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Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight. Diabetes. 2016 09; 65(9):2732-41.
Sisley SR, Arble DM, Chambers AP, Gutierrez-Aguilar R, He Y, Xu Y, Gardner D, Moore DD, Seeley RJ, Sandoval DA. PMID: 27217488; PMCID: PMC5001188.
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22 Fields:
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Amplification of lipotoxic cardiomyopathy in the VDR gene knockout mouse. J Steroid Biochem Mol Biol. 2016 11; 164:292-298.
Glenn DJ, Cardema MC, Gardner DG. PMID: 26429397.
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9 Fields:
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Tie-2Cre mediated deletion of the vitamin D receptor gene leads to improved skeletal muscle insulin sensitivity and glucose tolerance. J Steroid Biochem Mol Biol. 2016 11; 164:281-286.
Ni W, Glenn DJ, Gardner DG. PMID: 26369613; PMCID: PMC4788578.
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6 Fields:
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Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function. PLoS One. 2015; 10(7):e0131539.
Jeffery LE, Qureshi OS, Gardner D, Hou TZ, Briggs Z, Soskic B, Baker J, Raza K, Sansom DM. PMID: 26134669; PMCID: PMC4489761.
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29 Fields:
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HumansAnimalsCells
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Cardiac steatosis potentiates angiotensin II effects in the heart. Am J Physiol Heart Circ Physiol. 2015 Feb 15; 308(4):H339-50.
Glenn DJ, Cardema MC, Ni W, Zhang Y, Yeghiazarians Y, Grapov D, Fiehn O, Gardner DG. PMID: 25485904; PMCID: PMC4329483.
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17 Fields:
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Elimination of vitamin D receptor in vascular endothelial cells alters vascular function. Hypertension. 2014 Dec; 64(6):1290-8.
Ni W, Watts SW, Ng M, Chen S, Glenn DJ, Gardner DG. PMID: 25201890; PMCID: PMC4430199.
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79 Fields:
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Vitamin D and the heart. Am J Physiol Regul Integr Comp Physiol. 2013 Nov 01; 305(9):R969-77.
Gardner DG, Chen S, Glenn DJ. PMID: 24026071; PMCID: PMC3840320.
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32 Fields:
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Vitamin D: beyond bone. Ann N Y Acad Sci. 2013 May; 1287:45-58.
Christakos S, Hewison M, Gardner DG, Wagner CL, Sergeev IN, Rutten E, Pittas AG, Boland R, Ferrucci L, Bikle DD. PMID: 23682710; PMCID: PMC3717170.
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109 Fields:
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Acute liver failure with thyrotoxicosis treated with liver transplantation. Endocr Pract. 2013 May-Jun; 19(3):e57-60.
Cascino MD, McNabb B, Gardner DG, Woeber KA, Fox AN, Wang B, Fix OK. PMID: 23337142.
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1 Fields:
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Humans
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Liganded vitamin D receptor displays anti-hypertrophic activity in the murine heart. J Steroid Biochem Mol Biol. 2013 Jul; 136:150-5.
Chen S, Gardner DG. PMID: 22989481.
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13 Fields:
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AnimalsCells
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Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a role for C-type natriuretic peptide. Endocr Relat Cancer. 2012 Aug; 19(4):497-508.
Thompson IR, Chand AN, King PJ, Ansorge O, Karavitaki N, Jones CA, Rahmutula D, Gardner DG, Zivkovic V, Wheeler-Jones CP, McGonnell IM, Korbonits M, Anderson RA, Wass JA, McNeilly AS, Fowkes RC. PMID: 22645228.
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10 Fields:
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HumansAnimalsCells
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Effect of combining an ACE inhibitor and a VDR activator on glomerulosclerosis, proteinuria, and renal oxidative stress in uremic rats. Am J Physiol Renal Physiol. 2012 Jan 01; 302(1):F141-9.
Finch JL, Suarez EB, Husain K, Ferder L, Cardema MC, Glenn DJ, Gardner DG, Liapis H, Slatopolsky E. PMID: 21957179.
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32 Fields:
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Animals
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Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy. Circulation. 2011 Oct 25; 124(17):1838-47.
Chen S, Law CS, Grigsby CL, Olsen K, Hong TT, Zhang Y, Yeghiazarians Y, Gardner DG. PMID: 21947295; PMCID: PMC4160312.
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156 Fields:
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A murine model of isolated cardiac steatosis leads to cardiomyopathy. Hypertension. 2011 Feb; 57(2):216-22.
Glenn DJ, Wang F, Nishimoto M, Cruz MC, Uchida Y, Holleran WM, Zhang Y, Yeghiazarians Y, Gardner DG. PMID: 21220706; PMCID: PMC3322545.
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40 Fields:
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Chapter 31 Vitamin D and the Cardiovascular System. Vitamin D. 2011 Jan 1; 541-563.
Gardner GD, Chen CS, Glenn GD, Ni NW. .
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A role for the cell cycle phosphatase Cdc25a in vitamin D-dependent inhibition of adult rat vascular smooth muscle cell proliferation. J Steroid Biochem Mol Biol. 2010 Nov; 122(5):326-32.
Chen S, Law CS, Grigsby CL, Olsen K, Gardner DG. PMID: 20813185; PMCID: PMC4143149.
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12 Fields:
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Vitamin D-dependent suppression of endothelin-induced vascular smooth muscle cell proliferation through inhibition of CDK2 activity. J Steroid Biochem Mol Biol. 2010 Feb 15; 118(3):135-41.
Chen S, Law CS, Gardner DG. PMID: 19961935; PMCID: PMC2830853.
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29 Fields:
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Atrial natriuretic peptide suppresses endothelin gene expression and proliferation in cardiac fibroblasts through a GATA4-dependent mechanism. Cardiovasc Res. 2009 Nov 01; 84(2):209-17.
Glenn DJ, Rahmutula D, Nishimoto M, Liang F, Gardner DG. PMID: 19546173; PMCID: PMC2761198.
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18 Fields:
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AnimalsCells
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Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents. J Clin Invest. 2009 Jun; 119(6):1647-58.
Chen S, Grigsby CL, Law CS, Ni X, Nekrep N, Olsen K, Humphreys MH, Gardner DG. PMID: 19436108; PMCID: PMC2689130.
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33 Fields:
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Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2. Hypertension. 2009 Mar; 53(3):549-55.
Glenn DJ, Wang F, Chen S, Nishimoto M, Gardner DG. PMID: 19139378; PMCID: PMC2710878.
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23 Fields:
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HumansAnimalsCells
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Expression of the vitamin d receptor is increased in the hypertrophic heart. Hypertension. 2008 Dec; 52(6):1106-12.
Chen S, Glenn DJ, Ni W, Grigsby CL, Olsen K, Nishimoto M, Law CS, Gardner DG. PMID: 18936343; PMCID: PMC2690395.
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70 Fields:
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Lipids and the heart: neither feast nor famine. Hypertension. 2007 Sep; 50(3):463-4.
Glenn DJ, Gardner DG. PMID: 17664386.
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1 Fields:
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HumansAnimals
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Molecular biology of the natriuretic peptide system: implications for physiology and hypertension. Hypertension. 2007 Mar; 49(3):419-26.
Gardner DG, Chen S, Glenn DJ, Grigsby CL. PMID: 17283251.
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45 Fields:
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Molecular aspects of the natriuretic peptide system. Molecular Mechanisms in Hypertension. 2006 Apr 19; 199-209.
Gardner GD, Chen CS, Rahmutula RD, Wang WF, Olsen OK. .
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Hypernatremia predicts adverse cardiovascular and neurological outcomes after SAH. Neurocrit Care. 2006; 5(3):180-5.
Fisher LA, Ko N, Miss J, Tung PP, Kopelnik A, Banki NM, Gardner D, Smith WS, Lawton MT, Zaroff JG. PMID: 17290085.
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22 Fields:
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Humans
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A role for p38 mitogen-activated protein kinase and c-myc in endothelin-dependent rat aortic smooth muscle cell proliferation. Hypertension. 2006 Feb; 47(2):252-8.
Chen S, Qiong Y, Gardner DG. PMID: 16365184.
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17 Fields:
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AnimalsCells
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C-type natriuretic Peptide down-regulates expression of its cognate receptor in rat aortic smooth muscle cells. Endocrinology. 2005 Nov; 146(11):4968-74.
Rahmutula D, Gardner DG. PMID: 16109786.
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6 Fields:
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AnimalsCells
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1,25-dihydroxyvitamin D inhibits human ANP gene promoter activity. Regul Pept. 2005 Jun 30; 128(3):197-202.
Chen S, Nakamura K, Gardner DG. PMID: 15837528.
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3 Fields:
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HumansAnimalsCells
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1,25 dihydroxyvitamin d amplifies type a natriuretic peptide receptor expression and activity in target cells. J Am Soc Nephrol. 2005 Feb; 16(2):329-39.
Chen S, Ni XP, Humphreys MH, Gardner DG. PMID: 15590756.
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7 Fields:
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Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E125-32.
Xiang W, Kong J, Chen S, Cao LP, Qiao G, Zheng W, Liu W, Li X, Gardner DG, Li YC. PMID: 15367398.
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199 Fields:
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Transcriptional regulation of type B human natriuretic Peptide receptor gene promoter: dependence on Sp1. Hypertension. 2004 Sep; 44(3):283-8.
Rahmutula D, Cui J, Chen S, Gardner DG. PMID: 15262909.
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3 Fields:
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Sgk1 mediates osmotic induction of NPR-A gene in rat inner medullary collecting duct cells. Hypertension. 2004 Apr; 43(4):866-71.
Chen S, McCormick JA, Prabaker K, Wang J, Pearce D, Gardner DG. PMID: 15007040.
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8 Fields:
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Suppression of WEE1 and stimulation of CDC25A correlates with endothelin-dependent proliferation of rat aortic smooth muscle cells. J Biol Chem. 2004 Apr 02; 279(14):13755-63.
Chen S, Gardner DG. PMID: 14742443.
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8 Fields:
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Role of the epidermal growth factor receptor in signaling strain-dependent activation of the brain natriuretic peptide gene. J Biol Chem. 2004 Mar 05; 279(10):9287-97.
Anderson HD, Wang F, Gardner DG. PMID: 14645255.
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11 Fields:
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Natriuretic peptides: markers or modulators of cardiac hypertrophy? Trends Endocrinol Metab. 2003 Nov; 14(9):411-6.
Gardner DG. PMID: 14580760.
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47 Fields:
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Humans
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Tumor necrosis factor-alpha inhibits endothelial nitric-oxide synthase gene promoter activity in bovine aortic endothelial cells. J Biol Chem. 2004 Jan 09; 279(2):963-9.
Anderson HD, Rahmutula D, Gardner DG. PMID: 14581470.
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61 Fields:
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Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes. Endocrinology. 2003 Sep; 144(9):4187-94.
Liang F, Wang F, Zhang S, Gardner DG. PMID: 12933694.
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24 Fields:
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Brain natriuretic peptide: a marker for subclinical cardiovascular disease? Am J Med. 2003 Mar; 114(4):329-30.
Gardner DG. PMID: 12681464.
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Focal adhesion kinase is required for blood vessel morphogenesis. Circ Res. 2003 Feb 21; 92(3):300-7.
Ilic D, Kovacic B, McDonagh S, Jin F, Baumbusch C, Gardner DG, Damsky CH. PMID: 12595342.
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47 Fields:
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Triiodothyronine increases brain natriuretic peptide (BNP) gene transcription and amplifies endothelin-dependent BNP gene transcription and hypertrophy in neonatal rat ventricular myocytes. J Biol Chem. 2003 Apr 25; 278(17):15073-83.
Liang F, Webb P, Marimuthu A, Zhang S, Gardner DG. PMID: 12562779.
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22 Fields:
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Endothelin inhibits NPR-A and stimulates eNOS gene expression in rat IMCD cells. Hypertension. 2003 Mar; 41(3 Pt 2):675-81.
Ye Q, Chen S, Gardner DG. PMID: 12623978.
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12 Fields:
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AnimalsCells
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Osmoregulation of endothelial nitric-oxide synthase gene expression in inner medullary collecting duct cells. Role in activation of the type A natriuretic peptide receptor. J Biol Chem. 2002 Sep 06; 277(36):32498-504.
Chen S, Cao L, Intengan HD, Humphreys M, Gardner DG. PMID: 12082097.
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6 Fields:
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Manipulating the renin-angiotensin system: more than we bargained for? Am J Med. 2002 Feb 01; 112(2):152-3.
Gardner DG. PMID: 11835956.
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Thyroid Hormone Export Varies among Primary Cells and Appears to Differ from Hormone Uptake. Endocrinology. 2002 Feb 1; 143(2):476-483.
Neves NF, Cavalieri CR, Simeoni SL, Gardner GD, Baxter BJ, Scharschmidt SB, Lomri LN, Ribeiro RR. .
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Thyroid hormone export varies among primary cells and appears to differ from hormone uptake. Endocrinology. 2002 Feb; 143(2):476-83.
Neves FA, Cavalieri RR, Simeoni LA, Gardner DG, Baxter JD, Scharschmidt BF, Lomri N, Ribeiro RC. PMID: 11796501.
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3 Fields:
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Requirements for the localization of p130 Cas to Z-lines in cardiac myocytes. Cell Mol Biol Lett. 2002; 7(2):323-9.
Kovacic-Milivojevic B, Damsky CC, Gardner DG, Ilic D. PMID: 12097978.
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5 Fields:
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Osmoregulation of natriuretic peptide receptor signaling in inner medullary collecting duct. A requirement for p38 MAPK. J Biol Chem. 2002 Feb 22; 277(8):6037-43.
Chen S, Gardner DG. PMID: 11744737.
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8 Fields:
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Sp1 Dependence of Natriuretic Peptide Receptor A Gene Transcription in Rat Aortic Smooth Muscle Cells
1. Endocrinology. 1999 Apr 1; 140(4):1695-1701.
Liang LF, Schaufele SF, Gardner GD. .
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Sp1 Dependence of Natriuretic Peptide Receptor A Gene Transcription in Rat Aortic Smooth Muscle Cells*. Endocrinology. 1999 Apr 1; 140(4):1695-1701.
Liang LF, Schaufele SF, Gardner GD. .
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Natriuretic Peptides and the Heart. Hormones and the Heart in Health and Disease. 1999 Jan 1; 1-20.
Gardner GD, Kovacic-Milivojevic KB, Liang LF, Chen CS. .
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Cellular and Molecular Aspects of the A-Type Natriuretic Peptide. Natriuretic Peptides in Health and Disease. 1997 Jan 1; 71-94.
Gardner GD, Wu WJ, Kovacic-Milivojevic KB. .
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Divergent regulation of the human atrial natriuretic peptide gene by c-jun and c-fos. Molecular and Cellular Biology. 1992 Jan 1; 12(1):292-301.
Kovacic-Milivojevic KB, Gardner GD. .
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Divergent Regulation of the Human Atrial Natriuretic Peptide Gene by c-jun and c-fos. Molecular and Cellular Biology. 1992 Jan 1; 12(1):292-301.
Kovacic-Milivojevic KB, Gardner GD. .
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42 Extravascular shift of fluid and albumin induced by endothelin in binephrectomized rats. Journal of Hypertension. 1991 Sep 1; 9(9):885.
Valentin VJ, Gardner GD, Ribstein RJ, Mimran MA, Humphreys HM. .
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Atrial Natriuretic Peptide. Nature Biotechnology. 1988 May 1; 6(5):529-546.
Baxter BJ, Lewicki LJ, Gardner GD. .
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THE GROWTH HORMONE GENE FAMILY: STRUCTURE, EVOLUTION, EXPRESSION, AND REGULATION11This work was supported by NIH Grants AM19997 and AM18878 and NSF Grant 8004735. Gene Regulation. 1982 Jan 1; 235-251.
Eberhardt EN, Selby SM, Cathala CG, Karin KM, Gutierrez-Hartmann GA, Mellon MS, Lan LN, Gardner GD, Baxter BJ. .
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