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Robert Hendren, DO

TitleProfessor
SchoolUCSF School of Medicine
DepartmentPsychiatry
Address401 Parnassus Ave, LangPorter
San Francisco CA 94143
Phone415-476-7044
EmailRobert.Hendren@ucsf.edu
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    Collapse Overview 
    Collapse Overview
    Robert L. Hendren, D.O., is Professor of Psychiatry and Behavioral Science; Division of Child and Adolescent Psychiatry; Co-Director of the UCSF Dyslexia Center; and Director, Neurodevelopmental, Translational Outcomes Research Program (NTORP). He works in the STAR Autism and Neurodevelopmental Disorders Program. Dr. Hendren is Past President of the American Academy of Child and Adolescent Psychiatry (2007-2009). He has published over 100 scientific papers and 5 books and has been listed in “The Best Doctors in America”, each year since it was first published in 1996.

    Dr. Hendren took his residency in general psychiatry at the Mayo Graduate School of Medicine, and his child and adolescent psychiatry fellowship at the Yale Child Study Center. He is board certified in General as well as Child and Adolescent Psychiatry. He has been on the faculty at the George Washington University School of Medicine, the University of New Mexico School of Medicine, and the University of Medicine and Dentistry of New Jersey (now Rutger’s) - Robert Wood Johnson and New Jersey Medical Schools. From 2001-2009, he was Professor of Psychiatry and Executive Director and Tsakopoulos-Vismara Chair at the University of California, Davis M.I.N.D. Institute (Medical Investigation of Neurodevelopmental Disorders).

    His current areas of research and publication interests are translational interventional outcomes research including clinical pharmacology, nutraceutical and nutritional trials using biomarkers (MRI, measures of inflammation, oxidative stress, immune function and pharmacogenomics) to enhance resilience in neurodevelopmental disorders. He is currently applying a targeted outcomes research approach in a collaborative projects with the Oak Hill School for youth with severe autism and neurodevelopmental spectrum disorders in San Anselmo, CA and at the Charles Armstrong School for youth with dyslexia in Belmont, CA.


    Collapse Research 
    Collapse Research Activities and Funding
    Pharmacogenomics in Autism Treatment
    NIH/NIMH R21MH080026Feb 1, 2008 - Jan 31, 2011
    Role: Principal Investigator
    NEUROPSYCHOPHYSIOLOGIC STUDY-SEVERELY DISTURBED CHILDREN
    NIH/NIMH R01MH045838Apr 1, 1991 - Mar 31, 1995
    Role: Principal Investigator

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    Collapse Clinical Trials
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Dang K, Bent S, Lawton B, Warren T, Widjaja F, McDonald MG, Breard M, O'Keefe W, Hendren RL. Integrating Autism Care through a School-Based Intervention Model: A Pilot Study. J Clin Med. 2017 Oct 19; 6(10). PMID: 29048365.
      View in: PubMed
    2. Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Hertz-Picciotto I, Fallin MD, Weiss LA. Correction: Pleiotropic Mechanisms Indicated for Sex Differences in Autism. PLoS Genet. 2017 Jun; 13(6):e1006831. PMID: 28591140.
      View in: PubMed
    3. Bangerter A, Ness S, Aman MG, Esbensen AJ, Goodwin MS, Dawson G, Hendren R, Leventhal B, Khan A, Opler M, Harris A, Pandina G. Autism Behavior Inventory: A Novel Tool for Assessing Core and Associated Symptoms of Autism Spectrum Disorder. J Child Adolesc Psychopharmacol. 2017 May 12. PMID: 28498053.
      View in: PubMed
    4. Bent S, Dang K, Widjaja F, Lawton B, Hendren RL. Examining Clinics for Children with Autism: The Autism Translating To Treatment Study. J Altern Complement Med. 2017 May; 23(5):340-347. PMID: 28084799.
      View in: PubMed
    5. Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Herz-Picciotto I, Fallin MD, Weiss LA. Pleiotropic Mechanisms Indicated for Sex Differences in Autism. PLoS Genet. 2016 11; 12(11):e1006425. PMID: 27846226.
      View in: PubMed
    6. Hendren RL, James SJ, Widjaja F, Lawton B, Rosenblatt A, Bent S. Randomized, Placebo-Controlled Trial of Methyl B12 for Children with Autism. J Child Adolesc Psychopharmacol. 2016 Nov; 26(9):774-783. PMID: 26889605.
      View in: PubMed
    7. Besterman AD, Hendren RL. Psychopharmacological Management of Problem Behaviors in Mowat-Wilson Syndrome. J Child Adolesc Psychopharmacol. 2015 Oct; 25(8):656-7. PMID: 26402313; PMCID: PMC4615772 [Available on 10/01/16].
    8. Bent S, Hendren RL. Complementary and alternative treatments for autism part 1: evidence-supported treatments. AMA J Ethics. 2015 Apr 01; 17(4):369-74. PMID: 25901707.
      View in: PubMed
    9. Choi JE, Widjaja F, Careaga M, Bent S, Ashwood P, Hendren RL. Change in plasma cytokine levels during risperidone treatment in children with autism. J Child Adolesc Psychopharmacol. 2014 Dec; 24(10):586-9. PMID: 24828014; PMCID: PMC4268580.
    10. Burton B, Grant M, Feigenbaum A, Singh R, Hendren R, Siriwardena K, Phillips J, Sanchez-Valle A, Waisbren S, Gillis J, Prasad S, Merilainen M, Lang W, Zhang C, Yu S, Stahl S. A randomized, placebo-controlled, double-blind study of sapropterin to treat ADHD symptoms and executive function impairment in children and adults with sapropterin-responsive phenylketonuria. Mol Genet Metab. 2015 Mar; 114(3):415-24. PMID: 25533024.
      View in: PubMed
    11. Myers CA, Vandermosten M, Farris EA, Hancock R, Gimenez P, Black JM, Casto B, Drahos M, Tumber M, Hendren RL, Hulme C, Hoeft F. White matter morphometric changes uniquely predict children's reading acquisition. Psychol Sci. 2014 Oct; 25(10):1870-83. PMID: 25212581; PMCID: PMC4326021.
    12. Goldani AA, Downs SR, Widjaja F, Lawton B, Hendren RL. Biomarkers in autism. Front Psychiatry. 2014; 5:100. PMID: 25161627; PMCID: PMC4129499.
    13. Gimenez P, Bugescu N, Black JM, Hancock R, Pugh K, Nagamine M, Kutner E, Mazaika P, Hendren R, McCandliss BD, Hoeft F. Neuroimaging correlates of handwriting quality as children learn to read and write. Front Hum Neurosci. 2014; 8:155. PMID: 24678293; PMCID: PMC3958698.
    14. Bent S, Hendren RL, Zandi T, Law K, Choi JE, Widjaja F, Kalb L, Nestle J, Law P. Internet-based, randomized, controlled trial of omega-3 fatty acids for hyperactivity in autism. J Am Acad Child Adolesc Psychiatry. 2014 Jun; 53(6):658-66. PMID: 24839884; PMCID: PMC4076340.
    15. Adviento B, Corbin IL, Widjaja F, Desachy G, Enrique N, Rosser T, Risi S, Marco EJ, Hendren RL, Bearden CE, Rauen KA, Weiss LA. Autism traits in the RASopathies. J Med Genet. 2014 Jan; 51(1):10-20. PMID: 24101678; PMCID: PMC4230531.
    16. McBurnett K, Swetye M, Muhr H, Hendren RL. Pharmacotherapy of inattention and ADHD in adolescents. Adolesc Med State Art Rev. 2013 Aug; 24(2):391-405, viii. PMID: 24298754.
      View in: PubMed
    17. Cheng JX, Widjaja F, Choi JE, Hendren RL. Considering biomedical/CAM treatments. Adolesc Med State Art Rev. 2013 Aug; 24(2):446-64, x. PMID: 24298758.
      View in: PubMed
    18. Hendren RL, Reeve A. Preface. Adolescent psychopharmacology update. Adolesc Med State Art Rev. 2013 Aug; 24(2):xi-xiii. PMID: 24298751.
      View in: PubMed
    19. Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT. Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents. Biol Psychiatry. 2013 Dec 15; 74(12):898-907. PMID: 23910949; PMCID: PMC4103629.
    20. Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT. Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression. J Am Acad Child Adolesc Psychiatry. 2013 Oct; 52(10):1076-1091.e2. PMID: 24074474; PMCID: PMC3825460.
    21. Hendren RL. Autism: biomedical complementary treatment approaches. Child Adolesc Psychiatr Clin N Am. 2013 Jul; 22(3):443-56, vi. PMID: 23806313.
      View in: PubMed
    22. Xie Y, Dixon JF, Yee OM, Zhang J, Chen YA, Deangelo S, Yellowlees P, Hendren R, Schweitzer JB. A study on the effectiveness of videoconferencing on teaching parent training skills to parents of children with ADHD. Telemed J E Health. 2013 Mar; 19(3):192-9. PMID: 23405952.
      View in: PubMed
    23. Lofthouse N, Hendren R, Hurt E, Arnold LE, Butter E. A review of complementary and alternative treatments for autism spectrum disorders. Autism Res Treat. 2012; 2012:870391. PMID: 23243505; PMCID: PMC3515887.
    24. Bent S, Bertoglio K, Ashwood P, Nemeth E, Hendren RL. Brief report: Hyperbaric oxygen therapy (HBOT) in children with autism spectrum disorder: a clinical trial. J Autism Dev Disord. 2012 Jun; 42(6):1127-32. PMID: 21818676.
      View in: PubMed
    25. Lit L, Sharp FR, Bertoglio K, Stamova B, Ander BP, Sossong AD, Hendren RL. Gene expression in blood is associated with risperidone response in children with autism spectrum disorders. Pharmacogenomics J. 2012 Oct; 12(5):368-71. PMID: 21647175; PMCID: PMC3175502.
    26. Bent S, Bertoglio K, Ashwood P, Bostrom A, Hendren RL. A pilot randomized controlled trial of omega-3 fatty acids for autism spectrum disorder. J Autism Dev Disord. 2011 May; 41(5):545-54. PMID: 20683766; PMCID: PMC3076562.
    27. Hagerman RJ, Hendren RL. Shifting the paradigm for autism treatments. Neurotherapeutics. 2010 Jul; 7(3):230-1. PMID: 20643374; PMCID: PMC4043294.
    28. Bent S, Hendren RL. Improving the prediction of response to therapy in autism. Neurotherapeutics. 2010 Jul; 7(3):232-40. PMID: 20643375.
      View in: PubMed
    29. Bertoglio K, Jill James S, Deprey L, Brule N, Hendren RL. Pilot study of the effect of methyl B12 treatment on behavioral and biomarker measures in children with autism. J Altern Complement Med. 2010 May; 16(5):555-60. PMID: 20804367.
      View in: PubMed
    30. Stoddard J, Niendam T, Hendren R, Carter C, Simon TJ. Attenuated positive symptoms of psychosis in adolescents with chromosome 22q11.2 deletion syndrome. Schizophr Res. 2010 May; 118(1-3):118-21. PMID: 20056393; PMCID: PMC2856801.
    31. Hendren RL, Bertoglio K, Ashwood P, Sharp F. Mechanistic biomarkers for autism treatment. Med Hypotheses. 2009 Dec; 73(6):950-4. PMID: 19619951.
      View in: PubMed
    32. Hilty DM, Yellowlees PM, Sonik P, Derlet M, Hendren RL. Rural child and adolescent telepsychiatry: successes and struggles. Pediatr Ann. 2009 Apr; 38(4):228-32. PMID: 19455953.
      View in: PubMed
    33. Bent S, Bertoglio K, Hendren RL. Omega-3 fatty acids for autistic spectrum disorder: a systematic review. J Autism Dev Disord. 2009 Aug; 39(8):1145-54. PMID: 19333748; PMCID: PMC2710498.
    34. Corbett BA, Constantine LJ, Hendren R, Rocke D, Ozonoff S. Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development. Psychiatry Res. 2009 Apr 30; 166(2-3):210-22. PMID: 19285351; PMCID: PMC2683039.
    35. Bertoglio K, Hendren RL. New developments in autism. Psychiatr Clin North Am. 2009 Mar; 32(1):1-14. PMID: 19248913.
      View in: PubMed
    36. Solomon M, Hessl D, Chiu S, Olsen E, Hendren RL. Towards a neurodevelopmental model of clinical case formulation. Psychiatr Clin North Am. 2009 Mar; 32(1):199-211. PMID: 19248925; PMCID: PMC2692218.
    37. McCarthy M, Hendren RL. Autism spectrum disorders have increased dramatically in prevalence in recent years. Preface. Psychiatr Clin North Am. 2009 Mar; 32(1):xiii-xv. PMID: 19248912.
      View in: PubMed
    38. Bent S, Bertoglio K, Hendren RL. Regarding omega-3 fatty acids in severe autism. Arch Med Res. 2009 Jan; 40(1):64; author reply 65. PMID: 19064131.
      View in: PubMed
    39. Martin A, Hendren RL, Greenhill LL, Bird HR. Hats off: journal awards. J Am Acad Child Adolesc Psychiatry. 2008 Dec; 47(12):1484-5. PMID: 19034192.
      View in: PubMed
    40. Hendren RL. Casting a wide net to nurture mentally healthy children. J Am Acad Child Adolesc Psychiatry. 2008 Feb; 47(2):123-8. PMID: 18216713.
      View in: PubMed
    41. Chiu S, Widjaja F, Bates ME, Voelbel GT, Pandina G, Marble J, Blank JA, Day J, Brule N, Hendren RL. Anterior cingulate volume in pediatric bipolar disorder and autism. J Affect Disord. 2008 Jan; 105(1-3):93-9. PMID: 17568686.
      View in: PubMed
    42. Sharp FR, Hendren RL. Psychosis: atypical limbic epilepsy versus limbic hyperexcitability with onset at puberty? Epilepsy Behav. 2007 Jun; 10(4):515-20. PMID: 17416210; PMCID: PMC2680611.
    43. Solomon M, Hessl D, Chiu S, Hagerman R, Hendren R. A genetic etiology of pervasive developmental disorder guides treatment. Am J Psychiatry. 2007 Apr; 164(4):575-80. PMID: 17403969.
      View in: PubMed
    44. Voelbel GT, Bates ME, Buckman JF, Pandina G, Hendren RL. Caudate nucleus volume and cognitive performance: Are they related in childhood psychopathology? Biol Psychiatry. 2006 Nov 01; 60(9):942-50. PMID: 16950212; PMCID: PMC2947855.
    45. Sugden SG, Kile SJ, Hendren RL. Neurodevelopmental pathways to aggression: a model to understand and target treatment in youth. J Neuropsychiatry Clin Neurosci. 2006; 18(3):302-17. PMID: 16963580.
      View in: PubMed
    46. Hendren RL. Discussion on integrated pharmacologic treatment of attention-deficit hyperactivity disorder (ADHD). Essent Psychopharmacol. 2005; 6(5):291-300. PMID: 16222913.
      View in: PubMed
    47. Horst RO, Hendren RL. Integrated pharmacologic treatment of attention-deficit hyperactivity disorder (ADHD). Essent Psychopharmacol. 2005; 6(5):250-61. PMID: 16222910.
      View in: PubMed
    48. Hanft A, Hendren RL. Pharmacotherapy of children and adolescents with pervasive developmental disorders. Essent Psychopharmacol. 2004; 6(1):12-24. PMID: 15612651.
      View in: PubMed
    49. Hendren RL, De Backer I, Pandina GJ. Review of neuroimaging studies of child and adolescent psychiatric disorders from the past 10 years. J Am Acad Child Adolesc Psychiatry. 2000 Jul; 39(7):815-28. PMID: 10892223.
      View in: PubMed
    50. Brooks WM, Hodde-Vargas J, Vargas LA, Yeo RA, Ford CC, Hendren RL. Frontal lobe of children with schizophrenia spectrum disorders: a proton magnetic resonance spectroscopic study. Biol Psychiatry. 1998 Feb 15; 43(4):263-9. PMID: 9513735.
      View in: PubMed
    51. Yeo RA, Hodde-Vargas J, Hendren RL, Vargas LA, Brooks WM, Ford CC, Gangestad SW, Hart BL. Brain abnormalities in schizophrenia-spectrum children: implications for a neurodevelopmental perspective. Psychiatry Res. 1997 Nov 28; 76(1):1-13. PMID: 9498305.
      View in: PubMed
    52. Bailey RA, Hendren RL. A Primer on Adolescent Psychopharmacology. Adolesc Med. 1997 Feb; 8(1):33-55. PMID: 10360007.
      View in: PubMed
    53. Hendren RL, Hodde-Vargas J, Yeo RA, Vargas LA, Brooks WM, Ford C. Neuropsychophysiological study of children at risk for schizophrenia: a preliminary report. J Am Acad Child Adolesc Psychiatry. 1995 Oct; 34(10):1284-91. PMID: 7592265.
      View in: PubMed
    54. Strasburger VC, Hendren RL. Rock music and music videos. Pediatr Ann. 1995 Feb; 24(2):97-103. PMID: 7724257.
      View in: PubMed
    55. Hendren RL. Adolescent psychotherapy research: a practical review. Am J Psychother. 1993; 47(3):334-43. PMID: 8214212.
      View in: PubMed
    56. Geraty RD, Hendren RL, Flaa CJ. Ethical perspectives on managed care as it relates to child and adolescent psychiatry. J Am Acad Child Adolesc Psychiatry. 1992 May; 31(3):398-402. PMID: 1592769.
      View in: PubMed
    57. Davis G, Hendren RL. What Pediatricians Should Know About Adolescent Psychiatry. Adolesc Med. 1992 Feb; 3(1):131-146. PMID: 10356171.
      View in: PubMed
    58. Hendren RL. Brain imaging and neurodevelopmental psychiatry. West J Med. 1991 Nov; 155(5):522-3. PMID: 1815401; PMCID: PMC1003075.
    59. Hendren RL, Hodde-Vargas JE, Vargas LA, Orrison WW, Dell L. Magnetic resonance imaging of severely disturbed children--a preliminary study. J Am Acad Child Adolesc Psychiatry. 1991 May; 30(3):466-70. PMID: 2055885.
      View in: PubMed
    60. Hendren RL, Taylor WS, Lemke BJ, Lemke PA. An autistic boy copes with a terminal illness. J Am Acad Child Adolesc Psychiatry. 1990 Nov; 29(6):901-4. PMID: 2273018.
      View in: PubMed
    61. Hendren RL, Sholevar GP, Weinberger DR, Wiener JM. Schizophrenia in a fourteen-year-old boy. J Am Acad Child Adolesc Psychiatry. 1990 Jan; 29(1):141-8. PMID: 2295568.
      View in: PubMed
    62. Hendren RL. Predicting success and failure of medical students at risk for dismissal. J Med Educ. 1988 Aug; 63(8):596-602. PMID: 3398014.
      View in: PubMed
    63. Hendren RL, Atkins DM, Sumner CR, Barber JK. Model for the group treatment of eating disorders. Int J Group Psychother. 1987 Oct; 37(4):589-602. PMID: 3679642.
      View in: PubMed
    64. Hendren RL, Barber JK, Sigafoos A. Eating-disordered symptoms in a nonclinical population: a study of female adolescents in two private schools. J Am Acad Child Psychiatry. 1986 Nov; 25(6):836-40. PMID: 3794126.
      View in: PubMed
    65. Wiener JM, Hendren RL. Childhood depression. J Dev Behav Pediatr. 1983 Mar; 4(1):43-9. PMID: 6833504.
      View in: PubMed
    66. Hendren RL. Depression in anorexia nervosa. J Am Acad Child Psychiatry. 1983 Jan; 22(1):59-62. PMID: 6826999.
      View in: PubMed
    67. Kuhnley EJ, Hendren RL, Quinlan DM. Fire-setting by children. J Am Acad Child Psychiatry. 1982 Nov; 21(6):560-3. PMID: 7175051.
      View in: PubMed
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