. 2008 Jan; 82(1):16-24. Gong B, Sun J, Vargas G, Chang Q, Xu Y, Srivastava D, Boor PJ. PMID: 18044709.
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    136. Inborn Errors of Development (Epstein CJ, Ed). Molecular regulation of cardiogenesis. 2008; 124–129. Nigam V, Srivastava D..
    137. Vertebrate heart growth is regulated by functional antagonism between Gridlock and Gata5. Proc Natl Acad Sci U S A. 2007 Aug 28; 104(35):14008-13. Jia H, King IN, Chopra SS, Wan H, Ni TT, Jiang C, Guan X, Wells S, Srivastava D, Zhong TP. PMID: 17715064.
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    138. Thymosin beta4 is cardioprotective after myocardial infarction. Ann N Y Acad Sci. 2007 Sep; 1112:161-70. Srivastava D, Saxena A, Michael Dimaio J, Bock-Marquette I. PMID: 17600280.
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    139. Spectrum of heart disease associated with murine and human GATA4 mutation. J Mol Cell Cardiol. 2007 Dec; 43(6):677-85. Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu WT. PMID: 17643447.
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    140. Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A. 2007 Jun 26; 104(26):10894-9. Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D. PMID: 17576928.
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    141. Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation. 2007 Jun 12; 115(23):3015-38. Pierpont ME, Basson CT, Benson DW, Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL. PMID: 17519398.
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    142. Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proc Natl Acad Sci U S A. 2007 May 08; 104(19):7975-80. Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN. PMID: 17468400.
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    143. Screening and biochemical analysis of GATA4 sequence variations identified in patients with congenital heart disease. Am J Med Genet A. 2007 Apr 15; 143A(8):817-23. Schluterman MK, Krysiak AE, Kathiriya IS, Abate N, Chandalia M, Srivastava D, Garg V. PMID: 17352393.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    144. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell. 2007 Apr 20; 129(2):303-17. Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D. PMID: 17397913.
      View in: PubMed   Mentions: 529     Fields:    Translation:AnimalsCells
    145. A developmental view of microRNA function. Trends Biochem Sci. 2007 Apr; 32(4):189-97. Zhao Y, Srivastava D. PMID: 17350266.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansAnimals
    146. Role of microRNAs in Cardiovascular Biology. Cardiovascular Development. 2007 Jan 1; 18:167-178. Eva Samal, Deepak Srivastava. .
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    147. Advances in Developmental Biology (Bodmer R, Ed). Role of microRNAs in Cardiovascular Biology. 2007; 18:167–178. Samal E, Srivastava D..
    148. The genetics of cardiac birth defects. Semin Cell Dev Biol. 2007 Feb; 18(1):132-9. Ransom J, Srivastava D. PMID: 17240175.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    149. The paradoxical patent ductus arteriosus. J Clin Invest. 2006 Nov; 116(11):2863-5. Ivey KN, Srivastava D. PMID: 17080192.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    150. Erratum: Potential of stem-cell-based therapies for heart disease. Nature. 2006 Nov 1; 444(7118):512-512. Deepak Srivastava, Kathryn N. Ivey. .
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    151. Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition. Circulation. 2006 Oct 24; 114(17):1838-46. Ramana KV, Willis MS, White MD, Horton JW, DiMaio JM, Srivastava D, Bhatnagar A, Srivastava SK. PMID: 17030682.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    152. Making or breaking the heart: from lineage determination to morphogenesis. Cell. 2006 Sep 22; 126(6):1037-48. Srivastava D. PMID: 16990131.
      View in: PubMed   Mentions: 214     Fields:    Translation:HumansAnimalsCells
    153. Stretching to meet needs: integrin-linked kinase and the cardiac pump. Genes Dev. 2006 Sep 01; 20(17):2327-31. Srivastava D, Yu S. PMID: 16951248.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    154. Potential of stem-cell-based therapies for heart disease. Nature. 2006 Jun 29; 441(7097):1097-9. Srivastava D, Ivey KN. PMID: 16810246.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    155. Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development. 2006 Jun; 133(11):2263-73. Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L. PMID: 16672333.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    156. Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jkappa. Biochem Biophys Res Commun. 2006 Jun 23; 345(1):446-52. King IN, Kathiriya IS, Murakami M, Nakagawa M, Gardner KA, Srivastava D, Nakagawa O. PMID: 16682003.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    157. Tbx1 is regulated by forkhead proteins in the secondary heart field. Dev Dyn. 2006 Mar; 235(3):701-10. Maeda J, Yamagishi H, McAnally J, Yamagishi C, Srivastava D. PMID: 16444712.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    158. Sonic hedgehog is essential for first pharyngeal arch development. Pediatr Res. 2006 Mar; 59(3):349-54. Yamagishi C, Yamagishi H, Maeda J, Tsuchihashi T, Ivey K, Hu T, Srivastava D. PMID: 16492970.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    159. Chemical-induced, nonlethal, developmental model of dissecting aortic aneurysm. Birth Defects Res A Clin Mol Teratol. 2006 Jan; 76(1):29-38. Gong B, Trent MB, Srivastava D, Boor PJ. PMID: 16397885.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    160. Genetic regulation of cardiogenesis and congenital heart disease. Annu Rev Pathol. 2006; 1:199-213. Srivastava D. PMID: 18039113.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    161. Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat Genet. 2006 Feb; 38(2):175-83. Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG. PMID: 16380715.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    162. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):18986-91. Kwon C, Han Z, Olson EN, Srivastava D. PMID: 16357195.
      View in: PubMed   Mentions: 145     Fields:    Translation:AnimalsCells
    163. The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell. 2005 Oct 21; 123(2):347-58. Costantini DL, Arruda EP, Agarwal P, Kim KH, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir MG, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui CC, Backx PH, Bruneau BG. PMID: 16239150.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    164. Mutations in NOTCH1 cause aortic valve disease. Nature. 2005 Sep 08; 437(7056):270-4. Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, Grossfeld PD, Srivastava D. PMID: 16025100.
      View in: PubMed   Mentions: 385     Fields:    Translation:HumansAnimalsCells
    165. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature. 2005 Jul 14; 436(7048):214-20. Zhao Y, Samal E, Srivastava D. PMID: 15951802.
      View in: PubMed   Mentions: 560     Fields:    Translation:AnimalsCells
    166. Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype. Dev Biol. 2005 Feb 01; 278(1):155-62. Aiyer AR, Honarpour N, Herz J, Srivastava D. PMID: 15649468.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    167. Principles of Molecular Cardiology (Runge MS, Patterson C, Eds). Genetic underpinnings of cardiogenesis and congenital heart disease. 2005. Garg V, Srivastava D..
    168. Genetic Underpinnings of Cardiogenesis and Congenital Heart Disease. Principles of Molecular Cardiology. 2005 Jan 1; 155-164. Vidu Garg, Deepak Srivastava. .
      View in: Publisher Site   Mentions:
    169. The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development. 2005 Jan; 132(1):189-201. McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN. PMID: 15576406.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    170. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. 2004 Nov 25; 432(7016):466-72. Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D. PMID: 15565145.
      View in: PubMed   Mentions: 198     Fields:    Translation:AnimalsCells
    171. Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. J Biol Chem. 2004 Dec 24; 279(52):54937-43. Kathiriya IS, King IN, Murakami M, Nakagawa M, Astle JM, Gardner KA, Gerard RD, Olson EN, Srivastava D, Nakagawa O. PMID: 15485867.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    172. Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development. 2004 Nov; 131(21):5491-502. Hu T, Yamagishi H, Maeda J, McAnally J, Yamagishi C, Srivastava D. PMID: 15469978.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    173. Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Dev Biol. 2004 Jul 15; 271(2):263-71. Cowan CA, Yokoyama N, Saxena A, Chumley MJ, Silvany RE, Baker LA, Srivastava D, Henkemeyer M. PMID: 15223333.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    174. Heart disease: an ongoing genetic battle? Nature. 2004 Jun 24; 429(6994):819-22. Srivastava D. PMID: 15215849.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    175. Molecular Basis of Cardiovascular Disease: A Companion to Braunwald's Heart Disease (Chien KR, Ed). Cardiac Development and Congenital Heart Disease. 2004. Srivastava D, Olson EN.
    176. Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome. Trends Mol Med. 2003 Sep; 9(9):383-9. Yamagishi H, Srivastava D. PMID: 13129704.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    177. GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature. 2003 Jul 24; 424(6947):443-7. Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, Butler CA, Rothrock CR, Eapen RS, Hirayama-Yamada K, Joo K, Matsuoka R, Cohen JC, Srivastava D. PMID: 12845333.
      View in: PubMed   Mentions: 321     Fields:    Translation:HumansAnimalsCells
    178. Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme. Dev Biol. 2003 Mar 15; 255(2):230-7. Ivey K, Tyson B, Ukidwe P, McFadden DG, Levi G, Olson EN, Srivastava D, Wilkie TM. PMID: 12648486.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    179. Functional attenuation of UFD1l, a 22q11.2 deletion syndrome candidate gene, leads to cardiac outflow septation defects in chicken embryos. Pediatr Res. 2003 Apr; 53(4):546-53. Yamagishi C, Hierck BP, Gittenberger-De Groot AC, Yamagishi H, Srivastava D. PMID: 12612215.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    180. Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev. 2003 Jan 15; 17(2):269-81. Yamagishi H, Maeda J, Hu T, McAnally J, Conway SJ, Kume T, Meyers EN, Yamagishi C, Srivastava D. PMID: 12533514.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    181. Chapter 335 Signaling Pathways Involved in Cardiogenesis. Handbook of Cell Signaling. 2003 Jan 1; (Nature4072000):463-470. Deepak Srivastava. .
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    182. Building a heart: implications for congenital heart disease. J Nucl Cardiol. 2003 Jan-Feb; 10(1):63-70. Srivastava D. PMID: 12569333.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    183. Handbook of Cell Signaling (Bradshaw RA, Dennis EA, Eds). Signaling Pathways Involved in Cardiogenesis. 2003; 3:463–470. Srivastava D..
    184. Genetic and comparative mapping of genes dysregulated in mouse hearts lacking the Hand2 transcription factor gene. Genomics. 2002 Dec; 80(6):593-600. Villanueva MP, Aiyer AR, Muller S, Pletcher MT, Liu X, Emanuel B, Srivastava D, Reeves RH. PMID: 12504851.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    185. Tooth-type specific expression of dHAND/Hand2: possible involvement in murine lower incisor morphogenesis. Cell Tissue Res. 2002 Nov; 310(2):201-12. Abe M, Tamamura Y, Yamagishi H, Maeda T, Kato J, Tabata MJ, Srivastava D, Wakisaka S, Kurisu K. PMID: 12397375.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    186. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat Genet. 2002 May; 31(1):25-32. Gottlieb PD, Pierce SA, Sims RJ, Yamagishi H, Weihe EK, Harriss JV, Maika SD, Kuziel WA, King HL, Olson EN, Nakagawa O, Srivastava D. PMID: 11923873.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    187. Neonatal Cardiology (Artman M, Mahony L, Teitel DF, Eds). Molecular and morphogenetic cardiac embryology: Implications for congenital heart disease. 2002; 1–15. Srivastava D..
    188. Molecular mechanisms of ventricular hypoplasia. Cold Spring Harb Symp Quant Biol. 2002; 67:121-5. Srivastava D, Gottlieb PD, Olson EN. PMID: 12858532.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    189. The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev Biol. 2001 Nov 15; 239(2):190-203. Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, Srivastava D. PMID: 11784028.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    190. A common cis-acting sequence in the DiGeorge critical region regulates bi-directional transcription of UFD1L and CDC45L. Mech Dev. 2001 Oct; 108(1-2):81-92. Kunte A, Ivey K, Yamagishi C, Garg V, Yamagishi H, Srivastava D. PMID: 11578863.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    191. Human eHAND, but not dHAND, is down-regulated in cardiomyopathies. J Mol Cell Cardiol. 2001 Sep; 33(9):1607-14. Natarajan A, Yamagishi H, Ahmad F, Li D, Roberts R, Matsuoka R, Hill S, Srivastava D. PMID: 11549340.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    192. Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development. Dev Biol. 2001 Jul 01; 235(1):62-73. Garg V, Yamagishi C, Hu T, Kathiriya IS, Yamagishi H, Srivastava D. PMID: 11412027.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    193. CHAMP, a novel cardiac-specific helicase regulated by MEF2C. Dev Biol. 2001 Jun 15; 234(2):497-509. Liu ZP, Nakagawa O, Nakagawa M, Yanagisawa H, Passier R, Richardson JA, Srivastava D, Olson EN. PMID: 11397016.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    194. Genetic assembly of the heart: implications for congenital heart disease. Annu Rev Physiol. 2001; 63:451-69. Srivastava D. PMID: 11181963.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    195. Encyclopedia of Molecular Medicine (Creighton TE and Kazazian HH, Eds). HAND transcription factors. 2001. Olson EN, Srivastava D..
    196. Moss and Adams' Heart Disease in Infants, Children, and Adolescents (Allen HD, Gutsgell HP, Clark EB, Driscoll DJ, Eds). Molecular determinants of cardiac development. 2001. Srivastava D, Baldwin HS.
    197. Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. Proc Natl Acad Sci U S A. 2000 Dec 05; 97(25):13655-60. Nakagawa O, McFadden DG, Nakagawa M, Yanagisawa H, Hu T, Srivastava D, Olson EN. PMID: 11095750.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    198. A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart. Development. 2000 Dec; 127(24):5331-41. McFadden DG, Charité J, Richardson JA, Srivastava D, Firulli AB, Olson EN. PMID: 11076755.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    199. Apoptosis during cardiovascular development. Circ Res. 2000 Nov 10; 87(10):856-64. Fisher SA, Langille BL, Srivastava D. PMID: 11073880.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    200. A genetic blueprint for cardiac development. Nature. 2000 Sep 14; 407(6801):221-6. Srivastava D, Olson EN. PMID: 11001064.
      View in: PubMed   Mentions: 160     Fields:    Translation:Animals
    201. Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development. Mech Dev. 2000 Jul; 95(1-2):231-7. Angelo S, Lohr J, Lee KH, Ticho BS, Breitbart RE, Hill S, Yost HJ, Srivastava D. PMID: 10906469.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    202. Congenital heart defects: trapping the genetic culprits. Circ Res. 2000 May 12; 86(9):917-8. Srivastava D. PMID: 10807859.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    203. Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway. Development. 2000 May; 127(10):2133-42. Fernandez-Teran M, Piedra ME, Kathiriya IS, Srivastava D, Rodriguez-Rey JC, Ros MA. PMID: 10769237.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    204. The basic helix-loop-helix transcription factor, dHAND, is required for vascular development. J Clin Invest. 2000 Feb; 105(3):261-70. Yamagishi H, Olson EN, Srivastava D. PMID: 10675351.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    205. DiGeorge syndrome: an enigma in mice and men. Mol Med Today. 2000 Jan; 6(1):13-4. Srivastava D. PMID: 10637569.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    206. Left-right asymmetry and cardiac looping: implications for cardiac development and congenital heart disease. Am J Med Genet. 2000; 97(4):271-9. Kathiriya IS, Srivastava D. PMID: 11376438.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    207. Etiology and Morphogenesis of Congenital Heart Disease (Clark EB, Nakazawa M, Takao A, Eds). Role of the bHLH transcription factor, dHAND, in cranial/cardiac neural crest development. 2000; 325–328. Yamagishi H, Srivastava D..
    208. Etiology and Morphogenesis of Congenital Heart Disease (Takao A, Nakazawa M, Clark EB, Eds). Understanding CHD through dissection of segmental cardiac molecular pathways. 2000; 205–210. Srivastava D..
    209. HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev Biol. 1999 Dec 01; 216(1):72-84. Nakagawa O, Nakagawa M, Richardson JA, Olson EN, Srivastava D. PMID: 10588864.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    210. Developmental and genetic aspects of congenital heart disease. Curr Opin Cardiol. 1999 May; 14(3):263-8. Srivastava D. PMID: 10358798.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    211. A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects. Science. 1999 Feb 19; 283(5405):1158-61. Yamagishi H, Garg V, Matsuoka R, Thomas T, Srivastava D. PMID: 10024240.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    212. HAND proteins: molecular mediators of cardiac development and congenital heart disease. Trends Cardiovasc Med. 1999 Jan-Feb; 9(1-2):11-8. Srivastava D. PMID: 10189962.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    213. Heart Development (Rosenthal N and Harvey R, Eds). Segmental regulation of cardiac development by the basic helix-loop-helix transcription factors dHAND and eHAND. 1999; 143–155. Srivastava D..
    214. 9 Segmental Regulation of Cardiac Development by the Basic Helix-Loop-Helix Transcription Factors dHAND and eHAND. Heart Development. 1999 Jan 1; (Mol. Cell. Biol.131993):143-155. Deepak Srivastava. .
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    215. A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme. Development. 1998 Aug; 125(16):3005-14. Thomas T, Kurihara H, Yamagishi H, Kurihara Y, Yazaki Y, Olson EN, Srivastava D. PMID: 9671575.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    216. The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness. Dev Biol. 1998 Apr 15; 196(2):228-36. Thomas T, Yamagishi H, Overbeek PA, Olson EN, Srivastava D. PMID: 9576835.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    217. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet. 1998 Mar; 18(3):266-70. Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN. PMID: 9500550.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    218. Left, right ... which way to turn? Nat Genet. 1997 Nov; 17(3):252-4. Srivastava D. PMID: 9354777.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    219. Knowing in your heart what's right. Trends Cell Biol. 1997 Nov; 7(11):447-53. Srivastava D, Olson EN. PMID: 17709004.
      View in: PubMed   Mentions: 10     Fields:    
    220. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet. 1997 Jun; 16(2):154-60. Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, Olson EN. PMID: 9171826.
      View in: PubMed   Mentions: 133     Fields:    Translation:AnimalsCells
    221. Genetic Control of Heart Development (Harvey RP, Olson EN, Schulz RA, Altman JS, Eds). The bHLH proteins, dHAND and eHAND in cardiac development. 1997. Srivastava D..
    222. A transcriptional pathway for cardiac development. Cold Spring Harb Symp Quant Biol. 1997; 62:405-11. Lin Q, Srivastava D, Olson EN. PMID: 9598375.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    223. Neurotrophin-3 knocks heart off Trk. Nat Med. 1996 Oct; 2(10):1069-71. Srivastava D, Olson EN. PMID: 8837596.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    224. Molecular pathways controlling heart development. Science. 1996 May 03; 272(5262):671-6. Olson EN, Srivastava D. PMID: 8614825.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    225. A subclass of bHLH proteins required for cardiac morphogenesis. Science. 1995 Dec 22; 270(5244):1995-9. Srivastava D, Cserjesi P, Olson EN. PMID: 8533092.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    226. Hepatic venous blood and the development of pulmonary arteriovenous malformations in congenital heart disease. Circulation. 1995 Sep 01; 92(5):1217-22. Srivastava D, Preminger T, Lock JE, Mandell V, Keane JF, Mayer JE, Kozakewich H, Spevak PJ. PMID: 7648668.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    227. Two glucocorticoid binding sites on the human glucocorticoid receptor. Endocrinology. 1990 Oct; 127(4):1770-8. Srivastava D, Thompson EB. PMID: 2205477.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    228. Interactions of the phenylpyrazolo steroid cortivazol with glucocorticoid receptors in steroid-sensitive and -resistant human leukemic cells. Cancer Res. 1989 Apr 15; 49(8 Suppl):2253s-2258s. Thompson EB, Srivastava D, Johnson BH. PMID: 2702665.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
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