Jean Nakamura, MD
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Title | Associate Professor |
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School | UCSF School of Medicine |
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Department | Radiation Oncology |
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Address | 1450 Third St San Francisco CA 94158
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Phone | 415-514-4995 |
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vCard | Download vCard |
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Biography University of Chicago | M.D. | 1998 | Pritzker School of Medicine |
Research ORNG Applications Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Thibodeau BJ, Lavergne V, Dekhne N, Benitez P, Amin M, Ahmed S, Nakamura JL, Davidson PR, Nakamura J, Grills IS, Chen PY, Wobb J, Wilson GD. Mutational landscape of radiation-associated angiosarcoma of the breast. Oncotarget. 2018 Feb 09; 9(11):10042-10053. PMID: 29515789.
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Davidson PR, Sherborne AL, Taylor B, Nakamura AO, Nakamura J. A pooled mutational analysis identifies ionizing radiation-associated mutational signatures conserved between mouse and human malignancies. Sci Rep. 2017 Aug 09; 7(1):7645. PMID: 28794481.
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Imber BS, Kanungo I, Braunstein S, Barani IJ, Fogh SE, Nakamura J, Berger MS, Chang EF, Molinaro AM, Cabrera JR, McDermott MW, Sneed PK, Aghi MK. Indications and Efficacy of Gamma Knife Stereotactic Radiosurgery for Recurrent Glioblastoma: 2 Decades of Institutional Experience. Neurosurgery. 2017 01 01; 80(1):129-139. PMID: 27428784.
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Sherborne A, Lavergne V, Yu K, Lee L, Davidson P, Mazor T, Smirnov IV, Horvai AE, Loh M, Dubois SG, Goldsby R, Neglia JP, Hammond S, Robison LL, Wustrack R, Costello JF, Nakamura A, Shannon KM, Bhatia S, Nakamura J. Somatic and Germline TP53 Alterations in Second Malignant Neoplasms from Pediatric Cancer Survivors. Clin Cancer Res. 2017 Apr 01; 23(7):1852-1861. PMID: 27683180.
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Garcia MA, Lazar A, Duriseti S, Raleigh DR, Hess CP, Fogh SE, Barani IJ, Nakamura J, Larson DA, Theodosopoulos P, McDermott M, Sneed PK, Braunstein S. Discovery of additional brain metastases on the day of stereotactic radiosurgery: risk factors and outcomes. J Neurosurg. 2017 Jun; 126(6):1756-1763. PMID: 27367235.
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Kaprealian T, Raleigh DR, Sneed PK, Nabavizadeh N, Nakamura J, McDermott MW. Parameters influencing local control of meningiomas treated with radiosurgery. J Neurooncol. 2016 06; 128(2):357-64. PMID: 27131883.
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Held M, Cremers F, Sneed PK, Braunstein S, Fogh SE, Nakamura J, Barani I, Perez-Andujar A, Pouliot J, Morin O. Assessment of image quality and dose calculation accuracy on kV CBCT, MV CBCT, and MV CT images for urgent palliative radiotherapy treatments. J Appl Clin Med Phys. 2016 03 08; 17(2):279-290. PMID: 27074487.
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McGuinness CM, Gottschalk AR, Lessard E, Nakamura J, Pinnaduwage D, Pouliot J, Sims C, Descovich M. Investigating the clinical advantages of a robotic linac equipped with a multileaf collimator in the treatment of brain and prostate cancer patients. J Appl Clin Med Phys. 2015 09 08; 16(5):284–295. PMID: 26699309.
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Sherborne AL, Davidson PR, Yu K, Nakamura AO, Rashid M, Nakamura J. Mutational Analysis of Ionizing Radiation Induced Neoplasms. Cell Rep. 2015 Sep 22; 12(11):1915-26. PMID: 26344771.
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Mroue R, Huang B, Braunstein S, Firestone AJ, Nakamura J. Correction: Monoallelic Loss of the Imprinted Gene Grb10 Promotes Tumor Formation in Irradiated Nf1+/- Mice. PLoS Genet. 2015 Jun; 11(6):e1005327. PMID: 26075392; PMCID: PMC4468248.
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Mroue R, Huang B, Braunstein S, Firestone AJ, Nakamura J. Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice. PLoS Genet. 2015 May; 11(5):e1005235. PMID: 26000738; PMCID: PMC4441450.
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Sneed PK, Mendez J, Vemer-van den Hoek JG, Seymour ZA, Ma L, Molinaro AM, Fogh SE, Nakamura J, McDermott MW. Adverse radiation effect after stereotactic radiosurgery for brain metastases: incidence, time course, and risk factors. J Neurosurg. 2015 Aug; 123(2):373-86. PMID: 25978710.
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Seymour ZA, Fogh SE, Westcott SK, Braunstein S, Larson DA, Barani IJ, Nakamura J, Sneed PK. Interval From Imaging to Treatment Delivery in the Radiation Surgery Age: How Long Is Too Long? Int J Radiat Oncol Biol Phys. 2015 Sep 01; 93(1):126-32. PMID: 26279030.
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Li N, Maly DJ, Chanthery YH, Sirkis DW, Nakamura J, Berger MS, James CD, Shokat KM, Weiss WA, Persson AI. Radiotherapy followed by aurora kinase inhibition targets tumor-propagating cells in human glioblastoma. Mol Cancer Ther. 2015 Feb; 14(2):419-28. PMID: 25522764; PMCID: PMC4326592.
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Ma L, Sahgal A, Larson DA, Pinnaduwage D, Fogh S, Barani I, Nakamura J, McDermott M, Sneed P. Impact of millimeter-level margins on peripheral normal brain sparing for gamma knife radiosurgery. Int J Radiat Oncol Biol Phys. 2014 May 01; 89(1):206-13. PMID: 24725703.
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Fouse SD, Nakamura J, James CD, Chang S, Costello JF. Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype. Neuro Oncol. 2014 Mar; 16(3):361-71. PMID: 24311636; PMCID: PMC3922516.
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Braunstein S, Nakamura J. Radiotherapy-induced malignancies: review of clinical features, pathobiology, and evolving approaches for mitigating risk. Front Oncol. 2013; 3:73. PMID: 23565507; PMCID: PMC3615242.
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Wahl M, Hwang A, Nakamura J, Barani I, Fogh S, Sneed P, McDermott M, Sahgal A, Ma L. Individual beam sharpening improves composite dose fall-off near a target for non-isocentric cyberknife radiosurgery. Technol Cancer Res Treat. 2013 Aug; 12(4):341-8. PMID: 23369157.
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Fogh S, Ma L, Gupta N, Sahgal A, Nakamura J, Barani I, Sneed PK, McDermott M, Larson DA. High-precision volume-staged Gamma Knife surgery and equivalent hypofractionation dose schedules for treating large arteriovenous malformations. J Neurosurg. 2012 Dec; 117 Suppl:115-9. PMID: 23205798.
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Choi G, Huang B, Pinarbasi E, Braunstein SE, Horvai AE, Kogan S, Bhatia S, Faddegon B, Nakamura J. Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms. Cancer Res. 2012 Dec 15; 72(24):6425-34. PMID: 23071067; PMCID: PMC3787120.
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Ma L, Fogh S, Gupta N, Hwang A, Pinnaduwage D, Nakamura J, Barani I, McDermott M, Sneed PK, Larson DA, Sahgal A. A technique for achieving submillimeter accuracy of volume-staged stereotactic radiosurgery. J Radiosurg SBRT. 2012; 2(1):11-17. PMID: 29296338.
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Caballero JA, Sneed PK, Lamborn KR, Ma L, Denduluri S, Nakamura J, Barani IJ, McDermott MW. Prognostic factors for survival in patients treated with stereotactic radiosurgery for recurrent brain metastases after prior whole brain radiotherapy. Int J Radiat Oncol Biol Phys. 2012 May 01; 83(1):303-9. PMID: 22079723.
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Ma L, Lee L, Barani I, Hwang A, Fogh S, Nakamura J, McDermott M, Sneed P, Larson DA, Sahgal A. Shot sequencing based on biological equivalent dose considerations for multiple isocenter Gamma Knife radiosurgery. Phys Med Biol. 2011 Nov 21; 56(22):7247-56. PMID: 22037677.
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Nakamura J, Phong C, Pinarbasi E, Kogan SC, Vandenberg S, Horvai AE, Faddegon BA, Fiedler D, Shokat K, Houseman BT, Chao R, Pieper RO, Shannon K. Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice. Cancer Res. 2011 Jan 01; 71(1):106-15. PMID: 21199799; PMCID: PMC3077533.
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Kased N, Binder DK, McDermott MW, Nakamura J, Huang K, Berger MS, Wara WM, Sneed PK. Gamma Knife radiosurgery for brain metastases from primary breast cancer. Int J Radiat Oncol Biol Phys. 2009 Nov 15; 75(4):1132-40. PMID: 19345514.
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Golden DW, Lamborn KR, McDermott MW, Kunwar S, Wara WM, Nakamura J, Sneed PK. Prognostic factors and grading systems for overall survival in patients treated with radiosurgery for brain metastases: variation by primary site. J Neurosurg. 2008 Dec; 109 Suppl:77-86. PMID: 19123892.
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Nakamura J, Garcia E, Pieper RO. S6K1 plays a key role in glial transformation. Cancer Res. 2008 Aug 15; 68(16):6516-23. PMID: 18701474; PMCID: PMC2538583.
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Nakamura J, Haas-Kogan DA, Pieper RO. Glioma invasiveness responds variably to irradiation in a co-culture model. Int J Radiat Oncol Biol Phys. 2007 Nov 01; 69(3):880-6. PMID: 17889268.
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Kased N, Huang K, Nakamura J, Sahgal A, Larson DA, McDermott MW, Sneed PK. Gamma knife radiosurgery for brainstem metastases: the UCSF experience. J Neurooncol. 2008 Jan; 86(2):195-205. PMID: 17628747.
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Nakamura J. The epidermal growth factor receptor in malignant gliomas: pathogenesis and therapeutic implications. Expert Opin Ther Targets. 2007 Apr; 11(4):463-72. PMID: 17373877.
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Panner A, Nakamura J, Parsa AT, Rodriguez-Viciana P, Berger MS, Stokoe D, Pieper RO. mTOR-independent translational control of the extrinsic cell death pathway by RalA. Mol Cell Biol. 2006 Oct; 26(20):7345-57. PMID: 16894031; PMCID: PMC1636864.
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Gottschalk AR, Doan A, Nakamura J, Stokoe D, Haas-Kogan DA. Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism. Int J Radiat Oncol Biol Phys. 2005 Nov 15; 63(4):1221-7. PMID: 16253776.
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Gottschalk AR, Doan A, Nakamura J, Haas-Kogan DA, Stokoe D. Inhibition of phosphatidylinositol-3-kinase causes cell death through a protein kinase B (PKB)-dependent mechanism and growth arrest through a PKB-independent mechanism. Int J Radiat Oncol Biol Phys. 2005 Mar 15; 61(4):1183-8. PMID: 15752900.
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Nakamura J, Karlsson A, Arvold ND, Gottschalk AR, Pieper RO, Stokoe D, Haas-Kogan DA. PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas. J Neurooncol. 2005 Feb; 71(3):215-22. PMID: 15735908.
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Nakamura J, Pirzkall A, Carol MP, Xia P, Smith V, Wara WM, Petti PL, Verhey LJ, Sneed PK. Comparison of intensity-modulated radiosurgery with gamma knife radiosurgery for challenging skull base lesions. Int J Radiat Oncol Biol Phys. 2003 Jan 01; 55(1):99-109. PMID: 12504041.
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Nakamura J, Verhey LJ, Smith V, Petti PL, Lamborn KR, Larson DA, Wara WM, McDermott MW, Sneed PK. Dose conformity of gamma knife radiosurgery and risk factors for complications. Int J Radiat Oncol Biol Phys. 2001 Dec 01; 51(5):1313-9. PMID: 11728692.
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