Lauren Weiss, PhD

Title(s)Professor, Psychiatry
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSE, #901C
San Francisco CA 94143
Phone415-476-7650
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Overview 
    Collapse Overview
    My laboratory focuses on understanding the genetic architecture of autism. We are working with genome-wide genetic data to identify additional susceptibility loci, the genetic mechanisms by which DNA variants influence autism risk, and the genetic and physiological pathways these risk loci implicate. We can use rich genetic datasets to ask questions about the role for copy number vs. SNP variation, rare vs. common variation, gene-sex interaction, gene-gene interaction, and gene-environment interaction.


    We are also using human induced pluripotent stem cell (iPSC) models to study known mutations or copy number variants predisposing to autism. We will first identify the effects of genetic risk variants and then be able to ascertain whether the effects of genetic risk can be modified at the cellular level by environmental or pharmacological agents. These models will be used to test hypotheses emerging from our genetic datasets.


    Our long term goals are to use genetic tools to improve understanding, prevention, diagnosis, and treatment of autism and related traits.

    Collapse Research 
    Collapse Research Activities and Funding
    Decoding the Genetics of Sexual Dimorphism in Autism Spectrum Disorders
    NIH R01MH114924Sep 13, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Utilizing eQTL networks to gain biological insight into multigenic CNVs
    NIH R01MH107467Apr 1, 2016 - Feb 28, 2021
    Role: Principal Investigator
    Epigenetic loss of heterozygosity in a recurrent neurodevelopmental CNV region
    NIH R21MH105745Sep 5, 2014 - Aug 31, 2017
    Role: Co-Principal Investigator
    Dissecting Epistasis and Pleiotropy in Autism towards Personalized Medicine
    NIH DP2OD007449Sep 30, 2010 - Jun 30, 2015
    Role: Principal Investigator
    A Sex-Specific Dissection of Autism Genetics
    NIH R21HD065273Sep 30, 2009 - Aug 31, 2012
    Role: Principal Investigator
    Molecular analysis of a gene affecting social cognition
    NIH F32MH077476May 7, 2007 - Apr 30, 2008
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Examining Sex Differences in Autism Heritability. JAMA Psychiatry. 2024 Apr 17. Sandin S, Yip BHK, Yin W, Weiss LA, Dougherty JD, Fass S, Constantino JN, Hailin Z, Turner TN, Marrus N, Gutmann DH, Sanders SJ, Christoffersson B. PMID: 38630491; PMCID: PMC11024771.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Inflammatory Conditions During Pregnancy and Risk of Autism and Other Neurodevelopmental Disorders. Biol Psychiatry Glob Open Sci. 2024 Jan; 4(1):39-50. Croen LA, Ames JL, Qian Y, Alexeeff S, Ashwood P, Gunderson EP, Wu YW, Boghossian AS, Yolken R, Van de Water J, Weiss LA. PMID: 38045769; PMCID: PMC10689278.
      View in: PubMed   Mentions: 2  
    3. Combinations of genes at the 16p11.2 and 22q11.2 CNVs contribute to neurobehavioral traits. PLoS Genet. 2023 06; 19(6):e1010780. Vysotskiy M, Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Weiss LA. PMID: 37267418; PMCID: PMC10266672.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Relationships between levels of endocrine-disrupting chemicals and immune markers in maternal circulation during mid-pregnancy. ISEE Conference Abstracts. 2022 Sep 18; 2022(1). Ames AJ, Alexeeff AS, Ashwood AP, Berger BK, Hamra HG, Kharrazi KM, Lyall LK, Van de Water VJ, Volk VH, Weiss WL, Windham WG, Yolken YR, Yoshida YC, Croen CL. .
      View in: Publisher Site   Mentions:
    5. Can the "female protective effect" liability threshold model explain sex differences in autism spectrum disorder? Neuron. 2022 10 19; 110(20):3243-3262. Dougherty JD, Marrus N, Maloney SE, Yip B, Sandin S, Turner TN, Selmanovic D, Kroll KL, Gutmann DH, Constantino JN, Weiss LA. PMID: 35868305; PMCID: PMC9588569.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    6. Sex-heterogeneous SNPs disproportionately influence gene expression and health. PLoS Genet. 2022 05; 18(5):e1010147. Traglia M, Bout M, Weiss LA. PMID: 35511767; PMCID: PMC9070888.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes. Genome Med. 2021 10 29; 13(1):172. Vysotskiy M, Zhong X, Miller-Fleming TW, Zhou D, Autism Working Group of the Psychiatric Genomics Consortium^, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium^, Schizophrenia Working Group of the Psychiatric Genomics Consortium^, Cox NJ, Weiss LA. PMID: 34715901; PMCID: PMC8557010.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    8. A profile and review of findings from the Early Markers for Autism study: unique contributions from a population-based case-control study in California. Mol Autism. 2021 03 18; 12(1):24. Lyall K, Ames JL, Pearl M, Traglia M, Weiss LA, Windham GC, Kharrazi M, Yoshida CK, Yolken R, Volk HE, Ashwood P, Van de Water J, Croen LA. PMID: 33736683; PMCID: PMC7977191.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    9. Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits. Biol Psychiatry. 2021 06 15; 89(12):1127-1137. Martin J, Khramtsova EA, Goleva SB, Blokland GAM, Traglia M, Walters RK, Hübel C, Coleman JRI, Breen G, Børglum AD, Demontis D, Grove J, Werge T, Bralten J, Bulik CM, Lee PH, Mathews CA, Peterson RE, Winham SJ, Wray N, Edenberg HJ, Guo W, Yao Y, Neale BM, Faraone SV, Petryshen TL, Weiss LA, Duncan LE, Goldstein JM, Smoller JW, Stranger BE, Davis LK, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium. PMID: 33648717; PMCID: PMC8163257.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    10. Publisher Correction: Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nat Neurosci. 2020 Sep; 23(9):1176. Lim ET, Uddin M, De Rubeis S, Chan Y, Kamumbu AS, Zhang X, D'Gama AM, Kim SN, Hill RS, Goldberg AP, Poultney C, Minshew NJ, Kushima I, Aleksic B, Ozaki N, Parellada M, Arango C, Penzol MJ, Carracedo A, Kolevzon A, Hultman CM, Weiss LA, Fromer M, Chiocchetti AG, Freitag CM, Autism Sequencing Consortium, Church GM, Scherer SW, Buxbaum JD, Walsh CA. PMID: 32665711.
      View in: PubMed   Mentions:    Fields:    
    11. Autism in neurofibromatosis type 1: misuse of covariance to dismiss autistic trait burden. Dev Med Child Neurol. 2021 02; 63(2):233-234. Morris SM, Acosta MT, Garg S, Green J, Legius E, North K, Payne JM, Weiss LA, Constantino JN, Gutmann DH. PMID: 32815557.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Genetic Contributions to Maternal and Neonatal Vitamin D Levels. Genetics. 2020 04; 214(4):1091-1102. Traglia M, Windham GC, Pearl M, Poon V, Eyles D, Jones KL, Lyall K, Kharrazi M, Croen LA, Weiss LA. PMID: 32047095; PMCID: PMC7153928.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    13. Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes. Nat Genet. 2019 08; 51(8):1252-1262. Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M, Tam TW, Jamieson K, Lu SY, Ming GL, Li Y, Yao J, Weiss LA, Dixon JR, Judge LM, Conklin BR, Song H, Gan L, Shen Y. PMID: 31367015; PMCID: PMC6677164.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    14. cis-Regulatory Chromatin Contacts in Neural Cells Reveal Contributions of Genetic Variants to Complex Neurological Disorders. bioRxiv. 2018 Dec 13; 494450. Song SM, Yang YX, Ren RX, Maliskova ML, Li LB, Jones JI, Wang WC, Jacob JF, Wu WK, Traglia TM, Tam TT, Jamieson JK, Lu LS, Ming MG, Yao YJ, Weiss WL, Dixon DJ, Judge JL, Conklin CB, Song SH, Gan GL, Shen SY. .
      View in: Publisher Site   Mentions:
    15. Cross-genetic determination of maternal and neonatal immune mediators during pregnancy. Genome Med. 2018 08 22; 10(1):67. Traglia M, Croen LA, Jones KL, Heuer LS, Yolken R, Kharrazi M, DeLorenze GN, Ashwood P, Van de Water J, Weiss LA. PMID: 30134952; PMCID: PMC6106874.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    16. Analysis of shared heritability in common disorders of the brain. Science. 2018 06 22; 360(6395). Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono RJ, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, et al. PMID: 29930110; PMCID: PMC6097237.
      View in: PubMed   Mentions: 698     Fields:    Translation:Humans
    17. RASopathies are associated with a distinct personality profile. Am J Med Genet B Neuropsychiatr Genet. 2018 06; 177(4):434-446. Bizaoui V, Gage J, Brar R, Rauen KA, Weiss LA. PMID: 29659143; PMCID: PMC6039190.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    18. Age and ASD symptoms in Costello syndrome. Am J Med Genet A. 2018 04; 176(4):1027-1028. Young O, Perati S, Weiss LA, Rauen KA. PMID: 29575620; PMCID: PMC6011828.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Recurrent reciprocal copy number variants: Roles and rules in neurodevelopmental disorders. Dev Neurobiol. 2018 May; 78(5):519-530. Deshpande A, Weiss LA. PMID: 29575775.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    20. Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. Cell Rep. 2017 Dec 05; 21(10):2678-2687. Deshpande A, Yadav S, Dao DQ, Wu ZY, Hokanson KC, Cahill MK, Wiita AP, Jan YN, Ullian EM, Weiss LA. PMID: 29212016; PMCID: PMC5730067.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    21. Prenatal Serum Concentrations of Brominated Flame Retardants and Autism Spectrum Disorder and Intellectual Disability in the Early Markers of Autism Study: A Population-Based Case-Control Study in California. Environ Health Perspect. 2017 08 30; 125(8):087023. Lyall K, Croen LA, Weiss LA, Kharrazi M, Traglia M, Delorenze GN, Windham GC. PMID: 28895873; PMCID: PMC5783661.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    22. Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nat Neurosci. 2017 09; 20(9):1217-1224. Lim ET, Uddin M, De Rubeis S, Chan Y, Kamumbu AS, Zhang X, D'Gama AM, Kim SN, Hill RS, Goldberg AP, Poultney C, Minshew NJ, Kushima I, Aleksic B, Ozaki N, Parellada M, Arango C, Penzol MJ, Carracedo A, Kolevzon A, Hultman CM, Weiss LA, Fromer M, Chiocchetti AG, Freitag CM, Autism Sequencing Consortium, Church GM, Scherer SW, Buxbaum JD, Walsh CA. PMID: 28714951; PMCID: PMC5672813.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansCells
    23. Correction: Pleiotropic Mechanisms Indicated for Sex Differences in Autism. PLoS Genet. 2017 Jun; 13(6):e1006831. Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Hertz-Picciotto I, Fallin MD, Weiss LA. PMID: 28591140; PMCID: PMC5462340.
      View in: PubMed   Mentions: 1     Fields:    
    24. Most Frequently Reported Prescription Medications and Supplements in Couples Planning Pregnancy: The LIFE Study. Reprod Sci. 2018 01; 25(1):94-101. Palmsten K, Flores KF, Chambers CD, Weiss LA, Sundaram R, Buck Louis GM. PMID: 28401798; PMCID: PMC5993075.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    25. Independent Maternal and Fetal Genetic Effects on Midgestational Circulating Levels of Environmental Pollutants. G3 (Bethesda). 2017 04 03; 7(4):1287-1299. Traglia M, Croen LA, Lyall K, Windham GC, Kharrazi M, DeLorenze GN, Torres AR, Weiss LA. PMID: 28235828; PMCID: PMC5386877.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    26. Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders. PLoS Genet. 2017 Jan; 13(1):e1006516. Mitra I, Lavillaureix A, Yeh E, Traglia M, Tsang K, Bearden CE, Rauen KA, Weiss LA. PMID: 28076348; PMCID: PMC5226683.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    27. Genetic Mechanisms Leading to Sex Differences Across Common Diseases and Anthropometric Traits. Genetics. 2017 02; 205(2):979-992. Traglia M, Bseiso D, Gusev A, Adviento B, Park DS, Mefford JA, Zaitlen N, Weiss LA. PMID: 27974502; PMCID: PMC5289864.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    28. Disease Burden and Symptom Structure of Autism in Neurofibromatosis Type 1: A Study of the International NF1-ASD Consortium Team (INFACT). JAMA Psychiatry. 2016 Dec 01; 73(12):1276-1284. Morris SM, Acosta MT, Garg S, Green J, Huson S, Legius E, North KN, Payne JM, Plasschaert E, Frazier TW, Weiss LA, Zhang Y, Gutmann DH, Constantino JN. PMID: 27760236; PMCID: PMC5298203.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    29. Pleiotropic Mechanisms Indicated for Sex Differences in Autism. PLoS Genet. 2016 11; 12(11):e1006425. Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Hertz-Picciotto I, Fallin MD, Weiss LA. PMID: 27846226; PMCID: PMC5147776.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    30. If genetic variation could talk: What genomic data may teach us about the importance of gene expression regulation in the genetics of autism. Mol Cell Probes. 2016 12; 30(6):346-356. Yeh E, Weiss LA. PMID: 27751841.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    31. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports. 2016 09 13; 7(3):355-369. Josowitz R, Mulero-Navarro S, Rodriguez NA, Falce C, Cohen N, Ullian EM, Weiss LA, Rauen KA, Sobie EA, Gelb BD. PMID: 27569062; PMCID: PMC5032183.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    32. Prenatal levels of Polybrominated Diphenyl Ethers (PBDEs) in association with Autism Spectrum Disorder. ISEE Conference Abstracts. 2016 Aug 17; 2016(1). Windham* WG, Lyall LK, Kharrazi KM, Weiss WL, Croen CL. .
      View in: Publisher Site   Mentions:
    33. Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. J Neurosci. 2016 Jan 06; 36(1):142-52. Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM. PMID: 26740656; PMCID: PMC4701956.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    34. Dysregulation of astrocyte extracellular signaling in Costello syndrome. Sci Transl Med. 2015 May 06; 7(286):286ra66. Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney GE, Rauen KA, Weiss LA, Rowitch DH, Ullian EM. PMID: 25947161; PMCID: PMC4474402.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    35. Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. Am J Hum Genet. 2015 Feb 05; 96(2):283-94. Maier R, Moser G, Chen GB, Ripke S, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Coryell W, Potash JB, Scheftner WA, Shi J, Weissman MM, Hultman CM, Landén M, Levinson DF, Kendler KS, Smoller JW, Wray NR, Lee SH. PMID: 25640677; PMCID: PMC4320268.
      View in: PubMed   Mentions: 127     Fields:    Translation:Humans
    36. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci. 2015 Feb; 18(2):199-209. Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium. PMID: 25599223; PMCID: PMC4378867.
      View in: PubMed   Mentions: 382     Fields:    Translation:HumansCells
    37. Increased female autosomal burden of rare copy number variants in human populations and in autism families. Mol Psychiatry. 2015 Feb; 20(2):170-5. Desachy G, Croen LA, Torres AR, Kharrazi M, Delorenze GN, Windham GC, Yoshida CK, Weiss LA. PMID: 25582617.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    38. Abstract 19583: Autonomous and Non-Autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Circulation. 2014 Nov 25; 130(suppl_2). Josowitz JR, Mulero-Navarro MS, Falce FC, Cohen CN, Ullian UE, Weiss WL, Rauen RK, Sobie SE, Gelb GB. .
      View in: Publisher Site   Mentions:
    39. Synaptic, transcriptional and chromatin genes disrupted in autism. Nature. 2014 Nov 13; 515(7526):209-15. De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Cicek AE, Kou Y, Liu L, Fromer M, Walker S, Singh T, Klei L, Kosmicki J, Shih-Chen F, Aleksic B, Biscaldi M, Bolton PF, Brownfeld JM, Cai J, Campbell NG, Carracedo A, Chahrour MH, Chiocchetti AG, Coon H, Crawford EL, Curran SR, Dawson G, Duketis E, Fernandez BA, Gallagher L, Geller E, Guter SJ, Hill RS, Ionita-Laza J, Jimenz Gonzalez P, Kilpinen H, Klauck SM, Kolevzon A, Lee I, Lei I, Lei J, Lehtimäki T, Lin CF, Ma'ayan A, Marshall CR, McInnes AL, Neale B, Owen MJ, Ozaki N, Parellada M, Parr JR, Purcell S, Puura K, Rajagopalan D, Rehnström K, Reichenberg A, Sabo A, Sachse M, Sanders SJ, Schafer C, Schulte-Rüther M, Skuse D, Stevens C, Szatmari P, Tammimies K, Valladares O, Voran A, Li-San W, Weiss LA, Willsey AJ, Yu TW, Yuen RK, DDD Study, Homozygosity Mapping Collaborative for Autism, UK10K Consortium, Cook EH, Freitag CM, Gill M, Hultman CM, Lehner T, Palotie A, Schellenberg GD, Sklar P, State MW, Sutcliffe JS, Walsh CA, Scherer SW, Zwick ME, Barett JC, Cutler DJ, Roeder K, Devlin B, Daly MJ, Buxbaum JD. PMID: 25363760; PMCID: PMC4402723.
      View in: PubMed   Mentions: 1326     Fields:    Translation:HumansCells
    40. Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature. 2014 Mar 06; 507(7490):99-103. Bershteyn M, Hayashi Y, Desachy G, Hsiao EC, Sami S, Tsang KM, Weiss LA, Kriegstein AR, Yamanaka S, Wynshaw-Boris A. PMID: 24413397; PMCID: PMC4030630.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    41. A genome-wide survey of transgenerational genetic effects in autism. PLoS One. 2013; 8(10):e76978. Tsang KM, Croen LA, Torres AR, Kharrazi M, Delorenze GN, Windham GC, Yoshida CK, Zerbo O, Weiss LA. PMID: 24204716; PMCID: PMC3811986.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    42. Autism traits in the RASopathies. J Med Genet. 2014 Jan; 51(1):10-20. Adviento B, Corbin IL, Widjaja F, Desachy G, Enrique N, Rosser T, Risi S, Marco EJ, Hendren RL, Bearden CE, Rauen KA, Weiss LA. PMID: 24101678; PMCID: PMC4230531.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    43. SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs). Mol Autism. 2013 Oct 03; 4(1):36. Abrahams BS, Arking DE, Campbell DB, Mefford HC, Morrow EM, Weiss LA, Menashe I, Wadkins T, Banerjee-Basu S, Packer A. PMID: 24090431; PMCID: PMC3851189.
      View in: PubMed   Mentions: 360     Fields:    
    44. An eQTL mapping approach reveals that rare variants in the SEMA5A regulatory network impact autism risk. Hum Mol Genet. 2013 Jul 15; 22(14):2960-72. Cheng Y, Quinn JF, Weiss LA. PMID: 23575222; PMCID: PMC3690972.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    45. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet. 2012; 8(3):e1002592. Chow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork NJ, Courchesne E. PMID: 22457638; PMCID: PMC3310790.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    46. Autism genetics: emerging data from genome-wide copy-number and single nucleotide polymorphism scans. Expert Rev Mol Diagn. 2009 Nov; 9(8):795-803. Weiss LA. PMID: 19895225.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    47. A genome-wide linkage and association scan reveals novel loci for autism. Nature. 2009 Oct 08; 461(7265):802-8. Weiss LA, Arking DE, Gene Discovery Project of Johns Hopkins & the Autism Consortium, Daly MJ, Chakravarti A. PMID: 19812673; PMCID: PMC2772655.
      View in: PubMed   Mentions: 306     Fields:    Translation:HumansCells
    48. New insights into genomic variation in health and disease. Genome Med. 2009 Apr 22; 1(4):41. Weiss LA. PMID: 19435489; PMCID: PMC2684662.
      View in: PubMed   Mentions:    Fields:    
    49. Preliminary evidence of association between EFHC2, a gene implicated in fear recognition, and harm avoidance. Neurosci Lett. 2009 Mar 06; 452(1):84-6. Blaya C, Moorjani P, Salum GA, Gonçalves L, Weiss LA, Leistner-Segal S, Manfro GG, Smoller JW. PMID: 19429002.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    50. Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders. J Med Genet. 2009 Apr; 46(4):242-8. Miller DT, Shen Y, Weiss LA, Korn J, Anselm I, Bridgemohan C, Cox GF, Dickinson H, Gentile J, Harris DJ, Hegde V, Hundley R, Khwaja O, Kothare S, Luedke C, Nasir R, Poduri A, Prasad K, Raffalli P, Reinhard A, Smith SE, Sobeih MM, Soul JS, Stoler J, Takeoka M, Tan WH, Thakuria J, Wolff R, Yusupov R, Gusella JF, Daly MJ, Wu BL. PMID: 18805830; PMCID: PMC4090085.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansCells
    51. Association Between Microdeletion and Microduplication at 16p11.2 and Autism. Obstetrical & Gynecological Survey. 2008 Jun 1; 63(6):361-363. Weiss WL, Shen SY, Korn KJ, Arking AD, Miller MD, Fossdal FR, Saemundsen SE, Stefansson SH, Ferreira FM, Green GT, Platt PO, Ruderfer RD, Walsh WC, Altshuler AD, Chakravarti CA, Tanzi TR, Stefansson SK, Santangelo SS, Gusella GJ, Sklar SP, Wu WB, Daly DM. .
      View in: Publisher Site   Mentions:
    52. Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med. 2008 Feb 14; 358(7):667-75. Weiss LA, Shen Y, Korn JM, Arking DE, Miller DT, Fossdal R, Saemundsen E, Stefansson H, Ferreira MA, Green T, Platt OS, Ruderfer DM, Walsh CA, Altshuler D, Chakravarti A, Tanzi RE, Stefansson K, Santangelo SL, Gusella JF, Sklar P, Wu BL, Daly MJ, Autism Consortium. PMID: 18184952.
      View in: PubMed   Mentions: 774     Fields:    Translation:HumansCells
    53. Disruption of neurexin 1 associated with autism spectrum disorder. Am J Hum Genet. 2008 Jan; 82(1):199-207. Kim HG, Kishikawa S, Higgins AW, Seong IS, Donovan DJ, Shen Y, Lally E, Weiss LA, Najm J, Kutsche K, Descartes M, Holt L, Braddock S, Troxell R, Kaplan L, Volkmar F, Klin A, Tsatsanis K, Harris DJ, Noens I, Pauls DL, Daly MJ, MacDonald ME, Morton CC, Quade BJ, Gusella JF. PMID: 18179900; PMCID: PMC2253961.
      View in: PubMed   Mentions: 282     Fields:    Translation:HumansCells
    54. Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life. J Allergy Clin Immunol. 2007 Jun; 119(6):1423-9. Thompson EE, Pan L, Ostrovnaya I, Weiss LA, Gern JE, Lemanske RF, Nicolae DL, Ober C. PMID: 17556058.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    55. Molecular genetics of the platelet serotonin system in first-degree relatives of patients with autism. Neuropsychopharmacology. 2008 Jan; 33(2):353-60. Cross S, Kim SJ, Weiss LA, Delahanty RJ, Sutcliffe JS, Leventhal BL, Cook EH, Veenstra-Vanderweele J. PMID: 17406648; PMCID: PMC2739682.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    56. Identification of EFHC2 as a quantitative trait locus for fear recognition in Turner syndrome. Hum Mol Genet. 2007 Jan 01; 16(1):107-13. Weiss LA, Purcell S, Waggoner S, Lawrence K, Spektor D, Daly MJ, Sklar P, Skuse D. PMID: 17164267.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    57. ITGB3 shows genetic and expression interaction with SLC6A4. Hum Genet. 2006 Aug; 120(1):93-100. Weiss LA, Ober C, Cook EH. PMID: 16721604.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    58. Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility. Eur J Hum Genet. 2006 Aug; 14(8):923-31. Weiss LA, Kosova G, Delahanty RJ, Jiang L, Cook EH, Ober C, Sutcliffe JS. PMID: 16724005.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    59. The sex-specific genetic architecture of quantitative traits in humans. Nat Genet. 2006 Feb; 38(2):218-22. Weiss LA, Pan L, Abney M, Ober C. PMID: 16429159.
      View in: PubMed   Mentions: 169     Fields:    Translation:Humans
    60. 431: Genome-Wide Screen Identifies Two Novel Loci Associated with Morning Serum Cortisol Levels in Women. American Journal of Epidemiology. 2005 Jun 27; 161(Supplement_1):s108-s108. Kurina KL, Weiss WL, Graves GS, Parry PR, Williams WG, Abney AM, Ober OC. .
      View in: Publisher Site   Mentions:
    61. Sex differences in the genetic basis of morning serum cortisol levels: genome-wide screen identifies two novel loci specific to women. J Clin Endocrinol Metab. 2005 Aug; 90(8):4747-52. Kurina LM, Weiss LA, Graves SW, Parry R, Williams GH, Abney M, Ober C. PMID: 15941864.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    62. Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample. Hum Genet. 2005 Jun; 117(1):81-7. Weiss LA, Abney M, Parry R, Scanu AM, Cook EH, Ober C. PMID: 15834589.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    63. Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations. Am J Respir Crit Care Med. 2005 Jul 01; 172(1):67-73. Weiss LA, Lester LA, Gern JE, Wolf RL, Parry R, Lemanske RF, Solway J, Ober C. PMID: 15817799; PMCID: PMC2718448.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    64. Sex-specific genetic architecture of whole blood serotonin levels. Am J Hum Genet. 2005 Jan; 76(1):33-41. Weiss LA, Abney M, Cook EH, Ober C. PMID: 15526234; PMCID: PMC1196431.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    65. Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin. Eur J Hum Genet. 2004 Nov; 12(11):949-54. Weiss LA, Veenstra-Vanderweele J, Newman DL, Kim SJ, Dytch H, McPeek MS, Cheng S, Ober C, Cook EH, Abney M. PMID: 15292919.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    66. Sodium channels SCN1A, SCN2A and SCN3A in familial autism. Mol Psychiatry. 2003 Feb; 8(2):186-94. Weiss LA, Escayg A, Kearney JA, Trudeau M, MacDonald BT, Mori M, Reichert J, Buxbaum JD, Meisler MH. PMID: 12610651.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansCells
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