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Wade Smith, MD, PhD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentNeurology
Address505 Parnassus Avenue
San Francisco CA 94117
Phone415-353-1489
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    NorCal - Coordinating Stroke Center
    NIH/NINDS U10NS086494Sep 30, 2013 - Jul 31, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Clinical Trials
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Caganap SD, Smith W. Endovascular Stroke Therapy. Semin Thromb Hemost. 2017 Jul 27. PMID: 28750424.
      View in: PubMed
    2. Lima FO, Silva GS, Furie KL, Frankel MR, Lev MH, Camargo ÉC, Haussen DC, Singhal AB, Koroshetz WJ, Smith W, Nogueira RG. Field Assessment Stroke Triage for Emergency Destination: A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes. Stroke. 2016 Aug; 47(8):1997-2002. PMID: 27364531; PMCID: PMC4961538 [Available on 08/01/17].
    3. Chapman Smith SN, Govindarajan P, Padrick MM, Lippman JM, McMurry TL, Resler BL, Keenan K, Gunnell BS, Mehndiratta P, Chee CY, Cahill EA, Dietiker C, Cattell-Gordon DC, Smith W, Perina DG, Solenski NJ, Worrall BB, Southerland AM. A low-cost, tablet-based option for prehospital neurologic assessment: The iTREAT Study. Neurology. 2016 Jul 05; 87(1):19-26. PMID: 27281534; PMCID: PMC4932237 [Available on 07/05/17].
    4. Miller CM, Pineda J, Corry M, Brophy G, Smith W. Emergency Neurologic Life Support (ENLS): Evolution of Management in the First Hour of a Neurological Emergency. Neurocrit Care. 2015 Dec; 23 Suppl 2:S1-4. PMID: 26438452.
      View in: PubMed
    5. Smith W, Browne JL, Ko NU. Cranial Accelerometry Can Detect Cerebral Vasospasm Caused by Subarachnoid Hemorrhage. Neurocrit Care. 2015 Dec; 23(3):364-9. PMID: 25761424.
      View in: PubMed
    6. Smith W, Furlan AJ. Brief History of Endovascular Acute Ischemic Stroke Treatment. Stroke. 2016 Feb; 47(2):e23-6. PMID: 26429995.
      View in: PubMed
    7. Smith W, Yan B. REVASCAT Trial: Further Advancement in Endovascular Stroke Therapy. Stroke. 2015 Oct; 46(10):3012-3. PMID: 26337972.
      View in: PubMed
    8. Flint AC, Rao VA, Chan SL, Cullen SP, Faigeles BS, Smith W, Bath PM, Wahlgren N, Ahmed N, Donnan GA, Johnston SC. Improved ischemic stroke outcome prediction using model estimation of outcome probability: the THRIVE-c calculation. Int J Stroke. 2015 Aug; 10(6):815-21. PMID: 26045081.
      View in: PubMed
    9. Auerbach PS, Baine JG, Schott ML, Greenhaw A, Acharya MG, Smith W. Detection of concussion using cranial accelerometry. Clin J Sport Med. 2015 Mar; 25(2):126-32. PMID: 25010149.
      View in: PubMed
    10. Zaidat OO, Fitzsimmons BF, Woodward BK, Wang Z, Killer-Oberpfalzer M, Wakhloo A, Gupta R, Kirshner H, Megerian JT, Lesko J, Pitzer P, Ramos J, Castonguay AC, Barnwell S, Smith W, Gress DR. Effect of a balloon-expandable intracranial stent vs medical therapy on risk of stroke in patients with symptomatic intracranial stenosis: the VISSIT randomized clinical trial. JAMA. 2015 Mar 24-31; 313(12):1240-8. PMID: 25803346.
      View in: PubMed
    11. Chan S, Josephson SA, Rosow L, Smith W. A quality assurance initiative targeting radiation exposure to neuroscience patients in the intensive care unit. Neurohospitalist. 2015 Jan; 5(1):9-14. PMID: 25553223; PMCID: PMC4272353.
    12. Guterman EL, Kamel H, Azran C, Shah MP, Claude Hemphill J, Smith W, Navi BB. Time from onset of SIRS to antibiotic administration and outcomes after subarachnoid hemorrhage. Neurocrit Care. 2014 Aug; 21(1):85-90. PMID: 23839708.
      View in: PubMed
    13. Flint AC, Gupta R, Smith W, Kamel H, Faigeles BS, Cullen SP, Rao VA, Bath PM, Wahlgren N, Ahmed N, Donnan GA. The THRIVE score predicts symptomatic intracerebral hemorrhage after intravenous tPA administration in SITS-MOST. Int J Stroke. 2014 Aug; 9(6):705-10. PMID: 25042855.
      View in: PubMed
    14. Shi ZS, Liebeskind DS, Xiang B, Ge SG, Feng L, Albers GW, Budzik R, Devlin T, Gupta R, Jansen O, Jovin TG, Killer-Oberpfalzer M, Lutsep HL, Macho J, Nogueira RG, Rymer M, Smith W, Wahlgren N, Duckwiler GR. Predictors of functional dependence despite successful revascularization in large-vessel occlusion strokes. Stroke. 2014 Jul; 45(7):1977-84. PMID: 24876082; PMCID: PMC4160889.
    15. Liebeskind DS, Flint AC, Budzik RF, Xiang B, Smith W, Duckwiler GR, Nogueira RG. Carotid I's, L's and T's: collaterals shape the outcome of intracranial carotid occlusion in acute ischemic stroke. J Neurointerv Surg. 2015 Jun; 7(6):402-7. PMID: 24789707; PMCID: PMC4216639.
    16. Alexander MD, Meyers PM, English JD, Stradford TR, Sung S, Smith W, Halbach VV, Higashida RT, Dowd CF, Cooke DL, Hetts SW. Symptom differences and pretreatment asymptomatic interval affect outcomes of stenting for intracranial atherosclerotic disease. AJNR Am J Neuroradiol. 2014 Jun; 35(6):1157-62. PMID: 24676000.
      View in: PubMed
    17. Lima FO, Furie KL, Silva GS, Lev MH, Camargo EC, Singhal AB, Harris GJ, Halpern EF, Koroshetz WJ, Smith W, Nogueira RG. Prognosis of untreated strokes due to anterior circulation proximal intracranial arterial occlusions detected by use of computed tomography angiography. JAMA Neurol. 2014 Feb; 71(2):151-7. PMID: 24323077.
      View in: PubMed
    18. Saver JL, Jovin TG, Smith W, Albers GW, Baron JC, Boltze J, Broderick JP, Davis LA, Demchuk AM, DeSena S, Fiehler J, Gorelick PB, Hacke W, Holt B, Jahan R, Jing H, Khatri P, Kidwell CS, Lees KR, Lev MH, Liebeskind DS, Luby M, Lyden P, Megerian JT, Mocco J, Muir KW, Rowley HA, Ruedy RM, Savitz SI, Sipelis VJ, Shimp SK, Wechsler LR, Wintermark M, Wu O, Yavagal DR, Yoo AJ. Stroke treatment academic industry roundtable: research priorities in the assessment of neurothrombectomy devices. Stroke. 2013 Dec; 44(12):3596-601. PMID: 24193797; PMCID: PMC4142766.
    19. Flint AC, Faigeles BS, Cullen SP, Kamel H, Rao VA, Gupta R, Smith W, Bath PM, Donnan GA. THRIVE score predicts ischemic stroke outcomes and thrombolytic hemorrhage risk in VISTA. Stroke. 2013 Dec; 44(12):3365-9. PMID: 24072004.
      View in: PubMed
    20. Flint AC, Xiang B, Gupta R, Nogueira RG, Lutsep HL, Jovin TG, Albers GW, Liebeskind DS, Sanossian N, Smith W. THRIVE score predicts outcomes with a third-generation endovascular stroke treatment device in the TREVO-2 trial. Stroke. 2013 Dec; 44(12):3370-5. PMID: 24072003; PMCID: PMC4157913.
    21. González RG, Furie KL, Goldmacher GV, Smith W, Kamalian S, Payabvash S, Harris GJ, Halpern EF, Koroshetz WJ, Camargo EC, Dillon WP, Lev MH. Good outcome rate of 35% in IV-tPA-treated patients with computed tomography angiography confirmed severe anterior circulation occlusive stroke. Stroke. 2013 Nov; 44(11):3109-13. PMID: 24003051; PMCID: PMC4374554.
    22. Morgenstern LB, Smith W. Setting priorities for stroke care and research. Int J Stroke. 2013 Aug; 8(6):445-6. PMID: 23879748.
      View in: PubMed
    23. Zaidat OO, Castonguay AC, Fitzsimmons BF, Woodward BK, Wang Z, Killer-Oberpfalzer M, Wakhloo A, Gupta R, Kirshner H, Eliasziw M, Thomas Megerian J, Shetty S, Yoklavich Guilhermier M, Barnwell S, Smith W, Gress DR. Design of the Vitesse Intracranial Stent Study for Ischemic Therapy (VISSIT) trial in symptomatic intracranial stenosis. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):1131-9. PMID: 23261207.
      View in: PubMed
    24. Navi BB, Kamel H, Hemphill JC, Smith W. Trajectory of functional recovery after hospital discharge for subarachnoid hemorrhage. Neurocrit Care. 2012 Dec; 17(3):343-7. PMID: 22932992.
      View in: PubMed
    25. Kamel H, Navi BB, Elijovich L, Josephson SA, Yee AH, Fung G, Johnston SC, Smith W. Pilot randomized trial of outpatient cardiac monitoring after cryptogenic stroke. Stroke. 2013 Feb; 44(2):528-30. PMID: 23192756.
      View in: PubMed
    26. Kamel H, Patel N, Rao VA, Cullen SP, Faigeles BS, Smith W, Flint AC. The totaled health risks in vascular events (THRIVE) score predicts ischemic stroke outcomes independent of thrombolytic therapy in the NINDS tPA trial. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):1111-6. PMID: 23122722.
      View in: PubMed
    27. Moftakhar P, English JD, Cooke DL, Kim WT, Stout C, Smith W, Dowd CF, Higashida RT, Halbach VV, Hetts SW. Density of thrombus on admission CT predicts revascularization efficacy in large vessel occlusion acute ischemic stroke. Stroke. 2013 Jan; 44(1):243-5. PMID: 23111438.
      View in: PubMed
    28. Claassen J, Silbergleit R, Weingart SD, Smith W. Emergency neurological life support: status epilepticus. Neurocrit Care. 2012 Sep; 17 Suppl 1:S73-8. PMID: 22956118.
      View in: PubMed
    29. Stevens RD, Huff JS, Duckworth J, Papangelou A, Weingart SD, Smith W. Emergency neurological life support: intracranial hypertension and herniation. Neurocrit Care. 2012 Sep; 17 Suppl 1:S60-5. PMID: 22936079.
      View in: PubMed
    30. Gaieski DF, Nathan BR, Weingart SD, Smith W. Emergency neurologic life support: meningitis and encephalitis. Neurocrit Care. 2012 Sep; 17 Suppl 1:S66-72. PMID: 22961702.
      View in: PubMed
    31. Smith W, Weingart S. Emergency Neurological Life Support (ENLS): what to do in the first hour of a neurological emergency. Neurocrit Care. 2012 Sep; 17 Suppl 1:S1-3. PMID: 22843191.
      View in: PubMed
    32. Edlow JA, Samuels O, Smith W, Weingart SD. Emergency neurological life support: subarachnoid hemorrhage. Neurocrit Care. 2012 Sep; 17 Suppl 1:S47-53. PMID: 22932990.
      View in: PubMed
    33. Gross H, Sung G, Weingart SD, Smith W. Emergency neurological life support: acute ischemic stroke. Neurocrit Care. 2012 Sep; 17 Suppl 1:S29-36. PMID: 22948888.
      View in: PubMed
    34. Huff JS, Stevens RD, Weingart SD, Smith W. Emergency neurological life support: approach to the patient with coma. Neurocrit Care. 2012 Sep; 17 Suppl 1:S54-9. PMID: 22932989.
      View in: PubMed
    35. O'Phelan KH, Bunney EB, Weingart SD, Smith W. Emergency neurological life support: spinal cord compression (SCC). Neurocrit Care. 2012 Sep; 17 Suppl 1:S96-101. PMID: 22956117.
      View in: PubMed
    36. Rittenberger JC, Polderman KH, Smith W, Weingart SD. Emergency neurological life support: resuscitation following cardiac arrest. Neurocrit Care. 2012 Sep; 17 Suppl 1:S21-8. PMID: 22932988.
      View in: PubMed
    37. Seder DB, Riker RR, Jagoda A, Smith W, Weingart SD. Emergency neurological life support: airway, ventilation, and sedation. Neurocrit Care. 2012 Sep; 17 Suppl 1:S4-20. PMID: 22972019.
      View in: PubMed
    38. Stein DM, Roddy V, Marx J, Smith W, Weingart SD. Emergency neurological life support: traumatic spine injury. Neurocrit Care. 2012 Sep; 17 Suppl 1:S102-11. PMID: 22965323.
      View in: PubMed
    39. Andrews CM, Jauch EC, Hemphill JC, Smith W, Weingart SD. Emergency neurological life support: intracerebral hemorrhage. Neurocrit Care. 2012 Sep; 17 Suppl 1:S37-46. PMID: 22965322.
      View in: PubMed
    40. Swadron SP, LeRoux P, Smith W, Weingart SD. Emergency neurological life support: traumatic brain injury. Neurocrit Care. 2012 Sep; 17 Suppl 1:S112-21. PMID: 22975830.
      View in: PubMed
    41. Flower O, Bowles C, Wijdicks E, Weingart SD, Smith W. Emergency neurological life support: acute non-traumatic weakness. Neurocrit Care. 2012 Sep; 17 Suppl 1:S79-95. PMID: 22972018.
      View in: PubMed
    42. Flint AC, Kamel H, Rao VA, Cullen SP, Faigeles BS, Smith W. Validation of the Totaled Health Risks In Vascular Events (THRIVE) score for outcome prediction in endovascular stroke treatment. Int J Stroke. 2014 Jan; 9(1):32-9. PMID: 22928705.
      View in: PubMed
    43. Nogueira RG, Lutsep HL, Gupta R, Jovin TG, Albers GW, Walker GA, Liebeskind DS, Smith W. Trevo versus Merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial. Lancet. 2012 Oct 06; 380(9849):1231-40. PMID: 22932714; PMCID: PMC4176618.
    44. Wijdicks EF, Smith W. Brain death in children: why does it have to be so complicated? Ann Neurol. 2012 Apr; 71(4):442-3. PMID: 22522438.
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    45. Fields JD, Lutsep HL, Rymer MR, Budzik RF, Devlin TG, Baxter BW, Malek R, Padidar AM, Barnwell SL, Smith W. Endovascular mechanical thrombectomy for the treatment of acute ischemic stroke due to arterial dissection. Interv Neuroradiol. 2012 Mar; 18(1):74-9. PMID: 22440604; PMCID: PMC3312093.
    46. Toossi S, Lomen-Hoerth C, Josephson SA, Gropper MA, Roberts J, Patton K, Smith W. Organ donation after cardiac death in amyotrophic lateral sclerosis. Ann Neurol. 2012 Feb; 71(2):154-6. PMID: 22334377.
      View in: PubMed
    47. González RG, Lev MH, Goldmacher GV, Smith W, Payabvash S, Harris GJ, Halpern EF, Koroshetz WJ, Camargo EC, Dillon WP, Furie KL. Improved outcome prediction using CT angiography in addition to standard ischemic stroke assessment: results from the STOPStroke study. PLoS One. 2012; 7(1):e30352. PMID: 22276182; PMCID: PMC3262833.
    48. Smith W, Schwab S. Advances in stroke: critical care and emergency medicine. Stroke. 2012 Feb; 43(2):308-9. PMID: 22267827.
      View in: PubMed
    49. Navi BB, Kamel H, McCulloch CE, Nakagawa K, Naravetla B, Moheet AM, Wong C, Johnston SC, Hemphill JC, Smith W. Accuracy of neurovascular fellows' prognostication of outcome after subarachnoid hemorrhage. Stroke. 2012 Mar; 43(3):702-7. PMID: 22223238.
      View in: PubMed
    50. Nakagawa K, Smith W. Evaluation and management of increased intracranial pressure. Continuum (Minneap Minn). 2011 Oct; 17(5 Neurologic Consultation in the Hospital):1077-93. PMID: 22809983.
      View in: PubMed
    51. Fields JD, Lutsep HL, Smith W. Higher degrees of recanalization after mechanical thrombectomy for acute stroke are associated with improved outcome and decreased mortality: pooled analysis of the MERCI and Multi MERCI trials. AJNR Am J Neuroradiol. 2011 Dec; 32(11):2170-4. PMID: 21960499.
      View in: PubMed
    52. Nogueira RG, Smith W, Sung G, Duckwiler G, Walker G, Roberts R, Saver JL, Liebeskind DS. Effect of time to reperfusion on clinical outcome of anterior circulation strokes treated with thrombectomy: pooled analysis of the MERCI and Multi MERCI trials. Stroke. 2011 Nov; 42(11):3144-9. PMID: 21921278.
      View in: PubMed
    53. Kamel H, Smith W. Detection of atrial fibrillation and secondary stroke prevention using telemetry and ambulatory cardiac monitoring. Curr Atheroscler Rep. 2011 Aug; 13(4):338-43. PMID: 21499792.
      View in: PubMed
    54. Taub PR, Fields JD, Wu AH, Miss JC, Lawton MT, Smith W, Young WL, Zaroff JG, Ko NU. Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2011 Aug; 15(1):13-8. PMID: 21479679; PMCID: PMC3133817.
    55. Nakagawa K, Smith W. Paradoxical vasoconstrictive effect in the contralateral hemisphere after carotid stenting. Neurology. 2011 Jul 19; 77(3):300. PMID: 21768600.
      View in: PubMed
    56. Nahab F, Walker GA, Dion JE, Smith W. Safety of periprocedural heparin in acute ischemic stroke endovascular therapy: the multi MERCI trial. J Stroke Cerebrovasc Dis. 2012 Nov; 21(8):790-3. PMID: 21640610.
      View in: PubMed
    57. Boussel L, Rayz V, Martin A, Lawton M, Higashida R, Smith W, Young WL, Saloner D. Temporal stability of dysmorphic fusiform aneurysms of the intracranial internal carotid artery. J Vasc Interv Radiol. 2011 Jul; 22(7):1007-11. PMID: 21419648; PMCID: PMC3125409.
    58. Maas MB, Lev MH, Ay H, Singhal AB, Greer DM, Smith W, Harris GJ, Halpern EF, Koroshetz WJ, Furie KL. The prognosis for aphasia in stroke. J Stroke Cerebrovasc Dis. 2012 Jul; 21(5):350-7. PMID: 21185744; PMCID: PMC3117986.
    59. Poisson SN, Nguyen-Huynh MN, Johnston SC, Furie KL, Lev MH, Smith W. Intracranial large vessel occlusion as a predictor of decline in functional status after transient ischemic attack. Stroke. 2011 Jan; 42(1):44-7. PMID: 21106958.
      View in: PubMed
    60. Dhand A, Nakagawa K, Nagpal S, Gelfand JM, Kim AS, Smith W, Tihan T. Cardiac rupture after intravenous t-PA administration in acute ischemic stroke. Neurocrit Care. 2010 Oct; 13(2):261-2. PMID: 20697837.
      View in: PubMed
    61. Lima FO, Furie KL, Silva GS, Lev MH, Camargo EC, Singhal AB, Harris GJ, Halpern EF, Koroshetz WJ, Smith W, Yoo AJ, Nogueira RG. The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion. Stroke. 2010 Oct; 41(10):2316-22. PMID: 20829514; PMCID: PMC4939434.
    62. Silva GS, Lima FO, Camargo EC, Smith W, Lev MH, Harris GJ, Halpern EF, Koroshetz W, Furie KL. Gender differences in outcomes after ischemic stroke: role of ischemic lesion volume and intracranial large-artery occlusion. Cerebrovasc Dis. 2010; 30(5):470-5. PMID: 20733301; PMCID: PMC2992642.
    63. Josephson SA, Moheet AM, Gropper MA, Nichols AD, Smith W. Ventilator-associated pneumonia in a neurologic intensive care unit does not lead to increased mortality. Neurocrit Care. 2010 Apr; 12(2):155-8. PMID: 19806474.
      View in: PubMed
    64. Furtado AD, Adraktas DD, Brasic N, Cheng SC, Ordovas K, Smith W, Lewin MR, Chun K, Chien JD, Schaeffer S, Wintermark M. The triple rule-out for acute ischemic stroke: imaging the brain, carotid arteries, aorta, and heart. AJNR Am J Neuroradiol. 2010 Aug; 31(7):1290-6. PMID: 20360341.
      View in: PubMed
    65. Josephson SA, Douglas VC, Lawton MT, English JD, Smith W, Ko NU. Improvement in intensive care unit outcomes in patients with subarachnoid hemorrhage after initiation of neurointensivist co-management. J Neurosurg. 2010 Mar; 112(3):626-30. PMID: 19731990.
      View in: PubMed
    66. Silva GS, Lima FO, Camargo EC, Smith W, Singhal AB, Greer DM, Ay H, Lev MH, Harris GJ, Halpern EF, Sonni S, Koroshetz W, Furie KL. Wake-up stroke: clinical and neuroimaging characteristics. Cerebrovasc Dis. 2010; 29(4):336-42. PMID: 20130399; PMCID: PMC2914433.
    67. Lima FO, Lev MH, Levy RA, Silva GS, Ebril M, de Camargo EC, Pomerantz S, Singhal AB, Greer DM, Ay H, González RG, Koroshetz WJ, Smith W, Furie KL. Functional contrast-enhanced CT for evaluation of acute ischemic stroke does not increase the risk of contrast-induced nephropathy. AJNR Am J Neuroradiol. 2010 May; 31(5):817-21. PMID: 20044502; PMCID: PMC2873111.
    68. Furtado AD, Lau BC, Vittinghoff E, Dillon WP, Smith W, Rigby T, Boussel L, Wintermark M. Optimal brain perfusion CT coverage in patients with acute middle cerebral artery stroke. AJNR Am J Neuroradiol. 2010 Apr; 31(4):691-5. PMID: 19942712.
      View in: PubMed
    69. Soares BP, Tong E, Hom J, Cheng SC, Bredno J, Boussel L, Smith W, Wintermark M. Reperfusion is a more accurate predictor of follow-up infarct volume than recanalization: a proof of concept using CT in acute ischemic stroke patients. Stroke. 2010 Jan; 41(1):e34-40. PMID: 19910542; PMCID: PMC2909663.
    70. Nogueira RG, Smith W. Emergency treatment of acute ischemic stroke: expanding the time window. Curr Treat Options Neurol. 2009 Nov; 11(6):433-43. PMID: 19891906.
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    71. Nogueira RG, Liebeskind DS, Sung G, Duckwiler G, Smith W. Predictors of good clinical outcomes, mortality, and successful revascularization in patients with acute ischemic stroke undergoing thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI Trials. Stroke. 2009 Dec; 40(12):3777-83. PMID: 19875740.
      View in: PubMed
    72. Smith W, Lev MH, English JD, Camargo EC, Chou M, Johnston SC, Gonzalez G, Schaefer PW, Dillon WP, Koroshetz WJ, Furie KL. Significance of large vessel intracranial occlusion causing acute ischemic stroke and TIA. Stroke. 2009 Dec; 40(12):3834-40. PMID: 19834014; PMCID: PMC2796543.
    73. Maas MB, Furie KL, Lev MH, Ay H, Singhal AB, Greer DM, Harris GJ, Halpern E, Koroshetz WJ, Smith W. National Institutes of Health Stroke Scale score is poorly predictive of proximal occlusion in acute cerebral ischemia. Stroke. 2009 Sep; 40(9):2988-93. PMID: 19608992; PMCID: PMC2763301.
    74. Maas MB, Lev MH, Ay H, Singhal AB, Greer DM, Smith W, Harris GJ, Halpern E, Kemmling A, Koroshetz WJ, Furie KL. Collateral vessels on CT angiography predict outcome in acute ischemic stroke. Stroke. 2009 Sep; 40(9):3001-5. PMID: 19590055; PMCID: PMC2754152.
    75. Smith W, Fetz EE. Synaptic linkages between corticomotoneuronal cells affecting forelimb muscles in behaving primates. J Neurophysiol. 2009 Aug; 102(2):1040-8. PMID: 19515946; PMCID: PMC2724364.
    76. Smith W, Fetz EE. Synaptic interactions between forelimb-related motor cortex neurons in behaving primates. J Neurophysiol. 2009 Aug; 102(2):1026-39. PMID: 19439672; PMCID: PMC2724363.
    77. Elijovich L, Josephson SA, Fung GL, Smith W. Intermittent atrial fibrillation may account for a large proportion of otherwise cryptogenic stroke: a study of 30-day cardiac event monitors. J Stroke Cerebrovasc Dis. 2009 May-Jun; 18(3):185-9. PMID: 19426887.
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    78. Boussel L, Rayz V, Martin A, Acevedo-Bolton G, Lawton MT, Higashida R, Smith W, Young WL, Saloner D. Phase-contrast magnetic resonance imaging measurements in intracranial aneurysms in vivo of flow patterns, velocity fields, and wall shear stress: comparison with computational fluid dynamics. Magn Reson Med. 2009 Feb; 61(2):409-17. PMID: 19161132; PMCID: PMC3055272.
    79. Ho EL, Josephson SA, Lee HS, Smith W. Cerebrovascular complications of methamphetamine abuse. Neurocrit Care. 2009; 10(3):295-305. PMID: 19132558.
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    80. Nogueira RG, Smith W. Safety and efficacy of endovascular thrombectomy in patients with abnormal hemostasis: pooled analysis of the MERCI and multi MERCI trials. Stroke. 2009 Feb; 40(2):516-22. PMID: 19095994.
      View in: PubMed
    81. Goldmakher GV, Camargo EC, Furie KL, Singhal AB, Roccatagliata L, Halpern EF, Chou MJ, Biagini T, Smith W, Harris GJ, Dillon WP, Gonzalez RG, Koroshetz WJ, Lev MH. Hyperdense basilar artery sign on unenhanced CT predicts thrombus and outcome in acute posterior circulation stroke. Stroke. 2009 Jan; 40(1):134-9. PMID: 19038918.
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    82. Josephson SA, Saver JL, Smith W. Comparison of mechanical embolectomy and intraarterial thrombolysis in acute ischemic stroke within the MCA: MERCI and Multi MERCI compared to PROACT II. Neurocrit Care. 2009; 10(1):43-9. PMID: 19030784.
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    83. Furtado AD, Smith W, Koroshetz W, Dillon WP, Furie KL, Lev MH, Vittinghoff E, Schaeffer S, Biagini T, Hazarika O, Wintermark M. Perfusion CT Imaging Follows Clinical Severity in Left Hemispheric Strokes. Eur Neurol. 2008; 60(5):244-52. PMID: 18756089.
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    84. Boussel L, Rayz V, McCulloch C, Martin A, Acevedo-Bolton G, Lawton M, Higashida R, Smith W, Young WL, Saloner D. Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study. Stroke. 2008 Nov; 39(11):2997-3002. PMID: 18688012; PMCID: PMC2661849.
    85. Wintermark M, Dillon WP, Smith W, Lau BC, Chaudhary S, Liu S, Yu M, Fitch M, Chien JD, Higashida RT, Ko NU. Visual grading system for vasospasm based on perfusion CT imaging: comparisons with conventional angiography and quantitative perfusion CT. Cerebrovasc Dis. 2008; 26(2):163-70. PMID: 18560220.
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    86. Kamath A, Smith W, Powers WJ, Cianfoni A, Chien JD, Videen T, Lawton MT, Finley B, Dillon WP, Wintermark M. Perfusion CT compared to H(2) (15)O/O (15)O PET in patients with chronic cervical carotid artery occlusion. Neuroradiology. 2008 Sep; 50(9):745-51. PMID: 18509627; PMCID: PMC2586154.
    87. Mathews MS, Smith W, Wintermark M, Dillon WP, Binder DK. Local cortical hypoperfusion imaged with CT perfusion during postictal Todd's paresis. Neuroradiology. 2008 May; 50(5):397-401. PMID: 18278489.
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    88. Singh V, Smith W, Lawton MT, Halbach VV, Young WL. Risk factors for hemorrhagic presentation in patients with dural arteriovenous fistulae. Neurosurgery. 2008 Mar; 62(3):628-35; discussion 628-35. PMID: 18425010.
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    89. Smith W, Sung G, Saver J, Budzik R, Duckwiler G, Liebeskind DS, Lutsep HL, Rymer MM, Higashida RT, Starkman S, Gobin YP, Frei D, Grobelny T, Hellinger F, Huddle D, Kidwell C, Koroshetz W, Marks M, Nesbit G, Silverman IE. Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke. 2008 Apr; 39(4):1205-12. PMID: 18309168.
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    90. Ko NU, Rajendran P, Kim H, Rutkowski M, Pawlikowska L, Kwok PY, Higashida RT, Lawton MT, Smith W, Zaroff JG, Young WL. Endothelial nitric oxide synthase polymorphism (-786T->C) and increased risk of angiographic vasospasm after aneurysmal subarachnoid hemorrhage. Stroke. 2008 Apr; 39(4):1103-8. PMID: 18309169; PMCID: PMC2650384.
    91. Nguyen-Huynh MN, Wintermark M, English J, Lam J, Vittinghoff E, Smith W, Johnston SC. How accurate is CT angiography in evaluating intracranial atherosclerotic disease? Stroke. 2008 Apr; 39(4):1184-8. PMID: 18292376.
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    92. Chaudhary SR, Ko N, Dillon WP, Yu MB, Liu S, Criqui GI, Higashida RT, Smith W, Wintermark M. Prospective evaluation of multidetector-row CT angiography for the diagnosis of vasospasm following subarachnoid hemorrhage: a comparison with digital subtraction angiography. Cerebrovasc Dis. 2008; 25(1-2):144-50. PMID: 18073468.
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    93. Kim J, Smith A, Hemphill JC, Smith W, Lu Y, Dillon WP, Wintermark M. Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage. AJNR Am J Neuroradiol. 2008 Mar; 29(3):520-5. PMID: 18065505.
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    94. Boussel L, Wintermark M, Martin A, Dispensa B, VanTijen R, Leach J, Rayz V, Acevedo-Bolton G, Lawton M, Higashida R, Smith W, Young WL, Saloner D. Monitoring serial change in the lumen and outer wall of vertebrobasilar aneurysms. AJNR Am J Neuroradiol. 2008 Feb; 29(2):259-64. PMID: 17974611.
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    95. Camargo EC, Furie KL, Singhal AB, Roccatagliata L, Cunnane ME, Halpern EF, Harris GJ, Smith W, Gonzalez RG, Koroshetz WJ, Lev MH. Acute brain infarct: detection and delineation with CT angiographic source images versus nonenhanced CT scans. Radiology. 2007 Aug; 244(2):541-8. PMID: 17581888.
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    96. Tan JC, Dillon WP, Liu S, Adler F, Smith W, Wintermark M. Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients. Ann Neurol. 2007 Jun; 61(6):533-43. PMID: 17431875.
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    97. Flint AC, Duckwiler GR, Budzik RF, Liebeskind DS, Smith W. Mechanical thrombectomy of intracranial internal carotid occlusion: pooled results of the MERCI and Multi MERCI Part I trials. Stroke. 2007 Apr; 38(4):1274-80. PMID: 17332445.
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    98. Smith W. Intra-arterial thrombolytic therapy for acute basilar occlusion: pro. Stroke. 2007 Feb; 38(2 Suppl):701-3. PMID: 17261720.
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    99. Smith W. Technology Insight: recanalization with drugs and devices during acute ischemic stroke. Nat Clin Pract Neurol. 2007 Jan; 3(1):45-53. PMID: 17205074.
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    100. Smith W. Can emergency medicine physicians accurately identify i.v. t-PA eligible acute stroke patients? Neurocrit Care. 2007; 7(2):101-2. PMID: 17710377.
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    101. Smith W. Safety of mechanical thrombectomy and intravenous tissue plasminogen activator in acute ischemic stroke. Results of the multi Mechanical Embolus Removal in Cerebral Ischemia (MERCI) trial, part I. AJNR Am J Neuroradiol. 2006 Jun-Jul; 27(6):1177-82. PMID: 16775259.
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    102. Johnston SC, Rootenberg JD, Katrak S, Smith W, Elkins JS. Effect of a US National Institutes of Health programme of clinical trials on public health and costs. Lancet. 2006 Apr 22; 367(9519):1319-27. PMID: 16631910.
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    103. Yarlagadda S, Rajendran P, Miss JC, Banki NM, Kopelnik A, Wu AH, Ko N, Gelb AW, Lawton MT, Smith W, Young WL, Zaroff JG. Cardiovascular predictors of in-patient mortality after subarachnoid hemorrhage. Neurocrit Care. 2006; 5(2):102-7. PMID: 17099255.
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    104. Fisher LA, Ko N, Miss J, Tung PP, Kopelnik A, Banki NM, Gardner D, Smith W, Lawton MT, Zaroff JG. Hypernatremia predicts adverse cardiovascular and neurological outcomes after SAH. Neurocrit Care. 2006; 5(3):180-5. PMID: 17290085.
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    105. Smith W, Tsao JW, Billings ME, Johnston SC, Hemphill JC, Bonovich DC, Dillon WP. Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia. Neurocrit Care. 2006; 4(1):14-7. PMID: 16498189.
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    106. Kothavale A, Banki NM, Kopelnik A, Yarlagadda S, Lawton MT, Ko N, Smith W, Drew B, Foster E, Zaroff JG. Predictors of left ventricular regional wall motion abnormalities after subarachnoid hemorrhage. Neurocrit Care. 2006; 4(3):199-205. PMID: 16757824.
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    107. Wintermark M, Ko NU, Smith W, Liu S, Higashida RT, Dillon WP. Vasospasm after subarachnoid hemorrhage: utility of perfusion CT and CT angiography on diagnosis and management. AJNR Am J Neuroradiol. 2006 Jan; 27(1):26-34. PMID: 16418351.
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    108. Ay H, Furie KL, Singhal A, Smith W, Sorensen AG, Koroshetz WJ. An evidence-based causative classification system for acute ischemic stroke. Ann Neurol. 2005 Nov; 58(5):688-97. PMID: 16240340.
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    109. Smith W, Mapstone M. Does extracorporeal circulation harm the brain? Neurology. 2005 Oct 11; 65(7):978-9. PMID: 16217045.
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    110. Tsao JW, Hemphill JC, Johnston SC, Smith W, Bonovich DC. Initial Glasgow Coma Scale score predicts outcome following thrombolysis for posterior circulation stroke. Arch Neurol. 2005 Jul; 62(7):1126-9. PMID: 16009770.
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    111. Smith W, Sung G, Starkman S, Saver JL, Kidwell CS, Gobin YP, Lutsep HL, Nesbit GM, Grobelny T, Rymer MM, Silverman IE, Higashida RT, Budzik RF, Marks MP. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke. 2005 Jul; 36(7):1432-8. PMID: 15961709.
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    112. Josephson SA, Dillon WP, Smith W. Incidence of contrast nephropathy from cerebral CT angiography and CT perfusion imaging. Neurology. 2005 May 24; 64(10):1805-6. PMID: 15911820.
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    113. Hemphill JC, Smith W, Sonne DC, Morabito D, Manley GT. Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results. AJNR Am J Neuroradiol. 2005 May; 26(5):1095-100. PMID: 15891166.
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    114. Yu W, Smith W, Singh V, Ko NU, Cullen SP, Dowd CF, Halbach VV, Higashida RT. Long-term outcome of endovascular stenting for symptomatic basilar artery stenosis. Neurology. 2005 Mar 22; 64(6):1055-7. PMID: 15781826.
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    115. Ko NU, Achrol AS, Chopra M, Saha M, Gupta D, Smith W, Higashida RT, Young WL. Cerebral blood flow changes after endovascular treatment of cerebrovascular stenoses. AJNR Am J Neuroradiol. 2005 Mar; 26(3):538-42. PMID: 15760862.
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    116. Kopelnik A, Fisher L, Miss JC, Banki N, Tung P, Lawton MT, Ko N, Smith W, Drew B, Foster E, Zaroff J. Prevalence and implications of diastolic dysfunction after subarachnoid hemorrhage. Neurocrit Care. 2005; 3(2):132-8. PMID: 16174882.
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    117. Wintermark M, Fischbein NJ, Smith W, Ko NU, Quist M, Dillon WP. Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke. AJNR Am J Neuroradiol. 2005 Jan; 26(1):104-12. PMID: 15661711.
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    118. Miss JC, Kopelnik A, Fisher LA, Tung PP, Banki NM, Lawton MT, Smith W, Dowd CF, Zaroff JG. Cardiac injury after subarachnoid hemorrhage is independent of the type of aneurysm therapy. Neurosurgery. 2004 Dec; 55(6):1244-50; discussion 1250-1. PMID: 15574206.
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    119. Smith W, Dowd CF, Johnston SC, Ko NU, DeArmond SJ, Dillon WP, Setty D, Lawton MT, Young WL, Higashida RT, Halbach VV. Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Stroke. 2004 Nov; 35(11):2518-22. PMID: 15472097.
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    120. Josephson SA, Bryant SO, Mak HK, Johnston SC, Dillon WP, Smith W. Evaluation of carotid stenosis using CT angiography in the initial evaluation of stroke and TIA. Neurology. 2004 Aug 10; 63(3):457-60. PMID: 15304575.
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    121. Wintermark M, Smith W, Ko NU, Quist M, Schnyder P, Dillon WP. Dynamic perfusion CT: optimizing the temporal resolution and contrast volume for calculation of perfusion CT parameters in stroke patients. AJNR Am J Neuroradiol. 2004 May; 25(5):720-9. PMID: 15140710.
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    122. Bardach NS, Olson SJ, Elkins JS, Smith W, Lawton MT, Johnston SC. Regionalization of treatment for subarachnoid hemorrhage: a cost-utility analysis. Circulation. 2004 May 11; 109(18):2207-12. PMID: 15117848.
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    123. Smith W. Pathophysiology of focal cerebral ischemia: a therapeutic perspective. J Vasc Interv Radiol. 2004 Jan; 15(1 Pt 2):S3-12. PMID: 15101511.
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    124. Josephson SA, Dillon WP, Dowd CF, Malek R, Lawton MT, Smith W. Continuous bleeding from a basilar terminus aneurysm imaged with CT angiography and conventional angiography. Neurocrit Care. 2004; 1(1):103-6. PMID: 16174904.
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    125. Yu W, Binder D, Foster-Barber A, Malek R, Smith W, Higashida RT. Endovascular embolectomy of acute basilar artery occlusion. Neurology. 2003 Nov 25; 61(10):1421-3. PMID: 14638968.
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    126. Smith W, Mindelzun RE, Miller B. Simultanagnosia through the eyes of an artist. Neurology. 2003 Jun 10; 60(11):1832-4. PMID: 12796543.
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    127. Smith W, Johnston SC, Skalabrin EJ, Weaver M, Azari P, Albers GW, Gress DR. Spinal manipulative therapy is an independent risk factor for vertebral artery dissection. Neurology. 2003 May 13; 60(9):1424-8. PMID: 12743225.
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    128. Wechsler LR, Roberts R, Furlan AJ, Higashida RT, Dillon W, Roberts H, Rowley HA, Pettigrew LC, Callahan AS, Bruno A, Fayad P, Smith W, Firszt CM, Schulz GA. Factors influencing outcome and treatment effect in PROACT II. Stroke. 2003 May; 34(5):1224-9. PMID: 12677011.
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    129. Smith W, Roberts HC, Chuang NA, Ong KC, Lee TJ, Johnston SC, Dillon WP. Safety and feasibility of a CT protocol for acute stroke: combined CT, CT angiography, and CT perfusion imaging in 53 consecutive patients. AJNR Am J Neuroradiol. 2003 Apr; 24(4):688-90. PMID: 12695204.
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    130. Fullerton HJ, Chetkovich DM, Wu YW, Smith W, Johnston SC. Deaths from stroke in US children, 1979 to 1998. Neurology. 2002 Jul 09; 59(1):34-9. PMID: 12105304.
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    131. Gress DR, Smith W, Dowd CF, Van Halbach V, Finley RJ, Higashida RT. Angioplasty for intracranial symptomatic vertebrobasilar ischemia. Neurosurgery. 2002 Jul; 51(1):23-7; discussion 27-9. PMID: 12182423.
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    132. Fullerton HJ, Johnston SC, Smith W. Arterial dissection and stroke in children. Neurology. 2001 Oct 09; 57(7):1155-60. PMID: 11601431.
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    133. Singh V, Meyers PM, Halbach VH, Gress DR, Higashida RT, Dowd CF, Smith W. Dural arteriovenous fistula associated with prothrombin gene mutation. J Neuroimaging. 2001 Jul; 11(3):319-21. PMID: 11462303.
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    134. Roberts HC, Roberts TP, Smith W, Lee TJ, Fischbein NJ, Dillon WP. Multisection dynamic CT perfusion for acute cerebral ischemia: the "toggling-table" technique. AJNR Am J Neuroradiol. 2001 Jun-Jul; 22(6):1077-80. PMID: 11415901.
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    135. Johnston SC, Fung LH, Gillum LA, Smith W, Brass LM, Lichtman JH, Brown AN. Utilization of intravenous tissue-type plasminogen activator for ischemic stroke at academic medical centers: the influence of ethnicity. Stroke. 2001 May; 32(5):1061-8. PMID: 11340210.
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    136. Malek AM, Higashida RT, Phatouros CC, Lempert TE, Meyers PM, Smith W, Dowd CF, Halbach VV. Stent angioplasty for cervical carotid artery stenosis in high-risk symptomatic NASCET-ineligible patients. Stroke. 2000 Dec; 31(12):3029-33. PMID: 11108767.
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    137. Malek AM, Higashida RT, Phatouros CC, Lempert TE, Meyers PM, Smith W, Dowd CF, Halbach VV. Endovascular management of extracranial carotid artery dissection achieved using stent angioplasty. AJNR Am J Neuroradiol. 2000 Aug; 21(7):1280-92. PMID: 10954281.
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    138. Malek AM, Higashida RT, Halbach VV, Dowd CF, Phatouros CC, Lempert TE, Meyers PM, Smith W, Stoney R. Patient presentation, angiographic features, and treatment of strangulation-induced bilateral dissection of the cervical internal carotid artery. Report of three cases. J Neurosurg. 2000 Mar; 92(3):481-7. PMID: 10701540.
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    139. Roberts HC, Dillon WP, Smith W. Dynamic CT perfusion to assess the effect of carotid revascularization in chronic cerebral ischemia. AJNR Am J Neuroradiol. 2000 Feb; 21(2):421-5. PMID: 10696034.
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    140. Malek AM, Higashida RT, Reilly LM, Smith W, Kang SM, Gress DR, Meyers PM, Phatouros CC, Halbach VV, Dowd CF. Subclavian arteritis and pseudoaneurysm formation secondary to stent infection. Cardiovasc Intervent Radiol. 2000 Jan-Feb; 23(1):57-60. PMID: 10656908.
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    141. Porteous GH, Corry MD, Smith W. Emergency medical services dispatcher identification of stroke and transient ischemic attack. Prehosp Emerg Care. 1999 Jul-Sep; 3(3):211-6. PMID: 10424858.
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    142. Smith W, Corry MD, Fazackerley J, Isaacs SM. Improved paramedic sensitivity in identifying stroke victims in the prehospital setting. Prehosp Emerg Care. 1999 Jul-Sep; 3(3):207-10. PMID: 10424857.
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    143. Phatouros CC, Higashida RT, Malek AM, Smith W, Dowd CF, Halbach VV. Embolization of the meningohypophyseal trunk as a cause of diabetes insipidus. AJNR Am J Neuroradiol. 1999 Jun-Jul; 20(6):1115-8. PMID: 10445454.
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    144. Malek AM, Higashida RT, Balousek PA, Phatouros CC, Smith W, Dowd CF, Halbach VV. Endovascular recanalization with balloon angioplasty and stenting of an occluded occipital sinus for treatment of intracranial venous hypertension: technical case report. Neurosurgery. 1999 Apr; 44(4):896-901. PMID: 10201320.
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    145. Phatouros CC, Higashida RT, Malek AM, Smith W, Mully TW, DeArmond SJ, Dowd CF, Halbach VV. Endovascular stenting of an acutely thrombosed basilar artery: technical case report and review of the literature. Neurosurgery. 1999 Mar; 44(3):667-73. PMID: 10069607.
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    146. Johnston SC, Smith W. Practice variability in management of transient ischemic attacks. Eur Neurol. 1999; 42(2):105-8. PMID: 10473982.
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    147. Smith W, Isaacs M, Corry MD. Accuracy of paramedic identification of stroke and transient ischemic attack in the field. Prehosp Emerg Care. 1998 Jul-Sep; 2(3):170-5. PMID: 9672689.
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    148. Johnston SC, Halbach VV, Smith W, Gress DR. Rapid development of giant fusiform cerebral aneurysms in angiographically normal vessels. Neurology. 1998 Apr; 50(4):1163-6. PMID: 9566418.
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    149. Hemphill JC, Smith W, Halbach VV. Neurologic manifestations of spinal epidural arteriovenous malformations. Neurology. 1998 Mar; 50(3):817-9. PMID: 9521288.
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    150. Smith W, Matthay MA. Evidence for a hydrostatic mechanism in human neurogenic pulmonary edema. Chest. 1997 May; 111(5):1326-33. PMID: 9149590.
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    151. Smith W, Messing RO. Cerebral aneurysm presenting as cough headache. Headache. 1993 Apr; 33(4):203-4. PMID: 8496059.
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