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Katherine Possin, PhD

TitleAssociate Professor
InstitutionUniversity of California San Francisco
DepartmentNeurology
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-476-1889
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Research 
    Collapse Research Activities and Funding
    The Care Ecosystem: Navigating patients and caregivers through stages of dementia care
    NIH/NIA R01AG056715Sep 30, 2017 - May 31, 2022
    Role: Principal Investigator
    The UCSF Brain Health Assessment for the Detection of Cognitive Impairment Among Diverse Populations in Primary Care
    NIH/NINDS UG3NS105557Sep 25, 2017 - Aug 31, 2022
    Role: Principal Investigator
    Mechanisms of Spatial Cognitive Impairment in Neurodegenerative Disease
    NIH/NIA K23AG037566Jul 1, 2011 - Jun 30, 2016
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites
    Collapse In The News
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Possin K, Moskowitz T, Erlhoff SJ, Rogers KM, Johnson ET, Steele NZR, Higgins JJ, Stiver J, Alioto AG, Farias ST, Miller BL, Rankin KP. The Brain Health Assessment for Detecting and Diagnosing Neurocognitive Disorders. J Am Geriatr Soc. 2018 Jan; 66(1):150-156. PMID: 29355911.
      View in: PubMed
    2. Perry DC, Brown JA, Possin K, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, Lee SE, Matthews BR, Kao AW, Vossel KA, Tartaglia MC, Miller ZA, Seo SW, Sidhu M, Gaus SE, Nana AL, Vargas JNS, Hwang JL, Ossenkoppele R, Brown AB, Huang EJ, Coppola G, Rosen HJ, Geschwind D, Trojanowski JQ, Grinberg LT, Kramer JH, Miller BL, Seeley WW. Clinicopathological correlations in behavioural variant frontotemporal dementia. Brain. 2017 Dec 01; 140(12):3329-3345. PMID: 29053860.
      View in: PubMed
    3. Watson CL, Possin K, Allen IE, Hubbard HI, Meyer M, Welch AE, Rabinovici GD, Rosen H, Rankin KP, Miller Z, Santos-Santos MA, Kramer JH, Miller BL, Gorno-Tempini ML. Visuospatial Functioning in the Primary Progressive Aphasias. J Int Neuropsychol Soc. 2018 Mar; 24(3):259-268. PMID: 29039275.
      View in: PubMed
    4. Kim H, Kim JH, Possin K, Winer J, Geschwind MD, Xu D, Hess CP. Surface-based morphometry reveals caudate subnuclear structural damage in patients with premotor Huntington disease. Brain Imaging Behav. 2017 Oct; 11(5):1365-1372. PMID: 27730480.
      View in: PubMed
    5. Zylstra B, Netscher G, Jacquemot J, Schaffer M, Shen G, Bowhay AD, Braley TL, Possin K, Miller BL, Bayen AM, Bonasera SJ, Schenk AK. Extended, continuous measures of functional status in community dwelling persons with Alzheimer's and related dementia: Infrastructure, performance, tradeoffs, preliminary data, and promise. J Neurosci Methods. 2018 Apr 15; 300:59-67. PMID: 28865985.
      View in: PubMed
    6. Miaskowski C, Wong ML, Cooper BA, Mastick J, Paul SM, Possin K, Steinman M, Cataldo J, Dunn LB, Ritchie C. Distinct Physical Function Profiles in Older Adults Receiving Cancer Chemotherapy. J Pain Symptom Manage. 2017 Sep; 54(3):263-272. PMID: 28716620.
      View in: PubMed
    7. Possin K, Kim H, Geschwind MD, Moskowitz T, Johnson ET, Sha SJ, Apple A, Xu D, Miller BL, Finkbeiner S, Hess CP, Kramer JH. Egocentric and allocentric visuospatial working memory in premotor Huntington's disease: A double dissociation with caudate and hippocampal volumes. Neuropsychologia. 2017 Jul 01; 101:57-64. PMID: 28427989.
      View in: PubMed
    8. Possin K, Merrilees J, Bonasera SJ, Bernstein A, Chiong W, Lee K, Wilson L, Hooper SM, Dulaney S, Braley T, Laohavanich S, Feuer JE, Clark AM, Schaffer MW, Schenk AK, Heunis J, Ong P, Cook KM, Bowhay AD, Gearhart R, Chodos A, Naasan G, Bindman AB, Dohan D, Ritchie C, Miller BL. Development of an adaptive, personalized, and scalable dementia care program: Early findings from the Care Ecosystem. PLoS Med. 2017 Mar; 14(3):e1002260. PMID: 28323819.
      View in: PubMed
    9. Bertoux M, Sarazin M, Pasquier F, Bottlaender M, de Souza LC, Mioshi E, Hornberger M, Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, You SC, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL. Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 10 04; 87(14):1523. PMID: 27698154.
      View in: PubMed
    10. Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin K, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL. Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurol. 2016 Sep 01; 73(9):1078-88. PMID: 27429218.
      View in: PubMed
    11. Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, Christine You S, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL. Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 Feb 16; 86(7):600-10. PMID: 26802093.
      View in: PubMed
    12. Possin K, Sanchez PE, Anderson-Bergman C, Fernandez R, Kerchner GA, Johnson ET, Davis A, Lo I, Bott NT, Kiely T, Fenesy MC, Miller BL, Kramer JH, Finkbeiner S. Cross-species translation of the Morris maze for Alzheimer's disease. J Clin Invest. 2016 Feb; 126(2):779-83. PMID: 26784542; PMCID: PMC4731157.
      View in: PubMed, PubMed Central
    13. Walker Z, Possin K, Boeve BF, Aarsland D. Lewy body dementias. Lancet. 2015 Oct 24; 386(10004):1683-97. PMID: 26595642.
      View in: PubMed
    14. Alty JE, Cosgrove J, Jamieson S, Smith SL, Possin K. Which figure copy test is more sensitive for cognitive impairment in Parkinson's disease: Wire cube or interlocking pentagons? Clin Neurol Neurosurg. 2015 Dec; 139:244-6. PMID: 26519897.
      View in: PubMed
    15. Gardner RC, Possin K, Hess CP, Huang EJ, Grinberg LT, Nolan AL, Cohn-Sheehy BI, Ghosh PM, Lanata S, Merrilees J, Kramer JH, Berger MS, Miller BL, Yaffe K, Rabinovici GD. Evaluating and treating neurobehavioral symptoms in professional American football players: Lessons from a case series. Neurol Clin Pract. 2015 Aug; 5(4):285-295. PMID: 26336629.
      View in: PubMed
    16. Gardner RC, Hess CP, Brus-Ramer M, Possin K, Cohn-Sheehy BI, Kramer JH, Berger MS, Yaffe K, Miller B, Rabinovici GD. Cavum Septum Pellucidum in Retired American Pro-Football Players. J Neurotrauma. 2016 Jan 01; 33(1):157-61. PMID: 25970145; PMCID: PMC4696427 [Available on 01/01/17].
      View in: PubMed, PubMed Central
    17. Rabinovici GD, Stephens ML, Possin K. Executive dysfunction. Continuum (Minneap Minn). 2015 Jun; 21(3 Behavioral Neurology and Neuropsychiatry):646-59. PMID: 26039846.
      View in: PubMed
    18. Migliaccio R, Agosta F, Possin K, Canu E, Filippi M, Rabinovici GD, Rosen HJ, Miller BL, Gorno-Tempini ML. Mapping the Progression of Atrophy in Early- and Late-Onset Alzheimer's Disease. J Alzheimers Dis. 2015; 46(2):351-64. PMID: 25737041; PMCID: PMC4559486.
      View in: PubMed, PubMed Central
    19. Bott NT, Johnson ET, Schuff N, Galifianakis N, Subas T, Pollock J, Pressman P, Kramer JH, Possin K. Sensitive measures of executive dysfunction in non-demented Parkinson's disease. Parkinsonism Relat Disord. 2014 Dec; 20(12):1430-3. PMID: 25454318; PMCID: PMC4314390.
      View in: PubMed, PubMed Central
    20. You SC, Geschwind MD, Sha SJ, Apple A, Satris G, Wood KA, Johnson ET, Gooblar J, Feuerstein JS, Finkbeiner S, Kang GA, Miller BL, Hess CP, Kramer JH, Possin K. Executive functions in premanifest Huntington's disease. Mov Disord. 2014 Mar; 29(3):405-9. PMID: 24375511; PMCID: PMC4029327.
      View in: PubMed, PubMed Central
    21. Geschwind MD, Kuo AL, Wong KS, Haman A, Devereux G, Raudabaugh BJ, Johnson DY, Torres-Chae CC, Finley R, Garcia P, Thai JN, Cheng HQ, Neuhaus JM, Forner SA, Duncan JL, Possin K, Dearmond SJ, Prusiner SB, Miller BL. Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease. Neurology. 2013 Dec 03; 81(23):2015-23. PMID: 24122181; PMCID: PMC4211922.
      View in: PubMed, PubMed Central
    22. Kramer JH, Mungas D, Possin K, Rankin KP, Boxer AL, Rosen HJ, Bostrom A, Sinha L, Berhel A, Widmeyer M. NIH EXAMINER: conceptualization and development of an executive function battery. J Int Neuropsychol Soc. 2014 Jan; 20(1):11-9. PMID: 24103232; PMCID: PMC4474183.
      View in: PubMed, PubMed Central
    23. Schreiber JE, Possin K, Girard JM, Rey-Casserly C. Executive function in children with attention deficit/hyperactivity disorder: the NIH EXAMINER battery. J Int Neuropsychol Soc. 2014 Jan; 20(1):41-51. PMID: 24103310; PMCID: PMC4425416.
      View in: PubMed, PubMed Central
    24. Possin K, Kang GA, Guo C, Fine EM, Trujillo AJ, Racine CA, Wilheim R, Johnson ET, Witt JL, Seeley WW, Miller BL, Kramer JH. Rivastigmine is associated with restoration of left frontal brain activity in Parkinson's disease. Mov Disord. 2013 Sep; 28(10):1384-90. PMID: 23847120; PMCID: PMC4001926.
      View in: PubMed, PubMed Central
    25. Possin K, LaMarre AK, Wood KA, Mungas DM, Kramer JH. Ecological validity and neuroanatomical correlates of the NIH EXAMINER executive composite score. J Int Neuropsychol Soc. 2014 Jan; 20(1):20-8. PMID: 23764015; PMCID: PMC4059410.
      View in: PubMed, PubMed Central
    26. Possin K, Feigenbaum D, Rankin KP, Smith GE, Boxer AL, Wood K, Hanna SM, Miller BL, Kramer JH. Dissociable executive functions in behavioral variant frontotemporal and Alzheimer dementias. Neurology. 2013 Jun 11; 80(24):2180-5. PMID: 23658382; PMCID: PMC3721104.
      View in: PubMed, PubMed Central
    27. Migliaccio R, Agosta F, Possin K, Rabinovici GD, Miller BL, Gorno-Tempini ML. White matter atrophy in Alzheimer's disease variants. Alzheimers Dement. 2012 Oct; 8(5 Suppl):S78-87.e1-2. PMID: 23021625; PMCID: PMC3717610.
      View in: PubMed, PubMed Central
    28. Possin K, Chester SK, Laluz V, Bostrom A, Rosen HJ, Miller BL, Kramer JH. The frontal-anatomic specificity of design fluency repetitions and their diagnostic relevance for behavioral variant frontotemporal dementia. J Int Neuropsychol Soc. 2012 Sep; 18(5):834-44. PMID: 22835330; PMCID: PMC3620020.
      View in: PubMed, PubMed Central
    29. Zhan W, Kang GA, Glass GA, Zhang Y, Shirley C, Millin R, Possin K, Nezamzadeh M, Weiner MW, Marks WJ, Schuff N. Regional alterations of brain microstructure in Parkinson's disease using diffusion tensor imaging. Mov Disord. 2012 Jan; 27(1):90-7. PMID: 21850668; PMCID: PMC4472452.
      View in: PubMed, PubMed Central
    30. Silverberg NB, Ryan LM, Carrillo MC, Sperling R, Petersen RC, Posner HB, Snyder PJ, Hilsabeck R, Gallagher M, Raber J, Rizzo A, Possin K, King J, Kaye J, Ott BR, Albert MS, Wagster MV, Schinka JA, Cullum CM, Farias ST, Balota D, Rao S, Loewenstein D, Budson AE, Brandt J, Manly JJ, Barnes L, Strutt A, Gollan TH, Ganguli M, Babcock D, Litvan I, Kramer JH, Ferman TJ. Assessment of cognition in early dementia. Alzheimers Dement. 2011 May 01; 7(3):e60-e76. PMID: 23559893.
      View in: PubMed
    31. Possin K, Laluz VR, Alcantar OZ, Miller BL, Kramer JH. Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementia. Neuropsychologia. 2011 Jan; 49(1):43-8. PMID: 21029744; PMCID: PMC3005024.
      View in: PubMed, PubMed Central
    32. Possin K. Visual spatial cognition in neurodegenerative disease. Neurocase. 2010 Dec; 16(6):466-87. PMID: 20526954; PMCID: PMC3028935.
      View in: PubMed, PubMed Central
    33. Pa J, Possin K, Wilson SM, Quitania LC, Kramer JH, Boxer AL, Weiner MW, Johnson JK. Gray matter correlates of set-shifting among neurodegenerative disease, mild cognitive impairment, and healthy older adults. J Int Neuropsychol Soc. 2010 Jul; 16(4):640-50. PMID: 20374676; PMCID: PMC2891121.
      View in: PubMed, PubMed Central
    34. Possin K, Kaufer DI. Parkinsonian dementias. Continuum (Minneap Minn). 2010 Apr; 16(2 Dementia):57-79. PMID: 22810281.
      View in: PubMed
    35. Luks TL, Oliveira M, Possin K, Bird A, Miller BL, Weiner MW, Kramer JH. Atrophy in two attention networks is associated with performance on a Flanker task in neurodegenerative disease. Neuropsychologia. 2010 Jan; 48(1):165-70. PMID: 19747928; PMCID: PMC3018338.
      View in: PubMed, PubMed Central
    36. Possin K, Brambati SM, Rosen HJ, Johnson JK, Pa J, Weiner MW, Miller BL, Kramer JH. Rule violation errors are associated with right lateral prefrontal cortex atrophy in neurodegenerative disease. J Int Neuropsychol Soc. 2009 May; 15(3):354-64. PMID: 19402921; PMCID: PMC2748220.
      View in: PubMed, PubMed Central
    37. Possin K, Filoteo JV, Song DD, Salmon DP. Space-based but not object-based inhibition of return is impaired in Parkinson's disease. Neuropsychologia. 2009 Jun; 47(7):1694-700. PMID: 19397864; PMCID: PMC2696984.
      View in: PubMed, PubMed Central
    38. Agosta F, Vossel KA, Miller BL, Migliaccio R, Bonasera SJ, Filippi M, Boxer AL, Karydas A, Possin K, Gorno-Tempini ML. Apolipoprotein E epsilon4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia. Proc Natl Acad Sci U S A. 2009 Feb 10; 106(6):2018-22. PMID: 19164761; PMCID: PMC2644156.
      View in: PubMed, PubMed Central
    39. Possin K, Filoteo JV, Song DD, Salmon DP. Spatial and object working memory deficits in Parkinson's disease are due to impairment in different underlying processes. Neuropsychology. 2008 Sep; 22(5):585-95. PMID: 18763878; PMCID: PMC2862562.
      View in: PubMed, PubMed Central
    40. Wittenberg D, Possin K, Rascovsky K, Rankin KP, Miller BL, Kramer JH. The early neuropsychological and behavioral characteristics of frontotemporal dementia. Neuropsychol Rev. 2008 Mar; 18(1):91-102. PMID: 18311522; PMCID: PMC3000668.
      View in: PubMed, PubMed Central
    41. Viskontas IV, Possin K, Miller BL. Symptoms of frontotemporal dementia provide insights into orbitofrontal cortex function and social behavior. Ann N Y Acad Sci. 2007 Dec; 1121:528-45. PMID: 17846163.
      View in: PubMed
    42. Possin K, Cagigas XE, Strayer DL, Filoteo JV. Lack of impairment in patients with Parkinson's disease on an object-based negative priming task. Percept Mot Skills. 2006 Feb; 102(1):219-30. PMID: 16671622.
      View in: PubMed
    43. Zizak VS, Filoteo JV, Possin K, Lucas JA, Rilling LM, Davis JD, Peavy G, Wong A, Salmon DP. The ubiquity of memory retrieval deficits in patients with frontal-striatal dysfunction. Cogn Behav Neurol. 2005 Dec; 18(4):198-205. PMID: 16340392.
      View in: PubMed
    44. Possin K, Filoteo JV, Roesch SC, Zizak V, Rilling LM, Davis JD. Is a perseveration a perseveration? An evaluation of cognitive error types in patients with subcortical pathology. J Clin Exp Neuropsychol. 2005 Nov; 27(8):953-66. PMID: 16207620.
      View in: PubMed
    45. Nordahl TE, Salo R, Possin K, Gibson DR, Flynn N, Leamon M, Galloway GP, Pfefferbaum A, Spielman DM, Adalsteinsson E, Sullivan EV. Low N-acetyl-aspartate and high choline in the anterior cingulum of recently abstinent methamphetamine-dependent subjects: a preliminary proton MRS study. Magnetic resonance spectroscopy. Psychiatry Res. 2002 Nov 30; 116(1-2):43-52. PMID: 12426033.
      View in: PubMed
    46. Salo R, Nordahl TE, Possin K, Leamon M, Gibson DR, Galloway GP, Flynn NM, Henik A, Pfefferbaum A, Sullivan EV. Preliminary evidence of reduced cognitive inhibition in methamphetamine-dependent individuals. Psychiatry Res. 2002 Aug 05; 111(1):65-74. PMID: 12140121.
      View in: PubMed
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