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    Martina Descovich, PhD

    TitleAssociate Professor
    SchoolUCSF School of Medicine
    DepartmentRadiation Oncology
    Address1600 Divisadero
    San Francisco CA 94115
    Phone415-353-9844
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      Collapse Biography 
      Collapse Education and Training
      University of Padua, ItalyBS/MSPhysics1999
      University of Liverpoool, UKPh.D.Nuclear Physics2003
      Lawrence Berkeley National Lab.Postdoctoral StudiesNuclear Science2005
      University of California, San FranciscoPhysics ResidencyRadiation Oncology2007

      Collapse Overview 
      Collapse Overview
      Dr. Descovich specializes in the physics of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT). SRS and SBRT are advanced modalities of radiation therapy, enabling high targeting accuracy. The CyberKnife system is a medical device entirely dedicated to SRS and SBRT treatments. It combines a sophisticated tracking system with a robotically mounted linear accelerator capable of delivering radiation from hundreds of different directions while synchronizing with respiratory induced target motion. Radiosurgery treatments are complex and require a team of specialized experts. Dr. Descovich has been the lead physicist responsible for the CyberKnife program since the installation of the CyberKnife VSI at Helen Diller Family Comprehensive Cancer Center in 2010.

      Collapse Interests
      CyberKnife; stereotactic radiosurgery; stereotactic body radiation therapy; motion management

      Collapse ORNG Applications 
      Collapse Websites

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. McGuinness CM, Gottschalk AR, Lessard E, Nakamura JL, Pinnaduwage D, Pouliot J, Sims C, Descovich M. Investigating the clinical advantages of a robotic linac equipped with a multileaf collimator in the treatment of brain and prostate cancer patients. J Appl Clin Med Phys. 2015; 16(5):5502. PMID: 26699309.
        View in: PubMed
      2. Goggin LM, Descovich M, McGuinness C, Shiao S, Pouliot J, Park C. Dosimetric Comparison Between 3-Dimensional Conformal and Robotic SBRT Treatment Plans for Accelerated Partial Breast Radiotherapy. Technol Cancer Res Treat. 2016 Jun; 15(3):437-45. PMID: 26335703.
        View in: PubMed
      3. Seymour ZA, Chang AJ, Zhang L, Kirby N, Descovich M, Roach M, Hsu IC, Gottschalk AR. Dose-volume analysis and the temporal nature of toxicity with stereotactic body radiation therapy for prostate cancer. Pract Radiat Oncol. 2015 Sep-Oct; 5(5):e465-72. PMID: 25795252.
        View in: PubMed
      4. Descovich M, McGuinness C, Kannarunimit D, Chen J, Pinnaduwage D, Pouliot J, Kased N, Gottschalk AR, Yom SS. Comparison between target margins derived from 4DCT scans and real-time tumor motion tracking: insights from lung tumor patients treated with robotic radiosurgery. Med Phys. 2015 Mar; 42(3):1280-7. PMID: 25735283.
        View in: PubMed
      5. Kannarunimit D, Descovich M, Garcia A, Chen J, Weinberg V, Mcguinness C, Pinnaduwage D, Murnane J, Gottschalk AR, Yom SS. Analysis of dose distribution and risk of pneumonitis in stereotactic body radiation therapy for centrally located lung tumors: a comparison of robotic radiosurgery, helical tomotherapy and volumetric modulated arc therapy. Technol Cancer Res Treat. 2015 Feb; 14(1):49-60. PMID: 24325136.
        View in: PubMed
      6. Descovich M, Carrara M, Morlino S, Pinnaduwage DS, Saltiel D, Pouliot J, Nash MB, Pignoli E, Valdagni R, Roach M, Gottschalk AR. Improving plan quality and consistency by standardization of dose constraints in prostate cancer patients treated with CyberKnife. J Appl Clin Med Phys. 2013; 14(5):162-72. PMID: 24036869.
        View in: PubMed
      7. Descovich M, Ma L, Chuang CF, Larson DA, Barani IJ. Comparison between prone and supine patient setup for spine stereotactic body radiosurgery. Technol Cancer Res Treat. 2012 Jun; 11(3):229-36. PMID: 22468994.
        View in: PubMed
      8. Shiao SL, Sahgal A, Hu W, Jabbari S, Chuang C, Descovich M, Hsu IC, Gottschalk AR, Roach M, Ma L. Temporal compartmental dosing effects for robotic prostate stereotactic body radiotherapy. Phys Med Biol. 2011 Dec 21; 56(24):7767-75. PMID: 22107791.
        View in: PubMed
      9. Ma L, Sahgal A, Hwang A, Hu W, Descovich M, Chuang C, Barani I, Sneed PK, McDermott M, Larson DA. A two-step optimization method for improving multiple brain lesion treatments with robotic radiosurgery. Technol Cancer Res Treat. 2011 Aug; 10(4):331-8. PMID: 21728390.
        View in: PubMed
      10. Ma L, Petti P, Wang B, Descovich M, Chuang C, Barani IJ, Kunwar S, Shrieve DC, Sahgal A, Larson DA. Apparatus dependence of normal brain tissue dose in stereotactic radiosurgery for multiple brain metastases. J Neurosurg. 2011 Jun; 114(6):1580-4. PMID: 21375377.
        View in: PubMed
      11. Jabbari S, Weinberg VK, Kaprealian T, Hsu IC, Ma L, Chuang C, Descovich M, Shiao S, Shinohara K, Roach M, Gottschalk AR. Stereotactic body radiotherapy as monotherapy or post-external beam radiotherapy boost for prostate cancer: technique, early toxicity, and PSA response. Int J Radiat Oncol Biol Phys. 2012 Jan 1; 82(1):228-34. PMID: 21183287.
        View in: PubMed
      12. Descovich M, Sneed PK, Barbaro NM, McDermott MW, Chuang CF, Barani IJ, Nakamura JL, Lijun M. A dosimetric comparison between Gamma Knife and CyberKnife treatment plans for trigeminal neuralgia. J Neurosurg. 2010 Dec; 113 Suppl:199-206. PMID: 21222296.
        View in: PubMed
      13. Ma L, Sahgal A, Descovich M, Cho YB, Chuang C, Huang K, Laperriere NJ, Shrieve DC, Larson DA. Equivalence in dose fall-off for isocentric and nonisocentric intracranial treatment modalities and its impact on dose fractionation schemes. Int J Radiat Oncol Biol Phys. 2010 Mar 1; 76(3):943-8. PMID: 20159366.
        View in: PubMed
      14. Hossain S, Xia P, Huang K, Descovich M, Chuang C, Gottschalk AR, Roach M, Ma L. Dose gradient near target-normal structure interface for nonisocentric CyberKnife and isocentric intensity-modulated body radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys. 2010 Sep 1; 78(1):58-63. PMID: 20133073.
        View in: PubMed
      15. Descovich M, Fowble B, Bevan A, Schechter N, Park C, Xia P. Comparison between hybrid direct aperture optimized intensity-modulated radiotherapy and forward planning intensity-modulated radiotherapy for whole breast irradiation. Int J Radiat Oncol Biol Phys. 2010 Jan 1; 76(1):91-9. PMID: 19395189.
        View in: PubMed
      16. Ma L, Sahgal A, Hossain S, Chuang C, Descovich M, Huang K, Gottschalk A, Larson DA. Nonrandom intrafraction target motions and general strategy for correction of spine stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys. 2009 Nov 15; 75(4):1261-5. PMID: 19647951.
        View in: PubMed
      17. Morin O, Aubry JF, Aubin M, Chen J, Descovich M, Hashemi AB, Pouliot J. Physical performance and image optimization of megavoltage cone-beam CT. Med Phys. 2009 Apr; 36(4):1421-32. PMID: 19472649.
        View in: PubMed
      18. Ma L, Verhey L, Chuang C, Descovich M, Smith V, Huang K, McDermott M, Sneed P. Effect of composite sector collimation on average dose fall-off for Gamma Knife Perfexion. J Neurosurg. 2008 Dec; 109 Suppl:15-20. PMID: 19123883.
        View in: PubMed
      19. Ma L, Chuang C, Descovich M, Petti P, Smith V, Verhey L. Whole-procedure clinical accuracy of gamma knife treatments of large lesions. Med Phys. 2008 Nov; 35(11):5110-4. PMID: 19070245.
        View in: PubMed
      20. Descovich M, Morin O, Aubry JF, Aubin M, Chen J, Bani-Hashemi A, Pouliot J. Characteristics of megavoltage cone-beam digital tomosynthesis. Med Phys. 2008 Apr; 35(4):1310-6. PMID: 18491525.
        View in: PubMed
      21. Morin O, Gillis A, Descovich M, Chen J, Aubin M, Aubry JF, Chen H, Gottschalk AR, Xia P, Pouliot J. Patient dose considerations for routine megavoltage cone-beam CT imaging. Med Phys. 2007 May; 34(5):1819-27. PMID: 17555263.
        View in: PubMed
      22. Morin O, Chen J, Aubin M, Gillis A, Aubry JF, Bose S, Chen H, Descovich M, Xia P, Pouliot J. Dose calculation using megavoltage cone-beam CT. Int J Radiat Oncol Biol Phys. 2007 Mar 15; 67(4):1201-10. PMID: 17336221.
        View in: PubMed
      23. Hansen EK, Larson DA, Aubin M, Chen J, Descovich M, Gillis AM, Morin O, Xia P, Pouliot J. Image-guided radiotherapy using megavoltage cone-beam computed tomography for treatment of paraspinous tumors in the presence of orthopedic hardware. Int J Radiat Oncol Biol Phys. 2006 Oct 1; 66(2):323-6. PMID: 16965986.
        View in: PubMed
      24. Stephens FS, Deleplanque MA, Lee IY, Macchiavelli AO, Ward D, Fallon P, Cromaz M, Clark RM, Descovich M, Diamond RM, Rodriguez-Vieitez E. Order-to-chaos transition in rotational nuclei. Phys Rev Lett. 2005 Feb 4; 94(4):042501. PMID: 15783551.
        View in: PubMed
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