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Ethan Weiss, MD

Title(s)Associate Professor, Cardiovascular Research Inst
SchoolSchool of Medicine
ORCID ORCID Icon0000-0001-9936-5816 Additional info
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    University of California, San FranciscoClinical Fellowship School of Medicine - Cardiology
    Johns Hopkins UniversityM.D.1996School of Medicine

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    CLINICAL INTERESTS: Dr. Ethan Weiss is a cardiologist specializing in general cardiology. His special interests include preventive cardiology, genetics of coronary disease, risk assessment, and heart disease in the young.



    RESEARCH INTERESTS: In his research, Dr. Weiss uses genetic models to better understand the mechanism of metabolic disorders such as obesity, fatty liver disease, and diabetes. He also studies the blood clotting system and has interest in identifying novel ways to safely block clots associated with diseases such as heart attack and stroke without causing an increase in bleeding.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial. JAMA Intern Med. 2020 Sep 28. Lowe DA, Wu N, Rohdin-Bibby L, Moore AH, Kelly N, Liu YE, Philip E, Vittinghoff E, Heymsfield SB, Olgin JE, Shepherd JA, Weiss EJ. PMID: 32986097.
      View in: PubMed   Mentions:    Fields:    
    2. Comparing the Keyto App and Device with Weight Watchers' WW App for Weight Loss: Protocol for a Randomized Trial. JMIR Res Protoc. 2020 Aug 17; 9(8):e19053. Locke SR, Falkenhain K, Lowe DA, Lee T, Singer J, Weiss EJ, Little JP. PMID: 32804087.
      View in: PubMed   Mentions:
    3. Diet Quality and Visceral Adiposity Among a Multiethnic Population of Young, Middle and Older Aged Adults. Current Developments in Nutrition. 2020 Jun 1; 4(6):nzaa090-. Chloe E Panizza, Michael C Wong, Nisa Kelly, Yong En Liu, Yurii B Shvetsov, Dylan A Lowe, Ethan J Weiss, Steven B Heymsfield, Samantha Kennedy, Carol J Boushey, Gertraud Maskarinec, John A Shepherd. .
      View in: Publisher Site   Mentions:
    4. Diet Quality and Visceral Adiposity among a Multiethnic Population of Young, Middle, and Older Aged Adults. Current Developments in Nutrition. 2020; 4(6). Panizza, Chloe E Wong, Michael C Kelly, Nisa Liu, Yong En Shvetsov, Yurii B Lowe, Dylan A Weiss, Ethan J Heymsfield, Steven B Kennedy, Samantha Boushey, Carol J Maskarinec, Gertraud Shepherd, John A. View Publication.
    5. MON-LB107 Treat: A Randomized Controlled Trial Examining the Effects of Time Restricted Eating on Weight Loss and Metabolic Markers. Journal of the Endocrine Society. 2020 May 8; 4(Suppl 1). Dylan A Lowe, Ethan James Weiss, Jeffrey E Olgin, Eric Vittinghoff, John A Shepherd, Steven B Heymsfield, Linnea Rohdin-Bibby, Nisa Kelly, Nancy Wu. .
      View in: Publisher Site   Mentions:
    6. Billy Idol. Perspect Biol Med. 2020; 63(1):66-72. Weiss EJ. PMID: 32063587.
      View in: PubMed   Mentions:    Fields:    
    7. Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma. JCI Insight. 2019 08 08; 5. Corbit KC, Wilson CG, Lowe D, Tran JL, Vera NB, Clasquin M, Mattis AN, Weiss EJ. PMID: 31393852.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. Diabetes. 2018 02; 67(2):208-221. Corbit KC, Camporez JPG, Edmunds LR, Tran JL, Vera NB, Erion DM, Deo RC, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ. PMID: 29203511.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    9. Growth hormone receptor antagonism with pegvisomant in insulin resistant non-diabetic men: A phase II pilot study. F1000Res. 2017; 6:614. Lee AP, Mulligan K, Schambelan M, Murphy EJ, Weiss EJ. PMID: 28713554.
      View in: PubMed   Mentions:    Fields:    
    10. Adipocyte JAK2 mediates growth hormone-induced hepatic insulin resistance. JCI Insight. 2017 02 09; 2(3):e91001. Corbit KC, Camporez JPG, Tran JL, Wilson CG, Lowe DA, Nordstrom SM, Ganeshan K, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ. PMID: 28194444.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    11. Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice. Endocrinology. 2016 Feb; 157(2):570-85. Wilson CG, Tran JL, Erion DM, Vera NB, Febbraio M, Weiss EJ. PMID: 26650570.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    12. Disruption of JAK2 in adipocytes impairs lipolysis and improves fatty liver in mice with elevated GH. Mol Endocrinol. 2013 Aug; 27(8):1333-42. Nordstrom SM, Tran JL, Sos BC, Wagner KU, Weiss EJ. PMID: 23782652.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    13. HIV infection is associated with decreased thrombin generation. Clin Infect Dis. 2012 Apr; 54(8):1196-203. Hsue PY, Scherzer R, Grunfeld C, Nordstrom SM, Schnell A, Kohl LP, Nitta E, Martin JN, Deeks SG, Weiss EJ. PMID: 22438347.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    14. Liver-derived IGF-I contributes to GH-dependent increases in lean mass and bone mineral density in mice with comparable levels of circulating GH. Mol Endocrinol. 2011 Jul; 25(7):1223-30. Nordstrom SM, Tran JL, Sos BC, Wagner KU, Weiss EJ. PMID: 21527499.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    15. Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2. J Clin Invest. 2011 Apr; 121(4):1412-23. Sos BC, Harris C, Nordstrom SM, Tran JL, Balázs M, Caplazi P, Febbraio M, Applegate MA, Wagner KU, Weiss EJ. PMID: 21364286.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    16. Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development. Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12):2372-84. Williams MS, Weiss EJ, Sabatine MS, Simon DI, Bahou WF, Becker LC, Parise LV, Dauerman HL, French PA, Smyth SS, Becker RC. PMID: 21084706.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    17. Increased thrombosis susceptibility and altered fibrin formation in STAT5-deficient mice. Blood. 2010 Dec 16; 116(25):5724-33. Nordstrom SM, Holliday BA, Sos BC, Smyth JW, Levy RE, Dukes JW, Lord ST, Weiss EJ. PMID: 20823455.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. A Novel Tissue Factor Resistance Locus on Mouse Chromosome 11 Confers Protection from Thrombosis through Reduced Activity of Factor XI. Blood. 2008 Nov 16; 112(11):393-393. Katelyn M Dow, Sarah M Nordstrom, Brandon C Sos, Richard C Davis, Aldons J Lusis, Ethan J Weiss. .
      View in: Publisher Site   Mentions:
    19. Increased Thrombosis in Vivo and Altered Coagulation in Vitro in STAT5AB-Deficient Mice. Blood. 2008 Nov 16; 112(11):392-392. Sarah M Nordstrom, Brandon C Sos, Katelyn M Dow, Tina S Fong, Robert E Levy, Jonathan Dukes, Ethan J Weiss. .
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    20. Sex differences in thrombosis. Expert Rev Hematol. 2008 Oct; 1(1):3-8. Nordstrom SM, Weiss EJ. PMID: 21083002.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns. J Clin Invest. 2008 Aug; 118(8):2969-78. Wong JH, Dukes J, Levy RE, Sos B, Mason SE, Fong TS, Weiss EJ. PMID: 18618017.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    22. Increased Thrombosis in Male Versus Female Mice Is Mediated by Pulsatile Growth Hormone Secretion Possibly through Inhibition of TFPI Expression in the Vasculature. Blood. 2007 Nov 16; 110(11):266-266. Joshua H. Wong, Robert E. Levy, Jonathan Dukes, Sara A. Mason, Brandon Sos, Ethan J. Weiss. .
      View in: Publisher Site   Mentions:
    23. Protection against thrombosis in mice lacking PAR3. Blood. 2002 Nov 01; 100(9):3240-4. Weiss EJ, Hamilton JR, Lease KE, Coughlin SR. PMID: 12384423.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    24. Role of thrombin signalling in platelets in haemostasis and thrombosis. Nature. 2001 Sep 06; 413(6851):74-8. Sambrano GR, Weiss EJ, Zheng YW, Huang W, Coughlin SR. PMID: 11544528.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    25. Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin. J Biol Chem. 2000 Aug 18; 275(33):25216-21. Shapiro MJ, Weiss EJ, Faruqi TR, Coughlin SR. PMID: 10837487.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    26. Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. Determinants of specificity and utility in assays of receptor function. J Biol Chem. 2000 Jun 30; 275(26):19728-34. Faruqi TR, Weiss EJ, Shapiro MJ, Huang W, Coughlin SR. PMID: 10779527.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    27. PAR3 is a cofactor for PAR4 activation by thrombin. Nature. 2000 Apr 06; 404(6778):609-13. Nakanishi-Matsui M, Zheng YW, Sulciner DJ, Weiss EJ, Ludeman MJ, Coughlin SR. PMID: 10766244.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    28. Higher prevalence of GPIIIa PlA2 polymorphism in siblings of patients with premature coronary heart disease. Arch Pathol Lab Med. 1999 Dec; 123(12):1223-9. Goldschmidt-Clermont PJ, Coleman LD, Pham YM, Cooke GE, Shear WS, Weiss EJ, Kral BG, Moy TF, Yook RM, Blumenthal RS, Becker DM, Becker LC, Bray PF. PMID: 10583927.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. PlA1/A2 polymorphism of platelet glycoprotein IIIa and risk of cardiovascular disease. Lancet. 1997 Apr 12; 349(9058):1100-1. Bray PF, Weiss EJ, Tayback M, Goldschmidt-Clermont PJ. PMID: 9107268.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Self-expanding metal stent for obstructing adenocarcinoma of the sigmoid. Gastrointest Endosc. 1996 Dec; 44(6):739-41. Vandervoort J, Weiss EJ, Somnay K, Tham TC, Wong RC, Carr-Locke DL. PMID: 8979071.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    31. A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med. 1996 Apr 25; 334(17):1090-4. Weiss EJ, Bray PF, Tayback M, Schulman SP, Kickler TS, Becker LC, Weiss JL, Gerstenblith G, Goldschmidt-Clermont PJ. PMID: 8598867.
      View in: PubMed   Mentions: 76     Fields:    Translation:Humans
    32. A monoclonal antibody (SZ21) specific for platelet GPIIIa distinguishes P1A1 from P1A2. Tissue Antigens. 1995 Nov; 46(5):374-81. Weiss EJ, Goldschmidt-Clermont PJ, Grigoryev D, Jin Y, Kickler TS, Bray PF. PMID: 8838346.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
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